Drosophila melanogaster

275 known processes

crb (Dmel_CG6383)

crumbs

(Aliases: CRB,crumb,Dmel\CG6383,0509/20,far,Crb,Crbs,1384/04,CG6383,l(3)S058104,Crumbs,l(3)j1B5,l(3)S050920,CT19912,l(3)07207)

crb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
compound eye morphogenesis GO:0001745 249 0.999
compound eye photoreceptor development GO:0042051 78 0.999
eye photoreceptor cell development GO:0042462 81 0.998
embryonic morphogenesis GO:0048598 206 0.995
axis specification GO:0009798 167 0.991
establishment or maintenance of bipolar cell polarity GO:0061245 34 0.989
eye photoreceptor cell differentiation GO:0001754 145 0.989
cell junction organization GO:0034330 57 0.988
tube development GO:0035295 244 0.986
compound eye photoreceptor cell differentiation GO:0001751 140 0.985
epithelial cell development GO:0002064 274 0.983
tube morphogenesis GO:0035239 191 0.980
morphogenesis of an epithelium GO:0002009 276 0.955
membrane organization GO:0061024 112 0.950
imaginal disc derived appendage morphogenesis GO:0035114 395 0.945
ommatidial rotation GO:0016318 20 0.944
photoreceptor cell differentiation GO:0046530 170 0.941
regulation of cell morphogenesis GO:0022604 163 0.929
blastoderm segmentation GO:0007350 159 0.917
photoreceptor cell development GO:0042461 96 0.910
adherens junction organization GO:0034332 27 0.906
regulation of cell shape GO:0008360 113 0.902
embryonic organ development GO:0048568 50 0.900
apical constriction GO:0003383 18 0.896
post embryonic appendage morphogenesis GO:0035120 385 0.892
compound eye development GO:0048749 307 0.892
cell projection assembly GO:0030031 94 0.890
embryonic pattern specification GO:0009880 174 0.886
establishment of protein localization to plasma membrane GO:0090002 9 0.886
organelle localization GO:0051640 148 0.881
eye morphogenesis GO:0048592 260 0.881
establishment of planar polarity GO:0001736 87 0.874
pericardium morphogenesis GO:0003344 2 0.873
single organism membrane organization GO:0044802 93 0.858
morphogenesis of a polarized epithelium GO:0001738 93 0.855
establishment of ommatidial planar polarity GO:0042067 49 0.853
appendage development GO:0048736 401 0.849
regulation of anatomical structure size GO:0090066 163 0.841
adherens junction assembly GO:0034333 11 0.840
digestive tract morphogenesis GO:0048546 127 0.838
eye development GO:0001654 323 0.829
regulation of tube size open tracheal system GO:0035151 43 0.825
digestive system development GO:0055123 149 0.824
morphogenesis of embryonic epithelium GO:0016331 94 0.820
single organism cellular localization GO:1902580 180 0.797
morphogenesis of a branching structure GO:0001763 45 0.792
regulation of tube architecture open tracheal system GO:0035152 68 0.791
appendage morphogenesis GO:0035107 397 0.791
epithelial cell differentiation GO:0030855 322 0.778
establishment of tissue polarity GO:0007164 87 0.777
embryo development ending in birth or egg hatching GO:0009792 152 0.748
filopodium assembly GO:0046847 33 0.726
fusion cell fate specification GO:0035156 4 0.718
establishment or maintenance of apical basal cell polarity GO:0035088 34 0.699
regulation of organ morphogenesis GO:2000027 78 0.689
eggshell chorion assembly GO:0007306 66 0.682
r3 r4 cell differentiation GO:0048056 12 0.670
rhabdomere development GO:0042052 38 0.667
cell junction assembly GO:0034329 42 0.665
ovarian follicle cell migration GO:0007297 121 0.652
hemocyte migration GO:0035099 19 0.649
sensory organ morphogenesis GO:0090596 260 0.648
regulation of embryonic development GO:0045995 68 0.648
regulation of multicellular organismal development GO:2000026 414 0.645
asymmetric protein localization GO:0008105 33 0.642
canonical wnt signaling pathway involved in heart development GO:0061316 3 0.636
wing disc morphogenesis GO:0007472 344 0.615
imaginal disc derived appendage development GO:0048737 399 0.609
dorsal closure GO:0007391 79 0.609
single organism behavior GO:0044708 391 0.598
establishment or maintenance of monopolar cell polarity GO:0061339 15 0.597
plasma membrane organization GO:0007009 26 0.594
digestive tract development GO:0048565 149 0.577
rhythmic process GO:0048511 106 0.565
regionalization GO:0003002 416 0.565
protein localization to plasma membrane GO:0072659 13 0.564
regulation of malpighian tubule diameter GO:0035297 3 0.564
regulation of filopodium assembly GO:0051489 24 0.560
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 24 0.545
cytoplasmic transport GO:0016482 130 0.544
neurological system process GO:0050877 358 0.541
single organism cell adhesion GO:0098602 47 0.539
head development GO:0060322 135 0.534
growth GO:0040007 359 0.530
extracellular structure organization GO:0043062 46 0.513
negative regulation of cell cell adhesion GO:0022408 8 0.513
r3 r4 cell fate commitment GO:0007464 10 0.503
mesenchyme development GO:0060485 9 0.500
zonula adherens assembly GO:0045186 6 0.500
cell cell junction organization GO:0045216 55 0.495
cell matrix adhesion GO:0007160 6 0.491
cell adhesion GO:0007155 136 0.487
protein modification process GO:0036211 438 0.484
apical junction assembly GO:0043297 32 0.479
embryonic axis specification GO:0000578 107 0.477
chorion containing eggshell formation GO:0007304 105 0.467
cell division GO:0051301 248 0.464
gastrulation involving germ band extension GO:0010004 36 0.460
tissue morphogenesis GO:0048729 297 0.454
negative regulation of developmental growth GO:0048640 64 0.452
localization of cell GO:0051674 257 0.452
regulation of cell differentiation GO:0045595 302 0.447
dorsal closure elongation of leading edge cells GO:0007394 10 0.445
gliogenesis GO:0042063 80 0.445
oocyte development GO:0048599 124 0.445
open tracheal system development GO:0007424 204 0.441
establishment of epithelial cell apical basal polarity GO:0045198 10 0.440
cell type specific apoptotic process GO:0097285 38 0.438
regulation of embryonic cell shape GO:0016476 30 0.432
heart field specification GO:0003128 0 0.428
developmental programmed cell death GO:0010623 138 0.428
axon development GO:0061564 297 0.426
reproductive system development GO:0061458 74 0.424
axon guidance GO:0007411 233 0.418
transcription from rna polymerase ii promoter GO:0006366 368 0.410
epidermis development GO:0008544 65 0.402
tripartite regional subdivision GO:0007351 103 0.401
pole plasm rna localization GO:0007316 52 0.399
dorsal appendage formation GO:0046843 47 0.393
respiratory system development GO:0060541 213 0.393
anterior posterior axis specification embryo GO:0008595 103 0.392
neuron projection guidance GO:0097485 241 0.386
chemotaxis GO:0006935 249 0.385
nuclear transport GO:0051169 72 0.370
spermatogenesis GO:0007283 200 0.369
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.366
oocyte differentiation GO:0009994 145 0.363
cell cell signaling involved in cell fate commitment GO:0045168 210 0.362
cortical actin cytoskeleton organization GO:0030866 24 0.360
establishment of apical basal cell polarity GO:0035089 12 0.359
apoptotic process involved in development GO:1902742 20 0.356
biological adhesion GO:0022610 138 0.354
forebrain development GO:0030900 2 0.354
eye antennal disc morphogenesis GO:0007455 34 0.350
cell cell junction assembly GO:0007043 38 0.349
eggshell formation GO:0030703 105 0.346
epithelial cell morphogenesis GO:0003382 25 0.344
establishment or maintenance of cell polarity GO:0007163 167 0.337
regulation of establishment of planar polarity GO:0090175 22 0.337
pole plasm mrna localization GO:0019094 49 0.334
cell recognition GO:0008037 102 0.334
regulation of cell development GO:0060284 215 0.333
kidney development GO:0001822 3 0.332
planar cell polarity pathway involved in axis elongation GO:0003402 3 0.329
cell migration GO:0016477 238 0.329
body morphogenesis GO:0010171 2 0.326
nucleocytoplasmic transport GO:0006913 72 0.322
malpighian tubule development GO:0072002 64 0.322
regulation of tube length open tracheal system GO:0035159 24 0.322
delamination GO:0060232 8 0.318
negative regulation of cell differentiation GO:0045596 143 0.318
cell substrate adhesion GO:0031589 10 0.313
oocyte construction GO:0007308 112 0.312
establishment of localization in cell GO:0051649 402 0.309
border follicle cell migration GO:0007298 113 0.309
compound eye cone cell fate commitment GO:0042676 5 0.306
imaginal disc derived wing morphogenesis GO:0007476 337 0.304
regulation of cell cell adhesion GO:0022407 21 0.304
segmentation GO:0035282 207 0.304
developmental growth involved in morphogenesis GO:0060560 65 0.301
genitalia morphogenesis GO:0035112 16 0.299
asymmetric protein localization involved in cell fate determination GO:0045167 9 0.295
pole plasm assembly GO:0007315 61 0.293
synaptic transmission GO:0007268 288 0.289
germarium derived female germ line cyst formation GO:0030727 42 0.281
wnt signaling pathway planar cell polarity pathway GO:0060071 6 0.278
oocyte anterior posterior axis specification GO:0007314 72 0.278
locomotory behavior GO:0007626 176 0.276
spindle organization GO:0007051 253 0.274
male gamete generation GO:0048232 201 0.271
renal tubule development GO:0061326 64 0.265
regulation of anatomical structure morphogenesis GO:0022603 242 0.260
heart development GO:0007507 82 0.259
germarium derived oocyte fate determination GO:0007294 26 0.257
anterior posterior axis specification GO:0009948 109 0.254
regulation of rho protein signal transduction GO:0035023 20 0.253
taxis GO:0042330 304 0.248
urogenital system development GO:0001655 72 0.248
syncytium formation GO:0006949 43 0.247
cellular protein localization GO:0034613 160 0.241
actin filament based process GO:0030029 220 0.236
positive regulation of protein localization to plasma membrane GO:1903078 3 0.234
axonogenesis GO:0007409 290 0.232
syncytium formation by plasma membrane fusion GO:0000768 43 0.231
rho protein signal transduction GO:0007266 14 0.231
muscle organ development GO:0007517 127 0.231
positive regulation of macromolecule metabolic process GO:0010604 405 0.230
receptor clustering GO:0043113 3 0.228
mesenchymal cell differentiation GO:0048762 1 0.227
glial cell development GO:0021782 27 0.227
lateral inhibition GO:0046331 206 0.225
glycosyl compound metabolic process GO:1901657 127 0.215
hippo signaling GO:0035329 20 0.215
branching involved in open tracheal system development GO:0060446 45 0.215
synaptic growth at neuromuscular junction GO:0051124 119 0.213
positive regulation of cell proliferation GO:0008284 47 0.204
negative regulation of heart induction by canonical wnt signaling pathway GO:0003136 3 0.204
enteroendocrine cell differentiation GO:0035883 1 0.201
maintenance of cell polarity GO:0030011 18 0.200
carbohydrate derivative biosynthetic process GO:1901137 85 0.200
meiosis i GO:0007127 59 0.196
multi organism behavior GO:0051705 175 0.196
negative regulation of cellular metabolic process GO:0031324 382 0.195
establishment of protein localization to membrane GO:0090150 11 0.195
post golgi vesicle mediated transport GO:0006892 11 0.191
vesicle mediated transport GO:0016192 381 0.188
regulation of cell cycle g1 s phase transition GO:1902806 23 0.186
neuron recognition GO:0008038 101 0.182
glial cell differentiation GO:0010001 35 0.181
gland development GO:0048732 191 0.181
regulation of cellular component size GO:0032535 98 0.174
establishment or maintenance of polarity of follicular epithelium GO:0016334 26 0.174
organ growth GO:0035265 56 0.173
cell motility GO:0048870 251 0.171
cellular component assembly involved in morphogenesis GO:0010927 151 0.170
establishment of cell polarity GO:0030010 40 0.170
carbohydrate derivative metabolic process GO:1901135 217 0.170
gtp metabolic process GO:0046039 72 0.170
muscle tissue development GO:0060537 30 0.168
positive regulation of stem cell differentiation GO:2000738 3 0.165
embryonic hemopoiesis GO:0035162 26 0.165
g protein coupled receptor signaling pathway GO:0007186 136 0.163
positive regulation of establishment of protein localization to plasma membrane GO:0090004 3 0.162
regulation of cell substrate adhesion GO:0010810 2 0.160
dorsal closure amnioserosa morphology change GO:0046664 7 0.157
regulation of actin filament bundle assembly GO:0032231 8 0.156
single organism catabolic process GO:0044712 228 0.155
morphogenesis of follicular epithelium GO:0016333 36 0.154
gastrulation GO:0007369 70 0.152
polarized epithelial cell differentiation GO:0030859 10 0.151
morphogenesis of larval imaginal disc epithelium GO:0016335 5 0.147
regulation of axonogenesis GO:0050770 32 0.146
skeletal muscle fiber development GO:0048741 3 0.146
regulation of heart morphogenesis GO:2000826 3 0.146
substrate dependent cell migration cell extension GO:0006930 3 0.145
notch signaling pathway GO:0007219 120 0.144
dephosphorylation GO:0016311 51 0.142
single organism nuclear import GO:1902593 51 0.141
malpighian tubule morphogenesis GO:0007443 44 0.140
determination of bilateral symmetry GO:0009855 13 0.139
embryonic digestive tract development GO:0048566 5 0.139
telencephalon development GO:0021537 2 0.139
establishment of monopolar cell polarity GO:0061162 15 0.139
homeostatic process GO:0042592 199 0.139
initiation of dorsal closure GO:0007392 12 0.138
eye photoreceptor cell fate commitment GO:0042706 37 0.138
larval development GO:0002164 104 0.135
apoptotic process involved in morphogenesis GO:0060561 3 0.134
protein localization to membrane GO:0072657 19 0.134
mating GO:0007618 120 0.132
intracellular protein transport GO:0006886 104 0.132
morphogenesis of a branching epithelium GO:0061138 45 0.132
purine nucleoside triphosphate catabolic process GO:0009146 108 0.130
immune system process GO:0002376 347 0.129
embryonic digestive tract morphogenesis GO:0048557 4 0.128
renal system development GO:0072001 72 0.126
negative regulation of rna biosynthetic process GO:1902679 240 0.124
unidimensional cell growth GO:0009826 15 0.122
embryonic foregut morphogenesis GO:0048617 3 0.121
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.121
single organismal cell cell adhesion GO:0016337 45 0.119
protein transport GO:0015031 155 0.117
organonitrogen compound metabolic process GO:1901564 318 0.117
establishment of organelle localization GO:0051656 122 0.117
developmental growth GO:0048589 280 0.116
regulation of organ growth GO:0046620 42 0.115
regulation of developmental growth GO:0048638 174 0.114
organic substance transport GO:0071702 257 0.114
kidney epithelium development GO:0072073 3 0.113
regulation of cell proliferation GO:0042127 163 0.112
purine ribonucleoside metabolic process GO:0046128 127 0.112
actin cytoskeleton organization GO:0030036 206 0.112
extracellular matrix organization GO:0030198 32 0.111
retina development in camera type eye GO:0060041 4 0.111
negative regulation of apoptotic process GO:0043066 63 0.111
regulation of cellular localization GO:0060341 136 0.111
oocyte axis specification GO:0007309 108 0.111
tracheal outgrowth open tracheal system GO:0007426 18 0.109
regulation of tube diameter GO:0035296 14 0.109
regulation of intracellular transport GO:0032386 64 0.108
pericardium development GO:0060039 2 0.108
non sensory hair organization GO:0035316 47 0.107
spermatid differentiation GO:0048515 114 0.106
anterior midgut ectodermal morphogenesis GO:0007441 4 0.106
stem cell development GO:0048864 79 0.105
establishment of imaginal disc derived wing hair orientation GO:0001737 24 0.105
gastrulation with mouth forming first GO:0001703 36 0.104
circulatory system development GO:0072359 82 0.104
melanotic encapsulation of foreign target GO:0035011 30 0.104
branching morphogenesis of an epithelial tube GO:0048754 45 0.103
regulation of phosphorylation GO:0042325 147 0.102
cell surface receptor signaling pathway involved in heart development GO:0061311 3 0.102
nuclear division GO:0000280 332 0.101
oocyte microtubule cytoskeleton organization GO:0016325 35 0.101
skin development GO:0043588 65 0.101
imaginal disc eversion GO:0007561 4 0.101
cellular macromolecule localization GO:0070727 220 0.100
trachea development GO:0060438 29 0.100
foregut morphogenesis GO:0007440 10 0.100
regulation of notch signaling pathway GO:0008593 100 0.099
negative regulation of organ growth GO:0046621 15 0.099
regulation of epithelial cell proliferation GO:0050678 4 0.099
regulation of cell adhesion GO:0030155 27 0.099
establishment of mitotic spindle orientation GO:0000132 13 0.098
heart morphogenesis GO:0003007 32 0.098
establishment of protein localization to organelle GO:0072594 62 0.097
hemopoiesis GO:0030097 46 0.096
cell fate determination GO:0001709 91 0.096
muscle attachment GO:0016203 36 0.096
cuticle development GO:0042335 86 0.095
actin filament bundle organization GO:0061572 28 0.094
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.094
cellular protein modification process GO:0006464 438 0.094
programmed cell death GO:0012501 257 0.094
maternal determination of anterior posterior axis embryo GO:0008358 74 0.092
skeletal muscle organ development GO:0060538 48 0.091
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.090
germ line stem cell maintenance GO:0030718 50 0.090
cell elongation involved in imaginal disc derived wing morphogenesis GO:0090254 5 0.089
immune response GO:0006955 246 0.089
cellular response to dna damage stimulus GO:0006974 223 0.088
second mitotic wave involved in compound eye morphogenesis GO:0016330 7 0.088
compound eye photoreceptor fate commitment GO:0001752 36 0.088
axonal fasciculation GO:0007413 12 0.087
substrate dependent cell migration GO:0006929 3 0.087
columnar cuboidal epithelial cell development GO:0002066 249 0.087
germ line cyst formation GO:0048134 44 0.085
regulation of tube size GO:0035150 46 0.084
rhythmic behavior GO:0007622 76 0.084
positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743 5 0.084
actin polymerization or depolymerization GO:0008154 31 0.084
cytoskeleton dependent cytokinesis GO:0061640 81 0.083
regulation of photoreceptor cell differentiation GO:0046532 34 0.083
regulation of neurogenesis GO:0050767 158 0.082
regulation of actin polymerization or depolymerization GO:0008064 27 0.082
positive regulation of developmental process GO:0051094 143 0.079
ovarian follicle cell development GO:0030707 248 0.079
regulation of organelle organization GO:0033043 196 0.079
single organism biosynthetic process GO:0044711 206 0.079
detection of stimulus GO:0051606 156 0.079
cell migration involved in gastrulation GO:0042074 9 0.078
positive regulation of filopodium assembly GO:0051491 15 0.077
cell proliferation GO:0008283 299 0.077
negative regulation of developmental process GO:0051093 201 0.076
dorsal ventral axis specification GO:0009950 66 0.076
regulation of intracellular protein transport GO:0033157 46 0.076
positive regulation of rho gtpase activity GO:0032321 19 0.076
brain development GO:0007420 120 0.075
imaginal disc derived wing hair organization GO:0035317 45 0.075
neuron fate commitment GO:0048663 50 0.075
positive regulation of nucleic acid templated transcription GO:1903508 266 0.075
dorsal trunk growth open tracheal system GO:0035001 7 0.075
mesoderm development GO:0007498 78 0.074
cellular amine metabolic process GO:0044106 12 0.074
hindgut morphogenesis GO:0007442 58 0.074
nephron development GO:0072006 3 0.074
mesodermal cell differentiation GO:0048333 7 0.074
nucleotide catabolic process GO:0009166 109 0.073
mesenchymal cell development GO:0014031 1 0.073
hindbrain development GO:0030902 2 0.073
synapse assembly GO:0007416 143 0.073
transmission of nerve impulse GO:0019226 12 0.072
phosphorylation GO:0016310 294 0.072
female germ line cyst formation GO:0048135 42 0.072
regulation of small gtpase mediated signal transduction GO:0051056 93 0.071
spermatid development GO:0007286 98 0.070
negative regulation of neuron apoptotic process GO:0043524 14 0.070
maintenance of apical basal cell polarity GO:0035090 8 0.069
developmental maturation GO:0021700 172 0.069
purine nucleoside metabolic process GO:0042278 127 0.069
glial cell migration GO:0008347 31 0.069
genitalia development GO:0048806 26 0.068
maintenance of location in cell GO:0051651 28 0.068
ribonucleoside catabolic process GO:0042454 112 0.068
head involution GO:0008258 35 0.068
purine ribonucleotide catabolic process GO:0009154 109 0.067
regulation of neuron differentiation GO:0045664 103 0.067
torc1 signaling GO:0038202 12 0.067
protein localization GO:0008104 284 0.067
inter male aggressive behavior GO:0002121 60 0.066
organic acid metabolic process GO:0006082 103 0.066
intraspecies interaction between organisms GO:0051703 4 0.066
regulation of establishment of protein localization to plasma membrane GO:0090003 7 0.065
regulation of immune system process GO:0002682 176 0.064
positive regulation of epithelial cell differentiation GO:0030858 1 0.064
response to radiation GO:0009314 155 0.064
response to starvation GO:0042594 97 0.064
myotube cell development GO:0014904 3 0.063
stem cell differentiation GO:0048863 117 0.063
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.063
cuticle pattern formation GO:0035017 27 0.062
regulation of heart induction GO:0090381 3 0.062
organophosphate metabolic process GO:0019637 195 0.062
lipid storage GO:0019915 38 0.062
negative regulation of epithelial cell proliferation GO:0050680 4 0.062
regulation of compound eye photoreceptor development GO:0045314 12 0.062
multicellular organismal homeostasis GO:0048871 41 0.061
endomembrane system organization GO:0010256 119 0.060
dendrite morphogenesis GO:0048813 199 0.060
meiotic cell cycle process GO:1903046 132 0.060
small molecule metabolic process GO:0044281 305 0.060
developmental cell growth GO:0048588 52 0.060
cell competition in a multicellular organism GO:0035212 10 0.059
nucleotide metabolic process GO:0009117 161 0.059
wnt signaling pathway involved in heart development GO:0003306 3 0.059
striated muscle tissue development GO:0014706 27 0.059
protein import into nucleus GO:0006606 51 0.058
regulation of actin filament based process GO:0032970 42 0.058
mesoderm formation GO:0001707 21 0.058
response to lipopolysaccharide GO:0032496 4 0.058
negative regulation of neurogenesis GO:0050768 53 0.058
regulation of cellular ketone metabolic process GO:0010565 3 0.058
regulation of eye photoreceptor cell development GO:0042478 13 0.058
positive regulation of nucleotide catabolic process GO:0030813 46 0.058
protein localization to nucleus GO:0034504 55 0.058
apical protein localization GO:0045176 5 0.057
regulation of sequestering of calcium ion GO:0051282 3 0.056
negative regulation of nucleic acid templated transcription GO:1903507 240 0.056
organelle fission GO:0048285 340 0.056
single organism intracellular transport GO:1902582 207 0.055
regulation of neuron apoptotic process GO:0043523 16 0.055
peripheral nervous system development GO:0007422 52 0.055
lipid metabolic process GO:0006629 121 0.055
regulation of phosphate metabolic process GO:0019220 210 0.055
hematopoietic or lymphoid organ development GO:0048534 57 0.054
germ band extension GO:0007377 11 0.054
exocrine system development GO:0035272 162 0.054
cell death GO:0008219 279 0.054
cell maturation GO:0048469 144 0.054
regulation of cell cycle GO:0051726 291 0.054
establishment of epithelial cell polarity GO:0090162 13 0.054
anterior posterior pattern specification GO:0009952 136 0.053
reproductive behavior GO:0019098 122 0.053
negative regulation of cell fate specification GO:0009996 15 0.053
positive regulation of protein binding GO:0032092 1 0.053
germ cell migration GO:0008354 43 0.053
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.052
cell growth GO:0016049 108 0.051
heterotypic cell cell adhesion GO:0034113 1 0.051
regulation of catabolic process GO:0009894 170 0.051
positive regulation of cell size GO:0045793 21 0.051
regulation of actin cytoskeleton organization GO:0032956 42 0.051
regulation of molecular function GO:0065009 217 0.050
determination of digestive tract left right asymmetry GO:0071907 6 0.049
negative regulation of nervous system development GO:0051961 92 0.049
establishment of spindle localization GO:0051293 22 0.049
negative regulation of cell development GO:0010721 62 0.049
imaginal disc derived leg morphogenesis GO:0007480 80 0.049
establishment of spindle orientation GO:0051294 18 0.049
negative regulation of rna metabolic process GO:0051253 251 0.049
cytoplasm organization GO:0007028 64 0.049
r8 cell fate specification GO:0045464 5 0.048
striated muscle cell differentiation GO:0051146 90 0.048
regulation of programmed cell death GO:0043067 152 0.048
regulation of dendrite morphogenesis GO:0048814 28 0.048
ameboidal type cell migration GO:0001667 151 0.048
ribonucleoside metabolic process GO:0009119 127 0.047
neuronal action potential GO:0019228 10 0.047
gtp catabolic process GO:0006184 72 0.047
chitin based embryonic cuticle biosynthetic process GO:0008362 16 0.047
establishment of protein localization GO:0045184 163 0.046
epithelial tube morphogenesis GO:0060562 88 0.046
cellular response to extracellular stimulus GO:0031668 64 0.046
regulation of dendrite development GO:0050773 37 0.046
positive regulation of intracellular protein transport GO:0090316 30 0.046
learning or memory GO:0007611 141 0.045
non canonical wnt signaling pathway GO:0035567 8 0.045
purine ribonucleoside catabolic process GO:0046130 112 0.044
apoptotic process GO:0006915 159 0.044
regulation of stem cell differentiation GO:2000736 14 0.044
nucleoside catabolic process GO:0009164 112 0.044
regulation of cytoskeleton organization GO:0051493 89 0.044
hindgut development GO:0061525 58 0.044
axon ensheathment GO:0008366 10 0.044
regulation of localization GO:0032879 275 0.043
male meiosis GO:0007140 52 0.043
ras protein signal transduction GO:0007265 88 0.043
autophagy GO:0006914 108 0.043
epidermal cell differentiation GO:0009913 51 0.043
ion transport GO:0006811 145 0.043
purine containing compound metabolic process GO:0072521 155 0.043
positive regulation of transcription dna templated GO:0045893 266 0.042
negative regulation of response to stimulus GO:0048585 258 0.042
lipid modification GO:0030258 24 0.042
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.042
positive regulation of gtpase activity GO:0043547 43 0.042
positive regulation of pathway restricted smad protein phosphorylation GO:0010862 1 0.042
antimicrobial humoral response GO:0019730 99 0.041
regulation of intracellular signal transduction GO:1902531 236 0.041

crb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
auditory system disease DOID:2742 0 0.065
nonsyndromic deafness DOID:0050563 0 0.065
sensory system disease DOID:0050155 0 0.065
disease of anatomical entity DOID:7 0 0.065
nervous system disease DOID:863 0 0.065
autosomal dominant nonsyndromic deafness DOID:0050564 0 0.064
congenital heart disease DOID:1682 0 0.048
tetralogy of fallot DOID:6419 0 0.048
heart disease DOID:114 0 0.048
cardiovascular system disease DOID:1287 0 0.048