Drosophila melanogaster

217 known processes

drk (Dmel_CG6033)

downstream of receptor kinase

(Aliases: Su(sev)R1,P1112,crkl,Drk/Grb2,CG6033,GRB2,E(sev)2B,Drk,24/1,l(2)10626,l(2)k13809,DRK,Dmel\CG6033,Grb2/drk,Grb/drk,Grb2)

drk biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of response to stress GO:0080134 200 0.997
negative regulation of cellular metabolic process GO:0031324 382 0.995
developmental growth GO:0048589 280 0.994
cell motility GO:0048870 251 0.993
Worm
enzyme linked receptor protein signaling pathway GO:0007167 179 0.993
regulation of nervous system development GO:0051960 248 0.991
regulation of r7 cell differentiation GO:0045676 15 0.987
cognition GO:0050890 141 0.986
regulation of multicellular organismal development GO:2000026 414 0.984
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.981
regulation of protein metabolic process GO:0051246 256 0.978
imaginal disc derived wing morphogenesis GO:0007476 337 0.978
learning or memory GO:0007611 141 0.978
immune system process GO:0002376 347 0.977
regulation of erbb signaling pathway GO:1901184 42 0.971
cell migration GO:0016477 238 0.965
Worm
neurological system process GO:0050877 358 0.960
positive regulation of phosphate metabolic process GO:0045937 139 0.958
negative regulation of signaling GO:0023057 219 0.955
localization of cell GO:0051674 257 0.953
Worm
regulation of response to external stimulus GO:0032101 115 0.951
epidermal growth factor receptor signaling pathway GO:0007173 58 0.951
associative learning GO:0008306 65 0.949
epithelium migration GO:0090132 148 0.946
epithelial cell migration GO:0010631 148 0.941
gliogenesis GO:0042063 80 0.937
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.937
single organism behavior GO:0044708 391 0.936
regulation of growth GO:0040008 233 0.933
regulation of phosphorylation GO:0042325 147 0.933
tube development GO:0035295 244 0.932
regulation of cell development GO:0060284 215 0.931
negative regulation of response to stimulus GO:0048585 258 0.918
regulation of protein kinase activity GO:0045859 51 0.914
immune response GO:0006955 246 0.913
positive regulation of macromolecule metabolic process GO:0010604 405 0.910
negative regulation of synaptic growth at neuromuscular junction GO:0045886 39 0.901
axon development GO:0061564 297 0.897
cell division GO:0051301 248 0.896
embryonic morphogenesis GO:0048598 206 0.894
Mouse
regulation of cell differentiation GO:0045595 302 0.880
eye morphogenesis GO:0048592 260 0.877
cell growth GO:0016049 108 0.871
small molecule metabolic process GO:0044281 305 0.870
appendage development GO:0048736 401 0.867
regulation of neurogenesis GO:0050767 158 0.865
response to oxidative stress GO:0006979 86 0.857
positive regulation of response to stimulus GO:0048584 323 0.855
protein phosphorylation GO:0006468 169 0.852
wing disc morphogenesis GO:0007472 344 0.851
imaginal disc derived appendage development GO:0048737 399 0.851
regulation of developmental growth GO:0048638 174 0.848
growth GO:0040007 359 0.847
response to organic substance GO:0010033 284 0.847
Human Mouse
regulation of apoptotic process GO:0042981 130 0.845
regulation of immune response GO:0050776 118 0.838
cellular response to chemical stimulus GO:0070887 199 0.815
Human Mouse
asymmetric neuroblast division GO:0055059 33 0.803
cellular ketone metabolic process GO:0042180 24 0.802
negative regulation of phosphorylation GO:0042326 35 0.801
peptidyl amino acid modification GO:0018193 105 0.791
axonogenesis GO:0007409 290 0.788
muscle structure development GO:0061061 224 0.780
Worm
neural precursor cell proliferation GO:0061351 75 0.774
regulation of intracellular signal transduction GO:1902531 236 0.773
guanosine containing compound catabolic process GO:1901069 74 0.767
negative regulation of erbb signaling pathway GO:1901185 29 0.762
negative regulation of cell communication GO:0010648 223 0.759
regulation of cellular protein metabolic process GO:0032268 243 0.758
behavioral response to ethanol GO:0048149 49 0.757
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.749
positive regulation of rna biosynthetic process GO:1902680 266 0.748
regulation of kinase activity GO:0043549 53 0.739
organonitrogen compound metabolic process GO:1901564 318 0.737
tissue migration GO:0090130 155 0.737
hemopoiesis GO:0030097 46 0.737
immune effector process GO:0002252 98 0.728
positive regulation of biosynthetic process GO:0009891 316 0.721
neuroblast proliferation GO:0007405 74 0.721
cellular protein modification process GO:0006464 438 0.721
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.714
nucleoside catabolic process GO:0009164 112 0.706
learning GO:0007612 75 0.698
response to ethanol GO:0045471 59 0.695
death GO:0016265 284 0.694
positive regulation of cellular protein metabolic process GO:0032270 118 0.694
regulation of response to nutrient levels GO:0032107 18 0.694
regulation of cell death GO:0010941 173 0.693
positive regulation of cell communication GO:0010647 250 0.685
positive regulation of gene expression GO:0010628 290 0.682
open tracheal system development GO:0007424 204 0.681
regulation of phosphorus metabolic process GO:0051174 210 0.673
purine containing compound catabolic process GO:0072523 112 0.671
positive regulation of phosphorus metabolic process GO:0010562 139 0.668
regulation of organ morphogenesis GO:2000027 78 0.666
regulation of cellular catabolic process GO:0031329 157 0.660
regulation of anatomical structure size GO:0090066 163 0.658
Mouse
regulation of phosphate metabolic process GO:0019220 210 0.654
gtp catabolic process GO:0006184 72 0.653
purine ribonucleoside metabolic process GO:0046128 127 0.649
brain development GO:0007420 120 0.646
erbb signaling pathway GO:0038127 58 0.644
ribonucleoside catabolic process GO:0042454 112 0.642
programmed cell death GO:0012501 257 0.640
regulation of cellular response to stress GO:0080135 89 0.640
eye photoreceptor cell differentiation GO:0001754 145 0.639
establishment of protein localization GO:0045184 163 0.639
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.639
phosphorylation GO:0016310 294 0.634
nucleoside triphosphate metabolic process GO:0009141 120 0.632
regulation of programmed cell death GO:0043067 152 0.628
synapse organization GO:0050808 196 0.622
hematopoietic or lymphoid organ development GO:0048534 57 0.621
cell death GO:0008219 279 0.616
negative regulation of signal transduction GO:0009968 206 0.613
guanosine containing compound metabolic process GO:1901068 74 0.601
intracellular signal transduction GO:0035556 300 0.598
regulation of protein modification process GO:0031399 112 0.595
olfactory learning GO:0008355 56 0.595
sensory organ morphogenesis GO:0090596 260 0.586
ras protein signal transduction GO:0007265 88 0.581
imaginal disc derived appendage morphogenesis GO:0035114 395 0.574
negative regulation of cellular protein metabolic process GO:0032269 85 0.573
g protein coupled receptor signaling pathway GO:0007186 136 0.572
positive regulation of protein metabolic process GO:0051247 128 0.568
axon extension GO:0048675 32 0.568
positive regulation of transport GO:0051050 92 0.562
positive regulation of cellular biosynthetic process GO:0031328 316 0.561
negative regulation of protein phosphorylation GO:0001933 17 0.554
head development GO:0060322 135 0.552
adult behavior GO:0030534 137 0.550
gtp metabolic process GO:0046039 72 0.549
regulation of system process GO:0044057 36 0.544
tube morphogenesis GO:0035239 191 0.543
positive regulation of nucleic acid templated transcription GO:1903508 266 0.540
chromosome organization GO:0051276 360 0.537
photoreceptor cell differentiation GO:0046530 170 0.534
positive regulation of developmental process GO:0051094 143 0.532
ovarian follicle cell migration GO:0007297 121 0.532
regulation of cellular amino acid metabolic process GO:0006521 0 0.530
negative regulation of cellular biosynthetic process GO:0031327 277 0.525
catabolic process GO:0009056 409 0.521
regulation of ras gtpase activity GO:0032318 38 0.517
cellular protein complex assembly GO:0043623 71 0.512
Yeast Mouse
transcription from rna polymerase ii promoter GO:0006366 368 0.511
dna metabolic process GO:0006259 227 0.511
positive regulation of phosphorylation GO:0042327 87 0.510
ameboidal type cell migration GO:0001667 151 0.509
positive regulation of multicellular organismal process GO:0051240 143 0.509
post embryonic appendage morphogenesis GO:0035120 385 0.508
immune system development GO:0002520 57 0.502
stress activated mapk cascade GO:0051403 52 0.499
regulation of catabolic process GO:0009894 170 0.490
myotube differentiation GO:0014902 46 0.488
regulation of localization GO:0032879 275 0.487
regulation of autophagy GO:0010506 62 0.487
respiratory system development GO:0060541 213 0.486
stress activated protein kinase signaling cascade GO:0031098 55 0.479
organic substance catabolic process GO:1901575 308 0.477
positive regulation of photoreceptor cell differentiation GO:0046534 12 0.477
nuclear division GO:0000280 332 0.467
regulation of molecular function GO:0065009 217 0.465
regulation of cell morphogenesis GO:0022604 163 0.463
morphogenesis of an epithelium GO:0002009 276 0.456
Mouse
neuromuscular junction development GO:0007528 149 0.451
appendage morphogenesis GO:0035107 397 0.449
regulation of behavior GO:0050795 75 0.448
positive regulation of transcription dna templated GO:0045893 266 0.435
purine nucleoside catabolic process GO:0006152 112 0.434
neuroblast division GO:0055057 35 0.432
organic substance transport GO:0071702 257 0.432
developmental cell growth GO:0048588 52 0.431
nucleotide catabolic process GO:0009166 109 0.427
negative regulation of protein modification process GO:0031400 29 0.426
vesicle mediated transport GO:0016192 381 0.425
Human Yeast Worm
small gtpase mediated signal transduction GO:0007264 88 0.423
digestive tract morphogenesis GO:0048546 127 0.423
nuclear transport GO:0051169 72 0.423
rhythmic behavior GO:0007622 76 0.422
actin filament based process GO:0030029 220 0.413
oxoacid metabolic process GO:0043436 103 0.409
cellular macromolecular complex assembly GO:0034622 153 0.406
Yeast Mouse
positive regulation of erk1 and erk2 cascade GO:0070374 36 0.401
nucleoside metabolic process GO:0009116 127 0.398
single organism catabolic process GO:0044712 228 0.398
somatic stem cell division GO:0048103 37 0.397
response to wounding GO:0009611 94 0.394
chemotaxis GO:0006935 249 0.390
positive regulation of cell proliferation GO:0008284 47 0.389
regulation of ras protein signal transduction GO:0046578 93 0.387
regulation of immune system process GO:0002682 176 0.387
regulation of cell projection organization GO:0031344 92 0.384
Worm
cell type specific apoptotic process GO:0097285 38 0.382
compound eye photoreceptor cell differentiation GO:0001751 140 0.381
negative regulation of apoptotic process GO:0043066 63 0.380
neuron projection guidance GO:0097485 241 0.377
negative regulation of developmental process GO:0051093 201 0.374
organonitrogen compound catabolic process GO:1901565 128 0.373
circadian behavior GO:0048512 76 0.373
response to organic cyclic compound GO:0014070 89 0.373
actin cytoskeleton organization GO:0030036 206 0.370
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.369
positive regulation of molecular function GO:0044093 136 0.367
response to nitrogen compound GO:1901698 90 0.367
Human
negative regulation of immune system process GO:0002683 50 0.367
carboxylic acid metabolic process GO:0019752 92 0.364
negative regulation of autophagy GO:0010507 16 0.359
erk1 and erk2 cascade GO:0070371 39 0.356
negative regulation of transcription dna templated GO:0045892 237 0.352
compound eye photoreceptor fate commitment GO:0001752 36 0.352
positive regulation of signal transduction GO:0009967 223 0.350
positive regulation of immune system process GO:0002684 68 0.350
germ line cyst formation GO:0048134 44 0.345
cellular catabolic process GO:0044248 372 0.342
nucleocytoplasmic transport GO:0006913 72 0.335
regulation of transferase activity GO:0051338 58 0.335
locomotory behavior GO:0007626 176 0.333
negative regulation of protein metabolic process GO:0051248 85 0.330
regulation of small gtpase mediated signal transduction GO:0051056 93 0.327
positive regulation of protein modification process GO:0031401 58 0.325
posttranscriptional regulation of gene expression GO:0010608 145 0.322
morphogenesis of follicular epithelium GO:0016333 36 0.321
regulation of epithelial cell migration GO:0010632 12 0.321
tissue morphogenesis GO:0048729 297 0.319
Mouse
regulation of cell shape GO:0008360 113 0.316
positive regulation of wound healing GO:0090303 12 0.314
response to abiotic stimulus GO:0009628 341 0.313
Human
response to alcohol GO:0097305 95 0.312
epithelial cell development GO:0002064 274 0.308
wound healing GO:0042060 75 0.308
cell proliferation GO:0008283 299 0.307
negative regulation of phosphate metabolic process GO:0045936 45 0.303
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 29 0.301
border follicle cell migration GO:0007298 113 0.300
mitotic cell cycle phase transition GO:0044772 138 0.299
organophosphate catabolic process GO:0046434 112 0.298
regulation of cell migration GO:0030334 22 0.295
regulation of cell cycle process GO:0010564 181 0.292
rho protein signal transduction GO:0007266 14 0.291
memory GO:0007613 94 0.291
circulatory system process GO:0003013 37 0.286
regulation of wound healing GO:0061041 13 0.284
ovarian follicle cell development GO:0030707 248 0.283
protein localization GO:0008104 284 0.282
cellular response to growth factor stimulus GO:0071363 30 0.280
Mouse
apoptotic process GO:0006915 159 0.279
reproductive structure development GO:0048608 74 0.279
Mouse Worm
autophagy GO:0006914 108 0.278
regulation of cellular ketone metabolic process GO:0010565 3 0.274
peptidyl tyrosine modification GO:0018212 24 0.273
regulation of protein phosphorylation GO:0001932 64 0.272
positive regulation of intracellular signal transduction GO:1902533 116 0.271
purine containing compound metabolic process GO:0072521 155 0.267
positive regulation of rna metabolic process GO:0051254 271 0.267
mapk cascade GO:0000165 107 0.264
regulation of endocytosis GO:0030100 37 0.261
negative regulation of programmed cell death GO:0043069 72 0.259
epithelial cell differentiation GO:0030855 322 0.258
innate immune response GO:0045087 144 0.255
endomembrane system organization GO:0010256 119 0.254
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.254
regulation of cell cycle GO:0051726 291 0.252
positive regulation of cell migration GO:0030335 2 0.250
multicellular organism growth GO:0035264 46 0.249
positive regulation of cell death GO:0010942 69 0.249
protein acylation GO:0043543 42 0.249
axon midline choice point recognition GO:0016199 26 0.248
photoreceptor cell fate commitment GO:0046552 41 0.246
ribonucleoside metabolic process GO:0009119 127 0.246
regulation of catalytic activity GO:0050790 185 0.245
purine nucleoside metabolic process GO:0042278 127 0.244
glycosyl compound catabolic process GO:1901658 112 0.243
sex differentiation GO:0007548 81 0.241
Worm
positive regulation of response to external stimulus GO:0032103 44 0.239
telencephalon development GO:0021537 2 0.239
synaptic growth at neuromuscular junction GO:0051124 119 0.238
negative regulation of neural precursor cell proliferation GO:2000178 27 0.237
response to other organism GO:0051707 293 0.235
cell fate specification GO:0001708 71 0.235
digestive tract development GO:0048565 149 0.233
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.232
axon guidance GO:0007411 233 0.229
regulation of actin cytoskeleton organization GO:0032956 42 0.229
Mouse
positive regulation of cell motility GO:2000147 3 0.229
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.226
actin cytoskeleton reorganization GO:0031532 22 0.225
regulation of mitotic cell cycle GO:0007346 190 0.223
negative regulation of molecular function GO:0044092 51 0.223
cellular amine metabolic process GO:0044106 12 0.220
asymmetric stem cell division GO:0098722 49 0.220
regulation of hydrolase activity GO:0051336 97 0.219
organophosphate metabolic process GO:0019637 195 0.219
negative regulation of developmental growth GO:0048640 64 0.218
mitotic nuclear division GO:0007067 213 0.217
germ cell migration GO:0008354 43 0.216
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.216
regulation of cell size GO:0008361 63 0.216
regulation of photoreceptor cell differentiation GO:0046532 34 0.212
positive regulation of multicellular organism growth GO:0040018 21 0.212
dendrite development GO:0016358 204 0.210
positive regulation of nervous system development GO:0051962 69 0.208
response to osmotic stress GO:0006970 14 0.206
feeding behavior GO:0007631 50 0.205
axis specification GO:0009798 167 0.205
eggshell formation GO:0030703 105 0.203
regulation of transport GO:0051049 181 0.203
purine nucleoside triphosphate catabolic process GO:0009146 108 0.202
regulation of nucleotide catabolic process GO:0030811 48 0.200
negative regulation of gene expression GO:0010629 387 0.200
purine nucleoside triphosphate metabolic process GO:0009144 119 0.199
response to carbon dioxide GO:0010037 4 0.198
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.197
axon choice point recognition GO:0016198 26 0.196
larval development GO:0002164 104 0.194
Worm
anterior posterior axis specification embryo GO:0008595 103 0.194
positive regulation of nucleotide metabolic process GO:0045981 55 0.193
lipid metabolic process GO:0006629 121 0.193
positive regulation of immune response GO:0050778 63 0.187
response to endogenous stimulus GO:0009719 119 0.187
Human Mouse
intracellular transport GO:0046907 228 0.185
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.184
taxis GO:0042330 304 0.176
compound eye morphogenesis GO:0001745 249 0.175
protein transport GO:0015031 155 0.173
nucleobase containing small molecule metabolic process GO:0055086 174 0.172
striated muscle cell differentiation GO:0051146 90 0.172
development of primary sexual characteristics GO:0045137 50 0.170
Worm
negative regulation of kinase activity GO:0033673 16 0.169
signal transduction by phosphorylation GO:0023014 107 0.167
regulation of phosphatidylinositol 3 kinase activity GO:0043551 2 0.167
positive regulation of cell development GO:0010720 61 0.166
compound eye development GO:0048749 307 0.164
stem cell differentiation GO:0048863 117 0.164
protein import into nucleus GO:0006606 51 0.164
regulation of purine nucleotide catabolic process GO:0033121 48 0.164
eye photoreceptor cell fate commitment GO:0042706 37 0.163
cellular response to transforming growth factor beta stimulus GO:0071560 18 0.161
negative regulation of cell death GO:0060548 81 0.161
positive regulation of ras gtpase activity GO:0032320 36 0.160
somatic muscle development GO:0007525 66 0.160
cell fate determination GO:0001709 91 0.158
gastrulation GO:0007369 70 0.158
negative regulation of phosphorus metabolic process GO:0010563 45 0.157
positive regulation of proteolysis GO:0045862 52 0.157
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.156
humoral immune response GO:0006959 117 0.155
neuron projection extension GO:1990138 32 0.152
establishment of vesicle localization GO:0051650 51 0.150
aging GO:0007568 143 0.149
Rat Worm
membrane invagination GO:0010324 11 0.148
cellular amino acid metabolic process GO:0006520 61 0.148
r7 cell fate commitment GO:0007465 12 0.148
stem cell proliferation GO:0072089 88 0.147
negative regulation of mitotic cell cycle GO:0045930 109 0.147
ribonucleoside triphosphate catabolic process GO:0009203 108 0.146
regulation of response to extracellular stimulus GO:0032104 18 0.145
negative regulation of biosynthetic process GO:0009890 277 0.145
reproductive system development GO:0061458 74 0.144
Mouse Worm
positive regulation of cellular protein catabolic process GO:1903364 24 0.144
regulation of rho protein signal transduction GO:0035023 20 0.143
response to insulin GO:0032868 29 0.143
Human
response to peptide hormone GO:0043434 29 0.142
Human
compound eye photoreceptor development GO:0042051 78 0.142
positive regulation of catabolic process GO:0009896 105 0.142
carbohydrate derivative catabolic process GO:1901136 118 0.142
response to hydrogen peroxide GO:0042542 11 0.141
protein modification by small protein conjugation GO:0032446 79 0.141
regulation of response to wounding GO:1903034 19 0.140
positive regulation of catalytic activity GO:0043085 118 0.138
regulation of cell cycle phase transition GO:1901987 130 0.137
regulation of cell motility GO:2000145 23 0.137
imaginal disc derived wing vein specification GO:0007474 48 0.133
developmental growth involved in morphogenesis GO:0060560 65 0.133
phagocytosis engulfment GO:0006911 11 0.133
establishment of localization in cell GO:0051649 402 0.131
Worm
gland development GO:0048732 191 0.130
chemical homeostasis GO:0048878 92 0.130
positive regulation of apoptotic process GO:0043065 47 0.130
branching morphogenesis of an epithelial tube GO:0048754 45 0.130
nucleoside phosphate catabolic process GO:1901292 110 0.129
chromatin organization GO:0006325 207 0.129
regulation of macroautophagy GO:0016241 15 0.128
cellular macromolecule localization GO:0070727 220 0.128
cell adhesion GO:0007155 136 0.127
collateral sprouting GO:0048668 3 0.126
central nervous system development GO:0007417 201 0.126
macromolecular complex assembly GO:0065003 256 0.125
Yeast Mouse Rat
regulation of vesicle mediated transport GO:0060627 59 0.125
spermatogenesis GO:0007283 200 0.125
regulation of multicellular organism growth GO:0040014 40 0.124
regulation of mapk cascade GO:0043408 92 0.124
tor signaling GO:0031929 32 0.123
positive regulation of secretion GO:0051047 22 0.123
regulation of peptidyl tyrosine phosphorylation GO:0050730 10 0.122
body morphogenesis GO:0010171 2 0.122
protein complex biogenesis GO:0070271 201 0.122
Yeast Mouse Rat
myoblast fusion GO:0007520 43 0.121
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.120
regulation of anatomical structure morphogenesis GO:0022603 242 0.120
positive regulation of mitotic cell cycle GO:0045931 34 0.119
nucleotide metabolic process GO:0009117 161 0.119
cortical cytoskeleton organization GO:0030865 29 0.119
regulation of immune effector process GO:0002697 52 0.119
positive regulation of cellular catabolic process GO:0031331 95 0.119
regulation of cell division GO:0051302 72 0.119
purine nucleotide catabolic process GO:0006195 109 0.119
heart process GO:0003015 37 0.118
cortical actin cytoskeleton organization GO:0030866 24 0.117
response to oxygen containing compound GO:1901700 200 0.116
Human
embryonic development via the syncytial blastoderm GO:0001700 148 0.116
secretion by cell GO:0032940 101 0.115
Worm
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.114
adherens junction organization GO:0034332 27 0.114
cell cycle phase transition GO:0044770 140 0.112
antimicrobial humoral response GO:0019730 99 0.112
cardiovascular system development GO:0072358 82 0.112
regulation of humoral immune response GO:0002920 51 0.112
dephosphorylation GO:0016311 51 0.111
chromatin modification GO:0016568 147 0.111
regulation of proteolysis GO:0030162 87 0.110
endocytosis GO:0006897 310 0.109
Human Yeast Worm
photoreceptor cell development GO:0042461 96 0.109
nucleoside phosphate metabolic process GO:0006753 162 0.109
forebrain development GO:0030900 2 0.109
cytoplasmic transport GO:0016482 130 0.109
chorion containing eggshell formation GO:0007304 105 0.109
neuron death GO:0070997 27 0.109
regulation of neuron differentiation GO:0045664 103 0.109
regulation of cellular component biogenesis GO:0044087 201 0.108
Mouse
meiotic cell cycle process GO:1903046 132 0.108
activation of rac gtpase activity GO:0032863 3 0.108
organelle fission GO:0048285 340 0.107
blood circulation GO:0008015 26 0.107
regulation of neuron projection development GO:0010975 69 0.107
positive regulation of reactive oxygen species metabolic process GO:2000379 0 0.107
Human
gland morphogenesis GO:0022612 145 0.106
cellular carbohydrate metabolic process GO:0044262 22 0.106
digestive system development GO:0055123 149 0.106
macromolecule catabolic process GO:0009057 161 0.106
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.106
single organism cellular localization GO:1902580 180 0.105
ribonucleoside triphosphate metabolic process GO:0009199 119 0.105
single organism intracellular transport GO:1902582 207 0.104
regulation of blood circulation GO:1903522 21 0.103
multicellular organismal aging GO:0010259 140 0.101
Worm
chemosensory behavior GO:0007635 106 0.100
purine ribonucleotide metabolic process GO:0009150 145 0.100
eye development GO:0001654 323 0.100
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.099
muscle organ development GO:0007517 127 0.099
Worm
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.097
positive regulation of mapk cascade GO:0043410 63 0.097
positive regulation of programmed cell death GO:0043068 62 0.097
cellular response to abiotic stimulus GO:0071214 58 0.096
Human
regulation of stress activated mapk cascade GO:0032872 41 0.096
regulation of rho gtpase activity GO:0032319 20 0.096
syncytium formation by plasma membrane fusion GO:0000768 43 0.094
purine nucleotide metabolic process GO:0006163 146 0.094
negative regulation of epithelial cell proliferation GO:0050680 4 0.093
negative regulation of intracellular signal transduction GO:1902532 57 0.092
phagocytosis GO:0006909 215 0.092
nucleoside triphosphate catabolic process GO:0009143 108 0.092
cellular nitrogen compound catabolic process GO:0044270 165 0.091
purine ribonucleotide catabolic process GO:0009154 109 0.091
neuron fate commitment GO:0048663 50 0.091
regulation of cellular component movement GO:0051270 42 0.090
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.090
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.089
r7 cell differentiation GO:0045466 43 0.089
male gamete generation GO:0048232 201 0.089
defense response to gram negative bacterium GO:0050829 94 0.089
positive regulation of gtp catabolic process GO:0033126 43 0.089
response to biotic stimulus GO:0009607 294 0.088
germarium derived female germ line cyst formation GO:0030727 42 0.088
ribonucleotide metabolic process GO:0009259 145 0.087
mushroom body development GO:0016319 70 0.087
cellular response to endogenous stimulus GO:0071495 80 0.086
Human Mouse
regulation of erk1 and erk2 cascade GO:0070372 39 0.086
response to growth factor GO:0070848 31 0.085
Mouse
notch signaling pathway GO:0007219 120 0.085
cellular response to organic substance GO:0071310 132 0.084
Human Mouse
negative regulation of transferase activity GO:0051348 18 0.084
regionalization GO:0003002 416 0.084
transmembrane transport GO:0055085 139 0.083
establishment or maintenance of cell polarity GO:0007163 167 0.082
cell cell junction organization GO:0045216 55 0.082
glial cell migration GO:0008347 31 0.082
protein modification process GO:0036211 438 0.082
phototransduction GO:0007602 52 0.081
response to external biotic stimulus GO:0043207 293 0.080
vesicle localization GO:0051648 55 0.080
malpighian tubule development GO:0072002 64 0.080
long term memory GO:0007616 62 0.080
actin filament polymerization GO:0030041 27 0.080
Yeast Mouse
negative regulation of cell proliferation GO:0008285 69 0.079
negative regulation of cell differentiation GO:0045596 143 0.079
regulation of cellular component size GO:0032535 98 0.079
Mouse
wnt signaling pathway GO:0016055 98 0.079

drk disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.120