Drosophila melanogaster

40 known processes

Csp (Dmel_CG6395)

Cysteine string protein

(Aliases: Cys,l(3)03988,Dmel\CG6395,CSP32,D-CSP,DCSP-1,csp,anon-WO02059370.50,Dcsp,csp32,CG6395,ab49,MAB ab49,csp29,D.M.CSP,CSP)

Csp biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
synaptic transmission GO:0007268 288 0.998
neuromuscular junction development GO:0007528 149 0.998
neuromuscular synaptic transmission GO:0007274 67 0.983
synapse organization GO:0050808 196 0.976
regulation of developmental growth GO:0048638 174 0.876
establishment of synaptic vesicle localization GO:0097480 50 0.868
synaptic vesicle transport GO:0048489 50 0.820
synaptic vesicle endocytosis GO:0048488 28 0.760
cell motility GO:0048870 251 0.712
synaptic vesicle localization GO:0097479 53 0.702
multi multicellular organism process GO:0044706 123 0.692
positive regulation of gene expression GO:0010628 290 0.684
embryonic morphogenesis GO:0048598 206 0.676
establishment of organelle localization GO:0051656 122 0.662
growth GO:0040007 359 0.644
apoptotic process GO:0006915 159 0.618
Mouse
developmental maturation GO:0021700 172 0.592
negative regulation of cell communication GO:0010648 223 0.577
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.552
regulation of synapse structure and activity GO:0050803 128 0.518
vesicle mediated transport GO:0016192 381 0.513
cell division GO:0051301 248 0.508
negative regulation of cellular metabolic process GO:0031324 382 0.487
synapse assembly GO:0007416 143 0.485
vesicle localization GO:0051648 55 0.475
cell migration GO:0016477 238 0.442
establishment of localization in cell GO:0051649 402 0.431
regulation of phosphorus metabolic process GO:0051174 210 0.430
taxis GO:0042330 304 0.417
cell junction organization GO:0034330 57 0.407
localization of cell GO:0051674 257 0.373
regulation of synaptic transmission GO:0050804 69 0.359
regulation of growth GO:0040008 233 0.353
protein localization GO:0008104 284 0.352
regulation of anatomical structure morphogenesis GO:0022603 242 0.341
negative regulation of cell cycle GO:0045786 116 0.339
axon guidance GO:0007411 233 0.334
neurotransmitter secretion GO:0007269 35 0.331
regulation of cell cycle process GO:0010564 181 0.313
response to temperature stimulus GO:0009266 106 0.305
epithelial cell proliferation GO:0050673 15 0.304
intracellular transport GO:0046907 228 0.300
positive regulation of macromolecule metabolic process GO:0010604 405 0.293
synaptic growth at neuromuscular junction GO:0051124 119 0.291
eye development GO:0001654 323 0.287
organelle localization GO:0051640 148 0.285
synaptic vesicle recycling GO:0036465 28 0.272
spermatogenesis GO:0007283 200 0.269
regulation of localization GO:0032879 275 0.266
cellular response to nutrient levels GO:0031669 62 0.266
oocyte axis specification GO:0007309 108 0.265
regulation of mitotic cell cycle GO:0007346 190 0.261
phosphorylation GO:0016310 294 0.260
negative regulation of biosynthetic process GO:0009890 277 0.253
positive regulation of signaling GO:0023056 243 0.251
positive regulation of cellular biosynthetic process GO:0031328 316 0.248
neurotransmitter transport GO:0006836 37 0.247
negative regulation of signaling GO:0023057 219 0.245
response to abiotic stimulus GO:0009628 341 0.244
regulation of cellular component biogenesis GO:0044087 201 0.243
chemotaxis GO:0006935 249 0.240
organic substance transport GO:0071702 257 0.239
regulation of programmed cell death GO:0043067 152 0.237
Mouse
establishment of vesicle localization GO:0051650 51 0.218
single organism behavior GO:0044708 391 0.213
regulation of protein metabolic process GO:0051246 256 0.208
regulation of cell cycle GO:0051726 291 0.204
sensory organ morphogenesis GO:0090596 260 0.196
establishment of protein localization GO:0045184 163 0.196
central nervous system development GO:0007417 201 0.196
synaptic vesicle fusion to presynaptic membrane GO:0031629 7 0.192
locomotory behavior GO:0007626 176 0.189
positive regulation of nucleic acid templated transcription GO:1903508 266 0.182
response to transforming growth factor beta GO:0071559 18 0.182
oocyte construction GO:0007308 112 0.180
positive regulation of apoptotic signaling pathway GO:2001235 4 0.180
regulation of reproductive process GO:2000241 54 0.170
protein modification process GO:0036211 438 0.170
positive regulation of transcription dna templated GO:0045893 266 0.169
developmental growth GO:0048589 280 0.168
oocyte differentiation GO:0009994 145 0.166
enzyme linked receptor protein signaling pathway GO:0007167 179 0.163
regulation of multi organism process GO:0043900 131 0.162
positive regulation of cell communication GO:0010647 250 0.161
ion transmembrane transport GO:0034220 122 0.159
synaptic vesicle exocytosis GO:0016079 16 0.155
regulation of organelle organization GO:0033043 196 0.153
determination of adult lifespan GO:0008340 137 0.150
intracellular protein transport GO:0006886 104 0.142
regulation of transport GO:0051049 181 0.141
positive regulation of neurotransmitter secretion GO:0001956 2 0.137
protein catabolic process GO:0030163 101 0.135
cellular macromolecular complex assembly GO:0034622 153 0.134
cellular protein localization GO:0034613 160 0.133
positive regulation of rna metabolic process GO:0051254 271 0.132
single organism cellular localization GO:1902580 180 0.132
negative regulation of mitotic cell cycle GO:0045930 109 0.131
negative regulation of multicellular organismal process GO:0051241 142 0.129
positive regulation of protein modification process GO:0031401 58 0.127
negative regulation of signal transduction GO:0009968 206 0.122
cell maturation GO:0048469 144 0.121
modification dependent protein catabolic process GO:0019941 78 0.116
regulation of protein modification process GO:0031399 112 0.115
protein transport GO:0015031 155 0.114
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.113
pigmentation GO:0043473 75 0.113
protein complex assembly GO:0006461 200 0.113
autophagy GO:0006914 108 0.113
cell proliferation GO:0008283 299 0.112
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.110
regionalization GO:0003002 416 0.109
regulation of pole plasm oskar mrna localization GO:0007317 27 0.104
protein import into nucleus GO:0006606 51 0.102
cellular macromolecule localization GO:0070727 220 0.100
regulation of cellular localization GO:0060341 136 0.100
cell junction assembly GO:0034329 42 0.097
intracellular mrna localization GO:0008298 66 0.096
positive regulation of signal transduction GO:0009967 223 0.093
regulation of protein transport GO:0051223 57 0.090
sensory perception of mechanical stimulus GO:0050954 72 0.090
positive regulation of cellular component organization GO:0051130 156 0.089
cell death GO:0008219 279 0.089
Mouse
negative regulation of phosphorus metabolic process GO:0010563 45 0.089
axon development GO:0061564 297 0.085
organelle fusion GO:0048284 46 0.084
segmentation GO:0035282 207 0.081
adherens junction organization GO:0034332 27 0.081
regulation of cellular response to stress GO:0080135 89 0.080
positive regulation of biosynthetic process GO:0009891 316 0.078
g protein coupled receptor signaling pathway GO:0007186 136 0.077
macromolecular complex assembly GO:0065003 256 0.077
regulation of neurotransmitter secretion GO:0046928 14 0.075
organelle assembly GO:0070925 198 0.075
regulation of short term neuronal synaptic plasticity GO:0048172 5 0.074
ubiquitin dependent protein catabolic process GO:0006511 78 0.073
tissue morphogenesis GO:0048729 297 0.070
male gamete generation GO:0048232 201 0.070
regulation of multicellular organismal development GO:2000026 414 0.069
negative regulation of phosphorylation GO:0042326 35 0.068
establishment of protein localization to plasma membrane GO:0090002 9 0.068
eye morphogenesis GO:0048592 260 0.066
regulation of intracellular protein transport GO:0033157 46 0.065
negative regulation of cell cycle process GO:0010948 109 0.065
negative regulation of developmental process GO:0051093 201 0.064
membrane fusion GO:0061025 42 0.064
reproductive structure development GO:0048608 74 0.064
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.063
organelle fission GO:0048285 340 0.063
notch signaling pathway GO:0007219 120 0.063
rna localization GO:0006403 115 0.062
regulation of cell differentiation GO:0045595 302 0.062
response to biotic stimulus GO:0009607 294 0.062
mitotic nuclear division GO:0007067 213 0.061
gliogenesis GO:0042063 80 0.061
maternal determination of anterior posterior axis embryo GO:0008358 74 0.061
positive regulation of apoptotic process GO:0043065 47 0.061
single organism membrane fusion GO:0044801 42 0.061
aging GO:0007568 143 0.059
synaptic vesicle priming GO:0016082 1 0.058
positive regulation of response to stimulus GO:0048584 323 0.057
positive regulation of phosphorylation GO:0042327 87 0.057
regulation of cell development GO:0060284 215 0.053
peripheral nervous system development GO:0007422 52 0.053
regulation of epithelial cell proliferation GO:0050678 4 0.053
negative regulation of programmed cell death GO:0043069 72 0.053
Mouse
positive regulation of organelle organization GO:0010638 65 0.052
endocytosis GO:0006897 310 0.052
actin filament based process GO:0030029 220 0.051
negative regulation of response to stimulus GO:0048585 258 0.051
regulation of cellular protein metabolic process GO:0032268 243 0.051
regulation of autophagy GO:0010506 62 0.051
protein import GO:0017038 55 0.050
nucleocytoplasmic transport GO:0006913 72 0.050
nuclear transport GO:0051169 72 0.050
mating behavior GO:0007617 106 0.049
autophagic vacuole assembly GO:0000045 2 0.049
digestive tract development GO:0048565 149 0.048
protein phosphorylation GO:0006468 169 0.048
jnk cascade GO:0007254 50 0.048
actin cytoskeleton organization GO:0030036 206 0.047
epithelial cell differentiation GO:0030855 322 0.046
neuron projection guidance GO:0097485 241 0.046
cardiovascular system development GO:0072358 82 0.046
negative regulation of gene expression GO:0010629 387 0.045
regulation of protein import into nucleus GO:0042306 28 0.044
terminal button organization GO:0072553 19 0.043
morphogenesis of an epithelium GO:0002009 276 0.043
oxoacid metabolic process GO:0043436 103 0.043
oocyte development GO:0048599 124 0.042
negative regulation of nucleic acid templated transcription GO:1903507 240 0.042
positive regulation of developmental process GO:0051094 143 0.041
regulation of mapk cascade GO:0043408 92 0.041
programmed cell death GO:0012501 257 0.041
Mouse
negative regulation of cellular biosynthetic process GO:0031327 277 0.040
regulation of cell maturation GO:1903429 27 0.040
lipid metabolic process GO:0006629 121 0.039
embryo development ending in birth or egg hatching GO:0009792 152 0.039
regulation of nervous system development GO:0051960 248 0.039
regulation of establishment of protein localization GO:0070201 61 0.038
membrane tubulation GO:0097320 4 0.038
carboxylic acid metabolic process GO:0019752 92 0.038
single organism membrane organization GO:0044802 93 0.038
regulation of synapse assembly GO:0051963 94 0.038
death GO:0016265 284 0.037
Mouse
cell adhesion GO:0007155 136 0.037
regulation of phosphorylation GO:0042325 147 0.037
regulation of response to external stimulus GO:0032101 115 0.037
modification dependent macromolecule catabolic process GO:0043632 79 0.037
regulation of intracellular signal transduction GO:1902531 236 0.037
larval development GO:0002164 104 0.036
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.035
regulation of protein localization GO:0032880 76 0.035
adult locomotory behavior GO:0008344 76 0.035
transmembrane transport GO:0055085 139 0.035
regulation of cell death GO:0010941 173 0.035
Mouse
positive regulation of catabolic process GO:0009896 105 0.035
catabolic process GO:0009056 409 0.035
cell cycle arrest GO:0007050 4 0.034
phagocytosis GO:0006909 215 0.034
multicellular organismal reproductive behavior GO:0033057 110 0.034
mating GO:0007618 120 0.034
regulation of hemocyte proliferation GO:0035206 37 0.033
negative regulation of synaptic growth at neuromuscular junction GO:0045886 39 0.033
protein localization to nucleus GO:0034504 55 0.033
response to starvation GO:0042594 97 0.033
cellular protein modification process GO:0006464 438 0.033
cytoplasmic transport GO:0016482 130 0.033
regulation of neuron death GO:1901214 26 0.033
Mouse
regulation of phosphatase activity GO:0010921 3 0.033
negative regulation of apoptotic process GO:0043066 63 0.033
Mouse
regulation of catabolic process GO:0009894 170 0.032
single organism nuclear import GO:1902593 51 0.032
mapk cascade GO:0000165 107 0.032
regulation of neuronal synaptic plasticity GO:0048168 8 0.032
protein targeting to nucleus GO:0044744 51 0.031
regulation of neurotransmitter levels GO:0001505 38 0.031
regulation of cell cycle phase transition GO:1901987 130 0.030
protein targeting GO:0006605 64 0.030
single organism intracellular transport GO:1902582 207 0.030
embryonic pattern specification GO:0009880 174 0.030
positive regulation of protein complex assembly GO:0031334 22 0.029
ameboidal type cell migration GO:0001667 151 0.029
development of primary sexual characteristics GO:0045137 50 0.029
mitotic g2 dna damage checkpoint GO:0007095 69 0.028
positive regulation of programmed cell death GO:0043068 62 0.028
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.028
regulation of stress activated mapk cascade GO:0032872 41 0.027
histone modification GO:0016570 106 0.027
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.027
positive regulation of cellular protein metabolic process GO:0032270 118 0.027
skeletal muscle organ development GO:0060538 48 0.027
cellular protein catabolic process GO:0044257 83 0.027
cellular component assembly involved in morphogenesis GO:0010927 151 0.027
regulation of steroid metabolic process GO:0019218 2 0.027
lipid biosynthetic process GO:0008610 46 0.027
regulation of multicellular organism growth GO:0040014 40 0.026
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.026
negative regulation of rna biosynthetic process GO:1902679 240 0.026
positive regulation of cell migration GO:0030335 2 0.026
spindle organization GO:0007051 253 0.026
negative regulation of transcription dna templated GO:0045892 237 0.025
pole plasm mrna localization GO:0019094 49 0.025
cellular macromolecule catabolic process GO:0044265 136 0.025
muscle structure development GO:0061061 224 0.025
negative regulation of cellular component organization GO:0051129 108 0.025
digestive tract morphogenesis GO:0048546 127 0.025
regulation of synapse organization GO:0050807 110 0.025
nuclear import GO:0051170 51 0.025
sensory perception GO:0007600 196 0.025
tripartite regional subdivision GO:0007351 103 0.025
negative regulation of cell cycle phase transition GO:1901988 103 0.025
transcription from rna polymerase ii promoter GO:0006366 368 0.024
multicellular organismal aging GO:0010259 140 0.024
establishment of protein localization to organelle GO:0072594 62 0.024
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.024
regulation of response to stress GO:0080134 200 0.023
positive regulation of intracellular signal transduction GO:1902533 116 0.023
purine nucleoside monophosphate metabolic process GO:0009126 50 0.023
centriole replication GO:0007099 24 0.023
cognition GO:0050890 141 0.023
digestive system development GO:0055123 149 0.023
negative regulation of molecular function GO:0044092 51 0.023
regulation of protein localization to nucleus GO:1900180 29 0.023
cellular amino acid metabolic process GO:0006520 61 0.023
cellular response to transforming growth factor beta stimulus GO:0071560 18 0.022
spinal cord development GO:0021510 1 0.022
anterior posterior axis specification embryo GO:0008595 103 0.022
cell cell junction organization GO:0045216 55 0.021
regulation of nuclear division GO:0051783 58 0.021
apoptotic signaling pathway GO:0097190 27 0.021
regulation of protein kinase activity GO:0045859 51 0.021
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.021
regulation of phosphate metabolic process GO:0019220 210 0.021
positive regulation of protein metabolic process GO:0051247 128 0.021
regulation of protein catabolic process GO:0042176 55 0.021
positive regulation of rna biosynthetic process GO:1902680 266 0.021
regulation of secretion GO:0051046 44 0.020
muscle contraction GO:0006936 13 0.020
cellular protein complex assembly GO:0043623 71 0.020
regulation of molecular function GO:0065009 217 0.020
regulation of cell division GO:0051302 72 0.020
negative regulation of response to oxidative stress GO:1902883 1 0.019
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 14 0.019
cytokinesis GO:0000910 90 0.019
pigment cell differentiation GO:0050931 3 0.019
oocyte anterior posterior axis specification GO:0007314 72 0.019
tube development GO:0035295 244 0.019
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.019
negative regulation of cell death GO:0060548 81 0.018
Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.018
regulation of synaptic plasticity GO:0048167 14 0.018
male mating behavior GO:0060179 70 0.018
regulation of endocytosis GO:0030100 37 0.018
cell rearrangement involved in malpighian tubule morphogenesis GO:0061334 3 0.018
secretion by cell GO:0032940 101 0.018
muscle organ development GO:0007517 127 0.018
regulation of meiosis GO:0040020 3 0.018
negative regulation of protein metabolic process GO:0051248 85 0.018
sex differentiation GO:0007548 81 0.018
negative regulation of phosphate metabolic process GO:0045936 45 0.018
positive regulation of neurotransmitter transport GO:0051590 2 0.018
posttranscriptional regulation of gene expression GO:0010608 145 0.017
establishment of cell polarity GO:0030010 40 0.017
vesicle organization GO:0016050 44 0.017
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.017
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 6 0.017
regulation of membrane potential GO:0042391 35 0.017
cytoskeleton dependent cytokinesis GO:0061640 81 0.017
small molecule metabolic process GO:0044281 305 0.017
positive regulation of behavior GO:0048520 19 0.017
organophosphate metabolic process GO:0019637 195 0.017
receptor recycling GO:0001881 2 0.017
cellular response to growth factor stimulus GO:0071363 30 0.016
protein kinase b signaling GO:0043491 1 0.016
negative regulation of epithelial cell proliferation GO:0050680 4 0.016
regulation of circadian rhythm GO:0042752 49 0.016
organ growth GO:0035265 56 0.016
regulation of cellular ketone metabolic process GO:0010565 3 0.016
regulation of protein targeting GO:1903533 29 0.016
cell type specific apoptotic process GO:0097285 38 0.016
Mouse
regulation of notch signaling pathway GO:0008593 100 0.016
mesenchymal cell differentiation GO:0048762 1 0.016
phospholipid metabolic process GO:0006644 23 0.016
inorganic cation transmembrane transport GO:0098662 61 0.016
reproductive system development GO:0061458 74 0.015
heart morphogenesis GO:0003007 32 0.015
eggshell formation GO:0030703 105 0.015
proteasomal protein catabolic process GO:0010498 59 0.015
response to nutrient levels GO:0031667 114 0.015
signal release GO:0023061 49 0.015
forebrain development GO:0030900 2 0.015
nucleoside phosphate biosynthetic process GO:1901293 34 0.015
intrinsic apoptotic signaling pathway GO:0097193 16 0.015
membrane organization GO:0061024 112 0.015
organic substance catabolic process GO:1901575 308 0.015
regulation of response to oxidative stress GO:1902882 4 0.015
brain development GO:0007420 120 0.014
regulation of oocyte development GO:0060281 27 0.014
positive regulation of multicellular organismal process GO:0051240 143 0.014
negative regulation of cellular protein metabolic process GO:0032269 85 0.014
neuron death GO:0070997 27 0.014
Mouse
stem cell proliferation GO:0072089 88 0.014
synaptic transmission dopaminergic GO:0001963 2 0.014
positive regulation of protein localization to plasma membrane GO:1903078 3 0.014
cellular amine metabolic process GO:0044106 12 0.014
positive regulation of growth GO:0045927 75 0.014
muscle system process GO:0003012 21 0.014
negative regulation of developmental growth GO:0048640 64 0.014
negative regulation of nervous system development GO:0051961 92 0.014
blastoderm segmentation GO:0007350 159 0.014
mitotic spindle organization GO:0007052 220 0.014
response to organic substance GO:0010033 284 0.014
single organism biosynthetic process GO:0044711 206 0.013
anterior posterior pattern specification GO:0009952 136 0.013
regulation of embryonic development GO:0045995 68 0.013
endomembrane system organization GO:0010256 119 0.013
negative regulation of cell proliferation GO:0008285 69 0.013
stress activated protein kinase signaling cascade GO:0031098 55 0.013
regulation of nucleocytoplasmic transport GO:0046822 35 0.013
protein localization to organelle GO:0033365 82 0.013
protein autophosphorylation GO:0046777 15 0.013
positive regulation of cell differentiation GO:0045597 64 0.013
regulation of anatomical structure size GO:0090066 163 0.013
circulatory system development GO:0072359 82 0.013
necrotic cell death GO:0070265 1 0.013
cell growth GO:0016049 108 0.013
regulation of microtubule based process GO:0032886 49 0.013
cellular response to chemical stimulus GO:0070887 199 0.013
protein modification by small protein conjugation or removal GO:0070647 106 0.013
signal transduction by phosphorylation GO:0023014 107 0.013
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.012
regulation of secretion by cell GO:1903530 39 0.012
rna processing GO:0006396 147 0.012
mitotic cell cycle checkpoint GO:0007093 88 0.012
positive regulation of response to external stimulus GO:0032103 44 0.012
axonogenesis GO:0007409 290 0.012
positive regulation of cell death GO:0010942 69 0.012
reproductive behavior GO:0019098 122 0.012
chemical homeostasis GO:0048878 92 0.012
epithelial cell development GO:0002064 274 0.012
oviposition GO:0018991 19 0.012
regulation of cellular protein catabolic process GO:1903362 44 0.012
positive regulation of mapk cascade GO:0043410 63 0.011
regulation of ion transport GO:0043269 39 0.011
regulation of protein processing GO:0070613 32 0.011
regulation of protein phosphorylation GO:0001932 64 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.011
embryonic axis specification GO:0000578 107 0.011
aromatic compound catabolic process GO:0019439 166 0.011
regulation of neuron apoptotic process GO:0043523 16 0.011
Mouse
defense response GO:0006952 300 0.011
cellular catabolic process GO:0044248 372 0.011
neuroblast proliferation GO:0007405 74 0.011
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.011
transmission of nerve impulse GO:0019226 12 0.011
social behavior GO:0035176 4 0.010
body morphogenesis GO:0010171 2 0.010
response to radiation GO:0009314 155 0.010
purine ribonucleoside monophosphate catabolic process GO:0009169 38 0.010

Csp disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
motor neuron disease DOID:231 0 0.019
central nervous system disease DOID:331 0 0.019
disease of anatomical entity DOID:7 0 0.019
neurodegenerative disease DOID:1289 0 0.019
nervous system disease DOID:863 0 0.019
musculoskeletal system disease DOID:17 0 0.015