Drosophila melanogaster

160 known processes

cic (Dmel_CG5067)

capicua

(Aliases: Cic,Dmel\CG5067,CG5067,fet,E(Dl)D49)

cic biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regionalization GO:0003002 416 0.994
wing disc morphogenesis GO:0007472 344 0.929
imaginal disc derived appendage morphogenesis GO:0035114 395 0.740
appendage morphogenesis GO:0035107 397 0.696
imaginal disc derived appendage development GO:0048737 399 0.680
segmentation GO:0035282 207 0.662
imaginal disc derived wing morphogenesis GO:0007476 337 0.605
blastoderm segmentation GO:0007350 159 0.585
negative regulation of response to stimulus GO:0048585 258 0.548
stem cell differentiation GO:0048863 117 0.548
zygotic determination of anterior posterior axis embryo GO:0007354 27 0.489
appendage development GO:0048736 401 0.459
axonogenesis GO:0007409 290 0.444
enzyme linked receptor protein signaling pathway GO:0007167 179 0.398
negative regulation of cell communication GO:0010648 223 0.364
compound eye photoreceptor fate commitment GO:0001752 36 0.361
epithelial cell migration GO:0010631 148 0.319
stem cell maintenance GO:0019827 67 0.318
axon development GO:0061564 297 0.304
eggshell formation GO:0030703 105 0.303
post embryonic appendage morphogenesis GO:0035120 385 0.275
regulation of developmental growth GO:0048638 174 0.274
positive regulation of biosynthetic process GO:0009891 316 0.273
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.262
sensory organ morphogenesis GO:0090596 260 0.255
positive regulation of cellular biosynthetic process GO:0031328 316 0.254
chorion containing eggshell formation GO:0007304 105 0.254
epithelial cell differentiation GO:0030855 322 0.254
tube morphogenesis GO:0035239 191 0.197
cellular response to chemical stimulus GO:0070887 199 0.179
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.167
response to organic substance GO:0010033 284 0.161
growth GO:0040007 359 0.158
positive regulation of macromolecule metabolic process GO:0010604 405 0.154
terminal region determination GO:0007362 25 0.149
negative regulation of signal transduction GO:0009968 206 0.143
dorsal ventral pattern formation GO:0009953 133 0.136
muscle organ development GO:0007517 127 0.126
negative regulation of developmental process GO:0051093 201 0.125
eye photoreceptor cell fate commitment GO:0042706 37 0.123
embryonic pattern specification GO:0009880 174 0.123
regulation of cellular protein metabolic process GO:0032268 243 0.122
regulation of multicellular organism growth GO:0040014 40 0.117
neuron projection guidance GO:0097485 241 0.117
response to external biotic stimulus GO:0043207 293 0.112
negative regulation of multicellular organismal process GO:0051241 142 0.104
imaginal disc derived wing vein specification GO:0007474 48 0.104
epithelial cell development GO:0002064 274 0.104
gland morphogenesis GO:0022612 145 0.103
eye development GO:0001654 323 0.100
axis specification GO:0009798 167 0.094
torso signaling pathway GO:0008293 21 0.092
regulation of localization GO:0032879 275 0.091
negative regulation of protein tyrosine kinase activity GO:0061099 5 0.088
cellular response to organic cyclic compound GO:0071407 32 0.087
gland development GO:0048732 191 0.086
epithelium migration GO:0090132 148 0.085
developmental growth GO:0048589 280 0.084
compound eye development GO:0048749 307 0.082
maintenance of gastrointestinal epithelium GO:0030277 3 0.081
stem cell development GO:0048864 79 0.081
ectodermal placode morphogenesis GO:0071697 4 0.081
multicellular organism growth GO:0035264 46 0.080
dorsal ventral axis specification ovarian follicular epithelium GO:0008069 13 0.078
reproductive structure development GO:0048608 74 0.077
cell division GO:0051301 248 0.076
response to biotic stimulus GO:0009607 294 0.075
cell migration GO:0016477 238 0.074
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.074
single organism behavior GO:0044708 391 0.074
neuroblast fate determination GO:0007400 12 0.072
positive regulation of gene expression GO:0010628 290 0.071
regulation of transport GO:0051049 181 0.070
embryo development ending in birth or egg hatching GO:0009792 152 0.069
cell fate determination GO:0001709 91 0.067
body morphogenesis GO:0010171 2 0.067
establishment of tissue polarity GO:0007164 87 0.067
cell maturation GO:0048469 144 0.067
ectodermal placode formation GO:0060788 4 0.067
positive regulation of nucleic acid templated transcription GO:1903508 266 0.066
protein maturation GO:0051604 71 0.066
protein transport GO:0015031 155 0.064
protein targeting GO:0006605 64 0.064
eggshell chorion assembly GO:0007306 66 0.064
regulation of protein metabolic process GO:0051246 256 0.064
camera type eye development GO:0043010 4 0.063
positive regulation of transcription dna templated GO:0045893 266 0.063
open tracheal system development GO:0007424 204 0.063
cell proliferation GO:0008283 299 0.063
vitelline membrane formation GO:0030704 11 0.062
cell fate specification GO:0001708 71 0.060
lateral inhibition GO:0046331 206 0.058
establishment of localization in cell GO:0051649 402 0.058
positive regulation of rna metabolic process GO:0051254 271 0.058
cellular protein modification process GO:0006464 438 0.057
establishment or maintenance of apical basal cell polarity GO:0035088 34 0.057
larval development GO:0002164 104 0.057
sex differentiation GO:0007548 81 0.057
response to endogenous stimulus GO:0009719 119 0.055
reproductive system development GO:0061458 74 0.055
eye morphogenesis GO:0048592 260 0.055
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.054
negative regulation of cell differentiation GO:0045596 143 0.054
stem cell fate commitment GO:0048865 25 0.053
tube development GO:0035295 244 0.053
neurological system process GO:0050877 358 0.051
response to other organism GO:0051707 293 0.051
positive regulation of rna biosynthetic process GO:1902680 266 0.050
multicellular organismal homeostasis GO:0048871 41 0.049
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.049
anterior posterior axis specification embryo GO:0008595 103 0.048
negative regulation of cell proliferation GO:0008285 69 0.047
imaginal disc pattern formation GO:0007447 91 0.045
peptidyl amino acid modification GO:0018193 105 0.045
regulation of protein localization GO:0032880 76 0.044
anterior posterior axis specification GO:0009948 109 0.044
regulation of programmed cell death GO:0043067 152 0.044
cell cell signaling involved in cell fate commitment GO:0045168 210 0.044
protein localization GO:0008104 284 0.043
single organism biosynthetic process GO:0044711 206 0.043
negative regulation of epithelial cell proliferation GO:0050680 4 0.043
positive regulation of signal transduction GO:0009967 223 0.043
oxoacid metabolic process GO:0043436 103 0.042
positive regulation of protein metabolic process GO:0051247 128 0.042
photoreceptor cell fate commitment GO:0046552 41 0.042
positive regulation of response to stimulus GO:0048584 323 0.041
catabolic process GO:0009056 409 0.041
olfactory behavior GO:0042048 97 0.041
tissue migration GO:0090130 155 0.040
establishment or maintenance of polarity of follicular epithelium GO:0016334 26 0.040
intracellular protein transport GO:0006886 104 0.040
ameboidal type cell migration GO:0001667 151 0.039
cell death GO:0008219 279 0.038
tripartite regional subdivision GO:0007351 103 0.038
regulation of transferase activity GO:0051338 58 0.038
protein targeting to nucleus GO:0044744 51 0.037
cellular component assembly involved in morphogenesis GO:0010927 151 0.037
r7 cell fate commitment GO:0007465 12 0.037
negative regulation of signaling GO:0023057 219 0.037
neuroblast fate commitment GO:0014017 19 0.037
erbb signaling pathway GO:0038127 58 0.036
muscle structure development GO:0061061 224 0.036
heart development GO:0007507 82 0.035
regulation of defense response GO:0031347 102 0.035
ovarian follicle cell development GO:0030707 248 0.035
positive regulation of cellular protein metabolic process GO:0032270 118 0.035
cytoplasmic transport GO:0016482 130 0.034
mitotic cytokinesis GO:0000281 50 0.033
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.033
regulation of cell proliferation GO:0042127 163 0.033
digestive tract morphogenesis GO:0048546 127 0.033
transcription from rna polymerase ii promoter GO:0006366 368 0.032
response to alcohol GO:0097305 95 0.032
pole plasm protein localization GO:0007318 10 0.032
head development GO:0060322 135 0.032
anterior posterior pattern specification GO:0009952 136 0.030
epithelial structure maintenance GO:0010669 17 0.030
phagocytosis GO:0006909 215 0.029
mesoderm development GO:0007498 78 0.028
cell motility GO:0048870 251 0.028
regulation of cell death GO:0010941 173 0.028
protein modification process GO:0036211 438 0.027
dorsal ventral axis specification GO:0009950 66 0.027
regulation of cellular localization GO:0060341 136 0.027
innate immune response GO:0045087 144 0.027
protein localization to organelle GO:0033365 82 0.027
localization of cell GO:0051674 257 0.025
retina development in camera type eye GO:0060041 4 0.025
stem cell fate determination GO:0048867 15 0.025
protein import into nucleus GO:0006606 51 0.025
germarium derived oocyte fate determination GO:0007294 26 0.025
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 18 0.025
vesicle mediated transport GO:0016192 381 0.025
female sex differentiation GO:0046660 20 0.025
instar larval development GO:0002168 55 0.025
epithelial cell migration open tracheal system GO:0007427 32 0.024
hindgut morphogenesis GO:0007442 58 0.024
mrna processing GO:0006397 104 0.024
eye photoreceptor cell differentiation GO:0001754 145 0.024
proteolysis GO:0006508 192 0.024
protein phosphorylation GO:0006468 169 0.024
defense response GO:0006952 300 0.024
cytokinesis GO:0000910 90 0.024
protein catabolic process GO:0030163 101 0.024
defense response to bacterium GO:0042742 178 0.024
cellular protein localization GO:0034613 160 0.023
camera type eye morphogenesis GO:0048593 2 0.023
response to bacterium GO:0009617 198 0.023
chitin based embryonic cuticle biosynthetic process GO:0008362 16 0.022
cellular response to organic substance GO:0071310 132 0.022
branching morphogenesis of an epithelial tube GO:0048754 45 0.022
oocyte anterior posterior axis specification GO:0007314 72 0.022
respiratory system development GO:0060541 213 0.022
single organism intracellular transport GO:1902582 207 0.022
renal system development GO:0072001 72 0.022
development of primary sexual characteristics GO:0045137 50 0.022
defense response to other organism GO:0098542 225 0.022
death GO:0016265 284 0.022
maintenance of location GO:0051235 73 0.022
synapse assembly GO:0007416 143 0.022
regulation of molecular function GO:0065009 217 0.021
oocyte construction GO:0007308 112 0.021
anatomical structure homeostasis GO:0060249 97 0.021
establishment of protein localization GO:0045184 163 0.021
organic substance catabolic process GO:1901575 308 0.021
organic substance transport GO:0071702 257 0.021
oocyte development GO:0048599 124 0.020
positive regulation of developmental growth GO:0048639 62 0.020
autophagy GO:0006914 108 0.020
oocyte differentiation GO:0009994 145 0.020
regulation of translation GO:0006417 56 0.020
nuclear import GO:0051170 51 0.020
germ cell migration GO:0008354 43 0.020
compound eye morphogenesis GO:0001745 249 0.019
regulation of nervous system development GO:0051960 248 0.019
central nervous system development GO:0007417 201 0.019
rna localization GO:0006403 115 0.019
positive regulation of intracellular protein transport GO:0090316 30 0.019
positive regulation of signaling GO:0023056 243 0.019
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 29 0.019
gonad development GO:0008406 50 0.019
peripheral nervous system development GO:0007422 52 0.019
organic acid metabolic process GO:0006082 103 0.019
positive regulation of multicellular organism growth GO:0040018 21 0.019
cell fate commitment involved in pattern specification GO:0060581 31 0.018
apoptotic process GO:0006915 159 0.018
regulation of cell division GO:0051302 72 0.018
pole plasm assembly GO:0007315 61 0.018
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.018
oocyte microtubule cytoskeleton organization GO:0016325 35 0.018
development of primary female sexual characteristics GO:0046545 12 0.018
protein localization to nucleus GO:0034504 55 0.018
multicellular organismal reproductive behavior GO:0033057 110 0.018
regulation of apoptotic process GO:0042981 130 0.017
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.017
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 17 0.017
positive regulation of cell proliferation GO:0008284 47 0.017
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.017
negative regulation of immune system process GO:0002683 50 0.017
protein import GO:0017038 55 0.017
compound eye photoreceptor cell differentiation GO:0001751 140 0.017
neuron fate commitment GO:0048663 50 0.017
mitotic nuclear division GO:0007067 213 0.016
regulation of pole plasm oskar mrna localization GO:0007317 27 0.016
jak stat cascade GO:0007259 49 0.016
intracellular transport GO:0046907 228 0.016
single organism nuclear import GO:1902593 51 0.016
regulation of growth GO:0040008 233 0.016
olfactory learning GO:0008355 56 0.016
cellular catabolic process GO:0044248 372 0.016
morphogenesis of follicular epithelium GO:0016333 36 0.016
immune response GO:0006955 246 0.016
multi organism reproductive behavior GO:0044705 121 0.016
carboxylic acid metabolic process GO:0019752 92 0.015
positive regulation of multicellular organismal process GO:0051240 143 0.015
spermatogenesis GO:0007283 200 0.015
regulation of intracellular transport GO:0032386 64 0.015
negative regulation of transcription dna templated GO:0045892 237 0.015
negative regulation of hormone biosynthetic process GO:0032353 1 0.015
regulation of canonical wnt signaling pathway GO:0060828 15 0.015
urogenital system development GO:0001655 72 0.015
response to wounding GO:0009611 94 0.015
negative regulation of cell development GO:0010721 62 0.015
phosphorylation GO:0016310 294 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.015
oocyte axis specification GO:0007309 108 0.015
bmp signaling pathway GO:0030509 27 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.014
positive regulation of developmental process GO:0051094 143 0.014
rna interference GO:0016246 27 0.014
regulation of protein kinase activity GO:0045859 51 0.014
forebrain development GO:0030900 2 0.014
limb development GO:0060173 1 0.014
rna processing GO:0006396 147 0.014
male gamete generation GO:0048232 201 0.014
gastrulation GO:0007369 70 0.014
biological adhesion GO:0022610 138 0.014
wing and notum subfield formation GO:0035309 13 0.014
protein complex assembly GO:0006461 200 0.014
carbohydrate derivative metabolic process GO:1901135 217 0.014
hindbrain development GO:0030902 2 0.013
regulation of catalytic activity GO:0050790 185 0.013
regulation of organ growth GO:0046620 42 0.013
macromolecule catabolic process GO:0009057 161 0.013
r3 r4 cell fate commitment GO:0007464 10 0.013
single organism cellular localization GO:1902580 180 0.013
digestive tract development GO:0048565 149 0.013
protein processing GO:0016485 68 0.013
regulation of cell fate commitment GO:0010453 29 0.013
response to uv GO:0009411 24 0.013
regulation of embryonic development GO:0045995 68 0.013
negative regulation of protein metabolic process GO:0051248 85 0.013
negative regulation of growth GO:0045926 84 0.013
somatic muscle development GO:0007525 66 0.013
response to organic cyclic compound GO:0014070 89 0.013
programmed cell death GO:0012501 257 0.013
associative learning GO:0008306 65 0.013
regulation of wnt signaling pathway GO:0030111 68 0.013
brain development GO:0007420 120 0.013
cellular response to dna damage stimulus GO:0006974 223 0.013
neuroblast differentiation GO:0014016 29 0.013
regulation of photoreceptor cell differentiation GO:0046532 34 0.013
establishment or maintenance of cell polarity GO:0007163 167 0.013
organonitrogen compound metabolic process GO:1901564 318 0.013
cellular macromolecule localization GO:0070727 220 0.012
negative regulation of autophagy GO:0010507 16 0.012
motor neuron axon guidance GO:0008045 58 0.012
regulation of intracellular protein transport GO:0033157 46 0.012
formation of primary germ layer GO:0001704 24 0.012
negative regulation of nucleic acid templated transcription GO:1903507 240 0.012
negative regulation of nervous system development GO:0051961 92 0.012
regulation of secretion GO:0051046 44 0.012
regulation of immune system process GO:0002682 176 0.012
defense response to gram negative bacterium GO:0050829 94 0.012
oocyte dorsal ventral axis specification GO:0007310 34 0.012
retina morphogenesis in camera type eye GO:0060042 2 0.012
circulatory system development GO:0072359 82 0.012
positive regulation of growth GO:0045927 75 0.012
multi multicellular organism process GO:0044706 123 0.012
regulation of mitotic cell cycle phase transition GO:1901990 130 0.012
ribonucleoprotein complex subunit organization GO:0071826 28 0.012
regulation of protein serine threonine kinase activity GO:0071900 25 0.011
regulation of catabolic process GO:0009894 170 0.011
regulation of bmp signaling pathway GO:0030510 23 0.011
genital disc development GO:0035215 44 0.011
chorion containing eggshell pattern formation GO:0030381 11 0.011
regulation of cellular ketone metabolic process GO:0010565 3 0.011
ectodermal placode development GO:0071696 4 0.011
locomotory behavior GO:0007626 176 0.011
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 24 0.011
regulation of establishment of protein localization GO:0070201 61 0.011
taxis GO:0042330 304 0.011
positive regulation of cell communication GO:0010647 250 0.011
cellular amino acid metabolic process GO:0006520 61 0.011
regulation of cell cycle GO:0051726 291 0.011
asymmetric neuroblast division GO:0055059 33 0.011
epidermal growth factor receptor signaling pathway GO:0007173 58 0.011
neuroblast division GO:0055057 35 0.010
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 3 0.010
cellular response to growth factor stimulus GO:0071363 30 0.010
small molecule metabolic process GO:0044281 305 0.010
renal tubule morphogenesis GO:0061333 44 0.010
cellular macromolecular complex assembly GO:0034622 153 0.010
intracellular signal transduction GO:0035556 300 0.010
positive regulation of programmed cell death GO:0043068 62 0.010
regulation of multicellular organismal development GO:2000026 414 0.010
regulation of cell differentiation GO:0045595 302 0.010

cic disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.019
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
organ system cancer DOID:0050686 0 0.013
bone disease DOID:0080001 0 0.013
musculoskeletal system disease DOID:17 0 0.013
connective tissue disease DOID:65 0 0.013
disease of metabolism DOID:0014667 0 0.012
acquired metabolic disease DOID:0060158 0 0.012