Drosophila melanogaster

21 known processes

Rpn7 (Dmel_CG5378)

CG5378 gene product from transcript CG5378-RA

(Aliases: CG5378,anon-WO0172774.106,anon-WO0172774.103,141231_at,Dmel\CG5378,p42A)

Rpn7 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
proteolysis GO:0006508 192 0.819
mitotic spindle organization GO:0007052 220 0.698
mitotic spindle elongation GO:0000022 81 0.604
modification dependent protein catabolic process GO:0019941 78 0.571
Zebrafish
modification dependent macromolecule catabolic process GO:0043632 79 0.540
Zebrafish
spindle organization GO:0007051 253 0.531
cellular response to dna damage stimulus GO:0006974 223 0.440
ubiquitin dependent protein catabolic process GO:0006511 78 0.372
Zebrafish
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.329
Zebrafish
nuclear division GO:0000280 332 0.276
dna templated transcription initiation GO:0006352 25 0.241
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.221
Zebrafish
proteasomal protein catabolic process GO:0010498 59 0.219
Zebrafish
cellular macromolecule catabolic process GO:0044265 136 0.185
Zebrafish
organelle fission GO:0048285 340 0.182
protein complex biogenesis GO:0070271 201 0.174
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.172
cellular protein complex assembly GO:0043623 71 0.162
spindle elongation GO:0051231 83 0.160
mitotic nuclear division GO:0007067 213 0.143
transcription from rna polymerase ii promoter GO:0006366 368 0.130
determination of adult lifespan GO:0008340 137 0.125
Worm
proteasome assembly GO:0043248 2 0.113
transcription initiation from rna polymerase ii promoter GO:0006367 25 0.105
embryo development ending in birth or egg hatching GO:0009792 152 0.104
Worm
protein catabolic process GO:0030163 101 0.093
Zebrafish
body morphogenesis GO:0010171 2 0.093
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 20 0.092
regulation of cellular component biogenesis GO:0044087 201 0.090
cellular macromolecular complex assembly GO:0034622 153 0.086
dna templated transcriptional preinitiation complex assembly GO:0070897 20 0.084
vesicle mediated transport GO:0016192 381 0.083
cellular protein catabolic process GO:0044257 83 0.083
Zebrafish
macromolecular complex assembly GO:0065003 256 0.082
catabolic process GO:0009056 409 0.078
Zebrafish
cell proliferation GO:0008283 299 0.075
positive regulation of proteolysis GO:0045862 52 0.073
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.073
spindle assembly GO:0051225 80 0.072
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.068
regulation of proteolysis GO:0030162 87 0.066
protein dna complex subunit organization GO:0071824 86 0.058
regulation of cellular protein metabolic process GO:0032268 243 0.058
organelle assembly GO:0070925 198 0.058
multicellular organismal aging GO:0010259 140 0.057
Worm
mitotic cell cycle phase transition GO:0044772 138 0.054
spindle assembly involved in mitosis GO:0090307 50 0.053
forebrain development GO:0030900 2 0.053
macromolecule catabolic process GO:0009057 161 0.052
Zebrafish
negative regulation of gene expression GO:0010629 387 0.049
protein modification process GO:0036211 438 0.046
regulation of protein metabolic process GO:0051246 256 0.046
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 1 0.044
lateral inhibition GO:0046331 206 0.044
dna repair GO:0006281 54 0.042
death GO:0016265 284 0.042
Worm
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.042
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 24 0.041
protein complex assembly GO:0006461 200 0.041
apoptotic process GO:0006915 159 0.040
Worm
nucleoside metabolic process GO:0009116 127 0.038
aging GO:0007568 143 0.037
Worm
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.037
compound eye photoreceptor development GO:0042051 78 0.036
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 19 0.036
purine ribonucleotide metabolic process GO:0009150 145 0.036
regulation of multicellular organismal development GO:2000026 414 0.035
atp metabolic process GO:0046034 49 0.035
ras protein signal transduction GO:0007265 88 0.034
positive regulation of proteasomal protein catabolic process GO:1901800 20 0.033
regulation of proteasomal protein catabolic process GO:0061136 39 0.033
cellular protein modification process GO:0006464 438 0.033
regulation of molecular function GO:0065009 217 0.032
er associated ubiquitin dependent protein catabolic process GO:0030433 3 0.032
larval development GO:0002164 104 0.031
Worm
regulation of cell cycle GO:0051726 291 0.031
organic substance catabolic process GO:1901575 308 0.029
Zebrafish
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.029
positive regulation of catabolic process GO:0009896 105 0.029
regulation of intracellular signal transduction GO:1902531 236 0.029
positive regulation of rna metabolic process GO:0051254 271 0.028
small gtpase mediated signal transduction GO:0007264 88 0.028
cellular catabolic process GO:0044248 372 0.027
Zebrafish
programmed cell death GO:0012501 257 0.027
Worm
regionalization GO:0003002 416 0.027
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.026
protein modification by small protein conjugation or removal GO:0070647 106 0.026
regulation of catalytic activity GO:0050790 185 0.025
regulation of mitotic cell cycle GO:0007346 190 0.025
purine nucleotide metabolic process GO:0006163 146 0.025
response to organic substance GO:0010033 284 0.024
eye photoreceptor cell differentiation GO:0001754 145 0.023
ribose phosphate metabolic process GO:0019693 145 0.023
ribonucleotide metabolic process GO:0009259 145 0.023
organic cyclic compound catabolic process GO:1901361 168 0.023
cell death GO:0008219 279 0.022
Worm
regulation of phosphate metabolic process GO:0019220 210 0.022
eye photoreceptor cell development GO:0042462 81 0.022
eye development GO:0001654 323 0.022
Zebrafish
regulation of protein catabolic process GO:0042176 55 0.021
positive regulation of nucleic acid templated transcription GO:1903508 266 0.021
regulation of ras protein signal transduction GO:0046578 93 0.020
cell cycle phase transition GO:0044770 140 0.020
protein ubiquitination GO:0016567 70 0.020
endocytosis GO:0006897 310 0.020
protein neddylation GO:0045116 5 0.019
positive regulation of cellular component biogenesis GO:0044089 80 0.019
positive regulation of cellular biosynthetic process GO:0031328 316 0.019
negative regulation of signal transduction GO:0009968 206 0.019
photoreceptor cell differentiation GO:0046530 170 0.019
regulation of cell cycle process GO:0010564 181 0.019
organophosphate metabolic process GO:0019637 195 0.018
negative regulation of cellular metabolic process GO:0031324 382 0.018
purine containing compound metabolic process GO:0072521 155 0.018
phagocytosis GO:0006909 215 0.018
nucleobase containing small molecule metabolic process GO:0055086 174 0.018
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.018
positive regulation of molecular function GO:0044093 136 0.017
positive regulation of response to stimulus GO:0048584 323 0.017
mitotic dna damage checkpoint GO:0044773 74 0.016
regulation of protein modification by small protein conjugation or removal GO:1903320 25 0.016
ribonucleoside monophosphate metabolic process GO:0009161 51 0.016
cell cell signaling involved in cell fate commitment GO:0045168 210 0.016
regulation of cell division GO:0051302 72 0.016
regulation of endopeptidase activity GO:0052548 36 0.016
signal transduction by phosphorylation GO:0023014 107 0.016
ribonucleoside triphosphate metabolic process GO:0009199 119 0.016
dna templated transcription elongation GO:0006354 18 0.016
aromatic compound catabolic process GO:0019439 166 0.015
ribonucleoside metabolic process GO:0009119 127 0.015
positive regulation of peptidase activity GO:0010952 29 0.015
nucleoside phosphate metabolic process GO:0006753 162 0.015
regulation of protein modification process GO:0031399 112 0.015
regulation of organelle organization GO:0033043 196 0.015
synapse organization GO:0050808 196 0.015
intracellular signal transduction GO:0035556 300 0.015
purine nucleoside metabolic process GO:0042278 127 0.014
purine nucleoside monophosphate metabolic process GO:0009126 50 0.014
negative regulation of cell cycle process GO:0010948 109 0.014
posttranscriptional regulation of gene expression GO:0010608 145 0.014
protein dna complex assembly GO:0065004 63 0.014
regulation of striated muscle contraction GO:0006942 2 0.014
positive regulation of transcription dna templated GO:0045893 266 0.014
organic substance transport GO:0071702 257 0.014
photoreceptor cell development GO:0042461 96 0.014
positive regulation of protein metabolic process GO:0051247 128 0.013
negative regulation of biosynthetic process GO:0009890 277 0.013
positive regulation of signal transduction GO:0009967 223 0.013
positive regulation of rna biosynthetic process GO:1902680 266 0.013
positive regulation of protein catabolic process GO:0045732 34 0.013
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 4 0.013
mitotic g2 dna damage checkpoint GO:0007095 69 0.013
positive regulation of catalytic activity GO:0043085 118 0.013
negative regulation of cell cycle GO:0045786 116 0.012
positive regulation of intracellular signal transduction GO:1902533 116 0.012
positive regulation of cellular protein metabolic process GO:0032270 118 0.012
positive regulation of gene expression GO:0010628 290 0.012
nucleoside triphosphate metabolic process GO:0009141 120 0.012
positive regulation of phosphorus metabolic process GO:0010562 139 0.012
positive regulation of hydrolase activity GO:0051345 78 0.012
nucleotide metabolic process GO:0009117 161 0.012
positive regulation of protein complex assembly GO:0031334 22 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.011
dna integrity checkpoint GO:0031570 81 0.011
protein modification by small protein conjugation GO:0032446 79 0.011
compound eye photoreceptor cell differentiation GO:0001751 140 0.011
purine nucleoside triphosphate metabolic process GO:0009144 119 0.011
g2 dna damage checkpoint GO:0031572 69 0.011
negative regulation of catabolic process GO:0009895 36 0.011
morphogenesis of an epithelium GO:0002009 276 0.011
regulation of peptidase activity GO:0052547 39 0.011
protein processing GO:0016485 68 0.011
positive regulation of endopeptidase activity GO:0010950 26 0.011
appendage morphogenesis GO:0035107 397 0.011
positive regulation of cellular component organization GO:0051130 156 0.010
mapk cascade GO:0000165 107 0.010
protein localization GO:0008104 284 0.010
dendrite development GO:0016358 204 0.010
cell division GO:0051301 248 0.010
regulation of nuclear division GO:0051783 58 0.010
positive regulation of binding GO:0051099 4 0.010
positive regulation of cell communication GO:0010647 250 0.010
regulation of phosphorus metabolic process GO:0051174 210 0.010
regulation of small gtpase mediated signal transduction GO:0051056 93 0.010

Rpn7 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org