Drosophila melanogaster

79 known processes

Cdk9 (Dmel_CG5179)

Cyclin-dependent kinase 9

(Aliases: P-TEFb,CG5179,P-TEF,Dmel\CG5179,PTefb,cdk9,CDK9)

Cdk9 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of biosynthetic process GO:0009890 277 0.706
Human
transcription from rna polymerase ii promoter GO:0006366 368 0.479
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.440
Human
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.293
Human
negative regulation of rna biosynthetic process GO:1902679 240 0.286
positive regulation of macromolecule metabolic process GO:0010604 405 0.277
Yeast
negative regulation of transcription dna templated GO:0045892 237 0.245
negative regulation of rna metabolic process GO:0051253 251 0.195
nuclear division GO:0000280 332 0.194
negative regulation of signaling GO:0023057 219 0.183
negative regulation of cellular metabolic process GO:0031324 382 0.159
Human
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.127
Yeast
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.123
negative regulation of cellular biosynthetic process GO:0031327 277 0.113
Human
intracellular signal transduction GO:0035556 300 0.108
chromosome organization GO:0051276 360 0.107
Human Yeast
positive regulation of rna biosynthetic process GO:1902680 266 0.104
negative regulation of cell communication GO:0010648 223 0.102
regulation of gene expression epigenetic GO:0040029 128 0.097
mrna processing GO:0006397 104 0.092
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.089
Human
ras protein signal transduction GO:0007265 88 0.088
negative regulation of signal transduction GO:0009968 206 0.086
positive regulation of transcription dna templated GO:0045893 266 0.082
phosphorylation GO:0016310 294 0.080
regulation of intracellular signal transduction GO:1902531 236 0.079
cell death GO:0008219 279 0.078
regulation of cell cycle GO:0051726 291 0.076
organelle fission GO:0048285 340 0.076
negative regulation of response to stimulus GO:0048585 258 0.074
regulation of protein metabolic process GO:0051246 256 0.072
Human Yeast
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.071
Human
rna processing GO:0006396 147 0.063
small gtpase mediated signal transduction GO:0007264 88 0.063
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.063
positive regulation of nucleic acid templated transcription GO:1903508 266 0.060
regionalization GO:0003002 416 0.059
negative regulation of gene expression GO:0010629 387 0.058
positive regulation of signaling GO:0023056 243 0.055
axis specification GO:0009798 167 0.054
positive regulation of cellular biosynthetic process GO:0031328 316 0.053
meiotic dna double strand break formation involved in reciprocal meiotic recombination GO:0010780 1 0.052
negative regulation of nucleic acid templated transcription GO:1903507 240 0.048
positive regulation of signal transduction GO:0009967 223 0.048
death GO:0016265 284 0.048
macromolecular complex assembly GO:0065003 256 0.046
regulation of cellular protein metabolic process GO:0032268 243 0.046
Human Yeast
regulation of ras protein signal transduction GO:0046578 93 0.045
regulation of cell cycle process GO:0010564 181 0.042
Human
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.042
mapk cascade GO:0000165 107 0.041
positive regulation of gene expression GO:0010628 290 0.039
organic substance catabolic process GO:1901575 308 0.038
positive regulation of rna metabolic process GO:0051254 271 0.038
regulation of cell death GO:0010941 173 0.038
meiotic dna double strand break formation GO:0042138 1 0.038
imaginal disc derived wing morphogenesis GO:0007476 337 0.037
positive regulation of response to stimulus GO:0048584 323 0.037
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.037
embryonic axis specification GO:0000578 107 0.037
regulation of apoptotic process GO:0042981 130 0.036
negative regulation of developmental process GO:0051093 201 0.036
regulation of phosphate metabolic process GO:0019220 210 0.035
mrna metabolic process GO:0016071 124 0.034
germarium derived egg chamber formation GO:0007293 101 0.034
regulation of programmed cell death GO:0043067 152 0.034
anterior posterior axis specification GO:0009948 109 0.031
regulation of small gtpase mediated signal transduction GO:0051056 93 0.031
regulation of mapk cascade GO:0043408 92 0.031
apoptotic process GO:0006915 159 0.030
programmed cell death GO:0012501 257 0.030
regulation of mitotic cell cycle GO:0007346 190 0.030
positive regulation of erk1 and erk2 cascade GO:0070374 36 0.029
negative regulation of cell cycle GO:0045786 116 0.027
Human
mrna splicing via spliceosome GO:0000398 73 0.027
cell proliferation GO:0008283 299 0.027
developmental maturation GO:0021700 172 0.026
positive regulation of cell communication GO:0010647 250 0.026
chromatin remodeling GO:0006338 72 0.025
positive regulation of biosynthetic process GO:0009891 316 0.025
mitotic cell cycle phase transition GO:0044772 138 0.025
cell cycle checkpoint GO:0000075 95 0.025
extrinsic apoptotic signaling pathway GO:0097191 1 0.024
locomotory behavior GO:0007626 176 0.024
cellular protein modification process GO:0006464 438 0.024
regulation of multicellular organismal development GO:2000026 414 0.024
signal transduction by phosphorylation GO:0023014 107 0.023
carbohydrate derivative metabolic process GO:1901135 217 0.023
cell migration GO:0016477 238 0.023
negative regulation of wnt signaling pathway GO:0030178 28 0.023
regulation of anatomical structure morphogenesis GO:0022603 242 0.023
gene silencing GO:0016458 138 0.023
actin cytoskeleton organization GO:0030036 206 0.022
positive regulation of cellular protein metabolic process GO:0032270 118 0.022
Yeast
immune system process GO:0002376 347 0.022
mitotic nuclear division GO:0007067 213 0.022
positive regulation of programmed cell death GO:0043068 62 0.022
cellular response to dna damage stimulus GO:0006974 223 0.022
Human
cell cycle phase transition GO:0044770 140 0.022
positive regulation of cell death GO:0010942 69 0.022
tripartite regional subdivision GO:0007351 103 0.022
regulation of localization GO:0032879 275 0.021
negative regulation of protein metabolic process GO:0051248 85 0.021
regulation of response to external stimulus GO:0032101 115 0.021
rna splicing via transesterification reactions GO:0000375 73 0.021
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.021
positive regulation of ras protein signal transduction GO:0046579 43 0.021
rna localization GO:0006403 115 0.021
rna splicing GO:0008380 83 0.020
regulation of immune system process GO:0002682 176 0.020
meiotic cell cycle GO:0051321 171 0.020
positive regulation of apoptotic signaling pathway GO:2001235 4 0.020
multi organism behavior GO:0051705 175 0.020
cell motility GO:0048870 251 0.020
chromatin modification GO:0016568 147 0.019
Human Yeast
localization of cell GO:0051674 257 0.019
single organism behavior GO:0044708 391 0.019
protein modification process GO:0036211 438 0.019
epithelial cell development GO:0002064 274 0.018
spindle elongation GO:0051231 83 0.018
anterior posterior axis specification embryo GO:0008595 103 0.018
positive regulation of cellular component biogenesis GO:0044089 80 0.017
regulation of molecular function GO:0065009 217 0.017
endocytosis GO:0006897 310 0.017
post embryonic appendage morphogenesis GO:0035120 385 0.017
organic substance transport GO:0071702 257 0.017
vesicle mediated transport GO:0016192 381 0.017
regulation of multi organism process GO:0043900 131 0.017
appendage development GO:0048736 401 0.017
cellular macromolecule catabolic process GO:0044265 136 0.016
regulation of cell shape GO:0008360 113 0.016
covalent chromatin modification GO:0016569 106 0.016
Human Yeast
cell division GO:0051301 248 0.016
histone modification GO:0016570 106 0.016
Human Yeast
regulation of phosphorus metabolic process GO:0051174 210 0.015
negative regulation of mitotic cell cycle GO:0045930 109 0.015
establishment of localization in cell GO:0051649 402 0.015
regulation of cellular localization GO:0060341 136 0.015
cytoplasmic transport GO:0016482 130 0.015
regulation of cell differentiation GO:0045595 302 0.015
negative regulation of cell differentiation GO:0045596 143 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
organonitrogen compound metabolic process GO:1901564 318 0.015
response to bacterium GO:0009617 198 0.015
regulation of cell development GO:0060284 215 0.014
protein dna complex subunit organization GO:0071824 86 0.014
establishment of rna localization GO:0051236 47 0.014
ovarian follicle cell development GO:0030707 248 0.014
intracellular transport GO:0046907 228 0.014
negative regulation of gene expression epigenetic GO:0045814 77 0.014
anatomical structure homeostasis GO:0060249 97 0.013
regulation of response to stress GO:0080134 200 0.013
Human
cellular response to radiation GO:0071478 52 0.013
mitotic g2 dna damage checkpoint GO:0007095 69 0.013
mitotic spindle organization GO:0007052 220 0.013
transcription initiation from rna polymerase ii promoter GO:0006367 25 0.013
positive regulation of phosphorylation GO:0042327 87 0.013
axon development GO:0061564 297 0.013
protein phosphorylation GO:0006468 169 0.013
chemotaxis GO:0006935 249 0.013
response to radiation GO:0009314 155 0.013
apoptotic signaling pathway GO:0097190 27 0.013
synaptic transmission GO:0007268 288 0.012
mitotic cell cycle checkpoint GO:0007093 88 0.012
neuron projection guidance GO:0097485 241 0.012
ocellus pigmentation GO:0033060 19 0.012
positive regulation of phosphate metabolic process GO:0045937 139 0.012
organelle assembly GO:0070925 198 0.012
regulation of cell morphogenesis GO:0022604 163 0.012
mitotic g2 m transition checkpoint GO:0044818 70 0.012
purine ribonucleotide metabolic process GO:0009150 145 0.012
positive regulation of phosphorus metabolic process GO:0010562 139 0.012
taxis GO:0042330 304 0.012
heterocycle catabolic process GO:0046700 166 0.012
regulation of erbb signaling pathway GO:1901184 42 0.012
regulation of meiosis GO:0040020 3 0.012
imaginal disc derived appendage development GO:0048737 399 0.012
heterochromatin organization GO:0070828 25 0.012
regulation of translation GO:0006417 56 0.012
regulation of wnt signaling pathway GO:0030111 68 0.012
appendage morphogenesis GO:0035107 397 0.012
defense response GO:0006952 300 0.012
embryonic pattern specification GO:0009880 174 0.011
homeostatic process GO:0042592 199 0.011
nucleobase containing compound transport GO:0015931 56 0.011
regulation of mitotic cell cycle phase transition GO:1901990 130 0.011
negative regulation of programmed cell death GO:0043069 72 0.011
phagocytosis GO:0006909 215 0.011
catabolic process GO:0009056 409 0.011
oocyte differentiation GO:0009994 145 0.011
protein acylation GO:0043543 42 0.011
wing disc morphogenesis GO:0007472 344 0.011
organic cyclic compound catabolic process GO:1901361 168 0.011
posttranscriptional regulation of gene expression GO:0010608 145 0.011
positive regulation of cellular component organization GO:0051130 156 0.011
Yeast
cell maturation GO:0048469 144 0.011
protein complex biogenesis GO:0070271 201 0.011
reproductive structure development GO:0048608 74 0.011
erk1 and erk2 cascade GO:0070371 39 0.011
regulation of organelle organization GO:0033043 196 0.011
Human Yeast
spindle organization GO:0007051 253 0.011
regulation of mrna metabolic process GO:1903311 72 0.011
negative regulation of cell death GO:0060548 81 0.011
mrna 3 end processing GO:0031124 28 0.011
aromatic compound catabolic process GO:0019439 166 0.011
negative regulation of apoptotic process GO:0043066 63 0.010
regulation of nuclear division GO:0051783 58 0.010
rna transport GO:0050658 46 0.010
nucleotide metabolic process GO:0009117 161 0.010
mitotic dna integrity checkpoint GO:0044774 75 0.010
reproductive behavior GO:0019098 122 0.010
positive regulation of apoptotic process GO:0043065 47 0.010
regulation of phosphorylation GO:0042325 147 0.010
dna metabolic process GO:0006259 227 0.010
Human

Cdk9 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.016