Drosophila melanogaster

0 known processes

sop (Dmel_CG5920)

string of pearls

(Aliases: Dm01335,l(2)03848,dS2,Dmel\CG5920,CG5920,anon-EST:Posey202,RpS2,S2,l(2)k04603)

sop biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mitotic spindle organization GO:0007052 220 0.979
mitotic spindle elongation GO:0000022 81 0.933
spindle elongation GO:0051231 83 0.932
centrosome organization GO:0051297 163 0.903
spindle organization GO:0007051 253 0.895
centrosome cycle GO:0007098 137 0.721
centrosome duplication GO:0051298 121 0.684
translation GO:0006412 69 0.652
Yeast
microtubule organizing center organization GO:0031023 168 0.651
cytoplasmic translation GO:0002181 0 0.611
death GO:0016265 284 0.558
Worm
cell death GO:0008219 279 0.497
Worm
apoptotic process GO:0006915 159 0.473
Worm
larval development GO:0002164 104 0.471
Worm
negative regulation of cellular metabolic process GO:0031324 382 0.386
programmed cell death GO:0012501 257 0.375
Worm
ribosomal large subunit biogenesis GO:0042273 1 0.342
negative regulation of gene expression GO:0010629 387 0.292
catabolic process GO:0009056 409 0.262
endocytosis GO:0006897 310 0.250
cellular catabolic process GO:0044248 372 0.240
rrna processing GO:0006364 3 0.239
axon development GO:0061564 297 0.195
organic substance catabolic process GO:1901575 308 0.187
vesicle mediated transport GO:0016192 381 0.187
embryo development ending in birth or egg hatching GO:0009792 152 0.183
Worm
ribonucleoprotein complex assembly GO:0022618 23 0.178
ribonucleoprotein complex biogenesis GO:0022613 31 0.167
Yeast
ribonucleoprotein complex subunit organization GO:0071826 28 0.158
macromolecule catabolic process GO:0009057 161 0.156
regulation of cell cycle GO:0051726 291 0.149
determination of adult lifespan GO:0008340 137 0.145
dna metabolic process GO:0006259 227 0.136
negative regulation of response to stimulus GO:0048585 258 0.133
macromolecular complex assembly GO:0065003 256 0.133
negative regulation of protein metabolic process GO:0051248 85 0.128
body morphogenesis GO:0010171 2 0.126
positive regulation of response to stimulus GO:0048584 323 0.123
cellular macromolecule catabolic process GO:0044265 136 0.123
cell migration GO:0016477 238 0.118
molting cycle GO:0042303 56 0.115
immune system process GO:0002376 347 0.112
cellular protein modification process GO:0006464 438 0.098
regulation of cellular protein metabolic process GO:0032268 243 0.098
Yeast
cellular response to organic substance GO:0071310 132 0.095
rna processing GO:0006396 147 0.094
multicellular organismal aging GO:0010259 140 0.088
localization of cell GO:0051674 257 0.087
organelle fission GO:0048285 340 0.085
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.085
ncrna metabolic process GO:0034660 43 0.081
meiotic cell cycle process GO:1903046 132 0.081
mitotic nuclear division GO:0007067 213 0.072
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.072
regulation of response to stress GO:0080134 200 0.070
phosphorylation GO:0016310 294 0.069
regulation of multicellular organismal development GO:2000026 414 0.066
regulation of translation GO:0006417 56 0.065
Yeast
protein modification process GO:0036211 438 0.062
protein localization GO:0008104 284 0.060
growth GO:0040007 359 0.060
regulation of mitotic cell cycle GO:0007346 190 0.057
gene silencing by rna GO:0031047 57 0.056
oxoacid metabolic process GO:0043436 103 0.056
protein maturation GO:0051604 71 0.054
positive regulation of cell communication GO:0010647 250 0.054
establishment of protein localization GO:0045184 163 0.053
positive regulation of signal transduction GO:0009967 223 0.051
chromosome segregation GO:0007059 157 0.049
posttranscriptional gene silencing GO:0016441 46 0.048
negative regulation of signal transduction GO:0009968 206 0.048
regulation of gene expression epigenetic GO:0040029 128 0.048
cellular response to chemical stimulus GO:0070887 199 0.047
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.046
negative regulation of cellular response to oxidative stress GO:1900408 1 0.045
axonogenesis GO:0007409 290 0.045
posttranscriptional gene silencing by rna GO:0035194 45 0.044
phagocytosis GO:0006909 215 0.044
nuclear division GO:0000280 332 0.043
posttranscriptional regulation of gene expression GO:0010608 145 0.041
Yeast
negative regulation of cellular protein metabolic process GO:0032269 85 0.040
enzyme linked receptor protein signaling pathway GO:0007167 179 0.040
negative regulation of rna metabolic process GO:0051253 251 0.039
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.039
regulation of protein metabolic process GO:0051246 256 0.038
Yeast
rna localization GO:0006403 115 0.038
Yeast
single organism intracellular transport GO:1902582 207 0.038
Yeast
sex differentiation GO:0007548 81 0.038
regulation of intracellular signal transduction GO:1902531 236 0.037
endomembrane system organization GO:0010256 119 0.036
negative regulation of cellular component organization GO:0051129 108 0.036
organic substance transport GO:0071702 257 0.035
Yeast
central nervous system development GO:0007417 201 0.035
chromatin organization GO:0006325 207 0.034
gland development GO:0048732 191 0.034
negative regulation of mitotic cell cycle GO:0045930 109 0.034
modification dependent protein catabolic process GO:0019941 78 0.033
organonitrogen compound metabolic process GO:1901564 318 0.033
regulation of catalytic activity GO:0050790 185 0.033
Human
cellular protein catabolic process GO:0044257 83 0.032
regulation of localization GO:0032879 275 0.032
negative regulation of biosynthetic process GO:0009890 277 0.032
nucleobase containing compound transport GO:0015931 56 0.032
Yeast
regulation of molecular function GO:0065009 217 0.032
Human
mitotic dna damage checkpoint GO:0044773 74 0.031
regulation of cell death GO:0010941 173 0.031
protein processing GO:0016485 68 0.031
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.031
chemotaxis GO:0006935 249 0.030
negative regulation of translation GO:0017148 28 0.029
mitotic cytokinesis GO:0000281 50 0.028
cell motility GO:0048870 251 0.028
proteolysis GO:0006508 192 0.028
aging GO:0007568 143 0.028
cytoplasmic transport GO:0016482 130 0.028
Yeast
translational elongation GO:0006414 4 0.027
Yeast
gonad development GO:0008406 50 0.027
cellular macromolecular complex assembly GO:0034622 153 0.027
dendrite development GO:0016358 204 0.027
ribosome biogenesis GO:0042254 8 0.027
Yeast
oocyte development GO:0048599 124 0.026
protein catabolic process GO:0030163 101 0.026
regulation of cellular response to stress GO:0080135 89 0.025
dendrite morphogenesis GO:0048813 199 0.025
response to abiotic stimulus GO:0009628 341 0.025
negative regulation of cellular biosynthetic process GO:0031327 277 0.025
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.025
meiotic cell cycle GO:0051321 171 0.024
regulation of transport GO:0051049 181 0.024
response to organic substance GO:0010033 284 0.024
cholesterol transport GO:0030301 2 0.024
organic acid metabolic process GO:0006082 103 0.023
regulation of cellular amine metabolic process GO:0033238 3 0.023
regulation of transferase activity GO:0051338 58 0.023
Human
negative regulation of transcription dna templated GO:0045892 237 0.023
multicellular organismal reproductive behavior GO:0033057 110 0.023
cellular macromolecule localization GO:0070727 220 0.022
regulation of cellular amino acid metabolic process GO:0006521 0 0.022
regulation of cellular catabolic process GO:0031329 157 0.021
regulation of vesicle mediated transport GO:0060627 59 0.021
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.021
Yeast
heterocycle catabolic process GO:0046700 166 0.021
protein phosphorylation GO:0006468 169 0.021
response to oxygen containing compound GO:1901700 200 0.021
intracellular transport GO:0046907 228 0.021
Yeast
intracellular signal transduction GO:0035556 300 0.020
apoptotic signaling pathway GO:0097190 27 0.020
carboxylic acid metabolic process GO:0019752 92 0.020
secretion GO:0046903 109 0.020
nucleosome organization GO:0034728 59 0.020
dorsal ventral pattern formation GO:0009953 133 0.020
regulation of phosphate metabolic process GO:0019220 210 0.020
eye development GO:0001654 323 0.019
tissue death GO:0016271 102 0.019
organelle assembly GO:0070925 198 0.019
regulation of growth GO:0040008 233 0.019
protein transport GO:0015031 155 0.019
regulation of programmed cell death GO:0043067 152 0.019
brain development GO:0007420 120 0.019
cell division GO:0051301 248 0.019
jak stat cascade GO:0007259 49 0.018
negative regulation of cell cycle phase transition GO:1901988 103 0.018
negative regulation of signaling GO:0023057 219 0.018
cytoskeleton dependent cytokinesis GO:0061640 81 0.018
single organism catabolic process GO:0044712 228 0.018
negative regulation of cell death GO:0060548 81 0.017
development of primary sexual characteristics GO:0045137 50 0.017
cell recognition GO:0008037 102 0.017
nucleosome assembly GO:0006334 35 0.017
ncrna processing GO:0034470 30 0.017
positive regulation of developmental process GO:0051094 143 0.017
regulation of establishment of protein localization GO:0070201 61 0.017
gene silencing GO:0016458 138 0.016
camera type eye development GO:0043010 4 0.016
dna packaging GO:0006323 91 0.016
histolysis GO:0007559 102 0.016
intrinsic apoptotic signaling pathway GO:0097193 16 0.016
reproductive system development GO:0061458 74 0.015
positive regulation of intracellular signal transduction GO:1902533 116 0.015
regulation of developmental growth GO:0048638 174 0.015
small molecule metabolic process GO:0044281 305 0.015
response to external biotic stimulus GO:0043207 293 0.015
negative regulation of developmental process GO:0051093 201 0.015
positive regulation of cell migration GO:0030335 2 0.015
cell proliferation GO:0008283 299 0.015
negative regulation of cell cycle process GO:0010948 109 0.015
secretion by cell GO:0032940 101 0.014
signal transduction by phosphorylation GO:0023014 107 0.014
cellular response to biotic stimulus GO:0071216 4 0.014
positive regulation of phosphorus metabolic process GO:0010562 139 0.014
regulation of cellular ketone metabolic process GO:0010565 3 0.014
positive regulation of cellular protein metabolic process GO:0032270 118 0.014
Yeast
cellular response to dna damage stimulus GO:0006974 223 0.014
neuron recognition GO:0008038 101 0.014
dna damage checkpoint GO:0000077 78 0.014
regulation of mrna metabolic process GO:1903311 72 0.014
establishment of localization in cell GO:0051649 402 0.014
Yeast
mrna metabolic process GO:0016071 124 0.014
positive regulation of multicellular organismal process GO:0051240 143 0.014
modification dependent macromolecule catabolic process GO:0043632 79 0.014
regulation of mitosis GO:0007088 56 0.014
cellular nitrogen compound catabolic process GO:0044270 165 0.014
purine containing compound metabolic process GO:0072521 155 0.014
rna interference GO:0016246 27 0.014
sister chromatid segregation GO:0000819 92 0.013
regulation of establishment of protein localization to plasma membrane GO:0090003 7 0.013
axon guidance GO:0007411 233 0.013
hematopoietic or lymphoid organ development GO:0048534 57 0.013
axis specification GO:0009798 167 0.013
regulation of phosphorus metabolic process GO:0051174 210 0.013
regulation of cell cycle process GO:0010564 181 0.013
oocyte construction GO:0007308 112 0.013
negative regulation of nucleic acid templated transcription GO:1903507 240 0.013
protein complex biogenesis GO:0070271 201 0.013
nucleobase containing compound catabolic process GO:0034655 165 0.013
embryonic morphogenesis GO:0048598 206 0.013
regulation of response to oxidative stress GO:1902882 4 0.013
regulation of cellular protein catabolic process GO:1903362 44 0.013
negative regulation of peptidyl tyrosine phosphorylation GO:0050732 6 0.013
digestive tract morphogenesis GO:0048546 127 0.012
positive regulation of translation GO:0045727 12 0.012
Yeast
cellular protein localization GO:0034613 160 0.012
regulation of phosphorylation GO:0042325 147 0.012
response to starvation GO:0042594 97 0.012
response to biotic stimulus GO:0009607 294 0.012
positive regulation of growth GO:0045927 75 0.012
tissue morphogenesis GO:0048729 297 0.012
response to other organism GO:0051707 293 0.012
dna conformation change GO:0071103 105 0.012
notch signaling pathway GO:0007219 120 0.012
cellular amino acid metabolic process GO:0006520 61 0.012
regulation of protein localization GO:0032880 76 0.011
immune system development GO:0002520 57 0.011
positive regulation of phosphorylation GO:0042327 87 0.011
genitalia development GO:0048806 26 0.011
regulation of glucan biosynthetic process GO:0010962 1 0.011
protein modification by small protein conjugation GO:0032446 79 0.011
negative regulation of apoptotic process GO:0043066 63 0.011
maintenance of location GO:0051235 73 0.011
regulation of cell division GO:0051302 72 0.011
purine ribonucleotide metabolic process GO:0009150 145 0.011
mitotic dna integrity checkpoint GO:0044774 75 0.011
regulation of membrane depolarization GO:0003254 1 0.011
regionalization GO:0003002 416 0.011
negative regulation of catalytic activity GO:0043086 42 0.011
cytokinesis GO:0000910 90 0.011
positive regulation of protein phosphorylation GO:0001934 34 0.011
regulation of kinase activity GO:0043549 53 0.011
negative regulation of cell cycle GO:0045786 116 0.011
positive regulation of protein metabolic process GO:0051247 128 0.011
Yeast
regulation of apoptotic process GO:0042981 130 0.010
positive regulation of signaling GO:0023056 243 0.010
positive regulation of phosphate metabolic process GO:0045937 139 0.010
membrane organization GO:0061024 112 0.010
neuron projection guidance GO:0097485 241 0.010
nuclear transport GO:0051169 72 0.010
Yeast

sop disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.045
immune system disease DOID:2914 0 0.021
anemia DOID:2355 0 0.021
hematopoietic system disease DOID:74 0 0.021