Drosophila melanogaster

113 known processes

wls (Dmel_CG6210)

wntless

(Aliases: Evi,Dmel\CG6210,srt,evi,Wls/Evi,Wls,Evi/Wls,Srt,wls/evi,CG6210)

wls biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regionalization GO:0003002 416 0.984
establishment of localization in cell GO:0051649 402 0.933
regulation of multicellular organismal development GO:2000026 414 0.930
positive regulation of wnt signaling pathway GO:0030177 25 0.872
positive regulation of signaling GO:0023056 243 0.840
positive regulation of macromolecule metabolic process GO:0010604 405 0.838
segmentation GO:0035282 207 0.818
secretion GO:0046903 109 0.817
signal release GO:0023061 49 0.805
axonogenesis GO:0007409 290 0.791
regulation of localization GO:0032879 275 0.773
tissue morphogenesis GO:0048729 297 0.764
Mouse
dorsal ventral pattern formation GO:0009953 133 0.699
chemotaxis GO:0006935 249 0.679
intracellular transport GO:0046907 228 0.675
enzyme linked receptor protein signaling pathway GO:0007167 179 0.641
positive regulation of transport GO:0051050 92 0.623
eye morphogenesis GO:0048592 260 0.611
protein modification process GO:0036211 438 0.561
anterior posterior pattern specification GO:0009952 136 0.500
Zebrafish Mouse
tube development GO:0035295 244 0.498
Zebrafish Mouse Worm
single organism intracellular transport GO:1902582 207 0.492
establishment of protein localization GO:0045184 163 0.492
negative regulation of gene expression GO:0010629 387 0.485
positive regulation of biosynthetic process GO:0009891 316 0.478
digestive tract development GO:0048565 149 0.465
Mouse Worm
spindle organization GO:0007051 253 0.460
protein localization GO:0008104 284 0.438
developmental growth GO:0048589 280 0.403
posttranscriptional regulation of gene expression GO:0010608 145 0.400
appendage development GO:0048736 401 0.398
tube morphogenesis GO:0035239 191 0.397
Mouse Worm
regulation of transport GO:0051049 181 0.395
neuron projection guidance GO:0097485 241 0.390
embryonic morphogenesis GO:0048598 206 0.388
Mouse Worm
regulation of nervous system development GO:0051960 248 0.384
carbohydrate derivative biosynthetic process GO:1901137 85 0.377
regulation of neurogenesis GO:0050767 158 0.352
transmembrane transport GO:0055085 139 0.350
positive regulation of cell communication GO:0010647 250 0.340
positive regulation of secretion GO:0051047 22 0.339
positive regulation of rna biosynthetic process GO:1902680 266 0.328
transcription from rna polymerase ii promoter GO:0006366 368 0.312
secretion by cell GO:0032940 101 0.309
organic substance transport GO:0071702 257 0.309
regulation of neuron differentiation GO:0045664 103 0.296
non canonical wnt signaling pathway GO:0035567 8 0.296
Worm
digestive tract morphogenesis GO:0048546 127 0.291
Mouse Worm
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.285
regulation of notch signaling pathway GO:0008593 100 0.281
axon guidance GO:0007411 233 0.273
response to oxygen containing compound GO:1901700 200 0.263
positive regulation of transcription dna templated GO:0045893 266 0.261
appendage morphogenesis GO:0035107 397 0.249
cellular protein modification process GO:0006464 438 0.244
imaginal disc growth GO:0007446 37 0.231
endocytosis GO:0006897 310 0.231
regulation of wnt signaling pathway GO:0030111 68 0.223
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.221
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.219
synapse organization GO:0050808 196 0.214
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.214
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.213
eye development GO:0001654 323 0.212
epithelial cell differentiation GO:0030855 322 0.211
male gamete generation GO:0048232 201 0.210
positive regulation of gene expression GO:0010628 290 0.209
imaginal disc derived wing morphogenesis GO:0007476 337 0.206
regulation of gene expression epigenetic GO:0040029 128 0.204
mitochondrion organization GO:0007005 65 0.203
notch signaling pathway GO:0007219 120 0.199
regulation of cellular protein metabolic process GO:0032268 243 0.193
organelle localization GO:0051640 148 0.191
Worm
glycoprotein biosynthetic process GO:0009101 41 0.191
imaginal disc derived appendage morphogenesis GO:0035114 395 0.187
cytoplasmic transport GO:0016482 130 0.186
regulation of cellular localization GO:0060341 136 0.185
single organism cellular localization GO:1902580 180 0.181
Worm
cellular macromolecule localization GO:0070727 220 0.180
axon development GO:0061564 297 0.179
neurological system process GO:0050877 358 0.178
regulation of epithelial cell proliferation GO:0050678 4 0.173
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.162
cell migration GO:0016477 238 0.157
Worm
mitotic spindle organization GO:0007052 220 0.157
eye antennal disc morphogenesis GO:0007455 34 0.156
ovarian follicle cell development GO:0030707 248 0.154
catabolic process GO:0009056 409 0.154
positive regulation of developmental process GO:0051094 143 0.153
oxoacid metabolic process GO:0043436 103 0.150
positive regulation of cell development GO:0010720 61 0.150
organic acid metabolic process GO:0006082 103 0.150
glycoprotein metabolic process GO:0009100 41 0.146
retinal ganglion cell axon guidance GO:0031290 12 0.145
segment polarity determination GO:0007367 25 0.143
regulation of developmental growth GO:0048638 174 0.142
regulation of protein metabolic process GO:0051246 256 0.142
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.140
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.138
spermatogenesis GO:0007283 200 0.138
regulation of cellular component biogenesis GO:0044087 201 0.135
positive regulation of rna metabolic process GO:0051254 271 0.134
negative regulation of cell communication GO:0010648 223 0.134
negative regulation of rna metabolic process GO:0051253 251 0.134
post embryonic appendage morphogenesis GO:0035120 385 0.132
imaginal disc derived appendage development GO:0048737 399 0.132
compound eye development GO:0048749 307 0.131
compound eye morphogenesis GO:0001745 249 0.131
macromolecular complex assembly GO:0065003 256 0.123
periodic partitioning GO:0007365 29 0.121
central nervous system development GO:0007417 201 0.117
Zebrafish
response to endogenous stimulus GO:0009719 119 0.117
positive regulation of nucleic acid templated transcription GO:1903508 266 0.115
forebrain development GO:0030900 2 0.110
positive regulation of multicellular organismal process GO:0051240 143 0.110
intracellular protein transport GO:0006886 104 0.109
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.109
wing disc morphogenesis GO:0007472 344 0.106
brain development GO:0007420 120 0.103
Zebrafish
signal transduction by phosphorylation GO:0023014 107 0.103
cell cell signaling involved in cell fate commitment GO:0045168 210 0.102
stem cell development GO:0048864 79 0.101
establishment of organelle localization GO:0051656 122 0.099
Worm
regulation of cell development GO:0060284 215 0.099
head development GO:0060322 135 0.098
Zebrafish
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 19 0.098
taxis GO:0042330 304 0.098
embryonic axis specification GO:0000578 107 0.096
anterior posterior axis specification GO:0009948 109 0.096
Mouse
eye antennal disc development GO:0035214 60 0.092
sensory organ morphogenesis GO:0090596 260 0.092
negative regulation of heart induction GO:1901320 3 0.092
cellular response to organic substance GO:0071310 132 0.091
positive regulation of nervous system development GO:0051962 69 0.088
positive regulation of protein metabolic process GO:0051247 128 0.087
growth GO:0040007 359 0.086
germarium derived egg chamber formation GO:0007293 101 0.085
imaginal disc derived wing margin morphogenesis GO:0008587 41 0.085
imaginal disc pattern formation GO:0007447 91 0.085
gastrulation GO:0007369 70 0.083
Mouse Worm
vesicle mediated transport GO:0016192 381 0.083
protein transport GO:0015031 155 0.082
nucleocytoplasmic transport GO:0006913 72 0.081
negative regulation of signal transduction GO:0009968 206 0.079
cellular protein localization GO:0034613 160 0.079
mitochondrion distribution GO:0048311 10 0.078
negative regulation of signaling GO:0023057 219 0.075
morphogenesis of an epithelium GO:0002009 276 0.075
cellular amine metabolic process GO:0044106 12 0.075
stem cell maintenance GO:0019827 67 0.074
germ cell migration GO:0008354 43 0.074
lipid metabolic process GO:0006629 121 0.074
endodermal cell fate commitment GO:0001711 3 0.073
Worm
biological adhesion GO:0022610 138 0.073
spermatid differentiation GO:0048515 114 0.073
learning or memory GO:0007611 141 0.071
positive regulation of cellular biosynthetic process GO:0031328 316 0.071
single organism cell adhesion GO:0098602 47 0.070
skin development GO:0043588 65 0.070
regulation of protein transport GO:0051223 57 0.070
regulation of endocytosis GO:0030100 37 0.070
regulation of anatomical structure morphogenesis GO:0022603 242 0.070
camera type eye development GO:0043010 4 0.069
phagocytosis GO:0006909 215 0.068
regulation of protein phosphorylation GO:0001932 64 0.067
notch receptor processing GO:0007220 13 0.066
cellular carbohydrate metabolic process GO:0044262 22 0.066
cellular macromolecule catabolic process GO:0044265 136 0.066
regulation of imaginal disc growth GO:0045570 26 0.065
cytoskeleton dependent cytokinesis GO:0061640 81 0.065
negative regulation of nucleic acid templated transcription GO:1903507 240 0.065
sensory perception GO:0007600 196 0.065
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.064
macromolecule catabolic process GO:0009057 161 0.064
regulation of vesicle mediated transport GO:0060627 59 0.063
retina morphogenesis in camera type eye GO:0060042 2 0.062
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.061
positive regulation of cell differentiation GO:0045597 64 0.061
imaginal disc derived wing vein specification GO:0007474 48 0.060
cytokinesis GO:0000910 90 0.060
peptidyl threonine phosphorylation GO:0018107 2 0.058
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.058
cell surface receptor signaling pathway involved in heart development GO:0061311 3 0.058
positive regulation of response to stimulus GO:0048584 323 0.057
proteolysis GO:0006508 192 0.057
response to organic substance GO:0010033 284 0.057
regulation of secretion by cell GO:1903530 39 0.056
endomembrane system organization GO:0010256 119 0.056
negative regulation of cellular protein metabolic process GO:0032269 85 0.056
dna templated transcription elongation GO:0006354 18 0.055
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.054
single organism carbohydrate metabolic process GO:0044723 72 0.054
chaeta development GO:0022416 97 0.054
axis specification GO:0009798 167 0.053
Mouse
protein complex assembly GO:0006461 200 0.052
organonitrogen compound metabolic process GO:1901564 318 0.052
mitotic nuclear division GO:0007067 213 0.051
cellular homeostasis GO:0019725 80 0.049
protein glycosylation GO:0006486 32 0.049
regulation of cellular amine metabolic process GO:0033238 3 0.049
ubiquitin dependent protein catabolic process GO:0006511 78 0.049
protein phosphorylation GO:0006468 169 0.048
multicellular organism growth GO:0035264 46 0.048
cellular lipid metabolic process GO:0044255 83 0.047
negative regulation of heart induction by canonical wnt signaling pathway GO:0003136 3 0.047
cellular ketone metabolic process GO:0042180 24 0.046
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.046
nuclear transport GO:0051169 72 0.046
regulation of smoothened signaling pathway GO:0008589 28 0.046
regulation of protein localization GO:0032880 76 0.046
leg disc morphogenesis GO:0007478 80 0.045
single organism biosynthetic process GO:0044711 206 0.045
positive regulation of cellular component organization GO:0051130 156 0.045
vesicle organization GO:0016050 44 0.045
carbohydrate derivative metabolic process GO:1901135 217 0.045
synapse assembly GO:0007416 143 0.044
negative regulation of cellular biosynthetic process GO:0031327 277 0.044
digestive system development GO:0055123 149 0.044
Mouse Worm
regulation of organ growth GO:0046620 42 0.042
nuclear export GO:0051168 24 0.041
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.041
heart field specification GO:0003128 0 0.040
embryonic pattern specification GO:0009880 174 0.040
anterograde axon cargo transport GO:0008089 6 0.040
carbohydrate biosynthetic process GO:0016051 17 0.040
proteasomal protein catabolic process GO:0010498 59 0.039
mesenchyme development GO:0060485 9 0.039
cellular amino acid metabolic process GO:0006520 61 0.039
cellular response to endogenous stimulus GO:0071495 80 0.039
cardiovascular system development GO:0072358 82 0.039
actin cytoskeleton organization GO:0030036 206 0.038
positive regulation of neurogenesis GO:0050769 41 0.038
negative regulation of phosphorus metabolic process GO:0010563 45 0.038
pigmentation GO:0043473 75 0.038
negative regulation of notch signaling pathway GO:0045746 41 0.038
regulation of cell differentiation GO:0045595 302 0.038
meiotic g2 mi transition GO:0008315 3 0.038
female sex differentiation GO:0046660 20 0.037
camera type eye morphogenesis GO:0048593 2 0.037
regulation of stem cell proliferation GO:0072091 40 0.036
regulation of metal ion transport GO:0010959 15 0.036
dorsal ventral pattern formation imaginal disc GO:0007450 51 0.036
positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743 5 0.036
intracellular signal transduction GO:0035556 300 0.034
body morphogenesis GO:0010171 2 0.034
transition metal ion transport GO:0000041 16 0.034
mitotic cytokinesis GO:0000281 50 0.034
histone modification GO:0016570 106 0.034
positive regulation of receptor mediated endocytosis GO:0048260 7 0.033
dorsal appendage formation GO:0046843 47 0.033
sleep GO:0030431 49 0.032
programmed cell death GO:0012501 257 0.032
response to alcohol GO:0097305 95 0.032
negative regulation of programmed cell death GO:0043069 72 0.032
regulation of synapse assembly GO:0051963 94 0.032
protein complex biogenesis GO:0070271 201 0.032
organelle assembly GO:0070925 198 0.031
aggressive behavior GO:0002118 63 0.031
regulation of nucleocytoplasmic transport GO:0046822 35 0.031
wing disc pattern formation GO:0035222 66 0.031
regulation of system process GO:0044057 36 0.030
protein modification by small protein conjugation or removal GO:0070647 106 0.030
chaeta morphogenesis GO:0008407 42 0.030
amine metabolic process GO:0009308 12 0.030
centrosome organization GO:0051297 163 0.030
establishment of protein localization to organelle GO:0072594 62 0.030
cellular response to oxygen containing compound GO:1901701 79 0.029
regulation of protein serine threonine kinase activity GO:0071900 25 0.029
histone methylation GO:0016571 40 0.029
negative regulation of protein phosphorylation GO:0001933 17 0.029
cellular response to chemical stimulus GO:0070887 199 0.029
segment specification GO:0007379 33 0.028
organic substance catabolic process GO:1901575 308 0.028
peptidyl amino acid modification GO:0018193 105 0.028
mesenchymal cell differentiation GO:0048762 1 0.028
actin filament based process GO:0030029 220 0.027
circulatory system development GO:0072359 82 0.027
retina development in camera type eye GO:0060041 4 0.027
protein modification by small protein conjugation GO:0032446 79 0.027
regulation of endopeptidase activity GO:0052548 36 0.027
regulation of protein modification process GO:0031399 112 0.027
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.027
single organism behavior GO:0044708 391 0.027
columnar cuboidal epithelial cell development GO:0002066 249 0.027
cognition GO:0050890 141 0.027
canonical wnt signaling pathway involved in heart development GO:0061316 3 0.027
smoothened signaling pathway GO:0007224 49 0.026
regulation of intracellular transport GO:0032386 64 0.026
imaginal disc derived leg morphogenesis GO:0007480 80 0.026
mesoderm development GO:0007498 78 0.026
Mouse
single organismal cell cell adhesion GO:0016337 45 0.026
meiotic cell cycle phase transition GO:0044771 4 0.025
regulation of cellular ketone metabolic process GO:0010565 3 0.025
asymmetric cell division GO:0008356 37 0.025
regulation of cell cycle GO:0051726 291 0.025
Worm
leg disc development GO:0035218 92 0.025
carbohydrate metabolic process GO:0005975 82 0.025
response to hexose GO:0009746 3 0.025
blastoderm segmentation GO:0007350 159 0.025
regulation of locomotion GO:0040012 42 0.025
Worm
gene silencing GO:0016458 138 0.025
interspecies interaction between organisms GO:0044419 16 0.025
learning GO:0007612 75 0.025
cell adhesion GO:0007155 136 0.025
regulation of proteasomal protein catabolic process GO:0061136 39 0.025
response to hormone GO:0009725 45 0.025
regulation of phosphorus metabolic process GO:0051174 210 0.024
apical junction assembly GO:0043297 32 0.024
regulation of microtubule based process GO:0032886 49 0.024
Worm
wnt signaling pathway GO:0016055 98 0.024
cellular nitrogen compound catabolic process GO:0044270 165 0.024
transcription elongation from rna polymerase ii promoter GO:0006368 18 0.024
methylation GO:0032259 47 0.023
regulation of molecular function GO:0065009 217 0.023
modification dependent protein catabolic process GO:0019941 78 0.023
embryonic organ development GO:0048568 50 0.023
ameboidal type cell migration GO:0001667 151 0.023
small molecule metabolic process GO:0044281 305 0.023
sex differentiation GO:0007548 81 0.023
positive regulation of signal transduction GO:0009967 223 0.023
negative regulation of developmental process GO:0051093 201 0.023
protein import GO:0017038 55 0.023
lateral inhibition GO:0046331 206 0.023
negative regulation of cardioblast differentiation GO:0051892 7 0.022
connective tissue development GO:0061448 3 0.022
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.022
chemosensory behavior GO:0007635 106 0.022
spermatid development GO:0007286 98 0.022
oocyte development GO:0048599 124 0.022
gene silencing by rna GO:0031047 57 0.022
organ formation GO:0048645 39 0.022
protein modification by small protein removal GO:0070646 28 0.022
negative regulation of protein modification process GO:0031400 29 0.022
cell death GO:0008219 279 0.021
autophagy GO:0006914 108 0.021
protein ubiquitination GO:0016567 70 0.021
stem cell differentiation GO:0048863 117 0.021
regulation of epithelial cell differentiation GO:0030856 4 0.021
extracellular structure organization GO:0043062 46 0.021
regulation of intracellular protein transport GO:0033157 46 0.021
cuticle development GO:0042335 86 0.021
sperm individualization GO:0007291 48 0.021
regulation of secretion GO:0051046 44 0.021
regulation of cellular protein catabolic process GO:1903362 44 0.020
cellular macromolecular complex assembly GO:0034622 153 0.020
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 15 0.020
positive regulation of hh target transcription factor activity GO:0007228 5 0.020
cuticle pattern formation GO:0035017 27 0.020
negative regulation of rna biosynthetic process GO:1902679 240 0.019
neuromuscular junction development GO:0007528 149 0.019
modification dependent macromolecule catabolic process GO:0043632 79 0.019
regulation of cell death GO:0010941 173 0.019
negative regulation of cell death GO:0060548 81 0.019
heparan sulfate proteoglycan biosynthetic process polysaccharide chain biosynthetic process GO:0015014 5 0.019
actomyosin structure organization GO:0031032 56 0.019
negative regulation of microtubule polymerization or depolymerization GO:0031111 21 0.019
response to external biotic stimulus GO:0043207 293 0.018
aromatic compound catabolic process GO:0019439 166 0.018
regulation of multicellular organism growth GO:0040014 40 0.018
negative regulation of cellular metabolic process GO:0031324 382 0.018
oocyte microtubule cytoskeleton organization GO:0016325 35 0.018
cation transport GO:0006812 110 0.018
synaptic vesicle recycling GO:0036465 28 0.018
locomotory behavior GO:0007626 176 0.018
negative regulation of protein metabolic process GO:0051248 85 0.018
regulation of cell shape GO:0008360 113 0.018
protein targeting GO:0006605 64 0.018
cellular response to peptide GO:1901653 28 0.018
protein export from nucleus GO:0006611 10 0.018
regulation of growth GO:0040008 233 0.018
cellular response to hexose stimulus GO:0071331 1 0.017
regulation of cellular component movement GO:0051270 42 0.017
Worm
apoptotic process GO:0006915 159 0.017
cellular response to insulin stimulus GO:0032869 28 0.017
positive regulation of jun kinase activity GO:0043507 4 0.017
positive regulation of neuron differentiation GO:0045666 26 0.017
response to extracellular stimulus GO:0009991 116 0.017
developmental programmed cell death GO:0010623 138 0.017
positive regulation of cellular protein metabolic process GO:0032270 118 0.017
eye pigmentation GO:0048069 43 0.017
synaptic vesicle transport GO:0048489 50 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.017
regulation of mrna processing GO:0050684 71 0.016
positive regulation of intracellular signal transduction GO:1902533 116 0.016
negative regulation of transferase activity GO:0051348 18 0.016
regulation of synapse structure and activity GO:0050803 128 0.016
actin filament bundle assembly GO:0051017 26 0.016
embryonic development via the syncytial blastoderm GO:0001700 148 0.016
regulation of cellular catabolic process GO:0031329 157 0.016
proteoglycan metabolic process GO:0006029 10 0.016
wing disc dorsal ventral pattern formation GO:0048190 47 0.016
negative regulation of molecular function GO:0044092 51 0.016
oocyte axis specification GO:0007309 108 0.016
multi organism behavior GO:0051705 175 0.016
cellular protein catabolic process GO:0044257 83 0.015
regulation of actin cytoskeleton organization GO:0032956 42 0.015
synaptic transmission GO:0007268 288 0.015
epithelial cell development GO:0002064 274 0.015
nucleus localization GO:0051647 34 0.015
regulation of establishment of protein localization GO:0070201 61 0.015
canonical wnt signaling pathway GO:0060070 21 0.015
regulation of synapse organization GO:0050807 110 0.015
gene silencing by mirna GO:0035195 22 0.015
multi multicellular organism process GO:0044706 123 0.015
positive regulation of cellular protein catabolic process GO:1903364 24 0.015
response to lipid GO:0033993 38 0.015
cellular component assembly involved in morphogenesis GO:0010927 151 0.015
oocyte construction GO:0007308 112 0.015
positive regulation of notch signaling pathway GO:0045747 34 0.014
glycosylation GO:0070085 36 0.014
chondroitin sulfate metabolic process GO:0030204 2 0.014
endoderm formation GO:0001706 3 0.014
Worm
positive regulation of proteasomal protein catabolic process GO:1901800 20 0.014
positive regulation of organelle organization GO:0010638 65 0.014
convergent extension GO:0060026 2 0.014
cell aging GO:0007569 2 0.014
protein catabolic process GO:0030163 101 0.014
negative regulation of apoptotic process GO:0043066 63 0.014
regulation of actin filament based process GO:0032970 42 0.014
positive regulation of phosphorylation GO:0042327 87 0.014
regulation of protein complex assembly GO:0043254 42 0.014
positive regulation of cellular amine metabolic process GO:0033240 0 0.014
microtubule depolymerization GO:0007019 25 0.014
mesoderm formation GO:0001707 21 0.014
Mouse
aging GO:0007568 143 0.013
positive regulation of molecular function GO:0044093 136 0.013
negative regulation of kinase activity GO:0033673 16 0.013
regulation of organ morphogenesis GO:2000027 78 0.013
ion transmembrane transport GO:0034220 122 0.013
regulation of canonical wnt signaling pathway GO:0060828 15 0.013
positive regulation of catalytic activity GO:0043085 118 0.013
cell division GO:0051301 248 0.013
chromosome organization GO:0051276 360 0.013
regulation of protein complex disassembly GO:0043244 29 0.013
response to glucose GO:0009749 2 0.013
regulation of mitotic cell cycle GO:0007346 190 0.013
Worm
limb morphogenesis GO:0035108 1 0.013
cellular polysaccharide metabolic process GO:0044264 11 0.013
dendrite development GO:0016358 204 0.013
positive regulation of canonical wnt signaling pathway GO:0090263 7 0.012
positive regulation of cellular component biogenesis GO:0044089 80 0.012
carboxylic acid metabolic process GO:0019752 92 0.012
larval lymph gland hemocyte differentiation GO:0035168 11 0.012
mitochondrion localization GO:0051646 17 0.012
tissue migration GO:0090130 155 0.012
photoreceptor cell differentiation GO:0046530 170 0.012
peptidyl threonine modification GO:0018210 3 0.012
sulfur compound metabolic process GO:0006790 59 0.012
negative regulation of multicellular organismal process GO:0051241 142 0.012
mitotic cell cycle embryonic GO:0045448 38 0.012
membrane lipid metabolic process GO:0006643 22 0.012
positive regulation of lipid biosynthetic process GO:0046889 3 0.012
tripartite regional subdivision GO:0007351 103 0.012
regulation of compound eye pigmentation GO:0048076 7 0.012
aminoglycan metabolic process GO:0006022 18 0.012
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.012
intracellular distribution of mitochondria GO:0048312 5 0.012
establishment of tissue polarity GO:0007164 87 0.012
substrate dependent cell migration GO:0006929 3 0.012
regulation of mrna metabolic process GO:1903311 72 0.012
histone h3 k4 methylation GO:0051568 16 0.011
protein methylation GO:0006479 43 0.011
regulation of proteolysis GO:0030162 87 0.011
morphogenesis of embryonic epithelium GO:0016331 94 0.011
histone ubiquitination GO:0016574 4 0.011
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 3 0.011
regulation of cysteine type endopeptidase activity GO:2000116 27 0.011
regulation of catabolic process GO:0009894 170 0.011
production of small rna involved in gene silencing by rna GO:0070918 15 0.011
respiratory system development GO:0060541 213 0.011
rna processing GO:0006396 147 0.011
mapk cascade GO:0000165 107 0.011
cell growth GO:0016049 108 0.011
reproductive system development GO:0061458 74 0.011
positive regulation of intracellular protein transport GO:0090316 30 0.011
positive regulation of protein catabolic process GO:0045732 34 0.010
cellular response to peptide hormone stimulus GO:0071375 28 0.010
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.010
regulation of cytoplasmic transport GO:1903649 47 0.010
wnt signaling pathway involved in heart development GO:0003306 3 0.010
negative regulation of biosynthetic process GO:0009890 277 0.010
positive regulation of protein phosphorylation GO:0001934 34 0.010
negative regulation of response to stimulus GO:0048585 258 0.010
symbiosis encompassing mutualism through parasitism GO:0044403 16 0.010
imaginal disc derived leg segmentation GO:0036011 26 0.010

wls disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.060
organ system cancer DOID:0050686 0 0.024
cancer DOID:162 0 0.024
disease of cellular proliferation DOID:14566 0 0.024
nervous system disease DOID:863 0 0.018
large intestine cancer DOID:5672 0 0.013
colorectal cancer DOID:9256 0 0.013
gastrointestinal system cancer DOID:3119 0 0.013
intestinal cancer DOID:10155 0 0.013