Drosophila melanogaster

61 known processes

Vps33B (Dmel_CG5127)

Vacuolar protein sorting 33B

(Aliases: Dmel\CG5127,VPS33b,CG5127,dVps33B)

Vps33B biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
immune system process GO:0002376 347 0.382
immune response GO:0006955 246 0.361
defense response GO:0006952 300 0.146
vesicle mediated transport GO:0016192 381 0.142
Human
negative regulation of gene expression GO:0010629 387 0.119
endocytosis GO:0006897 310 0.116
response to other organism GO:0051707 293 0.116
defense response to bacterium GO:0042742 178 0.110
innate immune response GO:0045087 144 0.106
endosomal transport GO:0016197 44 0.102
response to external biotic stimulus GO:0043207 293 0.096
response to biotic stimulus GO:0009607 294 0.094
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.090
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.086
defense response to other organism GO:0098542 225 0.085
appendage development GO:0048736 401 0.077
negative regulation of biosynthetic process GO:0009890 277 0.077
intracellular signal transduction GO:0035556 300 0.074
establishment of localization in cell GO:0051649 402 0.072
negative regulation of cellular biosynthetic process GO:0031327 277 0.072
response to bacterium GO:0009617 198 0.069
protein localization GO:0008104 284 0.068
Human
positive regulation of macromolecule metabolic process GO:0010604 405 0.064
phagocytosis GO:0006909 215 0.063
establishment of protein localization GO:0045184 163 0.062
Human
post embryonic appendage morphogenesis GO:0035120 385 0.062
imaginal disc derived appendage development GO:0048737 399 0.061
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.061
transcription from rna polymerase ii promoter GO:0006366 368 0.060
positive regulation of cellular biosynthetic process GO:0031328 316 0.060
negative regulation of cellular metabolic process GO:0031324 382 0.060
positive regulation of response to stimulus GO:0048584 323 0.060
death GO:0016265 284 0.060
cell division GO:0051301 248 0.059
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.059
imaginal disc derived appendage morphogenesis GO:0035114 395 0.057
negative regulation of signaling GO:0023057 219 0.057
humoral immune response GO:0006959 117 0.056
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.056
response to extracellular stimulus GO:0009991 116 0.056
negative regulation of signal transduction GO:0009968 206 0.055
cellular protein modification process GO:0006464 438 0.055
positive regulation of signaling GO:0023056 243 0.054
organic substance transport GO:0071702 257 0.054
Human
positive regulation of rna biosynthetic process GO:1902680 266 0.054
positive regulation of rna metabolic process GO:0051254 271 0.052
response to organic substance GO:0010033 284 0.052
organelle fission GO:0048285 340 0.052
activation of innate immune response GO:0002218 4 0.052
cellular catabolic process GO:0044248 372 0.052
organelle assembly GO:0070925 198 0.050
negative regulation of transcription dna templated GO:0045892 237 0.050
defense response to gram negative bacterium GO:0050829 94 0.050
single organism membrane fusion GO:0044801 42 0.050
cellular macromolecule localization GO:0070727 220 0.050
cell death GO:0008219 279 0.049
phosphorylation GO:0016310 294 0.049
mapk cascade GO:0000165 107 0.049
antimicrobial humoral response GO:0019730 99 0.049
negative regulation of nucleic acid templated transcription GO:1903507 240 0.049
positive regulation of gene expression GO:0010628 290 0.049
positive regulation of transcription dna templated GO:0045893 266 0.047
regulation of defense response GO:0031347 102 0.047
immune effector process GO:0002252 98 0.046
cellular protein localization GO:0034613 160 0.046
positive regulation of signal transduction GO:0009967 223 0.046
negative regulation of rna biosynthetic process GO:1902679 240 0.045
appendage morphogenesis GO:0035107 397 0.045
positive regulation of programmed cell death GO:0043068 62 0.045
defense response to gram positive bacterium GO:0050830 41 0.045
response to abiotic stimulus GO:0009628 341 0.044
negative regulation of response to stimulus GO:0048585 258 0.044
tube morphogenesis GO:0035239 191 0.044
defense response to fungus GO:0050832 48 0.044
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.044
regulation of multi organism process GO:0043900 131 0.043
positive regulation of cell communication GO:0010647 250 0.043
regulation of intracellular signal transduction GO:1902531 236 0.043
regulation of mapk cascade GO:0043408 92 0.042
response to oxygen containing compound GO:1901700 200 0.041
protein modification process GO:0036211 438 0.041
negative regulation of cell communication GO:0010648 223 0.041
regulation of programmed cell death GO:0043067 152 0.041
protein phosphorylation GO:0006468 169 0.041
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.041
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.040
neurological system process GO:0050877 358 0.040
regulation of cell cycle GO:0051726 291 0.040
imaginal disc derived wing morphogenesis GO:0007476 337 0.040
regulation of biosynthetic process of antibacterial peptides active against gram positive bacteria GO:0002816 3 0.040
wing disc morphogenesis GO:0007472 344 0.040
single organism intracellular transport GO:1902582 207 0.039
membrane organization GO:0061024 112 0.038
Human
negative regulation of rna metabolic process GO:0051253 251 0.038
protein transport GO:0015031 155 0.037
Human
stem cell proliferation GO:0072089 88 0.037
regulation of catalytic activity GO:0050790 185 0.036
regulation of response to stress GO:0080134 200 0.036
pattern recognition receptor signaling pathway GO:0002221 2 0.035
membrane fusion GO:0061025 42 0.035
Human
positive regulation of nucleic acid templated transcription GO:1903508 266 0.035
cell proliferation GO:0008283 299 0.034
regulation of cellular protein metabolic process GO:0032268 243 0.034
innate immune response activating signal transduction GO:0002758 2 0.034
intracellular transport GO:0046907 228 0.034
antibacterial humoral response GO:0019731 44 0.033
regulation of phosphorus metabolic process GO:0051174 210 0.033
regulation of molecular function GO:0065009 217 0.032
regulation of phosphate metabolic process GO:0019220 210 0.032
regionalization GO:0003002 416 0.031
cytoplasmic transport GO:0016482 130 0.031
tube development GO:0035295 244 0.031
response to nutrient levels GO:0031667 114 0.031
programmed cell death GO:0012501 257 0.031
negative regulation of developmental process GO:0051093 201 0.031
small gtpase mediated signal transduction GO:0007264 88 0.030
catabolic process GO:0009056 409 0.030
regulation of protein metabolic process GO:0051246 256 0.029
gene silencing GO:0016458 138 0.029
immune response activating signal transduction GO:0002757 2 0.029
growth GO:0040007 359 0.029
pigment metabolic process GO:0042440 84 0.028
organic substance catabolic process GO:1901575 308 0.028
response to lipopolysaccharide GO:0032496 4 0.028
germ line stem cell maintenance GO:0030718 50 0.028
regulation of autophagy GO:0010506 62 0.027
regulation of innate immune response GO:0045088 71 0.027
stress activated mapk cascade GO:0051403 52 0.027
pigmentation GO:0043473 75 0.027
Human
positive regulation of biosynthetic process GO:0009891 316 0.027
immune response regulating signaling pathway GO:0002764 2 0.026
regulation of cell differentiation GO:0045595 302 0.026
developmental pigmentation GO:0048066 68 0.026
compound eye development GO:0048749 307 0.026
regulation of response to biotic stimulus GO:0002831 63 0.026
response to temperature stimulus GO:0009266 106 0.026
regulation of immune response GO:0050776 118 0.026
digestive tract morphogenesis GO:0048546 127 0.026
positive regulation of catalytic activity GO:0043085 118 0.026
regulation of cuticle pigmentation GO:0048079 16 0.026
eye development GO:0001654 323 0.026
regulation of anatomical structure morphogenesis GO:0022603 242 0.025
response to starvation GO:0042594 97 0.025
positive regulation of molecular function GO:0044093 136 0.025
regulation of small gtpase mediated signal transduction GO:0051056 93 0.025
positive regulation of phosphate metabolic process GO:0045937 139 0.025
molting cycle process GO:0022404 29 0.025
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.025
regulation of cell cycle process GO:0010564 181 0.025
translation GO:0006412 69 0.025
epithelial cell differentiation GO:0030855 322 0.025
signal transduction by phosphorylation GO:0023014 107 0.024
autophagy GO:0006914 108 0.024
compound eye morphogenesis GO:0001745 249 0.024
protein complex biogenesis GO:0070271 201 0.024
single organism biosynthetic process GO:0044711 206 0.024
vesicle fusion GO:0006906 19 0.024
wnt signaling pathway GO:0016055 98 0.024
cellular response to chemical stimulus GO:0070887 199 0.024
positive regulation of intracellular signal transduction GO:1902533 116 0.023
regulation of phosphorylation GO:0042325 147 0.023
cellular response to external stimulus GO:0071496 66 0.023
small molecule metabolic process GO:0044281 305 0.023
regulation of response to external stimulus GO:0032101 115 0.023
negative regulation of peptidoglycan recognition protein signaling pathway GO:0061060 3 0.022
organonitrogen compound metabolic process GO:1901564 318 0.022
developmental maturation GO:0021700 172 0.022
posttranscriptional regulation of gene expression GO:0010608 145 0.022
dendrite development GO:0016358 204 0.021
asymmetric stem cell division GO:0098722 49 0.021
nuclear division GO:0000280 332 0.021
developmental programmed cell death GO:0010623 138 0.021
positive regulation of defense response GO:0031349 59 0.021
heterochromatin organization GO:0070828 25 0.021
vacuolar transport GO:0007034 13 0.020
regulation of immune effector process GO:0002697 52 0.020
positive regulation of multicellular organismal process GO:0051240 143 0.020
protein complex assembly GO:0006461 200 0.020
antimicrobial peptide production GO:0002775 46 0.020
synaptic transmission GO:0007268 288 0.020
organonitrogen compound biosynthetic process GO:1901566 117 0.020
cell fate determination GO:0001709 91 0.020
single organism membrane organization GO:0044802 93 0.020
regulation of cellular component biogenesis GO:0044087 201 0.019
regulation of peptidoglycan recognition protein signaling pathway GO:0061058 4 0.019
regulation of apoptotic process GO:0042981 130 0.019
intracellular protein transport GO:0006886 104 0.019
homeostatic process GO:0042592 199 0.019
lysosome organization GO:0007040 4 0.019
regulation of cellular catabolic process GO:0031329 157 0.019
cell cycle checkpoint GO:0000075 95 0.019
apoptotic process GO:0006915 159 0.019
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.018
forebrain development GO:0030900 2 0.018
single organism catabolic process GO:0044712 228 0.018
connective tissue development GO:0061448 3 0.018
response to alcohol GO:0097305 95 0.018
eye morphogenesis GO:0048592 260 0.018
positive regulation of cell migration GO:0030335 2 0.018
regulation of catabolic process GO:0009894 170 0.018
negative regulation of cell differentiation GO:0045596 143 0.018
dorsal ventral pattern formation GO:0009953 133 0.018
cellular amide metabolic process GO:0043603 80 0.018
secondary metabolic process GO:0019748 75 0.018
macromolecule catabolic process GO:0009057 161 0.018
molting cycle chitin based cuticle GO:0007591 56 0.018
cell cycle arrest GO:0007050 4 0.018
response to heat GO:0009408 63 0.018
jnk cascade GO:0007254 50 0.017
regulation of wnt signaling pathway GO:0030111 68 0.017
ras protein signal transduction GO:0007265 88 0.017
positive regulation of apoptotic process GO:0043065 47 0.017
tissue morphogenesis GO:0048729 297 0.017
regulation of stress activated mapk cascade GO:0032872 41 0.017
stem cell differentiation GO:0048863 117 0.017
neuron projection guidance GO:0097485 241 0.017
camera type eye development GO:0043010 4 0.017
kidney morphogenesis GO:0060993 3 0.017
dna damage checkpoint GO:0000077 78 0.017
chemotaxis GO:0006935 249 0.016
positive regulation of cellular component biogenesis GO:0044089 80 0.016
body morphogenesis GO:0010171 2 0.016
cellularization GO:0007349 90 0.016
regulation of immune system process GO:0002682 176 0.016
toll signaling pathway GO:0008063 25 0.016
cell cell signaling involved in cell fate commitment GO:0045168 210 0.016
carbohydrate metabolic process GO:0005975 82 0.016
response to fungus GO:0009620 50 0.016
regulation of cell death GO:0010941 173 0.016
regulation of transport GO:0051049 181 0.016
necrotic cell death GO:0070265 1 0.016
regulation of cell proliferation GO:0042127 163 0.016
positive regulation of hydrolase activity GO:0051345 78 0.016
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.016
chromosome organization GO:0051276 360 0.016
negative regulation of wnt signaling pathway GO:0030178 28 0.016
stress activated protein kinase signaling cascade GO:0031098 55 0.016
response to organophosphorus GO:0046683 2 0.016
digestive system development GO:0055123 149 0.016
detection of stimulus GO:0051606 156 0.016
cellular response to organic substance GO:0071310 132 0.016
oxoacid metabolic process GO:0043436 103 0.016
digestive tract development GO:0048565 149 0.015
positive regulation of phosphorus metabolic process GO:0010562 139 0.015
melanization defense response GO:0035006 45 0.015
anatomical structure homeostasis GO:0060249 97 0.015
regulation of humoral immune response GO:0002920 51 0.015
antimicrobial peptide biosynthetic process GO:0002777 38 0.015
muscle structure development GO:0061061 224 0.015
regulation of localization GO:0032879 275 0.015
regulation of developmental pigmentation GO:0048070 24 0.015
oocyte differentiation GO:0009994 145 0.015
regulation of defense response to bacterium GO:1900424 30 0.015
rna processing GO:0006396 147 0.015
cell migration GO:0016477 238 0.015
carboxylic acid metabolic process GO:0019752 92 0.014
signal transduction in response to dna damage GO:0042770 3 0.014
regulation of cellular amine metabolic process GO:0033238 3 0.014
macromolecular complex assembly GO:0065003 256 0.014
cell growth GO:0016049 108 0.014
muscle organ development GO:0007517 127 0.014
myotube cell development GO:0014904 3 0.014
regulation of notch signaling pathway GO:0008593 100 0.014
taxis GO:0042330 304 0.014
nitrogen compound transport GO:0071705 85 0.014
skeletal muscle fiber development GO:0048741 3 0.014
regulation of translation GO:0006417 56 0.014
oxidoreduction coenzyme metabolic process GO:0006733 2 0.014
sensory organ morphogenesis GO:0090596 260 0.014
regulation of mitotic cell cycle GO:0007346 190 0.014
compound eye photoreceptor development GO:0042051 78 0.014
negative regulation of multicellular organismal process GO:0051241 142 0.014
positive regulation of phosphorylation GO:0042327 87 0.014
regulation of cellular response to stress GO:0080135 89 0.014
somatic muscle development GO:0007525 66 0.014
positive regulation of cellular protein metabolic process GO:0032270 118 0.014
extrinsic apoptotic signaling pathway GO:0097191 1 0.014
regulation of developmental growth GO:0048638 174 0.014
regulation of hydrolase activity GO:0051336 97 0.013
xenobiotic catabolic process GO:0042178 1 0.013
regulation of rna splicing GO:0043484 69 0.013
positive regulation of cell size GO:0045793 21 0.013
embryonic morphogenesis GO:0048598 206 0.013
organic acid metabolic process GO:0006082 103 0.013
telencephalon development GO:0021537 2 0.013
female meiotic division GO:0007143 70 0.013
regulation of multicellular organismal development GO:2000026 414 0.013
negative regulation of intracellular signal transduction GO:1902532 57 0.013
carbohydrate derivative metabolic process GO:1901135 217 0.013
negative regulation of programmed cell death GO:0043069 72 0.013
regulation of production of molecular mediator of immune response GO:0002700 44 0.013
positive regulation of apoptotic signaling pathway GO:2001235 4 0.013
cuticle development GO:0042335 86 0.013
biosynthetic process of antibacterial peptides active against gram negative bacteria GO:0002812 14 0.013
positive regulation of cell death GO:0010942 69 0.013
response to organic cyclic compound GO:0014070 89 0.013
regulation of adult chitin containing cuticle pigmentation GO:0048082 13 0.013
dna metabolic process GO:0006259 227 0.013
regulation of gene expression epigenetic GO:0040029 128 0.013
positive regulation of cell motility GO:2000147 3 0.013
male gamete generation GO:0048232 201 0.013
open tracheal system development GO:0007424 204 0.013
rna localization GO:0006403 115 0.013
positive regulation of protein metabolic process GO:0051247 128 0.013
meiotic nuclear division GO:0007126 151 0.013
regulation of synapse structure and activity GO:0050803 128 0.013
determination of adult lifespan GO:0008340 137 0.013
negative regulation of phosphorylation GO:0042326 35 0.013
positive regulation of cellular component organization GO:0051130 156 0.012
retina development in camera type eye GO:0060041 4 0.012
trna modification GO:0006400 2 0.012
chitin based cuticle sclerotization GO:0007593 19 0.012
cellular response to molecule of bacterial origin GO:0071219 3 0.012
cellular amine metabolic process GO:0044106 12 0.012
gastrulation GO:0007369 70 0.012
lateral inhibition GO:0046331 206 0.012
cellular response to lipopolysaccharide GO:0071222 3 0.012
regulation of cellular amide metabolic process GO:0034248 39 0.012
neural retina development GO:0003407 4 0.012
negative regulation of protein metabolic process GO:0051248 85 0.012
nephron tubule development GO:0072080 3 0.012
nucleoside phosphate metabolic process GO:0006753 162 0.012
detection of mechanical stimulus involved in sensory perception of pain GO:0050966 2 0.012
purine nucleotide catabolic process GO:0006195 109 0.012
regulation of jnk cascade GO:0046328 40 0.012
meiotic cell cycle GO:0051321 171 0.012
regulation of mrna processing GO:0050684 71 0.012
localization of cell GO:0051674 257 0.012
regulation of antibacterial peptide production GO:0002786 22 0.012
cellular response to heat GO:0034605 24 0.012
vitamin metabolic process GO:0006766 2 0.012
regulation of protein modification process GO:0031399 112 0.012
positive regulation of immune response GO:0050778 63 0.012
regulation of ras protein signal transduction GO:0046578 93 0.012
regulation of antimicrobial peptide production GO:0002784 44 0.012
dendrite morphogenesis GO:0048813 199 0.012
nephron epithelium development GO:0072009 3 0.012
gland development GO:0048732 191 0.011
photoreceptor cell development GO:0042461 96 0.011
positive regulation of mapk cascade GO:0043410 63 0.011
response to hypoxia GO:0001666 53 0.011
nucleotide metabolic process GO:0009117 161 0.011
cell aging GO:0007569 2 0.011
regulation of transferase activity GO:0051338 58 0.011
biosynthetic process of antibacterial peptides active against gram positive bacteria GO:0002815 3 0.011
eye photoreceptor cell development GO:0042462 81 0.011
response to copper ion GO:0046688 4 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.011
gastrulation involving germ band extension GO:0010004 36 0.011
negative regulation of cellular protein metabolic process GO:0032269 85 0.011
proteolysis GO:0006508 192 0.011
regulation of antimicrobial peptide biosynthetic process GO:0002805 38 0.011
chaeta development GO:0022416 97 0.011
positive regulation of immune system process GO:0002684 68 0.011
stem cell maintenance GO:0019827 67 0.011
chromatin remodeling GO:0006338 72 0.011
negative regulation of cell cycle GO:0045786 116 0.011
cellular response to biotic stimulus GO:0071216 4 0.011
stem cell division GO:0017145 69 0.011
response to oxygen levels GO:0070482 59 0.011
single organism behavior GO:0044708 391 0.011
regulation of cell size GO:0008361 63 0.011
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.011
cuticle pigmentation GO:0048067 22 0.011
establishment or maintenance of cell polarity GO:0007163 167 0.011
regulation of nervous system development GO:0051960 248 0.011
regulation of chitin based cuticle tanning GO:0007564 14 0.011
regulation of antibacterial peptide biosynthetic process GO:0002808 22 0.011
kidney epithelium development GO:0072073 3 0.011
cellular nitrogen compound catabolic process GO:0044270 165 0.011
adult chitin containing cuticle pigmentation GO:0048085 16 0.010
response to nitrogen compound GO:1901698 90 0.010
negative regulation of cell death GO:0060548 81 0.010
cellular amino acid metabolic process GO:0006520 61 0.010
cell cycle phase transition GO:0044770 140 0.010
response to monosaccharide GO:0034284 4 0.010
positive regulation of protein kinase activity GO:0045860 25 0.010
aging GO:0007568 143 0.010
salivary gland development GO:0007431 162 0.010
vitamin biosynthetic process GO:0009110 1 0.010
regulation of mrna metabolic process GO:1903311 72 0.010
positive regulation of nucleoside metabolic process GO:0045979 47 0.010
histone modification GO:0016570 106 0.010
nucleobase containing small molecule metabolic process GO:0055086 174 0.010
positive regulation of protein modification process GO:0031401 58 0.010
antibacterial peptide biosynthetic process GO:0002780 22 0.010
morphogenesis of an epithelium GO:0002009 276 0.010
regulation of organelle organization GO:0033043 196 0.010
kidney development GO:0001822 3 0.010
trna processing GO:0008033 3 0.010
response to endogenous stimulus GO:0009719 119 0.010
regulation of cellular localization GO:0060341 136 0.010
autophagic vacuole assembly GO:0000045 2 0.010
cellular macromolecular complex assembly GO:0034622 153 0.010
gastrulation with mouth forming first GO:0001703 36 0.010

Vps33B disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.037
disease of cellular proliferation DOID:14566 0 0.015
disease of metabolism DOID:0014667 0 0.013
inherited metabolic disorder DOID:655 0 0.013
cancer DOID:162 0 0.010
organ system cancer DOID:0050686 0 0.010