Drosophila melanogaster

79 known processes

pex2 (Dmel_CG7081)

peroxin 2

(Aliases: CG7081,Dmel\CG7081)

pex2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein targeting to peroxisome GO:0006625 2 1.000
establishment of protein localization to peroxisome GO:0072663 2 0.995
protein import into peroxisome matrix GO:0016558 2 0.995
intracellular protein transmembrane import GO:0044743 4 0.959
peroxisome organization GO:0007031 14 0.958
spermatocyte division GO:0048137 13 0.941
peroxisomal transport GO:0043574 2 0.906
protein localization to peroxisome GO:0072662 2 0.865
male gamete generation GO:0048232 201 0.673
spermatogenesis GO:0007283 200 0.431
single organism intracellular transport GO:1902582 207 0.382
reciprocal dna recombination GO:0035825 19 0.375
protein transport GO:0015031 155 0.373
intracellular transport GO:0046907 228 0.336
establishment of localization in cell GO:0051649 402 0.334
cellular macromolecule localization GO:0070727 220 0.332
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.328
cellular protein localization GO:0034613 160 0.278
protein acylation GO:0043543 42 0.228
negative regulation of biosynthetic process GO:0009890 277 0.228
very long chain fatty acid metabolic process GO:0000038 4 0.226
negative regulation of cellular metabolic process GO:0031324 382 0.226
organic substance transport GO:0071702 257 0.207
oxoacid metabolic process GO:0043436 103 0.205
Mouse
protein targeting GO:0006605 64 0.200
organic acid metabolic process GO:0006082 103 0.196
Mouse
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.185
protein modification process GO:0036211 438 0.181
cellular protein modification process GO:0006464 438 0.175
intracellular protein transport GO:0006886 104 0.166
negative regulation of gene expression GO:0010629 387 0.165
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.163
transmembrane transport GO:0055085 139 0.162
organonitrogen compound metabolic process GO:1901564 318 0.155
meiotic cell cycle process GO:1903046 132 0.154
negative regulation of transcription dna templated GO:0045892 237 0.148
protein modification by small protein conjugation or removal GO:0070647 106 0.141
cytoskeleton dependent cytokinesis GO:0061640 81 0.136
single organism cellular localization GO:1902580 180 0.125
cytoplasmic transport GO:0016482 130 0.121
negative regulation of cellular biosynthetic process GO:0031327 277 0.119
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.116
protein transmembrane transport GO:0071806 4 0.109
embryo development ending in birth or egg hatching GO:0009792 152 0.103
cell division GO:0051301 248 0.101
protein modification by small protein conjugation GO:0032446 79 0.095
cytokinesis GO:0000910 90 0.094
intracellular protein transmembrane transport GO:0065002 4 0.093
organic substance catabolic process GO:1901575 308 0.088
establishment or maintenance of cell polarity GO:0007163 167 0.084
cellular lipid catabolic process GO:0044242 16 0.083
negative regulation of rna metabolic process GO:0051253 251 0.082
negative regulation of nucleic acid templated transcription GO:1903507 240 0.081
lipid metabolic process GO:0006629 121 0.081
Mouse
single organism catabolic process GO:0044712 228 0.078
establishment of protein localization GO:0045184 163 0.073
positive regulation of cellular biosynthetic process GO:0031328 316 0.070
peptidyl amino acid modification GO:0018193 105 0.068
response to organic substance GO:0010033 284 0.065
carboxylic acid metabolic process GO:0019752 92 0.065
Mouse
regulation of multi organism process GO:0043900 131 0.061
negative regulation of rna biosynthetic process GO:1902679 240 0.057
negative regulation of phosphorylation GO:0042326 35 0.056
cellular response to organic substance GO:0071310 132 0.055
organelle fission GO:0048285 340 0.054
meiotic cytokinesis GO:0033206 33 0.053
protein import GO:0017038 55 0.053
protein localization GO:0008104 284 0.052
regulation of cell cycle GO:0051726 291 0.052
cellular response to oxygen containing compound GO:1901701 79 0.052
catabolic process GO:0009056 409 0.052
regulation of meiosis GO:0040020 3 0.051
peptidyl lysine acetylation GO:0018394 39 0.050
response to oxygen containing compound GO:1901700 200 0.050
protein localization to organelle GO:0033365 82 0.049
mitotic cell cycle phase transition GO:0044772 138 0.049
growth GO:0040007 359 0.048
protein acetylation GO:0006473 39 0.048
histone acetylation GO:0016573 38 0.047
programmed cell death GO:0012501 257 0.047
positive regulation of phosphate metabolic process GO:0045937 139 0.047
cellular amino acid metabolic process GO:0006520 61 0.045
regulation of cell cycle process GO:0010564 181 0.044
response to abiotic stimulus GO:0009628 341 0.043
larval development GO:0002164 104 0.042
single organism membrane organization GO:0044802 93 0.042
vesicle mediated transport GO:0016192 381 0.042
protein dna complex subunit organization GO:0071824 86 0.041
organonitrogen compound catabolic process GO:1901565 128 0.041
learning or memory GO:0007611 141 0.040
internal peptidyl lysine acetylation GO:0018393 38 0.040
nucleobase containing compound catabolic process GO:0034655 165 0.039
spermatid differentiation GO:0048515 114 0.039
spindle assembly involved in mitosis GO:0090307 50 0.038
protein ubiquitination GO:0016567 70 0.037
multi organism behavior GO:0051705 175 0.037
regulation of transport GO:0051049 181 0.037
regulation of behavior GO:0050795 75 0.037
very long chain fatty acid catabolic process GO:0042760 2 0.036
gene silencing GO:0016458 138 0.035
multi organism reproductive behavior GO:0044705 121 0.035
regulation of cell cycle phase transition GO:1901987 130 0.035
regulation of synapse structure and activity GO:0050803 128 0.035
homeostatic process GO:0042592 199 0.034
Mouse
cellular lipid metabolic process GO:0044255 83 0.034
cellular catabolic process GO:0044248 372 0.034
sensory perception GO:0007600 196 0.033
regulation of mitotic cell cycle GO:0007346 190 0.033
regulation of response to stress GO:0080134 200 0.033
negative regulation of cell communication GO:0010648 223 0.033
stem cell proliferation GO:0072089 88 0.033
regionalization GO:0003002 416 0.032
cellular response to chemical stimulus GO:0070887 199 0.032
mitotic sister chromatid separation GO:0051306 30 0.030
positive regulation of signaling GO:0023056 243 0.030
regulation of establishment of protein localization GO:0070201 61 0.029
cell cycle phase transition GO:0044770 140 0.029
multi multicellular organism process GO:0044706 123 0.029
cellular amine metabolic process GO:0044106 12 0.029
establishment of protein localization to organelle GO:0072594 62 0.029
regulation of cell division GO:0051302 72 0.029
endomembrane system organization GO:0010256 119 0.028
response to alcohol GO:0097305 95 0.028
developmental growth GO:0048589 280 0.027
cell death GO:0008219 279 0.027
meiotic nuclear division GO:0007126 151 0.026
negative regulation of signal transduction GO:0009968 206 0.026
positive regulation of signal transduction GO:0009967 223 0.026
nuclear division GO:0000280 332 0.025
response to organic cyclic compound GO:0014070 89 0.025
positive regulation of protein secretion GO:0050714 9 0.025
response to temperature stimulus GO:0009266 106 0.025
synaptic transmission GO:0007268 288 0.025
dna metabolic process GO:0006259 227 0.025
cellular response to dna damage stimulus GO:0006974 223 0.025
amine metabolic process GO:0009308 12 0.025
regulation of programmed cell death GO:0043067 152 0.024
regulation of cellular localization GO:0060341 136 0.024
negative regulation of response to stimulus GO:0048585 258 0.023
embryonic axis specification GO:0000578 107 0.023
small molecule metabolic process GO:0044281 305 0.023
Mouse
death GO:0016265 284 0.023
regulation of erk1 and erk2 cascade GO:0070372 39 0.023
regulation of synapse organization GO:0050807 110 0.023
single organism behavior GO:0044708 391 0.023
adult behavior GO:0030534 137 0.023
dorsal ventral pattern formation GO:0009953 133 0.023
actin filament based process GO:0030029 220 0.023
positive regulation of macromolecule metabolic process GO:0010604 405 0.023
imaginal disc pattern formation GO:0007447 91 0.022
positive regulation of molecular function GO:0044093 136 0.022
negative regulation of developmental process GO:0051093 201 0.022
stem cell differentiation GO:0048863 117 0.022
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.021
negative regulation of phosphate metabolic process GO:0045936 45 0.021
regulation of stem cell proliferation GO:0072091 40 0.021
purine ribonucleotide catabolic process GO:0009154 109 0.021
negative regulation of cell cycle GO:0045786 116 0.021
chemosensory behavior GO:0007635 106 0.021
regulation of cytoplasmic transport GO:1903649 47 0.021
ion transport GO:0006811 145 0.021
regulation of nucleoside metabolic process GO:0009118 50 0.020
neural precursor cell proliferation GO:0061351 75 0.020
response to glucose GO:0009749 2 0.020
meiotic cell cycle GO:0051321 171 0.020
regulation of cellular protein metabolic process GO:0032268 243 0.020
negative regulation of signaling GO:0023057 219 0.020
internal protein amino acid acetylation GO:0006475 38 0.020
fatty acid catabolic process GO:0009062 9 0.020
negative regulation of phosphorus metabolic process GO:0010563 45 0.020
nucleobase containing small molecule metabolic process GO:0055086 174 0.020
purine ribonucleoside metabolic process GO:0046128 127 0.019
phosphorylation GO:0016310 294 0.019
regulation of intracellular transport GO:0032386 64 0.019
olfactory behavior GO:0042048 97 0.019
actin cytoskeleton organization GO:0030036 206 0.018
proteolysis GO:0006508 192 0.018
regulation of sequestering of calcium ion GO:0051282 3 0.018
chromatin remodeling GO:0006338 72 0.018
regulation of reproductive process GO:2000241 54 0.018
oocyte development GO:0048599 124 0.018
lipid catabolic process GO:0016042 21 0.018
positive regulation of response to stimulus GO:0048584 323 0.018
positive regulation of phosphorus metabolic process GO:0010562 139 0.018
negative regulation of cell cycle process GO:0010948 109 0.018
regulation of cell differentiation GO:0045595 302 0.018
chemical homeostasis GO:0048878 92 0.017
Mouse
trna modification GO:0006400 2 0.017
response to biotic stimulus GO:0009607 294 0.017
secretion GO:0046903 109 0.017
gene silencing by rna GO:0031047 57 0.017
body morphogenesis GO:0010171 2 0.017
negative regulation of mitotic cell cycle GO:0045930 109 0.017
regulation of cellular ketone metabolic process GO:0010565 3 0.017
anterior posterior axis specification embryo GO:0008595 103 0.017
intracellular signal transduction GO:0035556 300 0.017
small gtpase mediated signal transduction GO:0007264 88 0.017
developmental cell growth GO:0048588 52 0.016
regulation of molecular function GO:0065009 217 0.016
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.016
regulation of protein transport GO:0051223 57 0.016
regulation of intracellular signal transduction GO:1902531 236 0.016
macromolecular complex assembly GO:0065003 256 0.016
endocytosis GO:0006897 310 0.016
positive regulation of nucleic acid templated transcription GO:1903508 266 0.016
secretion by cell GO:0032940 101 0.016
cellular chemical homeostasis GO:0055082 40 0.016
digestive tract development GO:0048565 149 0.015
cell cell signaling involved in cell fate commitment GO:0045168 210 0.015
nucleoside phosphate metabolic process GO:0006753 162 0.015
carbohydrate derivative metabolic process GO:1901135 217 0.015
negative regulation of erk1 and erk2 cascade GO:0070373 3 0.015
sensory perception of pain GO:0019233 4 0.015
chromosome segregation GO:0007059 157 0.015
positive regulation of transport GO:0051050 92 0.015
organophosphate catabolic process GO:0046434 112 0.015
regulation of cellular amine metabolic process GO:0033238 3 0.015
nucleosome organization GO:0034728 59 0.015
regulation of mitotic cell cycle phase transition GO:1901990 130 0.015
actin polymerization or depolymerization GO:0008154 31 0.015
notch signaling pathway GO:0007219 120 0.015
heterocycle catabolic process GO:0046700 166 0.014
negative regulation of homeostatic process GO:0032845 2 0.014
neurological system process GO:0050877 358 0.014
regulation of localization GO:0032879 275 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
maintenance of location GO:0051235 73 0.014
asymmetric stem cell division GO:0098722 49 0.014
vitamin metabolic process GO:0006766 2 0.014
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.014
chromosome separation GO:0051304 42 0.014
regulation of protein localization GO:0032880 76 0.014
cell migration GO:0016477 238 0.014
Mouse
male meiosis cytokinesis GO:0007112 26 0.014
axis specification GO:0009798 167 0.014
regulation of secretion by cell GO:1903530 39 0.014
organelle localization GO:0051640 148 0.014
positive regulation of transcription dna templated GO:0045893 266 0.014
somatic stem cell division GO:0048103 37 0.014
negative regulation of cellular protein metabolic process GO:0032269 85 0.013
membrane organization GO:0061024 112 0.013
synapse assembly GO:0007416 143 0.013
regulation of phosphatase activity GO:0010921 3 0.013
regulation of ion transport GO:0043269 39 0.013
positive regulation of biosynthetic process GO:0009891 316 0.013
purine ribonucleoside catabolic process GO:0046130 112 0.013
negative regulation of cellular component organization GO:0051129 108 0.013
segmentation GO:0035282 207 0.013
regulation of anatomical structure size GO:0090066 163 0.013
oocyte construction GO:0007308 112 0.013
determination of adult lifespan GO:0008340 137 0.013
negative regulation of neural precursor cell proliferation GO:2000178 27 0.013
transcription from rna polymerase ii promoter GO:0006366 368 0.013
regulation of gene expression epigenetic GO:0040029 128 0.013
positive regulation of cell communication GO:0010647 250 0.013
rho protein signal transduction GO:0007266 14 0.013
regulation of catalytic activity GO:0050790 185 0.013
multicellular organismal reproductive behavior GO:0033057 110 0.013
synaptic growth at neuromuscular junction GO:0051124 119 0.013
nucleus localization GO:0051647 34 0.013
regulation of ras protein signal transduction GO:0046578 93 0.012
negative regulation of cell death GO:0060548 81 0.012
protein phosphorylation GO:0006468 169 0.012
neuroblast division GO:0055057 35 0.012
gland development GO:0048732 191 0.012
regulation of phosphate metabolic process GO:0019220 210 0.012
regulation of actin filament based process GO:0032970 42 0.012
dna recombination GO:0006310 32 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.012
single organism biosynthetic process GO:0044711 206 0.012
Mouse
spermatid development GO:0007286 98 0.012
monocarboxylic acid catabolic process GO:0072329 10 0.012
positive regulation of protein transport GO:0051222 37 0.012
positive regulation of protein metabolic process GO:0051247 128 0.012
oocyte dorsal ventral axis specification GO:0007310 34 0.012
ras protein signal transduction GO:0007265 88 0.012
negative regulation of gene expression epigenetic GO:0045814 77 0.012
ribonucleotide metabolic process GO:0009259 145 0.012
early endosome to late endosome transport GO:0045022 3 0.012
positive regulation of nucleotide catabolic process GO:0030813 46 0.012
nucleoside metabolic process GO:0009116 127 0.012
response to radiation GO:0009314 155 0.012
developmental maturation GO:0021700 172 0.012
erk1 and erk2 cascade GO:0070371 39 0.012
positive regulation of rna metabolic process GO:0051254 271 0.011
regulation of phosphorylation GO:0042325 147 0.011
reproductive behavior GO:0019098 122 0.011
reproductive structure development GO:0048608 74 0.011
mapk cascade GO:0000165 107 0.011
neuronal stem cell division GO:0036445 35 0.011
positive regulation of catabolic process GO:0009896 105 0.011
cell cycle checkpoint GO:0000075 95 0.011
nuclear export GO:0051168 24 0.011
negative regulation of protein metabolic process GO:0051248 85 0.011
posttranscriptional regulation of gene expression GO:0010608 145 0.011
regulation of mapk cascade GO:0043408 92 0.011
determination of dorsal ventral asymmetry GO:0048262 3 0.011
learning GO:0007612 75 0.011
cellular ketone metabolic process GO:0042180 24 0.011
histolysis GO:0007559 102 0.011
ribonucleoside catabolic process GO:0042454 112 0.011
meiotic dna double strand break formation GO:0042138 1 0.011
wnt signaling pathway GO:0016055 98 0.011
guanosine containing compound metabolic process GO:1901068 74 0.011
g2 dna damage checkpoint GO:0031572 69 0.011
cellular macromolecular complex assembly GO:0034622 153 0.011
taxis GO:0042330 304 0.011
mitotic sister chromatid segregation GO:0000070 87 0.011
positive regulation of nucleoside metabolic process GO:0045979 47 0.011
stem cell development GO:0048864 79 0.011
regulation of nuclear division GO:0051783 58 0.011
cognition GO:0050890 141 0.010
positive regulation of rna biosynthetic process GO:1902680 266 0.010
regulation of phosphorus metabolic process GO:0051174 210 0.010
neuroblast proliferation GO:0007405 74 0.010
histone exchange GO:0043486 21 0.010
positive regulation of gtp catabolic process GO:0033126 43 0.010
camera type eye morphogenesis GO:0048593 2 0.010

pex2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.030
nervous system disease DOID:863 0 0.019
disease of anatomical entity DOID:7 0 0.019
inherited metabolic disorder DOID:655 0 0.018