Drosophila melanogaster

117 known processes

ken (Dmel_CG5575)

ken and barbie

(Aliases: 5029,KEN,3907,ok,8253,Ken,Dmel\CG5575,l(2)05029,P420,BCL-6/KEN,l(2)02970,okina,2970,l(2)00628,CG5575)

ken biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell migration GO:0016477 238 0.694
sodium dependent phosphate transport GO:0044341 2 0.501
wing disc morphogenesis GO:0007472 344 0.440
localization of cell GO:0051674 257 0.343
cell motility GO:0048870 251 0.318
transcription from rna polymerase ii promoter GO:0006366 368 0.300
purine ribonucleoside metabolic process GO:0046128 127 0.286
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.278
nucleotide metabolic process GO:0009117 161 0.266
purine nucleoside triphosphate metabolic process GO:0009144 119 0.262
ribonucleoside triphosphate catabolic process GO:0009203 108 0.256
purine ribonucleotide catabolic process GO:0009154 109 0.252
single organism behavior GO:0044708 391 0.240
cellular protein modification process GO:0006464 438 0.237
eye photoreceptor cell development GO:0042462 81 0.229
imaginal disc derived appendage development GO:0048737 399 0.217
olfactory behavior GO:0042048 97 0.206
ameboidal type cell migration GO:0001667 151 0.185
axonogenesis GO:0007409 290 0.180
ovarian follicle cell development GO:0030707 248 0.177
imaginal disc derived wing morphogenesis GO:0007476 337 0.176
single organism cellular localization GO:1902580 180 0.172
carbohydrate derivative metabolic process GO:1901135 217 0.170
purine nucleoside metabolic process GO:0042278 127 0.169
gtp metabolic process GO:0046039 72 0.168
ribonucleoside metabolic process GO:0009119 127 0.168
mesoderm development GO:0007498 78 0.166
purine nucleotide catabolic process GO:0006195 109 0.155
appendage development GO:0048736 401 0.148
nucleoside phosphate catabolic process GO:1901292 110 0.146
regionalization GO:0003002 416 0.145
carbohydrate derivative catabolic process GO:1901136 118 0.145
regulation of catalytic activity GO:0050790 185 0.144
nucleoside catabolic process GO:0009164 112 0.141
gene silencing GO:0016458 138 0.140
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.136
small gtpase mediated signal transduction GO:0007264 88 0.132
nucleoside triphosphate metabolic process GO:0009141 120 0.130
purine nucleoside catabolic process GO:0006152 112 0.128
glycosyl compound catabolic process GO:1901658 112 0.127
positive regulation of gtp catabolic process GO:0033126 43 0.126
guanosine containing compound catabolic process GO:1901069 74 0.123
regulation of ras gtpase activity GO:0032318 38 0.120
nucleoside phosphate metabolic process GO:0006753 162 0.119
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.116
purine ribonucleoside catabolic process GO:0046130 112 0.116
positive regulation of gtpase activity GO:0043547 43 0.114
ribonucleoside triphosphate metabolic process GO:0009199 119 0.111
guanosine containing compound metabolic process GO:1901068 74 0.105
single organism intracellular transport GO:1902582 207 0.105
defense response GO:0006952 300 0.105
sensory organ morphogenesis GO:0090596 260 0.103
photoreceptor cell development GO:0042461 96 0.102
imaginal disc derived appendage morphogenesis GO:0035114 395 0.102
ovarian follicle cell migration GO:0007297 121 0.101
purine nucleoside triphosphate catabolic process GO:0009146 108 0.099
axon development GO:0061564 297 0.096
catabolic process GO:0009056 409 0.095
negative regulation of epithelial cell proliferation GO:0050680 4 0.092
aromatic compound catabolic process GO:0019439 166 0.086
central nervous system development GO:0007417 201 0.085
nucleoside metabolic process GO:0009116 127 0.083
appendage morphogenesis GO:0035107 397 0.083
purine containing compound catabolic process GO:0072523 112 0.082
nucleotide catabolic process GO:0009166 109 0.079
ribonucleotide catabolic process GO:0009261 109 0.075
heart development GO:0007507 82 0.075
phosphate ion transport GO:0006817 4 0.074
immune system process GO:0002376 347 0.074
cellular nitrogen compound catabolic process GO:0044270 165 0.073
response to abiotic stimulus GO:0009628 341 0.071
photoreceptor cell differentiation GO:0046530 170 0.071
purine ribonucleotide metabolic process GO:0009150 145 0.070
intracellular transport GO:0046907 228 0.070
nucleoside triphosphate catabolic process GO:0009143 108 0.070
neuron projection guidance GO:0097485 241 0.068
intracellular signal transduction GO:0035556 300 0.066
organonitrogen compound metabolic process GO:1901564 318 0.066
embryonic pattern specification GO:0009880 174 0.065
sulfur compound metabolic process GO:0006790 59 0.065
neurological system process GO:0050877 358 0.064
positive regulation of phosphorus metabolic process GO:0010562 139 0.063
epithelial cell differentiation GO:0030855 322 0.063
nucleobase containing compound catabolic process GO:0034655 165 0.063
positive regulation of nucleoside metabolic process GO:0045979 47 0.063
small molecule metabolic process GO:0044281 305 0.062
positive regulation of phosphate metabolic process GO:0045937 139 0.062
epithelial cell migration GO:0010631 148 0.062
membrane organization GO:0061024 112 0.062
ribose phosphate metabolic process GO:0019693 145 0.061
single organism catabolic process GO:0044712 228 0.061
nucleobase containing small molecule metabolic process GO:0055086 174 0.060
purine nucleoside monophosphate metabolic process GO:0009126 50 0.060
negative regulation of gene expression GO:0010629 387 0.059
ribonucleoside catabolic process GO:0042454 112 0.058
cellular catabolic process GO:0044248 372 0.058
embryonic morphogenesis GO:0048598 206 0.058
response to other organism GO:0051707 293 0.056
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.055
regulation of localization GO:0032879 275 0.055
vesicle organization GO:0016050 44 0.054
glycosyl compound metabolic process GO:1901657 127 0.053
regulation of cell migration GO:0030334 22 0.052
cell projection assembly GO:0030031 94 0.052
imaginal disc derived wing hair organization GO:0035317 45 0.052
epithelium migration GO:0090132 148 0.051
positive regulation of ras gtpase activity GO:0032320 36 0.051
anterior posterior pattern specification GO:0009952 136 0.051
eye photoreceptor cell differentiation GO:0001754 145 0.050
compound eye photoreceptor development GO:0042051 78 0.050
cellular response to organic substance GO:0071310 132 0.048
molting cycle chitin based cuticle GO:0007591 56 0.048
protein localization to organelle GO:0033365 82 0.047
regulation of epithelial cell proliferation GO:0050678 4 0.047
death GO:0016265 284 0.046
regulation of gtp catabolic process GO:0033124 44 0.046
hematopoietic or lymphoid organ development GO:0048534 57 0.046
response to radiation GO:0009314 155 0.045
post embryonic appendage morphogenesis GO:0035120 385 0.045
regulation of nucleotide metabolic process GO:0006140 62 0.044
protein targeting GO:0006605 64 0.044
organophosphate catabolic process GO:0046434 112 0.044
eye development GO:0001654 323 0.044
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.043
telencephalon development GO:0021537 2 0.043
anterior posterior axis specification GO:0009948 109 0.043
negative regulation of cell death GO:0060548 81 0.043
eye pigmentation GO:0048069 43 0.042
regulation of nucleoside metabolic process GO:0009118 50 0.042
embryo development ending in birth or egg hatching GO:0009792 152 0.042
establishment of localization in cell GO:0051649 402 0.042
sister chromatid segregation GO:0000819 92 0.042
protein modification process GO:0036211 438 0.041
gene silencing by rna GO:0031047 57 0.041
cellular amino acid metabolic process GO:0006520 61 0.041
positive regulation of hydrolase activity GO:0051345 78 0.041
regulation of small gtpase mediated signal transduction GO:0051056 93 0.041
tripartite regional subdivision GO:0007351 103 0.041
regulation of anatomical structure size GO:0090066 163 0.040
tube development GO:0035295 244 0.040
positive regulation of catalytic activity GO:0043085 118 0.039
organonitrogen compound catabolic process GO:1901565 128 0.039
segmentation GO:0035282 207 0.038
regulation of hydrolase activity GO:0051336 97 0.038
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.038
purine containing compound metabolic process GO:0072521 155 0.037
regulation of cellular catabolic process GO:0031329 157 0.037
multi multicellular organism process GO:0044706 123 0.037
chemotaxis GO:0006935 249 0.036
organic substance catabolic process GO:1901575 308 0.036
regulation of phosphate metabolic process GO:0019220 210 0.036
positive regulation of rab gtpase activity GO:0032851 7 0.036
anterior posterior axis specification embryo GO:0008595 103 0.035
response to fungus GO:0009620 50 0.035
border follicle cell migration GO:0007298 113 0.034
tissue migration GO:0090130 155 0.034
columnar cuboidal epithelial cell development GO:0002066 249 0.034
cellular response to dna damage stimulus GO:0006974 223 0.034
imaginal disc derived leg morphogenesis GO:0007480 80 0.033
compound eye development GO:0048749 307 0.033
digestive tract development GO:0048565 149 0.033
positive regulation of cellular component biogenesis GO:0044089 80 0.032
cilium morphogenesis GO:0060271 39 0.032
cellular response to nutrient levels GO:0031669 62 0.032
protein maturation GO:0051604 71 0.032
cellular protein localization GO:0034613 160 0.032
dendrite development GO:0016358 204 0.032
regulation of purine nucleotide catabolic process GO:0033121 48 0.032
response to external biotic stimulus GO:0043207 293 0.032
response to oxygen containing compound GO:1901700 200 0.031
positive regulation of nucleotide metabolic process GO:0045981 55 0.031
axon guidance GO:0007411 233 0.030
carboxylic acid metabolic process GO:0019752 92 0.030
regulation of neuron differentiation GO:0045664 103 0.030
regulation of cellular component biogenesis GO:0044087 201 0.030
oocyte microtubule cytoskeleton organization GO:0016325 35 0.030
negative regulation of signaling GO:0023057 219 0.030
cuticle pigmentation GO:0048067 22 0.029
positive regulation of cell migration GO:0030335 2 0.029
molting cycle process GO:0022404 29 0.029
defense response to other organism GO:0098542 225 0.028
defense response to bacterium GO:0042742 178 0.028
response to biotic stimulus GO:0009607 294 0.028
genitalia morphogenesis GO:0035112 16 0.028
ocellus pigmentation GO:0033060 19 0.028
reproductive structure development GO:0048608 74 0.028
exocrine system development GO:0035272 162 0.027
response to ecdysone GO:0035075 34 0.027
wnt signaling pathway GO:0016055 98 0.027
digestive tract morphogenesis GO:0048546 127 0.027
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.027
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.027
positive regulation of cellular catabolic process GO:0031331 95 0.027
positive regulation of molecular function GO:0044093 136 0.027
oxoacid metabolic process GO:0043436 103 0.027
cellular macromolecule localization GO:0070727 220 0.027
immune system development GO:0002520 57 0.027
organic cyclic compound catabolic process GO:1901361 168 0.027
regulation of cell motility GO:2000145 23 0.027
regulation of protein metabolic process GO:0051246 256 0.026
nitrogen compound transport GO:0071705 85 0.026
locomotory behavior GO:0007626 176 0.026
positive regulation of cell motility GO:2000147 3 0.026
tissue death GO:0016271 102 0.026
regulation of cell cycle GO:0051726 291 0.026
regulation of phosphorus metabolic process GO:0051174 210 0.026
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.026
response to wounding GO:0009611 94 0.026
positive regulation of cellular component organization GO:0051130 156 0.026
organophosphate metabolic process GO:0019637 195 0.025
somatic muscle development GO:0007525 66 0.025
purine nucleotide metabolic process GO:0006163 146 0.025
ribonucleoside monophosphate catabolic process GO:0009158 39 0.025
phosphorylation GO:0016310 294 0.025
organelle assembly GO:0070925 198 0.025
developmental programmed cell death GO:0010623 138 0.024
intracellular protein transport GO:0006886 104 0.024
reproductive system development GO:0061458 74 0.024
leg disc development GO:0035218 92 0.024
tissue morphogenesis GO:0048729 297 0.024
ribonucleotide metabolic process GO:0009259 145 0.024
cell competition in a multicellular organism GO:0035212 10 0.023
camera type eye development GO:0043010 4 0.023
protein ubiquitination GO:0016567 70 0.023
hair cell differentiation GO:0035315 47 0.023
larval development GO:0002164 104 0.023
male genitalia development GO:0030539 19 0.023
cuticle pattern formation GO:0035017 27 0.022
mitotic cell cycle embryonic GO:0045448 38 0.022
heterocycle catabolic process GO:0046700 166 0.022
muscle organ development GO:0007517 127 0.022
larval somatic muscle development GO:0007526 19 0.022
germarium derived egg chamber formation GO:0007293 101 0.022
regulation of ras protein signal transduction GO:0046578 93 0.022
neuron recognition GO:0008038 101 0.022
embryonic hemopoiesis GO:0035162 26 0.022
gtp catabolic process GO:0006184 72 0.022
mitotic spindle organization GO:0007052 220 0.022
negative regulation of response to stimulus GO:0048585 258 0.022
atp metabolic process GO:0046034 49 0.022
single organism membrane organization GO:0044802 93 0.022
histolysis GO:0007559 102 0.022
chaeta development GO:0022416 97 0.021
regulation of rab gtpase activity GO:0032313 7 0.021
dorsal ventral pattern formation GO:0009953 133 0.021
gastrulation GO:0007369 70 0.021
positive regulation of phosphorylation GO:0042327 87 0.021
positive regulation of nucleic acid templated transcription GO:1903508 266 0.021
positive regulation of cellular biosynthetic process GO:0031328 316 0.021
cell death GO:0008219 279 0.021
regulation of intracellular signal transduction GO:1902531 236 0.021
eye antennal disc development GO:0035214 60 0.020
regulation of nucleotide catabolic process GO:0030811 48 0.020
spinal cord development GO:0021510 1 0.020
regulation of gene silencing GO:0060968 63 0.020
cellular amine metabolic process GO:0044106 12 0.020
regulation of purine nucleotide metabolic process GO:1900542 62 0.020
positive regulation of biosynthetic process GO:0009891 316 0.020
response to organic substance GO:0010033 284 0.020
imaginal disc pattern formation GO:0007447 91 0.020
embryonic axis specification GO:0000578 107 0.020
histone ubiquitination GO:0016574 4 0.020
phagocytosis GO:0006909 215 0.020
male courtship behavior veined wing extension GO:0048065 22 0.019
response to sterol GO:0036314 34 0.019
regulation of multicellular organismal development GO:2000026 414 0.019
tube morphogenesis GO:0035239 191 0.019
single organism cell adhesion GO:0098602 47 0.019
leg disc morphogenesis GO:0007478 80 0.019
respiratory system development GO:0060541 213 0.018
organic substance transport GO:0071702 257 0.018
atp catabolic process GO:0006200 38 0.018
purine nucleoside monophosphate catabolic process GO:0009128 38 0.018
vesicle mediated transport GO:0016192 381 0.018
protein localization GO:0008104 284 0.018
camera type eye morphogenesis GO:0048593 2 0.018
gland development GO:0048732 191 0.018
regulation of cellular component movement GO:0051270 42 0.018
sterol homeostasis GO:0055092 4 0.018
nucleoside monophosphate catabolic process GO:0009125 39 0.018
protein transport GO:0015031 155 0.017
sex differentiation GO:0007548 81 0.017
regulation of nervous system development GO:0051960 248 0.017
regulation of immune system process GO:0002682 176 0.017
digestive system development GO:0055123 149 0.017
adult behavior GO:0030534 137 0.017
chromatin modification GO:0016568 147 0.017
renal system development GO:0072001 72 0.017
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.017
homeostatic process GO:0042592 199 0.017
cell recognition GO:0008037 102 0.017
epithelial cell proliferation GO:0050673 15 0.017
brain development GO:0007420 120 0.017
regulation of molecular function GO:0065009 217 0.017
imaginal disc derived female genitalia development GO:0007486 6 0.016
ras protein signal transduction GO:0007265 88 0.016
epithelial tube morphogenesis GO:0060562 88 0.016
developmental pigmentation GO:0048066 68 0.016
positive regulation of nucleotide catabolic process GO:0030813 46 0.016
regulation of cellular amine metabolic process GO:0033238 3 0.016
positive regulation of neurogenesis GO:0050769 41 0.016
salivary gland histolysis GO:0035070 88 0.016
intracellular protein transmembrane transport GO:0065002 4 0.016
regulation of protein modification process GO:0031399 112 0.015
growth GO:0040007 359 0.015
dorsal trunk growth open tracheal system GO:0035001 7 0.015
multicellular organismal reproductive behavior GO:0033057 110 0.015
skin development GO:0043588 65 0.015
wound healing GO:0042060 75 0.015
male gamete generation GO:0048232 201 0.015
regulation of mitotic cell cycle GO:0007346 190 0.015
regulation of locomotion GO:0040012 42 0.015
positive regulation of gene expression GO:0010628 290 0.015
negative regulation of programmed cell death GO:0043069 72 0.015
regulation of imaginal disc derived wing size GO:0044719 20 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
regulation of cellular component size GO:0032535 98 0.015
developmental growth involved in morphogenesis GO:0060560 65 0.015
mating GO:0007618 120 0.014
cellular response to organonitrogen compound GO:0071417 36 0.014
response to organophosphorus GO:0046683 2 0.014
negative regulation of cell communication GO:0010648 223 0.014
dendrite morphogenesis GO:0048813 199 0.014
chitin based cuticle sclerotization GO:0007593 19 0.014
taxis GO:0042330 304 0.014
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.014
chromosome organization GO:0051276 360 0.014
macromolecule catabolic process GO:0009057 161 0.014
positive regulation of catabolic process GO:0009896 105 0.014
protein modification by small protein conjugation GO:0032446 79 0.014
blastoderm segmentation GO:0007350 159 0.014
negative regulation of cell differentiation GO:0045596 143 0.014
regulation of cellular protein metabolic process GO:0032268 243 0.013
regulation of neurogenesis GO:0050767 158 0.013
establishment of protein localization GO:0045184 163 0.013
rab protein signal transduction GO:0032482 6 0.013
regulation of cell differentiation GO:0045595 302 0.013
response to alcohol GO:0097305 95 0.013
pigmentation GO:0043473 75 0.013
segment specification GO:0007379 33 0.013
periodic partitioning GO:0007365 29 0.013
endocytosis GO:0006897 310 0.013
regulation of cell size GO:0008361 63 0.013
regulation of catabolic process GO:0009894 170 0.013
immune response GO:0006955 246 0.013
enzyme linked receptor protein signaling pathway GO:0007167 179 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 38 0.013
positive regulation of rho gtpase activity GO:0032321 19 0.013
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 4 0.013
regulation of cell projection organization GO:0031344 92 0.013
cell junction organization GO:0034330 57 0.013
pigment metabolic process GO:0042440 84 0.012
cellular component assembly involved in morphogenesis GO:0010927 151 0.012
cytoplasmic transport GO:0016482 130 0.012
gland morphogenesis GO:0022612 145 0.012
dorsal ventral pattern formation imaginal disc GO:0007450 51 0.012
positive regulation of protein phosphorylation GO:0001934 34 0.012
urogenital system development GO:0001655 72 0.012
imaginal disc derived wing vein specification GO:0007474 48 0.012
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.012
response to axon injury GO:0048678 12 0.012
autophagic cell death GO:0048102 83 0.012
negative regulation of nucleic acid templated transcription GO:1903507 240 0.012
positive regulation of transferase activity GO:0051347 26 0.012
mapk cascade GO:0000165 107 0.012
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
cell cell junction organization GO:0045216 55 0.012
wing disc pattern formation GO:0035222 66 0.012
hemopoiesis GO:0030097 46 0.012
epithelial cell development GO:0002064 274 0.012
eye pigment biosynthetic process GO:0006726 32 0.012
regulation of embryonic development GO:0045995 68 0.012
chaeta morphogenesis GO:0008407 42 0.011
extrinsic apoptotic signaling pathway GO:0097191 1 0.011
substrate dependent cell migration GO:0006929 3 0.011
mitotic sister chromatid segregation GO:0000070 87 0.011
substrate adhesion dependent cell spreading GO:0034446 2 0.011
spermatogenesis GO:0007283 200 0.011
cell cycle phase transition GO:0044770 140 0.011
ocellus pigment metabolic process GO:0046158 19 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.011
protein processing GO:0016485 68 0.011
eye pigment metabolic process GO:0042441 33 0.011
retina development in camera type eye GO:0060041 4 0.011
eye morphogenesis GO:0048592 260 0.011
regulation of endocytosis GO:0030100 37 0.011
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.011
mushroom body development GO:0016319 70 0.011
stem cell differentiation GO:0048863 117 0.011
ion transport GO:0006811 145 0.011
jnk cascade GO:0007254 50 0.011
single organism biosynthetic process GO:0044711 206 0.011
secretion by cell GO:0032940 101 0.011
regulation of rab protein signal transduction GO:0032483 7 0.011
regulation of cell cycle process GO:0010564 181 0.011
response to lipopolysaccharide GO:0032496 4 0.010
regulation of cell junction assembly GO:1901888 2 0.010
kidney development GO:0001822 3 0.010
protein modification by small protein conjugation or removal GO:0070647 106 0.010
embryonic organ development GO:0048568 50 0.010
protein localization to membrane GO:0072657 19 0.010
striated muscle tissue development GO:0014706 27 0.010
positive regulation of protein kinase activity GO:0045860 25 0.010
regulation of neuron projection development GO:0010975 69 0.010
cellular response to external stimulus GO:0071496 66 0.010
cellular macromolecule catabolic process GO:0044265 136 0.010
body morphogenesis GO:0010171 2 0.010

ken disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.067
nervous system disease DOID:863 0 0.067
sensory system disease DOID:0050155 0 0.030
auditory system disease DOID:2742 0 0.014
nonsyndromic deafness DOID:0050563 0 0.014
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012