Drosophila melanogaster

19 known processes

Hml (Dmel_CG7002)

Hemolectin

(Aliases: Dmel\CG7002,hml,CG7002,CT21553,d-hml)

Hml biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
melanotic encapsulation of foreign target GO:0035011 30 0.985
encapsulation of foreign target GO:0035010 38 0.933
melanization defense response GO:0035006 45 0.814
defense response to gram positive bacterium GO:0050830 41 0.753
melanin metabolic process GO:0006582 47 0.750
secondary metabolic process GO:0019748 75 0.611
phenol containing compound metabolic process GO:0018958 57 0.545
axon guidance GO:0007411 233 0.521
motor neuron axon guidance GO:0008045 58 0.502
defense response GO:0006952 300 0.469
pigment metabolic process GO:0042440 84 0.465
defense response to bacterium GO:0042742 178 0.440
response to other organism GO:0051707 293 0.427
imaginal disc derived appendage development GO:0048737 399 0.414
immune effector process GO:0002252 98 0.381
innate immune response GO:0045087 144 0.376
immune response GO:0006955 246 0.348
response to external biotic stimulus GO:0043207 293 0.341
neuron projection guidance GO:0097485 241 0.311
defense response to other organism GO:0098542 225 0.296
defense response to fungus GO:0050832 48 0.293
intracellular protein transmembrane import GO:0044743 4 0.277
lateral inhibition GO:0046331 206 0.273
cell cell signaling involved in cell fate commitment GO:0045168 210 0.271
response to fungus GO:0009620 50 0.259
response to bacterium GO:0009617 198 0.258
immune system process GO:0002376 347 0.251
chemotaxis GO:0006935 249 0.222
organic hydroxy compound metabolic process GO:1901615 83 0.207
transmembrane transport GO:0055085 139 0.197
response to biotic stimulus GO:0009607 294 0.167
axon development GO:0061564 297 0.142
intracellular transport GO:0046907 228 0.131
intracellular protein transmembrane transport GO:0065002 4 0.120
axonogenesis GO:0007409 290 0.113
synaptic target recognition GO:0008039 45 0.113
protein transmembrane transport GO:0071806 4 0.102
cellular macromolecule localization GO:0070727 220 0.093
post embryonic appendage morphogenesis GO:0035120 385 0.092
establishment of localization in cell GO:0051649 402 0.089
cellular catabolic process GO:0044248 372 0.067
storage protein import into fat body GO:0015032 2 0.066
appendage development GO:0048736 401 0.060
neurological system process GO:0050877 358 0.059
cellular protein localization GO:0034613 160 0.056
organic substance transport GO:0071702 257 0.054
taxis GO:0042330 304 0.053
body morphogenesis GO:0010171 2 0.051
single organism intracellular transport GO:1902582 207 0.047
extracellular matrix organization GO:0030198 32 0.046
extracellular structure organization GO:0043062 46 0.043
imaginal disc derived wing morphogenesis GO:0007476 337 0.042
cell recognition GO:0008037 102 0.041
protein localization GO:0008104 284 0.040
imaginal disc derived appendage morphogenesis GO:0035114 395 0.038
carbohydrate derivative metabolic process GO:1901135 217 0.037
spermatogenesis GO:0007283 200 0.036
kidney development GO:0001822 3 0.036
establishment of protein localization GO:0045184 163 0.036
wing disc morphogenesis GO:0007472 344 0.034
macromolecule catabolic process GO:0009057 161 0.034
carbohydrate derivative catabolic process GO:1901136 118 0.034
intracellular protein transport GO:0006886 104 0.033
positive regulation of response to stimulus GO:0048584 323 0.032
cellular protein modification process GO:0006464 438 0.031
catabolic process GO:0009056 409 0.031
organonitrogen compound catabolic process GO:1901565 128 0.031
regulation of response to stress GO:0080134 200 0.031
aminoglycan metabolic process GO:0006022 18 0.031
regionalization GO:0003002 416 0.030
protein import GO:0017038 55 0.029
negative regulation of developmental process GO:0051093 201 0.029
regulation of multicellular organismal development GO:2000026 414 0.028
appendage morphogenesis GO:0035107 397 0.028
imaginal disc derived leg morphogenesis GO:0007480 80 0.028
negative regulation of response to stimulus GO:0048585 258 0.027
compound eye morphogenesis GO:0001745 249 0.026
pattern recognition receptor signaling pathway GO:0002221 2 0.026
cellular amine metabolic process GO:0044106 12 0.025
regulation of cellular response to stress GO:0080135 89 0.025
regulation of immune system process GO:0002682 176 0.024
vesicle mediated transport GO:0016192 381 0.024
single organism behavior GO:0044708 391 0.024
organic cyclic compound catabolic process GO:1901361 168 0.023
immune response regulating signaling pathway GO:0002764 2 0.023
regulation of cell proliferation GO:0042127 163 0.023
glucosamine containing compound catabolic process GO:1901072 3 0.023
regulation of cellular component biogenesis GO:0044087 201 0.023
leg disc development GO:0035218 92 0.023
immune response activating signal transduction GO:0002757 2 0.023
positive regulation of phosphate metabolic process GO:0045937 139 0.023
intracellular signal transduction GO:0035556 300 0.023
regulation of cellular protein metabolic process GO:0032268 243 0.023
ethanolamine containing compound metabolic process GO:0042439 4 0.023
regulation of nervous system development GO:0051960 248 0.023
eye morphogenesis GO:0048592 260 0.022
regulation of cell cycle GO:0051726 291 0.022
negative regulation of multicellular organismal process GO:0051241 142 0.022
synaptic transmission GO:0007268 288 0.022
ribonucleoside catabolic process GO:0042454 112 0.022
cell migration GO:0016477 238 0.021
developmental growth GO:0048589 280 0.021
sensory perception GO:0007600 196 0.021
antimicrobial humoral response GO:0019730 99 0.021
open tracheal system development GO:0007424 204 0.021
organic substance catabolic process GO:1901575 308 0.021
forebrain development GO:0030900 2 0.021
protein modification process GO:0036211 438 0.021
positive regulation of macromolecule metabolic process GO:0010604 405 0.020
actin filament organization GO:0007015 126 0.020
leg disc morphogenesis GO:0007478 80 0.020
organelle fission GO:0048285 340 0.020
proteolysis GO:0006508 192 0.020
regulation of cell differentiation GO:0045595 302 0.020
response to oxidative stress GO:0006979 86 0.019
camera type eye development GO:0043010 4 0.019
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.019
secretion GO:0046903 109 0.019
response to organophosphorus GO:0046683 2 0.019
purine ribonucleoside catabolic process GO:0046130 112 0.019
regulation of molecular function GO:0065009 217 0.019
multicellular organismal aging GO:0010259 140 0.019
neuromuscular junction development GO:0007528 149 0.019
amine metabolic process GO:0009308 12 0.018
organonitrogen compound metabolic process GO:1901564 318 0.018
positive regulation of immune system process GO:0002684 68 0.018
response to lipopolysaccharide GO:0032496 4 0.018
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.018
spermatid differentiation GO:0048515 114 0.018
endocytosis GO:0006897 310 0.018
purine ribonucleotide metabolic process GO:0009150 145 0.018
cell proliferation GO:0008283 299 0.018
neurotransmitter transport GO:0006836 37 0.018
response to abiotic stimulus GO:0009628 341 0.018
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.018
glycosyl compound catabolic process GO:1901658 112 0.017
growth GO:0040007 359 0.017
purine containing compound catabolic process GO:0072523 112 0.017
negative regulation of signal transduction GO:0009968 206 0.017
aromatic compound catabolic process GO:0019439 166 0.017
nucleoside metabolic process GO:0009116 127 0.017
negative regulation of nervous system development GO:0051961 92 0.017
cellular ketone metabolic process GO:0042180 24 0.017
regulation of innate immune response GO:0045088 71 0.017
small gtpase mediated signal transduction GO:0007264 88 0.017
phagocytosis GO:0006909 215 0.017
peptide metabolic process GO:0006518 80 0.017
sensory perception of chemical stimulus GO:0007606 116 0.017
steroid catabolic process GO:0006706 1 0.017
regulation of localization GO:0032879 275 0.017
regulation of response to external stimulus GO:0032101 115 0.017
mitotic nuclear division GO:0007067 213 0.016
purine nucleotide metabolic process GO:0006163 146 0.016
cell motility GO:0048870 251 0.016
nucleotide catabolic process GO:0009166 109 0.016
regulation of phosphorus metabolic process GO:0051174 210 0.016
positive regulation of transcription dna templated GO:0045893 266 0.016
regulation of neurogenesis GO:0050767 158 0.016
nuclear division GO:0000280 332 0.016
regulation of catalytic activity GO:0050790 185 0.016
regulation of phosphate metabolic process GO:0019220 210 0.016
cellular nitrogen compound catabolic process GO:0044270 165 0.016
regulation of intracellular signal transduction GO:1902531 236 0.016
gtp metabolic process GO:0046039 72 0.016
regulation of synapse structure and activity GO:0050803 128 0.016
regulation of developmental growth GO:0048638 174 0.016
actin filament bundle assembly GO:0051017 26 0.016
cellular response to dna damage stimulus GO:0006974 223 0.016
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.015
regulation of phosphorylation GO:0042325 147 0.015
purine ribonucleoside metabolic process GO:0046128 127 0.015
cell division GO:0051301 248 0.015
response to organic substance GO:0010033 284 0.015
drinking behavior GO:0042756 2 0.015
ras protein signal transduction GO:0007265 88 0.015
positive regulation of molecular function GO:0044093 136 0.015
spindle organization GO:0007051 253 0.015
positive regulation of catabolic process GO:0009896 105 0.015
sensory organ morphogenesis GO:0090596 260 0.015
localization of cell GO:0051674 257 0.015
nucleobase containing compound catabolic process GO:0034655 165 0.015
epithelial cell differentiation GO:0030855 322 0.015
male gamete generation GO:0048232 201 0.015
regulation of cellular localization GO:0060341 136 0.015
multi organism reproductive behavior GO:0044705 121 0.015
nucleoside phosphate catabolic process GO:1901292 110 0.015
positive regulation of biosynthetic process GO:0009891 316 0.015
purine nucleotide catabolic process GO:0006195 109 0.015
phosphorylation GO:0016310 294 0.015
actin filament based process GO:0030029 220 0.015
muscle structure development GO:0061061 224 0.015
response to axon injury GO:0048678 12 0.015
negative regulation of cell communication GO:0010648 223 0.015
hair cell differentiation GO:0035315 47 0.014
cell projection assembly GO:0030031 94 0.014
sperm individualization GO:0007291 48 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.014
chitin catabolic process GO:0006032 3 0.014
ribonucleotide metabolic process GO:0009259 145 0.014
regulation of cellular catabolic process GO:0031329 157 0.014
rna processing GO:0006396 147 0.014
regulation of protein metabolic process GO:0051246 256 0.014
negative regulation of signaling GO:0023057 219 0.014
regulation of anatomical structure size GO:0090066 163 0.014
regulation of growth GO:0040008 233 0.014
nephron development GO:0072006 3 0.014
positive regulation of cellular biosynthetic process GO:0031328 316 0.014
monocarboxylic acid transport GO:0015718 3 0.014
purine nucleoside catabolic process GO:0006152 112 0.014
cellular amide metabolic process GO:0043603 80 0.014
sleep GO:0030431 49 0.014
ribose phosphate metabolic process GO:0019693 145 0.014
regulation of cellular ketone metabolic process GO:0010565 3 0.014
xenobiotic catabolic process GO:0042178 1 0.014
ribonucleoside triphosphate metabolic process GO:0009199 119 0.014
regulation of transport GO:0051049 181 0.014
synapse organization GO:0050808 196 0.014
cellular response to lipopolysaccharide GO:0071222 3 0.014
regulation of cellular amine metabolic process GO:0033238 3 0.014
carboxylic acid metabolic process GO:0019752 92 0.014
negative regulation of cellular component organization GO:0051129 108 0.014
telencephalon development GO:0021537 2 0.014
regulation of synaptic transmission GO:0050804 69 0.014
morphogenesis of an epithelium GO:0002009 276 0.014
response to heat GO:0009408 63 0.014
urogenital system development GO:0001655 72 0.014
purine nucleoside triphosphate catabolic process GO:0009146 108 0.014
innate immune response activating signal transduction GO:0002758 2 0.014
ribonucleoside metabolic process GO:0009119 127 0.014
regulation of catabolic process GO:0009894 170 0.013
positive regulation of gene expression GO:0010628 290 0.013
chromosome segregation GO:0007059 157 0.013
regulation of circadian rhythm GO:0042752 49 0.013
ion transport GO:0006811 145 0.013
retina development in camera type eye GO:0060041 4 0.013
triglyceride biosynthetic process GO:0019432 2 0.013
guanosine containing compound metabolic process GO:1901068 74 0.013
response to organonitrogen compound GO:0010243 75 0.013
muscle attachment GO:0016203 36 0.013
columnar cuboidal epithelial cell development GO:0002066 249 0.013
aging GO:0007568 143 0.013
organophosphate metabolic process GO:0019637 195 0.013
protein complex biogenesis GO:0070271 201 0.013
defense response to gram negative bacterium GO:0050829 94 0.013
secondary metabolite biosynthetic process GO:0044550 24 0.013
positive regulation of signaling GO:0023056 243 0.013
tube morphogenesis GO:0035239 191 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.013
macromolecular complex assembly GO:0065003 256 0.013
glycosyl compound metabolic process GO:1901657 127 0.013
purine nucleoside triphosphate metabolic process GO:0009144 119 0.013
cellular response to ethanol GO:0071361 4 0.013
hormone catabolic process GO:0042447 3 0.013
ovarian follicle cell development GO:0030707 248 0.013
activation of innate immune response GO:0002218 4 0.013
locomotory behavior GO:0007626 176 0.013
segmentation GO:0035282 207 0.013
respiratory system development GO:0060541 213 0.013
choline metabolic process GO:0019695 1 0.013
nucleoside triphosphate catabolic process GO:0009143 108 0.013
small molecule metabolic process GO:0044281 305 0.013
positive regulation of developmental process GO:0051094 143 0.013
regulation of cell development GO:0060284 215 0.013
regulation of immune response GO:0050776 118 0.013
negative regulation of cellular metabolic process GO:0031324 382 0.013
renal system development GO:0072001 72 0.013
epithelial cell development GO:0002064 274 0.013
nucleoside catabolic process GO:0009164 112 0.013
regulation of small gtpase mediated signal transduction GO:0051056 93 0.013
protein transport GO:0015031 155 0.012
organelle fusion GO:0048284 46 0.012
cellular response to molecule of bacterial origin GO:0071219 3 0.012
single organism membrane organization GO:0044802 93 0.012
cellular macromolecule catabolic process GO:0044265 136 0.012
purine containing compound metabolic process GO:0072521 155 0.012
regulation of behavior GO:0050795 75 0.012
compound eye development GO:0048749 307 0.012
protein phosphorylation GO:0006468 169 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.012
positive regulation of cell migration GO:0030335 2 0.012
regulation of neuron projection development GO:0010975 69 0.012
peptidoglycan catabolic process GO:0009253 3 0.012
rhythmic behavior GO:0007622 76 0.012
mitotic cytokinesis GO:0000281 50 0.012
nucleus organization GO:0006997 45 0.012
amino sugar catabolic process GO:0046348 3 0.012
purine ribonucleotide catabolic process GO:0009154 109 0.012
benzene containing compound metabolic process GO:0042537 3 0.012
multi multicellular organism process GO:0044706 123 0.012
positive regulation of cellular catabolic process GO:0031331 95 0.012
positive regulation of multicellular organismal process GO:0051240 143 0.012
positive regulation of signal transduction GO:0009967 223 0.012
nucleobase containing small molecule metabolic process GO:0055086 174 0.012
heterocycle catabolic process GO:0046700 166 0.012
ribonucleoside triphosphate catabolic process GO:0009203 108 0.012
peripheral nervous system development GO:0007422 52 0.012
regulation of cell morphogenesis GO:0022604 163 0.012
epithelium migration GO:0090132 148 0.012
spermatid development GO:0007286 98 0.012
amine catabolic process GO:0009310 1 0.012
negative regulation of cell differentiation GO:0045596 143 0.012
signal transduction by phosphorylation GO:0023014 107 0.012
circadian rhythm GO:0007623 105 0.012
hematopoietic progenitor cell differentiation GO:0002244 1 0.012
digestive tract development GO:0048565 149 0.012
regulation of hydrolase activity GO:0051336 97 0.012
central nervous system development GO:0007417 201 0.012
peptidoglycan metabolic process GO:0000270 3 0.012
positive regulation of cell motility GO:2000147 3 0.012
chemosensory behavior GO:0007635 106 0.011
female meiotic division GO:0007143 70 0.011
purine nucleoside metabolic process GO:0042278 127 0.011
mitotic spindle organization GO:0007052 220 0.011
regulation of synapse assembly GO:0051963 94 0.011
organelle localization GO:0051640 148 0.011
nucleoside phosphate metabolic process GO:0006753 162 0.011
wound healing GO:0042060 75 0.011
oxidation reduction process GO:0055114 123 0.011
regulation of mitotic cell cycle GO:0007346 190 0.011
wnt signaling pathway GO:0016055 98 0.011
transcription from rna polymerase ii promoter GO:0006366 368 0.011
acetylcholine catabolic process GO:0006581 1 0.011
cellularization GO:0007349 90 0.011
eye development GO:0001654 323 0.011
secretion by cell GO:0032940 101 0.011
membrane depolarization GO:0051899 4 0.011
regulation of cell cycle process GO:0010564 181 0.011
regulation of purine nucleotide catabolic process GO:0033121 48 0.011
positive regulation of catalytic activity GO:0043085 118 0.011
single organism catabolic process GO:0044712 228 0.011
substrate adhesion dependent cell spreading GO:0034446 2 0.011
regulation of cell substrate adhesion GO:0010810 2 0.011
organic acid metabolic process GO:0006082 103 0.011
cellular response to chemical stimulus GO:0070887 199 0.011
positive regulation of cellular component organization GO:0051130 156 0.011
response to copper ion GO:0046688 4 0.011
regulation of notch signaling pathway GO:0008593 100 0.011
adult locomotory behavior GO:0008344 76 0.011
blastoderm segmentation GO:0007350 159 0.011
rna localization GO:0006403 115 0.010
regulation of cellular amino acid metabolic process GO:0006521 0 0.010
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.010
lipid catabolic process GO:0016042 21 0.010
response to virus GO:0009615 28 0.010
positive regulation of cell communication GO:0010647 250 0.010
ribonucleotide catabolic process GO:0009261 109 0.010
regulation of multi organism process GO:0043900 131 0.010
mapk cascade GO:0000165 107 0.010
digestive system development GO:0055123 149 0.010
imaginal disc derived wing vein specification GO:0007474 48 0.010
mrna metabolic process GO:0016071 124 0.010
response to reactive oxygen species GO:0000302 24 0.010
regulation of secretion by cell GO:1903530 39 0.010
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.010
limb development GO:0060173 1 0.010
response to oxygen containing compound GO:1901700 200 0.010
actin mediated cell contraction GO:0070252 21 0.010
regulation of protein localization GO:0032880 76 0.010
reproductive system development GO:0061458 74 0.010
positive regulation of cellular amine metabolic process GO:0033240 0 0.010
response to wounding GO:0009611 94 0.010
endomembrane system organization GO:0010256 119 0.010
estrogen metabolic process GO:0008210 1 0.010
regulation of organelle organization GO:0033043 196 0.010
heart development GO:0007507 82 0.010
regulation of cell shape GO:0008360 113 0.010
gtp catabolic process GO:0006184 72 0.010
nucleoside triphosphate metabolic process GO:0009141 120 0.010
lipid metabolic process GO:0006629 121 0.010

Hml disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.062
nervous system disease DOID:863 0 0.029
central nervous system disease DOID:331 0 0.016
cardiovascular system disease DOID:1287 0 0.016
disease of metabolism DOID:0014667 0 0.015
inherited metabolic disorder DOID:655 0 0.015
neurodegenerative disease DOID:1289 0 0.014
hair disease DOID:421 0 0.013
integumentary system disease DOID:16 0 0.013
hypotrichosis DOID:4535 0 0.013
sensory system disease DOID:0050155 0 0.012
eye disease DOID:5614 0 0.010
eye and adnexa disease DOID:1492 0 0.010
urinary system disease DOID:18 0 0.010