Drosophila melanogaster

122 known processes

cdc2 (Dmel_CG5363)

CG5363 gene product from transcript CG5363-RA

(Aliases: 5363,DmCdk1,cdc2Dm,CDK1/CDC2,l(2)31Eh,Cdk1,Dmel\CG5363,CG5363,CDCDm,CDK1,Dm cdc2,group 4,Dmcdc2,cdc,DmCdc2,CDC2,cdk1,Cdc2,Dcdc2)

cdc2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cell cycle GO:0051726 291 0.820
regulation of cell cycle phase transition GO:1901987 130 0.798
regulation of cell cycle process GO:0010564 181 0.769
negative regulation of mitotic cell cycle GO:0045930 109 0.749
negative regulation of cell cycle phase transition GO:1901988 103 0.693
mitotic cell cycle checkpoint GO:0007093 88 0.683
chromatin organization GO:0006325 207 0.680
Yeast Rat
mitotic cell cycle phase transition GO:0044772 138 0.670
negative regulation of cell cycle GO:0045786 116 0.660
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.627
Yeast
mitotic nuclear division GO:0007067 213 0.626
Worm
regulation of cellular catabolic process GO:0031329 157 0.622
Yeast
regulation of mitotic cell cycle phase transition GO:1901990 130 0.609
nuclear division GO:0000280 332 0.592
histone modification GO:0016570 106 0.583
Rat
cellular macromolecule catabolic process GO:0044265 136 0.547
Yeast
macromolecule catabolic process GO:0009057 161 0.523
Yeast
negative regulation of cellular metabolic process GO:0031324 382 0.521
Yeast
negative regulation of rna biosynthetic process GO:1902679 240 0.518
Yeast
mrna metabolic process GO:0016071 124 0.459
Yeast
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.454
intracellular signal transduction GO:0035556 300 0.445
Fly
organic cyclic compound catabolic process GO:1901361 168 0.418
Yeast
regulation of cellular protein metabolic process GO:0032268 243 0.403
Worm
regulation of proteasomal protein catabolic process GO:0061136 39 0.394
negative regulation of gene expression GO:0010629 387 0.393
Yeast
mitotic dna integrity checkpoint GO:0044774 75 0.389
dna metabolic process GO:0006259 227 0.370
Yeast Rat
organelle fission GO:0048285 340 0.365
spindle organization GO:0007051 253 0.358
negative regulation of cellular component organization GO:0051129 108 0.354
Yeast
regulation of protein metabolic process GO:0051246 256 0.350
Worm
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.349
Yeast Rat
catabolic process GO:0009056 409 0.346
Yeast
positive regulation of nucleic acid templated transcription GO:1903508 266 0.326
Yeast
chromosome organization GO:0051276 360 0.325
Yeast Rat
cellular macromolecule localization GO:0070727 220 0.312
Human Rat
regulation of cell differentiation GO:0045595 302 0.306
cellular protein modification process GO:0006464 438 0.260
mitotic sister chromatid separation GO:0051306 30 0.255
chromosome separation GO:0051304 42 0.253
cellular catabolic process GO:0044248 372 0.252
Yeast
rna processing GO:0006396 147 0.249
Yeast
negative regulation of transcription dna templated GO:0045892 237 0.246
Yeast
regulation of organelle organization GO:0033043 196 0.230
Yeast Worm
mitotic g2 dna damage checkpoint GO:0007095 69 0.226
regulation of mitosis GO:0007088 56 0.223
negative regulation of chromosome organization GO:2001251 19 0.222
Yeast
protein modification process GO:0036211 438 0.221
development of primary sexual characteristics GO:0045137 50 0.220
Worm
cell cycle phase transition GO:0044770 140 0.216
phosphorylation GO:0016310 294 0.212
death GO:0016265 284 0.211
Human
regulation of catabolic process GO:0009894 170 0.206
Yeast
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.199
Yeast
regulation of molecular function GO:0065009 217 0.199
Worm
mitotic sister chromatid segregation GO:0000070 87 0.196
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.193
Yeast Rat
aromatic compound catabolic process GO:0019439 166 0.193
Yeast
regulation of multicellular organismal development GO:2000026 414 0.191
Rat
regulation of growth GO:0040008 233 0.189
Yeast Rat
regulation of cell division GO:0051302 72 0.188
Yeast Worm
gene silencing GO:0016458 138 0.186
negative regulation of cell death GO:0060548 81 0.177
Human
positive regulation of gene expression GO:0010628 290 0.172
Yeast Rat
protein complex assembly GO:0006461 200 0.165
Rat
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.165
Yeast Rat
negative regulation of cellular biosynthetic process GO:0031327 277 0.163
Yeast
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.163
Yeast
meiotic nuclear division GO:0007126 151 0.161
positive regulation of biosynthetic process GO:0009891 316 0.156
Yeast Rat
negative regulation of cell cycle process GO:0010948 109 0.153
protein complex biogenesis GO:0070271 201 0.153
Rat
regulation of mitotic cell cycle GO:0007346 190 0.146
cell cycle g1 s phase transition GO:0044843 31 0.143
proteolysis GO:0006508 192 0.143
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.143
reproductive structure development GO:0048608 74 0.142
Worm
regulation of chromosome organization GO:0033044 64 0.141
Yeast
regulation of cell cycle g1 s phase transition GO:1902806 23 0.138
regulation of phosphate metabolic process GO:0019220 210 0.138
Worm
programmed cell death GO:0012501 257 0.136
Human
sex differentiation GO:0007548 81 0.134
Worm
metaphase anaphase transition of cell cycle GO:0044784 28 0.134
cell division GO:0051301 248 0.133
regulation of chromosome segregation GO:0051983 32 0.132
Yeast
cell cycle checkpoint GO:0000075 95 0.129
cellular response to dna damage stimulus GO:0006974 223 0.128
positive regulation of macromolecule metabolic process GO:0010604 405 0.128
Yeast Rat Worm
cell death GO:0008219 279 0.126
Human
regulation of nervous system development GO:0051960 248 0.121
macromolecular complex assembly GO:0065003 256 0.119
Rat
embryo development ending in birth or egg hatching GO:0009792 152 0.117
Worm
modification dependent macromolecule catabolic process GO:0043632 79 0.114
mitotic spindle organization GO:0007052 220 0.114
regulation of mitotic sister chromatid segregation GO:0033047 28 0.113
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.111
heterocycle catabolic process GO:0046700 166 0.109
Yeast
regulation of sister chromatid segregation GO:0033045 28 0.108
positive regulation of catabolic process GO:0009896 105 0.107
Yeast
sister chromatid segregation GO:0000819 92 0.106
chromatin remodeling GO:0006338 72 0.105
Yeast
cellular nitrogen compound catabolic process GO:0044270 165 0.105
Yeast
regulation of cell development GO:0060284 215 0.104
nuclear transport GO:0051169 72 0.102
Rat
regulation of protein catabolic process GO:0042176 55 0.099
cellular protein catabolic process GO:0044257 83 0.096
gene silencing by rna GO:0031047 57 0.095
regulation of phosphorylation GO:0042325 147 0.094
Worm
negative regulation of developmental process GO:0051093 201 0.088
regulation of cellular protein catabolic process GO:1903362 44 0.085
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.082
embryonic morphogenesis GO:0048598 206 0.081
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.080
regulation of intracellular signal transduction GO:1902531 236 0.078
negative regulation of cellular protein metabolic process GO:0032269 85 0.078
spindle assembly GO:0051225 80 0.075
imaginal disc derived appendage morphogenesis GO:0035114 395 0.075
mrna catabolic process GO:0006402 33 0.072
negative regulation of chromosome segregation GO:0051985 14 0.072
Yeast
protein modification by small protein conjugation or removal GO:0070647 106 0.072
regionalization GO:0003002 416 0.071
proteasomal protein catabolic process GO:0010498 59 0.071
regulation of meiotic cell cycle GO:0051445 9 0.071
Yeast Worm
intracellular transport GO:0046907 228 0.070
Rat
posttranscriptional regulation of gene expression GO:0010608 145 0.068
regulation of dna metabolic process GO:0051052 34 0.067
Yeast Rat
regulation of meiosis GO:0040020 3 0.067
Worm
regulation of phosphorus metabolic process GO:0051174 210 0.066
Worm
regulation of gene silencing GO:0060968 63 0.065
dna damage checkpoint GO:0000077 78 0.065
regulation of mitotic sister chromatid separation GO:0010965 28 0.061
covalent chromatin modification GO:0016569 106 0.059
Rat
regulation of g1 s transition of mitotic cell cycle GO:2000045 23 0.059
negative regulation of protein metabolic process GO:0051248 85 0.058
cytoplasmic transport GO:0016482 130 0.058
Rat
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.057
Yeast
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.057
negative regulation of organelle organization GO:0010639 56 0.057
Yeast
gonad development GO:0008406 50 0.057
Worm
negative regulation of apoptotic process GO:0043066 63 0.056
Human
response to organic substance GO:0010033 284 0.056
Rat
response to external biotic stimulus GO:0043207 293 0.056
g2 dna damage checkpoint GO:0031572 69 0.054
mitotic dna damage checkpoint GO:0044773 74 0.053
negative regulation of rna metabolic process GO:0051253 251 0.052
Yeast
imaginal disc derived appendage development GO:0048737 399 0.052
regulation of catalytic activity GO:0050790 185 0.050
Worm
positive regulation of cellular biosynthetic process GO:0031328 316 0.050
Yeast Rat
positive regulation of phosphorus metabolic process GO:0010562 139 0.048
Worm
regulation of dna recombination GO:0000018 4 0.048
Yeast
negative regulation of programmed cell death GO:0043069 72 0.047
Human
regulation of proteolysis GO:0030162 87 0.047
protein localization GO:0008104 284 0.046
positive regulation of cell cycle process GO:0090068 28 0.046
Yeast Worm
regulation of response to stress GO:0080134 200 0.044
Yeast
positive regulation of rna metabolic process GO:0051254 271 0.043
Yeast
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.043
Yeast
centrosome cycle GO:0007098 137 0.042
microtubule organizing center organization GO:0031023 168 0.041
Yeast
oocyte development GO:0048599 124 0.041
Worm
peptidyl amino acid modification GO:0018193 105 0.041
Human Yeast
organic substance catabolic process GO:1901575 308 0.041
Yeast
cardiovascular system development GO:0072358 82 0.040
Rat
positive regulation of phosphate metabolic process GO:0045937 139 0.040
Worm
mitotic g2 m transition checkpoint GO:0044818 70 0.039
cytokinesis GO:0000910 90 0.039
modification dependent protein catabolic process GO:0019941 78 0.039
metaphase anaphase transition of mitotic cell cycle GO:0007091 28 0.039
nucleobase containing small molecule metabolic process GO:0055086 174 0.039
organonitrogen compound metabolic process GO:1901564 318 0.039
growth GO:0040007 359 0.039
Yeast Rat
response to nitrogen compound GO:1901698 90 0.038
Rat
stem cell differentiation GO:0048863 117 0.038
ras protein signal transduction GO:0007265 88 0.037
response to organic cyclic compound GO:0014070 89 0.037
Rat
dna recombination GO:0006310 32 0.037
Yeast
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 30 0.037
protein catabolic process GO:0030163 101 0.036
rna localization GO:0006403 115 0.036
cell growth GO:0016049 108 0.035
regulation of protein modification process GO:0031399 112 0.035
Worm
single organism intracellular transport GO:1902582 207 0.035
Rat
positive regulation of mitotic cell cycle phase transition GO:1901992 20 0.034
g1 s transition of mitotic cell cycle GO:0000082 31 0.033
apoptotic process GO:0006915 159 0.033
Human
rna catabolic process GO:0006401 37 0.033
morphogenesis of an epithelium GO:0002009 276 0.033
regulation of cell death GO:0010941 173 0.032
Human
positive regulation of cellular catabolic process GO:0031331 95 0.031
Yeast
negative regulation of cell differentiation GO:0045596 143 0.031
nucleoside phosphate metabolic process GO:0006753 162 0.031
stem cell proliferation GO:0072089 88 0.031
protein ubiquitination GO:0016567 70 0.030
appendage morphogenesis GO:0035107 397 0.030
tube morphogenesis GO:0035239 191 0.030
protein maturation GO:0051604 71 0.030
negative regulation of nucleic acid templated transcription GO:1903507 240 0.030
Yeast
transcription from rna polymerase ii promoter GO:0006366 368 0.029
Yeast
adult behavior GO:0030534 137 0.028
meiotic cell cycle process GO:1903046 132 0.028
Yeast
small gtpase mediated signal transduction GO:0007264 88 0.027
neuroblast proliferation GO:0007405 74 0.027
eye development GO:0001654 323 0.027
ubiquitin dependent protein catabolic process GO:0006511 78 0.026
digestive system development GO:0055123 149 0.026
negative regulation of cell development GO:0010721 62 0.025
chromosome segregation GO:0007059 157 0.025
Yeast
rna splicing GO:0008380 83 0.025
dna templated transcription elongation GO:0006354 18 0.025
regulation of nuclear division GO:0051783 58 0.024
Worm
organophosphate metabolic process GO:0019637 195 0.024
chromatin modification GO:0016568 147 0.024
Yeast Rat
negative regulation of dna metabolic process GO:0051053 12 0.024
Yeast
dna conformation change GO:0071103 105 0.024
Rat
single organism behavior GO:0044708 391 0.024
centrosome organization GO:0051297 163 0.024
multi organism behavior GO:0051705 175 0.024
multicellular organismal aging GO:0010259 140 0.024
intracellular protein transport GO:0006886 104 0.023
Rat
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.023
Yeast
single organism catabolic process GO:0044712 228 0.023
Yeast
regulation of apoptotic process GO:0042981 130 0.023
Human
appendage development GO:0048736 401 0.023
rna splicing via transesterification reactions GO:0000375 73 0.023
cell proliferation GO:0008283 299 0.023
aging GO:0007568 143 0.022
Rat
stem cell division GO:0017145 69 0.022
negative regulation of response to stimulus GO:0048585 258 0.022
Yeast
cellular response to chemical stimulus GO:0070887 199 0.022
Rat
negative regulation of gene expression epigenetic GO:0045814 77 0.022
response to oxygen containing compound GO:1901700 200 0.021
Rat
striated muscle cell differentiation GO:0051146 90 0.021
Rat
dna dependent dna replication GO:0006261 17 0.020
Yeast
negative regulation of biosynthetic process GO:0009890 277 0.020
Yeast
segmentation GO:0035282 207 0.020
positive regulation of cell cycle GO:0045787 43 0.020
Yeast Rat Worm
genitalia development GO:0048806 26 0.019
Worm
negative regulation of catabolic process GO:0009895 36 0.019
nucleosome organization GO:0034728 59 0.019
positive regulation of transcription dna templated GO:0045893 266 0.019
Yeast
negative regulation of protein catabolic process GO:0042177 17 0.019
positive regulation of molecular function GO:0044093 136 0.019
Worm
cell maturation GO:0048469 144 0.019
Worm
protein phosphorylation GO:0006468 169 0.018
regulation of small gtpase mediated signal transduction GO:0051056 93 0.018
salivary gland development GO:0007431 162 0.018
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.018
mrna processing GO:0006397 104 0.018
Yeast
protein dna complex subunit organization GO:0071824 86 0.018
establishment or maintenance of cell polarity GO:0007163 167 0.018
negative regulation of signaling GO:0023057 219 0.018
negative regulation of cellular catabolic process GO:0031330 34 0.018
positive regulation of cellular protein metabolic process GO:0032270 118 0.018
Worm
negative regulation of proteolysis GO:0045861 31 0.017
positive regulation of protein modification process GO:0031401 58 0.017
Worm
developmental programmed cell death GO:0010623 138 0.017
post embryonic appendage morphogenesis GO:0035120 385 0.017
regulation of ras protein signal transduction GO:0046578 93 0.017
negative regulation of catalytic activity GO:0043086 42 0.017
positive regulation of nucleoside metabolic process GO:0045979 47 0.017
spindle assembly involved in mitosis GO:0090307 50 0.017
positive regulation of cellular component organization GO:0051130 156 0.017
Yeast Worm
negative regulation of protein processing GO:0010955 31 0.017
negative regulation of multicellular organismal process GO:0051241 142 0.016
positive regulation of protein metabolic process GO:0051247 128 0.016
Worm
regulation of kinase activity GO:0043549 53 0.016
Worm
positive regulation of mitotic cell cycle GO:0045931 34 0.016
Yeast Rat
regulation of neurogenesis GO:0050767 158 0.016
imaginal disc derived wing morphogenesis GO:0007476 337 0.016
gastrulation with mouth forming first GO:0001703 36 0.016
purine nucleoside triphosphate catabolic process GO:0009146 108 0.016
positive regulation of signaling GO:0023056 243 0.015
negative regulation of signal transduction GO:0009968 206 0.015
larval development GO:0002164 104 0.015
ribonucleotide metabolic process GO:0009259 145 0.015
cytoskeleton dependent cytokinesis GO:0061640 81 0.015
regulation of dna templated transcription elongation GO:0032784 17 0.015
mrna cis splicing via spliceosome GO:0045292 1 0.015
positive regulation of rna biosynthetic process GO:1902680 266 0.015
Yeast
negative regulation of proteasomal protein catabolic process GO:1901799 16 0.015
endomitotic cell cycle GO:0007113 7 0.015
embryonic pattern specification GO:0009880 174 0.015
actin cytoskeleton organization GO:0030036 206 0.015
purine containing compound metabolic process GO:0072521 155 0.014
positive regulation of catalytic activity GO:0043085 118 0.014
Worm
histolysis GO:0007559 102 0.014
oocyte differentiation GO:0009994 145 0.014
Worm
respiratory system development GO:0060541 213 0.014
regulation of cell proliferation GO:0042127 163 0.014
Rat
nucleoside catabolic process GO:0009164 112 0.014
negative regulation of cell division GO:0051782 17 0.014
regulation of programmed cell death GO:0043067 152 0.013
Human
regulation of cellular response to stress GO:0080135 89 0.013
Yeast
positive regulation of gtpase activity GO:0043547 43 0.013
nuclear export GO:0051168 24 0.013
positive regulation of cell division GO:0051781 16 0.013
Worm
nucleobase containing compound catabolic process GO:0034655 165 0.013
Yeast
cardiocyte differentiation GO:0035051 29 0.013
Rat
epithelial tube morphogenesis GO:0060562 88 0.013
negative regulation of mitotic sister chromatid separation GO:2000816 13 0.013
nucleotide metabolic process GO:0009117 161 0.013
digestive tract morphogenesis GO:0048546 127 0.013
dna integrity checkpoint GO:0031570 81 0.013
response to oxidative stress GO:0006979 86 0.013
Rat
anterior posterior axis specification embryo GO:0008595 103 0.013
negative regulation of molecular function GO:0044092 51 0.013
purine ribonucleotide metabolic process GO:0009150 145 0.013
regulation of synapse structure and activity GO:0050803 128 0.013
ribonucleotide catabolic process GO:0009261 109 0.013
positive regulation of phosphorylation GO:0042327 87 0.013
Worm
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.013
wing disc morphogenesis GO:0007472 344 0.013
tissue morphogenesis GO:0048729 297 0.013
nucleocytoplasmic transport GO:0006913 72 0.013
Rat
reproductive behavior GO:0019098 122 0.013
response to biotic stimulus GO:0009607 294 0.012
regulation of dna replication GO:0006275 13 0.012
Yeast Rat
negative regulation of homeostatic process GO:0032845 2 0.012
internal peptidyl lysine acetylation GO:0018393 38 0.012
camera type eye development GO:0043010 4 0.012
multicellular organismal reproductive behavior GO:0033057 110 0.012
poly a mrna export from nucleus GO:0016973 5 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.012
meiotic cell cycle GO:0051321 171 0.012
purine nucleoside triphosphate metabolic process GO:0009144 119 0.012
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 16 0.012
vesicle mediated transport GO:0016192 381 0.012
Yeast
circulatory system development GO:0072359 82 0.012
Rat
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.012
purine nucleotide metabolic process GO:0006163 146 0.012
multi organism reproductive behavior GO:0044705 121 0.012
nuclear transcribed mrna catabolic process GO:0000956 24 0.012
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 17 0.011
compound eye development GO:0048749 307 0.011
positive regulation of nucleotide metabolic process GO:0045981 55 0.011
imaginal disc derived leg segmentation GO:0036011 26 0.011
positive regulation of signal transduction GO:0009967 223 0.011
macromolecule methylation GO:0043414 45 0.011
response to organonitrogen compound GO:0010243 75 0.011
Rat
response to abiotic stimulus GO:0009628 341 0.011
positive regulation of response to stimulus GO:0048584 323 0.011
negative regulation of nervous system development GO:0051961 92 0.011
negative regulation of protein maturation GO:1903318 31 0.011
regulation of cell morphogenesis GO:0022604 163 0.011
protein modification by small protein conjugation GO:0032446 79 0.011
cellularization GO:0007349 90 0.011
exocrine system development GO:0035272 162 0.011
regulation of cellular component biogenesis GO:0044087 201 0.011
synapse organization GO:0050808 196 0.011
organic substance transport GO:0071702 257 0.011
Rat
protein alkylation GO:0008213 43 0.011
organelle assembly GO:0070925 198 0.011
negative regulation of neurogenesis GO:0050768 53 0.011
response to other organism GO:0051707 293 0.011
muscle cell differentiation GO:0042692 103 0.010
Rat
regulation of protein processing GO:0070613 32 0.010
ribose phosphate metabolic process GO:0019693 145 0.010
positive regulation of dna metabolic process GO:0051054 12 0.010
Yeast Rat
antimicrobial humoral response GO:0019730 99 0.010
cellular protein localization GO:0034613 160 0.010
Human Rat
regulation of multi organism process GO:0043900 131 0.010
regulation of cellular amino acid metabolic process GO:0006521 0 0.010
cellular component assembly involved in morphogenesis GO:0010927 151 0.010

cdc2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.020