Drosophila melanogaster

59 known processes

Arr1 (Dmel_CG5711)

Arrestin 1

(Aliases: PRII,Arr,Dmel\CG5711,ArrA,Dmarrestin,DA,DS-Ag,3H10,FBgn0000120,ARR1,arr1,CG5711,DmArr1)

Arr1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular response to radiation GO:0071478 52 0.841
detection of light stimulus GO:0009583 58 0.803
phototransduction visible light GO:0007603 27 0.768
detection of stimulus GO:0051606 156 0.753
g protein coupled receptor signaling pathway GO:0007186 136 0.725
cellular response to uv GO:0034644 12 0.723
cellular response to light stimulus GO:0071482 37 0.710
compound eye photoreceptor development GO:0042051 78 0.636
photoreceptor cell differentiation GO:0046530 170 0.623
rhodopsin mediated signaling pathway GO:0016056 21 0.515
phototransduction uv GO:0007604 5 0.503
rhabdomere development GO:0042052 38 0.502
detection of visible light GO:0009584 38 0.457
regulation of multicellular organismal development GO:2000026 414 0.435
Fly
eye photoreceptor cell development GO:0042462 81 0.432
sensory organ morphogenesis GO:0090596 260 0.418
central nervous system development GO:0007417 201 0.398
Rat
eye photoreceptor cell differentiation GO:0001754 145 0.370
phototransduction GO:0007602 52 0.364
response to light intensity GO:0009642 6 0.362
Fly
regulation of organ morphogenesis GO:2000027 78 0.354
response to radiation GO:0009314 155 0.339
light induced release of internally sequestered calcium ion GO:0008377 1 0.335
compound eye photoreceptor cell differentiation GO:0001751 140 0.299
entrainment of circadian clock by photoperiod GO:0043153 9 0.297
photoreceptor cell development GO:0042461 96 0.297
neurological system process GO:0050877 358 0.288
Rat Fly
response to abiotic stimulus GO:0009628 341 0.283
eye development GO:0001654 323 0.278
thermotaxis GO:0043052 16 0.251
regulation of intracellular signal transduction GO:1902531 236 0.228
Rat
regulation of cell differentiation GO:0045595 302 0.222
Fly
negative regulation of gene expression GO:0010629 387 0.219
Rat
negative regulation of rna biosynthetic process GO:1902679 240 0.208
deactivation of rhodopsin mediated signaling GO:0016059 17 0.205
cellular response to abiotic stimulus GO:0071214 58 0.204
negative regulation of response to stimulus GO:0048585 258 0.202
purine nucleoside metabolic process GO:0042278 127 0.199
Rat
transcription from rna polymerase ii promoter GO:0006366 368 0.193
Rat
apoptotic signaling pathway GO:0097190 27 0.188
Rat
regulation of rhodopsin mediated signaling pathway GO:0022400 17 0.182
regulation of sequestering of calcium ion GO:0051282 3 0.180
response to light stimulus GO:0009416 124 0.177
eye morphogenesis GO:0048592 260 0.176
negative regulation of cell communication GO:0010648 223 0.172
regulation of programmed cell death GO:0043067 152 0.172
Rat
retinal cell programmed cell death GO:0046666 25 0.162
regulation of cell death GO:0010941 173 0.156
Rat
regulation of anatomical structure morphogenesis GO:0022603 242 0.149
regulation of compound eye retinal cell programmed cell death GO:0046669 18 0.143
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.136
Rat
phospholipase c activating rhodopsin mediated signaling pathway GO:0030265 1 0.135
compound eye development GO:0048749 307 0.125
cellular metal ion homeostasis GO:0006875 31 0.122
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.112
negative regulation of cellular metabolic process GO:0031324 382 0.110
Rat Fly
proteolysis GO:0006508 192 0.109
Rat
negative regulation of cell differentiation GO:0045596 143 0.106
Fly
negative regulation of homeostatic process GO:0032845 2 0.106
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.105
Rat
negative regulation of cell death GO:0060548 81 0.105
Rat
death GO:0016265 284 0.105
Rat
response to temperature stimulus GO:0009266 106 0.104
Rat
negative regulation of signaling GO:0023057 219 0.103
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.103
Rat
developmental pigmentation GO:0048066 68 0.103
protein ubiquitination GO:0016567 70 0.102
Rat
regulation of response to external stimulus GO:0032101 115 0.101
regulation of localization GO:0032879 275 0.099
Rat
regulation of organelle organization GO:0033043 196 0.097
Rat
cellular calcium ion homeostasis GO:0006874 21 0.091
compound eye morphogenesis GO:0001745 249 0.091
negative regulation of developmental process GO:0051093 201 0.091
Fly
single organism behavior GO:0044708 391 0.090
Fly
locomotory behavior GO:0007626 176 0.089
Fly
negative regulation of cellular biosynthetic process GO:0031327 277 0.087
regulation of cell development GO:0060284 215 0.086
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.084
Rat
divalent inorganic cation homeostasis GO:0072507 29 0.084
purine containing compound metabolic process GO:0072521 155 0.082
Rat
purine ribonucleoside metabolic process GO:0046128 127 0.081
Rat
negative regulation of transcription dna templated GO:0045892 237 0.078
detection of abiotic stimulus GO:0009582 66 0.077
negative regulation of biosynthetic process GO:0009890 277 0.077
optokinetic behavior GO:0007634 3 0.074
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 10 0.074
synapse assembly GO:0007416 143 0.074
cellular amine metabolic process GO:0044106 12 0.074
cell death GO:0008219 279 0.073
Rat
cellular ketone metabolic process GO:0042180 24 0.072
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.071
Rat
absorption of uv light GO:0016039 1 0.071
positive regulation of response to stimulus GO:0048584 323 0.070
Rat
negative regulation of programmed cell death GO:0043069 72 0.070
Rat
negative regulation of rna metabolic process GO:0051253 251 0.070
ribonucleotide catabolic process GO:0009261 109 0.070
Rat
ribonucleoside metabolic process GO:0009119 127 0.069
Rat
immune response GO:0006955 246 0.069
regulation of phosphate metabolic process GO:0019220 210 0.068
Rat Fly
regulation of apoptotic process GO:0042981 130 0.068
Rat
programmed cell death GO:0012501 257 0.068
Rat
nucleobase containing compound catabolic process GO:0034655 165 0.067
Rat
protein transport GO:0015031 155 0.066
negative regulation of intracellular signal transduction GO:1902532 57 0.065
Rat
regulation of apoptotic signaling pathway GO:2001233 10 0.065
Rat
ribonucleoside catabolic process GO:0042454 112 0.064
Rat
catabolic process GO:0009056 409 0.063
Rat
guanosine containing compound catabolic process GO:1901069 74 0.062
Rat
regulation of protein metabolic process GO:0051246 256 0.062
Rat Fly
detection of external stimulus GO:0009581 66 0.061
protein phosphorylation GO:0006468 169 0.060
Rat Fly
energy taxis GO:0009453 21 0.060
purine nucleoside triphosphate catabolic process GO:0009146 108 0.059
Rat
cellular protein localization GO:0034613 160 0.059
nucleoside triphosphate catabolic process GO:0009143 108 0.058
Rat
intrinsic apoptotic signaling pathway GO:0097193 16 0.057
negative regulation of cell development GO:0010721 62 0.057
regulation of cellular protein metabolic process GO:0032268 243 0.057
Rat Fly
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.056
Rat
phosphorylation GO:0016310 294 0.056
Rat Fly
positive regulation of cellular biosynthetic process GO:0031328 316 0.055
Rat
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.055
nucleoside phosphate catabolic process GO:1901292 110 0.055
Rat
positive regulation of phosphate metabolic process GO:0045937 139 0.054
Rat
amine metabolic process GO:0009308 12 0.054
regulation of cellular amine metabolic process GO:0033238 3 0.054
regulation of cellular response to stress GO:0080135 89 0.054
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.054
homeostatic process GO:0042592 199 0.053
positive regulation of protein metabolic process GO:0051247 128 0.053
Rat Fly
positive regulation of biosynthetic process GO:0009891 316 0.053
Rat
cellular response to chemical stimulus GO:0070887 199 0.052
organophosphate metabolic process GO:0019637 195 0.049
Rat
peptidyl amino acid modification GO:0018193 105 0.048
Rat Fly
response to organic substance GO:0010033 284 0.048
positive regulation of macromolecule metabolic process GO:0010604 405 0.048
Rat Fly
nucleoside triphosphate metabolic process GO:0009141 120 0.046
Rat
olfactory behavior GO:0042048 97 0.046
protein modification by small protein conjugation GO:0032446 79 0.046
Rat
gtp catabolic process GO:0006184 72 0.046
Rat
sensory perception GO:0007600 196 0.045
Rat Fly
carbohydrate derivative catabolic process GO:1901136 118 0.045
Rat
organic substance catabolic process GO:1901575 308 0.044
Rat
glycosyl compound metabolic process GO:1901657 127 0.044
Rat
glycosyl compound catabolic process GO:1901658 112 0.044
Rat
positive regulation of signaling GO:0023056 243 0.043
Rat
purine ribonucleotide catabolic process GO:0009154 109 0.043
Rat
regulation of g protein coupled receptor protein signaling pathway GO:0008277 23 0.043
cellular catabolic process GO:0044248 372 0.042
Rat
photoperiodism GO:0009648 10 0.042
small molecule metabolic process GO:0044281 305 0.042
Rat
negative regulation of multicellular organismal process GO:0051241 142 0.041
Fly
taxis GO:0042330 304 0.041
regulation of phosphorylation GO:0042325 147 0.041
Rat Fly
organic cyclic compound catabolic process GO:1901361 168 0.041
Rat
purine nucleoside catabolic process GO:0006152 112 0.039
Rat
adult behavior GO:0030534 137 0.039
regulation of ion homeostasis GO:2000021 5 0.039
maintenance of location GO:0051235 73 0.039
metal ion homeostasis GO:0055065 44 0.038
regionalization GO:0003002 416 0.038
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.038
Rat
carboxylic acid metabolic process GO:0019752 92 0.038
response to other organism GO:0051707 293 0.038
head development GO:0060322 135 0.038
Rat
immune system process GO:0002376 347 0.037
Fly
nucleoside metabolic process GO:0009116 127 0.037
Rat
positive regulation of signal transduction GO:0009967 223 0.037
Rat
response to endoplasmic reticulum stress GO:0034976 28 0.036
nucleobase containing small molecule metabolic process GO:0055086 174 0.036
Rat
negative regulation of sequestering of calcium ion GO:0051283 2 0.036
negative regulation of signal transduction GO:0009968 206 0.036
organonitrogen compound metabolic process GO:1901564 318 0.036
Rat
purine nucleotide metabolic process GO:0006163 146 0.035
Rat
cellular protein modification process GO:0006464 438 0.035
Rat Fly
regulation of mitochondrion organization GO:0010821 12 0.035
Rat
regulation of retinal cell programmed cell death GO:0046668 18 0.035
ribonucleoside triphosphate catabolic process GO:0009203 108 0.035
Rat
brain development GO:0007420 120 0.035
Rat
carbohydrate derivative metabolic process GO:1901135 217 0.035
Rat
membrane organization GO:0061024 112 0.034
synapse organization GO:0050808 196 0.033
establishment of localization in cell GO:0051649 402 0.033
signal transduction by phosphorylation GO:0023014 107 0.032
Rat
cellular cation homeostasis GO:0030003 38 0.032
positive regulation of cellular amine metabolic process GO:0033240 0 0.032
multi multicellular organism process GO:0044706 123 0.032
regulation of protein phosphorylation GO:0001932 64 0.031
Rat Fly
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.031
Rat
protein modification process GO:0036211 438 0.031
Rat Fly
dorsal ventral pattern formation GO:0009953 133 0.031
positive regulation of nucleic acid templated transcription GO:1903508 266 0.030
Rat
negative regulation of organelle organization GO:0010639 56 0.030
Rat
purine nucleotide catabolic process GO:0006195 109 0.030
Rat
nucleoside catabolic process GO:0009164 112 0.030
Rat
regulation of cell morphogenesis GO:0022604 163 0.029
sensory perception of sound GO:0007605 56 0.028
Fly
regulation of growth GO:0040008 233 0.028
single organism intracellular transport GO:1902582 207 0.028
positive regulation of gene expression GO:0010628 290 0.028
Rat
regulation of immune system process GO:0002682 176 0.028
Fly
neuromuscular junction development GO:0007528 149 0.028
nucleoside phosphate metabolic process GO:0006753 162 0.028
Rat
organonitrogen compound catabolic process GO:1901565 128 0.028
Rat
pigmentation GO:0043473 75 0.028
organic acid metabolic process GO:0006082 103 0.028
purine ribonucleoside catabolic process GO:0046130 112 0.027
Rat
single organism catabolic process GO:0044712 228 0.027
Rat
chemosensory behavior GO:0007635 106 0.027
nucleotide metabolic process GO:0009117 161 0.027
Rat
glycoprotein biosynthetic process GO:0009101 41 0.027
cellular nitrogen compound catabolic process GO:0044270 165 0.027
Rat
positive regulation of rna metabolic process GO:0051254 271 0.027
Rat
response to uv GO:0009411 24 0.027
positive regulation of cell communication GO:0010647 250 0.026
Rat
absorption of visible light GO:0016038 1 0.026
protein localization GO:0008104 284 0.026
regulation of catabolic process GO:0009894 170 0.026
Rat
organophosphate catabolic process GO:0046434 112 0.026
Rat
negative regulation of erk1 and erk2 cascade GO:0070373 3 0.026
Rat
cellular macromolecule localization GO:0070727 220 0.026
learning GO:0007612 75 0.025
positive regulation of calcium ion transport GO:0051928 4 0.025
Rat
single organism carbohydrate metabolic process GO:0044723 72 0.025
regulation of cell cycle GO:0051726 291 0.025
regulation of cysteine type endopeptidase activity GO:2000116 27 0.025
Rat
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.025
regulation of protein kinase activity GO:0045859 51 0.024
Rat Fly
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.024
regulation of gtpase activity GO:0043087 44 0.024
Rat
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.024
Rat
regulation of cellular catabolic process GO:0031329 157 0.024
Rat
imaginal disc derived appendage development GO:0048737 399 0.024
single organism cellular localization GO:1902580 180 0.024
positive regulation of molecular function GO:0044093 136 0.024
Rat
purine ribonucleotide metabolic process GO:0009150 145 0.024
Rat
tissue homeostasis GO:0001894 36 0.023
dendrite development GO:0016358 204 0.023
response to external biotic stimulus GO:0043207 293 0.023
regulation of cellular localization GO:0060341 136 0.023
regulation of nucleotide metabolic process GO:0006140 62 0.023
Rat
intracellular transport GO:0046907 228 0.023
organic substance transport GO:0071702 257 0.022
intracellular signal transduction GO:0035556 300 0.022
Rat
detection of uv GO:0009589 6 0.022
response to oxygen containing compound GO:1901700 200 0.022
translation GO:0006412 69 0.022
multicellular organismal homeostasis GO:0048871 41 0.022
regulation of protein modification process GO:0031399 112 0.022
Rat Fly
negative regulation of cellular component organization GO:0051129 108 0.022
Rat
cell maturation GO:0048469 144 0.022
epithelial cell differentiation GO:0030855 322 0.021
ribonucleotide metabolic process GO:0009259 145 0.021
Rat
sensory perception of chemical stimulus GO:0007606 116 0.021
negative regulation of nucleic acid templated transcription GO:1903507 240 0.021
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.021
Rat
cellular response to organic substance GO:0071310 132 0.021
adult locomotory behavior GO:0008344 76 0.021
cellular homeostasis GO:0019725 80 0.021
optomotor response GO:0071632 3 0.020
positive regulation of transcription dna templated GO:0045893 266 0.020
Rat
gtp metabolic process GO:0046039 72 0.020
Rat
peptidyl tyrosine modification GO:0018212 24 0.020
Rat Fly
cellular amino acid metabolic process GO:0006520 61 0.020
aromatic compound catabolic process GO:0019439 166 0.020
Rat
calcium ion homeostasis GO:0055074 23 0.020
entrainment of circadian clock GO:0009649 16 0.020
cellular divalent inorganic cation homeostasis GO:0072503 23 0.020
protein heterooligomerization GO:0051291 4 0.020
visual perception GO:0007601 9 0.019
Rat
phototaxis GO:0042331 21 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.019
negative regulation of compound eye retinal cell programmed cell death GO:0046673 7 0.019
regulation of transport GO:0051049 181 0.019
Rat
positive regulation of catalytic activity GO:0043085 118 0.018
Rat
post embryonic appendage morphogenesis GO:0035120 385 0.018
oxoacid metabolic process GO:0043436 103 0.018
anatomical structure homeostasis GO:0060249 97 0.018
regulation of catalytic activity GO:0050790 185 0.018
Rat Fly
chromosome organization GO:0051276 360 0.018
chemical homeostasis GO:0048878 92 0.018
positive regulation of phosphorylation GO:0042327 87 0.018
Rat
ubiquitin dependent protein catabolic process GO:0006511 78 0.018
detection of stimulus involved in sensory perception GO:0050906 92 0.018
Rat
wing disc morphogenesis GO:0007472 344 0.018
cellular chemical homeostasis GO:0055082 40 0.017
purine containing compound catabolic process GO:0072523 112 0.017
Rat
modification dependent macromolecule catabolic process GO:0043632 79 0.017
body morphogenesis GO:0010171 2 0.017
negative regulation of synapse assembly GO:0051964 39 0.017
positive regulation of protein phosphorylation GO:0001934 34 0.017
Rat
positive regulation of cellular protein metabolic process GO:0032270 118 0.016
Rat Fly
protein modification by small protein conjugation or removal GO:0070647 106 0.016
Rat Fly
mitotic nuclear division GO:0007067 213 0.016
carbohydrate metabolic process GO:0005975 82 0.016
morphogenesis of an epithelium GO:0002009 276 0.016
developmental programmed cell death GO:0010623 138 0.016
regulation of phosphorus metabolic process GO:0051174 210 0.016
Rat Fly
mapk cascade GO:0000165 107 0.016
Rat
protein complex assembly GO:0006461 200 0.015
positive regulation of phosphorus metabolic process GO:0010562 139 0.015
Rat
heterocycle catabolic process GO:0046700 166 0.015
Rat
endocytosis GO:0006897 310 0.015
proteasomal protein catabolic process GO:0010498 59 0.015
negative regulation of cellular protein metabolic process GO:0032269 85 0.015
Rat Fly
regulation of purine nucleotide metabolic process GO:1900542 62 0.015
Rat
single organism biosynthetic process GO:0044711 206 0.015
cellular protein catabolic process GO:0044257 83 0.015
phagocytosis GO:0006909 215 0.015
carbohydrate derivative biosynthetic process GO:1901137 85 0.015
regulation of nucleoside metabolic process GO:0009118 50 0.015
Rat
positive regulation of transport GO:0051050 92 0.014
Rat
cation homeostasis GO:0055080 51 0.014
positive regulation of hydrolase activity GO:0051345 78 0.014
Rat
cellular ion homeostasis GO:0006873 39 0.014
vesicle mediated transport GO:0016192 381 0.014
regulation of translation GO:0006417 56 0.014
glycoprotein metabolic process GO:0009100 41 0.014
epithelial cell development GO:0002064 274 0.014
rhythmic process GO:0048511 106 0.014
Rat
regulation of intracellular protein transport GO:0033157 46 0.014
asymmetric neuroblast division GO:0055059 33 0.014
synaptic growth at neuromuscular junction GO:0051124 119 0.014
forebrain development GO:0030900 2 0.014
mitochondrion organization GO:0007005 65 0.014
Rat
modification dependent protein catabolic process GO:0019941 78 0.014
neuronal stem cell division GO:0036445 35 0.014
protein catabolic process GO:0030163 101 0.014
regulation of transferase activity GO:0051338 58 0.014
Rat Fly
sensory perception of mechanical stimulus GO:0050954 72 0.014
Fly
cell division GO:0051301 248 0.013
macromolecular complex assembly GO:0065003 256 0.013
regulation of cellular ketone metabolic process GO:0010565 3 0.013
photoreceptor cell maintenance GO:0045494 11 0.013
retina homeostasis GO:0001895 13 0.013
camera type eye development GO:0043010 4 0.013
regulation of nervous system development GO:0051960 248 0.013
ribonucleoside triphosphate metabolic process GO:0009199 119 0.013
Rat
morphogenesis of a polarized epithelium GO:0001738 93 0.013
positive regulation of intracellular signal transduction GO:1902533 116 0.013
Rat
innate immune response GO:0045087 144 0.013
ion transport GO:0006811 145 0.013
Rat
peptidyl threonine modification GO:0018210 3 0.013
sequestering of calcium ion GO:0051208 5 0.013
nucleotide catabolic process GO:0009166 109 0.013
Rat
positive regulation of transferase activity GO:0051347 26 0.013
Rat
negative regulation of cellular catabolic process GO:0031330 34 0.013
Rat
regulation of mitotic cell cycle GO:0007346 190 0.012
appendage morphogenesis GO:0035107 397 0.012
protein transmembrane transport GO:0071806 4 0.012
morphogenesis of embryonic epithelium GO:0016331 94 0.012
oocyte differentiation GO:0009994 145 0.012
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.012
eye pigment metabolic process GO:0042441 33 0.012
response to hexose GO:0009746 3 0.012
purine nucleoside triphosphate metabolic process GO:0009144 119 0.012
Rat
appendage development GO:0048736 401 0.012
metarhodopsin inactivation GO:0016060 5 0.012
compound eye retinal cell programmed cell death GO:0046667 23 0.012
ion homeostasis GO:0050801 55 0.012
establishment of tissue polarity GO:0007164 87 0.012
cellular response to extracellular stimulus GO:0031668 64 0.011
positive regulation of protein modification process GO:0031401 58 0.011
Rat Fly
response to biotic stimulus GO:0009607 294 0.011
activation of protein kinase activity GO:0032147 12 0.011
Rat
divalent inorganic cation transport GO:0072511 30 0.011
Rat
digestive tract development GO:0048565 149 0.011
Fly
endomembrane system organization GO:0010256 119 0.011
immune effector process GO:0002252 98 0.011
regulation of cellular component biogenesis GO:0044087 201 0.011
regulation of dna metabolic process GO:0051052 34 0.011
Rat
imaginal disc derived appendage morphogenesis GO:0035114 395 0.011
chromatin organization GO:0006325 207 0.011
protein complex biogenesis GO:0070271 201 0.011
protein localization to nucleus GO:0034504 55 0.010
sensory perception of smell GO:0007608 80 0.010
regulation of proteolysis GO:0030162 87 0.010
Rat
response to nitrogen compound GO:1901698 90 0.010
autophagy GO:0006914 108 0.010
pigment metabolic process GO:0042440 84 0.010
protein glycosylation GO:0006486 32 0.010
macromolecule catabolic process GO:0009057 161 0.010
mesenchymal cell development GO:0014031 1 0.010

Arr1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.042
Human
disease of anatomical entity DOID:7 0 0.042
Human
nervous system disease DOID:863 0 0.042
Human
eye and adnexa disease DOID:1492 0 0.030
Human
eye disease DOID:5614 0 0.024
Human
disease of cellular proliferation DOID:14566 0 0.018
cancer DOID:162 0 0.012