Drosophila melanogaster

303 known processes

gig (Dmel_CG6975)

gigas

(Aliases: dTSC2,6975,dTsc2,Tsc2,Tsc2/gig,CG6975,ME 109,Dmel\CG6975,C1,l(3)109,TSC2,tsc2)

gig biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular response to starvation GO:0009267 61 0.982
stem cell maintenance GO:0019827 67 0.981
regulation of cell differentiation GO:0045595 302 0.965
regulation of developmental growth GO:0048638 174 0.965
autophagy GO:0006914 108 0.961
establishment of localization in cell GO:0051649 402 0.958
Mouse
regulation of cellular component biogenesis GO:0044087 201 0.935
learning or memory GO:0007611 141 0.934
response to starvation GO:0042594 97 0.934
negative regulation of response to stimulus GO:0048585 258 0.922
regulation of growth GO:0040008 233 0.916
cellular protein modification process GO:0006464 438 0.906
negative regulation of nervous system development GO:0051961 92 0.897
growth GO:0040007 359 0.893
cellular response to extracellular stimulus GO:0031668 64 0.885
regulation of autophagy GO:0010506 62 0.878
negative regulation of signaling GO:0023057 219 0.878
regulation of multicellular organismal development GO:2000026 414 0.876
negative regulation of cellular component organization GO:0051129 108 0.864
regulation of cellular catabolic process GO:0031329 157 0.863
cellular catabolic process GO:0044248 372 0.856
regulation of apoptotic process GO:0042981 130 0.850
autophagic vacuole assembly GO:0000045 2 0.836
axonogenesis GO:0007409 290 0.826
catabolic process GO:0009056 409 0.822
regulation of nervous system development GO:0051960 248 0.819
compound eye photoreceptor development GO:0042051 78 0.809
negative regulation of signal transduction GO:0009968 206 0.808
single organism behavior GO:0044708 391 0.808
protein localization GO:0008104 284 0.806
Mouse Rat
negative regulation of developmental growth GO:0048640 64 0.770
multi organism behavior GO:0051705 175 0.767
apoptotic process GO:0006915 159 0.764
response to extracellular stimulus GO:0009991 116 0.763
oocyte development GO:0048599 124 0.755
negative regulation of cell communication GO:0010648 223 0.751
regulation of programmed cell death GO:0043067 152 0.749
cell death GO:0008219 279 0.741
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.725
Mouse
macromolecular complex assembly GO:0065003 256 0.721
Rat
protein modification process GO:0036211 438 0.713
oocyte differentiation GO:0009994 145 0.712
regulation of multicellular organism growth GO:0040014 40 0.694
cellular response to nutrient levels GO:0031669 62 0.687
regulation of catabolic process GO:0009894 170 0.687
axon development GO:0061564 297 0.686
cell division GO:0051301 248 0.685
heart development GO:0007507 82 0.683
Mouse
meiotic nuclear division GO:0007126 151 0.676
larval midgut histolysis GO:0035069 22 0.674
negative regulation of developmental process GO:0051093 201 0.665
regulation of cell development GO:0060284 215 0.656
cell cycle phase transition GO:0044770 140 0.650
regulation of multi organism process GO:0043900 131 0.645
single organism cellular localization GO:1902580 180 0.643
Mouse
response to oxygen containing compound GO:1901700 200 0.633
nuclear division GO:0000280 332 0.629
positive regulation of multicellular organism growth GO:0040018 21 0.624
cell cell signaling involved in cell fate commitment GO:0045168 210 0.622
dna metabolic process GO:0006259 227 0.608
positive regulation of macromolecule metabolic process GO:0010604 405 0.606
eye development GO:0001654 323 0.600
regulation of cell death GO:0010941 173 0.599
protein transport GO:0015031 155 0.598
Mouse
vesicle localization GO:0051648 55 0.594
multicellular organism growth GO:0035264 46 0.588
response to organonitrogen compound GO:0010243 75 0.565
cell proliferation GO:0008283 299 0.551
eye photoreceptor cell development GO:0042462 81 0.549
wnt signaling pathway GO:0016055 98 0.547
Rat
protein complex biogenesis GO:0070271 201 0.546
Rat
positive regulation of developmental process GO:0051094 143 0.542
positive regulation of protein metabolic process GO:0051247 128 0.533
meiotic cell cycle GO:0051321 171 0.529
developmental growth GO:0048589 280 0.517
enzyme linked receptor protein signaling pathway GO:0007167 179 0.511
epithelial cell development GO:0002064 274 0.507
single organism catabolic process GO:0044712 228 0.507
ovarian follicle cell development GO:0030707 248 0.502
determination of adult lifespan GO:0008340 137 0.501
negative regulation of cell differentiation GO:0045596 143 0.500
synapse organization GO:0050808 196 0.482
phosphorylation GO:0016310 294 0.474
macroautophagy GO:0016236 42 0.461
germarium derived egg chamber formation GO:0007293 101 0.454
single organism intracellular transport GO:1902582 207 0.454
Mouse
cellular protein localization GO:0034613 160 0.441
Mouse
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.437
eye morphogenesis GO:0048592 260 0.433
axon guidance GO:0007411 233 0.431
regulation of cellular component size GO:0032535 98 0.428
regulation of protein complex assembly GO:0043254 42 0.423
protein modification by small protein conjugation or removal GO:0070647 106 0.421
organelle fission GO:0048285 340 0.417
intracellular transport GO:0046907 228 0.402
Mouse
compound eye development GO:0048749 307 0.401
programmed cell death GO:0012501 257 0.393
regulation of response to stress GO:0080134 200 0.388
actin filament polymerization GO:0030041 27 0.385
regulation of cell size GO:0008361 63 0.380
rna localization GO:0006403 115 0.380
regionalization GO:0003002 416 0.379
establishment of organelle localization GO:0051656 122 0.377
regulation of glial cell proliferation GO:0060251 11 0.377
positive regulation of cell death GO:0010942 69 0.365
blastoderm segmentation GO:0007350 159 0.364
proteolysis GO:0006508 192 0.362
cellular response to chemical stimulus GO:0070887 199 0.361
stem cell differentiation GO:0048863 117 0.358
intracellular signal transduction GO:0035556 300 0.354
negative regulation of cellular metabolic process GO:0031324 382 0.353
Mouse Rat
lateral inhibition GO:0046331 206 0.351
cellular macromolecular complex assembly GO:0034622 153 0.349
g1 s transition of mitotic cell cycle GO:0000082 31 0.349
learning GO:0007612 75 0.331
regulation of organ growth GO:0046620 42 0.328
negative regulation of neurogenesis GO:0050768 53 0.324
eye photoreceptor cell differentiation GO:0001754 145 0.314
neuron projection guidance GO:0097485 241 0.313
negative regulation of multicellular organismal process GO:0051241 142 0.312
regulation of anatomical structure size GO:0090066 163 0.310
brain development GO:0007420 120 0.309
death GO:0016265 284 0.309
columnar cuboidal epithelial cell development GO:0002066 249 0.307
taxis GO:0042330 304 0.305
Mouse
protein localization to plasma membrane GO:0072659 13 0.301
Mouse
digestive system development GO:0055123 149 0.298
positive regulation of cellular component organization GO:0051130 156 0.294
organic substance catabolic process GO:1901575 308 0.291
nucleoside triphosphate catabolic process GO:0009143 108 0.286
actin cytoskeleton organization GO:0030036 206 0.285
actin filament based process GO:0030029 220 0.285
protein modification by small protein conjugation GO:0032446 79 0.281
germarium derived female germ line cyst formation GO:0030727 42 0.280
protein ubiquitination GO:0016567 70 0.279
positive regulation of cell communication GO:0010647 250 0.279
positive regulation of phosphate metabolic process GO:0045937 139 0.278
protein catabolic process GO:0030163 101 0.276
compound eye morphogenesis GO:0001745 249 0.275
chemotaxis GO:0006935 249 0.275
Mouse
regulation of anatomical structure morphogenesis GO:0022603 242 0.274
mitotic cell cycle phase transition GO:0044772 138 0.273
embryonic pattern specification GO:0009880 174 0.270
positive regulation of signaling GO:0023056 243 0.268
nucleotide catabolic process GO:0009166 109 0.267
female germ line cyst formation GO:0048135 42 0.267
hindbrain development GO:0030902 2 0.264
response to nitrogen compound GO:1901698 90 0.262
digestive tract development GO:0048565 149 0.259
positive regulation of multicellular organismal process GO:0051240 143 0.258
macromolecule catabolic process GO:0009057 161 0.257
establishment of vesicle localization GO:0051650 51 0.248
regulation of cell proliferation GO:0042127 163 0.243
negative regulation of programmed cell death GO:0043069 72 0.240
positive regulation of signal transduction GO:0009967 223 0.240
aging GO:0007568 143 0.238
regulation of neuron differentiation GO:0045664 103 0.237
stem cell development GO:0048864 79 0.235
regulation of cellular response to insulin stimulus GO:1900076 17 0.231
regulation of response to external stimulus GO:0032101 115 0.228
purine nucleoside metabolic process GO:0042278 127 0.226
mapk cascade GO:0000165 107 0.225
Rat
regulation of neurogenesis GO:0050767 158 0.224
regulation of phosphorus metabolic process GO:0051174 210 0.223
locomotory behavior GO:0007626 176 0.221
positive regulation of cellular biosynthetic process GO:0031328 316 0.217
Mouse
meiotic cell cycle process GO:1903046 132 0.217
regulation of small gtpase mediated signal transduction GO:0051056 93 0.217
regulation of phosphorylation GO:0042325 147 0.216
germarium derived oocyte fate determination GO:0007294 26 0.216
regulation of actin filament polymerization GO:0030833 25 0.215
regulation of cell cycle phase transition GO:1901987 130 0.207
regulation of cellular protein metabolic process GO:0032268 243 0.207
reproductive behavior GO:0019098 122 0.200
regulation of cell cycle GO:0051726 291 0.197
actin polymerization or depolymerization GO:0008154 31 0.195
stem cell division GO:0017145 69 0.195
response to oxidative stress GO:0006979 86 0.195
regulation of phosphate metabolic process GO:0019220 210 0.194
neuromuscular junction development GO:0007528 149 0.192
cellular response to endogenous stimulus GO:0071495 80 0.189
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.188
transcription from rna polymerase ii promoter GO:0006366 368 0.188
Mouse
cognition GO:0050890 141 0.186
tube morphogenesis GO:0035239 191 0.186
Mouse
oocyte microtubule cytoskeleton organization GO:0016325 35 0.185
regulation of synapse organization GO:0050807 110 0.183
rna transport GO:0050658 46 0.182
epithelial cell migration GO:0010631 148 0.181
regulation of imaginal disc growth GO:0045570 26 0.180
positive regulation of programmed cell death GO:0043068 62 0.180
positive regulation of cellular component biogenesis GO:0044089 80 0.177
regulation of dendrite morphogenesis GO:0048814 28 0.174
cell cycle g1 s phase transition GO:0044843 31 0.174
ribonucleoside metabolic process GO:0009119 127 0.169
regulation of protein transport GO:0051223 57 0.165
regulation of organelle organization GO:0033043 196 0.162
protein complex assembly GO:0006461 200 0.161
Rat
cardiovascular system development GO:0072358 82 0.159
Mouse
protein phosphorylation GO:0006468 169 0.158
guanosine containing compound catabolic process GO:1901069 74 0.155
regulation of actin filament length GO:0030832 27 0.154
peptidyl threonine phosphorylation GO:0018107 2 0.154
organic substance transport GO:0071702 257 0.154
Mouse
tube development GO:0035295 244 0.151
Mouse
cellular response to peptide GO:1901653 28 0.149
larval development GO:0002164 104 0.149
regulation of cell cycle process GO:0010564 181 0.148
neuron death GO:0070997 27 0.147
positive regulation of growth GO:0045927 75 0.144
forebrain development GO:0030900 2 0.143
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.142
Mouse
cell motility GO:0048870 251 0.142
negative regulation of cell cycle GO:0045786 116 0.142
regulation of intracellular signal transduction GO:1902531 236 0.140
positive regulation of apoptotic process GO:0043065 47 0.140
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.140
purine ribonucleoside metabolic process GO:0046128 127 0.138
cellular response to external stimulus GO:0071496 66 0.134
positive regulation of molecular function GO:0044093 136 0.133
positive regulation of nucleoside metabolic process GO:0045979 47 0.133
cellular protein complex assembly GO:0043623 71 0.132
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.132
small gtpase mediated signal transduction GO:0007264 88 0.130
regulation of intracellular transport GO:0032386 64 0.128
regulation of cellular localization GO:0060341 136 0.125
positive regulation of biosynthetic process GO:0009891 316 0.124
Mouse
establishment of protein localization GO:0045184 163 0.122
Mouse Rat
regulation of synapse structure and activity GO:0050803 128 0.122
regulation of transport GO:0051049 181 0.122
Mouse
cellular macromolecule localization GO:0070727 220 0.121
Mouse
negative regulation of growth GO:0045926 84 0.120
rho protein signal transduction GO:0007266 14 0.120
synapse assembly GO:0007416 143 0.119
oocyte construction GO:0007308 112 0.119
cytoplasmic transport GO:0016482 130 0.117
Mouse
amine metabolic process GO:0009308 12 0.117
cellular response to hormone stimulus GO:0032870 44 0.116
spindle organization GO:0007051 253 0.116
cellular response to peptide hormone stimulus GO:0071375 28 0.115
organonitrogen compound metabolic process GO:1901564 318 0.114
cellular protein catabolic process GO:0044257 83 0.114
response to endogenous stimulus GO:0009719 119 0.113
apoptotic signaling pathway GO:0097190 27 0.113
negative regulation of apoptotic signaling pathway GO:2001234 5 0.110
negative regulation of synaptic growth at neuromuscular junction GO:0045886 39 0.110
organelle assembly GO:0070925 198 0.109
head development GO:0060322 135 0.109
sensory organ morphogenesis GO:0090596 260 0.109
response to hydrogen peroxide GO:0042542 11 0.108
response to nutrient levels GO:0031667 114 0.107
multi organism reproductive behavior GO:0044705 121 0.106
regulation of protein kinase activity GO:0045859 51 0.105
Mouse Rat
spermatid development GO:0007286 98 0.104
positive regulation of response to stimulus GO:0048584 323 0.104
regulation of establishment of protein localization GO:0070201 61 0.100
carbohydrate derivative catabolic process GO:1901136 118 0.098
germ line stem cell division GO:0042078 25 0.096
negative regulation of mitotic cell cycle GO:0045930 109 0.095
regulation of r7 cell differentiation GO:0045676 15 0.093
purine ribonucleotide metabolic process GO:0009150 145 0.092
regulation of mapk cascade GO:0043408 92 0.092
Rat
immune system process GO:0002376 347 0.092
single organism nuclear import GO:1902593 51 0.092
Mouse
cellularization GO:0007349 90 0.091
endomembrane system organization GO:0010256 119 0.090
Mouse
regulation of apoptotic signaling pathway GO:2001233 10 0.089
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.089
embryo development ending in birth or egg hatching GO:0009792 152 0.088
Mouse
response to organic cyclic compound GO:0014070 89 0.088
regulation of cellular amine metabolic process GO:0033238 3 0.087
dendrite development GO:0016358 204 0.087
eggshell formation GO:0030703 105 0.086
regulation of localization GO:0032879 275 0.085
Mouse
regulation of secretion GO:0051046 44 0.085
positive regulation of wnt signaling pathway GO:0030177 25 0.085
response to organic substance GO:0010033 284 0.084
regulation of cytoplasmic transport GO:1903649 47 0.084
cell growth GO:0016049 108 0.084
purine containing compound catabolic process GO:0072523 112 0.083
body morphogenesis GO:0010171 2 0.083
actin filament organization GO:0007015 126 0.083
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.083
regulation of mitotic cell cycle GO:0007346 190 0.082
epithelial cell differentiation GO:0030855 322 0.082
protein targeting GO:0006605 64 0.082
Mouse
cellular response to oxygen containing compound GO:1901701 79 0.081
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.081
heterocycle catabolic process GO:0046700 166 0.081
negative regulation of insulin receptor signaling pathway GO:0046627 11 0.079
regulation of wnt signaling pathway GO:0030111 68 0.079
Rat
positive regulation of phosphorus metabolic process GO:0010562 139 0.078
regulation of protein localization GO:0032880 76 0.078
ovarian follicle cell migration GO:0007297 121 0.078
meiotic spindle organization GO:0000212 36 0.077
regulation of protein metabolic process GO:0051246 256 0.077
regulation of neuron projection development GO:0010975 69 0.076
positive regulation of cellular protein metabolic process GO:0032270 118 0.075
regulation of organ morphogenesis GO:2000027 78 0.074
nucleobase containing compound transport GO:0015931 56 0.073
positive regulation of catabolic process GO:0009896 105 0.072
peptidyl amino acid modification GO:0018193 105 0.072
secretion by cell GO:0032940 101 0.071
dendrite morphogenesis GO:0048813 199 0.071
negative regulation of cell cycle phase transition GO:1901988 103 0.071
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.071
localization of cell GO:0051674 257 0.070
regulation of mitotic cell cycle phase transition GO:1901990 130 0.070
negative regulation of cell cycle process GO:0010948 109 0.069
cell type specific apoptotic process GO:0097285 38 0.069
organ growth GO:0035265 56 0.068
positive regulation of developmental growth GO:0048639 62 0.068
cytoplasm organization GO:0007028 64 0.068
regulation of protein ubiquitination GO:0031396 22 0.068
regulation of actin polymerization or depolymerization GO:0008064 27 0.068
insulin receptor signaling pathway GO:0008286 25 0.067
hemopoiesis GO:0030097 46 0.067
cellular macromolecule catabolic process GO:0044265 136 0.066
purine nucleoside triphosphate metabolic process GO:0009144 119 0.066
regulation of cellular amino acid metabolic process GO:0006521 0 0.066
positive regulation of transport GO:0051050 92 0.066
regulation of cellular response to stress GO:0080135 89 0.065
ribose phosphate metabolic process GO:0019693 145 0.065
olfactory behavior GO:0042048 97 0.064
segmentation GO:0035282 207 0.064
oxoacid metabolic process GO:0043436 103 0.062
positive regulation of cell development GO:0010720 61 0.062
negative regulation of cellular protein metabolic process GO:0032269 85 0.062
Mouse Rat
regulation of gtpase activity GO:0043087 44 0.061
photoreceptor cell differentiation GO:0046530 170 0.061
intracellular protein transport GO:0006886 104 0.061
Mouse
vacuolar transport GO:0007034 13 0.060
synaptic growth at neuromuscular junction GO:0051124 119 0.060
negative regulation of cell death GO:0060548 81 0.060
male gamete generation GO:0048232 201 0.059
signal transduction by phosphorylation GO:0023014 107 0.059
Rat
carbohydrate derivative metabolic process GO:1901135 217 0.059
organelle localization GO:0051640 148 0.058
regulation of erk1 and erk2 cascade GO:0070372 39 0.056
purine nucleoside catabolic process GO:0006152 112 0.056
positive regulation of cell differentiation GO:0045597 64 0.056
regulation of synapse assembly GO:0051963 94 0.056
negative regulation of phosphate metabolic process GO:0045936 45 0.056
Mouse Rat
positive regulation of cellular amine metabolic process GO:0033240 0 0.056
cellular response to dna damage stimulus GO:0006974 223 0.055
muscle cell differentiation GO:0042692 103 0.055
larval midgut cell programmed cell death GO:0035096 19 0.054
somatic stem cell maintenance GO:0035019 14 0.054
multicellular organismal reproductive behavior GO:0033057 110 0.054
negative regulation of autophagy GO:0010507 16 0.053
negative regulation of apoptotic process GO:0043066 63 0.053
purine ribonucleoside catabolic process GO:0046130 112 0.053
positive regulation of protein phosphorylation GO:0001934 34 0.053
establishment of synaptic vesicle localization GO:0097480 50 0.053
regulation of cytoskeleton organization GO:0051493 89 0.052
nitrogen compound transport GO:0071705 85 0.052
response to acid chemical GO:0001101 25 0.052
positive regulation of autophagy GO:0010508 21 0.052
regulation of proteolysis GO:0030162 87 0.052
germ line stem cell maintenance GO:0030718 50 0.051
negative regulation of phosphorus metabolic process GO:0010563 45 0.051
Mouse Rat
membrane organization GO:0061024 112 0.051
Mouse
negative regulation of organ growth GO:0046621 15 0.051
positive regulation of gliogenesis GO:0014015 5 0.051
axis specification GO:0009798 167 0.050
proteasomal protein catabolic process GO:0010498 59 0.049
response to insulin GO:0032868 29 0.047
meiotic chromosome segregation GO:0045132 59 0.047
regulation of system process GO:0044057 36 0.047
lipid modification GO:0030258 24 0.047
negative regulation of cell development GO:0010721 62 0.047
gtp metabolic process GO:0046039 72 0.046
establishment of rna localization GO:0051236 47 0.046
imaginal disc derived wing morphogenesis GO:0007476 337 0.046
ribonucleoside triphosphate catabolic process GO:0009203 108 0.046
kidney development GO:0001822 3 0.046
ribonucleotide metabolic process GO:0009259 145 0.046
cellular lipid metabolic process GO:0044255 83 0.045
developmental maturation GO:0021700 172 0.045
response to peptide hormone GO:0043434 29 0.045
meiosis i GO:0007127 59 0.045
ras protein signal transduction GO:0007265 88 0.045
central nervous system development GO:0007417 201 0.045
regulation of ras protein signal transduction GO:0046578 93 0.045
carboxylic acid metabolic process GO:0019752 92 0.044
multi multicellular organism process GO:0044706 123 0.044
nuclear import GO:0051170 51 0.044
Mouse
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.043
multicellular organismal aging GO:0010259 140 0.043
cellular response to nitrogen compound GO:1901699 51 0.042
posttranscriptional regulation of gene expression GO:0010608 145 0.042
secretion GO:0046903 109 0.042
nucleobase containing small molecule metabolic process GO:0055086 174 0.041
kidney epithelium development GO:0072073 3 0.041
regulation of necrotic cell death GO:0010939 1 0.041
pre mirna processing GO:0031054 3 0.041
protein localization to organelle GO:0033365 82 0.040
Mouse
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.040
synaptic vesicle localization GO:0097479 53 0.040
molting cycle GO:0042303 56 0.040
nucleoside triphosphate metabolic process GO:0009141 120 0.039
regulation of cell morphogenesis GO:0022604 163 0.039
divalent inorganic cation homeostasis GO:0072507 29 0.039
regulation of gtp catabolic process GO:0033124 44 0.038
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.038
photoreceptor cell development GO:0042461 96 0.038
response to peptide GO:1901652 29 0.038
negative regulation of notch signaling pathway GO:0045746 41 0.037
response to alcohol GO:0097305 95 0.037
regulation of protein modification by small protein conjugation or removal GO:1903320 25 0.036
modification dependent protein catabolic process GO:0019941 78 0.036
wing disc morphogenesis GO:0007472 344 0.036
vesicle organization GO:0016050 44 0.036
positive regulation of mapk cascade GO:0043410 63 0.035
regulation of ras gtpase activity GO:0032318 38 0.035
germ line cyst formation GO:0048134 44 0.035
telencephalon development GO:0021537 2 0.034
erk1 and erk2 cascade GO:0070371 39 0.034
establishment of protein localization to membrane GO:0090150 11 0.034
Mouse
lipid metabolic process GO:0006629 121 0.034
g protein coupled receptor signaling pathway GO:0007186 136 0.034
regulation of actin cytoskeleton organization GO:0032956 42 0.034
regulation of nucleocytoplasmic transport GO:0046822 35 0.034
response to lipid GO:0033993 38 0.034
positive regulation of gtpase activity GO:0043547 43 0.033
spermatogenesis GO:0007283 200 0.033
spindle assembly GO:0051225 80 0.033
regulation of meiosis GO:0040020 3 0.033
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.033
Mouse
ubiquitin dependent protein catabolic process GO:0006511 78 0.033
purine nucleoside triphosphate catabolic process GO:0009146 108 0.033
appendage development GO:0048736 401 0.033
sex differentiation GO:0007548 81 0.033
negative regulation of protein phosphorylation GO:0001933 17 0.032
Mouse Rat
digestive tract morphogenesis GO:0048546 127 0.032
positive regulation of erk1 and erk2 cascade GO:0070374 36 0.032
synaptic transmission GO:0007268 288 0.032
neurological system process GO:0050877 358 0.032
cell migration GO:0016477 238 0.032
oocyte fate determination GO:0030716 27 0.032
endocytosis GO:0006897 310 0.032
positive regulation of intracellular signal transduction GO:1902533 116 0.031
peptidyl threonine modification GO:0018210 3 0.031
synaptic vesicle transport GO:0048489 50 0.031
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.031
positive regulation of gtp catabolic process GO:0033126 43 0.031
tor signaling GO:0031929 32 0.031
positive regulation of establishment of protein localization to plasma membrane GO:0090004 3 0.031
positive regulation of phosphorylation GO:0042327 87 0.031
embryonic morphogenesis GO:0048598 206 0.030
Mouse
plasma membrane organization GO:0007009 26 0.030
Mouse
regulation of protein polymerization GO:0032271 28 0.030
negative regulation of cell size GO:0045792 19 0.030
gastrulation GO:0007369 70 0.030
phosphatidylinositol mediated signaling GO:0048015 4 0.030
Mouse
negative regulation of synapse assembly GO:0051964 39 0.030
oocyte anterior posterior axis specification GO:0007314 72 0.030
anterior posterior pattern specification GO:0009952 136 0.030
hematopoietic or lymphoid organ development GO:0048534 57 0.030
small molecule metabolic process GO:0044281 305 0.030
regulation of nucleoside metabolic process GO:0009118 50 0.029
positive regulation of protein modification process GO:0031401 58 0.029
positive regulation of protein localization to plasma membrane GO:1903078 3 0.029
positive regulation of cellular catabolic process GO:0031331 95 0.029
positive regulation of nucleotide catabolic process GO:0030813 46 0.029
mrna processing GO:0006397 104 0.028
anterior posterior axis specification embryo GO:0008595 103 0.028
regulation of photoreceptor cell differentiation GO:0046532 34 0.028
mitotic g2 m transition checkpoint GO:0044818 70 0.028
inositol lipid mediated signaling GO:0048017 4 0.028
Mouse
regulation of membrane potential GO:0042391 35 0.027
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.027
guanosine containing compound metabolic process GO:1901068 74 0.027
regulation of meiotic cell cycle GO:0051445 9 0.027
nucleoside metabolic process GO:0009116 127 0.026
tissue death GO:0016271 102 0.026
aromatic compound catabolic process GO:0019439 166 0.026
cystoblast division GO:0007282 10 0.026
glycosyl compound catabolic process GO:1901658 112 0.026
regulation of nurse cell apoptotic process GO:0045477 9 0.026
oocyte axis specification GO:0007309 108 0.025
regulation of hydrolase activity GO:0051336 97 0.025
female meiotic division GO:0007143 70 0.025
negative regulation of neuroblast proliferation GO:0007406 27 0.025
response to hexose GO:0009746 3 0.025
eye pigment granule organization GO:0008057 12 0.025
regulation of epithelial cell proliferation GO:0050678 4 0.024
Rat
negative regulation of protein modification process GO:0031400 29 0.024
Mouse Rat
notch signaling pathway GO:0007219 120 0.024
olfactory learning GO:0008355 56 0.024
gliogenesis GO:0042063 80 0.023
regulation of gliogenesis GO:0014013 11 0.023
regulation of purine nucleotide catabolic process GO:0033121 48 0.023

gig disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.119
cancer DOID:162 0 0.087
organ system cancer DOID:0050686 0 0.087
disease of anatomical entity DOID:7 0 0.029
central nervous system disease DOID:331 0 0.024
nervous system disease DOID:863 0 0.024