Drosophila melanogaster

87 known processes

nos (Dmel_CG5637)

nanos

(Aliases: Dmel\CG5637,l(3)j3B6,CG5637,Dronanos,NANOS,DRONANOS,l(3)j4B6,Nos,l(3)07117,nNOS,NOS)

nos biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
germ line stem cell maintenance GO:0030718 50 0.980
negative regulation of cell communication GO:0010648 223 0.942
Mouse
dendrite development GO:0016358 204 0.927
female germ line stem cell asymmetric division GO:0048132 14 0.916
pole plasm protein localization GO:0007318 10 0.902
germline stem cell asymmetric division GO:0098728 15 0.900
dorsal appendage formation GO:0046843 47 0.764
regulation of pole plasm oskar mrna localization GO:0007317 27 0.735
nuclear division GO:0000280 332 0.690
oocyte maturation GO:0001556 3 0.602
growth GO:0040007 359 0.587
Zebrafish
organelle fission GO:0048285 340 0.562
negative regulation of developmental process GO:0051093 201 0.560
catabolic process GO:0009056 409 0.531
Mouse
purine nucleoside metabolic process GO:0042278 127 0.519
germ line stem cell division GO:0042078 25 0.518
cellular nitrogen compound catabolic process GO:0044270 165 0.483
Mouse
regulation of cell cycle GO:0051726 291 0.469
Mouse
central nervous system development GO:0007417 201 0.456
oocyte microtubule cytoskeleton polarization GO:0008103 22 0.448
regulation of multicellular organismal development GO:2000026 414 0.422
cuticle pigmentation GO:0048067 22 0.400
pole plasm assembly GO:0007315 61 0.400
posttranscriptional gene silencing by rna GO:0035194 45 0.377
actin filament organization GO:0007015 126 0.362
regulation of meiosis GO:0040020 3 0.351
Mouse
heterocycle catabolic process GO:0046700 166 0.343
Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.336
transcription from rna polymerase ii promoter GO:0006366 368 0.336
oocyte differentiation GO:0009994 145 0.321
Zebrafish
multicellular organism growth GO:0035264 46 0.310
oocyte microtubule cytoskeleton organization GO:0016325 35 0.299
protein modification process GO:0036211 438 0.299
negative regulation of cellular metabolic process GO:0031324 382 0.295
meiotic cell cycle GO:0051321 171 0.293
eggshell chorion assembly GO:0007306 66 0.291
meiotic cell cycle process GO:1903046 132 0.288
response to temperature stimulus GO:0009266 106 0.255
developmental growth GO:0048589 280 0.254
Zebrafish
establishment or maintenance of cell polarity GO:0007163 167 0.251
response to light stimulus GO:0009416 124 0.250
germ cell migration GO:0008354 43 0.248
translation GO:0006412 69 0.247
Mouse
oocyte development GO:0048599 124 0.246
Zebrafish
negative regulation of response to stimulus GO:0048585 258 0.236
Mouse
tube development GO:0035295 244 0.234
negative regulation of gene expression GO:0010629 387 0.231
regionalization GO:0003002 416 0.228
dendrite morphogenesis GO:0048813 199 0.226
response to organic cyclic compound GO:0014070 89 0.225
positive regulation of biosynthetic process GO:0009891 316 0.221
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.219
ovarian fusome organization GO:0030723 11 0.218
negative regulation of signal transduction GO:0009968 206 0.216
Mouse
organic substance catabolic process GO:1901575 308 0.208
Mouse
single organism behavior GO:0044708 391 0.205
regulation of cell differentiation GO:0045595 302 0.203
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.201
response to organic substance GO:0010033 284 0.197
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.196
cellular component assembly involved in morphogenesis GO:0010927 151 0.192
stem cell maintenance GO:0019827 67 0.189
positive regulation of translation GO:0045727 12 0.185
head development GO:0060322 135 0.181
wing disc morphogenesis GO:0007472 344 0.177
synapse assembly GO:0007416 143 0.176
synaptic growth at neuromuscular junction GO:0051124 119 0.171
meiotic nuclear division GO:0007126 151 0.168
nucleoside triphosphate metabolic process GO:0009141 120 0.167
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.166
organonitrogen compound metabolic process GO:1901564 318 0.161
oocyte axis specification GO:0007309 108 0.158
cellular response to chemical stimulus GO:0070887 199 0.154
tissue morphogenesis GO:0048729 297 0.149
digestive tract morphogenesis GO:0048546 127 0.149
regulation of oocyte development GO:0060281 27 0.149
embryo development ending in birth or egg hatching GO:0009792 152 0.148
Worm
imaginal disc derived appendage development GO:0048737 399 0.147
purine nucleoside triphosphate metabolic process GO:0009144 119 0.147
positive regulation of multicellular organism growth GO:0040018 21 0.143
stem cell differentiation GO:0048863 117 0.143
anterior posterior axis specification GO:0009948 109 0.140
regulation of catabolic process GO:0009894 170 0.138
chorion containing eggshell formation GO:0007304 105 0.136
positive regulation of developmental growth GO:0048639 62 0.135
macromolecular complex assembly GO:0065003 256 0.130
leg disc morphogenesis GO:0007478 80 0.130
eggshell formation GO:0030703 105 0.128
response to nutrient levels GO:0031667 114 0.124
positive regulation of cell communication GO:0010647 250 0.123
oocyte anterior posterior axis specification GO:0007314 72 0.123
synapse organization GO:0050808 196 0.122
cellular protein modification process GO:0006464 438 0.120
ribonucleoside catabolic process GO:0042454 112 0.120
brain development GO:0007420 120 0.114
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.111
cytoplasm organization GO:0007028 64 0.110
negative regulation of signaling GO:0023057 219 0.108
Mouse
regulation of multicellular organism growth GO:0040014 40 0.107
regulation of molecular function GO:0065009 217 0.102
purine ribonucleotide catabolic process GO:0009154 109 0.102
neurological system process GO:0050877 358 0.102
regulation of developmental growth GO:0048638 174 0.101
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.101
fusome organization GO:0045478 13 0.100
regulation of response to extracellular stimulus GO:0032104 18 0.098
regulation of translation GO:0006417 56 0.096
Mouse
microtubule organizing center organization GO:0031023 168 0.096
organophosphate metabolic process GO:0019637 195 0.096
purine ribonucleoside metabolic process GO:0046128 127 0.095
dorsal ventral pattern formation GO:0009953 133 0.095
morphogenesis of embryonic epithelium GO:0016331 94 0.093
nucleoside triphosphate catabolic process GO:0009143 108 0.092
regulation of meiotic cell cycle GO:0051445 9 0.090
Mouse
neuromuscular junction development GO:0007528 149 0.090
ribonucleoside triphosphate metabolic process GO:0009199 119 0.090
imaginal disc derived appendage morphogenesis GO:0035114 395 0.090
negative regulation of cellular biosynthetic process GO:0031327 277 0.090
meiotic chromosome segregation GO:0045132 59 0.090
cellular macromolecule catabolic process GO:0044265 136 0.089
Mouse
positive regulation of cellular biosynthetic process GO:0031328 316 0.089
maintenance of gastrointestinal epithelium GO:0030277 3 0.086
oocyte nucleus localization involved in oocyte dorsal ventral axis specification GO:0051663 12 0.084
axis specification GO:0009798 167 0.084
pole cell development GO:0007277 26 0.083
positive regulation of lipid biosynthetic process GO:0046889 3 0.082
oocyte construction GO:0007308 112 0.081
developmental maturation GO:0021700 172 0.079
response to abiotic stimulus GO:0009628 341 0.079
ribonucleoprotein complex subunit organization GO:0071826 28 0.079
regulation of cellular protein metabolic process GO:0032268 243 0.079
Mouse
locomotor rhythm GO:0045475 56 0.078
spermatogenesis GO:0007283 200 0.078
cardiac cell fate commitment GO:0060911 17 0.078
negative regulation of cell cycle GO:0045786 116 0.076
Mouse
defense response to bacterium GO:0042742 178 0.075
positive regulation of transcription dna templated GO:0045893 266 0.073
cystoblast division GO:0007282 10 0.072
ribonucleoside triphosphate catabolic process GO:0009203 108 0.071
positive regulation of rna metabolic process GO:0051254 271 0.071
germarium derived egg chamber formation GO:0007293 101 0.069
negative regulation of phosphatase activity GO:0010923 3 0.069
aromatic compound catabolic process GO:0019439 166 0.068
Mouse
stem cell division GO:0017145 69 0.068
regulation of phosphorus metabolic process GO:0051174 210 0.067
ribose phosphate metabolic process GO:0019693 145 0.067
nucleotide catabolic process GO:0009166 109 0.067
digestive tract development GO:0048565 149 0.066
purine nucleotide metabolic process GO:0006163 146 0.065
gene silencing GO:0016458 138 0.064
female meiosis chromosome segregation GO:0016321 33 0.063
purine nucleotide catabolic process GO:0006195 109 0.061
dna metabolic process GO:0006259 227 0.060
tripartite regional subdivision GO:0007351 103 0.060
anterior posterior axis specification embryo GO:0008595 103 0.059
pole cell formation GO:0007279 19 0.058
single organism catabolic process GO:0044712 228 0.058
positive regulation of gene expression GO:0010628 290 0.058
negative regulation of erbb signaling pathway GO:1901185 29 0.057
regulation of cell cycle process GO:0010564 181 0.057
Mouse
chemotaxis GO:0006935 249 0.057
nucleobase containing small molecule metabolic process GO:0055086 174 0.057
embryonic development via the syncytial blastoderm GO:0001700 148 0.057
transmembrane transport GO:0055085 139 0.056
purine containing compound catabolic process GO:0072523 112 0.054
pole plasm mrna localization GO:0019094 49 0.054
positive regulation of catabolic process GO:0009896 105 0.053
regulation of transposition GO:0010528 13 0.053
segmentation GO:0035282 207 0.052
regulation of cellular catabolic process GO:0031329 157 0.052
germarium derived female germ line cyst encapsulation GO:0030708 8 0.052
dorsal ventral axis specification GO:0009950 66 0.051
carbohydrate derivative catabolic process GO:1901136 118 0.051
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.049
spindle organization GO:0007051 253 0.049
small molecule metabolic process GO:0044281 305 0.049
posttranscriptional gene silencing GO:0016441 46 0.049
response to decreased oxygen levels GO:0036293 58 0.047
response to wounding GO:0009611 94 0.046
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.045
renal system development GO:0072001 72 0.045
embryonic axis specification GO:0000578 107 0.045
post embryonic appendage morphogenesis GO:0035120 385 0.044
dormancy process GO:0022611 2 0.044
response to extracellular stimulus GO:0009991 116 0.044
regulation of dna metabolic process GO:0051052 34 0.043
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.043
negative regulation of autophagy GO:0010507 16 0.042
regulation of defense response GO:0031347 102 0.042
purine nucleoside triphosphate catabolic process GO:0009146 108 0.041
negative regulation of macroautophagy GO:0016242 6 0.041
appendage morphogenesis GO:0035107 397 0.041
purine containing compound metabolic process GO:0072521 155 0.040
endocytosis GO:0006897 310 0.039
positive regulation of signaling GO:0023056 243 0.039
negative regulation of defense response GO:0031348 35 0.039
cell death GO:0008219 279 0.038
response to endogenous stimulus GO:0009719 119 0.038
anterior posterior pattern specification GO:0009952 136 0.038
digestive system development GO:0055123 149 0.038
negative regulation of growth GO:0045926 84 0.037
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.036
ribonucleoside metabolic process GO:0009119 127 0.035
regulation of cell development GO:0060284 215 0.035
purine nucleoside catabolic process GO:0006152 112 0.035
establishment of localization in cell GO:0051649 402 0.035
stem cell development GO:0048864 79 0.034
nucleoside catabolic process GO:0009164 112 0.033
response to bacterium GO:0009617 198 0.033
organic cyclic compound catabolic process GO:1901361 168 0.032
Mouse
ribonucleotide metabolic process GO:0009259 145 0.032
regulation of pathway restricted smad protein phosphorylation GO:0060393 1 0.032
positive regulation of cellular catabolic process GO:0031331 95 0.032
regulation of phosphatase activity GO:0010921 3 0.031
regulation of immune system process GO:0002682 176 0.031
atp metabolic process GO:0046034 49 0.031
dna replication GO:0006260 48 0.031
regulation of cell division GO:0051302 72 0.031
Mouse
localization of cell GO:0051674 257 0.031
nucleoside phosphate metabolic process GO:0006753 162 0.030
regulation of synapse organization GO:0050807 110 0.030
sex differentiation GO:0007548 81 0.030
purine ribonucleotide metabolic process GO:0009150 145 0.030
organophosphate catabolic process GO:0046434 112 0.030
chromosome segregation GO:0007059 157 0.030
nucleotide metabolic process GO:0009117 161 0.030
carbohydrate derivative metabolic process GO:1901135 217 0.030
response to alcohol GO:0097305 95 0.029
nucleoside monophosphate metabolic process GO:0009123 52 0.029
cellular response to organic cyclic compound GO:0071407 32 0.029
nucleoside phosphate catabolic process GO:1901292 110 0.028
macromolecule catabolic process GO:0009057 161 0.028
Mouse
positive regulation of rna biosynthetic process GO:1902680 266 0.028
negative regulation of response to nutrient levels GO:0032108 6 0.028
cellularization GO:0007349 90 0.028
purine ribonucleoside catabolic process GO:0046130 112 0.028
regulation of gtpase activity GO:0043087 44 0.028
positive regulation of hydrolase activity GO:0051345 78 0.027
male gamete generation GO:0048232 201 0.027
regulation of phosphate metabolic process GO:0019220 210 0.027
ovarian follicle cell development GO:0030707 248 0.027
epithelial cell migration GO:0010631 148 0.027
embryonic morphogenesis GO:0048598 206 0.027
death GO:0016265 284 0.027
negative regulation of response to extracellular stimulus GO:0032105 6 0.027
positive regulation of pathway restricted smad protein phosphorylation GO:0010862 1 0.027
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.026
female meiotic division GO:0007143 70 0.026
regulation of hydrolase activity GO:0051336 97 0.026
ribonucleotide catabolic process GO:0009261 109 0.026
apoptotic process GO:0006915 159 0.026
regulation of localization GO:0032879 275 0.026
regulation of ras protein signal transduction GO:0046578 93 0.025
enzyme linked receptor protein signaling pathway GO:0007167 179 0.025
intracellular signal transduction GO:0035556 300 0.024
regulation of apoptotic process GO:0042981 130 0.024
oocyte localization involved in germarium derived egg chamber formation GO:0030720 12 0.024
positive regulation of signal transduction GO:0009967 223 0.023
carboxylic acid metabolic process GO:0019752 92 0.023
phagocytosis GO:0006909 215 0.023
intracellular receptor signaling pathway GO:0030522 19 0.023
regulation of anatomical structure size GO:0090066 163 0.023
tube morphogenesis GO:0035239 191 0.023
glycosyl compound catabolic process GO:1901658 112 0.023
glycosyl compound metabolic process GO:1901657 127 0.023
cellular catabolic process GO:0044248 372 0.023
Mouse
taxis GO:0042330 304 0.023
regulation of actin polymerization or depolymerization GO:0008064 27 0.022
phosphorylation GO:0016310 294 0.022
developmental programmed cell death GO:0010623 138 0.022
border follicle cell migration GO:0007298 113 0.021
meiotic cell cycle phase transition GO:0044771 4 0.021
gene silencing by rna GO:0031047 57 0.021
ameboidal type cell migration GO:0001667 151 0.021
determination of adult lifespan GO:0008340 137 0.020
negative regulation of cellular response to oxidative stress GO:1900408 1 0.020
body morphogenesis GO:0010171 2 0.020
regulation of nucleoside metabolic process GO:0009118 50 0.020
regulation of embryonic pattern specification GO:1902875 27 0.020
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.020
cell division GO:0051301 248 0.020
Mouse
cell motility GO:0048870 251 0.019
actin filament based process GO:0030029 220 0.019
negative regulation of transcription dna templated GO:0045892 237 0.019
cognition GO:0050890 141 0.019
negative regulation of meiotic cell cycle GO:0051447 2 0.019
Mouse
molting cycle process GO:0022404 29 0.018
regulation of autophagy GO:0010506 62 0.018
negative regulation of rna biosynthetic process GO:1902679 240 0.018
forebrain development GO:0030900 2 0.018
regulation of nervous system development GO:0051960 248 0.018
positive regulation of growth GO:0045927 75 0.018
organonitrogen compound catabolic process GO:1901565 128 0.018
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.018
hematopoietic progenitor cell differentiation GO:0002244 1 0.017
nucleobase containing compound catabolic process GO:0034655 165 0.017
Mouse
small gtpase mediated signal transduction GO:0007264 88 0.017
cellular amide metabolic process GO:0043603 80 0.017
regulation of nuclear division GO:0051783 58 0.017
Mouse
female germ line cyst formation GO:0048135 42 0.017
regulation of viral genome replication GO:0045069 4 0.016
base excision repair GO:0006284 2 0.016
convergent extension GO:0060026 2 0.016
regulation of catalytic activity GO:0050790 185 0.015
hindgut morphogenesis GO:0007442 58 0.015
actin filament bundle assembly GO:0051017 26 0.015
mitotic spindle organization GO:0007052 220 0.015
positive regulation of multicellular organismal process GO:0051240 143 0.015
positive regulation of macromolecule metabolic process GO:0010604 405 0.015
nephron development GO:0072006 3 0.015
blastoderm segmentation GO:0007350 159 0.015
molting cycle chitin based cuticle GO:0007591 56 0.015
epithelial cell migration open tracheal system GO:0007427 32 0.015
guanosine containing compound catabolic process GO:1901069 74 0.015
regulation of cuticle pigmentation GO:0048079 16 0.015
negative regulation of protein metabolic process GO:0051248 85 0.015
negative regulation of mitotic cell cycle GO:0045930 109 0.015
negative regulation of cellular protein metabolic process GO:0032269 85 0.015
oxidation reduction process GO:0055114 123 0.015
dorsal closure GO:0007391 79 0.014
response to radiation GO:0009314 155 0.014
protein complex biogenesis GO:0070271 201 0.014
regulation of mrna metabolic process GO:1903311 72 0.014
positive regulation of phosphorus metabolic process GO:0010562 139 0.014
regulation of actin filament polymerization GO:0030833 25 0.014
regulation of protein catabolic process GO:0042176 55 0.014
protein depolymerization GO:0051261 31 0.014
negative regulation of synaptic growth at neuromuscular junction GO:0045886 39 0.014
negative regulation of cellular component organization GO:0051129 108 0.014
Mouse
histolysis GO:0007559 102 0.014
bmp signaling pathway GO:0030509 27 0.014
regulation of cellular component biogenesis GO:0044087 201 0.013
imaginal disc derived leg morphogenesis GO:0007480 80 0.013
membrane depolarization GO:0051899 4 0.013
rna splicing GO:0008380 83 0.013
larval behavior GO:0030537 42 0.013
meiosis i GO:0007127 59 0.013
protein phosphorylation GO:0006468 169 0.013
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.013
regulation of synapse assembly GO:0051963 94 0.013
positive regulation of cell cycle GO:0045787 43 0.013
response to oxygen containing compound GO:1901700 200 0.013
regulation of purine nucleotide catabolic process GO:0033121 48 0.013
dorsal closure spreading of leading edge cells GO:0007395 4 0.013
exocrine system development GO:0035272 162 0.013
ribonucleoprotein complex biogenesis GO:0022613 31 0.013
mitotic nuclear division GO:0007067 213 0.012
mitotic chromosome condensation GO:0007076 22 0.012
lipid storage GO:0019915 38 0.012
embryonic pattern specification GO:0009880 174 0.012
maintenance of location GO:0051235 73 0.012
compound eye development GO:0048749 307 0.012
dorsal vessel heart proper cell fate commitment GO:0035053 2 0.012
regulation of hemocyte proliferation GO:0035206 37 0.012
regulation of phosphoprotein phosphatase activity GO:0043666 3 0.012
gtp metabolic process GO:0046039 72 0.012
cellular response to ecdysone GO:0071390 17 0.012
positive regulation of cell size GO:0045793 21 0.012
programmed cell death GO:0012501 257 0.012
positive regulation of chromosome segregation GO:0051984 10 0.012
cellular response to organic substance GO:0071310 132 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.012
epithelial tube morphogenesis GO:0060562 88 0.012
antimicrobial humoral response GO:0019730 99 0.012
maternal determination of anterior posterior axis embryo GO:0008358 74 0.011
negative regulation of epithelial cell migration GO:0010633 1 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 38 0.011
regulation of embryonic development GO:0045995 68 0.011
negative regulation of notch signaling pathway GO:0045746 41 0.011
negative regulation of nucleic acid templated transcription GO:1903507 240 0.011
neuroblast development GO:0014019 13 0.011
negative regulation of phosphorus metabolic process GO:0010563 45 0.011
regulation of protein metabolic process GO:0051246 256 0.011
Mouse
cation transport GO:0006812 110 0.011
female germ line cyst encapsulation GO:0048139 8 0.011
regulation of growth GO:0040008 233 0.011
mushroom body development GO:0016319 70 0.011
response to toxic substance GO:0009636 22 0.011
tissue migration GO:0090130 155 0.010
ovarian follicle cell stalk formation GO:0030713 17 0.010
morphogenesis of an epithelium GO:0002009 276 0.010
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.010
mrna processing GO:0006397 104 0.010
regulation of ras gtpase activity GO:0032318 38 0.010
regulation of organelle organization GO:0033043 196 0.010
Mouse
positive regulation of nucleoside metabolic process GO:0045979 47 0.010
stress granule disassembly GO:0035617 1 0.010
tissue death GO:0016271 102 0.010

nos disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
muscular disease DOID:0080000 0 0.028
disease of anatomical entity DOID:7 0 0.028
musculoskeletal system disease DOID:17 0 0.028
muscle tissue disease DOID:66 0 0.028
cardiovascular system disease DOID:1287 0 0.021