Drosophila melanogaster

89 known processes

Sra-1 (Dmel_CG4931)

specifically Rac1-associated protein 1

(Aliases: CYFIP1/2,PIR121,dSra,Dmel\CG4931,DSra-1,Sra,CYFIP,Sra1,CG4931,PIR121/Sra-1,Sra1/PIR121,sra1)

Sra-1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
synapse organization GO:0050808 196 0.967
morphogenesis of an epithelium GO:0002009 276 0.948
actin cytoskeleton organization GO:0030036 206 0.929
epithelial cell migration GO:0010631 148 0.923
cortical actin cytoskeleton organization GO:0030866 24 0.922
eye morphogenesis GO:0048592 260 0.875
cell projection assembly GO:0030031 94 0.869
positive regulation of actin filament polymerization GO:0030838 11 0.849
axon development GO:0061564 297 0.849
regulation of axonogenesis GO:0050770 32 0.768
lamellipodium organization GO:0097581 21 0.760
Mouse
epithelium migration GO:0090132 148 0.734
positive regulation of cellular component organization GO:0051130 156 0.731
embryonic morphogenesis GO:0048598 206 0.714
Worm
neuromuscular junction development GO:0007528 149 0.710
growth GO:0040007 359 0.707
actin filament organization GO:0007015 126 0.677
ameboidal type cell migration GO:0001667 151 0.673
synapse assembly GO:0007416 143 0.644
programmed cell death GO:0012501 257 0.628
Human
regulation of response to external stimulus GO:0032101 115 0.610
neurological system process GO:0050877 358 0.606
regulation of anatomical structure morphogenesis GO:0022603 242 0.601
positive regulation of response to stimulus GO:0048584 323 0.600
arp2 3 complex mediated actin nucleation GO:0034314 3 0.598
intracellular signal transduction GO:0035556 300 0.586
tissue morphogenesis GO:0048729 297 0.574
Zebrafish
axon extension involved in axon guidance GO:0048846 10 0.563
cell motility GO:0048870 251 0.551
Worm
actin filament based process GO:0030029 220 0.551
regulation of catalytic activity GO:0050790 185 0.546
Human
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.540
metal ion transport GO:0030001 74 0.540
regulation of actin filament polymerization GO:0030833 25 0.532
stress activated mapk cascade GO:0051403 52 0.498
regulation of protein polymerization GO:0032271 28 0.482
cell death GO:0008219 279 0.482
Human
phosphorylation GO:0016310 294 0.451
cellular macromolecular complex assembly GO:0034622 153 0.449
regulation of phosphorus metabolic process GO:0051174 210 0.444
regulation of nervous system development GO:0051960 248 0.437
regulation of synapse organization GO:0050807 110 0.437
branching morphogenesis of an epithelial tube GO:0048754 45 0.434
regulation of growth GO:0040008 233 0.434
cell proliferation GO:0008283 299 0.428
embryonic organ development GO:0048568 50 0.427
embryo development ending in birth or egg hatching GO:0009792 152 0.424
Worm
regulation of phosphate metabolic process GO:0019220 210 0.404
regulation of actin filament based process GO:0032970 42 0.397
developmental growth GO:0048589 280 0.391
lamellipodium assembly GO:0030032 21 0.384
Mouse
signal transduction by phosphorylation GO:0023014 107 0.367
regulation of synapse structure and activity GO:0050803 128 0.359
morphogenesis of a branching epithelium GO:0061138 45 0.358
apoptotic signaling pathway GO:0097190 27 0.351
establishment or maintenance of cell polarity GO:0007163 167 0.348
regulation of developmental growth GO:0048638 174 0.346
regulation of actin polymerization or depolymerization GO:0008064 27 0.345
mapk cascade GO:0000165 107 0.344
mesenchyme development GO:0060485 9 0.340
cellularization GO:0007349 90 0.335
heart development GO:0007507 82 0.332
tube morphogenesis GO:0035239 191 0.329
regulation of cellular component movement GO:0051270 42 0.323
protein complex assembly GO:0006461 200 0.322
axonogenesis GO:0007409 290 0.317
immune system process GO:0002376 347 0.316
regulation of cell morphogenesis GO:0022604 163 0.315
tube development GO:0035295 244 0.312
syncytium formation GO:0006949 43 0.312
synaptic growth at neuromuscular junction GO:0051124 119 0.311
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.304
regulation of synapse assembly GO:0051963 94 0.296
epithelial cell development GO:0002064 274 0.292
morphogenesis of embryonic epithelium GO:0016331 94 0.283
germarium derived egg chamber formation GO:0007293 101 0.273
myoblast fusion GO:0007520 43 0.263
negative regulation of cellular component organization GO:0051129 108 0.262
endocytosis GO:0006897 310 0.261
cell division GO:0051301 248 0.257
small gtpase mediated signal transduction GO:0007264 88 0.256
developmental cell growth GO:0048588 52 0.250
response to abiotic stimulus GO:0009628 341 0.244
immune effector process GO:0002252 98 0.236
oocyte microtubule cytoskeleton organization GO:0016325 35 0.231
positive regulation of macromolecule metabolic process GO:0010604 405 0.225
Human
cellular component assembly involved in morphogenesis GO:0010927 151 0.223
regulation of phosphorylation GO:0042325 147 0.223
filopodium assembly GO:0046847 33 0.218
cell cell signaling involved in cell fate commitment GO:0045168 210 0.214
regulation of axon extension involved in axon guidance GO:0048841 4 0.213
ovarian follicle cell development GO:0030707 248 0.213
macromolecular complex assembly GO:0065003 256 0.213
regulation of cell death GO:0010941 173 0.211
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.207
regulation of peptidase activity GO:0052547 39 0.207
Human
forebrain development GO:0030900 2 0.206
regulation of cell shape GO:0008360 113 0.200
actin polymerization or depolymerization GO:0008154 31 0.200
neuron projection extension GO:1990138 32 0.197
positive regulation of jun kinase activity GO:0043507 4 0.192
nucleoside phosphate catabolic process GO:1901292 110 0.192
dna metabolic process GO:0006259 227 0.189
axon extension GO:0048675 32 0.185
actin cytoskeleton reorganization GO:0031532 22 0.185
organophosphate metabolic process GO:0019637 195 0.185
purine nucleoside triphosphate metabolic process GO:0009144 119 0.179
collateral sprouting GO:0048668 3 0.178
cellular protein modification process GO:0006464 438 0.175
mrna polyadenylation GO:0006378 11 0.172
telencephalon development GO:0021537 2 0.170
regulation of apoptotic process GO:0042981 130 0.169
response to external biotic stimulus GO:0043207 293 0.168
semaphorin plexin signaling pathway GO:0071526 4 0.167
protein modification process GO:0036211 438 0.166
regulation of anatomical structure size GO:0090066 163 0.163
positive regulation of cell communication GO:0010647 250 0.161
tissue migration GO:0090130 155 0.160
taxis GO:0042330 304 0.159
negative regulation of signaling GO:0023057 219 0.157
regulation of axon guidance GO:1902667 10 0.157
positive regulation of cytoskeleton organization GO:0051495 21 0.153
cortical cytoskeleton organization GO:0030865 29 0.152
positive regulation of protein metabolic process GO:0051247 128 0.152
Human
actin filament polymerization GO:0030041 27 0.150
nucleotide metabolic process GO:0009117 161 0.147
muscle cell differentiation GO:0042692 103 0.146
regulation of immune system process GO:0002682 176 0.145
positive regulation of cellular component biogenesis GO:0044089 80 0.142
positive regulation of actin nucleation GO:0051127 1 0.139
regulation of protein metabolic process GO:0051246 256 0.137
Human
regulation of notch signaling pathway GO:0008593 100 0.134
regulation of filopodium assembly GO:0051489 24 0.134
negative regulation of cell communication GO:0010648 223 0.134
gliogenesis GO:0042063 80 0.133
single organism intracellular transport GO:1902582 207 0.133
regulation of cellular protein metabolic process GO:0032268 243 0.131
Human
positive regulation of biosynthetic process GO:0009891 316 0.130
regulation of transferase activity GO:0051338 58 0.130
cellular protein complex assembly GO:0043623 71 0.129
digestive tract morphogenesis GO:0048546 127 0.127
regulation of jnk cascade GO:0046328 40 0.125
regulation of cellular component size GO:0032535 98 0.125
ribonucleoside triphosphate catabolic process GO:0009203 108 0.124
small molecule metabolic process GO:0044281 305 0.123
digestive system development GO:0055123 149 0.121
regulation of mapk cascade GO:0043408 92 0.120
protein polymerization GO:0051258 42 0.120
endosomal transport GO:0016197 44 0.118
ras protein signal transduction GO:0007265 88 0.118
organelle assembly GO:0070925 198 0.117
regulation of actin nucleation GO:0051125 3 0.117
lateral inhibition GO:0046331 206 0.115
carbohydrate derivative metabolic process GO:1901135 217 0.115
regulation of cell projection organization GO:0031344 92 0.115
cell growth GO:0016049 108 0.115
regulation of cellular component biogenesis GO:0044087 201 0.114
zymogen activation GO:0031638 20 0.112
Human
regulation of cell migration GO:0030334 22 0.109
actin nucleation GO:0045010 8 0.109
germ line cyst formation GO:0048134 44 0.107
positive regulation of signaling GO:0023056 243 0.106
ribonucleoside metabolic process GO:0009119 127 0.104
positive regulation of phosphorylation GO:0042327 87 0.102
compound eye development GO:0048749 307 0.101
positive regulation of axonogenesis GO:0050772 2 0.100
morphogenesis of a branching structure GO:0001763 45 0.100
sensory organ morphogenesis GO:0090596 260 0.100
biological adhesion GO:0022610 138 0.099
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.098
negative regulation of developmental growth GO:0048640 64 0.097
regulation of actin filament length GO:0030832 27 0.096
regulation of cell cycle process GO:0010564 181 0.096
apoptotic process GO:0006915 159 0.095
Human
negative regulation of response to stimulus GO:0048585 258 0.094
purine containing compound catabolic process GO:0072523 112 0.094
positive regulation of phosphate metabolic process GO:0045937 139 0.093
photoreceptor cell axon guidance GO:0072499 23 0.093
positive regulation of molecular function GO:0044093 136 0.092
Human
positive regulation of signal transduction GO:0009967 223 0.092
stress activated protein kinase signaling cascade GO:0031098 55 0.092
glycosyl compound catabolic process GO:1901658 112 0.092
regulation of rho gtpase activity GO:0032319 20 0.092
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.091
regulation of intracellular signal transduction GO:1902531 236 0.090
positive regulation of protein polymerization GO:0032273 14 0.090
axon guidance GO:0007411 233 0.090
gonad development GO:0008406 50 0.089
Worm
female germ line cyst formation GO:0048135 42 0.088
regulation of actin cytoskeleton organization GO:0032956 42 0.087
regulation of response to stress GO:0080134 200 0.087
establishment of localization in cell GO:0051649 402 0.087
regulation of cell development GO:0060284 215 0.086
positive regulation of cellular protein metabolic process GO:0032270 118 0.083
Human
purine nucleoside triphosphate catabolic process GO:0009146 108 0.082
purine nucleotide metabolic process GO:0006163 146 0.082
regulation of cell cycle GO:0051726 291 0.081
rac protein signal transduction GO:0016601 3 0.080
protein complex biogenesis GO:0070271 201 0.080
regulation of chemotaxis GO:0050920 12 0.080
phagocytosis GO:0006909 215 0.079
cardiovascular system development GO:0072358 82 0.078
regulation of programmed cell death GO:0043067 152 0.077
regulation of cytoskeleton organization GO:0051493 89 0.077
oocyte fate determination GO:0030716 27 0.077
regulation of protein kinase activity GO:0045859 51 0.076
gastrulation GO:0007369 70 0.076
negative regulation of cytoskeleton organization GO:0051494 30 0.075
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.074
regulation of protein modification process GO:0031399 112 0.073
nucleoside catabolic process GO:0009164 112 0.073
regulation of kinase activity GO:0043549 53 0.073
regulation of photoreceptor cell axon guidance GO:2000289 5 0.071
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.070
regulation of axon extension GO:0030516 8 0.070
endoderm formation GO:0001706 3 0.067
positive regulation of protein complex assembly GO:0031334 22 0.067
regionalization GO:0003002 416 0.067
meiotic cell cycle GO:0051321 171 0.067
regulation of organelle organization GO:0033043 196 0.067
intracellular transport GO:0046907 228 0.066
nucleobase containing compound catabolic process GO:0034655 165 0.065
lipid metabolic process GO:0006629 121 0.065
regulation of receptor mediated endocytosis GO:0048259 9 0.065
regulation of cell growth GO:0001558 43 0.064
negative regulation of organelle organization GO:0010639 56 0.064
cellular lipid metabolic process GO:0044255 83 0.063
positive regulation of cell motility GO:2000147 3 0.063
positive regulation of cell migration GO:0030335 2 0.062
positive regulation of developmental process GO:0051094 143 0.061
myotube differentiation GO:0014902 46 0.061
neuron migration GO:0001764 5 0.061
regulation of localization GO:0032879 275 0.061
regulation of rho protein signal transduction GO:0035023 20 0.060
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.059
purine ribonucleoside metabolic process GO:0046128 127 0.057
regulation of map kinase activity GO:0043405 17 0.057
negative regulation of signal transduction GO:0009968 206 0.056
transcription from rna polymerase ii promoter GO:0006366 368 0.055
positive regulation of phosphorus metabolic process GO:0010562 139 0.054
organonitrogen compound catabolic process GO:1901565 128 0.054
positive regulation of intracellular signal transduction GO:1902533 116 0.054
embryonic organ morphogenesis GO:0048562 5 0.053
regulation of molecular function GO:0065009 217 0.053
Human
regulation of endopeptidase activity GO:0052548 36 0.052
Human
regulation of small gtpase mediated signal transduction GO:0051056 93 0.052
organophosphate catabolic process GO:0046434 112 0.051
syncytium formation by plasma membrane fusion GO:0000768 43 0.051
positive regulation of catalytic activity GO:0043085 118 0.050
Human
regulation of epithelial cell migration GO:0010632 12 0.050
establishment of organelle localization GO:0051656 122 0.050
regulation of locomotion GO:0040012 42 0.049
positive regulation of filopodium assembly GO:0051491 15 0.049
cellular protein localization GO:0034613 160 0.049
epithelial cell differentiation GO:0030855 322 0.048
epithelial tube morphogenesis GO:0060562 88 0.047
cellular catabolic process GO:0044248 372 0.046
single organism behavior GO:0044708 391 0.046
regulation of cell projection assembly GO:0060491 30 0.045
regulation of cell proliferation GO:0042127 163 0.045
endodermal cell fate commitment GO:0001711 3 0.044
blastoderm segmentation GO:0007350 159 0.044
hematopoietic or lymphoid organ development GO:0048534 57 0.044
regulation of cellular ketone metabolic process GO:0010565 3 0.044
negative regulation of rna metabolic process GO:0051253 251 0.043
developmental growth involved in morphogenesis GO:0060560 65 0.042
purine nucleoside catabolic process GO:0006152 112 0.042
regulation of endocytosis GO:0030100 37 0.042
nucleotide catabolic process GO:0009166 109 0.041
heterocycle catabolic process GO:0046700 166 0.041
oxoacid metabolic process GO:0043436 103 0.041
negative regulation of epithelial cell migration GO:0010633 1 0.041
positive regulation of mapk cascade GO:0043410 63 0.040
locomotory behavior GO:0007626 176 0.040
eye photoreceptor cell differentiation GO:0001754 145 0.040
development of primary sexual characteristics GO:0045137 50 0.040
Worm
ribonucleoside catabolic process GO:0042454 112 0.039
ribonucleotide catabolic process GO:0009261 109 0.039
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.039
gtp catabolic process GO:0006184 72 0.038
endoderm development GO:0007492 6 0.038
regulation of cell differentiation GO:0045595 302 0.038
cellular nitrogen compound catabolic process GO:0044270 165 0.038
jnk cascade GO:0007254 50 0.038
synaptic transmission GO:0007268 288 0.038
nucleoside triphosphate metabolic process GO:0009141 120 0.037
positive regulation of cell proliferation GO:0008284 47 0.037
cell activation GO:0001775 9 0.037
negative regulation of nervous system development GO:0051961 92 0.037
regulation of protein complex assembly GO:0043254 42 0.037
axon regeneration GO:0031103 8 0.037
protein processing GO:0016485 68 0.036
Human
defense response GO:0006952 300 0.036
regulation of hydrolase activity GO:0051336 97 0.036
Human
positive regulation of protein phosphorylation GO:0001934 34 0.036
catabolic process GO:0009056 409 0.035
cell type specific apoptotic process GO:0097285 38 0.035
regulation of ras protein signal transduction GO:0046578 93 0.035
negative regulation of gene expression GO:0010629 387 0.035
organic cyclic compound catabolic process GO:1901361 168 0.035
determination of adult lifespan GO:0008340 137 0.034
establishment of cell polarity GO:0030010 40 0.034
posttranscriptional regulation of gene expression GO:0010608 145 0.034
amine metabolic process GO:0009308 12 0.034
regulation of multicellular organismal development GO:2000026 414 0.034
regulation of phagocytosis engulfment GO:0060099 1 0.034
neuron projection extension involved in neuron projection guidance GO:1902284 10 0.033
regulation of cell motility GO:2000145 23 0.033
regulation of gtpase activity GO:0043087 44 0.033
negative regulation of cell death GO:0060548 81 0.033
localization of cell GO:0051674 257 0.033
Worm
positive regulation of multicellular organismal process GO:0051240 143 0.033
immune system development GO:0002520 57 0.033
cellular response to dna damage stimulus GO:0006974 223 0.033
organelle localization GO:0051640 148 0.032
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.032
activation of jun kinase activity GO:0007257 3 0.032
aromatic compound catabolic process GO:0019439 166 0.031
positive regulation of cell death GO:0010942 69 0.031
appendage morphogenesis GO:0035107 397 0.031
regulation of protein serine threonine kinase activity GO:0071900 25 0.031
segmentation GO:0035282 207 0.031
single organism cellular localization GO:1902580 180 0.030
open tracheal system development GO:0007424 204 0.030
regulation of neuron projection development GO:0010975 69 0.030
actin filament bundle organization GO:0061572 28 0.030
regulation of neurogenesis GO:0050767 158 0.030
cellular response to molecule of bacterial origin GO:0071219 3 0.030
positive regulation of transcription dna templated GO:0045893 266 0.030
death GO:0016265 284 0.030
Human
positive regulation of synaptic growth at neuromuscular junction GO:0045887 26 0.030
positive regulation of axon extension GO:0045773 2 0.030
endodermal cell differentiation GO:0035987 3 0.030
cation transport GO:0006812 110 0.030
meiotic nuclear division GO:0007126 151 0.029
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.029
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.029
photoreceptor cell differentiation GO:0046530 170 0.029
neural precursor cell proliferation GO:0061351 75 0.029
nucleobase containing small molecule metabolic process GO:0055086 174 0.029
regulation of vesicle mediated transport GO:0060627 59 0.029
periodic partitioning GO:0007365 29 0.028
larval development GO:0002164 104 0.028
Worm
membrane organization GO:0061024 112 0.028
erk1 and erk2 cascade GO:0070371 39 0.027
endomembrane system organization GO:0010256 119 0.027
receptor mediated endocytosis GO:0006898 21 0.027
immune response GO:0006955 246 0.027
germ cell migration GO:0008354 43 0.027
guanosine containing compound catabolic process GO:1901069 74 0.027
organonitrogen compound metabolic process GO:1901564 318 0.027
wound healing GO:0042060 75 0.026
unidimensional cell growth GO:0009826 15 0.026
positive regulation of apoptotic process GO:0043065 47 0.026
purine ribonucleoside catabolic process GO:0046130 112 0.026
organic substance catabolic process GO:1901575 308 0.026
establishment or maintenance of monopolar cell polarity GO:0061339 15 0.026
dendrite development GO:0016358 204 0.025
Worm
positive regulation of phagocytosis engulfment GO:0060100 1 0.025
cell adhesion GO:0007155 136 0.025
nucleoside metabolic process GO:0009116 127 0.025
regulation of neuron death GO:1901214 26 0.025
germarium derived female germ line cyst formation GO:0030727 42 0.025
protein localization GO:0008104 284 0.025
positive regulation of organelle organization GO:0010638 65 0.025
carboxylic acid metabolic process GO:0019752 92 0.024
glial cell migration GO:0008347 31 0.024
circulatory system development GO:0072359 82 0.024
purine nucleoside metabolic process GO:0042278 127 0.024
positive regulation of cell adhesion GO:0045785 10 0.024
phagocytosis engulfment GO:0006911 11 0.024
positive regulation of transferase activity GO:0051347 26 0.024
substrate dependent cell migration GO:0006929 3 0.023
regulation of neuron differentiation GO:0045664 103 0.023
germarium derived oocyte fate determination GO:0007294 26 0.023
ion transport GO:0006811 145 0.023
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.023
negative regulation of growth GO:0045926 84 0.023
ribose phosphate metabolic process GO:0019693 145 0.023
protein phosphorylation GO:0006468 169 0.023
production of sirna involved in rna interference GO:0030422 11 0.023
regulation of apoptotic signaling pathway GO:2001233 10 0.023
regulation of extent of cell growth GO:0061387 8 0.023
regulation of mitotic cell cycle GO:0007346 190 0.023
positive regulation of rna biosynthetic process GO:1902680 266 0.022
response to radiation GO:0009314 155 0.022
embryonic development via the syncytial blastoderm GO:0001700 148 0.022
regulation of cellular response to stress GO:0080135 89 0.022
positive regulation of synapse assembly GO:0051965 29 0.022
axon midline choice point recognition GO:0016199 26 0.022
learning or memory GO:0007611 141 0.021
positive regulation of receptor mediated endocytosis GO:0048260 7 0.021
negative regulation of molecular function GO:0044092 51 0.021
defense response to other organism GO:0098542 225 0.021
hindbrain development GO:0030902 2 0.021
glycosyl compound metabolic process GO:1901657 127 0.021
positive regulation of cell projection organization GO:0031346 29 0.021
ribonucleotide metabolic process GO:0009259 145 0.021
carbohydrate derivative catabolic process GO:1901136 118 0.020
rna localization GO:0006403 115 0.020
notch signaling pathway GO:0007219 120 0.020
positive regulation of kinase activity GO:0033674 25 0.020
hemopoiesis GO:0030097 46 0.020
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 1 0.020
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.020
Human
positive regulation of hydrolase activity GO:0051345 78 0.020
Human
regulation of cellular catabolic process GO:0031329 157 0.020
negative regulation of erk1 and erk2 cascade GO:0070373 3 0.020
response to wounding GO:0009611 94 0.019
dorsal ventral axon guidance GO:0033563 2 0.019
regulation of microtubule cytoskeleton organization GO:0070507 41 0.019
organic acid metabolic process GO:0006082 103 0.019
axon choice point recognition GO:0016198 26 0.019
peptidyl tyrosine modification GO:0018212 24 0.019
pseudocleavage involved in syncytial blastoderm formation GO:0030589 9 0.019
positive regulation of cell development GO:0010720 61 0.019
response to other organism GO:0051707 293 0.018
regulation of cell size GO:0008361 63 0.018
sex differentiation GO:0007548 81 0.018
Worm
production of small rna involved in gene silencing by rna GO:0070918 15 0.018
single organism catabolic process GO:0044712 228 0.018
positive regulation of jnk cascade GO:0046330 16 0.018
positive regulation of developmental growth GO:0048639 62 0.018
nucleoside triphosphate catabolic process GO:0009143 108 0.018
mrna metabolic process GO:0016071 124 0.018
skin development GO:0043588 65 0.018
proteolysis GO:0006508 192 0.018
Human
positive regulation of cell morphogenesis involved in differentiation GO:0010770 12 0.018
vesicle mediated transport GO:0016192 381 0.018
positive regulation of nucleic acid templated transcription GO:1903508 266 0.018
production of mirnas involved in gene silencing by mirna GO:0035196 10 0.017
dendrite self avoidance GO:0070593 8 0.017
regulation of ras gtpase activity GO:0032318 38 0.017
anterior posterior pattern specification GO:0009952 136 0.017
positive regulation of rab gtpase activity GO:0032851 7 0.017
positive regulation of phagocytosis GO:0050766 3 0.017
positive regulation of cellular biosynthetic process GO:0031328 316 0.017
positive regulation of transport GO:0051050 92 0.017
compound eye photoreceptor cell differentiation GO:0001751 140 0.017
positive regulation of lipid metabolic process GO:0045834 4 0.017
regulation of intracellular transport GO:0032386 64 0.017
positive regulation of nervous system development GO:0051962 69 0.017
negative regulation of multicellular organismal process GO:0051241 142 0.017
single organismal cell cell adhesion GO:0016337 45 0.016
Human
regulation of cell adhesion GO:0030155 27 0.016
cell migration GO:0016477 238 0.016
Worm
detection of external stimulus GO:0009581 66 0.016
olfactory bulb axon guidance GO:0071678 3 0.016
mesenchymal cell differentiation GO:0048762 1 0.016
inositol lipid mediated signaling GO:0048017 4 0.016
neuromuscular synaptic transmission GO:0007274 67 0.016
ribonucleoside monophosphate catabolic process GO:0009158 39 0.016
head development GO:0060322 135 0.016
central nervous system neuron axonogenesis GO:0021955 7 0.016
positive regulation of axon guidance GO:1902669 1 0.016
meiotic cell cycle process GO:1903046 132 0.015
branching involved in open tracheal system development GO:0060446 45 0.015
regulation of protein localization GO:0032880 76 0.015
chaeta development GO:0022416 97 0.015
chaeta morphogenesis GO:0008407 42 0.015
cellular response to hexose stimulus GO:0071331 1 0.015
smoothened signaling pathway GO:0007224 49 0.015
establishment of ommatidial planar polarity GO:0042067 49 0.015
oviposition GO:0018991 19 0.015
positive regulation of gene expression GO:0010628 290 0.015
positive regulation of proteolysis GO:0045862 52 0.015
Human
anion transport GO:0006820 41 0.014
regulation of transport GO:0051049 181 0.014
regulation of cellular localization GO:0060341 136 0.014
protein maturation GO:0051604 71 0.014
Human
negative regulation of programmed cell death GO:0043069 72 0.014
establishment of rna localization GO:0051236 47 0.014
positive regulation of immune system process GO:0002684 68 0.014
regulation of behavior GO:0050795 75 0.014
positive regulation of stress fiber assembly GO:0051496 3 0.014
negative regulation of cellular metabolic process GO:0031324 382 0.014
cellular ketone metabolic process GO:0042180 24 0.014
central nervous system neuron differentiation GO:0021953 8 0.014
positive regulation of cell differentiation GO:0045597 64 0.014
central nervous system projection neuron axonogenesis GO:0021952 6 0.014
cellular response to biotic stimulus GO:0071216 4 0.014
positive regulation of stress activated mapk cascade GO:0032874 17 0.014
semaphorin plexin signaling pathway involved in regulation of photoreceptor cell axon guidance GO:2000305 2 0.014
retina morphogenesis in camera type eye GO:0060042 2 0.013
Zebrafish
membrane invagination GO:0010324 11 0.013
regulation of embryonic cell shape GO:0016476 30 0.013
protein destabilization GO:0031648 2 0.013
phospholipid metabolic process GO:0006644 23 0.013
response to biotic stimulus GO:0009607 294 0.013
regulation of immune response GO:0050776 118 0.013
negative regulation of protein metabolic process GO:0051248 85 0.013

Sra-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.045
sensory system disease DOID:0050155 0 0.022
eye and adnexa disease DOID:1492 0 0.022
nervous system disease DOID:863 0 0.022
eye disease DOID:5614 0 0.022