Drosophila melanogaster

48 known processes

bon (Dmel_CG5206)

bonus

(Aliases: 150269_at,anon-WO0118547.418,0241/08,CG5206,Bonus,l(3)S043420,150268_at,0249/12,CG15687,Bon,Dmel\CG5206,0434/20,0487/06)

bon biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein modification by small protein conjugation or removal GO:0070647 106 0.733
Human Mouse
synapse organization GO:0050808 196 0.693
cellular protein modification process GO:0006464 438 0.663
Human Mouse
chromatin organization GO:0006325 207 0.540
dna metabolic process GO:0006259 227 0.504
Human Mouse
protein modification by small protein conjugation GO:0032446 79 0.479
Human Mouse
protein ubiquitination GO:0016567 70 0.424
Human Mouse
chromosome organization GO:0051276 360 0.396
photoreceptor cell differentiation GO:0046530 170 0.385
regulation of cell death GO:0010941 173 0.335
Human
regulation of catalytic activity GO:0050790 185 0.310
protein acetylation GO:0006473 39 0.299
protein modification process GO:0036211 438 0.298
Human Mouse
transcription from rna polymerase ii promoter GO:0006366 368 0.284
Zebrafish Mouse
regulation of gene expression epigenetic GO:0040029 128 0.282
Mouse
internal peptidyl lysine acetylation GO:0018393 38 0.262
gene silencing GO:0016458 138 0.248
positive regulation of macromolecule metabolic process GO:0010604 405 0.245
Human Mouse
regulation of protein metabolic process GO:0051246 256 0.241
appendage morphogenesis GO:0035107 397 0.225
carbohydrate derivative metabolic process GO:1901135 217 0.221
nucleocytoplasmic transport GO:0006913 72 0.199
Human
trachea development GO:0060438 29 0.198
post embryonic appendage morphogenesis GO:0035120 385 0.193
taxis GO:0042330 304 0.189
imaginal disc derived appendage development GO:0048737 399 0.188
negative regulation of cell communication GO:0010648 223 0.185
Human
positive regulation of endopeptidase activity GO:0010950 26 0.183
growth GO:0040007 359 0.170
Mouse
regulation of molecular function GO:0065009 217 0.167
negative regulation of gene expression GO:0010629 387 0.167
Human Mouse
intracellular transport GO:0046907 228 0.155
Human
regulation of cell cycle process GO:0010564 181 0.148
imaginal disc derived appendage morphogenesis GO:0035114 395 0.134
chromatin remodeling GO:0006338 72 0.133
chromatin modification GO:0016568 147 0.130
protein acylation GO:0043543 42 0.125
regulation of synapse organization GO:0050807 110 0.119
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.117
Human Mouse
larval midgut histolysis GO:0035069 22 0.117
peptidyl lysine modification GO:0018205 57 0.114
positive regulation of cellular biosynthetic process GO:0031328 316 0.114
Mouse
extracellular structure organization GO:0043062 46 0.112
purine nucleotide metabolic process GO:0006163 146 0.106
positive regulation of catalytic activity GO:0043085 118 0.104
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.104
nuclear division GO:0000280 332 0.097
eye development GO:0001654 323 0.097
catabolic process GO:0009056 409 0.095
Human Mouse
negative regulation of response to stimulus GO:0048585 258 0.095
Human
positive regulation of proteolysis GO:0045862 52 0.092
protein catabolic process GO:0030163 101 0.091
Human Mouse
positive regulation of molecular function GO:0044093 136 0.090
extracellular matrix organization GO:0030198 32 0.089
compound eye photoreceptor cell differentiation GO:0001751 140 0.088
cardiovascular system development GO:0072358 82 0.087
regulation of mitotic cell cycle GO:0007346 190 0.084
regionalization GO:0003002 416 0.084
eye morphogenesis GO:0048592 260 0.084
histone acetylation GO:0016573 38 0.077
endocytosis GO:0006897 310 0.077
negative regulation of programmed cell death GO:0043069 72 0.075
chromatin silencing GO:0006342 76 0.074
organelle localization GO:0051640 148 0.072
regulation of gene silencing GO:0060968 63 0.072
cellular catabolic process GO:0044248 372 0.071
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.070
Human Mouse
tissue death GO:0016271 102 0.069
eggshell formation GO:0030703 105 0.068
negative regulation of signaling GO:0023057 219 0.065
Human
dendrite morphogenesis GO:0048813 199 0.065
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.065
Human Mouse
columnar cuboidal epithelial cell development GO:0002066 249 0.064
proteolysis GO:0006508 192 0.064
regulation of programmed cell death GO:0043067 152 0.062
Human
nucleoside phosphate catabolic process GO:1901292 110 0.061
vesicle mediated transport GO:0016192 381 0.060
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.059
cell proliferation GO:0008283 299 0.056
Mouse
appendage development GO:0048736 401 0.054
Zebrafish
reproductive system development GO:0061458 74 0.053
Mouse
notch receptor processing GO:0007220 13 0.053
positive regulation of cellular component biogenesis GO:0044089 80 0.052
imaginal disc derived wing morphogenesis GO:0007476 337 0.050
circulatory system development GO:0072359 82 0.049
regulation of phosphatase activity GO:0010921 3 0.049
telencephalon development GO:0021537 2 0.047
programmed cell death GO:0012501 257 0.047
Human
neuron projection guidance GO:0097485 241 0.046
regulation of cell cycle GO:0051726 291 0.045
synapse assembly GO:0007416 143 0.044
negative regulation of cell death GO:0060548 81 0.044
covalent chromatin modification GO:0016569 106 0.043
morphogenesis of a branching epithelium GO:0061138 45 0.043
organic substance catabolic process GO:1901575 308 0.041
Human Mouse
larval development GO:0002164 104 0.041
regulation of cellular protein metabolic process GO:0032268 243 0.041
induction of programmed cell death by hormones GO:0035081 12 0.041
r7 cell differentiation GO:0045466 43 0.040
embryo development ending in birth or egg hatching GO:0009792 152 0.040
Mouse
tissue morphogenesis GO:0048729 297 0.040
Mouse
connective tissue development GO:0061448 3 0.038
gene silencing by rna GO:0031047 57 0.038
internal protein amino acid acetylation GO:0006475 38 0.037
respiratory system development GO:0060541 213 0.037
protein maturation GO:0051604 71 0.037
posttranscriptional regulation of gene expression GO:0010608 145 0.035
Human Mouse
nucleobase containing small molecule metabolic process GO:0055086 174 0.035
positive regulation of nucleic acid templated transcription GO:1903508 266 0.035
Mouse
purine ribonucleoside metabolic process GO:0046128 127 0.034
positive regulation of protein metabolic process GO:0051247 128 0.034
regulation of phosphate metabolic process GO:0019220 210 0.034
regulation of response to dna damage stimulus GO:2001020 23 0.034
Human
cell death GO:0008219 279 0.034
Human
dosage compensation GO:0007549 16 0.034
histone h4 k16 acetylation GO:0043984 4 0.034
compound eye photoreceptor development GO:0042051 78 0.033
small molecule metabolic process GO:0044281 305 0.033
peptidyl amino acid modification GO:0018193 105 0.033
cell division GO:0051301 248 0.033
induction of programmed cell death by ecdysone GO:0035078 12 0.032
spermatogenesis GO:0007283 200 0.032
regulation of phosphorus metabolic process GO:0051174 210 0.032
positive regulation of phosphate metabolic process GO:0045937 139 0.032
apoptotic process GO:0006915 159 0.032
Human
receptor clustering GO:0043113 3 0.031
forebrain development GO:0030900 2 0.031
negative regulation of biosynthetic process GO:0009890 277 0.030
Human Mouse
eye photoreceptor cell differentiation GO:0001754 145 0.030
sulfur compound metabolic process GO:0006790 59 0.030
eye photoreceptor cell development GO:0042462 81 0.029
regulation of nervous system development GO:0051960 248 0.029
nucleoside metabolic process GO:0009116 127 0.029
cytoplasmic transport GO:0016482 130 0.029
Human
regulation of imaginal disc growth GO:0045570 26 0.029
hemopoiesis GO:0030097 46 0.028
Zebrafish
carboxylic acid metabolic process GO:0019752 92 0.028
negative regulation of signal transduction GO:0009968 206 0.027
Human
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.027
Human Mouse
compound eye morphogenesis GO:0001745 249 0.027
male gamete generation GO:0048232 201 0.026
positive regulation of multicellular organismal process GO:0051240 143 0.026
open tracheal system development GO:0007424 204 0.025
terminal branching open tracheal system GO:0007430 17 0.025
cell fate specification GO:0001708 71 0.025
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.025
macromolecule catabolic process GO:0009057 161 0.024
Human Mouse
purine ribonucleoside catabolic process GO:0046130 112 0.024
brain development GO:0007420 120 0.024
spindle organization GO:0007051 253 0.024
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.024
nucleoside triphosphate catabolic process GO:0009143 108 0.024
regulation of cellular response to stress GO:0080135 89 0.024
Human
single organism behavior GO:0044708 391 0.023
positive regulation of peptidase activity GO:0010952 29 0.023
peptidyl lysine methylation GO:0018022 16 0.023
carbohydrate derivative biosynthetic process GO:1901137 85 0.023
ion homeostasis GO:0050801 55 0.023
Mouse
single organism biosynthetic process GO:0044711 206 0.022
macromolecular complex assembly GO:0065003 256 0.022
Human
purine nucleoside triphosphate catabolic process GO:0009146 108 0.022
mitotic nuclear division GO:0007067 213 0.022
negative regulation of rna metabolic process GO:0051253 251 0.022
Human Mouse
sex differentiation GO:0007548 81 0.021
death GO:0016265 284 0.021
Human
pigmentation GO:0043473 75 0.021
synaptic vesicle localization GO:0097479 53 0.020
positive regulation of rna metabolic process GO:0051254 271 0.020
Mouse
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.020
Mouse
ribonucleoside metabolic process GO:0009119 127 0.020
regulation of notch signaling pathway GO:0008593 100 0.020
segment polarity determination GO:0007367 25 0.020
ribose phosphate metabolic process GO:0019693 145 0.020
regulation of chromatin silencing GO:0031935 36 0.019
posttranscriptional gene silencing GO:0016441 46 0.019
imaginal disc growth GO:0007446 37 0.019
ribonucleoside triphosphate metabolic process GO:0009199 119 0.019
periodic partitioning GO:0007365 29 0.019
nucleoside triphosphate metabolic process GO:0009141 120 0.019
negative regulation of fibroblast growth factor receptor signaling pathway GO:0040037 2 0.019
positive regulation of hydrolase activity GO:0051345 78 0.019
negative regulation of cell differentiation GO:0045596 143 0.018
response to extracellular stimulus GO:0009991 116 0.018
Mouse
organophosphate metabolic process GO:0019637 195 0.018
axonogenesis GO:0007409 290 0.018
regulation of cellular response to hypoxia GO:1900037 3 0.018
regulation of multicellular organism growth GO:0040014 40 0.018
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.017
regulation of purine nucleotide metabolic process GO:1900542 62 0.017
positive regulation of phosphorus metabolic process GO:0010562 139 0.017
negative regulation of catalytic activity GO:0043086 42 0.017
small molecule biosynthetic process GO:0044283 37 0.017
regulation of synapse structure and activity GO:0050803 128 0.017
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.017
Human Mouse
regulation of organelle organization GO:0033043 196 0.017
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.017
Human Zebrafish Mouse
nucleoside phosphate metabolic process GO:0006753 162 0.017
cellular amino acid metabolic process GO:0006520 61 0.016
negative regulation of apoptotic process GO:0043066 63 0.016
regulation of cellular amino acid metabolic process GO:0006521 0 0.016
endosomal transport GO:0016197 44 0.016
regulation of nucleotide metabolic process GO:0006140 62 0.016
response to biotic stimulus GO:0009607 294 0.016
homeostatic process GO:0042592 199 0.016
Zebrafish Mouse
ecdysone mediated induction of salivary gland cell autophagic cell death GO:0035072 12 0.015
central nervous system development GO:0007417 201 0.015
mitochondrial membrane organization GO:0007006 3 0.015
purine ribonucleotide metabolic process GO:0009150 145 0.015
peptidyl lysine trimethylation GO:0018023 6 0.015
negative regulation of chromatin silencing GO:0031936 9 0.015
digestive system development GO:0055123 149 0.015
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.015
regulation of cellular amine metabolic process GO:0033238 3 0.015
amine metabolic process GO:0009308 12 0.015
regulation of cysteine type endopeptidase activity GO:2000116 27 0.015
ribonucleoside triphosphate catabolic process GO:0009203 108 0.015
regulation of endopeptidase activity GO:0052548 36 0.015
regulation of epithelial cell proliferation GO:0050678 4 0.015
positive regulation of gene expression GO:0010628 290 0.015
Mouse
reproductive structure development GO:0048608 74 0.014
Mouse
chemotaxis GO:0006935 249 0.014
regulation of eye photoreceptor cell development GO:0042478 13 0.014
cellular protein catabolic process GO:0044257 83 0.014
cellular response to abiotic stimulus GO:0071214 58 0.014
purine nucleotide catabolic process GO:0006195 109 0.014
organ growth GO:0035265 56 0.014
protein localization GO:0008104 284 0.014
Human
negative regulation of wnt signaling pathway GO:0030178 28 0.014
response to organic substance GO:0010033 284 0.013
Human Mouse
purine containing compound metabolic process GO:0072521 155 0.013
establishment of localization in cell GO:0051649 402 0.013
Human
induction of programmed cell death GO:0012502 12 0.013
organic acid metabolic process GO:0006082 103 0.013
rna splicing GO:0008380 83 0.013
epithelial cell development GO:0002064 274 0.013
purine containing compound catabolic process GO:0072523 112 0.013
cellular response to chemical stimulus GO:0070887 199 0.013
Human Mouse
developmental growth involved in morphogenesis GO:0060560 65 0.013
Mouse
multicellular organism growth GO:0035264 46 0.013
nucleotide metabolic process GO:0009117 161 0.012
regulation of cell differentiation GO:0045595 302 0.012
regulation of cell proliferation GO:0042127 163 0.012
Mouse
regulation of ion transport GO:0043269 39 0.012
cellular response to oxygen containing compound GO:1901701 79 0.012
Mouse
positive regulation of developmental growth GO:0048639 62 0.012
digestive tract development GO:0048565 149 0.012
synaptic transmission GO:0007268 288 0.012
positive regulation of gene expression epigenetic GO:0045815 16 0.012
nucleoside catabolic process GO:0009164 112 0.012
exocrine system development GO:0035272 162 0.012
regulation of protein localization GO:0032880 76 0.011
Human
histolysis GO:0007559 102 0.011
heterocycle catabolic process GO:0046700 166 0.011
head development GO:0060322 135 0.011
positive regulation of cellular component organization GO:0051130 156 0.011
nucleobase containing compound catabolic process GO:0034655 165 0.011
lipid metabolic process GO:0006629 121 0.011
regulation of protein ubiquitination GO:0031396 22 0.011
tube morphogenesis GO:0035239 191 0.011
ovarian follicle cell development GO:0030707 248 0.011
trachea morphogenesis GO:0060439 22 0.011
cellular nitrogen compound catabolic process GO:0044270 165 0.011
sensory organ morphogenesis GO:0090596 260 0.011
imaginal disc derived wing margin morphogenesis GO:0008587 41 0.011
regulation of developmental growth GO:0048638 174 0.011
phosphorylation GO:0016310 294 0.011
Mouse
cytoskeleton dependent intracellular transport GO:0030705 44 0.010
regulation of compound eye photoreceptor development GO:0045314 12 0.010
cell activation GO:0001775 9 0.010
golgi vesicle transport GO:0048193 27 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.010
positive regulation of transcription dna templated GO:0045893 266 0.010
Mouse
necrotic cell death GO:0070265 1 0.010
localization of cell GO:0051674 257 0.010
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.010

bon disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.032