Drosophila melanogaster

72 known processes

eRF1 (Dmel_CG5605)

eukaryotic release factor 1

(Aliases: CG5605,l(3)05637,group J,l(3)neo28,l(3)77ABb,Dm0184,l(3)00103,Group J,Dmel\CG5605)

eRF1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
establishment of localization in cell GO:0051649 402 0.474
single organism intracellular transport GO:1902582 207 0.210
positive regulation of macromolecule metabolic process GO:0010604 405 0.186
cell cycle phase transition GO:0044770 140 0.170
synaptic transmission GO:0007268 288 0.168
cellular protein complex assembly GO:0043623 71 0.165
mitotic cell cycle phase transition GO:0044772 138 0.144
actin filament based process GO:0030029 220 0.136
eye development GO:0001654 323 0.131
positive regulation of gene expression GO:0010628 290 0.128
vesicle mediated transport GO:0016192 381 0.124
Worm
protein complex biogenesis GO:0070271 201 0.123
arp2 3 complex mediated actin nucleation GO:0034314 3 0.122
response to abiotic stimulus GO:0009628 341 0.120
response to starvation GO:0042594 97 0.102
organic substance transport GO:0071702 257 0.100
intracellular transport GO:0046907 228 0.099
male gamete generation GO:0048232 201 0.093
cytoplasmic transport GO:0016482 130 0.087
response to light stimulus GO:0009416 124 0.076
cell cycle checkpoint GO:0000075 95 0.069
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.064
spermatogenesis GO:0007283 200 0.061
dna integrity checkpoint GO:0031570 81 0.060
endocytosis GO:0006897 310 0.059
Worm
regulation of cell cycle phase transition GO:1901987 130 0.058
transcription from rna polymerase ii promoter GO:0006366 368 0.058
cellular protein localization GO:0034613 160 0.057
development of primary sexual characteristics GO:0045137 50 0.055
Worm
regulation of anatomical structure morphogenesis GO:0022603 242 0.053
striated muscle myosin thick filament assembly GO:0071688 3 0.053
positive regulation of transcription dna templated GO:0045893 266 0.049
cellular response to dna damage stimulus GO:0006974 223 0.048
dna damage checkpoint GO:0000077 78 0.045
death GO:0016265 284 0.044
actin cytoskeleton organization GO:0030036 206 0.044
protein modification process GO:0036211 438 0.042
establishment of organelle localization GO:0051656 122 0.042
chaeta morphogenesis GO:0008407 42 0.042
gonad development GO:0008406 50 0.041
Worm
compound eye morphogenesis GO:0001745 249 0.040
response to radiation GO:0009314 155 0.040
compound eye development GO:0048749 307 0.038
regulation of developmental growth GO:0048638 174 0.037
positive regulation of developmental process GO:0051094 143 0.035
protein localization GO:0008104 284 0.032
mitotic dna damage checkpoint GO:0044773 74 0.031
translation GO:0006412 69 0.029
cellular response to chemical stimulus GO:0070887 199 0.029
regulation of mitotic cell cycle phase transition GO:1901990 130 0.029
stem cell differentiation GO:0048863 117 0.029
small gtpase mediated signal transduction GO:0007264 88 0.029
protein complex assembly GO:0006461 200 0.028
regulation of multicellular organismal development GO:2000026 414 0.028
regulation of anatomical structure size GO:0090066 163 0.027
meiotic cytokinesis GO:0033206 33 0.026
regulation of immune system process GO:0002682 176 0.026
intracellular signal transduction GO:0035556 300 0.025
negative regulation of cellular metabolic process GO:0031324 382 0.025
phagocytosis GO:0006909 215 0.025
nuclear division GO:0000280 332 0.024
cellular protein modification process GO:0006464 438 0.023
negative regulation of cell cycle phase transition GO:1901988 103 0.023
epithelial cell development GO:0002064 274 0.022
posttranscriptional regulation of gene expression GO:0010608 145 0.022
embryo development ending in birth or egg hatching GO:0009792 152 0.022
Worm
translational initiation GO:0006413 11 0.022
actin filament organization GO:0007015 126 0.022
protein prenylation GO:0018342 3 0.022
positive regulation of multicellular organismal process GO:0051240 143 0.022
amine metabolic process GO:0009308 12 0.021
cellular macromolecule localization GO:0070727 220 0.021
mitotic dna integrity checkpoint GO:0044774 75 0.021
negative regulation of cell cycle process GO:0010948 109 0.021
positive regulation of rna metabolic process GO:0051254 271 0.020
hematopoietic progenitor cell differentiation GO:0002244 1 0.020
striated muscle cell differentiation GO:0051146 90 0.020
growth GO:0040007 359 0.020
sex differentiation GO:0007548 81 0.020
Worm
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.019
developmental programmed cell death GO:0010623 138 0.019
reproductive system development GO:0061458 74 0.019
Worm
positive regulation of nucleic acid templated transcription GO:1903508 266 0.019
response to nutrient levels GO:0031667 114 0.019
positive regulation of transport GO:0051050 92 0.018
establishment of protein localization GO:0045184 163 0.018
regulation of response to stress GO:0080134 200 0.018
axon development GO:0061564 297 0.018
regulation of phosphate metabolic process GO:0019220 210 0.018
carbohydrate metabolic process GO:0005975 82 0.018
cellular nitrogen compound catabolic process GO:0044270 165 0.018
regulation of cellular localization GO:0060341 136 0.017
regulation of mrna 3 end processing GO:0031440 7 0.017
regulation of programmed cell death GO:0043067 152 0.017
cell division GO:0051301 248 0.017
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.017
regulation of cellular protein metabolic process GO:0032268 243 0.017
cellular component assembly involved in morphogenesis GO:0010927 151 0.017
protein localization to organelle GO:0033365 82 0.017
mitotic cell cycle checkpoint GO:0007093 88 0.017
rna localization GO:0006403 115 0.017
trna aminoacylation for protein translation GO:0006418 2 0.017
negative regulation of cell cycle GO:0045786 116 0.017
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.017
regulation of cellular component biogenesis GO:0044087 201 0.016
response to oxygen levels GO:0070482 59 0.016
establishment of protein localization to organelle GO:0072594 62 0.016
negative regulation of biosynthetic process GO:0009890 277 0.016
prenylation GO:0097354 3 0.016
meiotic cell cycle GO:0051321 171 0.016
macromolecular complex assembly GO:0065003 256 0.016
immune system process GO:0002376 347 0.016
protein transport GO:0015031 155 0.015
regulation of hemocyte proliferation GO:0035206 37 0.015
cell cycle g1 s phase transition GO:0044843 31 0.014
central nervous system development GO:0007417 201 0.014
smoothened signaling pathway GO:0007224 49 0.014
regulation of molecular function GO:0065009 217 0.014
mesenchymal cell development GO:0014031 1 0.014
regulation of cell shape GO:0008360 113 0.013
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.013
negative regulation of developmental process GO:0051093 201 0.013
regulation of cytoplasmic transport GO:1903649 47 0.013
mesenchymal cell differentiation GO:0048762 1 0.013
purine ribonucleoside catabolic process GO:0046130 112 0.013
dendrite morphogenesis GO:0048813 199 0.013
cell proliferation GO:0008283 299 0.013
positive regulation of molecular function GO:0044093 136 0.013
axon guidance GO:0007411 233 0.013
cell death GO:0008219 279 0.013
positive regulation of rna biosynthetic process GO:1902680 266 0.012
regulation of cellular component size GO:0032535 98 0.012
regulation of g1 s transition of mitotic cell cycle GO:2000045 23 0.012
organelle localization GO:0051640 148 0.012
regulation of transport GO:0051049 181 0.012
developmental maturation GO:0021700 172 0.012
autophagy GO:0006914 108 0.012
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 1 0.012
regulation of localization GO:0032879 275 0.012
regulation of golgi to plasma membrane protein transport GO:0042996 6 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.012
response to other organism GO:0051707 293 0.011
positive regulation of cellular protein metabolic process GO:0032270 118 0.011
cell cell signaling involved in cell fate commitment GO:0045168 210 0.011
mitotic g2 m transition checkpoint GO:0044818 70 0.011
negative regulation of cell differentiation GO:0045596 143 0.011
positive regulation of cellular biosynthetic process GO:0031328 316 0.011
nucleocytoplasmic transport GO:0006913 72 0.011
positive regulation of biosynthetic process GO:0009891 316 0.011
brain development GO:0007420 120 0.011
secretion GO:0046903 109 0.011
regulation of mitotic cell cycle GO:0007346 190 0.011
cytoplasm organization GO:0007028 64 0.011
regulation of cell cycle GO:0051726 291 0.011
extrinsic apoptotic signaling pathway GO:0097191 1 0.011
mitotic g2 dna damage checkpoint GO:0007095 69 0.011
regulation of phosphorus metabolic process GO:0051174 210 0.011
genitalia development GO:0048806 26 0.011
positive regulation of cellular component biogenesis GO:0044089 80 0.011
regulation of cell proliferation GO:0042127 163 0.010
organelle fission GO:0048285 340 0.010
meiotic cell cycle process GO:1903046 132 0.010
asymmetric stem cell division GO:0098722 49 0.010
response to bacterium GO:0009617 198 0.010
single organism cellular localization GO:1902580 180 0.010
intracellular protein transmembrane import GO:0044743 4 0.010
negative regulation of apoptotic process GO:0043066 63 0.010
regulation of hydrolase activity GO:0051336 97 0.010

eRF1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
cardiovascular system disease DOID:1287 0 0.010
muscular disease DOID:0080000 0 0.010
musculoskeletal system disease DOID:17 0 0.010
muscle tissue disease DOID:66 0 0.010