Drosophila melanogaster

194 known processes

Pp1-87B (Dmel_CG5650)

Protein phosphatase 1 at 87B

(Aliases: Su(var)3-6,PP1alpha87B,Pp1alpha-87B,l(3)j6E7,l(3)ck19,PP1 87B,su-var(3)6,PP1 beta87b,Su(Var)3-6,CG5650,l(3)87Bg,Pp1,PP1-87B,Pp-1alpha,Suvar(3)6,PP187B,PP1c 87B,PP1,PP1c,PP-1alpha,ck19,Pp1-87Bb,87B,Su-var(3)6,Dmel\CG5650,PP1A87B,DmPp1-87B,Su(var)(3)6,PP1alpha[[2]],Ppl-87B)

Pp1-87B biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cell cycle phase transition GO:1901987 130 0.998
Yeast
chromosome segregation GO:0007059 157 0.995
regulation of protein dephosphorylation GO:0035304 5 0.994
Yeast
negative regulation of cell cycle GO:0045786 116 0.993
Yeast
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.989
Yeast
chromatin silencing GO:0006342 76 0.979
Yeast
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.976
Yeast
mitotic spindle organization GO:0007052 220 0.976
gene silencing GO:0016458 138 0.974
Yeast
negative regulation of cell cycle phase transition GO:1901988 103 0.973
Yeast
negative regulation of mitotic cell cycle GO:0045930 109 0.963
Yeast
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.961
Yeast
negative regulation of cellular biosynthetic process GO:0031327 277 0.959
Yeast
regulation of mitotic cell cycle phase transition GO:1901990 130 0.959
Yeast
meiotic nuclear division GO:0007126 151 0.955
Yeast Worm
negative regulation of gene expression GO:0010629 387 0.951
Yeast
protein modification process GO:0036211 438 0.943
organelle assembly GO:0070925 198 0.939
negative regulation of cellular metabolic process GO:0031324 382 0.934
Yeast
embryo development ending in birth or egg hatching GO:0009792 152 0.931
Worm
negative regulation of chromosome segregation GO:0051985 14 0.916
Yeast
cell cycle phase transition GO:0044770 140 0.896
Yeast
modification dependent macromolecule catabolic process GO:0043632 79 0.890
Yeast
spindle assembly GO:0051225 80 0.885
regulation of protein modification process GO:0031399 112 0.883
Yeast
mitotic cell cycle checkpoint GO:0007093 88 0.881
Yeast
spindle organization GO:0007051 253 0.878
regulation of cell cycle process GO:0010564 181 0.875
Yeast
negative regulation of rna metabolic process GO:0051253 251 0.871
Yeast
reproductive system development GO:0061458 74 0.869
sister chromatid segregation GO:0000819 92 0.861
mitotic sister chromatid segregation GO:0000070 87 0.846
mitotic cell cycle phase transition GO:0044772 138 0.834
Yeast
dna damage checkpoint GO:0000077 78 0.831
Yeast
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.831
Yeast
negative regulation of biosynthetic process GO:0009890 277 0.831
Yeast
covalent chromatin modification GO:0016569 106 0.822
Yeast
negative regulation of transcription dna templated GO:0045892 237 0.817
Yeast
negative regulation of gene expression epigenetic GO:0045814 77 0.811
Yeast
regulation of localization GO:0032879 275 0.785
Mouse
chromatin modification GO:0016568 147 0.777
Yeast
protein dephosphorylation GO:0006470 27 0.774
nuclear division GO:0000280 332 0.772
immune response GO:0006955 246 0.768
Fly
chromosome condensation GO:0030261 41 0.723
cell proliferation GO:0008283 299 0.713
spindle assembly involved in mitosis GO:0090307 50 0.712
cell division GO:0051301 248 0.695
Yeast Worm
circadian rhythm GO:0007623 105 0.692
Human Mouse
vesicle mediated transport GO:0016192 381 0.672
rhythmic process GO:0048511 106 0.670
Human Mouse
regulation of mitotic sister chromatid segregation GO:0033047 28 0.657
Yeast
histone modification GO:0016570 106 0.655
Yeast
negative regulation of nucleic acid templated transcription GO:1903507 240 0.648
Yeast
multi multicellular organism process GO:0044706 123 0.638
Worm Fly
regulation of chromosome organization GO:0033044 64 0.619
Yeast
rrna processing GO:0006364 3 0.588
Yeast
sex differentiation GO:0007548 81 0.549
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.543
Yeast
regulation of organelle organization GO:0033043 196 0.540
Yeast
reproductive structure development GO:0048608 74 0.530
response to abiotic stimulus GO:0009628 341 0.525
positive regulation of immune response GO:0050778 63 0.518
Fly
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.510
Yeast
negative regulation of cell cycle process GO:0010948 109 0.504
Yeast
negative regulation of chromosome organization GO:2001251 19 0.482
Yeast
cellular macromolecule localization GO:0070727 220 0.455
Yeast
regulation of cell cycle GO:0051726 291 0.453
Yeast
axon guidance GO:0007411 233 0.444
chemosensory behavior GO:0007635 106 0.441
defense response to other organism GO:0098542 225 0.436
Fly
chromosome organization GO:0051276 360 0.428
regulation of cellular protein catabolic process GO:1903362 44 0.424
Yeast
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 8 0.411
meiotic cell cycle GO:0051321 171 0.410
Yeast Worm
regulation of cellular localization GO:0060341 136 0.390
Mouse
negative regulation of cellular component organization GO:0051129 108 0.368
Yeast
spindle elongation GO:0051231 83 0.367
g2 dna damage checkpoint GO:0031572 69 0.362
epidermis development GO:0008544 65 0.352
regulation of cellular protein metabolic process GO:0032268 243 0.348
Yeast
negative regulation of rna biosynthetic process GO:1902679 240 0.345
Yeast
endocytosis GO:0006897 310 0.337
cellular catabolic process GO:0044248 372 0.336
Yeast
mitotic spindle elongation GO:0000022 81 0.335
organelle fission GO:0048285 340 0.326
centrosome cycle GO:0007098 137 0.318
cellular protein localization GO:0034613 160 0.306
Yeast
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.302
single organism behavior GO:0044708 391 0.297
nuclear transport GO:0051169 72 0.291
Mouse
response to radiation GO:0009314 155 0.283
negative regulation of organelle organization GO:0010639 56 0.276
Yeast
regulation of cell division GO:0051302 72 0.275
Yeast
development of primary sexual characteristics GO:0045137 50 0.269
dna replication GO:0006260 48 0.258
Yeast
negative regulation of phosphate metabolic process GO:0045936 45 0.255
phosphorylation GO:0016310 294 0.252
dna metabolic process GO:0006259 227 0.245
regulation of immune response GO:0050776 118 0.238
Fly
cell cycle checkpoint GO:0000075 95 0.235
Yeast
immune system process GO:0002376 347 0.231
Fly
cytoplasmic transport GO:0016482 130 0.228
Mouse
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.224
Yeast
response to light stimulus GO:0009416 124 0.223
catabolic process GO:0009056 409 0.222
Yeast
gonad development GO:0008406 50 0.222
mitotic sister chromatid separation GO:0051306 30 0.221
Yeast
proteolysis GO:0006508 192 0.215
Yeast
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.211
Yeast
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 16 0.208
Yeast
dna packaging GO:0006323 91 0.206
dephosphorylation GO:0016311 51 0.205
retina development in camera type eye GO:0060041 4 0.198
regulation of intracellular transport GO:0032386 64 0.196
Mouse
protein transport GO:0015031 155 0.194
mitotic g2 m transition checkpoint GO:0044818 70 0.193
regulation of gene expression epigenetic GO:0040029 128 0.190
Yeast
meiotic chromosome segregation GO:0045132 59 0.183
Worm
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 30 0.183
Yeast
regulation of phosphorylation GO:0042325 147 0.172
posttranscriptional gene silencing GO:0016441 46 0.171
learning or memory GO:0007611 141 0.165
sensory organ morphogenesis GO:0090596 260 0.163
ribonucleoside monophosphate catabolic process GO:0009158 39 0.162
cellular protein catabolic process GO:0044257 83 0.160
Yeast
larval development GO:0002164 104 0.160
rna interference GO:0016246 27 0.160
regulation of chromosome segregation GO:0051983 32 0.160
Yeast
establishment of organelle localization GO:0051656 122 0.156
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 17 0.153
Yeast
cellular protein modification process GO:0006464 438 0.152
eye development GO:0001654 323 0.148
genitalia development GO:0048806 26 0.145
regulation of proteasomal protein catabolic process GO:0061136 39 0.143
Yeast
chromosome localization GO:0050000 20 0.141
regulation of meiosis GO:0040020 3 0.137
rna processing GO:0006396 147 0.135
Yeast
negative regulation of cell division GO:0051782 17 0.134
Yeast
regulation of growth GO:0040008 233 0.134
protein complex assembly GO:0006461 200 0.133
cellular macromolecule catabolic process GO:0044265 136 0.130
Yeast
regulation of transport GO:0051049 181 0.127
Mouse
dna integrity checkpoint GO:0031570 81 0.125
Yeast
adult behavior GO:0030534 137 0.122
negative regulation of phosphorus metabolic process GO:0010563 45 0.121
regulation of protein metabolic process GO:0051246 256 0.121
Yeast
oxoacid metabolic process GO:0043436 103 0.116
regulation of chromatin silencing GO:0031935 36 0.114
epithelial cell differentiation GO:0030855 322 0.114
axonogenesis GO:0007409 290 0.113
protein maturation GO:0051604 71 0.109
Yeast
protein localization GO:0008104 284 0.105
Yeast
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.104
Yeast
single organism biosynthetic process GO:0044711 206 0.102
metaphase anaphase transition of mitotic cell cycle GO:0007091 28 0.099
Yeast
regulation of proteolysis GO:0030162 87 0.098
Yeast
mitotic spindle checkpoint GO:0071174 11 0.097
Yeast
cellular response to dna damage stimulus GO:0006974 223 0.094
Yeast
dna conformation change GO:0071103 105 0.093
epithelial cell development GO:0002064 274 0.092
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.092
Yeast
mitotic dna integrity checkpoint GO:0044774 75 0.090
regulation of phosphorus metabolic process GO:0051174 210 0.089
ribonucleoprotein complex biogenesis GO:0022613 31 0.089
Yeast
mitotic nuclear division GO:0007067 213 0.085
chromatin organization GO:0006325 207 0.084
Yeast
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.083
Yeast
positive regulation of defense response GO:0031349 59 0.082
Fly
nucleoside triphosphate metabolic process GO:0009141 120 0.080
regulation of immune system process GO:0002682 176 0.075
Fly
negative regulation of protein modification process GO:0031400 29 0.072
eye morphogenesis GO:0048592 260 0.072
regulation of circadian rhythm GO:0042752 49 0.070
Human Mouse
cell junction assembly GO:0034329 42 0.070
protein localization to organelle GO:0033365 82 0.068
Yeast
single organism cellular localization GO:1902580 180 0.067
cognition GO:0050890 141 0.067
macromolecular complex assembly GO:0065003 256 0.067
cell motility GO:0048870 251 0.067
regulation of phosphate metabolic process GO:0019220 210 0.066
centrosome organization GO:0051297 163 0.061
cilium organization GO:0044782 41 0.060
olfactory learning GO:0008355 56 0.059
posttranscriptional gene silencing by rna GO:0035194 45 0.059
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.058
regulation of apoptotic process GO:0042981 130 0.057
mitotic dna damage checkpoint GO:0044773 74 0.057
organic substance transport GO:0071702 257 0.056
negative regulation of protein metabolic process GO:0051248 85 0.055
Yeast
innate immune response GO:0045087 144 0.054
Fly
sensory perception of sound GO:0007605 56 0.052
protein phosphorylation GO:0006468 169 0.052
lipid localization GO:0010876 54 0.052
negative regulation of cellular protein metabolic process GO:0032269 85 0.051
Yeast
regulation of molecular function GO:0065009 217 0.051
olfactory behavior GO:0042048 97 0.048
intracellular transport GO:0046907 228 0.048
Mouse
camera type eye development GO:0043010 4 0.048
multicellular organismal reproductive behavior GO:0033057 110 0.046
Worm
centriole replication GO:0007099 24 0.045
ubiquitin dependent protein catabolic process GO:0006511 78 0.044
Yeast
epidermal cell differentiation GO:0009913 51 0.043
response to bacterium GO:0009617 198 0.043
Fly
single organism catabolic process GO:0044712 228 0.042
Yeast
positive regulation of phosphate metabolic process GO:0045937 139 0.042
localization of cell GO:0051674 257 0.042
negative regulation of sister chromatid segregation GO:0033046 13 0.042
Yeast
brain development GO:0007420 120 0.041
aging GO:0007568 143 0.041
protein complex biogenesis GO:0070271 201 0.041
nucleocytoplasmic transport GO:0006913 72 0.040
Mouse
phagocytosis GO:0006909 215 0.039
defense response to bacterium GO:0042742 178 0.039
Fly
dna dependent dna replication GO:0006261 17 0.038
Yeast
negative regulation of protein catabolic process GO:0042177 17 0.038
Yeast
regulation of phosphatase activity GO:0010921 3 0.037
small molecule metabolic process GO:0044281 305 0.037
regulation of protein catabolic process GO:0042176 55 0.037
Yeast
regulation of mitosis GO:0007088 56 0.037
Yeast
stem cell development GO:0048864 79 0.036
reproductive behavior GO:0019098 122 0.036
Worm
negative regulation of mitotic sister chromatid segregation GO:0033048 13 0.036
Yeast
apoptotic process GO:0006915 159 0.036
positive regulation of cell cycle GO:0045787 43 0.034
regulation of protein localization GO:0032880 76 0.034
regulation of catabolic process GO:0009894 170 0.033
Yeast
locomotory behavior GO:0007626 176 0.032
negative regulation of cell communication GO:0010648 223 0.032
centriole assembly GO:0098534 24 0.031
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.031
Yeast
atp catabolic process GO:0006200 38 0.031
regulation of hemocyte proliferation GO:0035206 37 0.031
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.030
male gamete generation GO:0048232 201 0.030
regulation of multicellular organism growth GO:0040014 40 0.029
histone ubiquitination GO:0016574 4 0.029
modification dependent protein catabolic process GO:0019941 78 0.029
Yeast
positive regulation of cell communication GO:0010647 250 0.028
organic acid metabolic process GO:0006082 103 0.028
protein modification by small protein removal GO:0070646 28 0.028
atp metabolic process GO:0046034 49 0.027
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.027
regulation of chromatin organization GO:1902275 32 0.027
regulation of mitotic cell cycle GO:0007346 190 0.027
Yeast
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 11 0.027
receptor mediated endocytosis GO:0006898 21 0.027
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.026
developmental maturation GO:0021700 172 0.026
body morphogenesis GO:0010171 2 0.026
regulation of catalytic activity GO:0050790 185 0.025
mating GO:0007618 120 0.025
Fly
mitotic g2 dna damage checkpoint GO:0007095 69 0.025
regulation of programmed cell death GO:0043067 152 0.025
negative regulation of catalytic activity GO:0043086 42 0.025
wound healing GO:0042060 75 0.025
asymmetric stem cell division GO:0098722 49 0.025
positive regulation of apoptotic signaling pathway GO:2001235 4 0.025
nitrogen compound transport GO:0071705 85 0.025
regulation of meiotic cell cycle GO:0051445 9 0.025
regulation of intracellular signal transduction GO:1902531 236 0.024
molting cycle GO:0042303 56 0.024
Worm
central nervous system development GO:0007417 201 0.024
neural precursor cell proliferation GO:0061351 75 0.024
chemotaxis GO:0006935 249 0.024
regulation of cell proliferation GO:0042127 163 0.023
regulation of mitotic sister chromatid separation GO:0010965 28 0.023
Yeast
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.023
Yeast
axon development GO:0061564 297 0.023
positive regulation of biosynthetic process GO:0009891 316 0.023
response to oxygen containing compound GO:1901700 200 0.023
negative regulation of mitotic metaphase anaphase transition GO:0045841 13 0.023
Yeast
regulation of cytoplasmic transport GO:1903649 47 0.022
Mouse
protein catabolic process GO:0030163 101 0.022
Yeast
mitotic spindle assembly checkpoint GO:0007094 11 0.022
Yeast
stem cell differentiation GO:0048863 117 0.021
stem cell proliferation GO:0072089 88 0.021
signal release GO:0023061 49 0.021
purine nucleoside monophosphate catabolic process GO:0009128 38 0.021
organelle localization GO:0051640 148 0.021
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.021
neuron projection guidance GO:0097485 241 0.021
cell death GO:0008219 279 0.020
response to heat GO:0009408 63 0.020
Yeast
pigmentation GO:0043473 75 0.019
regulation of protein processing GO:0070613 32 0.019
Yeast
purine nucleoside monophosphate metabolic process GO:0009126 50 0.019
lipid storage GO:0019915 38 0.019
organic substance catabolic process GO:1901575 308 0.019
Yeast
protein processing GO:0016485 68 0.019
Yeast
negative regulation of phosphorylation GO:0042326 35 0.019
positive regulation of cellular protein metabolic process GO:0032270 118 0.019
Yeast
positive regulation of signaling GO:0023056 243 0.018
regulation of response to stress GO:0080134 200 0.018
Fly
negative regulation of protein complex disassembly GO:0043242 23 0.018
mitotic cytokinesis GO:0000281 50 0.018
transcription from rna polymerase ii promoter GO:0006366 368 0.018
Yeast
positive regulation of macromolecule metabolic process GO:0010604 405 0.017
Yeast
compound eye morphogenesis GO:0001745 249 0.017
digestive system development GO:0055123 149 0.017
ribonucleotide catabolic process GO:0009261 109 0.017
response to ionizing radiation GO:0010212 32 0.017
positive regulation of organelle organization GO:0010638 65 0.016
chromatin mediated maintenance of transcription GO:0048096 7 0.016
gene silencing by rna GO:0031047 57 0.016
asymmetric neuroblast division GO:0055059 33 0.016
carbohydrate derivative metabolic process GO:1901135 217 0.016
macromolecule catabolic process GO:0009057 161 0.016
Yeast
nuclear dna replication GO:0033260 1 0.016
multicellular organism growth GO:0035264 46 0.016
membrane budding GO:0006900 4 0.016
regulation of cellular catabolic process GO:0031329 157 0.016
Yeast
regulation of gene silencing GO:0060968 63 0.015
regulation of cellular component biogenesis GO:0044087 201 0.015
cation transmembrane transport GO:0098655 88 0.015
regulation of nuclear division GO:0051783 58 0.015
Yeast
response to organic substance GO:0010033 284 0.015
cytoskeleton dependent cytokinesis GO:0061640 81 0.015
skin development GO:0043588 65 0.015
negative regulation of protein processing GO:0010955 31 0.015
Yeast
proteasomal protein catabolic process GO:0010498 59 0.014
Yeast
positive regulation of nucleic acid templated transcription GO:1903508 266 0.014
macromolecule methylation GO:0043414 45 0.014
histone h4 k20 methylation GO:0034770 4 0.014
purine ribonucleoside monophosphate catabolic process GO:0009169 38 0.014
intracellular signal transduction GO:0035556 300 0.013
ribonucleoside monophosphate metabolic process GO:0009161 51 0.013
digestive tract development GO:0048565 149 0.013
mitotic chromosome condensation GO:0007076 22 0.013
columnar cuboidal epithelial cell development GO:0002066 249 0.013
cell migration GO:0016477 238 0.013
organonitrogen compound metabolic process GO:1901564 318 0.013
positive regulation of cell cycle process GO:0090068 28 0.013
regulation of microtubule cytoskeleton organization GO:0070507 41 0.013
maintenance of protein location GO:0045185 28 0.013
histone h2a ubiquitination GO:0033522 2 0.013
telomere capping GO:0016233 11 0.013
protein modification by small protein conjugation GO:0032446 79 0.013
developmental growth GO:0048589 280 0.013
nucleoside monophosphate metabolic process GO:0009123 52 0.012
positive regulation of developmental growth GO:0048639 62 0.012
negative regulation of signaling GO:0023057 219 0.012
actin filament based movement GO:0030048 26 0.012
histone h3 k9 modification GO:0061647 12 0.012
death GO:0016265 284 0.012
purine containing compound metabolic process GO:0072521 155 0.012
positive regulation of transcription dna templated GO:0045893 266 0.012
nucleoside monophosphate catabolic process GO:0009125 39 0.012
cellular component disassembly GO:0022411 46 0.012
response to external biotic stimulus GO:0043207 293 0.012
Fly
protein deubiquitination GO:0016579 17 0.011
lipid biosynthetic process GO:0008610 46 0.011
purine nucleoside metabolic process GO:0042278 127 0.011
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.011
regulation of sister chromatid segregation GO:0033045 28 0.011
Yeast
regulation of dna metabolic process GO:0051052 34 0.011
embryonic organ development GO:0048568 50 0.011
determination of adult lifespan GO:0008340 137 0.011
positive regulation of programmed cell death GO:0043068 62 0.011
gliogenesis GO:0042063 80 0.011
regulation of developmental growth GO:0048638 174 0.011
establishment of localization in cell GO:0051649 402 0.011
regulation of heterochromatin assembly GO:0031445 8 0.011
germ line stem cell maintenance GO:0030718 50 0.011
hematopoietic or lymphoid organ development GO:0048534 57 0.010
negative regulation of cellular catabolic process GO:0031330 34 0.010
Yeast
camera type eye morphogenesis GO:0048593 2 0.010
energy derivation by oxidation of organic compounds GO:0015980 32 0.010
Yeast
negative regulation of proteolysis GO:0045861 31 0.010
Yeast
regulation of viral genome replication GO:0045069 4 0.010

Pp1-87B disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.119
nervous system disease DOID:863 0 0.119
disease of cellular proliferation DOID:14566 0 0.075
cancer DOID:162 0 0.029
organ system cancer DOID:0050686 0 0.029