Drosophila melanogaster

63 known processes

mth (Dmel_CG6936)

methuselah

(Aliases: MTH,CG6936,Mth,Dmel\CG6936)

mth biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to oxidative stress GO:0006979 86 0.881
response to starvation GO:0042594 97 0.572
response to organic substance GO:0010033 284 0.460
response to reactive oxygen species GO:0000302 24 0.452
imaginal disc derived appendage morphogenesis GO:0035114 395 0.353
Fly
imaginal disc derived appendage development GO:0048737 399 0.299
Fly
cellular response to oxidative stress GO:0034599 28 0.287
regulation of protein metabolic process GO:0051246 256 0.277
appendage development GO:0048736 401 0.250
Fly
muscle cell differentiation GO:0042692 103 0.249
regulation of cellular ketone metabolic process GO:0010565 3 0.246
biological adhesion GO:0022610 138 0.234
imaginal disc derived wing morphogenesis GO:0007476 337 0.229
Fly
programmed cell death GO:0012501 257 0.224
positive regulation of cell development GO:0010720 61 0.218
post embryonic appendage morphogenesis GO:0035120 385 0.214
Fly
synaptic transmission GO:0007268 288 0.204
positive regulation of signaling GO:0023056 243 0.202
single organism behavior GO:0044708 391 0.201
amine metabolic process GO:0009308 12 0.196
regulation of cell development GO:0060284 215 0.195
cellular amine metabolic process GO:0044106 12 0.186
cell adhesion GO:0007155 136 0.175
neurotransmitter secretion GO:0007269 35 0.173
regulation of nervous system development GO:0051960 248 0.168
organonitrogen compound metabolic process GO:1901564 318 0.162
regulation of cellular amino acid metabolic process GO:0006521 0 0.161
negative regulation of multicellular organismal process GO:0051241 142 0.161
wing disc morphogenesis GO:0007472 344 0.159
Fly
axonogenesis GO:0007409 290 0.155
regulation of cell projection organization GO:0031344 92 0.154
regulation of multi organism process GO:0043900 131 0.153
regulation of cell differentiation GO:0045595 302 0.152
multicellular organismal aging GO:0010259 140 0.151
homeostatic process GO:0042592 199 0.150
response to abiotic stimulus GO:0009628 341 0.149
negative regulation of signaling GO:0023057 219 0.148
cellular response to chemical stimulus GO:0070887 199 0.147
response to osmotic stress GO:0006970 14 0.146
carbohydrate metabolic process GO:0005975 82 0.145
small molecule metabolic process GO:0044281 305 0.144
cell adhesion involved in heart morphogenesis GO:0061343 12 0.142
response to radiation GO:0009314 155 0.140
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.137
neurological system process GO:0050877 358 0.136
positive regulation of cell migration GO:0030335 2 0.135
response to nutrient levels GO:0031667 114 0.129
defense response GO:0006952 300 0.128
embryonic morphogenesis GO:0048598 206 0.127
Fly
response to hydrogen peroxide GO:0042542 11 0.127
regulation of multicellular organismal development GO:2000026 414 0.125
striated muscle cell differentiation GO:0051146 90 0.125
regulation of neuron projection development GO:0010975 69 0.120
negative regulation of cell communication GO:0010648 223 0.115
appendage morphogenesis GO:0035107 397 0.115
Fly
regulation of cellular amine metabolic process GO:0033238 3 0.111
positive regulation of cell communication GO:0010647 250 0.110
axon development GO:0061564 297 0.109
cardiovascular system development GO:0072358 82 0.109
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.108
heart development GO:0007507 82 0.102
apoptotic process GO:0006915 159 0.098
death GO:0016265 284 0.097
secretion GO:0046903 109 0.097
circulatory system development GO:0072359 82 0.096
syncytium formation GO:0006949 43 0.095
central nervous system development GO:0007417 201 0.095
positive regulation of cell motility GO:2000147 3 0.094
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.091
cell death GO:0008219 279 0.090
negative regulation of response to stimulus GO:0048585 258 0.090
morphogenesis of an epithelium GO:0002009 276 0.090
negative regulation of cell development GO:0010721 62 0.089
catabolic process GO:0009056 409 0.088
regulation of cellular localization GO:0060341 136 0.087
mapk cascade GO:0000165 107 0.087
negative regulation of developmental process GO:0051093 201 0.082
forebrain development GO:0030900 2 0.082
small gtpase mediated signal transduction GO:0007264 88 0.082
response to oxygen containing compound GO:1901700 200 0.082
synaptic vesicle transport GO:0048489 50 0.081
vesicle localization GO:0051648 55 0.079
positive regulation of catabolic process GO:0009896 105 0.079
regulation of neuron differentiation GO:0045664 103 0.078
morphogenesis of embryonic epithelium GO:0016331 94 0.077
learning or memory GO:0007611 141 0.077
cellular carbohydrate metabolic process GO:0044262 22 0.076
dendrite development GO:0016358 204 0.076
regulation of neurogenesis GO:0050767 158 0.075
negative regulation of protein metabolic process GO:0051248 85 0.075
cell maturation GO:0048469 144 0.075
adult behavior GO:0030534 137 0.075
septate junction assembly GO:0019991 26 0.075
response to other organism GO:0051707 293 0.075
response to metal ion GO:0010038 23 0.073
regulation of response to oxidative stress GO:1902882 4 0.072
positive regulation of response to stimulus GO:0048584 323 0.072
regulation of intracellular signal transduction GO:1902531 236 0.072
positive regulation of multicellular organismal process GO:0051240 143 0.072
oxoacid metabolic process GO:0043436 103 0.071
negative regulation of cellular component organization GO:0051129 108 0.071
response to inorganic substance GO:0010035 44 0.071
regulation of protein serine threonine kinase activity GO:0071900 25 0.071
regulation of localization GO:0032879 275 0.070
positive regulation of neurogenesis GO:0050769 41 0.070
myotube cell development GO:0014904 3 0.070
regulation of anatomical structure morphogenesis GO:0022603 242 0.069
regulation of cell maturation GO:1903429 27 0.068
intracellular signal transduction GO:0035556 300 0.068
immune system process GO:0002376 347 0.068
tissue morphogenesis GO:0048729 297 0.067
Fly
regulation of immune system process GO:0002682 176 0.066
dorsal closure GO:0007391 79 0.066
tissue homeostasis GO:0001894 36 0.066
endocytosis GO:0006897 310 0.065
synaptic vesicle exocytosis GO:0016079 16 0.065
localization of cell GO:0051674 257 0.065
organic hydroxy compound metabolic process GO:1901615 83 0.064
peptidyl amino acid modification GO:0018193 105 0.064
regulation of cellular protein metabolic process GO:0032268 243 0.064
axon guidance GO:0007411 233 0.063
transmembrane transport GO:0055085 139 0.062
cellular amino acid metabolic process GO:0006520 61 0.062
regulation of map kinase activity GO:0043405 17 0.062
neuromuscular synaptic transmission GO:0007274 67 0.061
response to light stimulus GO:0009416 124 0.061
response to ethanol GO:0045471 59 0.061
positive regulation of cell differentiation GO:0045597 64 0.059
protein localization GO:0008104 284 0.059
cellular response to organic substance GO:0071310 132 0.059
regulation of cell death GO:0010941 173 0.059
regulation of response to stress GO:0080134 200 0.059
regulation of protein kinase activity GO:0045859 51 0.058
cell migration GO:0016477 238 0.058
oocyte maturation GO:0001556 3 0.056
muscle structure development GO:0061061 224 0.055
cellular catabolic process GO:0044248 372 0.055
associative learning GO:0008306 65 0.054
neuron projection guidance GO:0097485 241 0.054
cell proliferation GO:0008283 299 0.054
heart morphogenesis GO:0003007 32 0.053
myotube differentiation GO:0014902 46 0.053
regulation of mapk cascade GO:0043408 92 0.053
regulation of cellular response to oxidative stress GO:1900407 4 0.053
organic acid metabolic process GO:0006082 103 0.052
actomyosin structure organization GO:0031032 56 0.052
response to organophosphorus GO:0046683 2 0.052
establishment of organelle localization GO:0051656 122 0.052
establishment of localization in cell GO:0051649 402 0.051
cellular macromolecule catabolic process GO:0044265 136 0.051
regulation of catabolic process GO:0009894 170 0.051
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.050
respiratory system development GO:0060541 213 0.050
oocyte differentiation GO:0009994 145 0.049
single organismal cell cell adhesion GO:0016337 45 0.049
lipid metabolic process GO:0006629 121 0.049
cellular response to dna damage stimulus GO:0006974 223 0.048
regulation of synapse organization GO:0050807 110 0.048
oocyte development GO:0048599 124 0.047
cation homeostasis GO:0055080 51 0.047
positive regulation of secretion GO:0051047 22 0.047
response to monosaccharide GO:0034284 4 0.046
regulation of transport GO:0051049 181 0.046
cellular ketone metabolic process GO:0042180 24 0.046
regulation of reproductive process GO:2000241 54 0.045
chemotaxis GO:0006935 249 0.045
macromolecule catabolic process GO:0009057 161 0.045
phenol containing compound metabolic process GO:0018958 57 0.044
enzyme linked receptor protein signaling pathway GO:0007167 179 0.044
organic substance catabolic process GO:1901575 308 0.044
regulation of behavior GO:0050795 75 0.044
carboxylic acid metabolic process GO:0019752 92 0.044
aging GO:0007568 143 0.043
mucosal immune response GO:0002385 10 0.043
positive regulation of immune system process GO:0002684 68 0.043
macromolecular complex assembly GO:0065003 256 0.043
organophosphate metabolic process GO:0019637 195 0.042
response to glucose GO:0009749 2 0.041
gland development GO:0048732 191 0.041
protein complex assembly GO:0006461 200 0.041
imaginal disc derived wing hair organization GO:0035317 45 0.040
regulation of cellular component biogenesis GO:0044087 201 0.040
embryonic development via the syncytial blastoderm GO:0001700 148 0.040
neuron recognition GO:0008038 101 0.039
positive regulation of developmental process GO:0051094 143 0.039
regulation of protein modification process GO:0031399 112 0.039
positive regulation of macromolecule metabolic process GO:0010604 405 0.039
positive regulation of cell projection organization GO:0031346 29 0.039
salivary gland development GO:0007431 162 0.039
positive regulation of nervous system development GO:0051962 69 0.039
negative regulation of phosphorus metabolic process GO:0010563 45 0.038
organelle fission GO:0048285 340 0.038
tube development GO:0035295 244 0.038
Fly
single organism cell adhesion GO:0098602 47 0.038
determination of adult lifespan GO:0008340 137 0.037
positive regulation of cellular catabolic process GO:0031331 95 0.037
negative regulation of organelle organization GO:0010639 56 0.037
ameboidal type cell migration GO:0001667 151 0.037
cellular macromolecule localization GO:0070727 220 0.037
response to growth factor GO:0070848 31 0.036
organic substance transport GO:0071702 257 0.036
response to alcohol GO:0097305 95 0.036
regulation of membrane potential GO:0042391 35 0.036
positive regulation of cellular protein metabolic process GO:0032270 118 0.036
carbohydrate homeostasis GO:0033500 12 0.036
establishment of synaptic vesicle localization GO:0097480 50 0.036
positive regulation of cell death GO:0010942 69 0.035
positive regulation of intracellular signal transduction GO:1902533 116 0.035
mesoderm development GO:0007498 78 0.035
Fly
single organism catabolic process GO:0044712 228 0.035
ion transmembrane transport GO:0034220 122 0.035
anatomical structure homeostasis GO:0060249 97 0.035
positive regulation of cellular component organization GO:0051130 156 0.034
divalent metal ion transport GO:0070838 26 0.034
positive regulation of biosynthetic process GO:0009891 316 0.034
regulation of phosphorylation GO:0042325 147 0.034
negative regulation of peptidyl tyrosine phosphorylation GO:0050732 6 0.034
response to endogenous stimulus GO:0009719 119 0.034
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.033
epithelial cell development GO:0002064 274 0.033
membrane organization GO:0061024 112 0.033
cellular response to starvation GO:0009267 61 0.033
regulation of innate immune response GO:0045088 71 0.033
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.033
positive regulation of signal transduction GO:0009967 223 0.033
transcription from rna polymerase ii promoter GO:0006366 368 0.032
negative regulation of signal transduction GO:0009968 206 0.032
heterocycle catabolic process GO:0046700 166 0.032
developmental maturation GO:0021700 172 0.032
metal ion transport GO:0030001 74 0.032
myoblast fusion GO:0007520 43 0.031
negative regulation of cellular metabolic process GO:0031324 382 0.031
regulation of cell substrate adhesion GO:0010810 2 0.030
locomotory behavior GO:0007626 176 0.030
positive regulation of transcription dna templated GO:0045893 266 0.030
nucleobase containing compound catabolic process GO:0034655 165 0.030
protein complex biogenesis GO:0070271 201 0.029
aromatic compound catabolic process GO:0019439 166 0.029
epithelial cell differentiation GO:0030855 322 0.029
synapse organization GO:0050808 196 0.029
negative regulation of programmed cell death GO:0043069 72 0.029
signal release GO:0023061 49 0.029
protein localization to organelle GO:0033365 82 0.029
regulation of proteolysis GO:0030162 87 0.028
cellular response to growth factor stimulus GO:0071363 30 0.028
axon cargo transport GO:0008088 29 0.028
phosphorylation GO:0016310 294 0.028
vesicle mediated transport GO:0016192 381 0.028
single organism carbohydrate metabolic process GO:0044723 72 0.028
proteolysis GO:0006508 192 0.028
protein catabolic process GO:0030163 101 0.028
cellular response to endogenous stimulus GO:0071495 80 0.028
negative regulation of cellular protein metabolic process GO:0032269 85 0.028
immune response GO:0006955 246 0.028
negative regulation of neurogenesis GO:0050768 53 0.028
regulation of molecular function GO:0065009 217 0.028
brain development GO:0007420 120 0.028
positive regulation of programmed cell death GO:0043068 62 0.027
ras protein signal transduction GO:0007265 88 0.027
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.027
positive regulation of jun kinase activity GO:0043507 4 0.027
adult locomotory behavior GO:0008344 76 0.027
negative regulation of molecular function GO:0044092 51 0.027
positive regulation of lipid metabolic process GO:0045834 4 0.027
regulation of locomotion GO:0040012 42 0.027
regulation of response to external stimulus GO:0032101 115 0.027
hematopoietic or lymphoid organ development GO:0048534 57 0.026
positive regulation of apoptotic signaling pathway GO:2001235 4 0.026
positive regulation of protein metabolic process GO:0051247 128 0.026
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.026
response to hexose GO:0009746 3 0.026
positive regulation of phosphorus metabolic process GO:0010562 139 0.026
organelle assembly GO:0070925 198 0.026
phagocytosis GO:0006909 215 0.026
regulation of secretion GO:0051046 44 0.026
response to biotic stimulus GO:0009607 294 0.026
protein modification process GO:0036211 438 0.026
digestive system development GO:0055123 149 0.026
Fly
cell cycle phase transition GO:0044770 140 0.026
dephosphorylation GO:0016311 51 0.026
response to extracellular stimulus GO:0009991 116 0.025
open tracheal system development GO:0007424 204 0.025
negative regulation of cell differentiation GO:0045596 143 0.025
nitrogen compound transport GO:0071705 85 0.025
regulation of programmed cell death GO:0043067 152 0.025
cellular protein localization GO:0034613 160 0.025
nucleotide catabolic process GO:0009166 109 0.025
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.025
negative regulation of phosphate metabolic process GO:0045936 45 0.025
positive regulation of immune response GO:0050778 63 0.025
nucleoside phosphate catabolic process GO:1901292 110 0.025
autophagic vacuole assembly GO:0000045 2 0.025
lipid modification GO:0030258 24 0.024
cellular protein modification process GO:0006464 438 0.024
regulation of transferase activity GO:0051338 58 0.024
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.024
tube morphogenesis GO:0035239 191 0.024
Fly
sensory organ morphogenesis GO:0090596 260 0.024
purine ribonucleoside metabolic process GO:0046128 127 0.023
cell motility GO:0048870 251 0.023
regulation of cellular component movement GO:0051270 42 0.023
positive regulation of cell proliferation GO:0008284 47 0.023
peptide metabolic process GO:0006518 80 0.023
regulation of synaptic transmission GO:0050804 69 0.023
regulation of secretion by cell GO:1903530 39 0.023
cellular response to external stimulus GO:0071496 66 0.023
divalent inorganic cation transport GO:0072511 30 0.023
positive regulation of phosphate metabolic process GO:0045937 139 0.022
stem cell differentiation GO:0048863 117 0.022
lipid homeostasis GO:0055088 33 0.022
cognition GO:0050890 141 0.022
neurotransmitter transport GO:0006836 37 0.022
response to lipopolysaccharide GO:0032496 4 0.022
negative regulation of cell death GO:0060548 81 0.022
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.022
heart process GO:0003015 37 0.022
purine nucleotide catabolic process GO:0006195 109 0.022
response to salt stress GO:0009651 11 0.022
positive regulation of transport GO:0051050 92 0.022
actin cytoskeleton organization GO:0030036 206 0.022
synaptic vesicle localization GO:0097479 53 0.022
regulation of cellular response to stress GO:0080135 89 0.022
chemical homeostasis GO:0048878 92 0.022
carbohydrate derivative metabolic process GO:1901135 217 0.021
gland morphogenesis GO:0022612 145 0.021
regulation of apoptotic process GO:0042981 130 0.021
immune response activating signal transduction GO:0002757 2 0.021
tissue death GO:0016271 102 0.021
nucleoside phosphate metabolic process GO:0006753 162 0.021
regulation of protein catabolic process GO:0042176 55 0.021
calcium ion transport GO:0006816 24 0.021
growth GO:0040007 359 0.021
negative regulation of apoptotic process GO:0043066 63 0.021
salivary gland morphogenesis GO:0007435 145 0.021
regionalization GO:0003002 416 0.021
epithelium migration GO:0090132 148 0.020
protein processing GO:0016485 68 0.020
embryonic organ development GO:0048568 50 0.020
negative regulation of intracellular signal transduction GO:1902532 57 0.020
negative regulation of nucleic acid templated transcription GO:1903507 240 0.020
organic cyclic compound catabolic process GO:1901361 168 0.020
peripheral nervous system development GO:0007422 52 0.020
positive regulation of protein phosphorylation GO:0001934 34 0.020
cellular nitrogen compound catabolic process GO:0044270 165 0.020
neuromuscular junction development GO:0007528 149 0.019
purine ribonucleotide metabolic process GO:0009150 145 0.019
positive regulation of kinase activity GO:0033674 25 0.019
positive regulation of rna biosynthetic process GO:1902680 266 0.019
regulation of cell morphogenesis GO:0022604 163 0.019
organelle localization GO:0051640 148 0.019
negative regulation of gene expression GO:0010629 387 0.019
cellular lipid metabolic process GO:0044255 83 0.019
organic hydroxy compound catabolic process GO:1901616 4 0.019
regulation of cellular catabolic process GO:0031329 157 0.019
negative regulation of nervous system development GO:0051961 92 0.019
protein phosphorylation GO:0006468 169 0.019
regulation of protein phosphorylation GO:0001932 64 0.019
paracrine signaling GO:0038001 7 0.019
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.018
nucleobase containing small molecule metabolic process GO:0055086 174 0.018
dna metabolic process GO:0006259 227 0.018
signal transduction by phosphorylation GO:0023014 107 0.018
carbohydrate biosynthetic process GO:0016051 17 0.018
positive regulation of gene expression GO:0010628 290 0.018
dna damage checkpoint GO:0000077 78 0.018
cell junction assembly GO:0034329 42 0.018
positive regulation of phosphorylation GO:0042327 87 0.018
negative regulation of catalytic activity GO:0043086 42 0.018
immune response regulating signaling pathway GO:0002764 2 0.017
dna integrity checkpoint GO:0031570 81 0.017
cellular protein catabolic process GO:0044257 83 0.017
regulation of catalytic activity GO:0050790 185 0.017
regulation of immune response GO:0050776 118 0.017
regulation of dna metabolic process GO:0051052 34 0.017
single organism biosynthetic process GO:0044711 206 0.017
positive regulation of neuron projection development GO:0010976 14 0.017
substrate adhesion dependent cell spreading GO:0034446 2 0.017
negative regulation of protein modification process GO:0031400 29 0.017
jnk cascade GO:0007254 50 0.017
membrane depolarization GO:0051899 4 0.017
dorsal ventral pattern formation GO:0009953 133 0.017
regulation of organelle organization GO:0033043 196 0.017
cellular component disassembly GO:0022411 46 0.017
response to oxygen levels GO:0070482 59 0.016
regulation of neurotransmitter levels GO:0001505 38 0.016
intracellular transport GO:0046907 228 0.016
response to virus GO:0009615 28 0.016
ribonucleotide metabolic process GO:0009259 145 0.016
embryonic ectodermal digestive tract development GO:0048611 4 0.016
response to oxygen radical GO:0000305 3 0.016
positive regulation of proteolysis GO:0045862 52 0.016
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.016
energy derivation by oxidation of organic compounds GO:0015980 32 0.016
regulation of defense response GO:0031347 102 0.016
defense response to other organism GO:0098542 225 0.016
cellular response to nutrient levels GO:0031669 62 0.016
notch signaling pathway GO:0007219 120 0.016
purine nucleoside metabolic process GO:0042278 127 0.016
rna processing GO:0006396 147 0.016
cation transport GO:0006812 110 0.016
epidermis development GO:0008544 65 0.016
negative regulation of biosynthetic process GO:0009890 277 0.015
cell redox homeostasis GO:0045454 5 0.015
release of sequestered calcium ion into cytosol GO:0051209 1 0.015
regulation of phosphorus metabolic process GO:0051174 210 0.015
cell growth GO:0016049 108 0.015
syncytium formation by plasma membrane fusion GO:0000768 43 0.015
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 24 0.015
glycosyl compound catabolic process GO:1901658 112 0.015
positive regulation of mapk cascade GO:0043410 63 0.015
tissue migration GO:0090130 155 0.015
Fly
cellular response to oxygen containing compound GO:1901701 79 0.015
chitin based cuticle sclerotization GO:0007593 19 0.015
response to temperature stimulus GO:0009266 106 0.015
secretion by cell GO:0032940 101 0.015
regulation of dendrite development GO:0050773 37 0.015
stress activated mapk cascade GO:0051403 52 0.015
collateral sprouting GO:0048668 3 0.015
activation of protein kinase activity GO:0032147 12 0.014
skin development GO:0043588 65 0.014
response to external biotic stimulus GO:0043207 293 0.014
intrinsic apoptotic signaling pathway GO:0097193 16 0.014
blastoderm segmentation GO:0007350 159 0.014
lateral inhibition GO:0046331 206 0.014
g protein coupled receptor signaling pathway GO:0007186 136 0.014
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.014
negative regulation of kinase activity GO:0033673 16 0.014
developmental programmed cell death GO:0010623 138 0.014
positive regulation of protein modification process GO:0031401 58 0.014
retina development in camera type eye GO:0060041 4 0.014
response to bacterium GO:0009617 198 0.014
protein transport GO:0015031 155 0.014
gastrulation GO:0007369 70 0.014
Fly
behavioral response to ethanol GO:0048149 49 0.014
organ or tissue specific immune response GO:0002251 10 0.014
rna localization GO:0006403 115 0.014
exocrine system development GO:0035272 162 0.014
nucleoside metabolic process GO:0009116 127 0.014
cellular response to extracellular stimulus GO:0031668 64 0.014
ion transport GO:0006811 145 0.014
actin filament organization GO:0007015 126 0.014
eye morphogenesis GO:0048592 260 0.014
mesenchymal cell differentiation GO:0048762 1 0.014
genital disc development GO:0035215 44 0.013
semaphorin plexin signaling pathway GO:0071526 4 0.013
positive regulation of protein kinase activity GO:0045860 25 0.013
establishment of vesicle localization GO:0051650 51 0.013
response to hypoxia GO:0001666 53 0.013
ribonucleoside catabolic process GO:0042454 112 0.013
nucleotide metabolic process GO:0009117 161 0.013
regulation of cell cycle GO:0051726 291 0.013
male gamete generation GO:0048232 201 0.013
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.013
cell cell signaling involved in cell fate commitment GO:0045168 210 0.013
cellular macromolecular complex assembly GO:0034622 153 0.013
regulation of endocytosis GO:0030100 37 0.013
ribonucleoside metabolic process GO:0009119 127 0.013
modification dependent macromolecule catabolic process GO:0043632 79 0.013
organophosphate catabolic process GO:0046434 112 0.013
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.013
regulation of cell motility GO:2000145 23 0.013
salivary gland cell autophagic cell death GO:0035071 83 0.013
cellular response to hormone stimulus GO:0032870 44 0.013
cellular component assembly involved in morphogenesis GO:0010927 151 0.013
limb morphogenesis GO:0035108 1 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.013
cellular response to reactive oxygen species GO:0034614 14 0.012
protein complex disassembly GO:0043241 36 0.012
cell cell junction organization GO:0045216 55 0.012
macromolecular complex disassembly GO:0032984 37 0.012
organophosphate biosynthetic process GO:0090407 46 0.012
dendrite morphogenesis GO:0048813 199 0.012
negative regulation of cell proliferation GO:0008285 69 0.012
cell recognition GO:0008037 102 0.012
intracellular protein transport GO:0006886 104 0.012
cell cycle arrest GO:0007050 4 0.012
regulation of protein localization GO:0032880 76 0.012
taxis GO:0042330 304 0.012
defense response to gram negative bacterium GO:0050829 94 0.012
regulation of intracellular transport GO:0032386 64 0.012
regulation of cellular protein catabolic process GO:1903362 44 0.012
cellular homeostasis GO:0019725 80 0.012
generation of precursor metabolites and energy GO:0006091 42 0.012
stress activated protein kinase signaling cascade GO:0031098 55 0.012
positive regulation of hydrolase activity GO:0051345 78 0.012
nuclear division GO:0000280 332 0.012
response to nitrogen compound GO:1901698 90 0.012
response to decreased oxygen levels GO:0036293 58 0.012
positive regulation of rna metabolic process GO:0051254 271 0.012
sensory perception GO:0007600 196 0.012
positive regulation of protein transport GO:0051222 37 0.012
autophagic cell death GO:0048102 83 0.012
hindbrain development GO:0030902 2 0.012
epithelial cell morphogenesis GO:0003382 25 0.012
molting cycle chitin based cuticle GO:0007591 56 0.011

mth disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.037
disease of metabolism DOID:0014667 0 0.028
musculoskeletal system disease DOID:17 0 0.027
connective tissue disease DOID:65 0 0.014