Drosophila melanogaster

74 known processes

gnu (Dmel_CG5272)

giant nuclei

(Aliases: CG5272,Dmel\CG5272,Gnu)

gnu biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single fertilization GO:0007338 24 0.792
egg activation GO:0007343 9 0.786
fertilization GO:0009566 26 0.629
establishment of organelle localization GO:0051656 122 0.515
nucleus organization GO:0006997 45 0.321
establishment of localization in cell GO:0051649 402 0.267
transmembrane transport GO:0055085 139 0.235
nucleus localization GO:0051647 34 0.210
meiotic cell cycle GO:0051321 171 0.196
negative regulation of rna biosynthetic process GO:1902679 240 0.195
organelle localization GO:0051640 148 0.171
ion transmembrane transport GO:0034220 122 0.140
dna metabolic process GO:0006259 227 0.126
cellular response to nutrient levels GO:0031669 62 0.126
organonitrogen compound biosynthetic process GO:1901566 117 0.115
regulation of cell differentiation GO:0045595 302 0.112
meiotic chromosome segregation GO:0045132 59 0.112
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.110
nuclear division GO:0000280 332 0.097
chromosome condensation GO:0030261 41 0.097
ion transport GO:0006811 145 0.093
regulation of localization GO:0032879 275 0.089
cellular catabolic process GO:0044248 372 0.089
organelle fusion GO:0048284 46 0.088
protein ubiquitination GO:0016567 70 0.088
organonitrogen compound metabolic process GO:1901564 318 0.085
actin filament based process GO:0030029 220 0.079
response to bacterium GO:0009617 198 0.075
vacuolar transport GO:0007034 13 0.071
single organism biosynthetic process GO:0044711 206 0.070
positive regulation of cellular biosynthetic process GO:0031328 316 0.069
negative regulation of rna metabolic process GO:0051253 251 0.069
response to external biotic stimulus GO:0043207 293 0.066
single organism cellular localization GO:1902580 180 0.064
nuclear migration GO:0007097 20 0.064
response to other organism GO:0051707 293 0.061
negative regulation of transcription dna templated GO:0045892 237 0.061
nucleoside phosphate metabolic process GO:0006753 162 0.059
single organism intracellular transport GO:1902582 207 0.057
chromosome organization GO:0051276 360 0.056
positive regulation of cell communication GO:0010647 250 0.050
positive regulation of signaling GO:0023056 243 0.049
single organism behavior GO:0044708 391 0.049
programmed cell death GO:0012501 257 0.048
negative regulation of nucleic acid templated transcription GO:1903507 240 0.048
rna processing GO:0006396 147 0.047
purine ribonucleotide metabolic process GO:0009150 145 0.046
tripartite regional subdivision GO:0007351 103 0.046
negative regulation of cellular biosynthetic process GO:0031327 277 0.046
purine containing compound metabolic process GO:0072521 155 0.044
cation transport GO:0006812 110 0.044
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.043
negative regulation of biosynthetic process GO:0009890 277 0.043
neurological system process GO:0050877 358 0.042
camera type eye development GO:0043010 4 0.042
response to biotic stimulus GO:0009607 294 0.042
purine ribonucleoside metabolic process GO:0046128 127 0.041
glycosyl compound catabolic process GO:1901658 112 0.040
death GO:0016265 284 0.040
negative regulation of gene expression GO:0010629 387 0.039
cellular homeostasis GO:0019725 80 0.039
ribose phosphate metabolic process GO:0019693 145 0.039
axis specification GO:0009798 167 0.038
organophosphate metabolic process GO:0019637 195 0.037
cellular response to extracellular stimulus GO:0031668 64 0.037
negative regulation of signaling GO:0023057 219 0.036
organic acid metabolic process GO:0006082 103 0.036
cellular response to external stimulus GO:0071496 66 0.036
protein modification process GO:0036211 438 0.036
endocytosis GO:0006897 310 0.035
establishment of nucleus localization GO:0040023 26 0.034
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.033
purine nucleoside triphosphate metabolic process GO:0009144 119 0.032
modification dependent macromolecule catabolic process GO:0043632 79 0.032
wnt signaling pathway GO:0016055 98 0.032
regulation of transport GO:0051049 181 0.032
purine nucleotide metabolic process GO:0006163 146 0.032
synaptic transmission GO:0007268 288 0.031
intracellular transport GO:0046907 228 0.031
ribonucleoside metabolic process GO:0009119 127 0.031
nucleobase containing compound catabolic process GO:0034655 165 0.031
retina development in camera type eye GO:0060041 4 0.030
purine containing compound catabolic process GO:0072523 112 0.030
response to mechanical stimulus GO:0009612 28 0.030
cell motility GO:0048870 251 0.030
positive regulation of signal transduction GO:0009967 223 0.030
mitotic spindle organization GO:0007052 220 0.029
nucleotide metabolic process GO:0009117 161 0.029
sensory organ morphogenesis GO:0090596 260 0.028
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.028
ovarian follicle cell development GO:0030707 248 0.028
positive regulation of biosynthetic process GO:0009891 316 0.028
karyogamy GO:0000741 4 0.028
chromatin modification GO:0016568 147 0.027
aromatic compound catabolic process GO:0019439 166 0.027
nucleobase containing small molecule metabolic process GO:0055086 174 0.027
organic substance catabolic process GO:1901575 308 0.027
chromatin organization GO:0006325 207 0.027
meiotic nuclear division GO:0007126 151 0.027
chromatin assembly or disassembly GO:0006333 52 0.027
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.026
protein modification by small protein conjugation or removal GO:0070647 106 0.026
cellular macromolecule localization GO:0070727 220 0.026
positive regulation of macromolecule metabolic process GO:0010604 405 0.026
organic substance transport GO:0071702 257 0.026
organic cyclic compound catabolic process GO:1901361 168 0.025
positive regulation of transport GO:0051050 92 0.025
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.025
meiotic cell cycle process GO:1903046 132 0.025
negative regulation of cell communication GO:0010648 223 0.025
single organism catabolic process GO:0044712 228 0.025
carbohydrate derivative metabolic process GO:1901135 217 0.025
organonitrogen compound catabolic process GO:1901565 128 0.024
ribonucleoside monophosphate catabolic process GO:0009158 39 0.024
chromatin silencing GO:0006342 76 0.024
cellular nitrogen compound catabolic process GO:0044270 165 0.024
positive regulation of response to stimulus GO:0048584 323 0.024
catabolic process GO:0009056 409 0.024
gene silencing GO:0016458 138 0.023
maintenance of location GO:0051235 73 0.023
protein targeting GO:0006605 64 0.023
pronuclear fusion GO:0007344 4 0.023
reciprocal meiotic recombination GO:0007131 19 0.022
cellular protein complex assembly GO:0043623 71 0.022
chromosome separation GO:0051304 42 0.022
negative regulation of response to stimulus GO:0048585 258 0.022
regulation of cellular amine metabolic process GO:0033238 3 0.022
circadian sleep wake cycle GO:0042745 28 0.022
negative regulation of cellular metabolic process GO:0031324 382 0.022
dna packaging GO:0006323 91 0.022
imaginal disc pattern formation GO:0007447 91 0.022
atp metabolic process GO:0046034 49 0.022
ribonucleoside triphosphate catabolic process GO:0009203 108 0.021
small molecule metabolic process GO:0044281 305 0.021
embryonic axis specification GO:0000578 107 0.021
cellular protein modification process GO:0006464 438 0.020
regulation of heart rate GO:0002027 11 0.020
multicellular organismal aging GO:0010259 140 0.020
regulation of synaptic transmission GO:0050804 69 0.020
heterocycle catabolic process GO:0046700 166 0.020
eggshell chorion assembly GO:0007306 66 0.020
protein polymerization GO:0051258 42 0.019
macromolecular complex assembly GO:0065003 256 0.019
phagocytosis GO:0006909 215 0.019
olfactory behavior GO:0042048 97 0.018
cytoplasmic transport GO:0016482 130 0.018
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.018
cellular macromolecular complex assembly GO:0034622 153 0.018
carbohydrate derivative biosynthetic process GO:1901137 85 0.018
microtubule polymerization GO:0046785 15 0.018
ribonucleotide metabolic process GO:0009259 145 0.018
actin cytoskeleton organization GO:0030036 206 0.018
positive regulation of cellular component organization GO:0051130 156 0.018
imaginal disc derived appendage development GO:0048737 399 0.017
regulation of cellular response to stress GO:0080135 89 0.017
regulation of cellular amino acid metabolic process GO:0006521 0 0.017
pole cell development GO:0007277 26 0.017
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.017
chromosome segregation GO:0007059 157 0.017
compound eye pigmentation GO:0048072 17 0.017
dna conformation change GO:0071103 105 0.017
wound healing GO:0042060 75 0.017
regulation of cellular ketone metabolic process GO:0010565 3 0.017
positive regulation of rna metabolic process GO:0051254 271 0.017
glycosyl compound metabolic process GO:1901657 127 0.016
vesicle mediated transport GO:0016192 381 0.016
kidney development GO:0001822 3 0.016
male gamete generation GO:0048232 201 0.016
spindle organization GO:0007051 253 0.016
cellular response to organic substance GO:0071310 132 0.016
cellular amine metabolic process GO:0044106 12 0.016
ribonucleoside catabolic process GO:0042454 112 0.016
macromolecule catabolic process GO:0009057 161 0.015
dna endoreduplication GO:0042023 22 0.015
localization of cell GO:0051674 257 0.015
amine metabolic process GO:0009308 12 0.015
protein complex assembly GO:0006461 200 0.015
nephron tubule development GO:0072080 3 0.015
regulation of mrna metabolic process GO:1903311 72 0.015
response to abiotic stimulus GO:0009628 341 0.015
proteolysis GO:0006508 192 0.015
nucleoside catabolic process GO:0009164 112 0.014
positive regulation of phosphorus metabolic process GO:0010562 139 0.014
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.014
response to organic substance GO:0010033 284 0.014
regulation of developmental pigmentation GO:0048070 24 0.014
regulation of cellular localization GO:0060341 136 0.014
nucleoside phosphate catabolic process GO:1901292 110 0.014
developmental maturation GO:0021700 172 0.014
purine nucleoside monophosphate metabolic process GO:0009126 50 0.014
regulation of synapse assembly GO:0051963 94 0.013
defense response to gram negative bacterium GO:0050829 94 0.013
branching morphogenesis of an epithelial tube GO:0048754 45 0.013
nucleoside monophosphate metabolic process GO:0009123 52 0.013
regulation of catabolic process GO:0009894 170 0.013
organophosphate catabolic process GO:0046434 112 0.013
compound eye development GO:0048749 307 0.013
regulation of cellular component movement GO:0051270 42 0.013
regulation of dna metabolic process GO:0051052 34 0.013
purine nucleoside monophosphate catabolic process GO:0009128 38 0.013
meiosis i GO:0007127 59 0.013
regulation of embryonic development GO:0045995 68 0.013
positive regulation of transcription dna templated GO:0045893 266 0.013
intracellular protein transport GO:0006886 104 0.013
germline stem cell asymmetric division GO:0098728 15 0.013
cellular protein catabolic process GO:0044257 83 0.013
protein localization GO:0008104 284 0.012
homeostatic process GO:0042592 199 0.012
regulation of cell cycle GO:0051726 291 0.012
defense response to bacterium GO:0042742 178 0.012
cellular protein localization GO:0034613 160 0.012
positive regulation of wnt signaling pathway GO:0030177 25 0.012
rna 3 end processing GO:0031123 45 0.012
purine nucleoside catabolic process GO:0006152 112 0.012
dna replication GO:0006260 48 0.012
dorsal ventral axis specification GO:0009950 66 0.012
head development GO:0060322 135 0.012
regulation of response to stress GO:0080134 200 0.012
regulation of transcription by chromatin organization GO:0034401 3 0.012
microtubule polymerization or depolymerization GO:0031109 39 0.012
body morphogenesis GO:0010171 2 0.011
regulation of cytoplasmic transport GO:1903649 47 0.011
nucleoside triphosphate catabolic process GO:0009143 108 0.011
regulation of cell shape GO:0008360 113 0.011
urogenital system development GO:0001655 72 0.011
cell maturation GO:0048469 144 0.011
embryo development ending in birth or egg hatching GO:0009792 152 0.011
regulation of cellular component biogenesis GO:0044087 201 0.011
female meiotic division GO:0007143 70 0.011
olfactory learning GO:0008355 56 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.011
establishment of spindle localization GO:0051293 22 0.011
purine nucleoside metabolic process GO:0042278 127 0.011
columnar cuboidal epithelial cell development GO:0002066 249 0.011
defense response GO:0006952 300 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.011
ribonucleotide catabolic process GO:0009261 109 0.011
cellular response to chemical stimulus GO:0070887 199 0.010
positive regulation of catalytic activity GO:0043085 118 0.010
development of primary sexual characteristics GO:0045137 50 0.010
imaginal disc derived wing morphogenesis GO:0007476 337 0.010
nucleoside triphosphate metabolic process GO:0009141 120 0.010
regulation of protein localization GO:0032880 76 0.010
metal ion transport GO:0030001 74 0.010

gnu disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
artery disease DOID:0050828 0 0.028
disease of anatomical entity DOID:7 0 0.028
vascular disease DOID:178 0 0.028
cardiovascular system disease DOID:1287 0 0.028
hypertension DOID:10763 0 0.023
essential hypertension DOID:10825 0 0.023