Drosophila melanogaster

99 known processes

rt (Dmel_CG6097)

rotated abdomen

(Aliases: pomt,Dmel\CG6097,Rot_abd,fs(3)neo1,DPOMT1,CG6097,dPOMT1,POMT1)

rt biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chitin based cuticle sclerotization GO:0007593 19 0.733
adult chitin containing cuticle pigmentation GO:0048085 16 0.438
molting cycle chitin based cuticle GO:0007591 56 0.430
muscle attachment GO:0016203 36 0.366
cuticle pigmentation GO:0048067 22 0.189
cellular component assembly involved in morphogenesis GO:0010927 151 0.177
carbohydrate derivative biosynthetic process GO:1901137 85 0.157
cuticle development GO:0042335 86 0.148
notch signaling pathway GO:0007219 120 0.136
regionalization GO:0003002 416 0.133
regulation of multicellular organismal development GO:2000026 414 0.130
positive regulation of macromolecule metabolic process GO:0010604 405 0.130
regulation of adult chitin containing cuticle pigmentation GO:0048082 13 0.123
organonitrogen compound metabolic process GO:1901564 318 0.120
intracellular transport GO:0046907 228 0.117
cellular protein modification process GO:0006464 438 0.113
dendrite morphogenesis GO:0048813 199 0.109
positive regulation of cell communication GO:0010647 250 0.106
regulation of anatomical structure morphogenesis GO:0022603 242 0.104
protein modification process GO:0036211 438 0.103
negative regulation of response to stimulus GO:0048585 258 0.100
inorganic cation transmembrane transport GO:0098662 61 0.094
immune response regulating signaling pathway GO:0002764 2 0.092
transcription from rna polymerase ii promoter GO:0006366 368 0.090
intracellular signal transduction GO:0035556 300 0.089
single organism intracellular transport GO:1902582 207 0.086
phenol containing compound biosynthetic process GO:0046189 6 0.084
sarcomere organization GO:0045214 26 0.079
post embryonic appendage morphogenesis GO:0035120 385 0.078
actin cytoskeleton organization GO:0030036 206 0.078
positive regulation of nucleic acid templated transcription GO:1903508 266 0.077
pigmentation GO:0043473 75 0.077
muscle cell differentiation GO:0042692 103 0.073
connective tissue development GO:0061448 3 0.071
activation of innate immune response GO:0002218 4 0.070
molting cycle process GO:0022404 29 0.069
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.069
extracellular matrix organization GO:0030198 32 0.068
Mouse
synaptic growth at neuromuscular junction GO:0051124 119 0.065
imaginal disc derived appendage morphogenesis GO:0035114 395 0.065
cell motility GO:0048870 251 0.065
extracellular structure organization GO:0043062 46 0.064
Mouse
molting cycle GO:0042303 56 0.064
sensory organ morphogenesis GO:0090596 260 0.063
somatic muscle development GO:0007525 66 0.062
regulation of notch signaling pathway GO:0008593 100 0.061
synapse assembly GO:0007416 143 0.060
transmembrane transport GO:0055085 139 0.060
negative regulation of gene expression GO:0010629 387 0.059
developmental pigmentation GO:0048066 68 0.059
lipid modification GO:0030258 24 0.059
regulation of chitin based cuticle tanning GO:0007564 14 0.058
appendage development GO:0048736 401 0.057
innate immune response activating signal transduction GO:0002758 2 0.056
myofibril assembly GO:0030239 36 0.056
imaginal disc derived appendage development GO:0048737 399 0.056
regulation of developmental pigmentation GO:0048070 24 0.056
positive regulation of gene expression GO:0010628 290 0.054
substrate adhesion dependent cell spreading GO:0034446 2 0.054
glycoprotein biosynthetic process GO:0009101 41 0.053
synapse organization GO:0050808 196 0.053
adult behavior GO:0030534 137 0.053
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.052
organelle assembly GO:0070925 198 0.052
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.052
outflow tract morphogenesis GO:0003151 4 0.051
muscle structure development GO:0061061 224 0.051
positive regulation of cellular biosynthetic process GO:0031328 316 0.050
positive regulation of response to stimulus GO:0048584 323 0.050
regulation of response to stress GO:0080134 200 0.049
circulatory system development GO:0072359 82 0.049
cell proliferation GO:0008283 299 0.048
regulation of developmental growth GO:0048638 174 0.048
cytoplasmic transport GO:0016482 130 0.048
negative regulation of cellular metabolic process GO:0031324 382 0.047
dendrite development GO:0016358 204 0.046
anion homeostasis GO:0055081 3 0.046
negative regulation of biosynthetic process GO:0009890 277 0.045
anatomical structure homeostasis GO:0060249 97 0.045
cellular amino acid metabolic process GO:0006520 61 0.044
localization of cell GO:0051674 257 0.044
protein phosphorylation GO:0006468 169 0.043
kidney morphogenesis GO:0060993 3 0.043
negative regulation of signal transduction GO:0009968 206 0.043
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.042
response to oxidative stress GO:0006979 86 0.042
protein localization GO:0008104 284 0.041
nephron epithelium morphogenesis GO:0072088 3 0.041
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.041
morphogenesis of an epithelium GO:0002009 276 0.041
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.040
skeletal muscle organ development GO:0060538 48 0.039
negative regulation of rna metabolic process GO:0051253 251 0.039
neuromuscular junction development GO:0007528 149 0.039
multicellular organismal homeostasis GO:0048871 41 0.038
negative regulation of signaling GO:0023057 219 0.038
circadian rhythm GO:0007623 105 0.037
cell death GO:0008219 279 0.037
positive regulation of signaling GO:0023056 243 0.037
positive regulation of signal transduction GO:0009967 223 0.036
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.036
stress activated protein kinase signaling cascade GO:0031098 55 0.036
positive regulation of phosphate metabolic process GO:0045937 139 0.036
immune response activating signal transduction GO:0002757 2 0.036
regulation of cell death GO:0010941 173 0.035
organic substance catabolic process GO:1901575 308 0.035
cell migration GO:0016477 238 0.035
camera type eye development GO:0043010 4 0.035
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.035
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.035
positive regulation of dendrite morphogenesis GO:0050775 9 0.035
actin filament based process GO:0030029 220 0.034
imaginal disc derived wing morphogenesis GO:0007476 337 0.034
neuron projection guidance GO:0097485 241 0.034
epithelial cell differentiation GO:0030855 322 0.034
regulation of epithelial cell proliferation GO:0050678 4 0.033
muscle cell development GO:0055001 50 0.033
establishment of localization in cell GO:0051649 402 0.032
positive regulation of rna metabolic process GO:0051254 271 0.032
cellular pigmentation GO:0033059 12 0.032
response to oxygen containing compound GO:1901700 200 0.032
positive regulation of transcription dna templated GO:0045893 266 0.032
developmental growth GO:0048589 280 0.031
kidney epithelium development GO:0072073 3 0.031
muscle organ development GO:0007517 127 0.031
establishment or maintenance of cell polarity GO:0007163 167 0.031
regulation of cellular response to stress GO:0080135 89 0.031
wing disc morphogenesis GO:0007472 344 0.030
appendage morphogenesis GO:0035107 397 0.030
lipid metabolic process GO:0006629 121 0.030
phosphorylation GO:0016310 294 0.030
catechol containing compound biosynthetic process GO:0009713 3 0.030
response to organic substance GO:0010033 284 0.029
chemotaxis GO:0006935 249 0.029
mitotic nuclear division GO:0007067 213 0.029
cellular catabolic process GO:0044248 372 0.028
pattern recognition receptor signaling pathway GO:0002221 2 0.028
regulation of synapse structure and activity GO:0050803 128 0.028
stress activated mapk cascade GO:0051403 52 0.028
regulation of hydrolase activity GO:0051336 97 0.028
response to nitrogen compound GO:1901698 90 0.028
positive regulation of catabolic process GO:0009896 105 0.027
respiratory system development GO:0060541 213 0.027
positive regulation of intracellular signal transduction GO:1902533 116 0.027
ovarian nurse cell to oocyte transport GO:0007300 27 0.027
gene silencing GO:0016458 138 0.027
nephron tubule development GO:0072080 3 0.027
regulation of phosphate metabolic process GO:0019220 210 0.026
developmental maturation GO:0021700 172 0.026
ribose phosphate metabolic process GO:0019693 145 0.026
dopamine metabolic process GO:0042417 7 0.026
oxoacid metabolic process GO:0043436 103 0.026
small molecule metabolic process GO:0044281 305 0.026
amine metabolic process GO:0009308 12 0.026
regulation of cell differentiation GO:0045595 302 0.026
wnt signaling pathway GO:0016055 98 0.026
regulation of protein metabolic process GO:0051246 256 0.025
response to organophosphorus GO:0046683 2 0.025
purine nucleotide metabolic process GO:0006163 146 0.025
positive regulation of cellular protein metabolic process GO:0032270 118 0.025
organophosphate metabolic process GO:0019637 195 0.025
regulation of response to oxidative stress GO:1902882 4 0.025
response to reactive oxygen species GO:0000302 24 0.024
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 4 0.024
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.024
apoptotic process GO:0006915 159 0.024
negative regulation of notch signaling pathway GO:0045746 41 0.024
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.024
cellular response to endogenous stimulus GO:0071495 80 0.024
regulation of protein localization GO:0032880 76 0.024
embryonic organ development GO:0048568 50 0.024
single organismal cell cell adhesion GO:0016337 45 0.024
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.024
camera type eye morphogenesis GO:0048593 2 0.023
chaeta development GO:0022416 97 0.023
multicellular organismal aging GO:0010259 140 0.023
single organism biosynthetic process GO:0044711 206 0.023
regulation of cellular protein metabolic process GO:0032268 243 0.023
positive regulation of developmental process GO:0051094 143 0.022
nephron development GO:0072006 3 0.022
positive regulation of biosynthetic process GO:0009891 316 0.022
cellular macromolecule localization GO:0070727 220 0.022
regulation of cellular response to oxidative stress GO:1900407 4 0.022
tissue morphogenesis GO:0048729 297 0.022
regulation of autophagy GO:0010506 62 0.022
actomyosin structure organization GO:0031032 56 0.022
positive regulation of cellular catabolic process GO:0031331 95 0.021
posttranscriptional regulation of gene expression GO:0010608 145 0.021
carbohydrate derivative metabolic process GO:1901135 217 0.021
positive regulation of cell motility GO:2000147 3 0.021
positive regulation of phosphorus metabolic process GO:0010562 139 0.021
regulation of organ morphogenesis GO:2000027 78 0.021
axon guidance GO:0007411 233 0.021
epithelial cell development GO:0002064 274 0.021
biological adhesion GO:0022610 138 0.021
negative regulation of cell communication GO:0010648 223 0.021
positive regulation of synapse assembly GO:0051965 29 0.021
ion transmembrane transport GO:0034220 122 0.021
actin filament organization GO:0007015 126 0.020
extrinsic apoptotic signaling pathway GO:0097191 1 0.020
negative regulation of nucleic acid templated transcription GO:1903507 240 0.020
regulation of localization GO:0032879 275 0.020
protein modification by small protein conjugation or removal GO:0070647 106 0.020
signal transduction by phosphorylation GO:0023014 107 0.020
chromatin silencing GO:0006342 76 0.020
stem cell proliferation GO:0072089 88 0.019
morphogenesis of a branching structure GO:0001763 45 0.019
open tracheal system development GO:0007424 204 0.019
vesicle mediated transport GO:0016192 381 0.019
cellular response to molecule of bacterial origin GO:0071219 3 0.019
cellular response to organic substance GO:0071310 132 0.019
positive regulation of rna biosynthetic process GO:1902680 266 0.019
carboxylic acid metabolic process GO:0019752 92 0.019
organic acid metabolic process GO:0006082 103 0.018
response to abiotic stimulus GO:0009628 341 0.018
axonogenesis GO:0007409 290 0.018
chemical homeostasis GO:0048878 92 0.018
regulation of protein transport GO:0051223 57 0.018
response to wounding GO:0009611 94 0.018
single organism catabolic process GO:0044712 228 0.018
regulation of cellular localization GO:0060341 136 0.018
limb development GO:0060173 1 0.018
homeostatic process GO:0042592 199 0.018
negative regulation of cellular response to oxidative stress GO:1900408 1 0.018
embryonic morphogenesis GO:0048598 206 0.018
growth GO:0040007 359 0.017
nephron tubule morphogenesis GO:0072078 3 0.017
nucleotide metabolic process GO:0009117 161 0.017
myotube cell development GO:0014904 3 0.017
response to lipopolysaccharide GO:0032496 4 0.017
regulation of cell proliferation GO:0042127 163 0.017
death GO:0016265 284 0.017
regulation of catabolic process GO:0009894 170 0.017
heterocycle catabolic process GO:0046700 166 0.017
regulation of phosphorus metabolic process GO:0051174 210 0.017
regulation of cellular component biogenesis GO:0044087 201 0.017
columnar cuboidal epithelial cell development GO:0002066 249 0.017
rna localization GO:0006403 115 0.017
membrane organization GO:0061024 112 0.017
embryo development ending in birth or egg hatching GO:0009792 152 0.016
aging GO:0007568 143 0.016
regulation of cellular amine metabolic process GO:0033238 3 0.016
catabolic process GO:0009056 409 0.016
regulation of synapse organization GO:0050807 110 0.016
salivary gland development GO:0007431 162 0.016
protein secretion GO:0009306 45 0.016
body morphogenesis GO:0010171 2 0.016
organic substance transport GO:0071702 257 0.016
cell aging GO:0007569 2 0.016
kidney development GO:0001822 3 0.016
mapk cascade GO:0000165 107 0.016
regulation of synapse assembly GO:0051963 94 0.016
eye development GO:0001654 323 0.016
compound eye development GO:0048749 307 0.016
response to bacterium GO:0009617 198 0.015
protein transport GO:0015031 155 0.015
striated muscle cell development GO:0055002 50 0.015
purine containing compound metabolic process GO:0072521 155 0.015
ovarian follicle cell development GO:0030707 248 0.015
programmed cell death GO:0012501 257 0.015
positive regulation of programmed cell death GO:0043068 62 0.015
phagocytosis GO:0006909 215 0.015
organonitrogen compound catabolic process GO:1901565 128 0.015
defense response GO:0006952 300 0.015
positive regulation of mapk cascade GO:0043410 63 0.015
pigment metabolic process GO:0042440 84 0.015
neuron death GO:0070997 27 0.015
nucleoside catabolic process GO:0009164 112 0.015
positive regulation of multicellular organismal process GO:0051240 143 0.015
organophosphate biosynthetic process GO:0090407 46 0.015
regulation of cellular catabolic process GO:0031329 157 0.015
single organism cell adhesion GO:0098602 47 0.015
epithelial cell migration GO:0010631 148 0.014
cellular response to chemical stimulus GO:0070887 199 0.014
response to extracellular stimulus GO:0009991 116 0.014
regulation of cellular ketone metabolic process GO:0010565 3 0.014
ribonucleotide metabolic process GO:0009259 145 0.014
regulation of mapk cascade GO:0043408 92 0.014
regulation of intracellular signal transduction GO:1902531 236 0.014
ribonucleoside metabolic process GO:0009119 127 0.014
macromolecular complex assembly GO:0065003 256 0.014
compound eye morphogenesis GO:0001745 249 0.014
tissue homeostasis GO:0001894 36 0.014
carbohydrate metabolic process GO:0005975 82 0.014
nucleobase containing small molecule metabolic process GO:0055086 174 0.014
response to oxygen levels GO:0070482 59 0.014
formation of anatomical boundary GO:0048859 37 0.014
carbohydrate derivative catabolic process GO:1901136 118 0.014
regulation of transport GO:0051049 181 0.014
immune system process GO:0002376 347 0.014
regulation of neuron death GO:1901214 26 0.013
nucleoside phosphate metabolic process GO:0006753 162 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.013
embryonic pattern specification GO:0009880 174 0.013
mucosal immune response GO:0002385 10 0.013
apoptotic process involved in morphogenesis GO:0060561 3 0.013
humoral immune response GO:0006959 117 0.013
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.013
establishment of cell polarity GO:0030010 40 0.013
negative regulation of gene expression epigenetic GO:0045814 77 0.013
regulation of immune system process GO:0002682 176 0.013
sensory perception GO:0007600 196 0.013
cell division GO:0051301 248 0.013
response to other organism GO:0051707 293 0.013
negative regulation of cellular biosynthetic process GO:0031327 277 0.013
organelle localization GO:0051640 148 0.013
maintenance of location GO:0051235 73 0.013
regulation of wnt signaling pathway GO:0030111 68 0.013
morphogenesis of a polarized epithelium GO:0001738 93 0.013
membrane depolarization GO:0051899 4 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.013
organonitrogen compound biosynthetic process GO:1901566 117 0.012
endocytosis GO:0006897 310 0.012
positive regulation of cell migration GO:0030335 2 0.012
cellular amine metabolic process GO:0044106 12 0.012
protein glycosylation GO:0006486 32 0.012
purine ribonucleoside metabolic process GO:0046128 127 0.012
purine ribonucleotide metabolic process GO:0009150 145 0.012
cell adhesion GO:0007155 136 0.012
positive regulation of apoptotic signaling pathway GO:2001235 4 0.012
nitrogen compound transport GO:0071705 85 0.012
rna processing GO:0006396 147 0.012
ethanolamine containing compound metabolic process GO:0042439 4 0.012
response to decreased oxygen levels GO:0036293 58 0.012
necrotic cell death GO:0070265 1 0.012
response to hypoxia GO:0001666 53 0.012
alpha amino acid metabolic process GO:1901605 20 0.012
secretion by cell GO:0032940 101 0.012
negative regulation of cellular protein metabolic process GO:0032269 85 0.012
purine nucleoside triphosphate metabolic process GO:0009144 119 0.012
epithelial cell proliferation GO:0050673 15 0.012
defense response to gram negative bacterium GO:0050829 94 0.011
positive regulation of molecular function GO:0044093 136 0.011
regulation of tube length open tracheal system GO:0035159 24 0.011
cellular response to oxidative stress GO:0034599 28 0.011
response to heat GO:0009408 63 0.011
ameboidal type cell migration GO:0001667 151 0.011
positive regulation of catalytic activity GO:0043085 118 0.011
morphogenesis of embryonic epithelium GO:0016331 94 0.011
cell fate determination GO:0001709 91 0.011
purine nucleoside metabolic process GO:0042278 127 0.011
cellular response to organic cyclic compound GO:0071407 32 0.011
nephron epithelium development GO:0072009 3 0.011
regulation of response to external stimulus GO:0032101 115 0.011
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.011
nucleoside metabolic process GO:0009116 127 0.011
positive regulation of wnt signaling pathway GO:0030177 25 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
reproductive behavior GO:0019098 122 0.011
cellular response to lipopolysaccharide GO:0071222 3 0.011
negative regulation of protein metabolic process GO:0051248 85 0.011
positive regulation of cell death GO:0010942 69 0.011
determination of adult lifespan GO:0008340 137 0.011
spermatogenesis GO:0007283 200 0.011
cytoskeleton dependent intracellular transport GO:0030705 44 0.011
regulation of stress activated mapk cascade GO:0032872 41 0.011
establishment of organelle localization GO:0051656 122 0.011
response to endogenous stimulus GO:0009719 119 0.011
regulation of cell substrate adhesion GO:0010810 2 0.010
regulation of phosphatase activity GO:0010921 3 0.010
autophagy GO:0006914 108 0.010
immune response GO:0006955 246 0.010
skeletal muscle fiber development GO:0048741 3 0.010
regulation of apoptotic process GO:0042981 130 0.010
glycosyl compound metabolic process GO:1901657 127 0.010
macromolecule catabolic process GO:0009057 161 0.010
neuron apoptotic process GO:0051402 17 0.010
reactive oxygen species metabolic process GO:0072593 22 0.010
response to organonitrogen compound GO:0010243 75 0.010
positive regulation of transport GO:0051050 92 0.010
secretion GO:0046903 109 0.010
tube development GO:0035295 244 0.010
branching morphogenesis of an epithelial tube GO:0048754 45 0.010
regulation of dendrite development GO:0050773 37 0.010
striated muscle cell differentiation GO:0051146 90 0.010
inorganic ion transmembrane transport GO:0098660 73 0.010
regulation of cell development GO:0060284 215 0.010
adult locomotory behavior GO:0008344 76 0.010

rt disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.053
disease of metabolism DOID:0014667 0 0.031
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016
nervous system disease DOID:863 0 0.014
inherited metabolic disorder DOID:655 0 0.013
cardiovascular system disease DOID:1287 0 0.011
hair disease DOID:421 0 0.011
integumentary system disease DOID:16 0 0.011