Drosophila melanogaster

51 known processes

Cad74A (Dmel_CG6445)

CG6445 gene product from transcript CG6445-RB

(Aliases: Dmel\CG6445,CT20086,CG6445,cad74A,Cad74B,DCad74B)

Cad74A biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ovarian follicle cell development GO:0030707 248 0.678
epithelial cell differentiation GO:0030855 322 0.354
epithelial cell development GO:0002064 274 0.236
chorion containing eggshell formation GO:0007304 105 0.232
columnar cuboidal epithelial cell development GO:0002066 249 0.167
organonitrogen compound metabolic process GO:1901564 318 0.128
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.111
cellular component assembly involved in morphogenesis GO:0010927 151 0.095
small molecule metabolic process GO:0044281 305 0.082
cilium assembly GO:0042384 38 0.080
compound eye development GO:0048749 307 0.079
Fly
cell projection assembly GO:0030031 94 0.074
dorsal appendage formation GO:0046843 47 0.074
eggshell formation GO:0030703 105 0.074
sensory organ morphogenesis GO:0090596 260 0.073
Fly
tissue morphogenesis GO:0048729 297 0.073
Fly
eye morphogenesis GO:0048592 260 0.073
Fly
regionalization GO:0003002 416 0.069
Fly
carbohydrate derivative metabolic process GO:1901135 217 0.068
establishment or maintenance of cell polarity GO:0007163 167 0.067
Fly
regulation of tube architecture open tracheal system GO:0035152 68 0.063
Fly
intracellular signal transduction GO:0035556 300 0.058
Fly
compound eye morphogenesis GO:0001745 249 0.058
Fly
cell cell signaling involved in cell fate commitment GO:0045168 210 0.056
lateral inhibition GO:0046331 206 0.055
cellular protein modification process GO:0006464 438 0.055
photoreceptor cell differentiation GO:0046530 170 0.053
Fly
protein modification process GO:0036211 438 0.052
cell division GO:0051301 248 0.050
morphogenesis of an epithelium GO:0002009 276 0.050
Fly
nucleoside metabolic process GO:0009116 127 0.046
regulation of cellular component biogenesis GO:0044087 201 0.046
Fly
regulation of growth GO:0040008 233 0.045
response to abiotic stimulus GO:0009628 341 0.045
ameboidal type cell migration GO:0001667 151 0.044
tissue migration GO:0090130 155 0.043
organophosphate metabolic process GO:0019637 195 0.041
ribose phosphate metabolic process GO:0019693 145 0.041
regulation of cell differentiation GO:0045595 302 0.039
Fly
immune system process GO:0002376 347 0.039
cilium organization GO:0044782 41 0.038
appendage development GO:0048736 401 0.038
nucleoside catabolic process GO:0009164 112 0.038
nucleoside triphosphate metabolic process GO:0009141 120 0.038
purine nucleoside catabolic process GO:0006152 112 0.038
cell motility GO:0048870 251 0.037
regulation of cell development GO:0060284 215 0.037
Fly
nucleotide metabolic process GO:0009117 161 0.037
single organism catabolic process GO:0044712 228 0.037
eye photoreceptor cell differentiation GO:0001754 145 0.036
Fly
ovarian follicle cell migration GO:0007297 121 0.035
purine nucleoside triphosphate catabolic process GO:0009146 108 0.035
post embryonic appendage morphogenesis GO:0035120 385 0.035
body morphogenesis GO:0010171 2 0.034
regulation of catalytic activity GO:0050790 185 0.034
phosphorylation GO:0016310 294 0.033
purine nucleoside triphosphate metabolic process GO:0009144 119 0.033
embryonic pattern specification GO:0009880 174 0.033
Fly
establishment of tissue polarity GO:0007164 87 0.032
Fly
regulation of phosphorus metabolic process GO:0051174 210 0.032
eggshell chorion assembly GO:0007306 66 0.032
regulation of immune system process GO:0002682 176 0.032
cellular catabolic process GO:0044248 372 0.032
imaginal disc derived appendage morphogenesis GO:0035114 395 0.032
regulation of multi organism process GO:0043900 131 0.031
positive regulation of cell communication GO:0010647 250 0.031
nucleoside phosphate metabolic process GO:0006753 162 0.031
cell maturation GO:0048469 144 0.031
carboxylic acid metabolic process GO:0019752 92 0.031
regulation of multicellular organismal development GO:2000026 414 0.031
Fly
regulation of notch signaling pathway GO:0008593 100 0.030
Fly
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.030
eye development GO:0001654 323 0.030
Fly
regulation of cellular protein metabolic process GO:0032268 243 0.029
positive regulation of multicellular organismal process GO:0051240 143 0.029
nucleobase containing small molecule metabolic process GO:0055086 174 0.029
positive regulation of signaling GO:0023056 243 0.029
cytoplasmic transport nurse cell to oocyte GO:0007303 12 0.029
endocytosis GO:0006897 310 0.029
response to organic substance GO:0010033 284 0.028
regulation of molecular function GO:0065009 217 0.028
purine ribonucleoside metabolic process GO:0046128 127 0.028
protein phosphorylation GO:0006468 169 0.028
localization of cell GO:0051674 257 0.027
oxoacid metabolic process GO:0043436 103 0.027
purine containing compound metabolic process GO:0072521 155 0.027
establishment of localization in cell GO:0051649 402 0.027
appendage morphogenesis GO:0035107 397 0.027
nucleoside triphosphate catabolic process GO:0009143 108 0.027
purine nucleotide metabolic process GO:0006163 146 0.027
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.027
notch signaling pathway GO:0007219 120 0.027
Fly
positive regulation of catalytic activity GO:0043085 118 0.027
epithelium migration GO:0090132 148 0.027
establishment of planar polarity GO:0001736 87 0.026
Fly
cytoplasmic transport GO:0016482 130 0.026
anterior posterior pattern specification GO:0009952 136 0.026
positive regulation of phosphate metabolic process GO:0045937 139 0.026
positive regulation of response to stimulus GO:0048584 323 0.026
kidney development GO:0001822 3 0.026
glycosyl compound catabolic process GO:1901658 112 0.026
cell proliferation GO:0008283 299 0.026
organelle localization GO:0051640 148 0.026
dna metabolic process GO:0006259 227 0.026
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.026
cellular amino acid metabolic process GO:0006520 61 0.026
positive regulation of developmental process GO:0051094 143 0.025
purine nucleoside metabolic process GO:0042278 127 0.025
negative regulation of response to stimulus GO:0048585 258 0.025
Fly
ribonucleoside triphosphate metabolic process GO:0009199 119 0.025
organic substance catabolic process GO:1901575 308 0.025
ribonucleoside catabolic process GO:0042454 112 0.025
cilium morphogenesis GO:0060271 39 0.025
compound eye photoreceptor cell differentiation GO:0001751 140 0.025
Fly
organic acid metabolic process GO:0006082 103 0.025
regulation of cellular amine metabolic process GO:0033238 3 0.025
forebrain development GO:0030900 2 0.025
imaginal disc derived appendage development GO:0048737 399 0.024
blastoderm segmentation GO:0007350 159 0.024
Fly
biological adhesion GO:0022610 138 0.024
aromatic compound catabolic process GO:0019439 166 0.024
positive regulation of cellular catabolic process GO:0031331 95 0.024
organic cyclic compound catabolic process GO:1901361 168 0.024
cell migration GO:0016477 238 0.024
gland development GO:0048732 191 0.024
axonogenesis GO:0007409 290 0.024
Fly
camera type eye development GO:0043010 4 0.024
regulation of protein modification process GO:0031399 112 0.023
regulation of phosphate metabolic process GO:0019220 210 0.023
cell death GO:0008219 279 0.023
response to bacterium GO:0009617 198 0.023
nephron development GO:0072006 3 0.023
positive regulation of macromolecule metabolic process GO:0010604 405 0.023
single organismal cell cell adhesion GO:0016337 45 0.023
cell adhesion GO:0007155 136 0.023
regulation of neurogenesis GO:0050767 158 0.023
Fly
positive regulation of hydrolase activity GO:0051345 78 0.023
cellular macromolecule localization GO:0070727 220 0.023
purine ribonucleotide metabolic process GO:0009150 145 0.023
growth GO:0040007 359 0.023
programmed cell death GO:0012501 257 0.022
ion transport GO:0006811 145 0.022
epithelial cell migration GO:0010631 148 0.022
actin filament based process GO:0030029 220 0.022
nucleotide catabolic process GO:0009166 109 0.022
actin cytoskeleton organization GO:0030036 206 0.022
ribonucleoside metabolic process GO:0009119 127 0.022
regulation of immune response GO:0050776 118 0.022
catabolic process GO:0009056 409 0.022
wing disc morphogenesis GO:0007472 344 0.022
morphogenesis of a polarized epithelium GO:0001738 93 0.022
Fly
positive regulation of phosphorus metabolic process GO:0010562 139 0.022
neurological system process GO:0050877 358 0.021
kidney epithelium development GO:0072073 3 0.021
embryonic morphogenesis GO:0048598 206 0.021
regulation of intracellular signal transduction GO:1902531 236 0.021
ribonucleotide metabolic process GO:0009259 145 0.021
establishment of organelle localization GO:0051656 122 0.021
positive regulation of molecular function GO:0044093 136 0.021
cellular ketone metabolic process GO:0042180 24 0.021
heterocycle catabolic process GO:0046700 166 0.021
gland morphogenesis GO:0022612 145 0.021
nucleobase containing compound catabolic process GO:0034655 165 0.021
regulation of protein metabolic process GO:0051246 256 0.021
purine ribonucleoside catabolic process GO:0046130 112 0.021
defense response to other organism GO:0098542 225 0.021
negative regulation of cytoskeleton organization GO:0051494 30 0.021
negative regulation of signaling GO:0023057 219 0.020
Fly
positive regulation of compound eye retinal cell programmed cell death GO:0046672 9 0.020
developmental growth GO:0048589 280 0.020
single organism biosynthetic process GO:0044711 206 0.020
wing disc pattern formation GO:0035222 66 0.020
phagocytosis GO:0006909 215 0.020
organelle fission GO:0048285 340 0.020
carbohydrate derivative catabolic process GO:1901136 118 0.020
mesenchymal cell differentiation GO:0048762 1 0.020
positive regulation of signal transduction GO:0009967 223 0.020
nucleoside phosphate catabolic process GO:1901292 110 0.020
ribonucleoside triphosphate catabolic process GO:0009203 108 0.020
regulation of cellular amino acid metabolic process GO:0006521 0 0.020
regulation of hydrolase activity GO:0051336 97 0.020
purine containing compound catabolic process GO:0072523 112 0.019
detection of stimulus GO:0051606 156 0.019
enzyme linked receptor protein signaling pathway GO:0007167 179 0.019
single organism cell adhesion GO:0098602 47 0.019
organonitrogen compound biosynthetic process GO:1901566 117 0.019
response to other organism GO:0051707 293 0.019
oocyte anterior posterior axis specification GO:0007314 72 0.019
death GO:0016265 284 0.019
organonitrogen compound catabolic process GO:1901565 128 0.019
glycosyl compound metabolic process GO:1901657 127 0.019
anatomical structure homeostasis GO:0060249 97 0.019
sensory perception GO:0007600 196 0.019
regulation of phosphorylation GO:0042325 147 0.019
response to ionizing radiation GO:0010212 32 0.018
regulation of cellular ketone metabolic process GO:0010565 3 0.018
regulation of small gtpase mediated signal transduction GO:0051056 93 0.018
regulation of cell death GO:0010941 173 0.018
purine ribonucleotide catabolic process GO:0009154 109 0.018
developmental maturation GO:0021700 172 0.018
sensory perception of mechanical stimulus GO:0050954 72 0.018
positive regulation of cell differentiation GO:0045597 64 0.018
response to lipopolysaccharide GO:0032496 4 0.018
imaginal disc derived wing morphogenesis GO:0007476 337 0.018
anion homeostasis GO:0055081 3 0.018
oocyte construction GO:0007308 112 0.018
vesicle mediated transport GO:0016192 381 0.018
humoral immune response GO:0006959 117 0.018
regulation of localization GO:0032879 275 0.017
oocyte differentiation GO:0009994 145 0.017
microtubule polymerization or depolymerization GO:0031109 39 0.017
adult behavior GO:0030534 137 0.017
cellular nitrogen compound catabolic process GO:0044270 165 0.017
segmentation GO:0035282 207 0.017
Fly
ras protein signal transduction GO:0007265 88 0.017
macromolecular complex assembly GO:0065003 256 0.017
open tracheal system development GO:0007424 204 0.017
Fly
organophosphate catabolic process GO:0046434 112 0.017
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.017
salivary gland morphogenesis GO:0007435 145 0.017
response to external biotic stimulus GO:0043207 293 0.017
cytoskeleton dependent cytokinesis GO:0061640 81 0.016
regulation of nervous system development GO:0051960 248 0.016
Fly
spindle organization GO:0007051 253 0.016
regulation of programmed cell death GO:0043067 152 0.016
small gtpase mediated signal transduction GO:0007264 88 0.016
cellular component disassembly GO:0022411 46 0.016
imaginal disc pattern formation GO:0007447 91 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.016
cellular protein complex disassembly GO:0043624 35 0.016
positive regulation of phosphorylation GO:0042327 87 0.016
homeostatic process GO:0042592 199 0.016
regulation of cell proliferation GO:0042127 163 0.016
negative regulation of cell communication GO:0010648 223 0.016
Fly
positive regulation of transport GO:0051050 92 0.016
negative regulation of cell cycle GO:0045786 116 0.016
regulation of cytoskeleton organization GO:0051493 89 0.016
immune response regulating signaling pathway GO:0002764 2 0.016
retina development in camera type eye GO:0060041 4 0.015
response to oxygen containing compound GO:1901700 200 0.015
hair cell differentiation GO:0035315 47 0.015
morphogenesis of follicular epithelium GO:0016333 36 0.015
protein localization GO:0008104 284 0.015
purine nucleotide catabolic process GO:0006195 109 0.015
nephron epithelium development GO:0072009 3 0.015
regulation of cell projection organization GO:0031344 92 0.015
Fly
protein complex disassembly GO:0043241 36 0.015
immune effector process GO:0002252 98 0.015
centrosome organization GO:0051297 163 0.015
gtp metabolic process GO:0046039 72 0.015
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.014
Fly
oocyte development GO:0048599 124 0.014
negative regulation of programmed cell death GO:0043069 72 0.014
ribonucleotide catabolic process GO:0009261 109 0.014
mapk cascade GO:0000165 107 0.014
cytokinesis GO:0000910 90 0.014
cellular amine metabolic process GO:0044106 12 0.014
guanosine containing compound metabolic process GO:1901068 74 0.014
oocyte axis specification GO:0007309 108 0.014
single organism cellular localization GO:1902580 180 0.014
positive regulation of mapk cascade GO:0043410 63 0.014
regulation of tube length open tracheal system GO:0035159 24 0.014
Fly
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.014
protein modification by small protein conjugation or removal GO:0070647 106 0.014
response to biotic stimulus GO:0009607 294 0.014
positive regulation of cell motility GO:2000147 3 0.014
positive regulation of cell migration GO:0030335 2 0.014
intracellular transport GO:0046907 228 0.014
epidermal growth factor receptor signaling pathway GO:0007173 58 0.014
chaeta development GO:0022416 97 0.014
regulation of developmental growth GO:0048638 174 0.014
mitotic cytokinesis GO:0000281 50 0.014
positive regulation of cell development GO:0010720 61 0.014
regulation of ras protein signal transduction GO:0046578 93 0.014
positive regulation of retinal cell programmed cell death GO:0046670 9 0.014
single organism intracellular transport GO:1902582 207 0.014
gtp catabolic process GO:0006184 72 0.014
camera type eye morphogenesis GO:0048593 2 0.014
developmental programmed cell death GO:0010623 138 0.014
proteolysis GO:0006508 192 0.014
regulation of microtubule based process GO:0032886 49 0.014
regulation of cell cycle GO:0051726 291 0.014
regulation of catabolic process GO:0009894 170 0.014
microtubule based transport GO:0010970 42 0.014
negative regulation of notch signaling pathway GO:0045746 41 0.013
Fly
anterior posterior axis specification GO:0009948 109 0.013
exocrine system development GO:0035272 162 0.013
synaptic transmission GO:0007268 288 0.013
Fly
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.013
monocarboxylic acid transport GO:0015718 3 0.013
positive regulation of cell death GO:0010942 69 0.013
amine metabolic process GO:0009308 12 0.013
actomyosin contractile ring organization GO:0044837 10 0.013
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 4 0.013
taxis GO:0042330 304 0.013
Fly
transcription from rna polymerase ii promoter GO:0006366 368 0.013
signal transduction by phosphorylation GO:0023014 107 0.013
defense response GO:0006952 300 0.013
innate immune response GO:0045087 144 0.013
protein complex biogenesis GO:0070271 201 0.013
respiratory system development GO:0060541 213 0.013
Fly
regulation of cell cycle process GO:0010564 181 0.013
negative regulation of signal transduction GO:0009968 206 0.013
Fly
cellular lipid metabolic process GO:0044255 83 0.013
mesenchymal cell development GO:0014031 1 0.013
organic substance transport GO:0071702 257 0.013
positive regulation of nucleotide catabolic process GO:0030813 46 0.013
regulation of mapk cascade GO:0043408 92 0.012
lipid metabolic process GO:0006629 121 0.012
sensory perception of sound GO:0007605 56 0.012
positive regulation of intracellular signal transduction GO:1902533 116 0.012
dna methylation GO:0006306 4 0.012
cuticle development GO:0042335 86 0.012
kidney morphogenesis GO:0060993 3 0.012
positive regulation of immune system process GO:0002684 68 0.012
chaeta morphogenesis GO:0008407 42 0.012
regulation of actin filament based process GO:0032970 42 0.012
circulatory system process GO:0003013 37 0.012
g protein coupled receptor signaling pathway GO:0007186 136 0.012
positive regulation of protein metabolic process GO:0051247 128 0.012
negative regulation of multicellular organismal process GO:0051241 142 0.012
negative regulation of gene expression GO:0010629 387 0.012
telencephalon development GO:0021537 2 0.012
hematopoietic progenitor cell differentiation GO:0002244 1 0.012
salivary gland development GO:0007431 162 0.012
stem cell differentiation GO:0048863 117 0.012
dorsal ventral pattern formation GO:0009953 133 0.012
negative regulation of cellular component organization GO:0051129 108 0.012
regulation of apoptotic process GO:0042981 130 0.012
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.012
defense response to bacterium GO:0042742 178 0.012
rna methylation GO:0001510 2 0.012
heterochromatin organization GO:0070828 25 0.012
mitotic spindle organization GO:0007052 220 0.012
positive regulation of immune response GO:0050778 63 0.012
cellular response to dna damage stimulus GO:0006974 223 0.012
embryonic axis specification GO:0000578 107 0.012
immune response activating signal transduction GO:0002757 2 0.012
positive regulation of cellular protein metabolic process GO:0032270 118 0.012
positive regulation of gene expression GO:0010628 290 0.012
response to radiation GO:0009314 155 0.012
connective tissue development GO:0061448 3 0.012
nuclear division GO:0000280 332 0.012
tube morphogenesis GO:0035239 191 0.012
rhythmic process GO:0048511 106 0.011
regulation of anatomical structure morphogenesis GO:0022603 242 0.011
Fly
pigmentation GO:0043473 75 0.011
leg disc development GO:0035218 92 0.011
axon development GO:0061564 297 0.011
Fly
epidermis development GO:0008544 65 0.011
skeletal muscle fiber development GO:0048741 3 0.011
tube development GO:0035295 244 0.011
mitotic nuclear division GO:0007067 213 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.011
dna methylation or demethylation GO:0044728 4 0.011
regulation of transport GO:0051049 181 0.011
pole plasm assembly GO:0007315 61 0.011
peptide metabolic process GO:0006518 80 0.011
regulation of endocytosis GO:0030100 37 0.011
positive regulation of protein modification process GO:0031401 58 0.011
protein depolymerization GO:0051261 31 0.011
regulation of epithelial cell differentiation GO:0030856 4 0.011
regulation of cellular localization GO:0060341 136 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.011
regulation of organelle organization GO:0033043 196 0.011
imaginal disc derived leg morphogenesis GO:0007480 80 0.011
regulation of reproductive process GO:2000241 54 0.011
neuron projection guidance GO:0097485 241 0.011
Fly
autophagic cell death GO:0048102 83 0.011
molting cycle chitin based cuticle GO:0007591 56 0.010
chemotaxis GO:0006935 249 0.010
Fly
water homeostasis GO:0030104 3 0.010
regulation of mitotic cell cycle GO:0007346 190 0.010
positive regulation of gtp catabolic process GO:0033126 43 0.010
protein heterooligomerization GO:0051291 4 0.010
positive regulation of biosynthetic process GO:0009891 316 0.010
protein complex assembly GO:0006461 200 0.010
regulation of cell substrate adhesion GO:0010810 2 0.010
regulation of neuron differentiation GO:0045664 103 0.010
Fly
non sensory hair organization GO:0035316 47 0.010
mrna processing GO:0006397 104 0.010
regulation of actin cytoskeleton organization GO:0032956 42 0.010
somatic muscle development GO:0007525 66 0.010
regulation of cell morphogenesis GO:0022604 163 0.010
Fly
positive regulation of transcription dna templated GO:0045893 266 0.010
ribonucleoside monophosphate catabolic process GO:0009158 39 0.010
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.010
cellular response to chemical stimulus GO:0070887 199 0.010
positive regulation of cellular amine metabolic process GO:0033240 0 0.010

Cad74A disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.027
nervous system disease DOID:863 0 0.013
disease of metabolism DOID:0014667 0 0.010
inherited metabolic disorder DOID:655 0 0.010