Drosophila melanogaster

29 known processes

mus308 (Dmel_CG6019)

mutagen-sensitive 308

(Aliases: 0443/09,Dmel\CG6019,CG6019,AAF54858,mus-308,Pol theta,Nuc3,Mus308)

mus308 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
double strand break repair GO:0006302 26 0.975
double strand break repair via synthesis dependent strand annealing GO:0045003 6 0.968
non recombinational repair GO:0000726 7 0.949
cellular response to dna damage stimulus GO:0006974 223 0.930
dna synthesis involved in dna repair GO:0000731 5 0.903
double strand break repair via nonhomologous end joining GO:0006303 5 0.839
dna damage checkpoint GO:0000077 78 0.630
dna repair GO:0006281 54 0.620
translesion synthesis GO:0019985 2 0.606
telomere organization GO:0032200 21 0.590
dna double strand break processing GO:0000729 3 0.559
double strand break repair via homologous recombination GO:0000724 13 0.551
nucleotide excision repair GO:0006289 8 0.545
negative regulation of cell cycle phase transition GO:1901988 103 0.465
chromosome segregation GO:0007059 157 0.414
Fly
mitotic dna damage checkpoint GO:0044773 74 0.399
postreplication repair GO:0006301 2 0.398
dna biosynthetic process GO:0071897 24 0.390
Human
negative regulation of cell cycle process GO:0010948 109 0.369
mitotic cell cycle phase transition GO:0044772 138 0.366
snrna 3 end processing GO:0034472 14 0.322
negative regulation of mitotic cell cycle GO:0045930 109 0.311
dna metabolic process GO:0006259 227 0.302
meiotic chromosome segregation GO:0045132 59 0.287
Fly
chromosome separation GO:0051304 42 0.270
telomere maintenance via recombination GO:0000722 1 0.258
mitotic g2 dna damage checkpoint GO:0007095 69 0.208
mitotic g2 m transition checkpoint GO:0044818 70 0.198
dna geometric change GO:0032392 16 0.195
mitotic dna integrity checkpoint GO:0044774 75 0.193
mitotic cell cycle checkpoint GO:0007093 88 0.188
negative regulation of cell cycle GO:0045786 116 0.174
regulation of cell cycle process GO:0010564 181 0.171
cell cycle phase transition GO:0044770 140 0.155
regulation of cell cycle phase transition GO:1901987 130 0.140
response to abiotic stimulus GO:0009628 341 0.115
cell cycle checkpoint GO:0000075 95 0.114
g2 dna damage checkpoint GO:0031572 69 0.095
meiotic cell cycle process GO:1903046 132 0.091
Fly
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.086
response to ionizing radiation GO:0010212 32 0.083
organelle fission GO:0048285 340 0.081
Fly
purine nucleoside catabolic process GO:0006152 112 0.072
Human
nuclear division GO:0000280 332 0.071
Fly
regulation of dna repair GO:0006282 5 0.071
regulation of mitotic cell cycle phase transition GO:1901990 130 0.070
recombinational repair GO:0000725 13 0.065
organic substance catabolic process GO:1901575 308 0.064
Human
meiotic chromosome separation GO:0051307 8 0.063
telomere maintenance GO:0000723 21 0.061
regulation of response to dna damage stimulus GO:2001020 23 0.061
dna integrity checkpoint GO:0031570 81 0.058
regulation of mitotic cell cycle GO:0007346 190 0.056
purine ribonucleoside metabolic process GO:0046128 127 0.056
Human
purine ribonucleotide catabolic process GO:0009154 109 0.054
Human
ribonucleotide metabolic process GO:0009259 145 0.052
Human
aging GO:0007568 143 0.051
glycosyl compound catabolic process GO:1901658 112 0.049
Human
negative regulation of cellular metabolic process GO:0031324 382 0.048
response to radiation GO:0009314 155 0.046
meiotic cell cycle GO:0051321 171 0.045
Fly
chromosome organization GO:0051276 360 0.045
Fly
organophosphate catabolic process GO:0046434 112 0.044
Human
meiosis i GO:0007127 59 0.044
intracellular signal transduction GO:0035556 300 0.043
compound eye photoreceptor cell differentiation GO:0001751 140 0.043
reciprocal meiotic recombination GO:0007131 19 0.043
regulation of double strand break repair GO:2000779 3 0.043
positive regulation of nucleic acid templated transcription GO:1903508 266 0.043
regulation of cell cycle GO:0051726 291 0.041
ribonucleoside catabolic process GO:0042454 112 0.041
Human
mitotic sister chromatid separation GO:0051306 30 0.040
regulation of developmental growth GO:0048638 174 0.040
atp metabolic process GO:0046034 49 0.039
Human
catabolic process GO:0009056 409 0.039
Human
modification dependent macromolecule catabolic process GO:0043632 79 0.039
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.038
single organism biosynthetic process GO:0044711 206 0.038
response to alkaloid GO:0043279 26 0.038
response to uv GO:0009411 24 0.037
purine nucleotide catabolic process GO:0006195 109 0.037
Human
dna recombination GO:0006310 32 0.037
positive regulation of transcription dna templated GO:0045893 266 0.036
cellular catabolic process GO:0044248 372 0.036
Human
mitotic dna replication checkpoint GO:0033314 5 0.036
nucleoside phosphate metabolic process GO:0006753 162 0.036
Human
organonitrogen compound metabolic process GO:1901564 318 0.035
Human
regulation of nervous system development GO:0051960 248 0.035
regulation of phosphorylation GO:0042325 147 0.035
purine ribonucleoside catabolic process GO:0046130 112 0.035
Human
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.034
multicellular organismal aging GO:0010259 140 0.034
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.033
Human
signal transduction in response to dna damage GO:0042770 3 0.032
wing disc morphogenesis GO:0007472 344 0.032
dna amplification GO:0006277 11 0.032
embryo development ending in birth or egg hatching GO:0009792 152 0.031
snrna processing GO:0016180 14 0.031
purine containing compound catabolic process GO:0072523 112 0.031
Human
small molecule metabolic process GO:0044281 305 0.031
Human
nucleotide metabolic process GO:0009117 161 0.030
Human
dna conformation change GO:0071103 105 0.030
proteasomal protein catabolic process GO:0010498 59 0.030
regulation of cellular response to stress GO:0080135 89 0.029
negative regulation of response to stimulus GO:0048585 258 0.028
regulation of actin filament polymerization GO:0030833 25 0.027
purine nucleotide metabolic process GO:0006163 146 0.027
Human
regulation of catabolic process GO:0009894 170 0.027
positive regulation of macromolecule metabolic process GO:0010604 405 0.026
ribonucleoside metabolic process GO:0009119 127 0.026
Human
cell proliferation GO:0008283 299 0.026
regulation of intracellular signal transduction GO:1902531 236 0.026
carbohydrate derivative metabolic process GO:1901135 217 0.026
Human
cell aging GO:0007569 2 0.026
neurological system process GO:0050877 358 0.026
protein catabolic process GO:0030163 101 0.026
anatomical structure homeostasis GO:0060249 97 0.025
nucleobase containing small molecule metabolic process GO:0055086 174 0.025
Human
cellular response to ionizing radiation GO:0071479 15 0.025
amine metabolic process GO:0009308 12 0.025
purine ribonucleotide metabolic process GO:0009150 145 0.025
Human
nucleoside triphosphate metabolic process GO:0009141 120 0.025
Human
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.025
regulation of dna metabolic process GO:0051052 34 0.024
reciprocal dna recombination GO:0035825 19 0.024
regulation of neurogenesis GO:0050767 158 0.024
cuticle development GO:0042335 86 0.024
antimicrobial humoral response GO:0019730 99 0.024
post embryonic hemopoiesis GO:0035166 17 0.024
germarium derived oocyte fate determination GO:0007294 26 0.023
Fly
nucleoside triphosphate catabolic process GO:0009143 108 0.023
Human
cell cycle dna replication GO:0044786 23 0.023
regulation of dna recombination GO:0000018 4 0.023
nucleoside metabolic process GO:0009116 127 0.023
Human
regulation of multicellular organismal development GO:2000026 414 0.023
regulation of cell morphogenesis GO:0022604 163 0.023
carbohydrate derivative catabolic process GO:1901136 118 0.022
Human
resolution of meiotic recombination intermediates GO:0000712 6 0.022
regulation of cellular catabolic process GO:0031329 157 0.022
positive regulation of biosynthetic process GO:0009891 316 0.022
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.021
Human
body morphogenesis GO:0010171 2 0.021
actin filament polymerization GO:0030041 27 0.021
negative regulation of catabolic process GO:0009895 36 0.021
negative regulation of cell division GO:0051782 17 0.021
macromolecule catabolic process GO:0009057 161 0.021
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 11 0.021
protein complex biogenesis GO:0070271 201 0.021
actin filament based process GO:0030029 220 0.021
growth GO:0040007 359 0.020
multi multicellular organism process GO:0044706 123 0.020
positive regulation of cellular amine metabolic process GO:0033240 0 0.020
single organism intracellular transport GO:1902582 207 0.020
ribose phosphate metabolic process GO:0019693 145 0.020
Human
ribonucleoside triphosphate metabolic process GO:0009199 119 0.020
Human
regulation of organelle organization GO:0033043 196 0.020
multicellular organism growth GO:0035264 46 0.019
organic cyclic compound catabolic process GO:1901361 168 0.019
Human
transcription from rna polymerase ii promoter GO:0006366 368 0.019
immune response GO:0006955 246 0.019
cellular component assembly involved in morphogenesis GO:0010927 151 0.019
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.019
Human
purine nucleoside monophosphate catabolic process GO:0009128 38 0.019
Human
ribonucleoside monophosphate catabolic process GO:0009158 39 0.019
Human
neuropeptide signaling pathway GO:0007218 45 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.018
proteolysis GO:0006508 192 0.018
negative regulation of cellular biosynthetic process GO:0031327 277 0.018
cellular amine metabolic process GO:0044106 12 0.018
regulation of cellular protein metabolic process GO:0032268 243 0.018
regulation of phosphate metabolic process GO:0019220 210 0.018
cell division GO:0051301 248 0.018
regulation of cell division GO:0051302 72 0.017
rna processing GO:0006396 147 0.017
cellular protein catabolic process GO:0044257 83 0.017
determination of adult lifespan GO:0008340 137 0.017
regulation of chromosome organization GO:0033044 64 0.017
cellular macromolecule catabolic process GO:0044265 136 0.017
humoral immune response GO:0006959 117 0.017
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.016
nucleobase containing compound catabolic process GO:0034655 165 0.016
Human
developmental growth GO:0048589 280 0.016
regulation of cell shape GO:0008360 113 0.016
ribonucleoside monophosphate metabolic process GO:0009161 51 0.016
Human
response to x ray GO:0010165 8 0.016
cellular nitrogen compound catabolic process GO:0044270 165 0.016
Human
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.016
response to oxygen containing compound GO:1901700 200 0.016
nucleotide catabolic process GO:0009166 109 0.016
Human
organophosphate metabolic process GO:0019637 195 0.016
Human
oocyte fate determination GO:0030716 27 0.016
Fly
replication fork processing GO:0031297 0 0.016
purine nucleoside metabolic process GO:0042278 127 0.016
Human
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.016
negative regulation of sister chromatid segregation GO:0033046 13 0.016
chromatin remodeling GO:0006338 72 0.016
multi organism behavior GO:0051705 175 0.016
regionalization GO:0003002 416 0.016
Fly
regulation of nuclear division GO:0051783 58 0.016
cellular amino acid metabolic process GO:0006520 61 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.016
positive regulation of cellular catabolic process GO:0031331 95 0.015
regulation of neuron differentiation GO:0045664 103 0.015
chromatin organization GO:0006325 207 0.015
negative regulation of g2 m transition of mitotic cell cycle GO:0010972 8 0.015
negative regulation of meiotic cell cycle GO:0051447 2 0.015
endocytosis GO:0006897 310 0.015
purine containing compound metabolic process GO:0072521 155 0.015
Human
carboxylic acid metabolic process GO:0019752 92 0.015
negative regulation of signal transduction GO:0009968 206 0.015
centrosome cycle GO:0007098 137 0.014
photoreceptor cell differentiation GO:0046530 170 0.014
defense response to other organism GO:0098542 225 0.014
organonitrogen compound catabolic process GO:1901565 128 0.014
Human
response to alcohol GO:0097305 95 0.014
peptidyl lysine acetylation GO:0018394 39 0.014
regulation of anatomical structure morphogenesis GO:0022603 242 0.014
rna 3 end processing GO:0031123 45 0.014
gtp catabolic process GO:0006184 72 0.014
regulation of rna splicing GO:0043484 69 0.014
regulation of cellular protein catabolic process GO:1903362 44 0.014
regulation of cellular amine metabolic process GO:0033238 3 0.014
snrna metabolic process GO:0016073 14 0.014
cilium organization GO:0044782 41 0.014
response to light stimulus GO:0009416 124 0.014
regulation of catalytic activity GO:0050790 185 0.014
ribonucleoside triphosphate catabolic process GO:0009203 108 0.013
Human
actin cytoskeleton organization GO:0030036 206 0.013
reproductive behavior GO:0019098 122 0.013
meiotic nuclear division GO:0007126 151 0.013
Fly
purine nucleoside triphosphate metabolic process GO:0009144 119 0.013
Human
nucleoside catabolic process GO:0009164 112 0.013
Human
protein modification process GO:0036211 438 0.013
production of molecular mediator of immune response GO:0002440 46 0.013
response to other organism GO:0051707 293 0.013
sex differentiation GO:0007548 81 0.013
nucleoside monophosphate catabolic process GO:0009125 39 0.013
Human
modification dependent protein catabolic process GO:0019941 78 0.013
mitotic sister chromatid segregation GO:0000070 87 0.013
glycosyl compound metabolic process GO:1901657 127 0.013
Human
actin polymerization or depolymerization GO:0008154 31 0.013
anterior posterior pattern specification GO:0009952 136 0.013
Fly
cell death GO:0008219 279 0.013
regulation of actin cytoskeleton organization GO:0032956 42 0.013
reproductive structure development GO:0048608 74 0.013
regulation of ras protein signal transduction GO:0046578 93 0.013
ribonucleotide catabolic process GO:0009261 109 0.013
Human
response to oxidative stress GO:0006979 86 0.013
vesicle mediated transport GO:0016192 381 0.013
atp dependent chromatin remodeling GO:0043044 22 0.012
intracellular mrna localization GO:0008298 66 0.012
Fly
negative regulation of cell communication GO:0010648 223 0.012
death GO:0016265 284 0.012
connective tissue development GO:0061448 3 0.012
response to organic substance GO:0010033 284 0.012
negative regulation of cell cycle g2 m phase transition GO:1902750 8 0.012
chitin based cuticle development GO:0040003 49 0.012
positive regulation of protein complex assembly GO:0031334 22 0.012
immune effector process GO:0002252 98 0.012
ubiquitin dependent protein catabolic process GO:0006511 78 0.012
dopamine biosynthetic process GO:0042416 3 0.012
single organism catabolic process GO:0044712 228 0.012
Human
mitotic nuclear division GO:0007067 213 0.012
defense response GO:0006952 300 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
response to camptothecin GO:1901563 2 0.012
immune system process GO:0002376 347 0.012
response to external biotic stimulus GO:0043207 293 0.011
cellular protein complex assembly GO:0043623 71 0.011
multi organism reproductive behavior GO:0044705 121 0.011
dna methylation or demethylation GO:0044728 4 0.011
signal transduction by phosphorylation GO:0023014 107 0.011
axonogenesis GO:0007409 290 0.011
positive regulation of nervous system development GO:0051962 69 0.011
regulation of mitotic sister chromatid segregation GO:0033047 28 0.011
regulation of proteolysis GO:0030162 87 0.011
negative regulation of nucleic acid templated transcription GO:1903507 240 0.011
molting cycle process GO:0022404 29 0.011
regulation of protein catabolic process GO:0042176 55 0.011
regulation of mitosis GO:0007088 56 0.011
regulation of molecular function GO:0065009 217 0.011
dna packaging GO:0006323 91 0.011
regulation of sister chromatid segregation GO:0033045 28 0.010
macromolecular complex assembly GO:0065003 256 0.010
positive regulation of rna biosynthetic process GO:1902680 266 0.010
neuroblast proliferation GO:0007405 74 0.010
embryonic development via the syncytial blastoderm GO:0001700 148 0.010
positive regulation of signaling GO:0023056 243 0.010
regulation of protein metabolic process GO:0051246 256 0.010
morphogenesis of a branching epithelium GO:0061138 45 0.010
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.010
gtp metabolic process GO:0046039 72 0.010
chorion containing eggshell formation GO:0007304 105 0.010
aromatic compound catabolic process GO:0019439 166 0.010
Human
regulation of phosphorus metabolic process GO:0051174 210 0.010
positive regulation of cellular biosynthetic process GO:0031328 316 0.010

mus308 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.047
disease of cellular proliferation DOID:14566 0 0.047
thoracic cancer DOID:5093 0 0.040
organ system cancer DOID:0050686 0 0.040
disease of anatomical entity DOID:7 0 0.012