Drosophila melanogaster

156 known processes

Dref (Dmel_CG5838)

DNA replication-related element factor

(Aliases: CG5838,p80,p80/DREF,dref,DmDREF,dDREF,Dmel_DREF,Dmel\CG5838,DREF)

Dref biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chromosome organization GO:0051276 360 1.000
chromatin organization GO:0006325 207 0.994
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.984
chromatin modification GO:0016568 147 0.982
negative regulation of cell cycle process GO:0010948 109 0.963
dna replication GO:0006260 48 0.953
programmed cell death GO:0012501 257 0.945
cell cycle phase transition GO:0044770 140 0.944
regulation of chromosome organization GO:0033044 64 0.942
meiotic cell cycle process GO:1903046 132 0.919
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.901
negative regulation of rna biosynthetic process GO:1902679 240 0.894
dendrite morphogenesis GO:0048813 199 0.887
dendrite development GO:0016358 204 0.874
covalent chromatin modification GO:0016569 106 0.860
mitotic cell cycle checkpoint GO:0007093 88 0.858
meiotic cell cycle GO:0051321 171 0.857
negative regulation of cellular metabolic process GO:0031324 382 0.853
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.847
mitotic cell cycle phase transition GO:0044772 138 0.842
organelle fission GO:0048285 340 0.799
cell cycle checkpoint GO:0000075 95 0.772
regulation of cell cycle process GO:0010564 181 0.763
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.751
dna metabolic process GO:0006259 227 0.738
nuclear division GO:0000280 332 0.719
mitotic dna damage checkpoint GO:0044773 74 0.719
regulation of chromatin organization GO:1902275 32 0.715
negative regulation of nucleic acid templated transcription GO:1903507 240 0.705
positive regulation of transcription dna templated GO:0045893 266 0.701
histone modification GO:0016570 106 0.698
regulation of mitotic cell cycle phase transition GO:1901990 130 0.697
positive regulation of macromolecule metabolic process GO:0010604 405 0.675
negative regulation of cell cycle phase transition GO:1901988 103 0.627
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.623
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.621
negative regulation of transcription dna templated GO:0045892 237 0.603
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.587
cellular protein modification process GO:0006464 438 0.569
gliogenesis GO:0042063 80 0.550
immune system process GO:0002376 347 0.522
lipid metabolic process GO:0006629 121 0.512
negative regulation of catabolic process GO:0009895 36 0.506
transcription from rna polymerase ii promoter GO:0006366 368 0.505
regulation of cell death GO:0010941 173 0.499
tissue morphogenesis GO:0048729 297 0.498
mitotic sister chromatid segregation GO:0000070 87 0.492
mitotic sister chromatid separation GO:0051306 30 0.483
catabolic process GO:0009056 409 0.476
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.462
tissue death GO:0016271 102 0.457
sister chromatid segregation GO:0000819 92 0.453
regulation of multicellular organismal development GO:2000026 414 0.452
negative regulation of mitotic cell cycle GO:0045930 109 0.451
dna packaging GO:0006323 91 0.447
organophosphate metabolic process GO:0019637 195 0.444
metaphase anaphase transition of mitotic cell cycle GO:0007091 28 0.438
regulation of cell cycle phase transition GO:1901987 130 0.434
regulation of mitotic cell cycle GO:0007346 190 0.430
mitotic dna integrity checkpoint GO:0044774 75 0.424
cell division GO:0051301 248 0.416
cellular amino acid metabolic process GO:0006520 61 0.408
negative regulation of gene expression GO:0010629 387 0.406
regulation of cellular catabolic process GO:0031329 157 0.397
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.395
regulation of organelle organization GO:0033043 196 0.392
protein modification process GO:0036211 438 0.372
positive regulation of biosynthetic process GO:0009891 316 0.369
regulation of cell cycle GO:0051726 291 0.362
regulation of neurogenesis GO:0050767 158 0.359
regulation of cellular amino acid metabolic process GO:0006521 0 0.354
regulation of mitosis GO:0007088 56 0.353
negative regulation of biosynthetic process GO:0009890 277 0.352
defense response GO:0006952 300 0.348
actin cytoskeleton organization GO:0030036 206 0.344
positive regulation of cellular biosynthetic process GO:0031328 316 0.339
negative regulation of developmental process GO:0051093 201 0.339
chromosome segregation GO:0007059 157 0.336
organonitrogen compound metabolic process GO:1901564 318 0.329
ovarian follicle cell development GO:0030707 248 0.328
sex differentiation GO:0007548 81 0.320
negative regulation of neuroblast proliferation GO:0007406 27 0.319
positive regulation of histone deacetylation GO:0031065 2 0.317
internal peptidyl lysine acetylation GO:0018393 38 0.317
dna conformation change GO:0071103 105 0.312
modification dependent protein catabolic process GO:0019941 78 0.291
single organism biosynthetic process GO:0044711 206 0.290
dna integrity checkpoint GO:0031570 81 0.280
negative regulation of cellular biosynthetic process GO:0031327 277 0.270
glial cell migration GO:0008347 31 0.270
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 11 0.261
regulation of sister chromatid segregation GO:0033045 28 0.260
regulation of catabolic process GO:0009894 170 0.256
regulation of cell differentiation GO:0045595 302 0.253
meiotic nuclear division GO:0007126 151 0.251
negative regulation of cell cycle GO:0045786 116 0.250
regulation of mitotic sister chromatid separation GO:0010965 28 0.249
positive regulation of signal transduction GO:0009967 223 0.228
eggshell formation GO:0030703 105 0.222
regulation of chromosome segregation GO:0051983 32 0.221
brain development GO:0007420 120 0.216
maintenance of location GO:0051235 73 0.215
morphogenesis of an epithelium GO:0002009 276 0.215
actin filament based process GO:0030029 220 0.212
cell proliferation GO:0008283 299 0.208
epithelial cell differentiation GO:0030855 322 0.207
gonad development GO:0008406 50 0.202
tube morphogenesis GO:0035239 191 0.196
chorion containing eggshell formation GO:0007304 105 0.194
positive regulation of nucleic acid templated transcription GO:1903508 266 0.190
response to biotic stimulus GO:0009607 294 0.188
cellular response to dna damage stimulus GO:0006974 223 0.183
asymmetric stem cell division GO:0098722 49 0.178
developmental programmed cell death GO:0010623 138 0.176
positive regulation of cell communication GO:0010647 250 0.173
regulation of chromatin modification GO:1903308 28 0.166
regulation of cellular amine metabolic process GO:0033238 3 0.165
response to radiation GO:0009314 155 0.165
genitalia development GO:0048806 26 0.164
photoreceptor cell differentiation GO:0046530 170 0.162
epithelial cell development GO:0002064 274 0.161
intracellular signal transduction GO:0035556 300 0.158
peptidyl lysine acetylation GO:0018394 39 0.146
gene silencing GO:0016458 138 0.145
eye photoreceptor cell differentiation GO:0001754 145 0.144
spermatogenesis GO:0007283 200 0.142
protein dna complex assembly GO:0065004 63 0.140
regionalization GO:0003002 416 0.139
gland morphogenesis GO:0022612 145 0.139
phagocytosis GO:0006909 215 0.135
regulation of cellular ketone metabolic process GO:0010565 3 0.134
negative regulation of gene expression epigenetic GO:0045814 77 0.131
metaphase anaphase transition of cell cycle GO:0044784 28 0.130
developmental growth GO:0048589 280 0.130
single organism catabolic process GO:0044712 228 0.128
ribonucleoside catabolic process GO:0042454 112 0.128
macromolecule catabolic process GO:0009057 161 0.127
regulation of molecular function GO:0065009 217 0.122
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.121
epithelial tube morphogenesis GO:0060562 88 0.121
positive regulation of catabolic process GO:0009896 105 0.120
death GO:0016265 284 0.120
cellular catabolic process GO:0044248 372 0.120
macromolecular complex assembly GO:0065003 256 0.120
development of primary sexual characteristics GO:0045137 50 0.119
cell cycle dna replication GO:0044786 23 0.117
positive regulation of protein metabolic process GO:0051247 128 0.115
immune response GO:0006955 246 0.115
regulation of histone modification GO:0031056 20 0.112
growth GO:0040007 359 0.111
regulation of programmed cell death GO:0043067 152 0.111
carbohydrate derivative catabolic process GO:1901136 118 0.111
positive regulation of proteolysis GO:0045862 52 0.107
cellular protein catabolic process GO:0044257 83 0.105
small molecule metabolic process GO:0044281 305 0.104
positive regulation of signaling GO:0023056 243 0.103
regulation of phosphate metabolic process GO:0019220 210 0.103
embryo development ending in birth or egg hatching GO:0009792 152 0.100
negative regulation of cellular catabolic process GO:0031330 34 0.100
negative regulation of cell death GO:0060548 81 0.099
positive regulation of rna metabolic process GO:0051254 271 0.099
nucleoside triphosphate catabolic process GO:0009143 108 0.097
cellular response to oxygen containing compound GO:1901701 79 0.096
positive regulation of photoreceptor cell differentiation GO:0046534 12 0.096
phosphorylation GO:0016310 294 0.095
regulation of dna metabolic process GO:0051052 34 0.094
negative regulation of catalytic activity GO:0043086 42 0.093
chemosensory behavior GO:0007635 106 0.093
cell motility GO:0048870 251 0.092
mitotic spindle organization GO:0007052 220 0.092
cellular amine metabolic process GO:0044106 12 0.090
nucleotide metabolic process GO:0009117 161 0.088
male gamete generation GO:0048232 201 0.086
dna damage checkpoint GO:0000077 78 0.086
glycosyl compound catabolic process GO:1901658 112 0.085
positive regulation of response to stimulus GO:0048584 323 0.085
compound eye photoreceptor development GO:0042051 78 0.085
compound eye photoreceptor cell differentiation GO:0001751 140 0.084
response to other organism GO:0051707 293 0.083
negative regulation of rna metabolic process GO:0051253 251 0.083
regulation of neuron differentiation GO:0045664 103 0.082
proteasomal protein catabolic process GO:0010498 59 0.081
organic acid metabolic process GO:0006082 103 0.080
negative regulation of mitotic anaphase promoting complex activity GO:0060564 2 0.080
regulation of histone deacetylation GO:0031063 2 0.078
organic cyclic compound catabolic process GO:1901361 168 0.078
chromatin assembly GO:0031497 48 0.078
cell type specific apoptotic process GO:0097285 38 0.077
protein localization GO:0008104 284 0.077
regulation of cellular protein metabolic process GO:0032268 243 0.076
aromatic compound catabolic process GO:0019439 166 0.076
regulation of phosphorus metabolic process GO:0051174 210 0.076
nucleoside phosphate metabolic process GO:0006753 162 0.076
eye development GO:0001654 323 0.076
regulation of organ growth GO:0046620 42 0.075
regulation of intracellular signal transduction GO:1902531 236 0.074
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.074
regulation of apoptotic process GO:0042981 130 0.072
regulation of proteolysis GO:0030162 87 0.071
response to external biotic stimulus GO:0043207 293 0.069
purine containing compound catabolic process GO:0072523 112 0.069
negative regulation of phosphate metabolic process GO:0045936 45 0.069
positive regulation of gene expression GO:0010628 290 0.067
meiotic chromosome segregation GO:0045132 59 0.067
chromatin silencing GO:0006342 76 0.067
protein localization to nucleus GO:0034504 55 0.067
regulation of binding GO:0051098 16 0.067
ribonucleoside metabolic process GO:0009119 127 0.067
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.066
negative regulation of response to stimulus GO:0048585 258 0.065
positive regulation of protein deacetylation GO:0090312 2 0.064
response to organic substance GO:0010033 284 0.063
oocyte maturation GO:0001556 3 0.063
positive regulation of rna biosynthetic process GO:1902680 266 0.063
peptidyl amino acid modification GO:0018193 105 0.063
wnt signaling pathway GO:0016055 98 0.062
salivary gland morphogenesis GO:0007435 145 0.062
g2 dna damage checkpoint GO:0031572 69 0.061
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.060
regulation of cell division GO:0051302 72 0.060
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.060
intrinsic apoptotic signaling pathway GO:0097193 16 0.060
oxoacid metabolic process GO:0043436 103 0.059
ubiquitin dependent protein catabolic process GO:0006511 78 0.058
ribose phosphate metabolic process GO:0019693 145 0.058
neuron remodeling GO:0016322 29 0.058
chromatin assembly or disassembly GO:0006333 52 0.057
response to abiotic stimulus GO:0009628 341 0.057
nucleus organization GO:0006997 45 0.056
carbohydrate derivative metabolic process GO:1901135 217 0.056
regulation of protein catabolic process GO:0042176 55 0.056
regulation of mitotic sister chromatid segregation GO:0033047 28 0.056
cellular nitrogen compound catabolic process GO:0044270 165 0.055
apoptotic process GO:0006915 159 0.054
regulation of cellular protein catabolic process GO:1903362 44 0.054
male meiosis GO:0007140 52 0.054
small gtpase mediated signal transduction GO:0007264 88 0.053
purine nucleoside triphosphate catabolic process GO:0009146 108 0.053
regulation of anatomical structure morphogenesis GO:0022603 242 0.053
chromosome separation GO:0051304 42 0.053
eye morphogenesis GO:0048592 260 0.052
organonitrogen compound biosynthetic process GO:1901566 117 0.052
positive regulation of multicellular organismal process GO:0051240 143 0.052
chromatin remodeling GO:0006338 72 0.052
protein modification by small protein conjugation or removal GO:0070647 106 0.050
nucleoside catabolic process GO:0009164 112 0.050
protein complex assembly GO:0006461 200 0.048
purine containing compound metabolic process GO:0072521 155 0.047
maintenance of protein location in cell GO:0032507 26 0.047
regulation of protein modification process GO:0031399 112 0.047
photoreceptor cell development GO:0042461 96 0.047
gland development GO:0048732 191 0.047
stem cell differentiation GO:0048863 117 0.047
spindle organization GO:0007051 253 0.047
cardiovascular system development GO:0072358 82 0.047
positive regulation of cell proliferation GO:0008284 47 0.047
social behavior GO:0035176 4 0.047
histolysis GO:0007559 102 0.047
endocytosis GO:0006897 310 0.047
protein processing GO:0016485 68 0.046
head development GO:0060322 135 0.044
positive regulation of nucleotide metabolic process GO:0045981 55 0.044
glial cell fate determination GO:0007403 3 0.044
amine metabolic process GO:0009308 12 0.044
salivary gland histolysis GO:0035070 88 0.044
positive regulation of r7 cell differentiation GO:0045678 7 0.043
negative regulation of mitotic sister chromatid separation GO:2000816 13 0.043
negative regulation of stem cell proliferation GO:2000647 30 0.043
negative regulation of programmed cell death GO:0043069 72 0.043
regulation of protein transport GO:0051223 57 0.043
regulation of peptidyl lysine acetylation GO:2000756 7 0.042
proteolysis GO:0006508 192 0.041
stem cell division GO:0017145 69 0.041
regulation of cell morphogenesis GO:0022604 163 0.040
exocrine system development GO:0035272 162 0.040
positive regulation of phosphate metabolic process GO:0045937 139 0.040
regulation of hemocyte proliferation GO:0035206 37 0.040
eye photoreceptor cell development GO:0042462 81 0.039
negative regulation of chromosome segregation GO:0051985 14 0.039
ribonucleotide catabolic process GO:0009261 109 0.038
salivary gland development GO:0007431 162 0.038
defense response to bacterium GO:0042742 178 0.038
stem cell maintenance GO:0019827 67 0.038
ion transport GO:0006811 145 0.038
regulation of nucleotide catabolic process GO:0030811 48 0.037
purine nucleoside metabolic process GO:0042278 127 0.037
protein modification by small protein conjugation GO:0032446 79 0.037
central nervous system development GO:0007417 201 0.037
negative regulation of meiotic cell cycle GO:0051447 2 0.036
neuron maturation GO:0042551 31 0.036
appendage development GO:0048736 401 0.036
hemopoiesis GO:0030097 46 0.036
imaginal disc derived appendage development GO:0048737 399 0.035
intracellular receptor signaling pathway GO:0030522 19 0.035
negative regulation of cellular component organization GO:0051129 108 0.035
regulation of antibacterial peptide production GO:0002786 22 0.035
ribonucleoside triphosphate metabolic process GO:0009199 119 0.035
organonitrogen compound catabolic process GO:1901565 128 0.035
positive regulation of cell death GO:0010942 69 0.034
cellular response to chemical stimulus GO:0070887 199 0.034
regulation of protein processing GO:0070613 32 0.034
regulation of nuclear division GO:0051783 58 0.034
cellular amide metabolic process GO:0043603 80 0.034
regulation of cell development GO:0060284 215 0.034
autophagic cell death GO:0048102 83 0.033
columnar cuboidal epithelial cell development GO:0002066 249 0.033
notch signaling pathway GO:0007219 120 0.032
positive regulation of chromosome segregation GO:0051984 10 0.032
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.031
single organism behavior GO:0044708 391 0.031
regulation of protein deacetylation GO:0090311 2 0.031
regulation of histone acetylation GO:0035065 7 0.031
positive regulation of neurogenesis GO:0050769 41 0.031
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.031
muscle organ development GO:0007517 127 0.031
reproductive system development GO:0061458 74 0.031
branching morphogenesis of an epithelial tube GO:0048754 45 0.031
positive regulation of phosphorus metabolic process GO:0010562 139 0.030
respiratory system development GO:0060541 213 0.030
purine nucleotide metabolic process GO:0006163 146 0.030
negative regulation of mitotic metaphase anaphase transition GO:0045841 13 0.030
maintenance of location in cell GO:0051651 28 0.030
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.029
regulation of cellular component biogenesis GO:0044087 201 0.029
germarium derived egg chamber formation GO:0007293 101 0.029
regulation of trichome morphogenesis GO:2000039 3 0.029
positive regulation of cellular protein metabolic process GO:0032270 118 0.029
embryonic development via the syncytial blastoderm GO:0001700 148 0.028
negative regulation of cell differentiation GO:0045596 143 0.028
axonogenesis GO:0007409 290 0.028
regulation of g1 s transition of mitotic cell cycle GO:2000045 23 0.028
negative regulation of meiotic cell cycle phase transition GO:1901994 1 0.028
negative regulation of neurogenesis GO:0050768 53 0.028
eggshell chorion assembly GO:0007306 66 0.028
regulation of cytoskeleton organization GO:0051493 89 0.028
nucleotide catabolic process GO:0009166 109 0.028
regulation of developmental growth GO:0048638 174 0.027
protein complex biogenesis GO:0070271 201 0.027
cellular ketone metabolic process GO:0042180 24 0.027
protein catabolic process GO:0030163 101 0.027
cell proliferation involved in compound eye morphogenesis GO:0035736 4 0.027
positive regulation of mitotic sister chromatid separation GO:1901970 10 0.027
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.027
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.027
p granule organization GO:0030719 4 0.027
compound eye development GO:0048749 307 0.026
pole cell migration GO:0007280 13 0.026
chaeta development GO:0022416 97 0.026
regulation of response to stress GO:0080134 200 0.026
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.026
regulation of cell cycle g1 s phase transition GO:1902806 23 0.026
regulation of innate immune response GO:0045088 71 0.026
axon development GO:0061564 297 0.025
regulation of kinase activity GO:0043549 53 0.025
protein phosphorylation GO:0006468 169 0.024
regulation of catalytic activity GO:0050790 185 0.024
organ growth GO:0035265 56 0.024
positive regulation of protein modification process GO:0031401 58 0.024
cell fate determination GO:0001709 91 0.024
positive regulation of organelle organization GO:0010638 65 0.024
sensory organ precursor cell division GO:0045035 10 0.024
negative regulation of intracellular signal transduction GO:1902532 57 0.023
regulation of intracellular protein transport GO:0033157 46 0.023
neuroblast proliferation GO:0007405 74 0.023
dendrite regeneration GO:0031104 2 0.022
oocyte morphogenesis GO:0048601 3 0.022
positive regulation of cell differentiation GO:0045597 64 0.022
protein localization to organelle GO:0033365 82 0.022
regulation of transport GO:0051049 181 0.022
defense response to other organism GO:0098542 225 0.022
nitrogen compound transport GO:0071705 85 0.022
organic substance transport GO:0071702 257 0.022
negative regulation of neural precursor cell proliferation GO:2000178 27 0.022
regulation of gtp catabolic process GO:0033124 44 0.022
maternal determination of dorsal ventral axis ovarian follicular epithelium soma encoded GO:0008071 1 0.022
purine ribonucleotide metabolic process GO:0009150 145 0.021
regulation of cell proliferation involved in compound eye morphogenesis GO:2000495 2 0.021
regulation of nervous system development GO:0051960 248 0.021
negative regulation of organelle organization GO:0010639 56 0.021
purine nucleoside catabolic process GO:0006152 112 0.021
germ line stem cell maintenance GO:0030718 50 0.021
innate immune response GO:0045087 144 0.021
cellular macromolecular complex assembly GO:0034622 153 0.021
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 24 0.021
negative regulation of terminal cell fate specification open tracheal system GO:0035155 2 0.021
regulation of protein kinase activity GO:0045859 51 0.020
cell death GO:0008219 279 0.020
purine nucleoside triphosphate metabolic process GO:0009144 119 0.020
positive regulation of immune system process GO:0002684 68 0.020
regulation of protein metabolic process GO:0051246 256 0.020
antimicrobial humoral response GO:0019730 99 0.020
imaginal disc derived wing vein specification GO:0007474 48 0.020
regulation of cytoplasmic transport GO:1903649 47 0.020
regulation of glial cell proliferation GO:0060251 11 0.020
head involution GO:0008258 35 0.020
salivary gland cell autophagic cell death GO:0035071 83 0.020
histone deacetylation GO:0016575 9 0.020
positive regulation of nucleoside metabolic process GO:0045979 47 0.020
nucleoside triphosphate metabolic process GO:0009141 120 0.020
ras protein signal transduction GO:0007265 88 0.019
positive regulation of gliogenesis GO:0014015 5 0.019
regulation of calcium ion transmembrane transport GO:1903169 2 0.019
positive regulation of intracellular signal transduction GO:1902533 116 0.019
response to oxygen containing compound GO:1901700 200 0.019
regulation of planar cell polarity pathway involved in axis elongation GO:2000040 2 0.018
regulation of organ morphogenesis GO:2000027 78 0.018
tube development GO:0035295 244 0.018
negative regulation of apoptotic process GO:0043066 63 0.018
wing disc morphogenesis GO:0007472 344 0.018
nucleobase containing small molecule metabolic process GO:0055086 174 0.018
heterocycle catabolic process GO:0046700 166 0.018
positive regulation of cellular amine metabolic process GO:0033240 0 0.018
regulation of epithelial cell proliferation GO:0050678 4 0.017
forebrain development GO:0030900 2 0.017
cellular response to amino acid starvation GO:0034198 7 0.017
olfactory behavior GO:0042048 97 0.017
positive regulation of mitotic metaphase anaphase transition GO:0045842 10 0.017
regulation of nucleotide metabolic process GO:0006140 62 0.017
signal transduction in response to dna damage GO:0042770 3 0.017
ribonucleotide metabolic process GO:0009259 145 0.017
single organism carbohydrate metabolic process GO:0044723 72 0.017
regulation of striated muscle contraction GO:0006942 2 0.017
regulation of immune response GO:0050776 118 0.017
negative regulation of protein processing GO:0010955 31 0.017
positive regulation of apoptotic signaling pathway GO:2001235 4 0.016
regulation of dna replication GO:0006275 13 0.016
carbohydrate metabolic process GO:0005975 82 0.016
nucleoside metabolic process GO:0009116 127 0.016
regulation of cell proliferation GO:0042127 163 0.016
regulation of notch signaling pathway GO:0008593 100 0.016
imaginal disc derived wing morphogenesis GO:0007476 337 0.016
regulation of ras protein signal transduction GO:0046578 93 0.016
imaginal disc derived leg morphogenesis GO:0007480 80 0.016
limb development GO:0060173 1 0.016
negative regulation of protein maturation GO:1903318 31 0.016
mapk cascade GO:0000165 107 0.016
carboxylic acid metabolic process GO:0019752 92 0.016
response to uv GO:0009411 24 0.015
protein acetylation GO:0006473 39 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.015
positive regulation of molecular function GO:0044093 136 0.015
positive regulation of cell morphogenesis involved in differentiation GO:0010770 12 0.015
cell cycle g1 s phase transition GO:0044843 31 0.015
regulation of proteasomal protein catabolic process GO:0061136 39 0.014
neuron projection guidance GO:0097485 241 0.014
positive regulation of synaptic vesicle exocytosis GO:2000302 1 0.014
regulation of neuron projection development GO:0010975 69 0.014
histone methylation GO:0016571 40 0.014
mitotic nuclear division GO:0007067 213 0.014
regulation of intracellular transport GO:0032386 64 0.014
regulation of hydrolase activity GO:0051336 97 0.014
regulation of transferase activity GO:0051338 58 0.014
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 30 0.014
rhythmic process GO:0048511 106 0.014
negative regulation of cell communication GO:0010648 223 0.014
protein transport GO:0015031 155 0.014
modification dependent macromolecule catabolic process GO:0043632 79 0.014
cellular response to organic substance GO:0071310 132 0.014
positive regulation of metaphase anaphase transition of cell cycle GO:1902101 10 0.013
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 17 0.013
stem cell development GO:0048864 79 0.013
negative regulation of chromosome organization GO:2001251 19 0.013
body morphogenesis GO:0010171 2 0.013
reactive oxygen species biosynthetic process GO:1903409 0 0.013
purine ribonucleotide catabolic process GO:0009154 109 0.013
regulation of phosphorylation GO:0042325 147 0.013
meiotic spindle checkpoint GO:0044779 1 0.013
embryonic organ development GO:0048568 50 0.013
r3 r4 cell fate commitment GO:0007464 10 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.013
regulation of reactive oxygen species biosynthetic process GO:1903426 0 0.013
membrane invagination GO:0010324 11 0.013
cell cell signaling involved in cell fate commitment GO:0045168 210 0.012
dorsal closure leading edge cell differentiation GO:0046663 2 0.012
negative regulation of metaphase anaphase transition of cell cycle GO:1902100 13 0.012
organic substance catabolic process GO:1901575 308 0.012
positive regulation of hydrolase activity GO:0051345 78 0.012

Dref disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
brachydactyly DOID:0050581 0 0.043
bone development disease DOID:0080006 0 0.043
bone disease DOID:0080001 0 0.043
disease of anatomical entity DOID:7 0 0.043
dysostosis DOID:1934 0 0.043
musculoskeletal system disease DOID:17 0 0.043
connective tissue disease DOID:65 0 0.043
artery disease DOID:0050828 0 0.021
aortic aneurysm DOID:3627 0 0.021
vascular disease DOID:178 0 0.021
cardiovascular system disease DOID:1287 0 0.021
aortic disease DOID:520 0 0.021
pancreatic carcinoma DOID:4905 0 0.012
endocrine gland cancer DOID:170 0 0.012
cancer DOID:162 0 0.012
pancreatic cancer DOID:1793 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
organ system cancer DOID:0050686 0 0.012