Drosophila melanogaster

41 known processes

DNApol-alpha180 (Dmel_CG6349)

DNA polymerase alpha 180kD

(Aliases: DNA Pol-alpha180,CG6349,DNA polalpha,DNApol-alpha,POLA,E(mus304),pol alpha,DNApola,DNA-Polalpha,183 kDa pol alpha,DmPolalpha,Polalpha,AAB24152,DNApolalpha180,polalpha,DNApolalpha,Dmpol alpha,polalphap180,Dmel\CG6349,Pol,Pol alpha,DNApol)

DNApol-alpha180 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mitotic spindle organization GO:0007052 220 0.347
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.306
cellular macromolecule catabolic process GO:0044265 136 0.304
chromosome separation GO:0051304 42 0.281
cell cycle phase transition GO:0044770 140 0.245
chromosome segregation GO:0007059 157 0.237
mitotic cell cycle phase transition GO:0044772 138 0.233
negative regulation of cell cycle phase transition GO:1901988 103 0.224
chromosome organization GO:0051276 360 0.216
catabolic process GO:0009056 409 0.194
negative regulation of mitotic cell cycle GO:0045930 109 0.169
meiotic nuclear division GO:0007126 151 0.148
mitotic dna damage checkpoint GO:0044773 74 0.144
cellular response to dna damage stimulus GO:0006974 223 0.138
male gamete generation GO:0048232 201 0.136
g2 dna damage checkpoint GO:0031572 69 0.135
sister chromatid segregation GO:0000819 92 0.131
protein modification process GO:0036211 438 0.130
regulation of mitotic cell cycle phase transition GO:1901990 130 0.125
mitotic cell cycle checkpoint GO:0007093 88 0.124
regulation of cell cycle phase transition GO:1901987 130 0.116
mitotic g2 m transition checkpoint GO:0044818 70 0.114
mitotic sister chromatid separation GO:0051306 30 0.103
organic substance catabolic process GO:1901575 308 0.100
ubiquitin dependent protein catabolic process GO:0006511 78 0.099
dna integrity checkpoint GO:0031570 81 0.098
mitotic dna integrity checkpoint GO:0044774 75 0.097
mitotic sister chromatid segregation GO:0000070 87 0.094
protein dna complex subunit organization GO:0071824 86 0.093
negative regulation of cell cycle process GO:0010948 109 0.091
macromolecule catabolic process GO:0009057 161 0.091
regulation of mitotic sister chromatid segregation GO:0033047 28 0.088
cell cycle checkpoint GO:0000075 95 0.085
protein dna complex assembly GO:0065004 63 0.084
spermatogenesis GO:0007283 200 0.083
proteolysis GO:0006508 192 0.083
neuron recognition GO:0008038 101 0.083
dendrite development GO:0016358 204 0.082
regulation of intracellular signal transduction GO:1902531 236 0.079
cellular protein modification process GO:0006464 438 0.076
organelle fission GO:0048285 340 0.075
growth GO:0040007 359 0.074
intracellular signal transduction GO:0035556 300 0.073
heterocycle catabolic process GO:0046700 166 0.072
modification dependent macromolecule catabolic process GO:0043632 79 0.071
axon development GO:0061564 297 0.069
nucleoside catabolic process GO:0009164 112 0.067
cellular protein catabolic process GO:0044257 83 0.065
regulation of protein metabolic process GO:0051246 256 0.059
regulation of cellular protein metabolic process GO:0032268 243 0.057
meiotic cell cycle GO:0051321 171 0.057
nucleobase containing compound catabolic process GO:0034655 165 0.057
cellular catabolic process GO:0044248 372 0.056
regulation of mitotic cell cycle GO:0007346 190 0.056
regulation of neuron differentiation GO:0045664 103 0.056
spindle organization GO:0007051 253 0.056
regulation of chromosome organization GO:0033044 64 0.055
protein catabolic process GO:0030163 101 0.054
modification dependent protein catabolic process GO:0019941 78 0.053
regulation of molecular function GO:0065009 217 0.051
regionalization GO:0003002 416 0.051
centrosome organization GO:0051297 163 0.049
single organism catabolic process GO:0044712 228 0.044
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.044
dna damage checkpoint GO:0000077 78 0.044
ras protein signal transduction GO:0007265 88 0.043
atp metabolic process GO:0046034 49 0.042
organic cyclic compound catabolic process GO:1901361 168 0.042
purine nucleoside metabolic process GO:0042278 127 0.041
regulation of anatomical structure morphogenesis GO:0022603 242 0.041
nucleotide catabolic process GO:0009166 109 0.041
sensory organ morphogenesis GO:0090596 260 0.041
regulation of neuron projection development GO:0010975 69 0.040
regulation of cell cycle process GO:0010564 181 0.040
small gtpase mediated signal transduction GO:0007264 88 0.040
aromatic compound catabolic process GO:0019439 166 0.040
regulation of developmental growth GO:0048638 174 0.039
regulation of mitotic sister chromatid separation GO:0010965 28 0.039
cellular nitrogen compound catabolic process GO:0044270 165 0.039
female meiotic division GO:0007143 70 0.039
imaginal disc derived appendage development GO:0048737 399 0.039
purine containing compound metabolic process GO:0072521 155 0.038
regulation of cell cycle GO:0051726 291 0.038
body morphogenesis GO:0010171 2 0.038
positive regulation of macromolecule metabolic process GO:0010604 405 0.038
regulation of phosphorylation GO:0042325 147 0.038
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.038
nucleoside phosphate metabolic process GO:0006753 162 0.037
regulation of phosphate metabolic process GO:0019220 210 0.037
organophosphate metabolic process GO:0019637 195 0.036
ribonucleotide metabolic process GO:0009259 145 0.034
mitotic g2 dna damage checkpoint GO:0007095 69 0.034
snrna processing GO:0016180 14 0.034
meiotic cell cycle process GO:1903046 132 0.034
dendrite morphogenesis GO:0048813 199 0.033
axonogenesis GO:0007409 290 0.032
purine nucleotide metabolic process GO:0006163 146 0.032
dna replication GO:0006260 48 0.032
dna conformation change GO:0071103 105 0.032
organelle assembly GO:0070925 198 0.031
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.031
negative regulation of chromosome segregation GO:0051985 14 0.030
mitotic spindle elongation GO:0000022 81 0.030
negative regulation of cell cycle GO:0045786 116 0.030
metaphase anaphase transition of cell cycle GO:0044784 28 0.030
chromatin organization GO:0006325 207 0.030
ribose phosphate metabolic process GO:0019693 145 0.029
ribonucleoside triphosphate catabolic process GO:0009203 108 0.029
organophosphate catabolic process GO:0046434 112 0.029
wing disc morphogenesis GO:0007472 344 0.029
regulation of phosphorus metabolic process GO:0051174 210 0.029
eye photoreceptor cell differentiation GO:0001754 145 0.028
metaphase anaphase transition of mitotic cell cycle GO:0007091 28 0.028
dna packaging GO:0006323 91 0.028
photoreceptor cell differentiation GO:0046530 170 0.028
carbohydrate derivative metabolic process GO:1901135 217 0.028
microtubule based transport GO:0010970 42 0.027
regulation of small gtpase mediated signal transduction GO:0051056 93 0.027
imaginal disc derived appendage morphogenesis GO:0035114 395 0.027
centrosome duplication GO:0051298 121 0.027
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.027
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.027
organonitrogen compound metabolic process GO:1901564 318 0.027
axon guidance GO:0007411 233 0.026
histone mrna 3 end processing GO:0006398 8 0.026
nucleotide metabolic process GO:0009117 161 0.026
regulation of proteasomal protein catabolic process GO:0061136 39 0.026
developmental growth GO:0048589 280 0.026
positive regulation of response to stimulus GO:0048584 323 0.025
purine containing compound catabolic process GO:0072523 112 0.025
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.025
dna repair GO:0006281 54 0.025
cytoskeleton dependent intracellular transport GO:0030705 44 0.024
endocytosis GO:0006897 310 0.024
negative regulation of cellular component organization GO:0051129 108 0.024
phosphorylation GO:0016310 294 0.024
nucleobase containing small molecule metabolic process GO:0055086 174 0.024
ribonucleoside triphosphate metabolic process GO:0009199 119 0.024
proteasomal protein catabolic process GO:0010498 59 0.023
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 30 0.023
cellular macromolecular complex assembly GO:0034622 153 0.023
regulation of catabolic process GO:0009894 170 0.023
compound eye development GO:0048749 307 0.023
cell adhesion GO:0007155 136 0.022
centrosome cycle GO:0007098 137 0.022
reproductive system development GO:0061458 74 0.022
imaginal disc derived wing morphogenesis GO:0007476 337 0.022
regulation of protein catabolic process GO:0042176 55 0.022
germ line cyst formation GO:0048134 44 0.022
nucleoside triphosphate catabolic process GO:0009143 108 0.022
glycosyl compound catabolic process GO:1901658 112 0.021
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.021
dna metabolic process GO:0006259 227 0.021
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.020
programmed cell death GO:0012501 257 0.020
regulation of neurogenesis GO:0050767 158 0.020
negative regulation of neuroblast proliferation GO:0007406 27 0.020
phagocytosis GO:0006909 215 0.020
cell proliferation GO:0008283 299 0.020
compound eye morphogenesis GO:0001745 249 0.020
non sensory hair organization GO:0035316 47 0.020
photoreceptor cell development GO:0042461 96 0.020
embryo development ending in birth or egg hatching GO:0009792 152 0.020
positive regulation of phosphate metabolic process GO:0045937 139 0.020
negative regulation of organelle organization GO:0010639 56 0.020
purine ribonucleotide metabolic process GO:0009150 145 0.020
mitotic nuclear division GO:0007067 213 0.019
eye photoreceptor cell development GO:0042462 81 0.019
muscle structure development GO:0061061 224 0.019
purine nucleotide catabolic process GO:0006195 109 0.019
ribonucleotide catabolic process GO:0009261 109 0.019
imaginal disc derived wing vein specification GO:0007474 48 0.019
positive regulation of cellular biosynthetic process GO:0031328 316 0.019
molting cycle GO:0042303 56 0.019
purine nucleoside triphosphate catabolic process GO:0009146 108 0.019
cellular component assembly involved in morphogenesis GO:0010927 151 0.019
dna amplification GO:0006277 11 0.019
appendage morphogenesis GO:0035107 397 0.019
spindle elongation GO:0051231 83 0.018
nuclear division GO:0000280 332 0.018
meiotic chromosome segregation GO:0045132 59 0.018
multicellular organism growth GO:0035264 46 0.018
purine nucleoside triphosphate metabolic process GO:0009144 119 0.018
protein phosphorylation GO:0006468 169 0.018
ribonucleoside monophosphate catabolic process GO:0009158 39 0.018
spermatid development GO:0007286 98 0.017
positive regulation of phosphorus metabolic process GO:0010562 139 0.017
purine ribonucleotide catabolic process GO:0009154 109 0.017
nucleoside metabolic process GO:0009116 127 0.017
carbohydrate derivative catabolic process GO:1901136 118 0.017
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.017
imaginal disc derived wing hair organization GO:0035317 45 0.017
ribonucleoside metabolic process GO:0009119 127 0.017
germarium derived female germ line cyst formation GO:0030727 42 0.017
positive regulation of catabolic process GO:0009896 105 0.016
snrna 3 end processing GO:0034472 14 0.016
ribonucleoside monophosphate metabolic process GO:0009161 51 0.016
nucleoside phosphate catabolic process GO:1901292 110 0.016
regulation of protein modification process GO:0031399 112 0.016
asymmetric cell division GO:0008356 37 0.016
organonitrogen compound catabolic process GO:1901565 128 0.016
microtubule based movement GO:0007018 51 0.016
neuron projection guidance GO:0097485 241 0.016
positive regulation of gene expression GO:0010628 290 0.015
kinetochore organization GO:0051383 9 0.015
nucleoside triphosphate metabolic process GO:0009141 120 0.015
microtubule organizing center organization GO:0031023 168 0.015
response to organic substance GO:0010033 284 0.015
purine nucleoside monophosphate catabolic process GO:0009128 38 0.015
protein modification by small protein conjugation GO:0032446 79 0.015
positive regulation of signaling GO:0023056 243 0.015
negative regulation of microtubule polymerization or depolymerization GO:0031111 21 0.014
rna 3 end processing GO:0031123 45 0.014
purine ribonucleoside catabolic process GO:0046130 112 0.014
eye morphogenesis GO:0048592 260 0.014
positive regulation of molecular function GO:0044093 136 0.014
immune system process GO:0002376 347 0.014
actin cytoskeleton organization GO:0030036 206 0.014
negative regulation of protein metabolic process GO:0051248 85 0.014
regulation of chromosome segregation GO:0051983 32 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.014
positive regulation of protein metabolic process GO:0051247 128 0.014
regulation of ras protein signal transduction GO:0046578 93 0.014
appendage development GO:0048736 401 0.014
regulation of cell shape GO:0008360 113 0.014
regulation of catalytic activity GO:0050790 185 0.014
meiotic cytokinesis GO:0033206 33 0.014
purine nucleoside catabolic process GO:0006152 112 0.014
compound eye photoreceptor cell differentiation GO:0001751 140 0.014
nuclear transcribed mrna catabolic process GO:0000956 24 0.013
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.013
endomembrane system organization GO:0010256 119 0.013
glycosyl compound metabolic process GO:1901657 127 0.013
leg disc development GO:0035218 92 0.013
membrane organization GO:0061024 112 0.013
biological adhesion GO:0022610 138 0.013
post embryonic appendage morphogenesis GO:0035120 385 0.013
imaginal disc derived leg morphogenesis GO:0007480 80 0.013
regulation of sister chromatid segregation GO:0033045 28 0.013
cell death GO:0008219 279 0.013
microtubule bundle formation GO:0001578 27 0.013
spermatid differentiation GO:0048515 114 0.013
positive regulation of biosynthetic process GO:0009891 316 0.013
compound eye photoreceptor development GO:0042051 78 0.013
positive regulation of signal transduction GO:0009967 223 0.013
spindle midzone assembly GO:0051255 4 0.013
larval development GO:0002164 104 0.013
regulation of growth GO:0040008 233 0.013
hair cell differentiation GO:0035315 47 0.012
negative regulation of catabolic process GO:0009895 36 0.012
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.012
regulation of protein processing GO:0070613 32 0.012
response to fungus GO:0009620 50 0.012
apoptotic process GO:0006915 159 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.012
regulation of cellular protein catabolic process GO:1903362 44 0.012
neuron remodeling GO:0016322 29 0.012
metaphase plate congression GO:0051310 19 0.012
signal transduction by phosphorylation GO:0023014 107 0.012
negative regulation of homeostatic process GO:0032845 2 0.012
chorion containing eggshell formation GO:0007304 105 0.012
somatic muscle development GO:0007525 66 0.012
regulation of proteolysis GO:0030162 87 0.011
regulation of cell morphogenesis GO:0022604 163 0.011
response to abiotic stimulus GO:0009628 341 0.011
snrna metabolic process GO:0016073 14 0.011
regulation of cellular catabolic process GO:0031329 157 0.011
negative regulation of translation GO:0017148 28 0.011
ribonucleoside catabolic process GO:0042454 112 0.011
atp catabolic process GO:0006200 38 0.011
forebrain development GO:0030900 2 0.011
regulation of erk1 and erk2 cascade GO:0070372 39 0.011
rna processing GO:0006396 147 0.011
regulation of notch signaling pathway GO:0008593 100 0.011
nucleoside monophosphate metabolic process GO:0009123 52 0.011
protein localization GO:0008104 284 0.011
single organism membrane organization GO:0044802 93 0.011
positive regulation of cell communication GO:0010647 250 0.010
establishment of tissue polarity GO:0007164 87 0.010
death GO:0016265 284 0.010
male meiosis GO:0007140 52 0.010
neuroblast proliferation GO:0007405 74 0.010
gonad development GO:0008406 50 0.010
response to monosaccharide GO:0034284 4 0.010
cellular protein localization GO:0034613 160 0.010
negative regulation of protein depolymerization GO:1901880 23 0.010
negative regulation of microtubule depolymerization GO:0007026 21 0.010

DNApol-alpha180 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org