Drosophila melanogaster

55 known processes

CYLD (Dmel_CG5603)

cylindromatosis

(Aliases: dCYLD,Dmel\CG5603,CG5603)

CYLD biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.362
regulation of cell differentiation GO:0045595 302 0.338
Mouse
positive regulation of endopeptidase activity GO:0010950 26 0.249
regulation of catabolic process GO:0009894 170 0.246
cellular response to starvation GO:0009267 61 0.238
cellular catabolic process GO:0044248 372 0.227
cellular response to external stimulus GO:0071496 66 0.223
wing disc morphogenesis GO:0007472 344 0.221
regulation of peptidase activity GO:0052547 39 0.211
protein modification by small protein removal GO:0070646 28 0.199
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.172
male gamete generation GO:0048232 201 0.170
response to starvation GO:0042594 97 0.169
response to nutrient levels GO:0031667 114 0.158
response to biotic stimulus GO:0009607 294 0.158
neurological system process GO:0050877 358 0.153
regulation of transport GO:0051049 181 0.151
Human
single organism biosynthetic process GO:0044711 206 0.151
endocytosis GO:0006897 310 0.148
response to other organism GO:0051707 293 0.144
imaginal disc derived wing morphogenesis GO:0007476 337 0.140
regulation of cellular catabolic process GO:0031329 157 0.138
triglyceride metabolic process GO:0006641 12 0.137
regulation of localization GO:0032879 275 0.136
Human
cell division GO:0051301 248 0.133
intracellular signal transduction GO:0035556 300 0.131
aging GO:0007568 143 0.130
homeostatic process GO:0042592 199 0.130
negative regulation of cellular metabolic process GO:0031324 382 0.130
intracellular transport GO:0046907 228 0.128
Human
protein modification by small protein conjugation or removal GO:0070647 106 0.128
cellular response to nutrient levels GO:0031669 62 0.125
positive regulation of cellular biosynthetic process GO:0031328 316 0.123
ribonucleotide metabolic process GO:0009259 145 0.123
cation transport GO:0006812 110 0.122
organic substance catabolic process GO:1901575 308 0.121
spermatogenesis GO:0007283 200 0.120
single organism behavior GO:0044708 391 0.114
regulation of organelle organization GO:0033043 196 0.112
Human
telencephalon development GO:0021537 2 0.111
synaptic transmission GO:0007268 288 0.111
cellular protein modification process GO:0006464 438 0.110
regulation of growth GO:0040008 233 0.109
locomotory behavior GO:0007626 176 0.106
cellular lipid metabolic process GO:0044255 83 0.103
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.102
response to external biotic stimulus GO:0043207 293 0.102
regulation of apoptotic process GO:0042981 130 0.099
Human
response to oxidative stress GO:0006979 86 0.099
protein transport GO:0015031 155 0.097
Human
programmed cell death GO:0012501 257 0.097
Human Mouse
regulation of multi organism process GO:0043900 131 0.097
lipid metabolic process GO:0006629 121 0.095
imaginal disc derived appendage development GO:0048737 399 0.094
vesicle mediated transport GO:0016192 381 0.094
growth GO:0040007 359 0.091
regulation of dendrite development GO:0050773 37 0.089
single organism catabolic process GO:0044712 228 0.088
determination of adult lifespan GO:0008340 137 0.088
cellular response to extracellular stimulus GO:0031668 64 0.088
sperm individualization GO:0007291 48 0.086
response to extracellular stimulus GO:0009991 116 0.086
establishment of localization in cell GO:0051649 402 0.086
Human
axon guidance GO:0007411 233 0.079
catabolic process GO:0009056 409 0.078
negative regulation of developmental process GO:0051093 201 0.078
Mouse
protein modification process GO:0036211 438 0.077
purine ribonucleotide metabolic process GO:0009150 145 0.077
organonitrogen compound metabolic process GO:1901564 318 0.075
developmental growth GO:0048589 280 0.075
sensory organ morphogenesis GO:0090596 260 0.075
organophosphate biosynthetic process GO:0090407 46 0.075
organophosphate metabolic process GO:0019637 195 0.074
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.074
regulation of proteolysis GO:0030162 87 0.073
regulation of molecular function GO:0065009 217 0.073
Human
positive regulation of macromolecule metabolic process GO:0010604 405 0.073
forebrain development GO:0030900 2 0.072
death GO:0016265 284 0.072
Human Mouse
negative regulation of cell communication GO:0010648 223 0.071
Human
negative regulation of gene expression GO:0010629 387 0.070
regulation of intracellular signal transduction GO:1902531 236 0.067
Human
regulation of protein metabolic process GO:0051246 256 0.066
regulation of multicellular organismal development GO:2000026 414 0.066
Mouse
circadian rhythm GO:0007623 105 0.065
appendage morphogenesis GO:0035107 397 0.063
regulation of synaptic transmission GO:0050804 69 0.063
regulation of cell development GO:0060284 215 0.063
triglyceride biosynthetic process GO:0019432 2 0.063
negative regulation of growth GO:0045926 84 0.063
response to bacterium GO:0009617 198 0.063
taxis GO:0042330 304 0.063
glycosyl compound metabolic process GO:1901657 127 0.062
apoptotic process GO:0006915 159 0.060
Human
regulation of cellular component biogenesis GO:0044087 201 0.060
positive regulation of developmental process GO:0051094 143 0.060
neuron projection extension GO:1990138 32 0.060
neuron projection guidance GO:0097485 241 0.058
positive regulation of gene expression GO:0010628 290 0.057
chaeta development GO:0022416 97 0.057
nucleotide metabolic process GO:0009117 161 0.056
positive regulation of nucleic acid templated transcription GO:1903508 266 0.056
positive regulation of rna biosynthetic process GO:1902680 266 0.055
response to oxygen containing compound GO:1901700 200 0.054
positive regulation of catabolic process GO:0009896 105 0.054
axon development GO:0061564 297 0.053
response to organic substance GO:0010033 284 0.053
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.052
cell death GO:0008219 279 0.051
Human Mouse
response to endogenous stimulus GO:0009719 119 0.050
positive regulation of cellular catabolic process GO:0031331 95 0.050
transcription from rna polymerase ii promoter GO:0006366 368 0.050
tissue morphogenesis GO:0048729 297 0.050
single organism cellular localization GO:1902580 180 0.049
Human
regulation of synapse organization GO:0050807 110 0.049
negative regulation of transcription dna templated GO:0045892 237 0.048
regulation of anatomical structure morphogenesis GO:0022603 242 0.048
eye morphogenesis GO:0048592 260 0.048
acylglycerol biosynthetic process GO:0046463 2 0.047
positive regulation of proteolysis GO:0045862 52 0.047
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.047
immune response GO:0006955 246 0.046
developmental growth involved in morphogenesis GO:0060560 65 0.046
response to organonitrogen compound GO:0010243 75 0.046
imaginal disc derived appendage morphogenesis GO:0035114 395 0.045
chromatin organization GO:0006325 207 0.045
regulation of synapse structure and activity GO:0050803 128 0.045
dendrite morphogenesis GO:0048813 199 0.044
single organism intracellular transport GO:1902582 207 0.044
Human
nucleobase containing small molecule metabolic process GO:0055086 174 0.043
lipid homeostasis GO:0055088 33 0.043
axonogenesis GO:0007409 290 0.042
regulation of ras protein signal transduction GO:0046578 93 0.042
cell migration GO:0016477 238 0.042
establishment of protein localization GO:0045184 163 0.042
Human
regulation of cellular component size GO:0032535 98 0.042
immune system process GO:0002376 347 0.042
Mouse
nucleoside catabolic process GO:0009164 112 0.041
protein catabolic process GO:0030163 101 0.041
multicellular organismal aging GO:0010259 140 0.041
regulation of vesicle mediated transport GO:0060627 59 0.041
regulation of developmental growth GO:0048638 174 0.040
small molecule metabolic process GO:0044281 305 0.040
glycosyl compound catabolic process GO:1901658 112 0.040
nucleocytoplasmic transport GO:0006913 72 0.040
Human
ribose phosphate metabolic process GO:0019693 145 0.039
proteolysis GO:0006508 192 0.039
defense response GO:0006952 300 0.039
regulation of dna metabolic process GO:0051052 34 0.039
protein deubiquitination GO:0016579 17 0.038
chemotaxis GO:0006935 249 0.038
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.038
mucosal immune response GO:0002385 10 0.037
cellular response to chemical stimulus GO:0070887 199 0.037
regulation of cellular protein metabolic process GO:0032268 243 0.037
regulation of programmed cell death GO:0043067 152 0.037
Human
regulation of catalytic activity GO:0050790 185 0.037
cellular response to carbon dioxide GO:0071244 2 0.037
regulation of cell death GO:0010941 173 0.036
Human
regulation of antimicrobial humoral response GO:0002759 50 0.036
negative regulation of biosynthetic process GO:0009890 277 0.035
positive regulation of peptidase activity GO:0010952 29 0.035
establishment of vesicle localization GO:0051650 51 0.035
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.035
carbohydrate derivative metabolic process GO:1901135 217 0.035
cytoplasmic transport GO:0016482 130 0.035
Human
positive regulation of transport GO:0051050 92 0.035
positive regulation of response to stimulus GO:0048584 323 0.034
Human
nucleotide catabolic process GO:0009166 109 0.034
protein targeting GO:0006605 64 0.034
Human
regulation of response to stress GO:0080134 200 0.034
purine ribonucleotide catabolic process GO:0009154 109 0.034
regulation of response to external stimulus GO:0032101 115 0.034
mitotic cytokinesis GO:0000281 50 0.033
axon extension GO:0048675 32 0.033
regulation of protein transport GO:0051223 57 0.032
Human
positive regulation of lipid storage GO:0010884 4 0.032
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.032
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress GO:0070059 4 0.032
developmental cell growth GO:0048588 52 0.032
phagocytosis GO:0006909 215 0.031
ribonucleotide catabolic process GO:0009261 109 0.031
phosphorylation GO:0016310 294 0.031
purine containing compound metabolic process GO:0072521 155 0.031
adult behavior GO:0030534 137 0.031
spermatid differentiation GO:0048515 114 0.031
connective tissue development GO:0061448 3 0.031
lipid biosynthetic process GO:0008610 46 0.031
negative regulation of signal transduction GO:0009968 206 0.031
Human
intracellular protein transport GO:0006886 104 0.030
Human
negative regulation of cell death GO:0060548 81 0.030
nucleoside phosphate catabolic process GO:1901292 110 0.030
nucleoside triphosphate catabolic process GO:0009143 108 0.030
chemical homeostasis GO:0048878 92 0.029
negative regulation of rna biosynthetic process GO:1902679 240 0.029
response to lipopolysaccharide GO:0032496 4 0.029
neural retina development GO:0003407 4 0.029
negative regulation of signaling GO:0023057 219 0.029
Human
regulation of intracellular protein transport GO:0033157 46 0.029
Human
ribonucleoside triphosphate catabolic process GO:0009203 108 0.029
purine nucleotide metabolic process GO:0006163 146 0.029
regulation of cell cycle process GO:0010564 181 0.028
single organism membrane organization GO:0044802 93 0.028
anatomical structure homeostasis GO:0060249 97 0.028
cell growth GO:0016049 108 0.028
regulation of lipid storage GO:0010883 22 0.028
carbohydrate derivative catabolic process GO:1901136 118 0.027
purine nucleoside triphosphate metabolic process GO:0009144 119 0.027
wnt signaling pathway GO:0016055 98 0.027
Human
regulation of protein catabolic process GO:0042176 55 0.027
positive regulation of multicellular organismal process GO:0051240 143 0.027
regulation of neurogenesis GO:0050767 158 0.027
negative regulation of programmed cell death GO:0043069 72 0.027
positive regulation of hydrolase activity GO:0051345 78 0.027
defense response to bacterium GO:0042742 178 0.027
cortical cytoskeleton organization GO:0030865 29 0.026
nucleoside triphosphate metabolic process GO:0009141 120 0.026
defense response to other organism GO:0098542 225 0.026
membrane organization GO:0061024 112 0.026
nucleoside phosphate metabolic process GO:0006753 162 0.026
cellular response to abiotic stimulus GO:0071214 58 0.026
neuron remodeling GO:0016322 29 0.026
negative regulation of response to stimulus GO:0048585 258 0.026
Human
developmental programmed cell death GO:0010623 138 0.026
positive regulation of transcription dna templated GO:0045893 266 0.026
nuclear transport GO:0051169 72 0.025
Human
developmental maturation GO:0021700 172 0.025
axon cargo transport GO:0008088 29 0.025
ribonucleoside catabolic process GO:0042454 112 0.025
positive regulation of rna metabolic process GO:0051254 271 0.025
neuromuscular junction development GO:0007528 149 0.025
ribonucleoside triphosphate metabolic process GO:0009199 119 0.025
mitochondrion organization GO:0007005 65 0.025
macromolecule catabolic process GO:0009057 161 0.025
chromosome organization GO:0051276 360 0.025
rhythmic process GO:0048511 106 0.025
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.025
positive regulation of programmed cell death GO:0043068 62 0.025
Human
innate immune response GO:0045087 144 0.024
negative regulation of protein metabolic process GO:0051248 85 0.024
organic substance transport GO:0071702 257 0.024
Human
actin filament based process GO:0030029 220 0.024
positive regulation of protein metabolic process GO:0051247 128 0.024
chromatin modification GO:0016568 147 0.024
cyclic purine nucleotide metabolic process GO:0052652 25 0.024
epidermis development GO:0008544 65 0.024
negative regulation of rna metabolic process GO:0051253 251 0.024
positive regulation of biosynthetic process GO:0009891 316 0.024
morphogenesis of an epithelium GO:0002009 276 0.023
negative regulation of autophagy GO:0010507 16 0.023
cellular macromolecule localization GO:0070727 220 0.023
Human
production of molecular mediator of immune response GO:0002440 46 0.023
regulation of cytoskeleton organization GO:0051493 89 0.023
Human
purine nucleoside triphosphate catabolic process GO:0009146 108 0.023
positive regulation of signal transduction GO:0009967 223 0.023
Human
regulation of circadian sleep wake cycle GO:0042749 25 0.023
regulation of reactive oxygen species metabolic process GO:2000377 8 0.023
regulation of hydrolase activity GO:0051336 97 0.023
response to nitrogen compound GO:1901698 90 0.023
dendrite development GO:0016358 204 0.023
eye development GO:0001654 323 0.023
tissue homeostasis GO:0001894 36 0.023
regulation of anatomical structure size GO:0090066 163 0.022
regulation of endopeptidase activity GO:0052548 36 0.022
segmentation GO:0035282 207 0.022
positive regulation of molecular function GO:0044093 136 0.022
small gtpase mediated signal transduction GO:0007264 88 0.022
nitrogen compound transport GO:0071705 85 0.022
Human
purine nucleoside metabolic process GO:0042278 127 0.022
compound eye retinal cell programmed cell death GO:0046667 23 0.022
positive regulation of cell death GO:0010942 69 0.022
Human
ion transport GO:0006811 145 0.022
acylglycerol homeostasis GO:0055090 19 0.022
regulation of mapk cascade GO:0043408 92 0.022
regulation of cellular localization GO:0060341 136 0.022
Human
imaginal disc derived wing margin morphogenesis GO:0008587 41 0.021
protein localization GO:0008104 284 0.021
Human
regulation of humoral immune response GO:0002920 51 0.021
learning or memory GO:0007611 141 0.021
purine containing compound catabolic process GO:0072523 112 0.021
positive regulation of protein transport GO:0051222 37 0.021
ion homeostasis GO:0050801 55 0.021
regulation of neuron death GO:1901214 26 0.021
negative regulation of apoptotic process GO:0043066 63 0.021
larval feeding behavior GO:0030536 15 0.021
central nervous system development GO:0007417 201 0.021
purine nucleoside catabolic process GO:0006152 112 0.021
positive regulation of cellular protein metabolic process GO:0032270 118 0.021
encapsulation of foreign target GO:0035010 38 0.021
rna localization GO:0006403 115 0.020
organelle fission GO:0048285 340 0.020
cellular protein localization GO:0034613 160 0.020
Human
acylglycerol metabolic process GO:0006639 12 0.020
response to abiotic stimulus GO:0009628 341 0.020
skeletal muscle fiber development GO:0048741 3 0.020
regulation of establishment of protein localization GO:0070201 61 0.020
Human
melanotic encapsulation of foreign target GO:0035011 30 0.020
positive regulation of cell differentiation GO:0045597 64 0.020
cyclic nucleotide biosynthetic process GO:0009190 25 0.019
purine ribonucleoside catabolic process GO:0046130 112 0.019
positive regulation of developmental growth GO:0048639 62 0.019
immune effector process GO:0002252 98 0.019
regulation of autophagy GO:0010506 62 0.019
regulation of response to biotic stimulus GO:0002831 63 0.019
microtubule based transport GO:0010970 42 0.018
protein targeting to nucleus GO:0044744 51 0.018
Human
regulation of nucleocytoplasmic transport GO:0046822 35 0.018
Human
regulation of response to oxidative stress GO:1902882 4 0.018
molting cycle GO:0042303 56 0.018
regulation of cell size GO:0008361 63 0.018
protein import GO:0017038 55 0.018
Human
positive regulation of apoptotic process GO:0043065 47 0.018
Human
actin cytoskeleton organization GO:0030036 206 0.018
post embryonic appendage morphogenesis GO:0035120 385 0.018
detection of light stimulus GO:0009583 58 0.018
ribonucleoside metabolic process GO:0009119 127 0.018
transition metal ion transport GO:0000041 16 0.018
guanosine containing compound catabolic process GO:1901069 74 0.018
negative regulation of nucleic acid templated transcription GO:1903507 240 0.018
gland development GO:0048732 191 0.018
positive regulation of phosphate metabolic process GO:0045937 139 0.018
cytoskeleton dependent cytokinesis GO:0061640 81 0.018
gtp catabolic process GO:0006184 72 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.017
regulation of defense response GO:0031347 102 0.017
oxoacid metabolic process GO:0043436 103 0.017
protein modification by small protein conjugation GO:0032446 79 0.017
camera type eye development GO:0043010 4 0.017
establishment of organelle localization GO:0051656 122 0.017
regulation of protein import into nucleus GO:0042306 28 0.017
Human
regulation of cell proliferation GO:0042127 163 0.017
cellular protein catabolic process GO:0044257 83 0.017
regulation of cellular response to oxidative stress GO:1900407 4 0.017
modification dependent protein catabolic process GO:0019941 78 0.017
regulation of cellular response to stress GO:0080135 89 0.017
molting cycle chitin based cuticle GO:0007591 56 0.017
regulation of cell growth GO:0001558 43 0.016
organophosphate catabolic process GO:0046434 112 0.016
appendage development GO:0048736 401 0.016
purine nucleotide catabolic process GO:0006195 109 0.016
regulation of microtubule based process GO:0032886 49 0.016
Human
secretion GO:0046903 109 0.016
apoptotic cell clearance GO:0043277 14 0.016
peptidyl amino acid modification GO:0018193 105 0.016
localization of cell GO:0051674 257 0.016
regulation of sequestering of triglyceride GO:0010889 3 0.016
negative regulation of cell proliferation GO:0008285 69 0.016
positive regulation of cell development GO:0010720 61 0.016
cell aging GO:0007569 2 0.016
asymmetric protein localization involved in cell fate determination GO:0045167 9 0.016
regulation of transmembrane transport GO:0034762 27 0.016
positive regulation of protein import into nucleus GO:0042307 21 0.016
organonitrogen compound catabolic process GO:1901565 128 0.015
regulation of endocytosis GO:0030100 37 0.015
regulation of neuron projection development GO:0010975 69 0.015
synaptic growth at neuromuscular junction GO:0051124 119 0.015
positive regulation of catalytic activity GO:0043085 118 0.015
microtubule bundle formation GO:0001578 27 0.015
instar larval development GO:0002168 55 0.015
negative regulation of neuron death GO:1901215 18 0.015
spermatid development GO:0007286 98 0.015
salivary gland cell autophagic cell death GO:0035071 83 0.015
nuclear import GO:0051170 51 0.015
Human
macromolecular complex assembly GO:0065003 256 0.015
Mouse
regulation of protein targeting GO:1903533 29 0.015
Human
neuron recognition GO:0008038 101 0.015
protein processing GO:0016485 68 0.014
regulation of cell cycle GO:0051726 291 0.014
Human
chaeta morphogenesis GO:0008407 42 0.014
regulation of wnt signaling pathway GO:0030111 68 0.014
Human
cytoskeleton dependent intracellular transport GO:0030705 44 0.014
macroautophagy GO:0016236 42 0.014
cell fate determination GO:0001709 91 0.014
modification dependent macromolecule catabolic process GO:0043632 79 0.014
regulation of purine nucleotide metabolic process GO:1900542 62 0.014
triglyceride homeostasis GO:0070328 18 0.014
cytokinesis GO:0000910 90 0.014
actin filament organization GO:0007015 126 0.014
non sensory hair organization GO:0035316 47 0.014
jak stat cascade GO:0007259 49 0.014
negative regulation of cellular protein metabolic process GO:0032269 85 0.014
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.014
wound healing spreading of epidermal cells GO:0035313 1 0.014
response to heat GO:0009408 63 0.014
cellular response to heat GO:0034605 24 0.014
regulation of bmp signaling pathway GO:0030510 23 0.014
cellular response to mechanical stimulus GO:0071260 2 0.014
ubiquitin dependent protein catabolic process GO:0006511 78 0.014
organelle localization GO:0051640 148 0.014
phenol containing compound metabolic process GO:0018958 57 0.014
cell proliferation GO:0008283 299 0.014
reactive oxygen species metabolic process GO:0072593 22 0.013
muscle structure development GO:0061061 224 0.013
embryonic pattern specification GO:0009880 174 0.013
chromatin remodeling GO:0006338 72 0.013
neuron maturation GO:0042551 31 0.013
response to radiation GO:0009314 155 0.013
regulation of cellular protein catabolic process GO:1903362 44 0.013
negative regulation of developmental growth GO:0048640 64 0.013
regulation of phosphorus metabolic process GO:0051174 210 0.013
organic acid metabolic process GO:0006082 103 0.013
gtp metabolic process GO:0046039 72 0.013
negative regulation of cellular biosynthetic process GO:0031327 277 0.013
regulation of intracellular transport GO:0032386 64 0.013
Human
cellular response to organic substance GO:0071310 132 0.013
cellular amide metabolic process GO:0043603 80 0.013
multicellular organismal homeostasis GO:0048871 41 0.013
negative regulation of proteolysis GO:0045861 31 0.013
negative regulation of cellular component organization GO:0051129 108 0.013
lipid modification GO:0030258 24 0.013
carbohydrate metabolic process GO:0005975 82 0.013
regulation of small gtpase mediated signal transduction GO:0051056 93 0.013
positive regulation of apoptotic signaling pathway GO:2001235 4 0.013
Human
jnk cascade GO:0007254 50 0.013
cellular response to oxidative stress GO:0034599 28 0.013
cation homeostasis GO:0055080 51 0.013
organelle fusion GO:0048284 46 0.013
stress activated protein kinase signaling cascade GO:0031098 55 0.012
microtubule based movement GO:0007018 51 0.012
regulation of cytoplasmic transport GO:1903649 47 0.012
Human
protein localization to organelle GO:0033365 82 0.012
Human
compound eye morphogenesis GO:0001745 249 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.012
cellular response to oxygen containing compound GO:1901701 79 0.012
imaginal disc derived wing vein specification GO:0007474 48 0.012
single organism carbohydrate metabolic process GO:0044723 72 0.012
regulation of lipid metabolic process GO:0019216 15 0.012
regulation of ion transport GO:0043269 39 0.012
negative regulation of protein processing GO:0010955 31 0.012
cellular lipid catabolic process GO:0044242 16 0.012
response to dsrna GO:0043331 15 0.012
striated muscle cell development GO:0055002 50 0.012
glycerolipid metabolic process GO:0046486 34 0.012
myotube cell development GO:0014904 3 0.012
response to carbon dioxide GO:0010037 4 0.012
motor neuron axon guidance GO:0008045 58 0.012
regulation of epithelial cell differentiation GO:0030856 4 0.012
positive regulation of growth GO:0045927 75 0.012
mapk cascade GO:0000165 107 0.012
inositol lipid mediated signaling GO:0048017 4 0.012
regulation of circadian sleep wake cycle sleep GO:0045187 21 0.012
negative regulation of cell cycle phase transition GO:1901988 103 0.012
activation of cysteine type endopeptidase activity GO:0097202 17 0.012
nf kappab import into nucleus GO:0042348 1 0.012
Human
compound eye development GO:0048749 307 0.012
endocytic recycling GO:0032456 13 0.011
cell cycle checkpoint GO:0000075 95 0.011
positive regulation of endocytosis GO:0045807 22 0.011
regulation of jnk cascade GO:0046328 40 0.011
negative regulation of multicellular organismal process GO:0051241 142 0.011
Mouse
humoral immune response GO:0006959 117 0.011
regulation of cell projection organization GO:0031344 92 0.011
ribonucleoside monophosphate catabolic process GO:0009158 39 0.011
establishment or maintenance of cell polarity GO:0007163 167 0.011
posttranscriptional regulation of gene expression GO:0010608 145 0.011
negative regulation of multi organism process GO:0043901 29 0.011
regulation of response to extracellular stimulus GO:0032104 18 0.011
regulation of neuron differentiation GO:0045664 103 0.011
retina development in camera type eye GO:0060041 4 0.011
salivary gland morphogenesis GO:0007435 145 0.011
cell motility GO:0048870 251 0.011
response to unfolded protein GO:0006986 9 0.011
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.011
regulation of microtubule cytoskeleton organization GO:0070507 41 0.011
Human
response to organic cyclic compound GO:0014070 89 0.011
dopamine receptor signaling pathway GO:0007212 4 0.011
gland morphogenesis GO:0022612 145 0.011
dendritic spine development GO:0060996 4 0.011
nucleobase containing compound catabolic process GO:0034655 165 0.011
positive regulation of signaling GO:0023056 243 0.011
Human
head development GO:0060322 135 0.011
imaginal disc growth GO:0007446 37 0.011
protein localization to nucleus GO:0034504 55 0.011
Human
pigment metabolic process GO:0042440 84 0.011
regulation of chromosome organization GO:0033044 64 0.011
membrane fusion GO:0061025 42 0.011
mesodermal cell migration GO:0008078 7 0.011
phosphatidylinositol mediated signaling GO:0048015 4 0.011
heterocycle catabolic process GO:0046700 166 0.011
regulation of stress activated mapk cascade GO:0032872 41 0.011
negative regulation of response to external stimulus GO:0032102 22 0.011
cellular response to molecule of bacterial origin GO:0071219 3 0.011
ras protein signal transduction GO:0007265 88 0.011
exocrine system development GO:0035272 162 0.011
regulation of cysteine type endopeptidase activity GO:2000116 27 0.010
purine containing compound biosynthetic process GO:0072522 30 0.010
dormancy process GO:0022611 2 0.010
spindle organization GO:0007051 253 0.010
negative regulation of mitotic cell cycle GO:0045930 109 0.010
single organism membrane fusion GO:0044801 42 0.010
melanization defense response GO:0035006 45 0.010

CYLD disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.060
disease of metabolism DOID:0014667 0 0.035
inherited metabolic disorder DOID:655 0 0.035
nervous system disease DOID:863 0 0.028
musculoskeletal system disease DOID:17 0 0.022
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016
organ system cancer DOID:0050686 0 0.012