Drosophila melanogaster

25 known processes

RhoBTB (Dmel_CG5701)

CG5701 gene product from transcript CG5701-RA

(Aliases: RhoGTPase,RhoX,CG5701,Dmel\CG5701)

RhoBTB biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
encapsulation of foreign target GO:0035010 38 0.980
secondary metabolic process GO:0019748 75 0.885
pigment metabolic process GO:0042440 84 0.776
regulation of small gtpase mediated signal transduction GO:0051056 93 0.539
immune effector process GO:0002252 98 0.412
positive regulation of gtp catabolic process GO:0033126 43 0.405
meiotic nuclear division GO:0007126 151 0.363
positive regulation of gtpase activity GO:0043547 43 0.361
melanotic encapsulation of foreign target GO:0035011 30 0.291
ras protein signal transduction GO:0007265 88 0.278
organic hydroxy compound metabolic process GO:1901615 83 0.273
regulation of catalytic activity GO:0050790 185 0.243
regulation of ras protein signal transduction GO:0046578 93 0.242
positive regulation of ras gtpase activity GO:0032320 36 0.238
cell proliferation GO:0008283 299 0.232
purine nucleotide catabolic process GO:0006195 109 0.213
Human
nucleoside phosphate catabolic process GO:1901292 110 0.211
Human
cell motility GO:0048870 251 0.204
defense response GO:0006952 300 0.179
positive regulation of phosphorus metabolic process GO:0010562 139 0.179
dna metabolic process GO:0006259 227 0.174
cellular nitrogen compound catabolic process GO:0044270 165 0.162
Human
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.160
organelle fission GO:0048285 340 0.160
purine containing compound metabolic process GO:0072521 155 0.160
Human
nucleotide catabolic process GO:0009166 109 0.158
Human
positive regulation of phosphate metabolic process GO:0045937 139 0.143
melanization defense response GO:0035006 45 0.142
positive regulation of catabolic process GO:0009896 105 0.134
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.130
Human
organic cyclic compound catabolic process GO:1901361 168 0.127
Human
heterocycle catabolic process GO:0046700 166 0.115
Human
regulation of nucleotide metabolic process GO:0006140 62 0.111
nucleus localization GO:0051647 34 0.111
multi organism behavior GO:0051705 175 0.108
regulation of nucleotide catabolic process GO:0030811 48 0.107
purine nucleotide metabolic process GO:0006163 146 0.104
Human
organonitrogen compound catabolic process GO:1901565 128 0.094
Human
neuroblast proliferation GO:0007405 74 0.091
regulation of hydrolase activity GO:0051336 97 0.091
organophosphate metabolic process GO:0019637 195 0.084
Human
endocytosis GO:0006897 310 0.084
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.081
regulation of phosphate metabolic process GO:0019220 210 0.081
organic substance catabolic process GO:1901575 308 0.080
Human
gtp metabolic process GO:0046039 72 0.080
modification dependent protein catabolic process GO:0019941 78 0.077
nuclear division GO:0000280 332 0.077
glycosyl compound catabolic process GO:1901658 112 0.076
Human
nucleoside triphosphate catabolic process GO:0009143 108 0.075
Human
ribonucleotide catabolic process GO:0009261 109 0.074
Human
intracellular signal transduction GO:0035556 300 0.073
cellular catabolic process GO:0044248 372 0.072
Human
ribonucleoside triphosphate catabolic process GO:0009203 108 0.071
Human
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.071
regulation of intracellular signal transduction GO:1902531 236 0.070
positive regulation of response to stimulus GO:0048584 323 0.068
purine ribonucleoside catabolic process GO:0046130 112 0.068
Human
regulation of catabolic process GO:0009894 170 0.068
regulation of phosphorus metabolic process GO:0051174 210 0.067
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.066
small gtpase mediated signal transduction GO:0007264 88 0.065
vesicle mediated transport GO:0016192 381 0.065
Human
regulation of nucleoside metabolic process GO:0009118 50 0.065
guanosine containing compound metabolic process GO:1901068 74 0.064
purine ribonucleotide catabolic process GO:0009154 109 0.064
Human
organonitrogen compound metabolic process GO:1901564 318 0.062
Human
protein k48 linked ubiquitination GO:0070936 3 0.061
regulation of gtpase activity GO:0043087 44 0.059
secretion GO:0046903 109 0.059
glycosyl compound metabolic process GO:1901657 127 0.057
Human
biological adhesion GO:0022610 138 0.056
regulation of cell cycle process GO:0010564 181 0.055
establishment of localization in cell GO:0051649 402 0.055
Human
regulation of erk1 and erk2 cascade GO:0070372 39 0.053
purine nucleoside catabolic process GO:0006152 112 0.053
Human
regulation of mapk cascade GO:0043408 92 0.052
regulation of meiosis GO:0040020 3 0.051
protein modification process GO:0036211 438 0.051
regulation of molecular function GO:0065009 217 0.050
immune system process GO:0002376 347 0.050
positive regulation of catalytic activity GO:0043085 118 0.049
ommochrome biosynthetic process GO:0006727 19 0.049
catabolic process GO:0009056 409 0.048
Human
cellular macromolecule catabolic process GO:0044265 136 0.047
skin development GO:0043588 65 0.047
positive regulation of cellular catabolic process GO:0031331 95 0.045
positive regulation of nucleotide catabolic process GO:0030813 46 0.044
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.044
positive regulation of nucleotide metabolic process GO:0045981 55 0.044
gtp catabolic process GO:0006184 72 0.043
nucleoside catabolic process GO:0009164 112 0.043
Human
cellular protein modification process GO:0006464 438 0.043
regulation of immune system process GO:0002682 176 0.043
positive regulation of transcription dna templated GO:0045893 266 0.041
carbohydrate derivative catabolic process GO:1901136 118 0.041
Human
protein modification by small protein conjugation or removal GO:0070647 106 0.040
nucleobase containing compound catabolic process GO:0034655 165 0.039
Human
ribonucleotide metabolic process GO:0009259 145 0.038
Human
phosphorylation GO:0016310 294 0.037
neural precursor cell proliferation GO:0061351 75 0.037
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.037
Human
erk1 and erk2 cascade GO:0070371 39 0.036
regulation of rho protein signal transduction GO:0035023 20 0.036
germarium derived egg chamber formation GO:0007293 101 0.036
positive regulation of phosphorylation GO:0042327 87 0.036
ribonucleoside metabolic process GO:0009119 127 0.035
Human
mating behavior GO:0007617 106 0.035
meiotic cell cycle GO:0051321 171 0.035
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.035
positive regulation of molecular function GO:0044093 136 0.034
regulation of phosphorylation GO:0042325 147 0.033
regulation of ras gtpase activity GO:0032318 38 0.033
regulation of gtp catabolic process GO:0033124 44 0.033
purine ribonucleotide metabolic process GO:0009150 145 0.033
Human
regulation of growth GO:0040008 233 0.033
nucleotide metabolic process GO:0009117 161 0.032
Human
imaginal disc derived appendage development GO:0048737 399 0.032
response to external biotic stimulus GO:0043207 293 0.031
regulation of cell cycle GO:0051726 291 0.031
body morphogenesis GO:0010171 2 0.031
purine nucleoside triphosphate catabolic process GO:0009146 108 0.030
Human
regulation of cellular localization GO:0060341 136 0.030
regulation of organelle organization GO:0033043 196 0.029
regulation of purine nucleotide catabolic process GO:0033121 48 0.029
positive regulation of cellular biosynthetic process GO:0031328 316 0.029
signal transduction by phosphorylation GO:0023014 107 0.029
guanosine containing compound catabolic process GO:1901069 74 0.029
negative regulation of gene expression GO:0010629 387 0.028
regulation of hemocyte proliferation GO:0035206 37 0.028
purine nucleoside metabolic process GO:0042278 127 0.028
Human
imaginal disc derived appendage morphogenesis GO:0035114 395 0.028
actin cytoskeleton organization GO:0030036 206 0.028
nucleobase containing small molecule metabolic process GO:0055086 174 0.027
Human
purine nucleoside triphosphate metabolic process GO:0009144 119 0.027
Human
tube development GO:0035295 244 0.027
regulation of cell proliferation GO:0042127 163 0.027
centrosome cycle GO:0007098 137 0.026
centrosome duplication GO:0051298 121 0.026
regulation of nervous system development GO:0051960 248 0.025
oocyte differentiation GO:0009994 145 0.025
localization of cell GO:0051674 257 0.025
cell adhesion GO:0007155 136 0.024
melanin metabolic process GO:0006582 47 0.024
regulation of gene expression epigenetic GO:0040029 128 0.024
response to other organism GO:0051707 293 0.023
sister chromatid segregation GO:0000819 92 0.023
positive regulation of gene expression GO:0010628 290 0.023
small molecule metabolic process GO:0044281 305 0.023
Human
positive regulation of rna biosynthetic process GO:1902680 266 0.022
regulation of purine nucleotide metabolic process GO:1900542 62 0.022
epithelial cell differentiation GO:0030855 322 0.022
chromosome segregation GO:0007059 157 0.022
epithelial cell development GO:0002064 274 0.022
formation of a compartment boundary GO:0060288 4 0.021
regulation of multicellular organismal development GO:2000026 414 0.021
regulation of mitotic cell cycle GO:0007346 190 0.021
single organism catabolic process GO:0044712 228 0.021
Human
single organism behavior GO:0044708 391 0.021
regulation of protein transport GO:0051223 57 0.021
positive regulation of signal transduction GO:0009967 223 0.020
posttranscriptional regulation of gene expression GO:0010608 145 0.020
purine ribonucleoside metabolic process GO:0046128 127 0.020
Human
ribose phosphate metabolic process GO:0019693 145 0.020
Human
organophosphate catabolic process GO:0046434 112 0.020
Human
positive regulation of nucleic acid templated transcription GO:1903508 266 0.020
fertilization GO:0009566 26 0.020
endosomal transport GO:0016197 44 0.020
Human
mitotic nuclear division GO:0007067 213 0.020
cellular macromolecular complex assembly GO:0034622 153 0.019
meiotic cell cycle process GO:1903046 132 0.019
aromatic compound catabolic process GO:0019439 166 0.019
Human
mapk cascade GO:0000165 107 0.019
positive regulation of hydrolase activity GO:0051345 78 0.019
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.018
rho protein signal transduction GO:0007266 14 0.018
immune response GO:0006955 246 0.018
cellular macromolecule localization GO:0070727 220 0.017
positive regulation of cellular component biogenesis GO:0044089 80 0.017
cellular response to dna damage stimulus GO:0006974 223 0.017
positive regulation of erk1 and erk2 cascade GO:0070374 36 0.017
regulation of mitotic cell cycle phase transition GO:1901990 130 0.017
regulation of cell differentiation GO:0045595 302 0.017
positive regulation of nucleoside metabolic process GO:0045979 47 0.017
regulation of localization GO:0032879 275 0.017
negative regulation of cell cycle phase transition GO:1901988 103 0.016
negative regulation of cell death GO:0060548 81 0.016
regionalization GO:0003002 416 0.016
regulation of programmed cell death GO:0043067 152 0.016
response to abiotic stimulus GO:0009628 341 0.016
response to biotic stimulus GO:0009607 294 0.016
regulation of striated muscle contraction GO:0006942 2 0.016
nucleoside phosphate metabolic process GO:0006753 162 0.016
Human
regulation of protein ubiquitination GO:0031396 22 0.015
regulation of receptor mediated endocytosis GO:0048259 9 0.014
death GO:0016265 284 0.014
establishment of protein localization GO:0045184 163 0.014
nucleoside triphosphate metabolic process GO:0009141 120 0.014
Human
positive regulation of mapk cascade GO:0043410 63 0.014
single fertilization GO:0007338 24 0.014
response to organic substance GO:0010033 284 0.014
regulation of protein metabolic process GO:0051246 256 0.014
regulation of cellular protein metabolic process GO:0032268 243 0.014
positive regulation of intracellular signal transduction GO:1902533 116 0.013
response to wounding GO:0009611 94 0.013
synaptic transmission GO:0007268 288 0.013
flight behavior GO:0007629 26 0.013
centrosome organization GO:0051297 163 0.013
positive regulation of neuron projection regeneration GO:0070572 3 0.013
mitotic cell cycle checkpoint GO:0007093 88 0.013
regulation of rab protein signal transduction GO:0032483 7 0.013
growth GO:0040007 359 0.013
mitochondrial membrane organization GO:0007006 3 0.013
negative regulation of response to stimulus GO:0048585 258 0.013
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 1 0.013
positive regulation of signaling GO:0023056 243 0.013
g protein coupled receptor signaling pathway GO:0007186 136 0.012
segmentation GO:0035282 207 0.012
epithelial cell migration GO:0010631 148 0.012
regulation of response to stress GO:0080134 200 0.012
negative regulation of cellular metabolic process GO:0031324 382 0.012
establishment of nucleus localization GO:0040023 26 0.012
regulation of transport GO:0051049 181 0.012
regulation of cell development GO:0060284 215 0.012
carbohydrate derivative metabolic process GO:1901135 217 0.012
Human
central nervous system development GO:0007417 201 0.012
embryo development ending in birth or egg hatching GO:0009792 152 0.012
forebrain development GO:0030900 2 0.012
ribonucleoside catabolic process GO:0042454 112 0.012
Human
ribonucleoside triphosphate metabolic process GO:0009199 119 0.012
Human
carboxylic acid metabolic process GO:0019752 92 0.012
protein transport GO:0015031 155 0.012
positive regulation of biosynthetic process GO:0009891 316 0.011
regulation of cell cycle phase transition GO:1901987 130 0.011
cell migration GO:0016477 238 0.011
mating GO:0007618 120 0.011
regulation of cellular catabolic process GO:0031329 157 0.011
tissue morphogenesis GO:0048729 297 0.011
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.011
regulation of protein modification process GO:0031399 112 0.011
blastoderm segmentation GO:0007350 159 0.011
cellular ketone metabolic process GO:0042180 24 0.011
protein localization GO:0008104 284 0.011
dna repair GO:0006281 54 0.011
developmental growth GO:0048589 280 0.011
post embryonic appendage morphogenesis GO:0035120 385 0.011
imaginal disc derived wing morphogenesis GO:0007476 337 0.011
ocellus pigment metabolic process GO:0046158 19 0.011
regulation of cell division GO:0051302 72 0.010
cell maturation GO:0048469 144 0.010
notch signaling pathway GO:0007219 120 0.010
lipid metabolic process GO:0006629 121 0.010
cardiovascular system development GO:0072358 82 0.010
respiratory system development GO:0060541 213 0.010
adult locomotory behavior GO:0008344 76 0.010
response to oxidative stress GO:0006979 86 0.010
stem cell division GO:0017145 69 0.010

RhoBTB disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org