Drosophila melanogaster

274 known processes

aub (Dmel_CG6137)

aubergine

(Aliases: Aub,CG6137,Dmel\CG6137,sti,sting,AUB,ms(2)32D)

aub biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
germarium derived egg chamber formation GO:0007293 101 0.965
meiotic cell cycle process GO:1903046 132 0.900
Mouse
pirna metabolic process GO:0034587 10 0.899
Zebrafish Mouse
posttranscriptional gene silencing by rna GO:0035194 45 0.761
meiotic cell cycle GO:0051321 171 0.744
Zebrafish Mouse
organelle fission GO:0048285 340 0.742
positive regulation of mrna metabolic process GO:1903313 5 0.723
negative regulation of gene expression GO:0010629 387 0.709
gene silencing by rna GO:0031047 57 0.688
oocyte anterior posterior axis specification GO:0007314 72 0.661
oocyte differentiation GO:0009994 145 0.634
negative regulation of transposition GO:0010529 12 0.618
negative regulation of cellular metabolic process GO:0031324 382 0.612
regulation of transposition GO:0010528 13 0.612
regionalization GO:0003002 416 0.608
meiotic nuclear division GO:0007126 151 0.592
Zebrafish Mouse
positive regulation of mrna catabolic process GO:0061014 5 0.589
gene silencing GO:0016458 138 0.584
dorsal appendage formation GO:0046843 47 0.575
oocyte maturation GO:0001556 3 0.553
embryonic pattern specification GO:0009880 174 0.545
spermatogenesis GO:0007283 200 0.545
Mouse Fly
pole plasm assembly GO:0007315 61 0.527
positive regulation of nuclear transcribed mrna poly a tail shortening GO:0060213 4 0.519
regulation of gene expression epigenetic GO:0040029 128 0.492
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.491
regulation of cell differentiation GO:0045595 302 0.480
targeting of mrna for destruction involved in rna interference GO:0030423 4 0.452
positive regulation of gene expression GO:0010628 290 0.447
transposition GO:0032196 13 0.438
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.417
karyosome formation GO:0030717 22 0.415
oocyte development GO:0048599 124 0.405
ncrna metabolic process GO:0034660 43 0.395
Zebrafish Mouse
intracellular mrna localization GO:0008298 66 0.385
eggshell formation GO:0030703 105 0.365
pole plasm protein localization GO:0007318 10 0.364
chorion containing eggshell formation GO:0007304 105 0.354
epithelial cell development GO:0002064 274 0.351
mrna metabolic process GO:0016071 124 0.348
negative regulation of rna biosynthetic process GO:1902679 240 0.347
germarium derived oocyte fate determination GO:0007294 26 0.338
negative regulation of nucleic acid templated transcription GO:1903507 240 0.325
negative regulation of cellular biosynthetic process GO:0031327 277 0.322
ribonucleoprotein complex subunit organization GO:0071826 28 0.321
anterior posterior axis specification GO:0009948 109 0.318
positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay GO:1900153 4 0.306
germ line stem cell division GO:0042078 25 0.297
Fly
regulation of cell development GO:0060284 215 0.295
regulation of reproductive process GO:2000241 54 0.292
regulation of multicellular organismal development GO:2000026 414 0.283
rna interference GO:0016246 27 0.282
regulation of pole plasm oskar mrna localization GO:0007317 27 0.276
regulation of oocyte development GO:0060281 27 0.271
cellular nitrogen compound catabolic process GO:0044270 165 0.242
posttranscriptional gene silencing GO:0016441 46 0.241
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.240
negative regulation of biosynthetic process GO:0009890 277 0.239
anterior posterior pattern specification GO:0009952 136 0.235
positive regulation of cellular catabolic process GO:0031331 95 0.235
male gamete generation GO:0048232 201 0.233
Mouse Fly
oocyte axis specification GO:0007309 108 0.231
nuclear transcribed mrna catabolic process deadenylation dependent decay GO:0000288 14 0.222
nuclear division GO:0000280 332 0.212
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.204
negative regulation of rna metabolic process GO:0051253 251 0.198
stem cell development GO:0048864 79 0.198
Zebrafish Mouse Fly
regulation of multi organism process GO:0043900 131 0.183
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.177
rna catabolic process GO:0006401 37 0.176
positive regulation of rna metabolic process GO:0051254 271 0.172
columnar cuboidal epithelial cell development GO:0002066 249 0.168
positive regulation of macromolecule metabolic process GO:0010604 405 0.167
transcription from rna polymerase ii promoter GO:0006366 368 0.167
nuclear transcribed mrna catabolic process GO:0000956 24 0.165
negative regulation of developmental process GO:0051093 201 0.163
Zebrafish Mouse Fly
female germ line cyst formation GO:0048135 42 0.152
oocyte nucleus localization involved in oocyte dorsal ventral axis specification GO:0051663 12 0.152
posttranscriptional regulation of gene expression GO:0010608 145 0.151
cell division GO:0051301 248 0.147
Mouse Fly
regulation of meiosis GO:0040020 3 0.146
Mouse
segmentation GO:0035282 207 0.145
rna localization GO:0006403 115 0.138
negative regulation of cell differentiation GO:0045596 143 0.137
Zebrafish Mouse Fly
cell maturation GO:0048469 144 0.126
organic substance catabolic process GO:1901575 308 0.124
pronuclear migration GO:0035046 4 0.120
eggshell chorion assembly GO:0007306 66 0.115
oocyte construction GO:0007308 112 0.112
regulation of cell maturation GO:1903429 27 0.105
dna conformation change GO:0071103 105 0.103
germ line cyst formation GO:0048134 44 0.102
axis specification GO:0009798 167 0.101
mrna catabolic process GO:0006402 33 0.101
female germ line stem cell asymmetric division GO:0048132 14 0.100
Fly
male meiosis GO:0007140 52 0.099
germarium derived female germ line cyst formation GO:0030727 42 0.099
positive regulation of response to stimulus GO:0048584 323 0.099
nucleobase containing compound catabolic process GO:0034655 165 0.096
regulation of mrna 3 end processing GO:0031440 7 0.096
cytoplasm organization GO:0007028 64 0.095
cellular response to chemical stimulus GO:0070887 199 0.094
Worm
aromatic compound catabolic process GO:0019439 166 0.094
fertilization GO:0009566 26 0.092
mrna processing GO:0006397 104 0.092
developmental maturation GO:0021700 172 0.090
regulation of protein metabolic process GO:0051246 256 0.088
Mouse
mitotic chromosome condensation GO:0007076 22 0.084
translation GO:0006412 69 0.083
Mouse
epithelial cell differentiation GO:0030855 322 0.083
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.082
germarium derived oocyte differentiation GO:0030706 29 0.081
oocyte dorsal ventral axis specification GO:0007310 34 0.080
maternal determination of anterior posterior axis embryo GO:0008358 74 0.078
dna metabolic process GO:0006259 227 0.078
mrna 3 end processing GO:0031124 28 0.077
pole plasm rna localization GO:0007316 52 0.071
synaptic transmission GO:0007268 288 0.070
dna packaging GO:0006323 91 0.068
spindle organization GO:0007051 253 0.067
macromolecular complex assembly GO:0065003 256 0.065
regulation of catabolic process GO:0009894 170 0.065
catabolic process GO:0009056 409 0.065
regulation of immune response GO:0050776 118 0.064
positive regulation of biosynthetic process GO:0009891 316 0.064
Mouse
regulation of nuclear transcribed mrna poly a tail shortening GO:0060211 4 0.061
single organism cellular localization GO:1902580 180 0.061
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.059
negative regulation of response to stimulus GO:0048585 258 0.058
Zebrafish
regulation of mrna metabolic process GO:1903311 72 0.057
female meiotic division GO:0007143 70 0.057
dorsal ventral pattern formation GO:0009953 133 0.056
oocyte localization involved in germarium derived egg chamber formation GO:0030720 12 0.056
cellular macromolecule catabolic process GO:0044265 136 0.055
macromolecule catabolic process GO:0009057 161 0.055
intracellular signal transduction GO:0035556 300 0.055
regulation of localization GO:0032879 275 0.055
nucleobase containing small molecule metabolic process GO:0055086 174 0.054
protein complex biogenesis GO:0070271 201 0.052
Zebrafish
oxoacid metabolic process GO:0043436 103 0.052
ovarian follicle cell development GO:0030707 248 0.050
blastoderm segmentation GO:0007350 159 0.049
embryonic axis specification GO:0000578 107 0.049
organic cyclic compound catabolic process GO:1901361 168 0.049
small molecule metabolic process GO:0044281 305 0.048
regulation of organelle organization GO:0033043 196 0.048
Mouse
negative regulation of cell development GO:0010721 62 0.048
negative regulation of oskar mrna translation GO:0007319 5 0.046
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.046
regulation of cellular ketone metabolic process GO:0010565 3 0.046
chromosome condensation GO:0030261 41 0.045
mitotic dna integrity checkpoint GO:0044774 75 0.044
mrna polyadenylation GO:0006378 11 0.043
meiosis i GO:0007127 59 0.041
Mouse
cell proliferation GO:0008283 299 0.041
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.041
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.041
regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay GO:1900151 4 0.040
transmembrane transport GO:0055085 139 0.040
polarity specification of anterior posterior axis GO:0009949 5 0.040
cellular macromolecule localization GO:0070727 220 0.040
microtubule organizing center organization GO:0031023 168 0.039
oocyte fate determination GO:0030716 27 0.039
positive regulation of nucleic acid templated transcription GO:1903508 266 0.039
rna polyadenylation GO:0043631 12 0.039
organonitrogen compound metabolic process GO:1901564 318 0.039
purine ribonucleoside metabolic process GO:0046128 127 0.038
heterocycle catabolic process GO:0046700 166 0.038
negative regulation of multicellular organismal process GO:0051241 142 0.037
production of small rna involved in gene silencing by rna GO:0070918 15 0.034
Worm
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.034
positive regulation of cellular protein metabolic process GO:0032270 118 0.034
Mouse
nucleus organization GO:0006997 45 0.033
compound eye morphogenesis GO:0001745 249 0.033
positive regulation of catabolic process GO:0009896 105 0.033
negative regulation of cell communication GO:0010648 223 0.033
Zebrafish
regulation of oskar mrna translation GO:0046011 8 0.033
rna 3 end processing GO:0031123 45 0.033
positive regulation of protein metabolic process GO:0051247 128 0.032
Mouse
lateral inhibition GO:0046331 206 0.031
cellular macromolecular complex assembly GO:0034622 153 0.031
mitotic spindle organization GO:0007052 220 0.031
rna processing GO:0006396 147 0.031
positive regulation of mrna processing GO:0050685 4 0.030
response to biotic stimulus GO:0009607 294 0.030
eye development GO:0001654 323 0.029
dna alkylation GO:0006305 4 0.029
Mouse
fusome organization GO:0045478 13 0.029
localization of cell GO:0051674 257 0.029
production of sirna involved in rna interference GO:0030422 11 0.028
Worm
dsrna fragmentation GO:0031050 15 0.028
Worm
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.028
stem cell maintenance GO:0019827 67 0.028
Zebrafish Mouse Fly
chromosome organization GO:0051276 360 0.028
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.028
Mouse
negative regulation of translation GO:0017148 28 0.027
regulation of anatomical structure morphogenesis GO:0022603 242 0.027
mitotic nuclear division GO:0007067 213 0.027
stem cell differentiation GO:0048863 117 0.027
Zebrafish Mouse Fly
organophosphate metabolic process GO:0019637 195 0.027
photoreceptor cell differentiation GO:0046530 170 0.027
organic acid metabolic process GO:0006082 103 0.027
regulation of cellular amino acid metabolic process GO:0006521 0 0.027
positive regulation of catalytic activity GO:0043085 118 0.027
pole plasm oskar mrna localization GO:0045451 46 0.027
taxis GO:0042330 304 0.026
nucleoside triphosphate catabolic process GO:0009143 108 0.026
purine nucleoside metabolic process GO:0042278 127 0.026
positive regulation of phosphorus metabolic process GO:0010562 139 0.026
protein complex assembly GO:0006461 200 0.026
Zebrafish
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 18 0.026
Zebrafish
anterior posterior axis specification embryo GO:0008595 103 0.025
dna methylation GO:0006306 4 0.025
Mouse
axon development GO:0061564 297 0.025
positive regulation of signal transduction GO:0009967 223 0.025
regulation of protein complex assembly GO:0043254 42 0.024
Zebrafish
positive regulation of defense response GO:0031349 59 0.024
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.024
male meiosis cytokinesis GO:0007112 26 0.024
positive regulation of cellular amine metabolic process GO:0033240 0 0.023
meiotic spindle organization GO:0000212 36 0.023
cytokinesis GO:0000910 90 0.023
ovarian fusome organization GO:0030723 11 0.023
carbohydrate derivative metabolic process GO:1901135 217 0.023
compound eye development GO:0048749 307 0.022
regulation of embryonic pattern specification GO:1902875 27 0.022
axonogenesis GO:0007409 290 0.022
purine nucleotide metabolic process GO:0006163 146 0.022
dna methylation or demethylation GO:0044728 4 0.021
Mouse
organelle assembly GO:0070925 198 0.021
ribonucleoside catabolic process GO:0042454 112 0.021
apoptotic process GO:0006915 159 0.021
positive regulation of transcription dna templated GO:0045893 266 0.021
cellular catabolic process GO:0044248 372 0.021
dorsal ventral axis specification ovarian follicular epithelium GO:0008069 13 0.021
regulation of cellular catabolic process GO:0031329 157 0.021
negative regulation of cell cycle GO:0045786 116 0.020
nuclear migration GO:0007097 20 0.020
chorion containing eggshell pattern formation GO:0030381 11 0.020
positive regulation of signaling GO:0023056 243 0.019
chemotaxis GO:0006935 249 0.019
purine nucleoside catabolic process GO:0006152 112 0.019
mitotic dna damage checkpoint GO:0044773 74 0.019
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.019
regulation of synaptic transmission GO:0050804 69 0.019
compound eye photoreceptor cell differentiation GO:0001751 140 0.019
cell cell signaling involved in cell fate commitment GO:0045168 210 0.019
cellular protein complex assembly GO:0043623 71 0.018
Zebrafish
nucleoside triphosphate metabolic process GO:0009141 120 0.018
tripartite regional subdivision GO:0007351 103 0.018
cell death GO:0008219 279 0.018
positive regulation of hydrolase activity GO:0051345 78 0.017
purine containing compound catabolic process GO:0072523 112 0.017
mitotic cell cycle checkpoint GO:0007093 88 0.017
positive regulation of molecular function GO:0044093 136 0.017
positive regulation of rna biosynthetic process GO:1902680 266 0.017
dorsal ventral axis specification GO:0009950 66 0.017
regulation of cellular amine metabolic process GO:0033238 3 0.017
ribonucleotide metabolic process GO:0009259 145 0.016
germ line stem cell maintenance GO:0030718 50 0.016
Zebrafish Mouse Fly
negative regulation of nervous system development GO:0051961 92 0.016
positive regulation of immune system process GO:0002684 68 0.016
embryo development ending in birth or egg hatching GO:0009792 152 0.016
Worm
regulation of cell cycle process GO:0010564 181 0.016
Mouse
regulation of translation GO:0006417 56 0.016
Mouse
oocyte microtubule cytoskeleton organization GO:0016325 35 0.016
negative regulation of neurogenesis GO:0050768 53 0.016
cellular component assembly involved in morphogenesis GO:0010927 151 0.016
regulation of cellular localization GO:0060341 136 0.016
single organism nuclear import GO:1902593 51 0.016
sex differentiation GO:0007548 81 0.016
positive regulation of cellular component organization GO:0051130 156 0.016
Mouse
nucleoside phosphate catabolic process GO:1901292 110 0.015
response to light stimulus GO:0009416 124 0.015
pole plasm mrna localization GO:0019094 49 0.015
body morphogenesis GO:0010171 2 0.015
peptidyl lysine acetylation GO:0018394 39 0.015
wound healing GO:0042060 75 0.015
spindle assembly involved in meiosis GO:0090306 20 0.015
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.015
Zebrafish
cell fate specification GO:0001708 71 0.015
cellular amino acid metabolic process GO:0006520 61 0.015
regulation of cellular protein metabolic process GO:0032268 243 0.015
Mouse
regulation of gene silencing GO:0060968 63 0.015
purine ribonucleotide metabolic process GO:0009150 145 0.014
ribonucleoside triphosphate metabolic process GO:0009199 119 0.014
nuclear transcribed mrna poly a tail shortening GO:0000289 12 0.014
response to hypoxia GO:0001666 53 0.014
protein ubiquitination GO:0016567 70 0.014
regulation of apoptotic process GO:0042981 130 0.014
positive regulation of phosphate metabolic process GO:0045937 139 0.013
glycosyl compound metabolic process GO:1901657 127 0.013
positive regulation of cellular biosynthetic process GO:0031328 316 0.013
Mouse
regulation of cell proliferation GO:0042127 163 0.013
cellular protein modification process GO:0006464 438 0.013
sensory organ morphogenesis GO:0090596 260 0.013
response to other organism GO:0051707 293 0.013
negative regulation of cellular component organization GO:0051129 108 0.013
Zebrafish
death GO:0016265 284 0.013
regulation of transposition rna mediated GO:0010525 3 0.013
single organism catabolic process GO:0044712 228 0.013
cell motility GO:0048870 251 0.013
regulation of intracellular signal transduction GO:1902531 236 0.012
reproductive structure development GO:0048608 74 0.012
negative regulation of gene expression epigenetic GO:0045814 77 0.012
ribonucleoside triphosphate catabolic process GO:0009203 108 0.012
negative regulation of transcription dna templated GO:0045892 237 0.012
embryonic cleavage GO:0040016 5 0.012
spindle assembly GO:0051225 80 0.012
cellular response to nitrogen compound GO:1901699 51 0.012
Worm
polarity specification of dorsal ventral axis GO:0009951 6 0.012
establishment of localization in cell GO:0051649 402 0.012
olfactory behavior GO:0042048 97 0.012
nucleoside metabolic process GO:0009116 127 0.012
positive regulation of organelle organization GO:0010638 65 0.011
Mouse
defense response to bacterium GO:0042742 178 0.011
organophosphate catabolic process GO:0046434 112 0.011
positive regulation of cellular component biogenesis GO:0044089 80 0.011
defense response to gram negative bacterium GO:0050829 94 0.011
regulation of developmental growth GO:0048638 174 0.011
salivary gland morphogenesis GO:0007435 145 0.011
positive regulation of cell communication GO:0010647 250 0.011
response to dsrna GO:0043331 15 0.011
Worm
regulation of organ growth GO:0046620 42 0.011
carboxylic acid metabolic process GO:0019752 92 0.011
neuron projection guidance GO:0097485 241 0.011
mesenchymal cell development GO:0014031 1 0.011
regulation of response to external stimulus GO:0032101 115 0.011
establishment of nucleus localization GO:0040023 26 0.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.011
Zebrafish
regulation of mrna catabolic process GO:0061013 5 0.011
meiotic chromosome segregation GO:0045132 59 0.010
nucleotide catabolic process GO:0009166 109 0.010
response to oxygen containing compound GO:1901700 200 0.010
purine ribonucleoside catabolic process GO:0046130 112 0.010
secretion by cell GO:0032940 101 0.010
pronuclear fusion GO:0007344 4 0.010
ribonucleoside monophosphate metabolic process GO:0009161 51 0.010
immune response GO:0006955 246 0.010

aub disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.024
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
organ system cancer DOID:0050686 0 0.011