Drosophila melanogaster

25 known processes

TM9SF4 (Dmel_CG7364)

CG7364 gene product from transcript CG7364-RA

(Aliases: n(2)k07245,CG7364,CG16861,BG:DS00797.1,Dmel\CG7364)

TM9SF4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
immune system process GO:0002376 347 0.642
defense response to bacterium GO:0042742 178 0.507
regulation of biosynthetic process of antibacterial peptides active against gram positive bacteria GO:0002816 3 0.472
defense response to other organism GO:0098542 225 0.382
defense response GO:0006952 300 0.343
innate immune response GO:0045087 144 0.289
regulation of defense response GO:0031347 102 0.276
response to biotic stimulus GO:0009607 294 0.273
immune response GO:0006955 246 0.230
positive regulation of response to stimulus GO:0048584 323 0.216
response to external biotic stimulus GO:0043207 293 0.193
response to other organism GO:0051707 293 0.167
pattern recognition receptor signaling pathway GO:0002221 2 0.153
defense response to gram positive bacterium GO:0050830 41 0.141
defense response to fungus GO:0050832 48 0.136
carbohydrate derivative metabolic process GO:1901135 217 0.128
organonitrogen compound metabolic process GO:1901564 318 0.125
immune response activating signal transduction GO:0002757 2 0.121
immune effector process GO:0002252 98 0.117
response to bacterium GO:0009617 198 0.115
antibacterial humoral response GO:0019731 44 0.104
intracellular signal transduction GO:0035556 300 0.103
defense response to gram negative bacterium GO:0050829 94 0.101
regulation of immune system process GO:0002682 176 0.094
positive regulation of signal transduction GO:0009967 223 0.093
actin filament based process GO:0030029 220 0.090
response to organic substance GO:0010033 284 0.088
positive regulation of cell communication GO:0010647 250 0.087
regulation of immune response GO:0050776 118 0.086
response to fungus GO:0009620 50 0.085
regulation of response to stress GO:0080134 200 0.079
cell cell signaling involved in cell fate commitment GO:0045168 210 0.076
antifungal humoral response GO:0019732 12 0.067
negative regulation of signaling GO:0023057 219 0.059
antimicrobial humoral response GO:0019730 99 0.059
lateral inhibition GO:0046331 206 0.059
innate immune response activating signal transduction GO:0002758 2 0.058
antibacterial peptide production GO:0002778 22 0.058
humoral immune response GO:0006959 117 0.057
protein modification process GO:0036211 438 0.055
response to lipopolysaccharide GO:0032496 4 0.054
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.054
protein complex biogenesis GO:0070271 201 0.053
glycoprotein biosynthetic process GO:0009101 41 0.053
antimicrobial peptide biosynthetic process GO:0002777 38 0.053
peptide metabolic process GO:0006518 80 0.052
response to virus GO:0009615 28 0.051
regulation of intracellular signal transduction GO:1902531 236 0.051
regulation of phosphate metabolic process GO:0019220 210 0.051
positive regulation of signaling GO:0023056 243 0.051
compound eye development GO:0048749 307 0.051
carbohydrate metabolic process GO:0005975 82 0.049
single organism carbohydrate metabolic process GO:0044723 72 0.048
single organism behavior GO:0044708 391 0.048
membrane organization GO:0061024 112 0.048
single organism biosynthetic process GO:0044711 206 0.047
regulation of immune effector process GO:0002697 52 0.047
positive regulation of defense response GO:0031349 59 0.047
regulation of antibacterial peptide production GO:0002786 22 0.047
organic substance transport GO:0071702 257 0.047
wing disc morphogenesis GO:0007472 344 0.047
neuromuscular junction development GO:0007528 149 0.046
vesicle mediated transport GO:0016192 381 0.046
negative regulation of cell communication GO:0010648 223 0.045
phagocytosis GO:0006909 215 0.045
eye morphogenesis GO:0048592 260 0.045
establishment of localization in cell GO:0051649 402 0.043
connective tissue development GO:0061448 3 0.043
negative regulation of cellular metabolic process GO:0031324 382 0.042
protein localization GO:0008104 284 0.042
regulation of multi organism process GO:0043900 131 0.041
rna processing GO:0006396 147 0.041
regulation of protein metabolic process GO:0051246 256 0.041
synaptic transmission GO:0007268 288 0.041
intracellular transport GO:0046907 228 0.041
cytoplasmic transport GO:0016482 130 0.041
glycoprotein metabolic process GO:0009100 41 0.041
cellular protein modification process GO:0006464 438 0.040
carbohydrate derivative biosynthetic process GO:1901137 85 0.040
appendage morphogenesis GO:0035107 397 0.039
organic substance catabolic process GO:1901575 308 0.039
cellular macromolecule localization GO:0070727 220 0.039
cellular response to molecule of bacterial origin GO:0071219 3 0.039
protein complex assembly GO:0006461 200 0.039
negative regulation of gene expression GO:0010629 387 0.038
homeostatic process GO:0042592 199 0.038
mapk cascade GO:0000165 107 0.038
regulation of cellular protein metabolic process GO:0032268 243 0.038
cellular response to organic substance GO:0071310 132 0.038
positive regulation of immune response GO:0050778 63 0.037
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.037
regulation of antibacterial peptide biosynthetic process GO:0002808 22 0.037
circadian rhythm GO:0007623 105 0.037
oxoacid metabolic process GO:0043436 103 0.037
catabolic process GO:0009056 409 0.037
macromolecule catabolic process GO:0009057 161 0.036
regulation of transport GO:0051049 181 0.036
o glycan processing GO:0016266 3 0.036
positive regulation of cellular biosynthetic process GO:0031328 316 0.036
production of molecular mediator of immune response GO:0002440 46 0.035
antibacterial peptide biosynthetic process GO:0002780 22 0.035
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.035
circadian sleep wake cycle process GO:0022410 24 0.035
phosphorylation GO:0016310 294 0.035
cell proliferation GO:0008283 299 0.035
imaginal disc derived wing morphogenesis GO:0007476 337 0.034
locomotory behavior GO:0007626 176 0.034
compound eye morphogenesis GO:0001745 249 0.034
regulation of peptidoglycan recognition protein signaling pathway GO:0061058 4 0.034
response to wounding GO:0009611 94 0.034
cellular amide metabolic process GO:0043603 80 0.034
eye development GO:0001654 323 0.033
regulation of innate immune response GO:0045088 71 0.033
cellular protein localization GO:0034613 160 0.033
male gamete generation GO:0048232 201 0.032
regulation of antimicrobial humoral response GO:0002759 50 0.031
regulation of localization GO:0032879 275 0.031
negative regulation of signal transduction GO:0009968 206 0.030
cell migration GO:0016477 238 0.030
post embryonic appendage morphogenesis GO:0035120 385 0.030
wnt signaling pathway GO:0016055 98 0.030
appendage development GO:0048736 401 0.030
intracellular protein transport GO:0006886 104 0.029
response to nutrient levels GO:0031667 114 0.029
cellular catabolic process GO:0044248 372 0.029
antimicrobial peptide production GO:0002775 46 0.029
salivary gland development GO:0007431 162 0.029
positive regulation of biosynthetic process GO:0009891 316 0.028
macromolecular complex assembly GO:0065003 256 0.028
nuclear division GO:0000280 332 0.027
carbohydrate derivative catabolic process GO:1901136 118 0.027
heterocycle catabolic process GO:0046700 166 0.027
nucleobase containing small molecule metabolic process GO:0055086 174 0.027
single organism intracellular transport GO:1902582 207 0.026
spermatogenesis GO:0007283 200 0.026
positive regulation of humoral immune response GO:0002922 28 0.026
anatomical structure homeostasis GO:0060249 97 0.026
regulation of defense response to bacterium GO:1900424 30 0.026
small molecule metabolic process GO:0044281 305 0.026
negative regulation of peptidoglycan recognition protein signaling pathway GO:0061060 3 0.026
morphogenesis of an epithelium GO:0002009 276 0.025
digestive system development GO:0055123 149 0.025
regionalization GO:0003002 416 0.025
chromosome organization GO:0051276 360 0.025
response to starvation GO:0042594 97 0.025
cell adhesion GO:0007155 136 0.025
tissue morphogenesis GO:0048729 297 0.025
regulation of humoral immune response GO:0002920 51 0.025
organonitrogen compound catabolic process GO:1901565 128 0.025
organelle assembly GO:0070925 198 0.025
muscle organ development GO:0007517 127 0.025
protein glycosylation GO:0006486 32 0.025
organelle fission GO:0048285 340 0.025
body morphogenesis GO:0010171 2 0.024
posttranscriptional regulation of gene expression GO:0010608 145 0.024
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.024
regulation of cell differentiation GO:0045595 302 0.024
activation of innate immune response GO:0002218 4 0.024
sperm individualization GO:0007291 48 0.024
positive regulation of jun kinase activity GO:0043507 4 0.024
regulation of antimicrobial peptide production GO:0002784 44 0.024
neurological system process GO:0050877 358 0.024
negative regulation of response to stimulus GO:0048585 258 0.023
localization of cell GO:0051674 257 0.023
positive regulation of intracellular signal transduction GO:1902533 116 0.023
regulation of gene silencing GO:0060968 63 0.023
aromatic compound catabolic process GO:0019439 166 0.023
embryo development ending in birth or egg hatching GO:0009792 152 0.023
protein transport GO:0015031 155 0.023
tube morphogenesis GO:0035239 191 0.023
gland development GO:0048732 191 0.023
positive regulation of immune system process GO:0002684 68 0.023
kidney development GO:0001822 3 0.022
cellular amino acid metabolic process GO:0006520 61 0.022
establishment of protein localization GO:0045184 163 0.022
dorsal ventral pattern formation GO:0009953 133 0.022
regulation of mapk cascade GO:0043408 92 0.022
regulation of molecular function GO:0065009 217 0.022
ras protein signal transduction GO:0007265 88 0.022
cell cycle checkpoint GO:0000075 95 0.022
defense response to virus GO:0051607 23 0.022
signal transduction by phosphorylation GO:0023014 107 0.022
positive regulation of antibacterial peptide biosynthetic process GO:0006963 20 0.021
negative regulation of biosynthetic process GO:0009890 277 0.021
response to extracellular stimulus GO:0009991 116 0.021
spermatid differentiation GO:0048515 114 0.021
negative regulation of cellular biosynthetic process GO:0031327 277 0.021
melanization defense response GO:0035006 45 0.021
negative regulation of nucleic acid templated transcription GO:1903507 240 0.021
stress activated protein kinase signaling cascade GO:0031098 55 0.021
immune system development GO:0002520 57 0.021
regulation of organelle organization GO:0033043 196 0.021
regulation of cellular amide metabolic process GO:0034248 39 0.021
carboxylic acid metabolic process GO:0019752 92 0.021
cellular homeostasis GO:0019725 80 0.021
mitotic nuclear division GO:0007067 213 0.021
imaginal disc derived appendage development GO:0048737 399 0.020
nitrogen compound transport GO:0071705 85 0.020
positive regulation of gene expression GO:0010628 290 0.020
cellular response to chemical stimulus GO:0070887 199 0.020
regulation of antimicrobial peptide biosynthetic process GO:0002805 38 0.020
immune response regulating signaling pathway GO:0002764 2 0.020
cellular response to lipopolysaccharide GO:0071222 3 0.020
imaginal disc derived appendage morphogenesis GO:0035114 395 0.020
monocarboxylic acid transport GO:0015718 3 0.020
single organism cellular localization GO:1902580 180 0.020
cell recognition GO:0008037 102 0.020
protein phosphorylation GO:0006468 169 0.020
segmentation GO:0035282 207 0.020
positive regulation of phosphorus metabolic process GO:0010562 139 0.019
circadian behavior GO:0048512 76 0.019
circadian sleep wake cycle GO:0042745 28 0.019
positive regulation of rna metabolic process GO:0051254 271 0.019
epithelial cell development GO:0002064 274 0.019
actin cytoskeleton organization GO:0030036 206 0.019
hematopoietic or lymphoid organ development GO:0048534 57 0.019
regulation of notch signaling pathway GO:0008593 100 0.019
organonitrogen compound biosynthetic process GO:1901566 117 0.019
positive regulation of phosphate metabolic process GO:0045937 139 0.019
response to dsrna GO:0043331 15 0.019
positive regulation of response to biotic stimulus GO:0002833 31 0.019
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.018
organic acid metabolic process GO:0006082 103 0.018
tube development GO:0035295 244 0.018
extrinsic apoptotic signaling pathway GO:0097191 1 0.018
hemocyte differentiation GO:0042386 38 0.018
mrna processing GO:0006397 104 0.018
gastrulation with mouth forming first GO:0001703 36 0.018
regulation of wnt signaling pathway GO:0030111 68 0.018
cell death GO:0008219 279 0.018
regulation of phosphorus metabolic process GO:0051174 210 0.018
positive regulation of antimicrobial peptide biosynthetic process GO:0002807 26 0.018
negative regulation of rna metabolic process GO:0051253 251 0.018
adult locomotory behavior GO:0008344 76 0.018
positive regulation of defense response to bacterium GO:1900426 23 0.018
regulation of catalytic activity GO:0050790 185 0.018
negative regulation of multicellular organismal process GO:0051241 142 0.018
endocytosis GO:0006897 310 0.018
protein complex localization GO:0031503 4 0.018
cellular component assembly involved in morphogenesis GO:0010927 151 0.018
posttranscriptional gene silencing GO:0016441 46 0.017
regulation of response to biotic stimulus GO:0002831 63 0.017
mrna metabolic process GO:0016071 124 0.017
negative regulation of developmental process GO:0051093 201 0.017
purine ribonucleoside catabolic process GO:0046130 112 0.017
organophosphate metabolic process GO:0019637 195 0.017
organic cyclic compound catabolic process GO:1901361 168 0.017
actin filament based movement GO:0030048 26 0.017
cellular response to extracellular stimulus GO:0031668 64 0.017
positive regulation of phosphorylation GO:0042327 87 0.017
neuromuscular synaptic transmission GO:0007274 67 0.017
rhythmic process GO:0048511 106 0.017
posttranscriptional gene silencing by rna GO:0035194 45 0.017
regulation of cellular ketone metabolic process GO:0010565 3 0.017
hemopoiesis GO:0030097 46 0.017
regulation of response to external stimulus GO:0032101 115 0.017
regulation of nf kappab import into nucleus GO:0042345 1 0.017
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.017
sensory organ morphogenesis GO:0090596 260 0.017
multicellular organismal homeostasis GO:0048871 41 0.016
regulation of production of molecular mediator of immune response GO:0002700 44 0.016
positive regulation of protein metabolic process GO:0051247 128 0.016
muscle attachment GO:0016203 36 0.016
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.016
reproductive system development GO:0061458 74 0.016
columnar cuboidal epithelial cell development GO:0002066 249 0.016
glycosyl compound metabolic process GO:1901657 127 0.016
negative regulation of defense response to bacterium GO:1900425 7 0.016
positive regulation of cellular protein metabolic process GO:0032270 118 0.016
macromolecule glycosylation GO:0043413 32 0.016
gene silencing GO:0016458 138 0.016
response to organophosphorus GO:0046683 2 0.016
positive regulation of apoptotic signaling pathway GO:2001235 4 0.016
positive regulation of macromolecule metabolic process GO:0010604 405 0.015
endomembrane system organization GO:0010256 119 0.015
epithelial tube morphogenesis GO:0060562 88 0.015
regulation of organ formation GO:0003156 3 0.015
regulation of mitotic cell cycle GO:0007346 190 0.015
regulation of cellular amine metabolic process GO:0033238 3 0.015
morphogenesis of a branching epithelium GO:0061138 45 0.015
ion transport GO:0006811 145 0.015
regulation of multicellular organismal development GO:2000026 414 0.015
nf kappab import into nucleus GO:0042348 1 0.015
reproductive structure development GO:0048608 74 0.015
regulation of protein import into nucleus GO:0042306 28 0.015
negative regulation of transcription dna templated GO:0045892 237 0.015
positive regulation of catalytic activity GO:0043085 118 0.015
regulation of hydrolase activity GO:0051336 97 0.015
regulation of anatomical structure size GO:0090066 163 0.015
chromatin remodeling GO:0006338 72 0.015
gene silencing by rna GO:0031047 57 0.015
detection of chemical stimulus GO:0009593 93 0.014
nucleoside catabolic process GO:0009164 112 0.014
regulation of toll signaling pathway GO:0008592 17 0.014
cellularization GO:0007349 90 0.014
gtp metabolic process GO:0046039 72 0.014
cellular response to biotic stimulus GO:0071216 4 0.014
regulation of behavior GO:0050795 75 0.014
regulation of stress activated mapk cascade GO:0032872 41 0.014
spermatid development GO:0007286 98 0.014
muscle structure development GO:0061061 224 0.014
neuron recognition GO:0008038 101 0.014
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.014
regulation of protein transport GO:0051223 57 0.014
digestive tract development GO:0048565 149 0.014
regulation of phosphorylation GO:0042325 147 0.014
embryonic pattern specification GO:0009880 174 0.014
regulation of cell cycle GO:0051726 291 0.014
cellular lipid metabolic process GO:0044255 83 0.014
positive regulation of developmental process GO:0051094 143 0.013
larval development GO:0002164 104 0.013
single organism nuclear import GO:1902593 51 0.013
positive regulation of nucleic acid templated transcription GO:1903508 266 0.013
actin filament organization GO:0007015 126 0.013
central nervous system development GO:0007417 201 0.013
regulation of embryonic development GO:0045995 68 0.013
regulation of gene expression epigenetic GO:0040029 128 0.013
rna splicing GO:0008380 83 0.013
cellular nitrogen compound catabolic process GO:0044270 165 0.013
biosynthetic process of antibacterial peptides active against gram negative bacteria GO:0002812 14 0.013
dna integrity checkpoint GO:0031570 81 0.013
protein polymerization GO:0051258 42 0.013
small gtpase mediated signal transduction GO:0007264 88 0.013
cellular amine metabolic process GO:0044106 12 0.013
regulation of cell size GO:0008361 63 0.013
regulation of endopeptidase activity GO:0052548 36 0.013
positive regulation of hydrolase activity GO:0051345 78 0.013
stem cell development GO:0048864 79 0.013
positive regulation of antimicrobial peptide production GO:0002225 28 0.013
apoptotic cell clearance GO:0043277 14 0.013
chromosome segregation GO:0007059 157 0.013
purine nucleoside catabolic process GO:0006152 112 0.013
regulation of cellular component size GO:0032535 98 0.013
apoptotic process GO:0006915 159 0.013
toll signaling pathway GO:0008063 25 0.013
protein import GO:0017038 55 0.013
positive regulation of molecular function GO:0044093 136 0.013
response to nitrogen compound GO:1901698 90 0.012
heterochromatin organization GO:0070828 25 0.012
mucosal immune response GO:0002385 10 0.012
amine metabolic process GO:0009308 12 0.012
regulation of cellular localization GO:0060341 136 0.012
response to endogenous stimulus GO:0009719 119 0.012
sex differentiation GO:0007548 81 0.012
positive regulation of behavior GO:0048520 19 0.012
response to organic cyclic compound GO:0014070 89 0.012
secretion GO:0046903 109 0.012
dna metabolic process GO:0006259 227 0.012
positive regulation of immune effector process GO:0002699 28 0.012
ribonucleoside catabolic process GO:0042454 112 0.012
translation GO:0006412 69 0.012
alternative mrna splicing via spliceosome GO:0000380 60 0.012
activation of cysteine type endopeptidase activity GO:0097202 17 0.012
regulation of transferase activity GO:0051338 58 0.012
detection of stimulus GO:0051606 156 0.012
positive regulation of mapk cascade GO:0043410 63 0.012
actin mediated cell contraction GO:0070252 21 0.012
cell motility GO:0048870 251 0.012
positive regulation of cellular component organization GO:0051130 156 0.012
negative regulation of rna biosynthetic process GO:1902679 240 0.012
organ or tissue specific immune response GO:0002251 10 0.012
outflow tract morphogenesis GO:0003151 4 0.012
telencephalon development GO:0021537 2 0.012
positive regulation of protein transport GO:0051222 37 0.012
regulation of protein modification process GO:0031399 112 0.011
proteolysis GO:0006508 192 0.011
phagocytosis engulfment GO:0006911 11 0.011
positive regulation of response to external stimulus GO:0032103 44 0.011
pigment metabolic process GO:0042440 84 0.011
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 4 0.011
aging GO:0007568 143 0.011
nucleocytoplasmic transport GO:0006913 72 0.011
chaeta development GO:0022416 97 0.011
death GO:0016265 284 0.011
hemolymph coagulation GO:0042381 10 0.011
chromatin organization GO:0006325 207 0.011
embryonic morphogenesis GO:0048598 206 0.011
jak stat cascade GO:0007259 49 0.011
digestive tract morphogenesis GO:0048546 127 0.011
pigmentation GO:0043473 75 0.011
negative regulation of immune system process GO:0002683 50 0.011
long term memory GO:0007616 62 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.011
cation transport GO:0006812 110 0.011
nucleotide metabolic process GO:0009117 161 0.011
negative regulation of cell cycle GO:0045786 116 0.011
regulation of cytoskeleton organization GO:0051493 89 0.011
epithelial cell differentiation GO:0030855 322 0.011
wing disc dorsal ventral pattern formation GO:0048190 47 0.011
stem cell differentiation GO:0048863 117 0.011
sleep GO:0030431 49 0.011
biological adhesion GO:0022610 138 0.011
regulation of cell development GO:0060284 215 0.011
regulation of circadian rhythm GO:0042752 49 0.011
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.011
locomotor rhythm GO:0045475 56 0.011
cell cycle arrest GO:0007050 4 0.011
purine containing compound metabolic process GO:0072521 155 0.011
negative regulation of cell differentiation GO:0045596 143 0.011
regulation of circadian sleep wake cycle sleep GO:0045187 21 0.010
striated muscle cell differentiation GO:0051146 90 0.010
ribonucleotide metabolic process GO:0009259 145 0.010
rna 3 end processing GO:0031123 45 0.010
negative regulation of cellular component organization GO:0051129 108 0.010
purine ribonucleoside metabolic process GO:0046128 127 0.010
response to abiotic stimulus GO:0009628 341 0.010
kidney epithelium development GO:0072073 3 0.010
positive regulation of innate immune response GO:0045089 38 0.010
positive regulation of cellular component biogenesis GO:0044089 80 0.010
melanin metabolic process GO:0006582 47 0.010
salivary gland morphogenesis GO:0007435 145 0.010
regulation of apoptotic process GO:0042981 130 0.010
cellular response to carbohydrate stimulus GO:0071322 4 0.010
single organism catabolic process GO:0044712 228 0.010
adult behavior GO:0030534 137 0.010
molting cycle chitin based cuticle GO:0007591 56 0.010
detection of stimulus involved in sensory perception GO:0050906 92 0.010
nuclear transport GO:0051169 72 0.010
regulation of nucleocytoplasmic transport GO:0046822 35 0.010
peptide biosynthetic process GO:0043043 42 0.010
hematopoietic progenitor cell differentiation GO:0002244 1 0.010
muscle tissue morphogenesis GO:0060415 2 0.010

TM9SF4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.027
disease of cellular proliferation DOID:14566 0 0.027
organ system cancer DOID:0050686 0 0.018
disease of anatomical entity DOID:7 0 0.017