Drosophila melanogaster

19 known processes

Tg (Dmel_CG7356)

Transglutaminase

(Aliases: CG7356,Dmel\CG7356)

Tg biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
steroid catabolic process GO:0006706 1 0.192
hormone catabolic process GO:0042447 3 0.124
anion homeostasis GO:0055081 3 0.101
lipid catabolic process GO:0016042 21 0.089
catabolic process GO:0009056 409 0.084
response to abiotic stimulus GO:0009628 341 0.074
organic cyclic compound catabolic process GO:1901361 168 0.071
toxin metabolic process GO:0009404 2 0.071
response to bacterium GO:0009617 198 0.064
organonitrogen compound metabolic process GO:1901564 318 0.063
response to organic substance GO:0010033 284 0.060
cell cell signaling involved in cell fate commitment GO:0045168 210 0.053
response to mercury ion GO:0046689 3 0.051
organic substance catabolic process GO:1901575 308 0.048
cellular catabolic process GO:0044248 372 0.045
lateral inhibition GO:0046331 206 0.044
response to biotic stimulus GO:0009607 294 0.043
vitamin biosynthetic process GO:0009110 1 0.042
response to organophosphorus GO:0046683 2 0.042
multi organism behavior GO:0051705 175 0.041
single organism catabolic process GO:0044712 228 0.040
carboxylic acid metabolic process GO:0019752 92 0.039
androgen metabolic process GO:0008209 1 0.039
response to external biotic stimulus GO:0043207 293 0.037
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.036
organic substance transport GO:0071702 257 0.035
negative regulation of cellular metabolic process GO:0031324 382 0.034
small molecule metabolic process GO:0044281 305 0.034
hormone metabolic process GO:0042445 33 0.031
regulation of developmental growth GO:0048638 174 0.030
response to endogenous stimulus GO:0009719 119 0.030
immune response GO:0006955 246 0.030
medium chain fatty acid metabolic process GO:0051791 1 0.030
developmental growth GO:0048589 280 0.029
defense response to other organism GO:0098542 225 0.029
secondary metabolic process GO:0019748 75 0.029
fat soluble vitamin metabolic process GO:0006775 1 0.029
axonogenesis GO:0007409 290 0.029
oxoacid metabolic process GO:0043436 103 0.029
negative regulation of nucleic acid templated transcription GO:1903507 240 0.028
positive regulation of macromolecule metabolic process GO:0010604 405 0.028
sensory perception of smell GO:0007608 80 0.028
negative regulation of gene expression GO:0010629 387 0.028
determination of adult lifespan GO:0008340 137 0.028
organic acid metabolic process GO:0006082 103 0.028
steroid metabolic process GO:0008202 20 0.028
transcription from rna polymerase ii promoter GO:0006366 368 0.027
response to nutrient levels GO:0031667 114 0.026
vesicle mediated transport GO:0016192 381 0.026
defense response GO:0006952 300 0.026
imaginal disc derived appendage development GO:0048737 399 0.026
aging GO:0007568 143 0.025
organonitrogen compound catabolic process GO:1901565 128 0.025
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.025
appendage morphogenesis GO:0035107 397 0.025
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.024
positive regulation of gene expression GO:0010628 290 0.024
regulation of intracellular signal transduction GO:1902531 236 0.024
regulation of immune system process GO:0002682 176 0.024
cellular nitrogen compound catabolic process GO:0044270 165 0.024
negative regulation of signal transduction GO:0009968 206 0.024
phagocytosis GO:0006909 215 0.023
regulation of response to stress GO:0080134 200 0.023
regionalization GO:0003002 416 0.023
endocytosis GO:0006897 310 0.023
regulation of cellular protein metabolic process GO:0032268 243 0.023
respiratory system development GO:0060541 213 0.023
response to organonitrogen compound GO:0010243 75 0.022
response to extracellular stimulus GO:0009991 116 0.022
cellular protein modification process GO:0006464 438 0.022
protein modification process GO:0036211 438 0.022
columnar cuboidal epithelial cell development GO:0002066 249 0.022
regulation of growth GO:0040008 233 0.021
immune effector process GO:0002252 98 0.021
oxidation reduction process GO:0055114 123 0.021
lauric acid metabolic process GO:0048252 1 0.021
negative regulation of response to stimulus GO:0048585 258 0.021
response to oxygen containing compound GO:1901700 200 0.021
post embryonic appendage morphogenesis GO:0035120 385 0.021
response to other organism GO:0051707 293 0.020
defense response to gram negative bacterium GO:0050829 94 0.020
regulation of anatomical structure morphogenesis GO:0022603 242 0.020
polyol biosynthetic process GO:0046173 3 0.020
cell adhesion GO:0007155 136 0.020
regulation of hydrolase activity GO:0051336 97 0.020
intracellular signal transduction GO:0035556 300 0.020
regulation of phosphorus metabolic process GO:0051174 210 0.020
xenobiotic catabolic process GO:0042178 1 0.020
single organism biosynthetic process GO:0044711 206 0.019
fat soluble vitamin biosynthetic process GO:0042362 1 0.019
appendage development GO:0048736 401 0.019
immune system process GO:0002376 347 0.019
peptide metabolic process GO:0006518 80 0.019
biological adhesion GO:0022610 138 0.019
body morphogenesis GO:0010171 2 0.019
protein localization GO:0008104 284 0.019
single organism behavior GO:0044708 391 0.019
chemotaxis GO:0006935 249 0.019
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.018
response to temperature stimulus GO:0009266 106 0.018
negative regulation of developmental process GO:0051093 201 0.018
negative regulation of rna biosynthetic process GO:1902679 240 0.018
axon development GO:0061564 297 0.018
nucleobase containing compound catabolic process GO:0034655 165 0.018
phosphorylation GO:0016310 294 0.018
cell proliferation GO:0008283 299 0.017
negative regulation of cell communication GO:0010648 223 0.017
wing disc morphogenesis GO:0007472 344 0.017
regulation of multicellular organismal development GO:2000026 414 0.017
organelle fission GO:0048285 340 0.017
aromatic compound catabolic process GO:0019439 166 0.017
regulation of immune response GO:0050776 118 0.017
response to lipopolysaccharide GO:0032496 4 0.017
regulation of cell morphogenesis GO:0022604 163 0.017
negative regulation of cellular protein metabolic process GO:0032269 85 0.017
purine nucleotide metabolic process GO:0006163 146 0.017
neurological system process GO:0050877 358 0.017
carbohydrate derivative metabolic process GO:1901135 217 0.017
cellular amino acid metabolic process GO:0006520 61 0.017
secondary metabolite catabolic process GO:0090487 1 0.017
nuclear division GO:0000280 332 0.017
regulation of anatomical structure size GO:0090066 163 0.017
lipid metabolic process GO:0006629 121 0.016
positive regulation of cellular biosynthetic process GO:0031328 316 0.016
toxin catabolic process GO:0009407 1 0.016
positive regulation of signaling GO:0023056 243 0.016
localization of cell GO:0051674 257 0.016
meiotic nuclear division GO:0007126 151 0.016
response to nitrogen compound GO:1901698 90 0.016
heterocycle catabolic process GO:0046700 166 0.016
kidney development GO:0001822 3 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.016
regulation of protein metabolic process GO:0051246 256 0.016
imaginal disc derived appendage morphogenesis GO:0035114 395 0.016
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.015
regulation of catalytic activity GO:0050790 185 0.015
negative regulation of signaling GO:0023057 219 0.015
positive regulation of phosphate metabolic process GO:0045937 139 0.015
glycosyl compound metabolic process GO:1901657 127 0.015
open tracheal system development GO:0007424 204 0.015
response to organic cyclic compound GO:0014070 89 0.014
imaginal disc derived wing morphogenesis GO:0007476 337 0.014
positive regulation of catabolic process GO:0009896 105 0.014
multicellular organismal aging GO:0010259 140 0.014
regulation of cell cycle GO:0051726 291 0.014
cellular ketone metabolic process GO:0042180 24 0.014
cell migration GO:0016477 238 0.014
forebrain development GO:0030900 2 0.014
cellular hormone metabolic process GO:0034754 23 0.014
insecticide catabolic process GO:0046701 1 0.014
negative regulation of biosynthetic process GO:0009890 277 0.014
morphogenesis of an epithelium GO:0002009 276 0.014
regulation of multi organism process GO:0043900 131 0.014
taxis GO:0042330 304 0.013
positive regulation of response to stimulus GO:0048584 323 0.013
telencephalon development GO:0021537 2 0.013
establishment of localization in cell GO:0051649 402 0.013
aggressive behavior GO:0002118 63 0.013
enzyme linked receptor protein signaling pathway GO:0007167 179 0.013
regulation of cell proliferation GO:0042127 163 0.013
regulation of cell differentiation GO:0045595 302 0.013
compound eye development GO:0048749 307 0.013
central nervous system development GO:0007417 201 0.013
positive regulation of hemocyte proliferation GO:0035208 4 0.013
establishment of protein localization GO:0045184 163 0.013
ras protein signal transduction GO:0007265 88 0.013
negative regulation of cellular biosynthetic process GO:0031327 277 0.013
regulation of molecular function GO:0065009 217 0.013
growth GO:0040007 359 0.013
response to ethanol GO:0045471 59 0.013
nucleoside catabolic process GO:0009164 112 0.013
cellular macromolecule localization GO:0070727 220 0.013
cellular response to chemical stimulus GO:0070887 199 0.013
purine ribonucleoside metabolic process GO:0046128 127 0.012
purine containing compound metabolic process GO:0072521 155 0.012
purine ribonucleotide metabolic process GO:0009150 145 0.012
cellular response to organic substance GO:0071310 132 0.012
intracellular transport GO:0046907 228 0.012
positive regulation of phosphorus metabolic process GO:0010562 139 0.012
positive regulation of cell migration GO:0030335 2 0.012
nucleobase containing small molecule metabolic process GO:0055086 174 0.012
death GO:0016265 284 0.012
homeostatic process GO:0042592 199 0.012
chromosome segregation GO:0007059 157 0.012
vitamin metabolic process GO:0006766 2 0.012
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.012
chromosome organization GO:0051276 360 0.012
negative regulation of transcription dna templated GO:0045892 237 0.012
regulation of humoral immune response GO:0002920 51 0.012
actin cytoskeleton organization GO:0030036 206 0.012
adult behavior GO:0030534 137 0.012
defense response to bacterium GO:0042742 178 0.012
innate immune response GO:0045087 144 0.012
cell death GO:0008219 279 0.012
ribonucleoside triphosphate catabolic process GO:0009203 108 0.011
negative regulation of protein metabolic process GO:0051248 85 0.011
axon guidance GO:0007411 233 0.011
positive regulation of cell communication GO:0010647 250 0.011
positive regulation of biosynthetic process GO:0009891 316 0.011
small gtpase mediated signal transduction GO:0007264 88 0.011
regulation of cellular component biogenesis GO:0044087 201 0.011
sensory perception GO:0007600 196 0.011
cellular amine metabolic process GO:0044106 12 0.011
negative regulation of cell differentiation GO:0045596 143 0.011
ribonucleotide metabolic process GO:0009259 145 0.011
meiotic cell cycle GO:0051321 171 0.011
multi multicellular organism process GO:0044706 123 0.011
proteolysis GO:0006508 192 0.011
dendrite morphogenesis GO:0048813 199 0.011
wnt signaling pathway GO:0016055 98 0.011
regulation of proteolysis GO:0030162 87 0.011
glutathione metabolic process GO:0006749 37 0.010
protein maturation GO:0051604 71 0.010
immune response activating signal transduction GO:0002757 2 0.010
microtubule organizing center organization GO:0031023 168 0.010
negative regulation of rna metabolic process GO:0051253 251 0.010
germ cell migration GO:0008354 43 0.010
regulation of production of molecular mediator of immune response GO:0002700 44 0.010
nucleoside metabolic process GO:0009116 127 0.010
nitrogen compound transport GO:0071705 85 0.010
gene silencing GO:0016458 138 0.010
actin filament based process GO:0030029 220 0.010
cellular homeostasis GO:0019725 80 0.010
gland development GO:0048732 191 0.010
protein transport GO:0015031 155 0.010
purine ribonucleoside catabolic process GO:0046130 112 0.010
macromolecule catabolic process GO:0009057 161 0.010
neuron projection guidance GO:0097485 241 0.010
epithelial cell development GO:0002064 274 0.010
regulation of antimicrobial humoral response GO:0002759 50 0.010
negative regulation of peptide hormone processing GO:0060570 1 0.010

Tg disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.035
cardiovascular system disease DOID:1287 0 0.030
nervous system disease DOID:863 0 0.015
hypertension DOID:10763 0 0.014
artery disease DOID:0050828 0 0.014
vascular disease DOID:178 0 0.014
disease of metabolism DOID:0014667 0 0.011
inherited metabolic disorder DOID:655 0 0.010