Drosophila melanogaster

135 known processes

lsn (Dmel_CG6637)

larsen

(Aliases: Vps22,vps22,Dmel\CG6637,CG6637)

lsn biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 8 0.987
endosome transport via multivesicular body sorting pathway GO:0032509 12 0.975
oocyte differentiation GO:0009994 145 0.868
oocyte development GO:0048599 124 0.719
oocyte construction GO:0007308 112 0.662
oocyte axis specification GO:0007309 108 0.649
cellular macromolecule localization GO:0070727 220 0.553
vacuolar transport GO:0007034 13 0.542
membrane organization GO:0061024 112 0.490
sex differentiation GO:0007548 81 0.488
vesicle organization GO:0016050 44 0.475
protein catabolic process GO:0030163 101 0.386
carbohydrate derivative metabolic process GO:1901135 217 0.386
germarium derived egg chamber formation GO:0007293 101 0.381
regionalization GO:0003002 416 0.370
negative regulation of response to stimulus GO:0048585 258 0.347
modification dependent protein catabolic process GO:0019941 78 0.334
cellular macromolecule catabolic process GO:0044265 136 0.318
regulation of notch signaling pathway GO:0008593 100 0.290
single organism membrane organization GO:0044802 93 0.265
ribonucleoside triphosphate metabolic process GO:0009199 119 0.241
cell proliferation GO:0008283 299 0.240
establishment of localization in cell GO:0051649 402 0.228
purine ribonucleotide metabolic process GO:0009150 145 0.221
regulation of cell cycle GO:0051726 291 0.212
cellular protein localization GO:0034613 160 0.209
localization of cell GO:0051674 257 0.203
pole plasm assembly GO:0007315 61 0.200
cellular protein catabolic process GO:0044257 83 0.195
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.194
anterior posterior axis specification embryo GO:0008595 103 0.193
germ line cyst formation GO:0048134 44 0.193
cell migration GO:0016477 238 0.192
organonitrogen compound metabolic process GO:1901564 318 0.188
ribose phosphate metabolic process GO:0019693 145 0.186
notch signaling pathway GO:0007219 120 0.180
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.177
germarium derived female germ line cyst formation GO:0030727 42 0.176
macromolecule catabolic process GO:0009057 161 0.176
single organism intracellular transport GO:1902582 207 0.174
endocytosis GO:0006897 310 0.173
catabolic process GO:0009056 409 0.172
modification dependent macromolecule catabolic process GO:0043632 79 0.169
purine nucleoside metabolic process GO:0042278 127 0.166
embryo development ending in birth or egg hatching GO:0009792 152 0.155
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.153
anterior posterior pattern specification GO:0009952 136 0.153
organelle assembly GO:0070925 198 0.149
membrane budding GO:0006900 4 0.148
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.142
pole plasm oskar mrna localization GO:0045451 46 0.141
organelle membrane fusion GO:0090174 16 0.140
columnar cuboidal epithelial cell development GO:0002066 249 0.135
oocyte fate determination GO:0030716 27 0.132
organophosphate metabolic process GO:0019637 195 0.129
programmed cell death GO:0012501 257 0.127
embryonic pattern specification GO:0009880 174 0.125
ribonucleoside metabolic process GO:0009119 127 0.124
axis specification GO:0009798 167 0.124
regulation of cell proliferation GO:0042127 163 0.123
developmental maturation GO:0021700 172 0.123
response to organic substance GO:0010033 284 0.122
regulation of localization GO:0032879 275 0.122
cellular response to extracellular stimulus GO:0031668 64 0.116
cytoplasmic transport GO:0016482 130 0.114
eye development GO:0001654 323 0.112
cell motility GO:0048870 251 0.109
single organism cellular localization GO:1902580 180 0.108
cellular protein complex disassembly GO:0043624 35 0.105
response to extracellular stimulus GO:0009991 116 0.102
protein modification process GO:0036211 438 0.101
pole plasm mrna localization GO:0019094 49 0.097
endosomal transport GO:0016197 44 0.097
reproductive structure development GO:0048608 74 0.094
ubiquitin dependent protein catabolic process GO:0006511 78 0.094
epithelial cell differentiation GO:0030855 322 0.094
response to nutrient levels GO:0031667 114 0.093
cytoplasm organization GO:0007028 64 0.093
cell maturation GO:0048469 144 0.091
nucleotide metabolic process GO:0009117 161 0.091
female germ line cyst formation GO:0048135 42 0.090
secretion GO:0046903 109 0.088
protein localization to organelle GO:0033365 82 0.088
positive regulation of cell communication GO:0010647 250 0.087
nucleotide catabolic process GO:0009166 109 0.087
segmentation GO:0035282 207 0.087
smoothened signaling pathway GO:0007224 49 0.087
nucleoside triphosphate metabolic process GO:0009141 120 0.086
glycosyl compound metabolic process GO:1901657 127 0.085
epithelial cell development GO:0002064 274 0.085
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.083
nucleoside metabolic process GO:0009116 127 0.081
ovarian follicle cell development GO:0030707 248 0.081
early endosome to late endosome transport GO:0045022 3 0.080
blastoderm segmentation GO:0007350 159 0.078
proteolysis GO:0006508 192 0.078
regulation of multi organism process GO:0043900 131 0.076
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.075
secretion by cell GO:0032940 101 0.072
nucleobase containing small molecule metabolic process GO:0055086 174 0.070
purine containing compound metabolic process GO:0072521 155 0.069
macroautophagy GO:0016236 42 0.068
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.067
vesicle mediated transport GO:0016192 381 0.067
purine nucleoside triphosphate catabolic process GO:0009146 108 0.066
purine containing compound catabolic process GO:0072523 112 0.064
oocyte anterior posterior axis specification GO:0007314 72 0.064
regulation of catabolic process GO:0009894 170 0.064
regulation of response to stress GO:0080134 200 0.062
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.062
purine nucleoside triphosphate metabolic process GO:0009144 119 0.060
cell death GO:0008219 279 0.058
reproductive system development GO:0061458 74 0.057
establishment of oocyte nucleus localization involved in oocyte dorsal ventral axis specification GO:0030722 6 0.057
organic substance catabolic process GO:1901575 308 0.055
apoptotic process GO:0006915 159 0.055
regulation of cellular localization GO:0060341 136 0.055
negative regulation of cellular metabolic process GO:0031324 382 0.054
establishment or maintenance of cell polarity GO:0007163 167 0.054
regulation of organelle organization GO:0033043 196 0.053
regulation of mitotic cell cycle phase transition GO:1901990 130 0.053
negative regulation of gene expression epigenetic GO:0045814 77 0.053
purine nucleotide metabolic process GO:0006163 146 0.052
nucleoside phosphate catabolic process GO:1901292 110 0.052
endomembrane system organization GO:0010256 119 0.052
negative regulation of gene expression GO:0010629 387 0.051
ribonucleotide metabolic process GO:0009259 145 0.051
germarium derived oocyte differentiation GO:0030706 29 0.050
phagocytosis GO:0006909 215 0.050
regulation of transport GO:0051049 181 0.050
single organism biosynthetic process GO:0044711 206 0.050
immune system process GO:0002376 347 0.047
negative regulation of biosynthetic process GO:0009890 277 0.047
glycosyl compound catabolic process GO:1901658 112 0.046
body morphogenesis GO:0010171 2 0.046
positive regulation of phosphorus metabolic process GO:0010562 139 0.046
regulation of endocytosis GO:0030100 37 0.045
purine nucleotide catabolic process GO:0006195 109 0.045
regulation of cell development GO:0060284 215 0.045
axon development GO:0061564 297 0.044
positive regulation of macromolecule metabolic process GO:0010604 405 0.044
positive regulation of response to stimulus GO:0048584 323 0.044
nucleoside catabolic process GO:0009164 112 0.043
cellular response to external stimulus GO:0071496 66 0.042
organic cyclic compound catabolic process GO:1901361 168 0.042
purine ribonucleoside catabolic process GO:0046130 112 0.041
negative regulation of cell proliferation GO:0008285 69 0.040
maternal determination of anterior posterior axis embryo GO:0008358 74 0.040
rna localization GO:0006403 115 0.039
protein localization GO:0008104 284 0.039
heterocycle catabolic process GO:0046700 166 0.038
regulation of cell death GO:0010941 173 0.038
death GO:0016265 284 0.038
regulation of pole plasm oskar mrna localization GO:0007317 27 0.037
central nervous system development GO:0007417 201 0.037
cellular response to nutrient levels GO:0031669 62 0.037
regulation of phosphate metabolic process GO:0019220 210 0.036
regulation of vesicle mediated transport GO:0060627 59 0.036
ribonucleoside triphosphate catabolic process GO:0009203 108 0.035
cellular response to organic substance GO:0071310 132 0.035
nucleoside phosphate metabolic process GO:0006753 162 0.035
nucleoside triphosphate catabolic process GO:0009143 108 0.034
organophosphate catabolic process GO:0046434 112 0.034
nuclear migration GO:0007097 20 0.033
small molecule metabolic process GO:0044281 305 0.033
nucleobase containing compound catabolic process GO:0034655 165 0.033
spindle organization GO:0007051 253 0.033
regulation of apoptotic process GO:0042981 130 0.033
phosphorylation GO:0016310 294 0.032
regulation of phosphorus metabolic process GO:0051174 210 0.032
regulation of growth GO:0040008 233 0.032
purine ribonucleoside metabolic process GO:0046128 127 0.031
purine nucleoside catabolic process GO:0006152 112 0.031
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.031
guanosine containing compound catabolic process GO:1901069 74 0.031
positive regulation of phosphate metabolic process GO:0045937 139 0.030
oocyte nucleus localization involved in oocyte dorsal ventral axis specification GO:0051663 12 0.030
negative regulation of rna biosynthetic process GO:1902679 240 0.030
establishment or maintenance of polarity of follicular epithelium GO:0016334 26 0.030
negative regulation of cellular biosynthetic process GO:0031327 277 0.030
small gtpase mediated signal transduction GO:0007264 88 0.029
development of primary sexual characteristics GO:0045137 50 0.029
protein targeting GO:0006605 64 0.029
ribonucleotide catabolic process GO:0009261 109 0.029
phagocytosis engulfment GO:0006911 11 0.029
gonad development GO:0008406 50 0.029
scf dependent proteasomal ubiquitin dependent protein catabolic process GO:0031146 1 0.028
positive regulation of neurogenesis GO:0050769 41 0.028
tripartite regional subdivision GO:0007351 103 0.027
negative regulation of mitotic cell cycle GO:0045930 109 0.027
regulation of cell differentiation GO:0045595 302 0.027
regulation of mapk cascade GO:0043408 92 0.027
membrane fusion GO:0061025 42 0.027
negative regulation of transcription dna templated GO:0045892 237 0.027
positive regulation of intracellular signal transduction GO:1902533 116 0.026
molting cycle GO:0042303 56 0.026
cellular protein modification process GO:0006464 438 0.026
regulation of neuron differentiation GO:0045664 103 0.026
pole plasm rna localization GO:0007316 52 0.026
chromatin silencing GO:0006342 76 0.026
cellular response to starvation GO:0009267 61 0.025
carbohydrate derivative catabolic process GO:1901136 118 0.025
pigmentation GO:0043473 75 0.024
cellular macromolecular complex assembly GO:0034622 153 0.024
negative regulation of cell cycle process GO:0010948 109 0.024
macromolecular complex assembly GO:0065003 256 0.024
larval development GO:0002164 104 0.023
regulation of protein metabolic process GO:0051246 256 0.023
positive regulation of protein metabolic process GO:0051247 128 0.023
response to starvation GO:0042594 97 0.023
ras protein signal transduction GO:0007265 88 0.023
pronuclear migration GO:0035046 4 0.023
regulation of small gtpase mediated signal transduction GO:0051056 93 0.022
oocyte microtubule cytoskeleton polarization GO:0008103 22 0.022
organic substance transport GO:0071702 257 0.022
ribonucleoside catabolic process GO:0042454 112 0.022
protein modification by small protein conjugation or removal GO:0070647 106 0.022
dendrite morphogenesis GO:0048813 199 0.022
purine ribonucleotide catabolic process GO:0009154 109 0.022
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.021
positive regulation of signaling GO:0023056 243 0.021
protein transport GO:0015031 155 0.021
protein complex assembly GO:0006461 200 0.021
regulation of ras protein signal transduction GO:0046578 93 0.020
negative regulation of nucleic acid templated transcription GO:1903507 240 0.019
establishment of protein localization to organelle GO:0072594 62 0.019
protein ubiquitination GO:0016567 70 0.019
positive regulation of catabolic process GO:0009896 105 0.019
regulation of response to external stimulus GO:0032101 115 0.019
positive regulation of biosynthetic process GO:0009891 316 0.018
response to endogenous stimulus GO:0009719 119 0.018
cellular nitrogen compound catabolic process GO:0044270 165 0.018
organonitrogen compound biosynthetic process GO:1901566 117 0.018
atp metabolic process GO:0046034 49 0.018
regulation of neurogenesis GO:0050767 158 0.018
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.018
positive regulation of cellular protein metabolic process GO:0032270 118 0.018
regulation of cytoskeleton organization GO:0051493 89 0.018
cellular response to chemical stimulus GO:0070887 199 0.018
cellular catabolic process GO:0044248 372 0.018
oocyte dorsal ventral axis specification GO:0007310 34 0.017
intracellular mrna localization GO:0008298 66 0.017
immune response GO:0006955 246 0.017
axonogenesis GO:0007409 290 0.017
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 29 0.017
protein modification by small protein conjugation GO:0032446 79 0.017
border follicle cell migration GO:0007298 113 0.017
intracellular transport GO:0046907 228 0.017
regulation of protein modification process GO:0031399 112 0.017
male sex differentiation GO:0046661 25 0.017
macromolecular complex disassembly GO:0032984 37 0.016
growth GO:0040007 359 0.016
autophagic vacuole assembly GO:0000045 2 0.016
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.015
exocytosis GO:0006887 28 0.015
mapk cascade GO:0000165 107 0.015
regulation of gene expression epigenetic GO:0040029 128 0.014
rna processing GO:0006396 147 0.014
regulation of epithelial cell proliferation GO:0050678 4 0.014
anterior posterior axis specification GO:0009948 109 0.014
positive regulation of signal transduction GO:0009967 223 0.014
meiotic cell cycle GO:0051321 171 0.014
chromosome organization GO:0051276 360 0.014
regulation of secretion GO:0051046 44 0.014
ribonucleoside monophosphate metabolic process GO:0009161 51 0.014
germarium derived oocyte fate determination GO:0007294 26 0.013
negative regulation of epithelial cell proliferation GO:0050680 4 0.013
negative regulation of organelle organization GO:0010639 56 0.013
establishment of protein localization GO:0045184 163 0.013
nitrogen compound transport GO:0071705 85 0.013
negative regulation of cell cycle GO:0045786 116 0.013
positive regulation of chromatin modification GO:1903310 17 0.013
lateral inhibition GO:0046331 206 0.013
negative regulation of erbb signaling pathway GO:1901185 29 0.013
regulation of molecular function GO:0065009 217 0.012
protein processing GO:0016485 68 0.012
intracellular signal transduction GO:0035556 300 0.012
negative regulation of apoptotic process GO:0043066 63 0.012
gtp catabolic process GO:0006184 72 0.012
organonitrogen compound catabolic process GO:1901565 128 0.012
aromatic compound catabolic process GO:0019439 166 0.012
regulation of microtubule based process GO:0032886 49 0.012
endosome organization GO:0007032 9 0.012
negative regulation of cell communication GO:0010648 223 0.012
regulation of cell cycle process GO:0010564 181 0.012
regulation of multicellular organismal development GO:2000026 414 0.012
positive regulation of rna biosynthetic process GO:1902680 266 0.012
establishment or maintenance of bipolar cell polarity GO:0061245 34 0.012
hatching GO:0035188 4 0.012
genitalia development GO:0048806 26 0.011
wnt signaling pathway GO:0016055 98 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.011
eye morphogenesis GO:0048592 260 0.011
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 1 0.011
transcription from rna polymerase ii promoter GO:0006366 368 0.011
positive regulation of cellular catabolic process GO:0031331 95 0.011
erbb signaling pathway GO:0038127 58 0.011
positive regulation of molecular function GO:0044093 136 0.011
negative regulation of cell death GO:0060548 81 0.010
regulation of proteolysis GO:0030162 87 0.010
positive regulation of transport GO:0051050 92 0.010
glycosyl compound biosynthetic process GO:1901659 3 0.010
purine nucleoside monophosphate metabolic process GO:0009126 50 0.010
regulation of catalytic activity GO:0050790 185 0.010
cell cycle checkpoint GO:0000075 95 0.010
regulation of mitotic cell cycle GO:0007346 190 0.010
histone lysine methylation GO:0034968 32 0.010
chemotaxis GO:0006935 249 0.010
mitotic dna damage checkpoint GO:0044773 74 0.010
negative regulation of cellular component organization GO:0051129 108 0.010

lsn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.014