Drosophila melanogaster

85 known processes

Npc1a (Dmel_CG5722)

Niemann-Pick type C-1a

(Aliases: DmNPC,dmNPC1,NPC1a,dnpc1a,NPC1,CG5722,dNPC1a,Npc1,Npc1_Dm,npc1,dNPC1,npc1a,Dmel\CG5722,dncp1a)

Npc1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
male gamete generation GO:0048232 201 0.922
establishment of localization in cell GO:0051649 402 0.905
Mouse
spermatogenesis GO:0007283 200 0.892
metal ion homeostasis GO:0055065 44 0.858
cellularization GO:0007349 90 0.839
cation homeostasis GO:0055080 51 0.816
cation transport GO:0006812 110 0.796
taxis GO:0042330 304 0.756
intracellular transport GO:0046907 228 0.728
Mouse
spermatid differentiation GO:0048515 114 0.720
protein complex assembly GO:0006461 200 0.620
chemical homeostasis GO:0048878 92 0.616
Human Mouse Worm
ion homeostasis GO:0050801 55 0.594
morphogenesis of an epithelium GO:0002009 276 0.559
sperm individualization GO:0007291 48 0.558
cellular macromolecule localization GO:0070727 220 0.544
Human
spermatid development GO:0007286 98 0.535
axon development GO:0061564 297 0.507
cation transmembrane transport GO:0098655 88 0.503
organonitrogen compound metabolic process GO:1901564 318 0.470
regulation of multicellular organismal development GO:2000026 414 0.463
cellular protein modification process GO:0006464 438 0.426
Human Mouse
steroid biosynthetic process GO:0006694 16 0.416
regulation of cellular protein metabolic process GO:0032268 243 0.405
ion transport GO:0006811 145 0.399
developmental growth GO:0048589 280 0.398
protein complex biogenesis GO:0070271 201 0.393
cell maturation GO:0048469 144 0.367
sensory perception of mechanical stimulus GO:0050954 72 0.367
epithelial cell differentiation GO:0030855 322 0.356
single organism membrane organization GO:0044802 93 0.336
Human
aging GO:0007568 143 0.332
metal ion transport GO:0030001 74 0.327
endomembrane system organization GO:0010256 119 0.316
regulation of localization GO:0032879 275 0.315
regulation of microtubule cytoskeleton organization GO:0070507 41 0.308
homeostatic process GO:0042592 199 0.302
Human Mouse Worm
regulation of microtubule based process GO:0032886 49 0.295
mitotic g2 dna damage checkpoint GO:0007095 69 0.292
growth GO:0040007 359 0.285
Worm
protein modification process GO:0036211 438 0.261
Human Mouse
regulation of synapse structure and activity GO:0050803 128 0.257
positive regulation of response to stimulus GO:0048584 323 0.256
ion transmembrane transport GO:0034220 122 0.249
central nervous system development GO:0007417 201 0.248
defense response GO:0006952 300 0.244
peptidyl amino acid modification GO:0018193 105 0.238
cellular response to chemical stimulus GO:0070887 199 0.235
Mouse
protein localization GO:0008104 284 0.219
Human
open tracheal system development GO:0007424 204 0.208
lateral inhibition GO:0046331 206 0.203
locomotory behavior GO:0007626 176 0.195
Mouse
negative regulation of cell cycle phase transition GO:1901988 103 0.195
regulation of cellular component biogenesis GO:0044087 201 0.193
microtubule organizing center organization GO:0031023 168 0.193
cellular protein localization GO:0034613 160 0.190
Human
detection of stimulus GO:0051606 156 0.187
respiratory system development GO:0060541 213 0.185
germarium derived egg chamber formation GO:0007293 101 0.185
positive regulation of signaling GO:0023056 243 0.184
establishment of organelle localization GO:0051656 122 0.181
response to abiotic stimulus GO:0009628 341 0.178
axonogenesis GO:0007409 290 0.176
single organism intracellular transport GO:1902582 207 0.173
Mouse
anterior posterior axis specification GO:0009948 109 0.170
axon guidance GO:0007411 233 0.168
ribonucleotide metabolic process GO:0009259 145 0.166
cell cycle checkpoint GO:0000075 95 0.163
endocytosis GO:0006897 310 0.162
Mouse
developmental maturation GO:0021700 172 0.160
macromolecular complex assembly GO:0065003 256 0.160
chemotaxis GO:0006935 249 0.159
cell migration GO:0016477 238 0.158
membrane organization GO:0061024 112 0.157
Human
embryonic morphogenesis GO:0048598 206 0.157
immune system process GO:0002376 347 0.155
purine nucleoside triphosphate metabolic process GO:0009144 119 0.152
regulation of transport GO:0051049 181 0.151
protein localization to organelle GO:0033365 82 0.149
lipid localization GO:0010876 54 0.149
segmentation GO:0035282 207 0.146
epithelial cell migration GO:0010631 148 0.145
protein catabolic process GO:0030163 101 0.145
developmental growth involved in morphogenesis GO:0060560 65 0.144
sensory perception GO:0007600 196 0.140
cellular ion homeostasis GO:0006873 39 0.136
regulation of secretion by cell GO:1903530 39 0.135
positive regulation of cellular component organization GO:0051130 156 0.133
regulation of endopeptidase activity GO:0052548 36 0.130
regulation of cell death GO:0010941 173 0.130
tissue morphogenesis GO:0048729 297 0.128
protein maturation GO:0051604 71 0.127
synaptic transmission GO:0007268 288 0.126
secretion GO:0046903 109 0.126
macromolecule catabolic process GO:0009057 161 0.125
circulatory system development GO:0072359 82 0.121
lipid metabolic process GO:0006629 121 0.119
negative regulation of nervous system development GO:0051961 92 0.119
cellular cation homeostasis GO:0030003 38 0.116
small molecule metabolic process GO:0044281 305 0.115
centrosome organization GO:0051297 163 0.111
cell death GO:0008219 279 0.111
regionalization GO:0003002 416 0.109
organelle localization GO:0051640 148 0.109
regulation of synapse organization GO:0050807 110 0.109
neurological system process GO:0050877 358 0.107
organophosphate metabolic process GO:0019637 195 0.107
golgi organization GO:0007030 66 0.103
g2 dna damage checkpoint GO:0031572 69 0.102
mitotic g2 m transition checkpoint GO:0044818 70 0.098
sensory perception of chemical stimulus GO:0007606 116 0.098
protein transport GO:0015031 155 0.098
cellular hormone metabolic process GO:0034754 23 0.097
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.094
establishment or maintenance of apical basal cell polarity GO:0035088 34 0.094
regulation of cysteine type endopeptidase activity GO:2000116 27 0.092
purine containing compound metabolic process GO:0072521 155 0.092
multicellular organismal aging GO:0010259 140 0.090
neuron projection guidance GO:0097485 241 0.090
protein localization to nucleus GO:0034504 55 0.088
anatomical structure homeostasis GO:0060249 97 0.085
organic substance transport GO:0071702 257 0.083
single organism cellular localization GO:1902580 180 0.083
Human
positive regulation of catalytic activity GO:0043085 118 0.083
response to wounding GO:0009611 94 0.081
microtubule based movement GO:0007018 51 0.081
defense response to other organism GO:0098542 225 0.079
establishment or maintenance of cell polarity GO:0007163 167 0.078
regulation of molecular function GO:0065009 217 0.078
regulation of protein transport GO:0051223 57 0.077
catabolic process GO:0009056 409 0.076
Human Mouse
positive regulation of protein metabolic process GO:0051247 128 0.074
immune response GO:0006955 246 0.072
lipid biosynthetic process GO:0008610 46 0.072
purine ribonucleoside metabolic process GO:0046128 127 0.072
inorganic ion transmembrane transport GO:0098660 73 0.071
purine nucleotide metabolic process GO:0006163 146 0.070
steroid metabolic process GO:0008202 20 0.069
glycosyl compound metabolic process GO:1901657 127 0.069
body morphogenesis GO:0010171 2 0.069
mitotic dna damage checkpoint GO:0044773 74 0.068
death GO:0016265 284 0.068
negative regulation of cellular metabolic process GO:0031324 382 0.067
Mouse
positive regulation of cellular protein metabolic process GO:0032270 118 0.066
positive regulation of cell communication GO:0010647 250 0.065
cellular catabolic process GO:0044248 372 0.064
Human Mouse
epithelium migration GO:0090132 148 0.064
organic cyclic compound catabolic process GO:1901361 168 0.063
regulation of synapse assembly GO:0051963 94 0.063
regulation of cell differentiation GO:0045595 302 0.062
cell junction organization GO:0034330 57 0.062
regulation of proteolysis GO:0030162 87 0.062
regulation of cell cycle GO:0051726 291 0.062
cytoplasmic transport GO:0016482 130 0.062
retina development in camera type eye GO:0060041 4 0.062
maintenance of location GO:0051235 73 0.061
regulation of nervous system development GO:0051960 248 0.061
spindle organization GO:0007051 253 0.060
dendrite development GO:0016358 204 0.059
negative regulation of mitotic cell cycle GO:0045930 109 0.058
regulation of cellular localization GO:0060341 136 0.058
tissue migration GO:0090130 155 0.057
positive regulation of hydrolase activity GO:0051345 78 0.057
organic acid metabolic process GO:0006082 103 0.056
Mouse
regulation of programmed cell death GO:0043067 152 0.056
programmed cell death GO:0012501 257 0.055
organic substance catabolic process GO:1901575 308 0.055
regulation of intracellular transport GO:0032386 64 0.055
negative regulation of multicellular organismal process GO:0051241 142 0.054
tube development GO:0035295 244 0.054
determination of adult lifespan GO:0008340 137 0.054
oocyte differentiation GO:0009994 145 0.053
response to radiation GO:0009314 155 0.052
carbohydrate derivative metabolic process GO:1901135 217 0.051
Human Mouse
asymmetric protein localization GO:0008105 33 0.051
regulation of apoptotic process GO:0042981 130 0.051
ameboidal type cell migration GO:0001667 151 0.051
axis specification GO:0009798 167 0.051
embryonic development via the syncytial blastoderm GO:0001700 148 0.050
embryonic pattern specification GO:0009880 174 0.050
cellular homeostasis GO:0019725 80 0.050
intracellular protein transport GO:0006886 104 0.050
positive regulation of molecular function GO:0044093 136 0.050
cytoplasm organization GO:0007028 64 0.049
positive regulation of apoptotic signaling pathway GO:2001235 4 0.049
peptidyl tyrosine phosphorylation GO:0018108 24 0.048
positive regulation of signal transduction GO:0009967 223 0.047
protein processing GO:0016485 68 0.047
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.047
dendrite morphogenesis GO:0048813 199 0.047
positive regulation of programmed cell death GO:0043068 62 0.047
regulation of catalytic activity GO:0050790 185 0.046
regulation of hormone levels GO:0010817 40 0.046
blastoderm segmentation GO:0007350 159 0.046
cellular macromolecular complex assembly GO:0034622 153 0.046
protein targeting to nucleus GO:0044744 51 0.045
establishment of protein localization GO:0045184 163 0.045
Human
organic hydroxy compound metabolic process GO:1901615 83 0.045
sleep GO:0030431 49 0.045
regulation of phosphate metabolic process GO:0019220 210 0.045
forebrain development GO:0030900 2 0.044
lipid storage GO:0019915 38 0.044
nucleoside triphosphate metabolic process GO:0009141 120 0.044
negative regulation of growth GO:0045926 84 0.043
negative regulation of synaptic growth at neuromuscular junction GO:0045886 39 0.043
cellular amine metabolic process GO:0044106 12 0.043
proteolysis GO:0006508 192 0.043
regulation of secretion GO:0051046 44 0.042
epithelial cell development GO:0002064 274 0.042
circadian rhythm GO:0007623 105 0.042
regulation of growth GO:0040008 233 0.042
Worm
mitotic cell cycle checkpoint GO:0007093 88 0.041
cellular ketone metabolic process GO:0042180 24 0.041
glycosyl compound catabolic process GO:1901658 112 0.041
cellular metal ion homeostasis GO:0006875 31 0.040
nucleoside phosphate catabolic process GO:1901292 110 0.040
neuromuscular junction development GO:0007528 149 0.040
regulation of intracellular signal transduction GO:1902531 236 0.040
regulation of organelle organization GO:0033043 196 0.040
tube morphogenesis GO:0035239 191 0.039
regulation of protein metabolic process GO:0051246 256 0.039
eye development GO:0001654 323 0.038
imaginal disc derived appendage development GO:0048737 399 0.038
cell cycle phase transition GO:0044770 140 0.038
inorganic cation transmembrane transport GO:0098662 61 0.038
cellular response to dna damage stimulus GO:0006974 223 0.038
cell motility GO:0048870 251 0.037
regulation of cell development GO:0060284 215 0.037
single organism nuclear import GO:1902593 51 0.037
head development GO:0060322 135 0.036
positive regulation of cell death GO:0010942 69 0.036
regulation of protein localization GO:0032880 76 0.035
nuclear import GO:0051170 51 0.035
purine nucleotide catabolic process GO:0006195 109 0.035
pigmentation GO:0043473 75 0.034
cell proliferation GO:0008283 299 0.034
detection of chemical stimulus GO:0009593 93 0.034
cell growth GO:0016049 108 0.034
terminal branching open tracheal system GO:0007430 17 0.034
branching involved in open tracheal system development GO:0060446 45 0.033
activation of cysteine type endopeptidase activity GO:0097202 17 0.033
negative regulation of synapse assembly GO:0051964 39 0.033
regulation of endocytosis GO:0030100 37 0.033
dna integrity checkpoint GO:0031570 81 0.033
amine metabolic process GO:0009308 12 0.032
protein targeting GO:0006605 64 0.032
regulation of cell cycle phase transition GO:1901987 130 0.032
nucleoside phosphate metabolic process GO:0006753 162 0.032
regulation of mitotic cell cycle GO:0007346 190 0.032
chromatin silencing GO:0006342 76 0.032
transmembrane transport GO:0055085 139 0.032
brain development GO:0007420 120 0.032
germarium derived female germ line cyst formation GO:0030727 42 0.031
histolysis GO:0007559 102 0.031
regulation of protein depolymerization GO:1901879 27 0.031
chaeta development GO:0022416 97 0.031
lipid homeostasis GO:0055088 33 0.031
Human Mouse Worm
intracellular mrna localization GO:0008298 66 0.030
negative regulation of cellular component organization GO:0051129 108 0.030
aromatic compound catabolic process GO:0019439 166 0.030
mitochondrial fission GO:0000266 8 0.030
cellular component assembly involved in morphogenesis GO:0010927 151 0.030
urogenital system development GO:0001655 72 0.030
response to nutrient levels GO:0031667 114 0.029
Mouse
regulation of cytoskeleton organization GO:0051493 89 0.029
cell recognition GO:0008037 102 0.029
regulation of mitotic cell cycle phase transition GO:1901990 130 0.029
nucleus localization GO:0051647 34 0.029
cellular lipid metabolic process GO:0044255 83 0.029
protein import into nucleus GO:0006606 51 0.029
cardiovascular system development GO:0072358 82 0.028
regulation of vesicle mediated transport GO:0060627 59 0.028
localization of cell GO:0051674 257 0.028
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.028
regulation of cell cycle process GO:0010564 181 0.028
regulation of hydrolase activity GO:0051336 97 0.028
regulation of cytoplasmic transport GO:1903649 47 0.027
cellular amino acid metabolic process GO:0006520 61 0.027
protein secretion GO:0009306 45 0.027
maintenance of protein location GO:0045185 28 0.027
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.027
regulation of hemocyte proliferation GO:0035206 37 0.027
nucleotide metabolic process GO:0009117 161 0.027
eye morphogenesis GO:0048592 260 0.027
post embryonic appendage morphogenesis GO:0035120 385 0.027
maintenance of protein location in cell GO:0032507 26 0.027
positive regulation of macromolecule metabolic process GO:0010604 405 0.026
camera type eye development GO:0043010 4 0.026
purine nucleoside catabolic process GO:0006152 112 0.026
neuron maturation GO:0042551 31 0.026
calcium ion transport GO:0006816 24 0.026
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.026
regulation of establishment of protein localization GO:0070201 61 0.026
negative regulation of cell cycle process GO:0010948 109 0.026
response to bacterium GO:0009617 198 0.026
posttranscriptional regulation of gene expression GO:0010608 145 0.026
response to organic substance GO:0010033 284 0.025
Mouse
gland development GO:0048732 191 0.025
regulation of intracellular protein transport GO:0033157 46 0.025
negative regulation of developmental process GO:0051093 201 0.025
positive regulation of cellular component biogenesis GO:0044089 80 0.025
protein phosphorylation GO:0006468 169 0.024
intracellular signal transduction GO:0035556 300 0.024
synaptic growth at neuromuscular junction GO:0051124 119 0.024
regulation of embryonic development GO:0045995 68 0.024
positive regulation of apoptotic process GO:0043065 47 0.024
protein heterooligomerization GO:0051291 4 0.024
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.024
regulation of anatomical structure size GO:0090066 163 0.024
larval development GO:0002164 104 0.024
Worm
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.024
telencephalon development GO:0021537 2 0.023
epithelial tube morphogenesis GO:0060562 88 0.023
oocyte axis specification GO:0007309 108 0.023
regulation of protein complex disassembly GO:0043244 29 0.022
cognition GO:0050890 141 0.022
secretion by cell GO:0032940 101 0.022
immune system development GO:0002520 57 0.022
rhythmic behavior GO:0007622 76 0.022
phototaxis GO:0042331 21 0.021
tissue death GO:0016271 102 0.021
response to biotic stimulus GO:0009607 294 0.021
actin filament based movement GO:0030048 26 0.021
response to external biotic stimulus GO:0043207 293 0.021
endocytic recycling GO:0032456 13 0.021
negative regulation of gene expression GO:0010629 387 0.021
oocyte development GO:0048599 124 0.021
embryo development ending in birth or egg hatching GO:0009792 152 0.020
Worm
protein import GO:0017038 55 0.020
regulation of phosphorus metabolic process GO:0051174 210 0.020
purine nucleoside triphosphate catabolic process GO:0009146 108 0.020
imaginal disc derived appendage morphogenesis GO:0035114 395 0.019
detection of light stimulus GO:0009583 58 0.019
hormone biosynthetic process GO:0042446 20 0.019
organonitrogen compound catabolic process GO:1901565 128 0.019
gastrulation GO:0007369 70 0.019
nitrogen compound transport GO:0071705 85 0.019
cellular amide metabolic process GO:0043603 80 0.019
cellular pigmentation GO:0033059 12 0.019
positive regulation of proteolysis GO:0045862 52 0.019
ribose phosphate metabolic process GO:0019693 145 0.019
ribonucleoside catabolic process GO:0042454 112 0.019
myofibril assembly GO:0030239 36 0.018
regulation of cellular catabolic process GO:0031329 157 0.018
Mouse
regulation of peptidase activity GO:0052547 39 0.018
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 4 0.018
regulation of reproductive process GO:2000241 54 0.018
Worm
chromosome organization GO:0051276 360 0.018
cellular protein complex assembly GO:0043623 71 0.018
purine containing compound catabolic process GO:0072523 112 0.018
regulation of cellular amino acid metabolic process GO:0006521 0 0.018
exocrine system development GO:0035272 162 0.018
multicellular organism growth GO:0035264 46 0.018
ribonucleoside metabolic process GO:0009119 127 0.017
regulation of cellular ketone metabolic process GO:0010565 3 0.017
vesicle mediated transport GO:0016192 381 0.017
Mouse
developmental programmed cell death GO:0010623 138 0.017
ribonucleotide catabolic process GO:0009261 109 0.017
regulation of protein import into nucleus GO:0042306 28 0.017
gtp catabolic process GO:0006184 72 0.017
positive regulation of phosphate metabolic process GO:0045937 139 0.017
regulation of actin filament length GO:0030832 27 0.017
microtubule depolymerization GO:0007019 25 0.017
mitotic spindle organization GO:0007052 220 0.017
carboxylic acid metabolic process GO:0019752 92 0.017
Mouse
oxoacid metabolic process GO:0043436 103 0.017
Mouse
response to decreased oxygen levels GO:0036293 58 0.016
developmental pigmentation GO:0048066 68 0.016
steroid catabolic process GO:0006706 1 0.016
regulation of cell adhesion GO:0030155 27 0.016
regulation of circadian sleep wake cycle GO:0042749 25 0.016
salivary gland cell autophagic cell death GO:0035071 83 0.016
chromatin organization GO:0006325 207 0.016
regulation of mitochondrial fission GO:0090140 7 0.016
sarcomere organization GO:0045214 26 0.016
divalent inorganic cation homeostasis GO:0072507 29 0.016
ribonucleoside triphosphate metabolic process GO:0009199 119 0.016
morphogenesis of a branching structure GO:0001763 45 0.016
molting cycle chitin based cuticle GO:0007591 56 0.015
tripartite regional subdivision GO:0007351 103 0.015
syncytium formation GO:0006949 43 0.015
cell cell signaling involved in cell fate commitment GO:0045168 210 0.015
regulation of cellular amine metabolic process GO:0033238 3 0.015
purine ribonucleotide metabolic process GO:0009150 145 0.015
immune effector process GO:0002252 98 0.015
morphogenesis of embryonic epithelium GO:0016331 94 0.015
transition metal ion homeostasis GO:0055076 17 0.015
columnar cuboidal epithelial cell development GO:0002066 249 0.014
positive regulation of organelle organization GO:0010638 65 0.014
positive regulation of phosphorus metabolic process GO:0010562 139 0.014
hemopoiesis GO:0030097 46 0.014
regulation of body fluid levels GO:0050878 14 0.014
hatching GO:0035188 4 0.014
regulation of translation GO:0006417 56 0.014
hormone metabolic process GO:0042445 33 0.014
regulation of synaptic transmission GO:0050804 69 0.014
regulation of ion transport GO:0043269 39 0.014
positive regulation of multicellular organismal process GO:0051240 143 0.014
positive regulation of transport GO:0051050 92 0.013
embryonic axis specification GO:0000578 107 0.013
monovalent inorganic cation transport GO:0015672 40 0.013
phosphorylation GO:0016310 294 0.013
guanosine containing compound metabolic process GO:1901068 74 0.013
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.013
detection of stimulus involved in sensory perception GO:0050906 92 0.013
nucleoside metabolic process GO:0009116 127 0.013
imaginal disc derived wing morphogenesis GO:0007476 337 0.013
mitotic dna integrity checkpoint GO:0044774 75 0.013
regulation of anatomical structure morphogenesis GO:0022603 242 0.013
eye pigmentation GO:0048069 43 0.013
maintenance of location in cell GO:0051651 28 0.012
nucleobase containing small molecule metabolic process GO:0055086 174 0.012
cellular macromolecule catabolic process GO:0044265 136 0.012
neuron death GO:0070997 27 0.012
single organism behavior GO:0044708 391 0.012
Mouse
camera type eye morphogenesis GO:0048593 2 0.012
mitochondrion organization GO:0007005 65 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.012
gene silencing GO:0016458 138 0.012
reproductive system development GO:0061458 74 0.012
connective tissue development GO:0061448 3 0.012
anterior posterior pattern specification GO:0009952 136 0.012
regulation of chromosome organization GO:0033044 64 0.012
response to inorganic substance GO:0010035 44 0.012
establishment of nucleus localization GO:0040023 26 0.012
negative regulation of programmed cell death GO:0043069 72 0.012
negative regulation of cell cycle GO:0045786 116 0.012
cgmp biosynthetic process GO:0006182 8 0.012
imaginal disc pattern formation GO:0007447 91 0.012
peptide metabolic process GO:0006518 80 0.012
actin filament polymerization GO:0030041 27 0.012
muscle attachment GO:0016203 36 0.012
negative regulation of neurogenesis GO:0050768 53 0.012
single organismal cell cell adhesion GO:0016337 45 0.012
cellular nitrogen compound catabolic process GO:0044270 165 0.012
regulation of catabolic process GO:0009894 170 0.012
Mouse
negative regulation of cell death GO:0060548 81 0.011
cell fate determination GO:0001709 91 0.011
regulation of neurogenesis GO:0050767 158 0.011
negative regulation of cellular protein metabolic process GO:0032269 85 0.011
cellular response to nutrient levels GO:0031669 62 0.011
Mouse
positive regulation of developmental process GO:0051094 143 0.011
rna localization GO:0006403 115 0.011
circadian behavior GO:0048512 76 0.011
autophagic cell death GO:0048102 83 0.011
wing disc morphogenesis GO:0007472 344 0.011
synapse assembly GO:0007416 143 0.011
regulation of mitotic sister chromatid separation GO:0010965 28 0.011
substrate adhesion dependent cell spreading GO:0034446 2 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.011
response to hexose GO:0009746 3 0.011
tissue homeostasis GO:0001894 36 0.011
protein modification by small protein removal GO:0070646 28 0.011
positive regulation of intracellular signal transduction GO:1902533 116 0.011
phagocytosis GO:0006909 215 0.011
salivary gland development GO:0007431 162 0.011
dna packaging GO:0006323 91 0.011
cellular monovalent inorganic cation homeostasis GO:0030004 7 0.011
cellular response to oxygen containing compound GO:1901701 79 0.011
regulation of cell matrix adhesion GO:0001952 1 0.011
phosphatidylinositol mediated signaling GO:0048015 4 0.011
nucleobase containing compound catabolic process GO:0034655 165 0.011
nucleocytoplasmic transport GO:0006913 72 0.011
nucleoside catabolic process GO:0009164 112 0.010
positive regulation of cellular biosynthetic process GO:0031328 316 0.010
gland morphogenesis GO:0022612 145 0.010
negative regulation of gene expression epigenetic GO:0045814 77 0.010
rhythmic process GO:0048511 106 0.010
sensory organ morphogenesis GO:0090596 260 0.010
salivary gland morphogenesis GO:0007435 145 0.010

Npc1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.034
Human
cancer DOID:162 0 0.028
disease of cellular proliferation DOID:14566 0 0.028
nervous system disease DOID:863 0 0.019
organ system cancer DOID:0050686 0 0.018
disease of metabolism DOID:0014667 0 0.016
Human
inherited metabolic disorder DOID:655 0 0.016
Human