Drosophila melanogaster

73 known processes

NELF-A (Dmel_CG5874)

CG5874 gene product from transcript CG5874-RA

(Aliases: NELF,CG5874,BcDNA:SD07139,Dmel\CG5874,Nelf-A)

NELF-A biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.570
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.538
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.408
negative regulation of rna biosynthetic process GO:1902679 240 0.366
positive regulation of rna metabolic process GO:0051254 271 0.363
regulation of small gtpase mediated signal transduction GO:0051056 93 0.317
positive regulation of cellular biosynthetic process GO:0031328 316 0.304
cell motility GO:0048870 251 0.295
organonitrogen compound metabolic process GO:1901564 318 0.285
intracellular signal transduction GO:0035556 300 0.257
positive regulation of rna biosynthetic process GO:1902680 266 0.256
segmentation GO:0035282 207 0.250
negative regulation of biosynthetic process GO:0009890 277 0.248
embryo development ending in birth or egg hatching GO:0009792 152 0.227
organic substance catabolic process GO:1901575 308 0.218
regulation of intracellular signal transduction GO:1902531 236 0.205
positive regulation of phosphate metabolic process GO:0045937 139 0.199
regulation of catabolic process GO:0009894 170 0.197
small molecule metabolic process GO:0044281 305 0.192
regulation of phosphate metabolic process GO:0019220 210 0.171
positive regulation of transcription dna templated GO:0045893 266 0.163
localization of cell GO:0051674 257 0.152
regulation of ras protein signal transduction GO:0046578 93 0.151
positive regulation of phosphorus metabolic process GO:0010562 139 0.140
regulation of cellular catabolic process GO:0031329 157 0.140
tissue morphogenesis GO:0048729 297 0.138
epithelial cell differentiation GO:0030855 322 0.138
regulation of molecular function GO:0065009 217 0.134
regulation of nucleoside metabolic process GO:0009118 50 0.134
ras protein signal transduction GO:0007265 88 0.122
positive regulation of gtpase activity GO:0043547 43 0.119
negative regulation of gene expression GO:0010629 387 0.116
small gtpase mediated signal transduction GO:0007264 88 0.111
regulation of cell cycle process GO:0010564 181 0.110
positive regulation of macromolecule metabolic process GO:0010604 405 0.107
death GO:0016265 284 0.106
cellular amino acid metabolic process GO:0006520 61 0.102
embryonic development via the syncytial blastoderm GO:0001700 148 0.098
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.093
positive regulation of nucleic acid templated transcription GO:1903508 266 0.092
nucleobase containing compound catabolic process GO:0034655 165 0.090
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.090
epithelial cell development GO:0002064 274 0.086
phosphorylation GO:0016310 294 0.086
positive regulation of molecular function GO:0044093 136 0.086
regionalization GO:0003002 416 0.085
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.083
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.082
posttranscriptional gene silencing GO:0016441 46 0.081
cell death GO:0008219 279 0.080
regulation of anatomical structure morphogenesis GO:0022603 242 0.080
nuclear division GO:0000280 332 0.079
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.077
regulation of cell shape GO:0008360 113 0.076
establishment of localization in cell GO:0051649 402 0.071
purine nucleotide metabolic process GO:0006163 146 0.070
regulation of catalytic activity GO:0050790 185 0.068
positive regulation of gene expression GO:0010628 290 0.067
positive regulation of biosynthetic process GO:0009891 316 0.065
cellular protein modification process GO:0006464 438 0.065
positive regulation of gtp catabolic process GO:0033126 43 0.064
negative regulation of nucleic acid templated transcription GO:1903507 240 0.063
positive regulation of cellular catabolic process GO:0031331 95 0.063
cell migration GO:0016477 238 0.062
regulation of cellular protein metabolic process GO:0032268 243 0.061
positive regulation of nucleotide metabolic process GO:0045981 55 0.060
guanosine containing compound metabolic process GO:1901068 74 0.060
negative regulation of rna metabolic process GO:0051253 251 0.058
nucleotide metabolic process GO:0009117 161 0.057
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.057
tube morphogenesis GO:0035239 191 0.056
cellular nitrogen compound catabolic process GO:0044270 165 0.055
cellular catabolic process GO:0044248 372 0.055
organelle fission GO:0048285 340 0.054
positive regulation of ras gtpase activity GO:0032320 36 0.054
regulation of hydrolase activity GO:0051336 97 0.053
developmental programmed cell death GO:0010623 138 0.053
regulation of cell fate commitment GO:0010453 29 0.052
gland development GO:0048732 191 0.051
regulation of cell morphogenesis GO:0022604 163 0.050
regulation of nucleotide metabolic process GO:0006140 62 0.050
immune system process GO:0002376 347 0.049
microtubule organizing center organization GO:0031023 168 0.047
cell adhesion GO:0007155 136 0.046
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.044
regulation of cellular amine metabolic process GO:0033238 3 0.044
mitotic g2 dna damage checkpoint GO:0007095 69 0.044
embryonic morphogenesis GO:0048598 206 0.044
immune response GO:0006955 246 0.041
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.041
ribose phosphate metabolic process GO:0019693 145 0.040
regulation of chromosome organization GO:0033044 64 0.040
meiotic cell cycle GO:0051321 171 0.040
cellular amine metabolic process GO:0044106 12 0.040
regulation of immune system process GO:0002682 176 0.040
negative regulation of cellular biosynthetic process GO:0031327 277 0.040
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.039
transcription from rna polymerase ii promoter GO:0006366 368 0.039
anterior posterior axis specification GO:0009948 109 0.038
positive regulation of catalytic activity GO:0043085 118 0.038
purine nucleoside catabolic process GO:0006152 112 0.037
positive regulation of nucleoside metabolic process GO:0045979 47 0.037
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.037
mitotic sister chromatid segregation GO:0000070 87 0.036
positive regulation of multicellular organismal process GO:0051240 143 0.035
hematopoietic progenitor cell differentiation GO:0002244 1 0.035
exocrine system development GO:0035272 162 0.035
aromatic compound catabolic process GO:0019439 166 0.035
regulation of protein metabolic process GO:0051246 256 0.034
regulation of purine nucleotide metabolic process GO:1900542 62 0.034
proteolysis GO:0006508 192 0.034
tissue death GO:0016271 102 0.034
positive regulation of catabolic process GO:0009896 105 0.034
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.033
purine ribonucleoside metabolic process GO:0046128 127 0.033
single organism catabolic process GO:0044712 228 0.032
kidney development GO:0001822 3 0.032
response to biotic stimulus GO:0009607 294 0.032
morphogenesis of embryonic epithelium GO:0016331 94 0.032
regulation of nucleotide catabolic process GO:0030811 48 0.031
histone modification GO:0016570 106 0.031
imaginal disc pattern formation GO:0007447 91 0.031
regulation of cellular ketone metabolic process GO:0010565 3 0.031
cell division GO:0051301 248 0.030
glycosyl compound catabolic process GO:1901658 112 0.030
regulation of cellular amino acid metabolic process GO:0006521 0 0.029
camera type eye morphogenesis GO:0048593 2 0.029
nucleoside phosphate metabolic process GO:0006753 162 0.028
ribonucleoside triphosphate metabolic process GO:0009199 119 0.028
regulation of phosphorylation GO:0042325 147 0.028
single organism cellular localization GO:1902580 180 0.028
protein ubiquitination GO:0016567 70 0.028
negative regulation of cell cycle phase transition GO:1901988 103 0.028
negative regulation of signal transduction GO:0009968 206 0.028
macromolecular complex assembly GO:0065003 256 0.027
regulation of phosphorus metabolic process GO:0051174 210 0.027
meiotic nuclear division GO:0007126 151 0.027
gene silencing GO:0016458 138 0.027
gtp catabolic process GO:0006184 72 0.027
positive regulation of phosphorylation GO:0042327 87 0.027
regulation of cell proliferation GO:0042127 163 0.026
vesicle mediated transport GO:0016192 381 0.026
positive regulation of cellular protein metabolic process GO:0032270 118 0.026
purine nucleoside triphosphate catabolic process GO:0009146 108 0.026
antimicrobial humoral response GO:0019730 99 0.026
regulation of gtp catabolic process GO:0033124 44 0.026
regulation of gene expression epigenetic GO:0040029 128 0.026
ribonucleotide metabolic process GO:0009259 145 0.026
cell cycle comprising mitosis without cytokinesis GO:0033301 25 0.026
regulation of localization GO:0032879 275 0.025
regulation of programmed cell death GO:0043067 152 0.025
establishment of planar polarity GO:0001736 87 0.025
purine nucleoside metabolic process GO:0042278 127 0.024
organophosphate metabolic process GO:0019637 195 0.024
positive regulation of cellular amine metabolic process GO:0033240 0 0.024
protein phosphorylation GO:0006468 169 0.024
nephron development GO:0072006 3 0.024
guanosine containing compound catabolic process GO:1901069 74 0.024
digestive system development GO:0055123 149 0.023
single organism biosynthetic process GO:0044711 206 0.023
regulation of transport GO:0051049 181 0.023
positive regulation of chromatin silencing at telomere GO:0031940 2 0.023
nucleobase containing small molecule metabolic process GO:0055086 174 0.023
cellular macromolecule localization GO:0070727 220 0.023
cellular ketone metabolic process GO:0042180 24 0.023
purine nucleoside triphosphate metabolic process GO:0009144 119 0.023
nucleoside metabolic process GO:0009116 127 0.022
regulation of protein modification process GO:0031399 112 0.022
kidney epithelium development GO:0072073 3 0.022
purine ribonucleotide metabolic process GO:0009150 145 0.022
morphogenesis of an epithelium GO:0002009 276 0.021
regulation of cell development GO:0060284 215 0.021
centrosome organization GO:0051297 163 0.021
regulation of meiosis GO:0040020 3 0.021
anterior posterior pattern specification GO:0009952 136 0.021
apoptotic process GO:0006915 159 0.021
positive regulation of intracellular signal transduction GO:1902533 116 0.021
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.021
positive regulation of hydrolase activity GO:0051345 78 0.021
purine containing compound metabolic process GO:0072521 155 0.021
development of primary sexual characteristics GO:0045137 50 0.020
negative regulation of cell communication GO:0010648 223 0.020
catabolic process GO:0009056 409 0.020
imaginal disc derived wing morphogenesis GO:0007476 337 0.020
response to organic substance GO:0010033 284 0.020
regulation of stem cell proliferation GO:0072091 40 0.020
chromatin silencing GO:0006342 76 0.020
amine metabolic process GO:0009308 12 0.020
macromolecule catabolic process GO:0009057 161 0.019
mitotic cell cycle embryonic GO:0045448 38 0.019
histolysis GO:0007559 102 0.019
organonitrogen compound biosynthetic process GO:1901566 117 0.019
blastoderm segmentation GO:0007350 159 0.019
body morphogenesis GO:0010171 2 0.019
columnar cuboidal epithelial cell development GO:0002066 249 0.019
regulation of gtpase activity GO:0043087 44 0.019
carboxylic acid metabolic process GO:0019752 92 0.019
protein modification by small protein conjugation or removal GO:0070647 106 0.019
reproductive structure development GO:0048608 74 0.019
positive regulation of protein modification process GO:0031401 58 0.019
embryonic pattern specification GO:0009880 174 0.019
mitotic nuclear division GO:0007067 213 0.019
ribonucleotide catabolic process GO:0009261 109 0.018
nucleoside catabolic process GO:0009164 112 0.018
nucleotide catabolic process GO:0009166 109 0.018
positive regulation of nucleotide catabolic process GO:0030813 46 0.018
nucleoside triphosphate metabolic process GO:0009141 120 0.018
purine containing compound catabolic process GO:0072523 112 0.018
protein complex biogenesis GO:0070271 201 0.018
organic cyclic compound catabolic process GO:1901361 168 0.018
regulation of organelle organization GO:0033043 196 0.018
regulation of purine nucleotide catabolic process GO:0033121 48 0.017
oxoacid metabolic process GO:0043436 103 0.017
regulation of cell cycle phase transition GO:1901987 130 0.017
negative regulation of cellular metabolic process GO:0031324 382 0.017
wing disc morphogenesis GO:0007472 344 0.017
glycosyl compound metabolic process GO:1901657 127 0.017
positive regulation of signal transduction GO:0009967 223 0.017
positive regulation of developmental growth GO:0048639 62 0.017
sex differentiation GO:0007548 81 0.016
epithelium migration GO:0090132 148 0.016
endomembrane system organization GO:0010256 119 0.016
formation of a compartment boundary GO:0060288 4 0.016
positive regulation of cell communication GO:0010647 250 0.016
regulation of neural precursor cell proliferation GO:2000177 35 0.016
ribonucleoside catabolic process GO:0042454 112 0.016
cellular macromolecular complex assembly GO:0034622 153 0.016
establishment or maintenance of cell polarity GO:0007163 167 0.015
cuticle development GO:0042335 86 0.015
protein catabolic process GO:0030163 101 0.015
positive regulation of signaling GO:0023056 243 0.015
positive regulation of protein metabolic process GO:0051247 128 0.015
developmental growth GO:0048589 280 0.015
positive regulation of cellular component organization GO:0051130 156 0.015
ribonucleoside metabolic process GO:0009119 127 0.015
salivary gland morphogenesis GO:0007435 145 0.015
organophosphate catabolic process GO:0046434 112 0.015
ovarian follicle cell development GO:0030707 248 0.014
innate immune response GO:0045087 144 0.014
cellular macromolecule catabolic process GO:0044265 136 0.014
morphogenesis of a polarized epithelium GO:0001738 93 0.014
negative regulation of phosphatase activity GO:0010923 3 0.014
protein complex assembly GO:0006461 200 0.014
purine nucleotide catabolic process GO:0006195 109 0.014
stem cell development GO:0048864 79 0.013
biological adhesion GO:0022610 138 0.013
response to other organism GO:0051707 293 0.013
actin filament based process GO:0030029 220 0.013
heterocycle catabolic process GO:0046700 166 0.013
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 4 0.013
protein alkylation GO:0008213 43 0.013
negative regulation of cell differentiation GO:0045596 143 0.013
response to endogenous stimulus GO:0009719 119 0.013
positive regulation of epidermal growth factor activated receptor activity GO:0045741 1 0.012
negative regulation of apoptotic process GO:0043066 63 0.012
response to abiotic stimulus GO:0009628 341 0.012
sensory organ morphogenesis GO:0090596 260 0.012
peptidyl amino acid modification GO:0018193 105 0.012
tube development GO:0035295 244 0.012
negative regulation of response to stimulus GO:0048585 258 0.012
programmed cell death GO:0012501 257 0.012
response to external biotic stimulus GO:0043207 293 0.012
dendrite morphogenesis GO:0048813 199 0.012
response to oxygen containing compound GO:1901700 200 0.012
regulation of nuclear division GO:0051783 58 0.012
photoreceptor cell differentiation GO:0046530 170 0.012
nucleoside triphosphate catabolic process GO:0009143 108 0.012
purine ribonucleotide catabolic process GO:0009154 109 0.011
ribonucleoside triphosphate catabolic process GO:0009203 108 0.011
organic acid metabolic process GO:0006082 103 0.011
digestive tract morphogenesis GO:0048546 127 0.011
positive regulation of neuron projection regeneration GO:0070572 3 0.011
stem cell differentiation GO:0048863 117 0.011
purine ribonucleoside catabolic process GO:0046130 112 0.011
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 1 0.011
actin filament organization GO:0007015 126 0.011
protein localization GO:0008104 284 0.011
autophagic cell death GO:0048102 83 0.011
carbohydrate derivative catabolic process GO:1901136 118 0.011
modification dependent macromolecule catabolic process GO:0043632 79 0.011
gtp metabolic process GO:0046039 72 0.011
organonitrogen compound catabolic process GO:1901565 128 0.011
regulation of cell division GO:0051302 72 0.011
cellular amide metabolic process GO:0043603 80 0.011
mitochondrial membrane organization GO:0007006 3 0.011
syncytial blastoderm mitotic cell cycle GO:0035186 21 0.010
cellular protein complex assembly GO:0043623 71 0.010
regulation of ruffle assembly GO:1900027 1 0.010
protein localization to organelle GO:0033365 82 0.010
organelle assembly GO:0070925 198 0.010
humoral immune response GO:0006959 117 0.010
mitotic cell cycle phase transition GO:0044772 138 0.010
embryonic axis specification GO:0000578 107 0.010
axis specification GO:0009798 167 0.010
reproductive system development GO:0061458 74 0.010
negative regulation of cell proliferation GO:0008285 69 0.010
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.010
hemopoiesis GO:0030097 46 0.010

NELF-A disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.111
nervous system disease DOID:863 0 0.037
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016