Drosophila melanogaster

93 known processes

psh (Dmel_CG6367)

persephone

(Aliases: CG6367,c-SP28,Psh,SP28,Dmel\CG6367)

psh biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
peptide metabolic process GO:0006518 80 0.533
response to external biotic stimulus GO:0043207 293 0.500
cellular amide metabolic process GO:0043603 80 0.383
response to biotic stimulus GO:0009607 294 0.341
defense response to other organism GO:0098542 225 0.324
defense response GO:0006952 300 0.258
immune response GO:0006955 246 0.255
immune system process GO:0002376 347 0.242
regulation of humoral immune response GO:0002920 51 0.208
regulation of biosynthetic process of antibacterial peptides active against gram positive bacteria GO:0002816 3 0.194
organonitrogen compound metabolic process GO:1901564 318 0.182
defense response to bacterium GO:0042742 178 0.180
regulation of antimicrobial humoral response GO:0002759 50 0.158
production of molecular mediator of immune response GO:0002440 46 0.154
antimicrobial humoral response GO:0019730 99 0.152
response to other organism GO:0051707 293 0.152
regulation of immune effector process GO:0002697 52 0.147
regionalization GO:0003002 416 0.141
response to bacterium GO:0009617 198 0.140
regulation of antimicrobial peptide production GO:0002784 44 0.140
positive regulation of response to external stimulus GO:0032103 44 0.122
toll signaling pathway GO:0008063 25 0.115
regulation of multi organism process GO:0043900 131 0.108
negative regulation of peptidoglycan recognition protein signaling pathway GO:0061060 3 0.106
innate immune response GO:0045087 144 0.105
regulation of cellular amide metabolic process GO:0034248 39 0.101
response to fungus GO:0009620 50 0.100
antimicrobial peptide production GO:0002775 46 0.097
immune effector process GO:0002252 98 0.095
antimicrobial peptide biosynthetic process GO:0002777 38 0.093
immune response activating signal transduction GO:0002757 2 0.093
pattern recognition receptor signaling pathway GO:0002221 2 0.091
activation of innate immune response GO:0002218 4 0.087
biosynthetic process of antibacterial peptides active against gram positive bacteria GO:0002815 3 0.081
negative regulation of cellular metabolic process GO:0031324 382 0.081
innate immune response activating signal transduction GO:0002758 2 0.080
regulation of response to biotic stimulus GO:0002831 63 0.076
defense response to gram positive bacterium GO:0050830 41 0.074
regulation of production of molecular mediator of immune response GO:0002700 44 0.073
negative regulation of signaling GO:0023057 219 0.073
regulation of peptidoglycan recognition protein signaling pathway GO:0061058 4 0.071
regulation of defense response GO:0031347 102 0.071
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.071
defense response to fungus GO:0050832 48 0.069
negative regulation of signal transduction GO:0009968 206 0.068
regulation of response to external stimulus GO:0032101 115 0.066
humoral immune response GO:0006959 117 0.066
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.064
regulation of antimicrobial peptide biosynthetic process GO:0002805 38 0.063
defense response to gram negative bacterium GO:0050829 94 0.062
melanin metabolic process GO:0006582 47 0.061
Fly
dorsal ventral axis specification GO:0009950 66 0.058
positive regulation of biosynthetic process GO:0009891 316 0.058
positive regulation of antimicrobial peptide production GO:0002225 28 0.057
peptidoglycan metabolic process GO:0000270 3 0.057
protein maturation GO:0051604 71 0.057
negative regulation of response to external stimulus GO:0032102 22 0.057
antifungal humoral response GO:0019732 12 0.057
regulation of response to stress GO:0080134 200 0.056
proteolysis GO:0006508 192 0.055
biosynthetic process of antibacterial peptides active against gram negative bacteria GO:0002812 14 0.055
positive regulation of biosynthetic process of antibacterial peptides active against gram positive bacteria GO:0006965 3 0.054
positive regulation of melanization defense response GO:0035008 1 0.054
melanization defense response GO:0035006 45 0.054
Fly
regulation of immune system process GO:0002682 176 0.053
positive regulation of response to stimulus GO:0048584 323 0.053
response to organic substance GO:0010033 284 0.052
organic hydroxy compound metabolic process GO:1901615 83 0.052
Fly
positive regulation of antimicrobial peptide biosynthetic process GO:0002807 26 0.052
catabolic process GO:0009056 409 0.051
antibacterial humoral response GO:0019731 44 0.051
response to lipopolysaccharide GO:0032496 4 0.051
positive regulation of multi organism process GO:0043902 40 0.050
phenol containing compound metabolic process GO:0018958 57 0.050
Fly
small molecule metabolic process GO:0044281 305 0.050
positive regulation of humoral immune response GO:0002922 28 0.050
imaginal disc derived wing morphogenesis GO:0007476 337 0.049
amide biosynthetic process GO:0043604 42 0.049
negative regulation of response to stimulus GO:0048585 258 0.049
pigment metabolic process GO:0042440 84 0.048
Fly
appendage morphogenesis GO:0035107 397 0.047
imaginal disc derived appendage morphogenesis GO:0035114 395 0.047
positive regulation of response to biotic stimulus GO:0002833 31 0.046
positive regulation of signaling GO:0023056 243 0.045
regulation of toll signaling pathway GO:0008592 17 0.045
response to peptidoglycan GO:0032494 2 0.045
negative regulation of cell communication GO:0010648 223 0.045
axis specification GO:0009798 167 0.044
phosphorylation GO:0016310 294 0.043
regulation of innate immune response GO:0045088 71 0.042
Fly
positive regulation of cell communication GO:0010647 250 0.042
negative regulation of peptide hormone processing GO:0060570 1 0.041
response to abiotic stimulus GO:0009628 341 0.041
endocytosis GO:0006897 310 0.041
regulation of immune response GO:0050776 118 0.040
antibacterial peptide production GO:0002778 22 0.039
appendage development GO:0048736 401 0.039
intracellular signal transduction GO:0035556 300 0.039
organonitrogen compound biosynthetic process GO:1901566 117 0.039
immune response regulating signaling pathway GO:0002764 2 0.038
developmental growth GO:0048589 280 0.038
negative regulation of defense response GO:0031348 35 0.038
organic substance catabolic process GO:1901575 308 0.038
post embryonic appendage morphogenesis GO:0035120 385 0.037
positive regulation of antimicrobial humoral response GO:0002760 28 0.037
cellular amino acid metabolic process GO:0006520 61 0.037
carbohydrate derivative metabolic process GO:1901135 217 0.037
negative regulation of gene expression GO:0010629 387 0.037
wing disc morphogenesis GO:0007472 344 0.037
compound eye development GO:0048749 307 0.036
regulation of antibacterial peptide production GO:0002786 22 0.036
peptidoglycan catabolic process GO:0009253 3 0.035
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.035
imaginal disc derived appendage development GO:0048737 399 0.034
response to wounding GO:0009611 94 0.034
negative regulation of defense response to bacterium GO:1900425 7 0.034
regulation of biosynthetic process of antibacterial peptides active against gram negative bacteria GO:0002813 14 0.034
antibacterial peptide biosynthetic process GO:0002780 22 0.034
positive regulation of antibacterial peptide production GO:0002803 20 0.034
biological adhesion GO:0022610 138 0.033
oxoacid metabolic process GO:0043436 103 0.033
macromolecule catabolic process GO:0009057 161 0.033
organelle fission GO:0048285 340 0.033
vesicle mediated transport GO:0016192 381 0.032
cellular catabolic process GO:0044248 372 0.032
regulation of intracellular signal transduction GO:1902531 236 0.032
regulation of antibacterial peptide biosynthetic process GO:0002808 22 0.032
dorsal ventral pattern formation GO:0009953 133 0.031
mapk cascade GO:0000165 107 0.030
growth GO:0040007 359 0.030
wound healing GO:0042060 75 0.030
spermatogenesis GO:0007283 200 0.029
secondary metabolic process GO:0019748 75 0.029
Fly
positive regulation of signal transduction GO:0009967 223 0.029
response to oxygen containing compound GO:1901700 200 0.028
protein modification process GO:0036211 438 0.028
response to endogenous stimulus GO:0009719 119 0.028
organic substance transport GO:0071702 257 0.027
cell cell signaling involved in cell fate commitment GO:0045168 210 0.027
regulation of molecular function GO:0065009 217 0.027
cell death GO:0008219 279 0.027
response to extracellular stimulus GO:0009991 116 0.027
single organism biosynthetic process GO:0044711 206 0.026
carboxylic acid metabolic process GO:0019752 92 0.026
cellular response to molecule of bacterial origin GO:0071219 3 0.026
regulation of transport GO:0051049 181 0.026
hormone catabolic process GO:0042447 3 0.026
positive regulation of cellular biosynthetic process GO:0031328 316 0.026
stress activated mapk cascade GO:0051403 52 0.026
regulation of localization GO:0032879 275 0.026
protein processing GO:0016485 68 0.025
cellular response to lipopolysaccharide GO:0071222 3 0.025
steroid catabolic process GO:0006706 1 0.024
regulation of cellular protein metabolic process GO:0032268 243 0.024
signal transduction by phosphorylation GO:0023014 107 0.024
response to nitrogen compound GO:1901698 90 0.024
eye development GO:0001654 323 0.023
positive regulation of biosynthetic process of antibacterial peptides active against gram negative bacteria GO:0006964 12 0.023
cellular amine metabolic process GO:0044106 12 0.023
epithelial cell differentiation GO:0030855 322 0.023
negative regulation of immune system process GO:0002683 50 0.023
chromosome segregation GO:0007059 157 0.023
cellular protein modification process GO:0006464 438 0.023
multicellular organismal aging GO:0010259 140 0.023
mating GO:0007618 120 0.023
compound eye morphogenesis GO:0001745 249 0.022
response to organophosphorus GO:0046683 2 0.022
sensory organ morphogenesis GO:0090596 260 0.022
response to nutrient levels GO:0031667 114 0.022
regulation of phosphorus metabolic process GO:0051174 210 0.022
phagocytosis GO:0006909 215 0.022
glycosaminoglycan catabolic process GO:0006027 3 0.022
positive regulation of defense response GO:0031349 59 0.022
amine metabolic process GO:0009308 12 0.022
eye morphogenesis GO:0048592 260 0.021
establishment of localization in cell GO:0051649 402 0.021
positive regulation of immune system process GO:0002684 68 0.021
macromolecular complex assembly GO:0065003 256 0.021
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.021
positive regulation of immune response GO:0050778 63 0.021
organonitrogen compound catabolic process GO:1901565 128 0.021
positive regulation of antibacterial peptide biosynthetic process GO:0006963 20 0.021
cell motility GO:0048870 251 0.021
hemolymph coagulation GO:0042381 10 0.021
cellular response to organic substance GO:0071310 132 0.020
pigmentation GO:0043473 75 0.020
regulation of melanization defense response GO:0035007 6 0.020
Fly
cellular response to chemical stimulus GO:0070887 199 0.020
negative regulation of immune response GO:0050777 39 0.020
regulation of phosphorylation GO:0042325 147 0.020
peptide biosynthetic process GO:0043043 42 0.020
regulation of proteolysis GO:0030162 87 0.020
mating behavior GO:0007617 106 0.019
stress activated protein kinase signaling cascade GO:0031098 55 0.019
androgen metabolic process GO:0008209 1 0.019
homeostatic process GO:0042592 199 0.019
developmental pigmentation GO:0048066 68 0.019
cellular response to biotic stimulus GO:0071216 4 0.019
aromatic compound catabolic process GO:0019439 166 0.019
monocarboxylic acid transport GO:0015718 3 0.019
regulation of defense response to bacterium GO:1900424 30 0.019
death GO:0016265 284 0.019
protein localization GO:0008104 284 0.019
localization of cell GO:0051674 257 0.019
body morphogenesis GO:0010171 2 0.019
aminoglycan metabolic process GO:0006022 18 0.018
single organism behavior GO:0044708 391 0.018
cell migration GO:0016477 238 0.018
determination of adult lifespan GO:0008340 137 0.018
single organism catabolic process GO:0044712 228 0.018
regulation of cell cycle GO:0051726 291 0.018
eye pigment biosynthetic process GO:0006726 32 0.018
negative regulation of innate immune response GO:0045824 30 0.018
nucleobase containing small molecule metabolic process GO:0055086 174 0.018
negative regulation of biosynthetic process GO:0009890 277 0.017
negative regulation of phosphorus metabolic process GO:0010563 45 0.017
nuclear division GO:0000280 332 0.017
response to organic cyclic compound GO:0014070 89 0.017
positive regulation of production of molecular mediator of immune response GO:0002702 28 0.017
salivary gland histolysis GO:0035070 88 0.017
regulation of stress activated mapk cascade GO:0032872 41 0.017
choline catabolic process GO:0042426 1 0.017
embryonic pattern specification GO:0009880 174 0.016
salivary gland development GO:0007431 162 0.016
regulation of hydrolase activity GO:0051336 97 0.016
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.016
lateral inhibition GO:0046331 206 0.016
positive regulation of cell motility GO:2000147 3 0.016
defense response to virus GO:0051607 23 0.016
glycosyl compound metabolic process GO:1901657 127 0.016
regulation of cellular ketone metabolic process GO:0010565 3 0.016
organophosphate metabolic process GO:0019637 195 0.016
columnar cuboidal epithelial cell development GO:0002066 249 0.016
response to radiation GO:0009314 155 0.016
negative regulation of cellular protein metabolic process GO:0032269 85 0.016
regulation of cellular amine metabolic process GO:0033238 3 0.016
endomembrane system organization GO:0010256 119 0.016
positive regulation of defense response to bacterium GO:1900426 23 0.016
positive regulation of cell migration GO:0030335 2 0.016
forebrain development GO:0030900 2 0.015
cell adhesion GO:0007155 136 0.015
multi organism behavior GO:0051705 175 0.015
regulation of catalytic activity GO:0050790 185 0.015
cellular ketone metabolic process GO:0042180 24 0.015
negative regulation of phosphate metabolic process GO:0045936 45 0.015
salivary gland morphogenesis GO:0007435 145 0.015
neuron recognition GO:0008038 101 0.015
axon development GO:0061564 297 0.015
developmental programmed cell death GO:0010623 138 0.015
morphogenesis of an epithelium GO:0002009 276 0.015
lipid metabolic process GO:0006629 121 0.015
regulation of mapk cascade GO:0043408 92 0.015
response to temperature stimulus GO:0009266 106 0.015
ethanolamine containing compound metabolic process GO:0042439 4 0.015
acetylcholine metabolic process GO:0008291 2 0.015
actin filament based process GO:0030029 220 0.015
cell proliferation GO:0008283 299 0.015
epithelial cell migration GO:0010631 148 0.015
intracellular transport GO:0046907 228 0.015
regulation of cell death GO:0010941 173 0.015
synaptic transmission GO:0007268 288 0.015
chemotaxis GO:0006935 249 0.015
carbohydrate derivative catabolic process GO:1901136 118 0.015
regulation of secondary metabolic process GO:0043455 7 0.014
Fly
kidney development GO:0001822 3 0.014
regulation of organelle organization GO:0033043 196 0.014
jnk cascade GO:0007254 50 0.014
spermatid differentiation GO:0048515 114 0.014
positive regulation of catalytic activity GO:0043085 118 0.014
cellular homeostasis GO:0019725 80 0.014
eye pigmentation GO:0048069 43 0.014
glycosaminoglycan metabolic process GO:0030203 11 0.014
positive regulation of cellular amide metabolic process GO:0034250 26 0.014
connective tissue development GO:0061448 3 0.014
open tracheal system development GO:0007424 204 0.014
response to light stimulus GO:0009416 124 0.014
pigment metabolic process involved in developmental pigmentation GO:0043324 33 0.014
gland morphogenesis GO:0022612 145 0.014
cellularization GO:0007349 90 0.014
heterocycle catabolic process GO:0046700 166 0.014
negative regulation of protein metabolic process GO:0051248 85 0.014
negative regulation of rna metabolic process GO:0051253 251 0.014
taxis GO:0042330 304 0.014
cellular response to dna damage stimulus GO:0006974 223 0.014
pigment biosynthetic process GO:0046148 36 0.014
organelle assembly GO:0070925 198 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.013
regulation of protein metabolic process GO:0051246 256 0.013
protein complex biogenesis GO:0070271 201 0.013
positive regulation of innate immune response GO:0045089 38 0.013
mitotic nuclear division GO:0007067 213 0.013
negative regulation of phosphorylation GO:0042326 35 0.013
detection of abiotic stimulus GO:0009582 66 0.013
border follicle cell migration GO:0007298 113 0.013
negative regulation of cellular biosynthetic process GO:0031327 277 0.013
programmed cell death GO:0012501 257 0.013
drinking behavior GO:0042756 2 0.013
zymogen activation GO:0031638 20 0.013
ameboidal type cell migration GO:0001667 151 0.013
gland development GO:0048732 191 0.013
gene silencing GO:0016458 138 0.013
regulation of cell proliferation GO:0042127 163 0.013
phagocytosis recognition GO:0006910 1 0.013
cation homeostasis GO:0055080 51 0.013
central nervous system development GO:0007417 201 0.013
negative regulation of stress activated protein kinase signaling cascade GO:0070303 20 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.013
hormone metabolic process GO:0042445 33 0.013
aminoglycan catabolic process GO:0006026 6 0.013
multi multicellular organism process GO:0044706 123 0.013
protein phosphorylation GO:0006468 169 0.013
regulation of endopeptidase activity GO:0052548 36 0.013
segmentation GO:0035282 207 0.013
ovarian follicle cell development GO:0030707 248 0.013
reproductive behavior GO:0019098 122 0.013
cell adhesion involved in heart morphogenesis GO:0061343 12 0.013
positive regulation of intracellular signal transduction GO:1902533 116 0.013
establishment of protein localization GO:0045184 163 0.012
purine nucleoside metabolic process GO:0042278 127 0.012
autophagic cell death GO:0048102 83 0.012
negative regulation of multi organism process GO:0043901 29 0.012
single organism intracellular transport GO:1902582 207 0.012
embryonic development via the syncytial blastoderm GO:0001700 148 0.012
adult behavior GO:0030534 137 0.012
regulation of cellular component biogenesis GO:0044087 201 0.012
sterol homeostasis GO:0055092 4 0.012
positive regulation of molecular function GO:0044093 136 0.012
regulation of cell adhesion GO:0030155 27 0.012
organic cyclic compound catabolic process GO:1901361 168 0.012
ribonucleoside metabolic process GO:0009119 127 0.012
cholesterol homeostasis GO:0042632 3 0.012
ovarian follicle cell migration GO:0007297 121 0.012
cell cell junction organization GO:0045216 55 0.012
male gamete generation GO:0048232 201 0.012
negative regulation of cell death GO:0060548 81 0.012
amine catabolic process GO:0009310 1 0.012
regulation of cellular localization GO:0060341 136 0.012
acetate ester metabolic process GO:1900619 2 0.012
detection of stimulus GO:0051606 156 0.012
actin cytoskeleton organization GO:0030036 206 0.012
telencephalon development GO:0021537 2 0.012
response to organonitrogen compound GO:0010243 75 0.012
response to lipid GO:0033993 38 0.012
negative regulation of mapk cascade GO:0043409 23 0.012
meiotic cell cycle process GO:1903046 132 0.011
chromosome organization GO:0051276 360 0.011
regulation of cell differentiation GO:0045595 302 0.011
negative regulation of molecular function GO:0044092 51 0.011
chaeta development GO:0022416 97 0.011
salivary gland cell autophagic cell death GO:0035071 83 0.011
response to virus GO:0009615 28 0.011
spindle organization GO:0007051 253 0.011
negative regulation of rna biosynthetic process GO:1902679 240 0.011
positive regulation of immune effector process GO:0002699 28 0.011
meiotic cell cycle GO:0051321 171 0.011
small gtpase mediated signal transduction GO:0007264 88 0.011
negative regulation of intracellular signal transduction GO:1902532 57 0.011
exocrine system development GO:0035272 162 0.011
positive regulation of catabolic process GO:0009896 105 0.011
sulfur compound metabolic process GO:0006790 59 0.011
negative regulation of cell differentiation GO:0045596 143 0.011
axonogenesis GO:0007409 290 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.011
regulation of cellular catabolic process GO:0031329 157 0.011
meiotic chromosome segregation GO:0045132 59 0.011
cellular response to oxygen containing compound GO:1901701 79 0.011
nucleoside metabolic process GO:0009116 127 0.011
glutathione metabolic process GO:0006749 37 0.011
rna processing GO:0006396 147 0.011
ras protein signal transduction GO:0007265 88 0.011
tissue death GO:0016271 102 0.011
secretion GO:0046903 109 0.011
positive regulation of cellular catabolic process GO:0031331 95 0.011
response to hexose GO:0009746 3 0.011
regulation of multicellular organismal development GO:2000026 414 0.011
regulation of programmed cell death GO:0043067 152 0.011
positive regulation of phosphorus metabolic process GO:0010562 139 0.011
peptide hormone processing GO:0016486 2 0.011
acid secretion GO:0046717 1 0.011
transcription from rna polymerase ii promoter GO:0006366 368 0.011
regulation of catabolic process GO:0009894 170 0.011
apoptotic process GO:0006915 159 0.011
camera type eye development GO:0043010 4 0.011
protein transport GO:0015031 155 0.011
peptidoglycan recognition protein signaling pathway GO:0061057 16 0.011
positive regulation of macromolecule metabolic process GO:0010604 405 0.011
neurotransmitter metabolic process GO:0042133 2 0.011
epithelium migration GO:0090132 148 0.011
cell recognition GO:0008037 102 0.011
cell cell junction assembly GO:0007043 38 0.011
protein complex assembly GO:0006461 200 0.010
retina development in camera type eye GO:0060041 4 0.010
camera type eye morphogenesis GO:0048593 2 0.010
dna metabolic process GO:0006259 227 0.010
cellular response to lipid GO:0071396 20 0.010
regulation of anatomical structure size GO:0090066 163 0.010
actin filament organization GO:0007015 126 0.010
ommochrome biosynthetic process GO:0006727 19 0.010
single organism cellular localization GO:1902580 180 0.010
nucleoside phosphate metabolic process GO:0006753 162 0.010
mitotic spindle organization GO:0007052 220 0.010
autophagy GO:0006914 108 0.010
negative regulation of nucleic acid templated transcription GO:1903507 240 0.010
response to copper ion GO:0046688 4 0.010
histolysis GO:0007559 102 0.010
positive regulation of transport GO:0051050 92 0.010
multicellular organismal reproductive behavior GO:0033057 110 0.010
regulation of hormone levels GO:0010817 40 0.010
nucleotide metabolic process GO:0009117 161 0.010
peripheral nervous system development GO:0007422 52 0.010
ion transport GO:0006811 145 0.010
positive regulation of phosphate metabolic process GO:0045937 139 0.010
chemical homeostasis GO:0048878 92 0.010

psh disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.027
disease of metabolism DOID:0014667 0 0.020
inherited metabolic disorder DOID:655 0 0.015
nervous system disease DOID:863 0 0.013
central nervous system disease DOID:331 0 0.010