|
|
regulation of pathway restricted smad protein phosphorylation
|
GO:0060393 |
1 |
1.000
|
Human Mouse |
|
|
imaginal disc derived appendage development
|
GO:0048737 |
399 |
0.999
|
|
|
|
appendage development
|
GO:0048736 |
401 |
0.998
|
|
|
|
post embryonic appendage morphogenesis
|
GO:0035120 |
385 |
0.992
|
|
|
|
imaginal disc derived wing morphogenesis
|
GO:0007476 |
337 |
0.990
|
|
|
|
regulation of transcription from rna polymerase ii promoter
|
GO:0006357 |
378 |
0.986
|
Human Zebrafish Mouse |
|
|
bmp signaling pathway
|
GO:0030509 |
27 |
0.979
|
Human Zebrafish Mouse |
|
|
imaginal disc derived appendage morphogenesis
|
GO:0035114 |
395 |
0.976
|
|
|
|
wing disc morphogenesis
|
GO:0007472 |
344 |
0.967
|
|
|
|
columnar cuboidal epithelial cell differentiation
|
GO:0002065 |
256 |
0.966
|
|
|
|
regionalization
|
GO:0003002 |
416 |
0.962
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
397 |
0.959
|
|
|
|
determination of ventral identity
|
GO:0048264 |
1 |
0.957
|
Zebrafish |
|
|
positive regulation of pathway restricted smad protein phosphorylation
|
GO:0010862 |
1 |
0.956
|
Human Mouse |
|
|
notch signaling pathway
|
GO:0007219 |
120 |
0.939
|
Mouse |
|
|
ovarian follicle cell development
|
GO:0030707 |
248 |
0.937
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
159 |
0.933
|
|
|
|
compound eye morphogenesis
|
GO:0001745 |
249 |
0.928
|
|
|
|
epithelial cell development
|
GO:0002064 |
274 |
0.926
|
|
|
|
taxis
|
GO:0042330 |
304 |
0.925
|
Mouse |
|
|
eye morphogenesis
|
GO:0048592 |
260 |
0.921
|
Mouse |
|
|
positive regulation of cellular component organization
|
GO:0051130 |
156 |
0.904
|
|
|
|
cell migration
|
GO:0016477 |
238 |
0.894
|
|
|
|
embryonic pattern specification
|
GO:0009880 |
174 |
0.892
|
Mouse |
|
|
single organism behavior
|
GO:0044708 |
391 |
0.886
|
|
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
23 |
0.882
|
|
|
|
synaptic transmission
|
GO:0007268 |
288 |
0.879
|
|
|
|
tube development
|
GO:0035295 |
244 |
0.875
|
Zebrafish Mouse |
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
65 |
0.865
|
Human Zebrafish Mouse |
|
|
morphogenesis of an epithelium
|
GO:0002009 |
276 |
0.856
|
Zebrafish Mouse |
|
|
anterior posterior pattern specification
|
GO:0009952 |
136 |
0.855
|
|
|
|
cellular macromolecule localization
|
GO:0070727 |
220 |
0.854
|
Human |
|
|
germ line stem cell maintenance
|
GO:0030718 |
50 |
0.853
|
|
|
|
segmentation
|
GO:0035282 |
207 |
0.843
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
38 |
0.828
|
Human Mouse |
|
|
positive regulation of bmp signaling pathway
|
GO:0030513 |
5 |
0.811
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
297 |
0.774
|
Zebrafish Mouse |
|
|
imaginal disc derived wing vein specification
|
GO:0007474 |
48 |
0.774
|
|
|
|
response to light stimulus
|
GO:0009416 |
124 |
0.766
|
|
|
|
homeostatic process
|
GO:0042592 |
199 |
0.765
|
Human Mouse |
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
85 |
0.765
|
|
|
|
brain development
|
GO:0007420 |
120 |
0.758
|
|
|
|
eye development
|
GO:0001654 |
323 |
0.743
|
Mouse |
|
|
mesoderm morphogenesis
|
GO:0048332 |
22 |
0.742
|
Mouse |
|
|
mesoderm formation
|
GO:0001707 |
21 |
0.737
|
Mouse |
|
|
negative regulation of cellular macromolecule biosynthetic process
|
GO:2000113 |
267 |
0.724
|
Human |
|
|
adult locomotory behavior
|
GO:0008344 |
76 |
0.719
|
|
|
|
single organism cellular localization
|
GO:1902580 |
180 |
0.713
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
149 |
0.711
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
35 |
0.710
|
|
|
|
dna metabolic process
|
GO:0006259 |
227 |
0.709
|
Human |
|
|
male gamete generation
|
GO:0048232 |
201 |
0.696
|
Mouse |
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
4 |
0.688
|
Human Mouse |
|
|
spermatogenesis
|
GO:0007283 |
200 |
0.684
|
Mouse |
|
|
digestive tract development
|
GO:0048565 |
149 |
0.677
|
Zebrafish Mouse |
|
|
response to radiation
|
GO:0009314 |
155 |
0.672
|
|
|
|
heart morphogenesis
|
GO:0003007 |
32 |
0.656
|
Zebrafish |
|
|
autophagy
|
GO:0006914 |
108 |
0.640
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
140 |
0.634
|
|
|
|
nephron development
|
GO:0072006 |
3 |
0.632
|
Human Mouse |
|
|
digestive system development
|
GO:0055123 |
149 |
0.632
|
Zebrafish Mouse |
|
|
synaptic vesicle localization
|
GO:0097479 |
53 |
0.629
|
|
|
|
muscle organ development
|
GO:0007517 |
127 |
0.616
|
|
|
|
regulation of muscle organ development
|
GO:0048634 |
13 |
0.615
|
|
|
|
chemotaxis
|
GO:0006935 |
249 |
0.610
|
Mouse |
|
|
synapse organization
|
GO:0050808 |
196 |
0.608
|
|
|
|
renal tubule development
|
GO:0061326 |
64 |
0.601
|
|
|
|
axon development
|
GO:0061564 |
297 |
0.592
|
Mouse |
|
|
tube morphogenesis
|
GO:0035239 |
191 |
0.581
|
Zebrafish Mouse |
|
|
establishment or maintenance of cell polarity
|
GO:0007163 |
167 |
0.580
|
|
|
|
cell fate specification
|
GO:0001708 |
71 |
0.574
|
Zebrafish |
|
|
kidney morphogenesis
|
GO:0060993 |
3 |
0.567
|
Mouse |
|
|
positive regulation of signal transduction
|
GO:0009967 |
223 |
0.561
|
Human Mouse |
|
|
locomotory behavior
|
GO:0007626 |
176 |
0.561
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
103 |
0.555
|
Human Mouse |
|
|
intracellular signal transduction
|
GO:0035556 |
300 |
0.549
|
Human Mouse |
|
|
anterior posterior pattern specification imaginal disc
|
GO:0007448 |
16 |
0.548
|
|
|
|
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090100 |
9 |
0.541
|
Human Mouse |
|
|
organelle fission
|
GO:0048285 |
340 |
0.535
|
Human |
|
|
positive regulation of signaling
|
GO:0023056 |
243 |
0.522
|
Human Mouse |
|
|
pathway restricted smad protein phosphorylation
|
GO:0060389 |
1 |
0.518
|
Human Mouse |
|
|
hindgut morphogenesis
|
GO:0007442 |
58 |
0.509
|
|
|
|
negative regulation of cellular biosynthetic process
|
GO:0031327 |
277 |
0.509
|
Human |
|
|
gastrulation
|
GO:0007369 |
70 |
0.506
|
Zebrafish Mouse |
|
|
epithelial cell differentiation
|
GO:0030855 |
322 |
0.503
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
291 |
0.500
|
Human |
|
|
establishment of localization in cell
|
GO:0051649 |
402 |
0.494
|
|
|
|
synaptic growth at neuromuscular junction
|
GO:0051124 |
119 |
0.488
|
|
|
|
axis specification
|
GO:0009798 |
167 |
0.482
|
|
|
|
regulation of notch signaling pathway
|
GO:0008593 |
100 |
0.479
|
Mouse |
|
|
determination of dorsal ventral asymmetry
|
GO:0048262 |
3 |
0.474
|
Zebrafish |
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
57 |
0.473
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
260 |
0.463
|
Mouse |
|
|
regulation of cell development
|
GO:0060284 |
215 |
0.461
|
Human Mouse |
|
|
cell motility
|
GO:0048870 |
251 |
0.459
|
|
|
|
heart process
|
GO:0003015 |
37 |
0.452
|
|
|
|
malpighian tubule morphogenesis
|
GO:0007443 |
44 |
0.449
|
|
|
|
epithelial cell migration
|
GO:0010631 |
148 |
0.443
|
|
|
|
adult behavior
|
GO:0030534 |
137 |
0.443
|
|
|
|
imaginal disc derived wing vein morphogenesis
|
GO:0008586 |
44 |
0.436
|
|
|
|
negative regulation of response to stimulus
|
GO:0048585 |
258 |
0.434
|
Human Mouse |
|
|
transcription from rna polymerase ii promoter
|
GO:0006366 |
368 |
0.433
|
Human Zebrafish Mouse |
|
|
negative regulation of cell cycle
|
GO:0045786 |
116 |
0.433
|
Human |
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
190 |
0.431
|
Human |
|
|
compound eye development
|
GO:0048749 |
307 |
0.431
|
|
|
|
single organism membrane organization
|
GO:0044802 |
93 |
0.424
|
|
|
|
connective tissue development
|
GO:0061448 |
3 |
0.410
|
Human |
|
|
stem cell differentiation
|
GO:0048863 |
117 |
0.405
|
Human Mouse |
|
|
immune response
|
GO:0006955 |
246 |
0.385
|
Human |
|
|
kidney epithelium development
|
GO:0072073 |
3 |
0.384
|
Mouse |
|
|
body morphogenesis
|
GO:0010171 |
2 |
0.382
|
|
|
|
positive regulation of cell communication
|
GO:0010647 |
250 |
0.379
|
Human Mouse |
|
|
negative regulation of hormone biosynthetic process
|
GO:0032353 |
1 |
0.368
|
Human |
|
|
synaptic vesicle transport
|
GO:0048489 |
50 |
0.367
|
|
|
|
dorsal ventral pattern formation
|
GO:0009953 |
133 |
0.365
|
Zebrafish Fly |
|
|
signal release
|
GO:0023061 |
49 |
0.362
|
|
|
|
axon guidance
|
GO:0007411 |
233 |
0.352
|
Mouse |
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
138 |
0.348
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
78 |
0.342
|
Mouse |
|
|
negative regulation of developmental process
|
GO:0051093 |
201 |
0.339
|
Human Zebrafish Mouse |
|
|
single organism cell adhesion
|
GO:0098602 |
47 |
0.334
|
Human |
|
|
central nervous system development
|
GO:0007417 |
201 |
0.334
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
248 |
0.330
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
116 |
0.325
|
Human |
|
|
stem cell maintenance
|
GO:0019827 |
67 |
0.319
|
Mouse |
|
|
regulation of neurogenesis
|
GO:0050767 |
158 |
0.314
|
Human Mouse |
|
|
ameboidal type cell migration
|
GO:0001667 |
151 |
0.314
|
|
|
|
regulation of cell migration
|
GO:0030334 |
22 |
0.311
|
|
|
|
amine metabolic process
|
GO:0009308 |
12 |
0.309
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
2 |
0.309
|
Human |
|
|
positive regulation of response to stimulus
|
GO:0048584 |
323 |
0.306
|
Human Mouse |
|
|
negative regulation of gene expression
|
GO:0010629 |
387 |
0.306
|
Human Fly |
|
|
membrane organization
|
GO:0061024 |
112 |
0.304
|
|
|
|
endoderm formation
|
GO:0001706 |
3 |
0.300
|
Zebrafish |
|
|
catabolic process
|
GO:0009056 |
409 |
0.296
|
|
|
|
forebrain development
|
GO:0030900 |
2 |
0.294
|
|
|
|
negative regulation of cellular metabolic process
|
GO:0031324 |
382 |
0.288
|
Human |
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.288
|
|
|
|
enteroendocrine cell differentiation
|
GO:0035883 |
1 |
0.282
|
Human |
|
|
cell division
|
GO:0051301 |
248 |
0.282
|
Human |
|
|
localization of cell
|
GO:0051674 |
257 |
0.281
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
109 |
0.280
|
Human |
|
|
regulation of heart morphogenesis
|
GO:2000826 |
3 |
0.275
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
18 |
0.272
|
|
|
|
regulation of synaptic transmission
|
GO:0050804 |
69 |
0.269
|
|
|
|
malpighian tubule development
|
GO:0072002 |
64 |
0.265
|
|
|
|
exocrine system development
|
GO:0035272 |
162 |
0.263
|
Mouse |
|
|
kidney development
|
GO:0001822 |
3 |
0.257
|
Human Mouse |
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
93 |
0.257
|
|
|
|
negative regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030512 |
4 |
0.254
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
130 |
0.253
|
|
|
|
positive regulation of multicellular organismal process
|
GO:0051240 |
143 |
0.252
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
145 |
0.251
|
|
|
|
negative regulation of cell communication
|
GO:0010648 |
223 |
0.248
|
Human Mouse |
|
|
wing disc anterior posterior pattern formation
|
GO:0048100 |
5 |
0.248
|
|
|
|
negative regulation of autophagy
|
GO:0010507 |
16 |
0.246
|
|
|
|
cell surface receptor signaling pathway involved in heart development
|
GO:0061311 |
3 |
0.246
|
Zebrafish |
|
|
negative regulation of nitrogen compound metabolic process
|
GO:0051172 |
265 |
0.243
|
Human |
|
|
imaginal disc growth
|
GO:0007446 |
37 |
0.242
|
|
|
|
regulation of heart contraction
|
GO:0008016 |
21 |
0.242
|
|
|
|
embryonic axis specification
|
GO:0000578 |
107 |
0.240
|
|
|
|
urogenital system development
|
GO:0001655 |
72 |
0.239
|
Human Mouse |
|
|
myotube cell development
|
GO:0014904 |
3 |
0.238
|
|
|
|
tissue migration
|
GO:0090130 |
155 |
0.237
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
109 |
0.234
|
|
|
|
open tracheal system development
|
GO:0007424 |
204 |
0.233
|
|
|
|
establishment of vesicle localization
|
GO:0051650 |
51 |
0.230
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
142 |
0.230
|
Human Zebrafish Mouse |
|
|
meiotic cell cycle
|
GO:0051321 |
171 |
0.230
|
|
|
|
neuromuscular synaptic transmission
|
GO:0007274 |
67 |
0.226
|
|
|
|
morphogenesis of an epithelial bud
|
GO:0060572 |
3 |
0.226
|
Mouse |
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
18 |
0.224
|
|
|
|
cellular protein localization
|
GO:0034613 |
160 |
0.221
|
Human |
|
|
organelle localization
|
GO:0051640 |
148 |
0.221
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
161 |
0.216
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
179 |
0.212
|
Human Zebrafish Mouse |
|
|
endodermal cell differentiation
|
GO:0035987 |
3 |
0.211
|
Zebrafish |
|
|
muscle structure development
|
GO:0061061 |
224 |
0.206
|
|
|
|
positive regulation of synapse assembly
|
GO:0051965 |
29 |
0.205
|
|
|
|
oocyte development
|
GO:0048599 |
124 |
0.200
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
15 |
0.198
|
|
|
|
muscle tissue development
|
GO:0060537 |
30 |
0.190
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
302 |
0.189
|
Human Zebrafish Mouse |
|
|
renal tubule morphogenesis
|
GO:0061333 |
44 |
0.188
|
|
|
|
cellular catabolic process
|
GO:0044248 |
372 |
0.185
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
109 |
0.183
|
Human |
|
|
eggshell formation
|
GO:0030703 |
105 |
0.183
|
|
|
|
establishment of planar polarity
|
GO:0001736 |
87 |
0.182
|
|
|
|
secretion
|
GO:0046903 |
109 |
0.178
|
|
|
|
protein localization
|
GO:0008104 |
284 |
0.176
|
Human |
|
|
cognition
|
GO:0050890 |
141 |
0.176
|
|
|
|
negative regulation of signaling
|
GO:0023057 |
219 |
0.176
|
Human Mouse |
|
|
columnar cuboidal epithelial cell development
|
GO:0002066 |
249 |
0.174
|
|
|
|
imaginal disc pattern formation
|
GO:0007447 |
91 |
0.174
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
103 |
0.172
|
|
|
|
cell junction organization
|
GO:0034330 |
57 |
0.172
|
|
|
|
circulatory system development
|
GO:0072359 |
82 |
0.171
|
Human Zebrafish |
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
6 |
0.165
|
|
|
|
response to organic substance
|
GO:0010033 |
284 |
0.160
|
Human |
|
|
cell elongation involved in imaginal disc derived wing morphogenesis
|
GO:0090254 |
5 |
0.159
|
|
|
|
response to starvation
|
GO:0042594 |
97 |
0.157
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
206 |
0.156
|
Zebrafish Mouse |
|
|
negative regulation of cell development
|
GO:0010721 |
62 |
0.156
|
Human Mouse |
|
|
negative regulation of signal transduction
|
GO:0009968 |
206 |
0.155
|
Human Mouse |
|
|
heart development
|
GO:0007507 |
82 |
0.154
|
Zebrafish |
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
41 |
0.153
|
|
|
|
skeletal muscle fiber development
|
GO:0048741 |
3 |
0.150
|
|
|
|
circulatory system process
|
GO:0003013 |
37 |
0.148
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
24 |
0.146
|
Human |
|
|
positive regulation of developmental process
|
GO:0051094 |
143 |
0.146
|
|
|
|
carbohydrate derivative metabolic process
|
GO:1901135 |
217 |
0.142
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
341 |
0.141
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
80 |
0.139
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
88 |
0.139
|
Zebrafish Mouse |
|
|
nephron tubule morphogenesis
|
GO:0072078 |
3 |
0.139
|
|
|
|
axonogenesis
|
GO:0007409 |
290 |
0.137
|
Mouse |
|
|
renal system development
|
GO:0072001 |
72 |
0.136
|
Human Mouse |
|
|
regulation of map kinase activity
|
GO:0043405 |
17 |
0.136
|
Human |
|
|
ion transport
|
GO:0006811 |
145 |
0.136
|
|
|
|
germ line stem cell division
|
GO:0042078 |
25 |
0.136
|
|
|
|
programmed cell death
|
GO:0012501 |
257 |
0.136
|
Mouse |
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
130 |
0.135
|
|
|
|
neuron projection guidance
|
GO:0097485 |
241 |
0.134
|
Mouse |
|
|
developmental maturation
|
GO:0021700 |
172 |
0.134
|
|
|
|
regulation of localization
|
GO:0032879 |
275 |
0.134
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
2 |
0.134
|
|
|
|
apoptotic process involved in morphogenesis
|
GO:0060561 |
3 |
0.132
|
Mouse |
|
|
negative regulation of biosynthetic process
|
GO:0009890 |
277 |
0.131
|
Human |
|
|
cellular response to organic substance
|
GO:0071310 |
132 |
0.130
|
Human |
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
89 |
0.127
|
|
|
|
regulation of cell motility
|
GO:2000145 |
23 |
0.126
|
|
|
|
protein catabolic process
|
GO:0030163 |
101 |
0.125
|
|
|
|
heart contraction
|
GO:0060047 |
26 |
0.124
|
|
|
|
regulation of developmental growth
|
GO:0048638 |
174 |
0.124
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
50 |
0.123
|
|
|
|
positive regulation of transcription dna templated
|
GO:0045893 |
266 |
0.121
|
Human Mouse |
|
|
establishment of synaptic vesicle localization
|
GO:0097480 |
50 |
0.120
|
|
|
|
blood circulation
|
GO:0008015 |
26 |
0.119
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
3 |
0.118
|
|
|
|
head development
|
GO:0060322 |
135 |
0.118
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
97 |
0.116
|
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
18 |
0.116
|
|
|
|
salivary gland development
|
GO:0007431 |
162 |
0.114
|
Mouse |
|
|
response to nutrient levels
|
GO:0031667 |
114 |
0.112
|
Human Mouse |
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
103 |
0.111
|
|
|
|
positive regulation of synaptic growth at neuromuscular junction
|
GO:0045887 |
26 |
0.107
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
27 |
0.107
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
94 |
0.107
|
Mouse |
|
|
regulation of g1 s transition of mitotic cell cycle
|
GO:2000045 |
23 |
0.106
|
|
|
|
larval lymph gland hemopoiesis
|
GO:0035167 |
17 |
0.105
|
|
|
|
protein complex assembly
|
GO:0006461 |
200 |
0.103
|
Zebrafish |
|
|
positive regulation of macromolecule biosynthetic process
|
GO:0010557 |
283 |
0.102
|
Human Mouse |
|
|
regulation of apoptotic process
|
GO:0042981 |
130 |
0.101
|
Mouse |
|
|
torso signaling pathway
|
GO:0008293 |
21 |
0.100
|
|
|
|
eye photoreceptor cell differentiation
|
GO:0001754 |
145 |
0.099
|
|
|
|
negative regulation of nucleobase containing compound metabolic process
|
GO:0045934 |
261 |
0.099
|
Human |
|
|
formation of primary germ layer
|
GO:0001704 |
24 |
0.098
|
Zebrafish Mouse |
|
|
regulation of anatomical structure size
|
GO:0090066 |
163 |
0.098
|
|
|
|
nuclear division
|
GO:0000280 |
332 |
0.097
|
Human |
|
|
regulation of tube size
|
GO:0035150 |
46 |
0.096
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
16 |
0.096
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
55 |
0.096
|
|
|
|
oocyte differentiation
|
GO:0009994 |
145 |
0.095
|
|
|
|
protein phosphorylation
|
GO:0006468 |
169 |
0.095
|
Human Mouse |
|
|
wing disc pattern formation
|
GO:0035222 |
66 |
0.094
|
|
|
|
regulation of protein modification process
|
GO:0031399 |
112 |
0.094
|
Human Mouse |
|
|
nephron epithelium morphogenesis
|
GO:0072088 |
3 |
0.093
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
12 |
0.093
|
|
|
|
lipid localization
|
GO:0010876 |
54 |
0.092
|
|
|
|
larval lymph gland hemocyte differentiation
|
GO:0035168 |
11 |
0.092
|
|
|
|
regulation of multicellular organismal development
|
GO:2000026 |
414 |
0.092
|
|
|
|
locomotor rhythm
|
GO:0045475 |
56 |
0.090
|
|
|
|
embryonic development via the syncytial blastoderm
|
GO:0001700 |
148 |
0.088
|
|
|
|
eye antennal disc development
|
GO:0035214 |
60 |
0.088
|
|
|
|
gland development
|
GO:0048732 |
191 |
0.088
|
Mouse |
|
|
negative regulation of cell differentiation
|
GO:0045596 |
143 |
0.087
|
Human Zebrafish Mouse |
|
|
negative regulation of rna biosynthetic process
|
GO:1902679 |
240 |
0.086
|
Human |
|
|
tripartite regional subdivision
|
GO:0007351 |
103 |
0.085
|
|
|
|
chromatin organization
|
GO:0006325 |
207 |
0.085
|
|
|
|
regulation of cell proliferation
|
GO:0042127 |
163 |
0.085
|
Human Mouse |
|
|
wnt signaling pathway
|
GO:0016055 |
98 |
0.084
|
|
|
|
neurological system process
|
GO:0050877 |
358 |
0.084
|
|
|
|
organic substance catabolic process
|
GO:1901575 |
308 |
0.084
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
145 |
0.083
|
Mouse |
|
|
digestive tract morphogenesis
|
GO:0048546 |
127 |
0.083
|
Zebrafish Mouse |
|
|
regulation of phosphorylation
|
GO:0042325 |
147 |
0.082
|
Human Mouse |
|
|
meiotic nuclear division
|
GO:0007126 |
151 |
0.082
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
31 |
0.080
|
|
|
|
response to endogenous stimulus
|
GO:0009719 |
119 |
0.080
|
Human |
|
|
developmental programmed cell death
|
GO:0010623 |
138 |
0.078
|
Mouse |
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
39 |
0.078
|
|
|
|
cell migration involved in gastrulation
|
GO:0042074 |
9 |
0.078
|
|
|
|
morphogenesis of larval imaginal disc epithelium
|
GO:0016335 |
5 |
0.078
|
|
|
|
embryonic organ development
|
GO:0048568 |
50 |
0.076
|
Zebrafish Mouse |
|
|
positive regulation of epithelial cell differentiation
|
GO:0030858 |
1 |
0.076
|
Mouse |
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
59 |
0.075
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
170 |
0.074
|
|
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
24 |
0.074
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
80 |
0.073
|
Human |
|
|
embryonic hemopoiesis
|
GO:0035162 |
26 |
0.073
|
|
|
|
stem cell development
|
GO:0048864 |
79 |
0.072
|
Mouse |
|
|
activin receptor signaling pathway
|
GO:0032924 |
6 |
0.072
|
|
|
|
adherens junction organization
|
GO:0034332 |
27 |
0.072
|
|
|
|
respiratory system development
|
GO:0060541 |
213 |
0.072
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
30 |
0.071
|
|
|
|
positive regulation of stem cell differentiation
|
GO:2000738 |
3 |
0.070
|
|
|
|
cellular protein modification process
|
GO:0006464 |
438 |
0.070
|
Human Mouse |
|
|
response to growth factor
|
GO:0070848 |
31 |
0.070
|
|
|
|
aging
|
GO:0007568 |
143 |
0.069
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
25 |
0.068
|
Human |
|
|
negative regulation of nervous system development
|
GO:0051961 |
92 |
0.068
|
Human Mouse |
|
|
establishment of tissue polarity
|
GO:0007164 |
87 |
0.068
|
|
|
|
protein modification process
|
GO:0036211 |
438 |
0.068
|
Human Mouse |
|
|
negative regulation of notch signaling pathway
|
GO:0045746 |
41 |
0.067
|
Mouse |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
0 |
0.067
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
41 |
0.067
|
Human Mouse |
|
|
protein transport
|
GO:0015031 |
155 |
0.067
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
213 |
0.066
|
Human |
|
|
convergent extension involved in gastrulation
|
GO:0060027 |
2 |
0.065
|
|
|
|
hindgut development
|
GO:0061525 |
58 |
0.065
|
|
|
|
dendrite development
|
GO:0016358 |
204 |
0.065
|
Human |
|
|
oocyte axis specification
|
GO:0007309 |
108 |
0.065
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
45 |
0.065
|
Mouse |
|
|
regulation of intracellular signal transduction
|
GO:1902531 |
236 |
0.065
|
Human Mouse |
|
|
smoothened signaling pathway
|
GO:0007224 |
49 |
0.064
|
|
|
|
gland morphogenesis
|
GO:0022612 |
145 |
0.064
|
Mouse |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
69 |
0.064
|
Human Mouse |
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
79 |
0.063
|
|
|
|
regulation of response to stress
|
GO:0080134 |
200 |
0.062
|
|
|
|
regulation of immune system process
|
GO:0002682 |
176 |
0.061
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
54 |
0.060
|
|
|
|
mesoderm development
|
GO:0007498 |
78 |
0.060
|
Mouse Fly |
|
|
epithelium migration
|
GO:0090132 |
148 |
0.060
|
|
|
|
regulation of transport
|
GO:0051049 |
181 |
0.060
|
|
|
|
regulation of synapse organization
|
GO:0050807 |
110 |
0.059
|
|
|
|
dorsal closure
|
GO:0007391 |
79 |
0.059
|
|
|
|
cell maturation
|
GO:0048469 |
144 |
0.059
|
|
|
|
autophagic vacuole assembly
|
GO:0000045 |
2 |
0.057
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
34 |
0.057
|
Human |
|
|
negative regulation of rna metabolic process
|
GO:0051253 |
251 |
0.057
|
Human |
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
16 |
0.057
|
|
|
|
heart induction
|
GO:0003129 |
3 |
0.057
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
37 |
0.056
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
41 |
0.055
|
|
|
|
positive regulation of nitrogen compound metabolic process
|
GO:0051173 |
354 |
0.055
|
Human Mouse |
|
|
positive regulation of muscle organ development
|
GO:0048636 |
6 |
0.054
|
|
|
|
determination of bilateral symmetry
|
GO:0009855 |
13 |
0.054
|
Zebrafish |
|
|
regulation of cellular component movement
|
GO:0051270 |
42 |
0.053
|
|
|
|
protein complex biogenesis
|
GO:0070271 |
201 |
0.053
|
Zebrafish |
|
|
single organismal cell cell adhesion
|
GO:0016337 |
45 |
0.053
|
Human |
|
|
germ cell migration
|
GO:0008354 |
43 |
0.052
|
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
103 |
0.052
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
65 |
0.052
|
|
|
|
regulation of cellular localization
|
GO:0060341 |
136 |
0.052
|
|
|
|
positive regulation of protein metabolic process
|
GO:0051247 |
128 |
0.052
|
Human Mouse |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
3 |
0.051
|
Human |
|
|
imaginal disc derived wing hair organization
|
GO:0035317 |
45 |
0.051
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
44 |
0.051
|
Human |
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
201 |
0.051
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
0 |
0.051
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
152 |
0.051
|
Mouse |
|
|
positive regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032436 |
19 |
0.051
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
27 |
0.050
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
62 |
0.050
|
|
|
|
organelle fusion
|
GO:0048284 |
46 |
0.049
|
|
|
|
embryonic heart tube development
|
GO:0035050 |
22 |
0.049
|
Zebrafish |
|
|
epithelial cell proliferation
|
GO:0050673 |
15 |
0.049
|
Human Mouse |
|
|
rhythmic behavior
|
GO:0007622 |
76 |
0.049
|
|
|
|
organonitrogen compound metabolic process
|
GO:1901564 |
318 |
0.047
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
83 |
0.047
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
13 |
0.047
|
|
|
|
nephron epithelium development
|
GO:0072009 |
3 |
0.046
|
|
|
|
single organism membrane fusion
|
GO:0044801 |
42 |
0.045
|
|
|
|
positive regulation of developmental growth
|
GO:0048639 |
62 |
0.044
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
47 |
0.044
|
Human Mouse |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
61 |
0.044
|
|
|
|
compound eye photoreceptor cell differentiation
|
GO:0001751 |
140 |
0.044
|
|
|
|
dorsal ventral axis specification
|
GO:0009950 |
66 |
0.044
|
|
|
|
cell fate commitment involved in formation of primary germ layer
|
GO:0060795 |
10 |
0.044
|
Zebrafish |
|
|
regulation of molecular function
|
GO:0065009 |
217 |
0.044
|
Human |
|
|
anterior malpighian tubule development
|
GO:0061327 |
12 |
0.043
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
44 |
0.043
|
|
|
|
hemocyte differentiation
|
GO:0042386 |
38 |
0.043
|
|
|
|
cell fate specification involved in pattern specification
|
GO:0060573 |
8 |
0.043
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
122 |
0.043
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
35 |
0.043
|
|
|
|
regulation of cell death
|
GO:0010941 |
173 |
0.043
|
Human Mouse |
|
|
photoreceptor cell maintenance
|
GO:0045494 |
11 |
0.043
|
|
|
|
organic acid metabolic process
|
GO:0006082 |
103 |
0.042
|
|
|
|
apoptotic process
|
GO:0006915 |
159 |
0.041
|
Mouse |
|
|
camera type eye development
|
GO:0043010 |
4 |
0.041
|
Mouse |
|
|
imaginal disc derived wing margin morphogenesis
|
GO:0008587 |
41 |
0.041
|
|
|
|
negative regulation of bmp signaling pathway
|
GO:0030514 |
12 |
0.040
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
31 |
0.039
|
|
|
|
nephron morphogenesis
|
GO:0072028 |
3 |
0.039
|
Mouse |
|
|
macromolecular complex assembly
|
GO:0065003 |
256 |
0.039
|
Zebrafish |
|
|
cell proliferation involved in imaginal disc derived wing morphogenesis
|
GO:0090255 |
2 |
0.039
|
|
|
|
cell cell signaling involved in cell fate commitment
|
GO:0045168 |
210 |
0.039
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
34 |
0.038
|
|
|
|
regulation of circadian rhythm
|
GO:0042752 |
49 |
0.038
|
|
|
|
regulation of mitosis
|
GO:0007088 |
56 |
0.038
|
Human |
|
|
larval development
|
GO:0002164 |
104 |
0.037
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
78 |
0.037
|
|
|
|
regulation of protein stability
|
GO:0031647 |
43 |
0.036
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
0 |
0.036
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
27 |
0.036
|
|
|
|
negative regulation of macromolecule biosynthetic process
|
GO:0010558 |
270 |
0.036
|
Human |
|
|
spinal cord dorsal ventral patterning
|
GO:0021513 |
1 |
0.035
|
|
|
|
lateral inhibition
|
GO:0046331 |
206 |
0.035
|
|
|
|
cell rearrangement involved in malpighian tubule morphogenesis
|
GO:0061334 |
3 |
0.035
|
|
|
|
detection of stimulus
|
GO:0051606 |
156 |
0.035
|
|
|
|
lymph gland development
|
GO:0048542 |
28 |
0.035
|
|
|
|
transmembrane transport
|
GO:0055085 |
139 |
0.035
|
|
|
|
glandular epithelial cell differentiation
|
GO:0002067 |
1 |
0.034
|
Human |
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
23 |
0.034
|
|
|
|
negative regulation of g1 s transition of mitotic cell cycle
|
GO:2000134 |
13 |
0.034
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
18 |
0.034
|
Human |
|
|
skeletal muscle organ development
|
GO:0060538 |
48 |
0.034
|
|
|
|
spermatid development
|
GO:0007286 |
98 |
0.034
|
|
|
|
spermatid differentiation
|
GO:0048515 |
114 |
0.034
|
|
|
|
positive regulation of protein import into nucleus
|
GO:0042307 |
21 |
0.033
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
95 |
0.033
|
|
|
|
positive regulation of cellular protein catabolic process
|
GO:1903364 |
24 |
0.033
|
|
|
|
regulation of protein localization
|
GO:0032880 |
76 |
0.032
|
|
|
|
cell fate commitment involved in pattern specification
|
GO:0060581 |
31 |
0.032
|
|
|
|
protein maturation
|
GO:0051604 |
71 |
0.032
|
|
|
|
embryonic hindgut morphogenesis
|
GO:0048619 |
48 |
0.032
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
196 |
0.032
|
Human |
|
|
regulation of cell fate specification
|
GO:0042659 |
27 |
0.032
|
Zebrafish |
|
|
cellular homeostasis
|
GO:0019725 |
80 |
0.032
|
Mouse |
|
|
positive regulation of cell differentiation
|
GO:0045597 |
64 |
0.032
|
Human Mouse |
|
|
neurotransmitter transport
|
GO:0006836 |
37 |
0.032
|
|
|
|
regulation of cellular protein metabolic process
|
GO:0032268 |
243 |
0.031
|
Human Mouse |
|
|
cuticle development
|
GO:0042335 |
86 |
0.031
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
4 |
0.031
|
|
|
|
cell adhesion
|
GO:0007155 |
136 |
0.031
|
Human |
|
|
dendrite morphogenesis
|
GO:0048813 |
199 |
0.031
|
|
|
|
non sensory hair organization
|
GO:0035316 |
47 |
0.031
|
|
|
|
regulation of behavior
|
GO:0050795 |
75 |
0.030
|
|
|
|
positive regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903052 |
24 |
0.030
|
|
|
|
chromosome segregation
|
GO:0007059 |
157 |
0.030
|
|
|
|
positive regulation of rna biosynthetic process
|
GO:1902680 |
266 |
0.030
|
Human Mouse |
|
|
secretion by cell
|
GO:0032940 |
101 |
0.030
|
|
|
|
regulation of catabolic process
|
GO:0009894 |
170 |
0.030
|
|
|
|
negative regulation of transcription dna templated
|
GO:0045892 |
237 |
0.030
|
Human |
|
|
positive regulation of cell motility
|
GO:2000147 |
3 |
0.030
|
|
|
|
reproductive system development
|
GO:0061458 |
74 |
0.030
|
Mouse Fly |
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
10 |
0.030
|
|
|
|
lipid metabolic process
|
GO:0006629 |
121 |
0.030
|
Human |
|
|
tissue homeostasis
|
GO:0001894 |
36 |
0.030
|
|
|
|
formation of anatomical boundary
|
GO:0048859 |
37 |
0.030
|
|
|
|
cell cycle arrest
|
GO:0007050 |
4 |
0.030
|
|
|
|
zygotic determination of anterior posterior axis embryo
|
GO:0007354 |
27 |
0.030
|
|
|
|
regulation of imaginal disc growth
|
GO:0045570 |
26 |
0.029
|
|
|
|
positive regulation of protein localization to plasma membrane
|
GO:1903078 |
3 |
0.029
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
21 |
0.029
|
|
|
|
negative regulation of synaptic growth at neuromuscular junction
|
GO:0045886 |
39 |
0.029
|
|
|
|
eye antennal disc morphogenesis
|
GO:0007455 |
34 |
0.029
|
|
|
|
cell growth
|
GO:0016049 |
108 |
0.029
|
|
|
|
positive regulation of transport
|
GO:0051050 |
92 |
0.029
|
|
|
|
immune system development
|
GO:0002520 |
57 |
0.028
|
|
|
|
circadian behavior
|
GO:0048512 |
76 |
0.028
|
|
|
|
biological adhesion
|
GO:0022610 |
138 |
0.028
|
Human |
|
|
organic substance transport
|
GO:0071702 |
257 |
0.028
|
Human |
|
|
defense response
|
GO:0006952 |
300 |
0.028
|
Mouse |
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
136 |
0.027
|
|
|
|
cell cell junction organization
|
GO:0045216 |
55 |
0.027
|
|
|
|
response to hexose
|
GO:0009746 |
3 |
0.027
|
|
|
|
negative regulation of cell cell adhesion
|
GO:0022408 |
8 |
0.027
|
|
|
|
vesicle localization
|
GO:0051648 |
55 |
0.027
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
140 |
0.026
|
|
|
|
positive regulation of cellular protein metabolic process
|
GO:0032270 |
118 |
0.026
|
Human Mouse |
|
|
reproductive behavior
|
GO:0019098 |
122 |
0.026
|
|
|
|
muscle tissue morphogenesis
|
GO:0060415 |
2 |
0.026
|
|
|
|
hindbrain development
|
GO:0030902 |
2 |
0.026
|
|
|
|
regulation of protein phosphorylation
|
GO:0001932 |
64 |
0.025
|
Human Mouse |
|
|
organ induction
|
GO:0001759 |
3 |
0.025
|
|
|
|
circadian rhythm
|
GO:0007623 |
105 |
0.025
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
161 |
0.025
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
82 |
0.025
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
65 |
0.025
|
|
|
|
negative regulation of neuron differentiation
|
GO:0045665 |
16 |
0.024
|
Human Mouse |
|
|
development of primary sexual characteristics
|
GO:0045137 |
50 |
0.024
|
Fly |
|
|
positive regulation of rna metabolic process
|
GO:0051254 |
271 |
0.024
|
Human Mouse |
|
|
regulation of cell adhesion
|
GO:0030155 |
27 |
0.024
|
Human |
|
|
detection of light stimulus involved in visual perception
|
GO:0050908 |
6 |
0.024
|
|
