Drosophila melanogaster

0 known processes

dob (Dmel_CG5560)

doppelganger von brummer

(Aliases: CG5560,Dmel\CG5560)

dob biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sensory perception of chemical stimulus GO:0007606 116 0.161
neurological system process GO:0050877 358 0.082
small molecule metabolic process GO:0044281 305 0.082
sensory perception GO:0007600 196 0.078
carboxylic acid metabolic process GO:0019752 92 0.071
defense response GO:0006952 300 0.068
sensory perception of smell GO:0007608 80 0.067
medium chain fatty acid metabolic process GO:0051791 1 0.067
cellular catabolic process GO:0044248 372 0.066
Human
response to external biotic stimulus GO:0043207 293 0.065
oxoacid metabolic process GO:0043436 103 0.059
anion homeostasis GO:0055081 3 0.053
response to other organism GO:0051707 293 0.053
organonitrogen compound metabolic process GO:1901564 318 0.053
imaginal disc derived appendage morphogenesis GO:0035114 395 0.053
sterol homeostasis GO:0055092 4 0.051
imaginal disc derived appendage development GO:0048737 399 0.051
organic substance catabolic process GO:1901575 308 0.050
Human
response to bacterium GO:0009617 198 0.048
organic acid metabolic process GO:0006082 103 0.048
response to biotic stimulus GO:0009607 294 0.047
single organism behavior GO:0044708 391 0.046
growth GO:0040007 359 0.046
defense response to other organism GO:0098542 225 0.046
appendage morphogenesis GO:0035107 397 0.046
single organism biosynthetic process GO:0044711 206 0.044
Human
lipid metabolic process GO:0006629 121 0.044
Human
single organism catabolic process GO:0044712 228 0.041
Human
catabolic process GO:0009056 409 0.039
Human
cellular protein modification process GO:0006464 438 0.038
imaginal disc derived wing morphogenesis GO:0007476 337 0.037
vesicle mediated transport GO:0016192 381 0.036
cholesterol homeostasis GO:0042632 3 0.035
appendage development GO:0048736 401 0.035
establishment of localization in cell GO:0051649 402 0.035
wing disc morphogenesis GO:0007472 344 0.035
endocytosis GO:0006897 310 0.035
post embryonic appendage morphogenesis GO:0035120 385 0.034
triglyceride catabolic process GO:0019433 3 0.034
Human
xenobiotic catabolic process GO:0042178 1 0.033
proteolysis GO:0006508 192 0.033
protein modification process GO:0036211 438 0.033
fat soluble vitamin metabolic process GO:0006775 1 0.033
cellular amino acid metabolic process GO:0006520 61 0.033
phagocytosis GO:0006909 215 0.031
amine metabolic process GO:0009308 12 0.030
response to abiotic stimulus GO:0009628 341 0.030
regulation of lipid storage GO:0010883 22 0.030
Human
response to organophosphorus GO:0046683 2 0.029
pigment metabolic process GO:0042440 84 0.029
oxidation reduction process GO:0055114 123 0.029
regulation of cellular amine metabolic process GO:0033238 3 0.029
organic hydroxy compound metabolic process GO:1901615 83 0.029
steroid catabolic process GO:0006706 1 0.028
organic substance transport GO:0071702 257 0.028
defense response to bacterium GO:0042742 178 0.027
homeostatic process GO:0042592 199 0.027
sulfur compound metabolic process GO:0006790 59 0.027
organelle fission GO:0048285 340 0.026
developmental pigmentation GO:0048066 68 0.026
negative regulation of cellular metabolic process GO:0031324 382 0.026
response to organic substance GO:0010033 284 0.025
acylglycerol catabolic process GO:0046464 3 0.025
Human
secondary metabolite catabolic process GO:0090487 1 0.025
cell proliferation GO:0008283 299 0.025
eye pigment metabolic process GO:0042441 33 0.025
innate immune response GO:0045087 144 0.025
regulation of localization GO:0032879 275 0.025
Human
regulation of cellular ketone metabolic process GO:0010565 3 0.025
cellular lipid metabolic process GO:0044255 83 0.024
Human
intracellular signal transduction GO:0035556 300 0.024
positive regulation of cellular biosynthetic process GO:0031328 316 0.024
response to lipopolysaccharide GO:0032496 4 0.024
positive regulation of biosynthetic process GO:0009891 316 0.024
immune system process GO:0002376 347 0.023
telencephalon development GO:0021537 2 0.023
pigment biosynthetic process GO:0046148 36 0.023
death GO:0016265 284 0.023
cell death GO:0008219 279 0.023
regulation of protein metabolic process GO:0051246 256 0.023
programmed cell death GO:0012501 257 0.023
maintenance of location GO:0051235 73 0.023
Human
positive regulation of response to stimulus GO:0048584 323 0.023
vitamin biosynthetic process GO:0009110 1 0.022
protein localization GO:0008104 284 0.022
carbohydrate derivative metabolic process GO:1901135 217 0.022
cellular nitrogen compound catabolic process GO:0044270 165 0.022
positive regulation of macromolecule metabolic process GO:0010604 405 0.022
forebrain development GO:0030900 2 0.022
triglyceride biosynthetic process GO:0019432 2 0.021
Human
organic cyclic compound catabolic process GO:1901361 168 0.021
regulation of multicellular organismal development GO:2000026 414 0.021
response to oxygen containing compound GO:1901700 200 0.021
phospholipid homeostasis GO:0055091 1 0.021
regulation of catalytic activity GO:0050790 185 0.021
very long chain fatty acid metabolic process GO:0000038 4 0.021
compound eye development GO:0048749 307 0.021
nuclear division GO:0000280 332 0.021
macromolecular complex assembly GO:0065003 256 0.020
negative regulation of nervous system development GO:0051961 92 0.020
monocarboxylic acid metabolic process GO:0032787 29 0.020
regulation of response to stress GO:0080134 200 0.020
protein dna complex subunit organization GO:0071824 86 0.020
developmental growth GO:0048589 280 0.020
ethanolamine containing compound metabolic process GO:0042439 4 0.020
vitamin metabolic process GO:0006766 2 0.020
regulation of growth GO:0040008 233 0.020
phosphorylation GO:0016310 294 0.019
cellular macromolecule localization GO:0070727 220 0.019
immune response GO:0006955 246 0.019
pigmentation GO:0043473 75 0.019
cellular ketone metabolic process GO:0042180 24 0.019
defense response to gram negative bacterium GO:0050829 94 0.019
fat soluble vitamin biosynthetic process GO:0042362 1 0.019
dna conformation change GO:0071103 105 0.019
compound eye morphogenesis GO:0001745 249 0.019
regionalization GO:0003002 416 0.019
synaptic transmission GO:0007268 288 0.019
acylglycerol biosynthetic process GO:0046463 2 0.019
Human
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.018
negative regulation of gene expression GO:0010629 387 0.018
regulation of cellular protein metabolic process GO:0032268 243 0.018
positive regulation of rna biosynthetic process GO:1902680 266 0.018
heterocycle catabolic process GO:0046700 166 0.018
transcription from rna polymerase ii promoter GO:0006366 368 0.018
organonitrogen compound catabolic process GO:1901565 128 0.018
lipid catabolic process GO:0016042 21 0.018
Human
glycerolipid catabolic process GO:0046503 3 0.018
Human
pigment metabolic process involved in developmental pigmentation GO:0043324 33 0.018
regulation of phosphorus metabolic process GO:0051174 210 0.017
regulation of cell development GO:0060284 215 0.017
positive regulation of signaling GO:0023056 243 0.017
nucleotide metabolic process GO:0009117 161 0.017
regulation of cellular amino acid metabolic process GO:0006521 0 0.017
sensory organ morphogenesis GO:0090596 260 0.017
toxin metabolic process GO:0009404 2 0.017
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.017
kidney development GO:0001822 3 0.016
negative regulation of multicellular organismal process GO:0051241 142 0.016
organophosphate metabolic process GO:0019637 195 0.016
protein transport GO:0015031 155 0.016
regulation of nervous system development GO:0051960 248 0.016
polyol biosynthetic process GO:0046173 3 0.016
toxin catabolic process GO:0009407 1 0.016
lauric acid metabolic process GO:0048252 1 0.016
regulation of transport GO:0051049 181 0.016
regulation of immune system process GO:0002682 176 0.016
connective tissue development GO:0061448 3 0.016
positive regulation of signal transduction GO:0009967 223 0.016
columnar cuboidal epithelial cell development GO:0002066 249 0.016
response to mercury ion GO:0046689 3 0.016
positive regulation of nucleic acid templated transcription GO:1903508 266 0.016
acetate ester metabolic process GO:1900619 2 0.016
regulation of cell cycle GO:0051726 291 0.016
positive regulation of gene expression GO:0010628 290 0.016
negative regulation of response to stimulus GO:0048585 258 0.016
dna metabolic process GO:0006259 227 0.016
positive regulation of cell communication GO:0010647 250 0.016
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.016
eye development GO:0001654 323 0.016
central nervous system development GO:0007417 201 0.016
cellular amine metabolic process GO:0044106 12 0.016
nuclear import GO:0051170 51 0.016
negative regulation of developmental process GO:0051093 201 0.016
chemical homeostasis GO:0048878 92 0.016
positive regulation of rna metabolic process GO:0051254 271 0.016
positive regulation of lipid storage GO:0010884 4 0.016
secretion by cell GO:0032940 101 0.016
acyl coa metabolic process GO:0006637 3 0.016
gland development GO:0048732 191 0.016
adult behavior GO:0030534 137 0.016
regulation of neurogenesis GO:0050767 158 0.016
insecticide catabolic process GO:0046701 1 0.016
salivary gland development GO:0007431 162 0.015
molting cycle chitin based cuticle GO:0007591 56 0.015
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.015
lipid storage GO:0019915 38 0.015
Human
carbohydrate derivative biosynthetic process GO:1901137 85 0.015
response to organic cyclic compound GO:0014070 89 0.015
regulation of developmental growth GO:0048638 174 0.015
chromosome segregation GO:0007059 157 0.015
cellular response to chemical stimulus GO:0070887 199 0.015
protein complex assembly GO:0006461 200 0.015
purine ribonucleotide metabolic process GO:0009150 145 0.015
nucleobase containing small molecule metabolic process GO:0055086 174 0.015
regulation of immune response GO:0050776 118 0.015
protein phosphorylation GO:0006468 169 0.015
response to endogenous stimulus GO:0009719 119 0.015
regulation of intracellular signal transduction GO:1902531 236 0.015
axonogenesis GO:0007409 290 0.015
synapse organization GO:0050808 196 0.015
positive regulation of sequestering of triglyceride GO:0010890 1 0.015
nucleoside phosphate metabolic process GO:0006753 162 0.015
positive regulation of catalytic activity GO:0043085 118 0.015
eye pigmentation GO:0048069 43 0.015
cholesterol transport GO:0030301 2 0.015
chemotaxis GO:0006935 249 0.015
pigment metabolic process involved in pigmentation GO:0043474 33 0.014
camera type eye development GO:0043010 4 0.014
negative regulation of signaling GO:0023057 219 0.014
wound healing GO:0042060 75 0.014
multi organism behavior GO:0051705 175 0.014
cellular protein localization GO:0034613 160 0.014
protein complex biogenesis GO:0070271 201 0.014
regulation of cell cycle process GO:0010564 181 0.014
body morphogenesis GO:0010171 2 0.014
macromolecule catabolic process GO:0009057 161 0.014
regulation of phosphorylation GO:0042325 147 0.014
axon guidance GO:0007411 233 0.014
peptidyl amino acid modification GO:0018193 105 0.014
dendrite development GO:0016358 204 0.014
cell cell signaling involved in cell fate commitment GO:0045168 210 0.014
negative regulation of signal transduction GO:0009968 206 0.014
secretion GO:0046903 109 0.014
positive regulation of multicellular organismal process GO:0051240 143 0.014
regulation of apoptotic process GO:0042981 130 0.014
establishment of protein localization GO:0045184 163 0.014
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.014
single organism cellular localization GO:1902580 180 0.014
response to monosaccharide GO:0034284 4 0.014
locomotory behavior GO:0007626 176 0.013
response to nitrogen compound GO:1901698 90 0.013
neuron projection guidance GO:0097485 241 0.013
cytoplasmic transport GO:0016482 130 0.013
regulation of cellular localization GO:0060341 136 0.013
phosphatidylethanolamine metabolic process GO:0046337 1 0.013
antimicrobial humoral response GO:0019730 99 0.013
insecticide metabolic process GO:0017143 2 0.013
neuron recognition GO:0008038 101 0.013
androgen metabolic process GO:0008209 1 0.013
cell cycle phase transition GO:0044770 140 0.013
regulation of cell death GO:0010941 173 0.013
regulation of cell proliferation GO:0042127 163 0.013
positive regulation of phosphorus metabolic process GO:0010562 139 0.013
regulation of cell differentiation GO:0045595 302 0.013
small gtpase mediated signal transduction GO:0007264 88 0.013
aromatic compound catabolic process GO:0019439 166 0.013
cellular amide metabolic process GO:0043603 80 0.013
response to radiation GO:0009314 155 0.013
axon development GO:0061564 297 0.013
response to glucose GO:0009749 2 0.013
cell recognition GO:0008037 102 0.013
protein localization to organelle GO:0033365 82 0.013
apoptotic process GO:0006915 159 0.013
oocyte construction GO:0007308 112 0.013
response to copper ion GO:0046688 4 0.013
regulation of cell cycle phase transition GO:1901987 130 0.013
positive regulation of molecular function GO:0044093 136 0.013
eye morphogenesis GO:0048592 260 0.013
response to hexose GO:0009746 3 0.013
positive regulation of defense response GO:0031349 59 0.013
purine nucleotide metabolic process GO:0006163 146 0.012
regulation of response to external stimulus GO:0032101 115 0.012
tissue death GO:0016271 102 0.012
lipid homeostasis GO:0055088 33 0.012
single organism intracellular transport GO:1902582 207 0.012
biological adhesion GO:0022610 138 0.012
estrogen metabolic process GO:0008210 1 0.012
gland morphogenesis GO:0022612 145 0.012
phosphatidic acid metabolic process GO:0046473 1 0.012
protein targeting to nucleus GO:0044744 51 0.012
ras protein signal transduction GO:0007265 88 0.012
negative regulation of cell differentiation GO:0045596 143 0.012
regulation of phosphate metabolic process GO:0019220 210 0.012
cuticle development GO:0042335 86 0.012
cellular response to dna damage stimulus GO:0006974 223 0.012
regulation of molecular function GO:0065009 217 0.012
negative regulation of cellular protein metabolic process GO:0032269 85 0.012
cellular response to hexose stimulus GO:0071331 1 0.012
regulation of multi organism process GO:0043900 131 0.012
chromosome organization GO:0051276 360 0.012
purine containing compound metabolic process GO:0072521 155 0.012
response to extracellular stimulus GO:0009991 116 0.012
nucleobase containing compound catabolic process GO:0034655 165 0.012
enzyme linked receptor protein signaling pathway GO:0007167 179 0.012
intracellular transport GO:0046907 228 0.012
mitotic nuclear division GO:0007067 213 0.012
signal transduction by phosphorylation GO:0023014 107 0.012
response to nutrient levels GO:0031667 114 0.012
alditol phosphate metabolic process GO:0052646 2 0.012
cellular macromolecule catabolic process GO:0044265 136 0.012
blastoderm segmentation GO:0007350 159 0.012
regulation of defense response GO:0031347 102 0.012
positive regulation of phosphate metabolic process GO:0045937 139 0.012
negative regulation of biosynthetic process GO:0009890 277 0.012
histolysis GO:0007559 102 0.012
single organism nuclear import GO:1902593 51 0.012
taxis GO:0042330 304 0.012
ion transport GO:0006811 145 0.012
tissue migration GO:0090130 155 0.012
acetylcholine metabolic process GO:0008291 2 0.012
salivary gland morphogenesis GO:0007435 145 0.012
organophosphate catabolic process GO:0046434 112 0.012
positive regulation of transport GO:0051050 92 0.012
eye antennal disc development GO:0035214 60 0.011
open tracheal system development GO:0007424 204 0.011
positive regulation of protein metabolic process GO:0051247 128 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
salivary gland cell autophagic cell death GO:0035071 83 0.011
cellular response to biotic stimulus GO:0071216 4 0.011
benzene containing compound metabolic process GO:0042537 3 0.011
positive regulation of transcription dna templated GO:0045893 266 0.011
dendrite morphogenesis GO:0048813 199 0.011
epithelial cell differentiation GO:0030855 322 0.011
regulation of lipid transport GO:0032368 3 0.011
mapk cascade GO:0000165 107 0.011
regulation of programmed cell death GO:0043067 152 0.011
response to temperature stimulus GO:0009266 106 0.011
negative regulation of protein metabolic process GO:0051248 85 0.011
developmental programmed cell death GO:0010623 138 0.011
negative regulation of cell communication GO:0010648 223 0.011
intracellular protein transport GO:0006886 104 0.011
regulation of anatomical structure size GO:0090066 163 0.011
positive regulation of cell migration GO:0030335 2 0.011
determination of adult lifespan GO:0008340 137 0.011
positive regulation of immune system process GO:0002684 68 0.011
jak stat cascade GO:0007259 49 0.011
regulation of notch signaling pathway GO:0008593 100 0.011
regulation of mitotic cell cycle GO:0007346 190 0.011
neurotransmitter metabolic process GO:0042133 2 0.011
negative regulation of cell death GO:0060548 81 0.011
ribonucleotide metabolic process GO:0009259 145 0.011
cellular response to organic substance GO:0071310 132 0.011
developmental maturation GO:0021700 172 0.011
cellular homeostasis GO:0019725 80 0.011
negative regulation of cellular biosynthetic process GO:0031327 277 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.011
mitotic cell cycle phase transition GO:0044772 138 0.011
cellular macromolecular complex assembly GO:0034622 153 0.011
spermatogenesis GO:0007283 200 0.011
cellular response to mechanical stimulus GO:0071260 2 0.011
regulation of gene expression epigenetic GO:0040029 128 0.011
proteasomal protein catabolic process GO:0010498 59 0.011
regulation of organelle organization GO:0033043 196 0.011
learning or memory GO:0007611 141 0.011
humoral immune response GO:0006959 117 0.011
chemosensory behavior GO:0007635 106 0.011
regulation of synapse structure and activity GO:0050803 128 0.011
hematopoietic progenitor cell differentiation GO:0002244 1 0.011
positive regulation of phosphorylation GO:0042327 87 0.011
lateral inhibition GO:0046331 206 0.011
meiotic cell cycle process GO:1903046 132 0.011
dna packaging GO:0006323 91 0.011
cellular response to lipopolysaccharide GO:0071222 3 0.010
cellular response to molecule of bacterial origin GO:0071219 3 0.010
axis specification GO:0009798 167 0.010
molting cycle process GO:0022404 29 0.010
exocrine system development GO:0035272 162 0.010
regulation of cellular component biogenesis GO:0044087 201 0.010
dorsal ventral pattern formation GO:0009953 133 0.010
mitotic g2 m transition checkpoint GO:0044818 70 0.010
positive regulation of cellular protein metabolic process GO:0032270 118 0.010
nucleocytoplasmic transport GO:0006913 72 0.010
ribonucleoside metabolic process GO:0009119 127 0.010
adult locomotory behavior GO:0008344 76 0.010
glycosyl compound metabolic process GO:1901657 127 0.010
segmentation GO:0035282 207 0.010
cell cycle checkpoint GO:0000075 95 0.010
negative regulation of rna metabolic process GO:0051253 251 0.010
positive regulation of immune response GO:0050778 63 0.010
respiratory system development GO:0060541 213 0.010
positive regulation of cell motility GO:2000147 3 0.010
organic hydroxy compound catabolic process GO:1901616 4 0.010
spindle organization GO:0007051 253 0.010
regulation of epithelial cell proliferation GO:0050678 4 0.010
positive regulation of cellular catabolic process GO:0031331 95 0.010
Human
embryonic pattern specification GO:0009880 174 0.010
eggshell formation GO:0030703 105 0.010
ameboidal type cell migration GO:0001667 151 0.010

dob disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.095
disease of metabolism DOID:0014667 0 0.046
inherited metabolic disorder DOID:655 0 0.046
artery disease DOID:0050828 0 0.026
vascular disease DOID:178 0 0.026
cardiovascular system disease DOID:1287 0 0.026
nervous system disease DOID:863 0 0.023
hypertension DOID:10763 0 0.022
essential hypertension DOID:10825 0 0.022
acquired metabolic disease DOID:0060158 0 0.015
carbohydrate metabolism disease DOID:0050013 0 0.014
glucose metabolism disease DOID:4194 0 0.014
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
central nervous system disease DOID:331 0 0.012
neurodegenerative disease DOID:1289 0 0.012
diabetes mellitus DOID:9351 0 0.012
urinary system disease DOID:18 0 0.012
hair disease DOID:421 0 0.011
integumentary system disease DOID:16 0 0.011
hypotrichosis DOID:4535 0 0.011
familial lipoprotein lipase deficiency DOID:14118 0 0.011
familial hyperlipidemia DOID:1168 0 0.011
lipid metabolism disorder DOID:3146 0 0.011
familial combined hyperlipidemia DOID:13809 0 0.011
type 2 diabetes mellitus DOID:9352 0 0.010
kidney disease DOID:557 0 0.010