Drosophila melanogaster

55 known processes

SMC1 (Dmel_CG6057)

CG6057 gene product from transcript CG6057-RA

(Aliases: Dmel\CG6057,Smc1,DmSMC1,dSMC1,smc1,CG6057)

SMC1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chromosome organization GO:0051276 360 0.969
Human Yeast
neuron projection guidance GO:0097485 241 0.862
chromatin silencing GO:0006342 76 0.790
dna metabolic process GO:0006259 227 0.702
Human Yeast
sister chromatid segregation GO:0000819 92 0.606
Yeast
dendrite morphogenesis GO:0048813 199 0.601
axon guidance GO:0007411 233 0.535
chromosome segregation GO:0007059 157 0.520
Human Yeast Worm
spindle organization GO:0007051 253 0.495
gene silencing GO:0016458 138 0.488
regulation of gene expression epigenetic GO:0040029 128 0.480
negative regulation of gene expression GO:0010629 387 0.477
cell death GO:0008219 279 0.422
vesicle mediated transport GO:0016192 381 0.335
Worm
macromolecular complex assembly GO:0065003 256 0.320
protein complex assembly GO:0006461 200 0.310
negative regulation of gene expression epigenetic GO:0045814 77 0.300
chemotaxis GO:0006935 249 0.293
taxis GO:0042330 304 0.273
dendrite development GO:0016358 204 0.270
regulation of cellular catabolic process GO:0031329 157 0.267
regulation of cellular protein metabolic process GO:0032268 243 0.222
positive regulation of molecular function GO:0044093 136 0.217
eye development GO:0001654 323 0.214
axon development GO:0061564 297 0.211
organelle fission GO:0048285 340 0.210
Yeast Mouse
mitotic nuclear division GO:0007067 213 0.205
Yeast
heterochromatin organization GO:0070828 25 0.202
single organism catabolic process GO:0044712 228 0.196
positive regulation of rna biosynthetic process GO:1902680 266 0.195
mitotic cell cycle checkpoint GO:0007093 88 0.193
Human
regulation of phosphorus metabolic process GO:0051174 210 0.187
mitotic spindle organization GO:0007052 220 0.187
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.185
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.183
chromatin organization GO:0006325 207 0.181
peptidyl lysine acetylation GO:0018394 39 0.175
positive regulation of transcription dna templated GO:0045893 266 0.172
positive regulation of response to stimulus GO:0048584 323 0.168
positive regulation of nucleic acid templated transcription GO:1903508 266 0.167
mitotic cell cycle phase transition GO:0044772 138 0.166
Human
negative regulation of cell cycle phase transition GO:1901988 103 0.161
Human
death GO:0016265 284 0.156
response to reactive oxygen species GO:0000302 24 0.155
positive regulation of gene expression GO:0010628 290 0.154
regulation of cell cycle process GO:0010564 181 0.146
Human
cellular response to dna damage stimulus GO:0006974 223 0.144
Human Yeast
cell cycle phase transition GO:0044770 140 0.143
Human
telomere organization GO:0032200 21 0.143
g2 dna damage checkpoint GO:0031572 69 0.141
positive regulation of multicellular organismal process GO:0051240 143 0.138
cellular protein modification process GO:0006464 438 0.133
regulation of anatomical structure morphogenesis GO:0022603 242 0.131
telomere maintenance GO:0000723 21 0.128
mitotic sister chromatid segregation GO:0000070 87 0.120
Yeast
axonogenesis GO:0007409 290 0.120
regulation of cytoskeleton organization GO:0051493 89 0.117
regulation of cell cycle phase transition GO:1901987 130 0.114
Human
protein localization GO:0008104 284 0.113
positive regulation of catabolic process GO:0009896 105 0.111
posttranscriptional gene silencing GO:0016441 46 0.107
programmed cell death GO:0012501 257 0.105
immune system process GO:0002376 347 0.102
positive regulation of rna metabolic process GO:0051254 271 0.096
chromatin assembly GO:0031497 48 0.092
homeostatic process GO:0042592 199 0.092
negative regulation of mitotic cell cycle GO:0045930 109 0.092
Human
regulation of protein metabolic process GO:0051246 256 0.091
ras protein signal transduction GO:0007265 88 0.091
protein acetylation GO:0006473 39 0.090
catabolic process GO:0009056 409 0.086
positive regulation of macromolecule metabolic process GO:0010604 405 0.084
tissue morphogenesis GO:0048729 297 0.083
negative regulation of rna biosynthetic process GO:1902679 240 0.082
regulation of organelle organization GO:0033043 196 0.079
regulation of molecular function GO:0065009 217 0.078
growth GO:0040007 359 0.077
posttranscriptional gene silencing by rna GO:0035194 45 0.076
neural precursor cell proliferation GO:0061351 75 0.075
regulation of mitotic cell cycle phase transition GO:1901990 130 0.075
Human
embryo development ending in birth or egg hatching GO:0009792 152 0.075
Worm
response to organic substance GO:0010033 284 0.074
regulation of small gtpase mediated signal transduction GO:0051056 93 0.073
gene silencing by rna GO:0031047 57 0.073
regulation of chromosome organization GO:0033044 64 0.072
morphogenesis of an epithelium GO:0002009 276 0.072
negative regulation of nucleic acid templated transcription GO:1903507 240 0.071
regulation of phosphate metabolic process GO:0019220 210 0.070
regulation of catabolic process GO:0009894 170 0.069
purine nucleoside triphosphate metabolic process GO:0009144 119 0.067
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.066
Human
cellular response to oxygen containing compound GO:1901701 79 0.066
stem cell proliferation GO:0072089 88 0.066
regulation of apoptotic process GO:0042981 130 0.065
cellular macromolecule localization GO:0070727 220 0.065
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.064
proteolysis GO:0006508 192 0.063
response to oxygen containing compound GO:1901700 200 0.063
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.062
stem cell development GO:0048864 79 0.061
Mouse
organelle assembly GO:0070925 198 0.060
positive regulation of cellular protein metabolic process GO:0032270 118 0.059
regulation of ras protein signal transduction GO:0046578 93 0.059
protein modification by small protein conjugation or removal GO:0070647 106 0.059
establishment of localization in cell GO:0051649 402 0.057
negative regulation of cell cycle GO:0045786 116 0.056
Human
positive regulation of cellular catabolic process GO:0031331 95 0.056
organic substance catabolic process GO:1901575 308 0.055
multicellular organismal aging GO:0010259 140 0.054
imaginal disc derived leg morphogenesis GO:0007480 80 0.054
cellular component disassembly GO:0022411 46 0.053
compound eye development GO:0048749 307 0.052
protein modification process GO:0036211 438 0.052
imaginal disc fusion GO:0046528 19 0.051
negative regulation of transcription dna templated GO:0045892 237 0.051
small gtpase mediated signal transduction GO:0007264 88 0.050
response to endogenous stimulus GO:0009719 119 0.049
salivary gland development GO:0007431 162 0.048
endocytosis GO:0006897 310 0.047
Worm
heterochromatin organization involved in chromatin silencing GO:0070868 9 0.046
regulation of intracellular signal transduction GO:1902531 236 0.046
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.046
reproductive behavior GO:0019098 122 0.045
positive regulation of protein modification process GO:0031401 58 0.044
cellular catabolic process GO:0044248 372 0.044
regulation of multicellular organismal development GO:2000026 414 0.042
mitotic dna integrity checkpoint GO:0044774 75 0.042
positive regulation of developmental growth GO:0048639 62 0.042
stem cell differentiation GO:0048863 117 0.042
Mouse
peptidyl amino acid modification GO:0018193 105 0.042
meiotic cell cycle GO:0051321 171 0.041
Mouse
covalent chromatin modification GO:0016569 106 0.041
positive regulation of phosphorus metabolic process GO:0010562 139 0.041
mitotic dna damage checkpoint GO:0044773 74 0.039
regulation of protein modification process GO:0031399 112 0.039
organonitrogen compound metabolic process GO:1901564 318 0.039
regulation of programmed cell death GO:0043067 152 0.039
mitotic sister chromatid separation GO:0051306 30 0.037
transcription from rna polymerase ii promoter GO:0006366 368 0.037
regulation of cell development GO:0060284 215 0.036
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.036
cellular response to chemical stimulus GO:0070887 199 0.035
gonad development GO:0008406 50 0.035
Worm
mitotic g2 m transition checkpoint GO:0044818 70 0.035
positive regulation of cellular component organization GO:0051130 156 0.034
negative regulation of rna metabolic process GO:0051253 251 0.034
response to inorganic substance GO:0010035 44 0.034
regulation of cell death GO:0010941 173 0.034
protein transport GO:0015031 155 0.034
macromolecule catabolic process GO:0009057 161 0.033
regulation of cell differentiation GO:0045595 302 0.033
Mouse
intracellular transport GO:0046907 228 0.033
single organism intracellular transport GO:1902582 207 0.032
cellular macromolecular complex assembly GO:0034622 153 0.032
protein complex biogenesis GO:0070271 201 0.032
regulation of cell morphogenesis GO:0022604 163 0.032
regulation of catalytic activity GO:0050790 185 0.032
muscle structure development GO:0061061 224 0.031
cellular protein localization GO:0034613 160 0.031
positive regulation of cellular component biogenesis GO:0044089 80 0.031
single organism behavior GO:0044708 391 0.030
nuclear division GO:0000280 332 0.030
Yeast Mouse
metaphase anaphase transition of cell cycle GO:0044784 28 0.030
nucleotide metabolic process GO:0009117 161 0.030
central nervous system development GO:0007417 201 0.030
glycosyl compound metabolic process GO:1901657 127 0.030
cellular response to organic substance GO:0071310 132 0.029
positive regulation of developmental process GO:0051094 143 0.029
regulation of cell cycle GO:0051726 291 0.029
Human
purine nucleoside monophosphate metabolic process GO:0009126 50 0.029
regulation of mitotic sister chromatid separation GO:0010965 28 0.029
ribose phosphate metabolic process GO:0019693 145 0.029
modification dependent protein catabolic process GO:0019941 78 0.028
cell proliferation GO:0008283 299 0.028
response to external biotic stimulus GO:0043207 293 0.028
regulation of cellular localization GO:0060341 136 0.027
positive regulation of programmed cell death GO:0043068 62 0.026
small molecule metabolic process GO:0044281 305 0.026
positive regulation of phosphate metabolic process GO:0045937 139 0.026
purine nucleotide metabolic process GO:0006163 146 0.026
regulation of hydrolase activity GO:0051336 97 0.026
germarium derived egg chamber formation GO:0007293 101 0.026
meiotic dna double strand break formation GO:0042138 1 0.026
heterocycle catabolic process GO:0046700 166 0.026
positive regulation of phosphorylation GO:0042327 87 0.026
regulation of mitotic cell cycle GO:0007346 190 0.026
Human
apoptotic process GO:0006915 159 0.026
establishment of protein localization to organelle GO:0072594 62 0.025
stem cell division GO:0017145 69 0.025
positive regulation of hydrolase activity GO:0051345 78 0.025
atp metabolic process GO:0046034 49 0.025
eye photoreceptor cell development GO:0042462 81 0.025
protein ubiquitination GO:0016567 70 0.025
regulation of transcription by chromatin organization GO:0034401 3 0.025
regulation of response to stress GO:0080134 200 0.025
regulation of neurogenesis GO:0050767 158 0.025
aging GO:0007568 143 0.024
regulation of phosphorylation GO:0042325 147 0.024
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.024
Human
metaphase anaphase transition of mitotic cell cycle GO:0007091 28 0.024
body morphogenesis GO:0010171 2 0.023
proteasomal protein catabolic process GO:0010498 59 0.023
female germ line cyst formation GO:0048135 42 0.023
multi organism reproductive behavior GO:0044705 121 0.022
regulation of nuclear division GO:0051783 58 0.022
positive regulation of signal transduction GO:0009967 223 0.022
nucleoside triphosphate metabolic process GO:0009141 120 0.022
larval development GO:0002164 104 0.022
Worm
sensory organ morphogenesis GO:0090596 260 0.022
phosphorylation GO:0016310 294 0.022
regulation of mitotic sister chromatid segregation GO:0033047 28 0.022
protein catabolic process GO:0030163 101 0.022
wing disc morphogenesis GO:0007472 344 0.021
nucleobase containing small molecule metabolic process GO:0055086 174 0.021
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.021
organophosphate metabolic process GO:0019637 195 0.021
regulation of proteolysis GO:0030162 87 0.021
organic substance transport GO:0071702 257 0.021
positive regulation of organelle organization GO:0010638 65 0.021
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.021
purine containing compound metabolic process GO:0072521 155 0.021
actin cytoskeleton organization GO:0030036 206 0.020
purine containing compound catabolic process GO:0072523 112 0.020
regulation of establishment of protein localization GO:0070201 61 0.020
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.020
regulation of sister chromatid segregation GO:0033045 28 0.020
photoreceptor cell development GO:0042461 96 0.020
organic cyclic compound catabolic process GO:1901361 168 0.019
regulation of actin filament based process GO:0032970 42 0.019
ribonucleoside triphosphate metabolic process GO:0009199 119 0.019
germarium derived female germ line cyst formation GO:0030727 42 0.019
signal transduction in response to dna damage GO:0042770 3 0.019
Human
centrosome organization GO:0051297 163 0.019
regulation of proteasomal protein catabolic process GO:0061136 39 0.019
negative regulation of cell cycle process GO:0010948 109 0.018
Human
regulation of localization GO:0032879 275 0.018
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 30 0.018
ribonucleotide catabolic process GO:0009261 109 0.018
camera type eye development GO:0043010 4 0.018
rna localization GO:0006403 115 0.018
negative regulation of programmed cell death GO:0043069 72 0.018
aromatic compound catabolic process GO:0019439 166 0.018
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.018
Human
regulation of chromosome segregation GO:0051983 32 0.017
karyosome formation GO:0030717 22 0.017
dorsal ventral pattern formation GO:0009953 133 0.017
internal peptidyl lysine acetylation GO:0018393 38 0.017
regulation of meiosis GO:0040020 3 0.017
mitotic g2 dna damage checkpoint GO:0007095 69 0.017
chromosome condensation GO:0030261 41 0.017
cellular protein catabolic process GO:0044257 83 0.017
embryonic morphogenesis GO:0048598 206 0.017
neurological system process GO:0050877 358 0.016
embryonic development via the syncytial blastoderm GO:0001700 148 0.016
cell division GO:0051301 248 0.016
exocrine system development GO:0035272 162 0.016
defense response to other organism GO:0098542 225 0.016
dna conformation change GO:0071103 105 0.016
posttranscriptional regulation of gene expression GO:0010608 145 0.016
positive regulation of biosynthetic process GO:0009891 316 0.016
meiotic cell cycle process GO:1903046 132 0.016
internal protein amino acid acetylation GO:0006475 38 0.016
cellular nitrogen compound catabolic process GO:0044270 165 0.016
purine ribonucleoside metabolic process GO:0046128 127 0.015
establishment of protein localization GO:0045184 163 0.015
negative regulation of cell division GO:0051782 17 0.015
meiotic nuclear division GO:0007126 151 0.015
Mouse
regulation of cellular amine metabolic process GO:0033238 3 0.015
cellular protein complex assembly GO:0043623 71 0.015
negative regulation of signal transduction by p53 class mediator GO:1901797 1 0.015
developmental programmed cell death GO:0010623 138 0.015
ncrna metabolic process GO:0034660 43 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.015
signal transduction by phosphorylation GO:0023014 107 0.015
mrna metabolic process GO:0016071 124 0.015
response to abiotic stimulus GO:0009628 341 0.015
Human Worm
response to biotic stimulus GO:0009607 294 0.015
protein phosphorylation GO:0006468 169 0.015
chromosome separation GO:0051304 42 0.014
appendage morphogenesis GO:0035107 397 0.014
oocyte differentiation GO:0009994 145 0.014
embryonic organ development GO:0048568 50 0.014
negative regulation of developmental process GO:0051093 201 0.014
Mouse
protein localization to organelle GO:0033365 82 0.014
spinal cord development GO:0021510 1 0.014
heart development GO:0007507 82 0.014
negative regulation of apoptotic process GO:0043066 63 0.014
ubiquitin dependent protein catabolic process GO:0006511 78 0.014
peptidyl lysine modification GO:0018205 57 0.014
positive regulation of intracellular signal transduction GO:1902533 116 0.014
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.014
chaeta development GO:0022416 97 0.014
protein dna complex subunit organization GO:0071824 86 0.014
response to nitrogen compound GO:1901698 90 0.014
carbohydrate derivative metabolic process GO:1901135 217 0.014
prostaglandin biosynthetic process GO:0001516 1 0.013
phagocytosis GO:0006909 215 0.013
cytoplasmic transport GO:0016482 130 0.013
actin filament based process GO:0030029 220 0.013
circulatory system development GO:0072359 82 0.013
synapse organization GO:0050808 196 0.013
cell fate determination GO:0001709 91 0.013
modification dependent macromolecule catabolic process GO:0043632 79 0.013
cell migration GO:0016477 238 0.013
immune response GO:0006955 246 0.013
nucleus localization GO:0051647 34 0.013
multi organism behavior GO:0051705 175 0.013
cellular response to organic cyclic compound GO:0071407 32 0.013
segmentation GO:0035282 207 0.013
microtubule organizing center organization GO:0031023 168 0.013
organophosphate catabolic process GO:0046434 112 0.013
regulation of cellular response to stress GO:0080135 89 0.013
nucleotide catabolic process GO:0009166 109 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.012
positive regulation of protein metabolic process GO:0051247 128 0.012
positive regulation of cell death GO:0010942 69 0.012
locomotory behavior GO:0007626 176 0.012
brain development GO:0007420 120 0.012
regulation of transport GO:0051049 181 0.012
regulation of growth GO:0040008 233 0.012
regulation of organ morphogenesis GO:2000027 78 0.012
regulation of neuron differentiation GO:0045664 103 0.012
positive regulation of gliogenesis GO:0014015 5 0.012
cellular macromolecule catabolic process GO:0044265 136 0.012
dna methylation or demethylation GO:0044728 4 0.012
purine ribonucleoside catabolic process GO:0046130 112 0.012
nucleoside triphosphate catabolic process GO:0009143 108 0.012
regulation of chitin based cuticle tanning GO:0007564 14 0.012
regulation of cell projection organization GO:0031344 92 0.012
regulation of microtubule cytoskeleton organization GO:0070507 41 0.012
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 1 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.012
anatomical structure homeostasis GO:0060249 97 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.012
Human
dna repair GO:0006281 54 0.012
Yeast
dna damage checkpoint GO:0000077 78 0.011
organonitrogen compound catabolic process GO:1901565 128 0.011
innate immune response GO:0045087 144 0.011
positive regulation of cell differentiation GO:0045597 64 0.011
germ line cyst formation GO:0048134 44 0.011
regulation of dna metabolic process GO:0051052 34 0.011
Human
purine nucleotide catabolic process GO:0006195 109 0.011
centrosome cycle GO:0007098 137 0.011
retina morphogenesis in camera type eye GO:0060042 2 0.011
negative regulation of cellular metabolic process GO:0031324 382 0.011
Human
regulation of nervous system development GO:0051960 248 0.011
nucleosome mobilization GO:0042766 9 0.011
regulation of mitosis GO:0007088 56 0.011
autophagy GO:0006914 108 0.011
receptor mediated endocytosis GO:0006898 21 0.010
Worm
nucleoside metabolic process GO:0009116 127 0.010
regulation of protein catabolic process GO:0042176 55 0.010
dephosphorylation GO:0016311 51 0.010
tissue death GO:0016271 102 0.010
meiosis i GO:0007127 59 0.010
regulation of microtubule based process GO:0032886 49 0.010

SMC1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org