Drosophila melanogaster

186 known processes

Rpd3 (Dmel_CG7471)

CG7471 gene product from transcript CG7471-RA

(Aliases: HDAC1,DmHDAC1,dHDAC1,RPD3,Su(var)328,dRPD3,Su(var)326,Hdac1,Su(var)3-26,dmHDA401,CG7471,drpd3,HDAC-1,hdac1,dHDAC-1,HDAC,dRpd3,Rpd3/HDAC,Dmel\CG7471,l(3)64Cc,E(var)3-64BC,l(3)04556,DHDAC1,rpd[3],rpd3,DRpd3)

Rpd3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chromosome organization GO:0051276 360 0.997
negative regulation of transcription dna templated GO:0045892 237 0.991
negative regulation of rna biosynthetic process GO:1902679 240 0.985
chromatin remodeling GO:0006338 72 0.976
Human
peptidyl lysine modification GO:0018205 57 0.974
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.973
negative regulation of nucleic acid templated transcription GO:1903507 240 0.971
regulation of gene expression epigenetic GO:0040029 128 0.971
negative regulation of gene expression GO:0010629 387 0.965
negative regulation of gene expression epigenetic GO:0045814 77 0.956
protein dna complex subunit organization GO:0071824 86 0.953
meiotic nuclear division GO:0007126 151 0.951
meiotic cell cycle GO:0051321 171 0.944
chromatin silencing GO:0006342 76 0.935
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.931
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.929
nucleosome organization GO:0034728 59 0.924
regulation of mitotic cell cycle phase transition GO:1901990 130 0.921
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.907
negative regulation of biosynthetic process GO:0009890 277 0.897
chromatin modification GO:0016568 147 0.891
g2 dna damage checkpoint GO:0031572 69 0.889
intracellular signal transduction GO:0035556 300 0.887
Mouse Worm
sister chromatid segregation GO:0000819 92 0.887
methylation GO:0032259 47 0.871
negative regulation of cellular biosynthetic process GO:0031327 277 0.870
organelle fission GO:0048285 340 0.859
mitotic sister chromatid segregation GO:0000070 87 0.856
dna integrity checkpoint GO:0031570 81 0.851
dna packaging GO:0006323 91 0.848
nuclear division GO:0000280 332 0.848
gonad development GO:0008406 50 0.840
Worm
cellular protein modification process GO:0006464 438 0.839
dna metabolic process GO:0006259 227 0.839
Worm
regulation of cell cycle phase transition GO:1901987 130 0.837
chromatin organization GO:0006325 207 0.831
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.830
mitotic g2 m transition checkpoint GO:0044818 70 0.830
cell cycle checkpoint GO:0000075 95 0.826
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.817
Human Worm
dna damage checkpoint GO:0000077 78 0.813
cell cycle phase transition GO:0044770 140 0.796
body morphogenesis GO:0010171 2 0.794
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.786
catabolic process GO:0009056 409 0.763
histone modification GO:0016570 106 0.679
mitotic dna damage checkpoint GO:0044773 74 0.655
atp dependent chromatin remodeling GO:0043044 22 0.632
Human
reproductive system development GO:0061458 74 0.632
Worm
regulation of catabolic process GO:0009894 170 0.624
sex differentiation GO:0007548 81 0.591
Worm
regulation of intracellular signal transduction GO:1902531 236 0.580
Mouse Worm
chromatin assembly GO:0031497 48 0.571
positive regulation of rna metabolic process GO:0051254 271 0.550
Human Worm
nucleobase containing compound catabolic process GO:0034655 165 0.546
negative regulation of cell cycle phase transition GO:1901988 103 0.520
protein modification process GO:0036211 438 0.515
negative regulation of mitotic cell cycle GO:0045930 109 0.493
mitotic cell cycle phase transition GO:0044772 138 0.491
gene silencing GO:0016458 138 0.477
embryo development ending in birth or egg hatching GO:0009792 152 0.469
Zebrafish Worm
mitotic g2 dna damage checkpoint GO:0007095 69 0.458
apoptotic process GO:0006915 159 0.431
Mouse Worm
single organism catabolic process GO:0044712 228 0.426
taxis GO:0042330 304 0.422
glycosyl compound catabolic process GO:1901658 112 0.417
negative regulation of cellular metabolic process GO:0031324 382 0.412
cellular nitrogen compound catabolic process GO:0044270 165 0.411
rna interference GO:0016246 27 0.410
Worm
axon development GO:0061564 297 0.409
regulation of chromosome organization GO:0033044 64 0.407
development of primary sexual characteristics GO:0045137 50 0.390
Worm
cell death GO:0008219 279 0.382
Mouse Worm
regulation of mitotic sister chromatid separation GO:0010965 28 0.380
negative regulation of cell communication GO:0010648 223 0.376
Human Mouse Worm
regulation of mitotic cell cycle GO:0007346 190 0.376
transcription from rna polymerase ii promoter GO:0006366 368 0.374
negative regulation of cell cycle GO:0045786 116 0.366
vesicle mediated transport GO:0016192 381 0.366
Worm
histone h3 k4 methylation GO:0051568 16 0.366
chemotaxis GO:0006935 249 0.351
histone acetylation GO:0016573 38 0.351
neuron projection guidance GO:0097485 241 0.351
macromolecular complex assembly GO:0065003 256 0.349
positive regulation of nucleic acid templated transcription GO:1903508 266 0.348
Human Worm
posttranscriptional regulation of gene expression GO:0010608 145 0.347
Worm
chromosome segregation GO:0007059 157 0.336
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.334
organic substance catabolic process GO:1901575 308 0.332
regulation of meiosis GO:0040020 3 0.331
reproductive structure development GO:0048608 74 0.329
Worm
rna splicing GO:0008380 83 0.324
ribonucleotide catabolic process GO:0009261 109 0.314
nucleotide catabolic process GO:0009166 109 0.312
cellular catabolic process GO:0044248 372 0.312
larval development GO:0002164 104 0.307
Worm
protein acetylation GO:0006473 39 0.306
positive regulation of response to stimulus GO:0048584 323 0.305
nucleoside triphosphate metabolic process GO:0009141 120 0.298
small molecule metabolic process GO:0044281 305 0.288
negative regulation of cell cycle process GO:0010948 109 0.287
mitotic nuclear division GO:0007067 213 0.279
organic cyclic compound catabolic process GO:1901361 168 0.273
blastoderm segmentation GO:0007350 159 0.272
positive regulation of macromolecule metabolic process GO:0010604 405 0.264
Human Worm
purine ribonucleotide catabolic process GO:0009154 109 0.262
cellular response to dna damage stimulus GO:0006974 223 0.262
oocyte differentiation GO:0009994 145 0.262
cellular macromolecular complex assembly GO:0034622 153 0.261
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.257
purine nucleoside triphosphate catabolic process GO:0009146 108 0.253
heterocycle catabolic process GO:0046700 166 0.248
internal peptidyl lysine acetylation GO:0018393 38 0.243
carbohydrate derivative catabolic process GO:1901136 118 0.243
purine nucleoside catabolic process GO:0006152 112 0.239
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.227
aromatic compound catabolic process GO:0019439 166 0.225
tube development GO:0035295 244 0.222
Zebrafish Worm
nucleotide metabolic process GO:0009117 161 0.222
mitotic dna integrity checkpoint GO:0044774 75 0.212
purine ribonucleoside catabolic process GO:0046130 112 0.208
regulation of cell cycle process GO:0010564 181 0.208
purine nucleoside metabolic process GO:0042278 127 0.208
meiotic cell cycle process GO:1903046 132 0.206
chromatin assembly or disassembly GO:0006333 52 0.203
ribonucleoside triphosphate metabolic process GO:0009199 119 0.197
rna processing GO:0006396 147 0.195
negative regulation of chromosome segregation GO:0051985 14 0.193
regulation of sister chromatid cohesion GO:0007063 2 0.189
regulation of mitotic sister chromatid segregation GO:0033047 28 0.188
protein catabolic process GO:0030163 101 0.187
response to biotic stimulus GO:0009607 294 0.186
metaphase anaphase transition of cell cycle GO:0044784 28 0.175
negative regulation of mitotic sister chromatid separation GO:2000816 13 0.172
dna recombination GO:0006310 32 0.172
ribonucleoprotein complex subunit organization GO:0071826 28 0.165
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.165
nucleoside triphosphate catabolic process GO:0009143 108 0.164
nucleoside catabolic process GO:0009164 112 0.163
positive regulation of rna biosynthetic process GO:1902680 266 0.162
Human Worm
muscle structure development GO:0061061 224 0.162
nucleosome mobilization GO:0042766 9 0.160
gene silencing by rna GO:0031047 57 0.158
Worm
protein alkylation GO:0008213 43 0.157
dna conformation change GO:0071103 105 0.151
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.151
cellular macromolecule catabolic process GO:0044265 136 0.151
cell motility GO:0048870 251 0.149
Zebrafish
embryonic pattern specification GO:0009880 174 0.142
localization of cell GO:0051674 257 0.141
Zebrafish
histone lysine methylation GO:0034968 32 0.140
positive regulation of cellular protein metabolic process GO:0032270 118 0.138
Human
mitotic sister chromatid separation GO:0051306 30 0.137
proteasomal protein catabolic process GO:0010498 59 0.136
dendrite morphogenesis GO:0048813 199 0.136
macromolecule catabolic process GO:0009057 161 0.132
negative regulation of rna metabolic process GO:0051253 251 0.132
mitotic cell cycle checkpoint GO:0007093 88 0.131
negative regulation of signal transduction GO:0009968 206 0.127
Human Mouse Worm
protein localization GO:0008104 284 0.126
ribonucleoside triphosphate catabolic process GO:0009203 108 0.121
nucleoside phosphate catabolic process GO:1901292 110 0.119
modification dependent macromolecule catabolic process GO:0043632 79 0.116
endocytosis GO:0006897 310 0.114
Worm
organonitrogen compound metabolic process GO:1901564 318 0.114
genitalia development GO:0048806 26 0.113
Worm
positive regulation of gene expression GO:0010628 290 0.113
Human Worm
mitotic spindle organization GO:0007052 220 0.113
dendrite development GO:0016358 204 0.112
organophosphate catabolic process GO:0046434 112 0.112
cell proliferation GO:0008283 299 0.111
Human Zebrafish Mouse
regulation of cellular catabolic process GO:0031329 157 0.109
regulation of programmed cell death GO:0043067 152 0.109
Mouse
ras protein signal transduction GO:0007265 88 0.109
Worm
posttranscriptional gene silencing GO:0016441 46 0.108
Worm
regulation of localization GO:0032879 275 0.107
peptidyl amino acid modification GO:0018193 105 0.106
carbohydrate derivative metabolic process GO:1901135 217 0.106
ribonucleoside metabolic process GO:0009119 127 0.105
eye photoreceptor cell differentiation GO:0001754 145 0.105
response to abiotic stimulus GO:0009628 341 0.104
cellular macromolecule localization GO:0070727 220 0.102
regulation of heterochromatin assembly GO:0031445 8 0.101
ribonucleoside monophosphate catabolic process GO:0009158 39 0.101
regulation of proteasomal protein catabolic process GO:0061136 39 0.101
nucleosome positioning GO:0016584 3 0.101
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.099
regulation of cell cycle GO:0051726 291 0.098
positive regulation of transcription dna templated GO:0045893 266 0.097
Human Worm
regulation of molecular function GO:0065009 217 0.096
Human Mouse
nucleoside monophosphate catabolic process GO:0009125 39 0.096
rna catabolic process GO:0006401 37 0.096
cell growth GO:0016049 108 0.094
regulation of multi organism process GO:0043900 131 0.094
Human
histone h4 k20 methylation GO:0034770 4 0.093
epithelial cell differentiation GO:0030855 322 0.091
Zebrafish Mouse
macromolecule methylation GO:0043414 45 0.090
dna repair GO:0006281 54 0.090
regulation of dna metabolic process GO:0051052 34 0.088
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.088
Human Worm
purine nucleotide metabolic process GO:0006163 146 0.087
nucleoside phosphate metabolic process GO:0006753 162 0.087
positive regulation of cell communication GO:0010647 250 0.085
ribonucleotide metabolic process GO:0009259 145 0.084
negative regulation of meiotic cell cycle GO:0051447 2 0.084
spindle organization GO:0007051 253 0.083
metaphase anaphase transition of mitotic cell cycle GO:0007091 28 0.083
purine nucleoside triphosphate metabolic process GO:0009144 119 0.082
regionalization GO:0003002 416 0.080
posttranscriptional gene silencing by rna GO:0035194 45 0.079
Worm
purine ribonucleotide metabolic process GO:0009150 145 0.078
purine ribonucleoside metabolic process GO:0046128 127 0.078
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.078
Human Worm
digestive tract development GO:0048565 149 0.077
Zebrafish Worm
histone methylation GO:0016571 40 0.077
chromosome separation GO:0051304 42 0.076
ribose phosphate metabolic process GO:0019693 145 0.076
regulation of protein metabolic process GO:0051246 256 0.075
Human Mouse
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.075
Zebrafish
multicellular organismal reproductive behavior GO:0033057 110 0.074
ribonucleoside catabolic process GO:0042454 112 0.074
response to radiation GO:0009314 155 0.071
anterior posterior pattern specification GO:0009952 136 0.069
Zebrafish
death GO:0016265 284 0.069
Mouse Worm
nucleobase containing small molecule metabolic process GO:0055086 174 0.069
axon guidance GO:0007411 233 0.069
regulation of organelle organization GO:0033043 196 0.068
Mouse
organelle assembly GO:0070925 198 0.067
Mouse
regulation of neurogenesis GO:0050767 158 0.067
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.066
compound eye photoreceptor cell differentiation GO:0001751 140 0.066
small gtpase mediated signal transduction GO:0007264 88 0.065
Worm
purine ribonucleoside monophosphate catabolic process GO:0009169 38 0.065
purine containing compound metabolic process GO:0072521 155 0.065
purine nucleoside monophosphate metabolic process GO:0009126 50 0.065
regulation of transcription by chromatin organization GO:0034401 3 0.064
regulation of cell differentiation GO:0045595 302 0.063
dna methylation GO:0006306 4 0.062
muscle cell differentiation GO:0042692 103 0.062
Mouse
protein complex assembly GO:0006461 200 0.061
cellular component disassembly GO:0022411 46 0.060
regulation of phosphorylation GO:0042325 147 0.060
ovarian follicle cell development GO:0030707 248 0.058
protein dna complex assembly GO:0065004 63 0.057
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.056
organonitrogen compound catabolic process GO:1901565 128 0.056
ribonucleoprotein complex biogenesis GO:0022613 31 0.055
axis specification GO:0009798 167 0.054
heterochromatin organization GO:0070828 25 0.053
oocyte development GO:0048599 124 0.053
protein complex disassembly GO:0043241 36 0.053
purine nucleotide catabolic process GO:0006195 109 0.052
regulation of apoptotic process GO:0042981 130 0.052
Mouse
intracellular transport GO:0046907 228 0.051
muscle organ development GO:0007517 127 0.050
circulatory system development GO:0072359 82 0.049
Mouse
regulation of cell development GO:0060284 215 0.049
regulation of nuclear division GO:0051783 58 0.048
ubiquitin dependent protein catabolic process GO:0006511 78 0.047
nucleocytoplasmic transport GO:0006913 72 0.047
phosphorylation GO:0016310 294 0.046
regulation of meiotic cell cycle GO:0051445 9 0.046
organophosphate metabolic process GO:0019637 195 0.046
multi multicellular organism process GO:0044706 123 0.045
covalent chromatin modification GO:0016569 106 0.044
cell migration GO:0016477 238 0.044
Zebrafish
proteolysis GO:0006508 192 0.044
Human
cellular component assembly involved in morphogenesis GO:0010927 151 0.043
Mouse
regulation of response to stress GO:0080134 200 0.043
mitotic cytokinesis GO:0000281 50 0.043
digestive tract morphogenesis GO:0048546 127 0.043
Worm
dna alkylation GO:0006305 4 0.042
regulation of ras protein signal transduction GO:0046578 93 0.042
Worm
ribonucleoside monophosphate metabolic process GO:0009161 51 0.042
mitotic chromosome condensation GO:0007076 22 0.042
positive regulation of intracellular signal transduction GO:1902533 116 0.041
negative regulation of catabolic process GO:0009895 36 0.041
regulation of cell division GO:0051302 72 0.040
tube morphogenesis GO:0035239 191 0.040
Worm
oviposition GO:0018991 19 0.040
regulation of proteolysis GO:0030162 87 0.039
Human
nucleoside metabolic process GO:0009116 127 0.039
negative regulation of proteasomal protein catabolic process GO:1901799 16 0.039
heterochromatin organization involved in chromatin silencing GO:0070868 9 0.038
eggshell formation GO:0030703 105 0.037
regulation of cellular response to stress GO:0080135 89 0.036
tendon development GO:0035989 1 0.036
regulation of chromosome segregation GO:0051983 32 0.036
positive regulation of proteolysis GO:0045862 52 0.035
Human
regulation of response to external stimulus GO:0032101 115 0.034
cellular response to hormone stimulus GO:0032870 44 0.034
oxoacid metabolic process GO:0043436 103 0.034
regulation of chromatin silencing GO:0031935 36 0.034
intracellular receptor signaling pathway GO:0030522 19 0.034
Human
cell division GO:0051301 248 0.034
segmentation GO:0035282 207 0.034
atp catabolic process GO:0006200 38 0.033
ribonucleoprotein complex assembly GO:0022618 23 0.033
cellular protein complex assembly GO:0043623 71 0.033
purine nucleoside monophosphate catabolic process GO:0009128 38 0.033
response to other organism GO:0051707 293 0.033
oocyte morphogenesis GO:0048601 3 0.032
brain development GO:0007420 120 0.032
Zebrafish Mouse
photoreceptor cell differentiation GO:0046530 170 0.031
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.031
cellular protein catabolic process GO:0044257 83 0.031
response to external biotic stimulus GO:0043207 293 0.030
establishment of protein localization GO:0045184 163 0.030
maternal determination of dorsal ventral axis ovarian follicular epithelium soma encoded GO:0008071 1 0.030
double strand break repair GO:0006302 26 0.030
regulation of dna templated transcription elongation GO:0032784 17 0.030
positive regulation of molecular function GO:0044093 136 0.030
Mouse
negative regulation of chromosome organization GO:2001251 19 0.029
positive regulation of signaling GO:0023056 243 0.029
dna templated transcription elongation GO:0006354 18 0.028
protein phosphorylation GO:0006468 169 0.028
spermatogenesis GO:0007283 200 0.028
protein transport GO:0015031 155 0.028
epithelial cell fate determination open tracheal system GO:0007425 2 0.028
dendrite regeneration GO:0031104 2 0.027
digestive system development GO:0055123 149 0.027
Zebrafish Worm
protein methylation GO:0006479 43 0.027
dna methylation or demethylation GO:0044728 4 0.027
positive regulation of programmed cell death GO:0043068 62 0.027
regulation of sister chromatid segregation GO:0033045 28 0.027
regulation of cellular protein catabolic process GO:1903362 44 0.027
embryonic axis specification GO:0000578 107 0.027
regulation of centriole replication GO:0046599 2 0.027
signal transduction by phosphorylation GO:0023014 107 0.027
cytokinesis GO:0000910 90 0.026
production of small rna involved in gene silencing by rna GO:0070918 15 0.025
regulation of catalytic activity GO:0050790 185 0.025
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 16 0.025
positive regulation of cellular catabolic process GO:0031331 95 0.025
eye morphogenesis GO:0048592 260 0.024
Zebrafish
regulation of defense response to virus by host GO:0050691 10 0.024
regulation of nervous system development GO:0051960 248 0.024
dendrite guidance GO:0070983 21 0.023
regulation of small gtpase mediated signal transduction GO:0051056 93 0.023
Worm
positive regulation of cellular biosynthetic process GO:0031328 316 0.023
Human Worm
camera type eye morphogenesis GO:0048593 2 0.023
Zebrafish
sister chromatid cohesion GO:0007062 18 0.023
oocyte construction GO:0007308 112 0.023
intrinsic apoptotic signaling pathway GO:0097193 16 0.022
Mouse
neurological system process GO:0050877 358 0.022
germarium derived egg chamber formation GO:0007293 101 0.022
response to red or far red light GO:0009639 2 0.022
mrna metabolic process GO:0016071 124 0.022
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.022
Human Worm
single organism behavior GO:0044708 391 0.022
nitrogen compound transport GO:0071705 85 0.021
regulation of protein serine threonine kinase activity GO:0071900 25 0.021
regulation of anatomical structure morphogenesis GO:0022603 242 0.021
spindle assembly involved in mitosis GO:0090307 50 0.021
determination of adult lifespan GO:0008340 137 0.021
organelle inheritance GO:0048308 2 0.021
programmed cell death GO:0012501 257 0.021
Mouse Worm
olfactory behavior GO:0042048 97 0.021
protein targeting to nucleus GO:0044744 51 0.020
positive regulation of apoptotic process GO:0043065 47 0.020
regulation of cell death GO:0010941 173 0.020
Mouse
regulation of phosphate metabolic process GO:0019220 210 0.020
regulation of planar cell polarity pathway involved in axis elongation GO:2000040 2 0.020
production of sirna involved in rna interference GO:0030422 11 0.020
stem cell differentiation GO:0048863 117 0.020
Zebrafish
sensory organ morphogenesis GO:0090596 260 0.020
Zebrafish Mouse
cellular protein localization GO:0034613 160 0.020
protein modification by small protein conjugation or removal GO:0070647 106 0.020
activation of ral gtpase activity GO:0032859 1 0.020
regulation of mitosis GO:0007088 56 0.020
reproductive behavior GO:0019098 122 0.020
positive regulation of biosynthetic process GO:0009891 316 0.020
Human Worm
single organism cellular localization GO:1902580 180 0.019
eye development GO:0001654 323 0.019
Zebrafish Mouse
developmental growth GO:0048589 280 0.019
Zebrafish Mouse
cuticle development GO:0042335 86 0.019
dorsal vessel heart proper cell fate commitment GO:0035053 2 0.019
positive regulation of cellular component organization GO:0051130 156 0.019
nuclear transport GO:0051169 72 0.019
positive regulation of signal transduction GO:0009967 223 0.019
meiotic nuclear envelope disassembly GO:0051078 2 0.018
nuclear dna replication GO:0033260 1 0.018
regulation of cell proliferation involved in compound eye morphogenesis GO:2000495 2 0.018
protein complex biogenesis GO:0070271 201 0.018
negative regulation of terminal cell fate specification open tracheal system GO:0035155 2 0.018
nucleoside monophosphate metabolic process GO:0009123 52 0.017
maintenance of chromatin silencing GO:0006344 0 0.017
Human
regulation of intracellular protein transport GO:0033157 46 0.017
mitochondrial membrane organization GO:0007006 3 0.017
oocyte fate commitment GO:0048600 2 0.017
compound eye development GO:0048749 307 0.017
eggshell chorion assembly GO:0007306 66 0.016
regulation of striated muscle contraction GO:0006942 2 0.016
formation of a compartment boundary GO:0060288 4 0.016
protein modification by small protein conjugation GO:0032446 79 0.016
cellular response to nutrient GO:0031670 1 0.016
mitotic spindle elongation GO:0000022 81 0.016
cellular amine metabolic process GO:0044106 12 0.016
regulation of nucleoside metabolic process GO:0009118 50 0.016
positive regulation of golgi to plasma membrane protein transport GO:0042998 2 0.016
glial cell fate determination GO:0007403 3 0.016
histone h2a acetylation GO:0043968 1 0.016
positive regulation of transport GO:0051050 92 0.016
centrosome organization GO:0051297 163 0.016
retina development in camera type eye GO:0060041 4 0.015
Zebrafish
eggshell chorion gene amplification GO:0007307 9 0.015
columnar cuboidal epithelial cell development GO:0002066 249 0.015
meiotic spindle checkpoint GO:0044779 1 0.015
humoral immune response GO:0006959 117 0.015
head development GO:0060322 135 0.015
Zebrafish Mouse
response to wounding GO:0009611 94 0.015
Zebrafish
nuclear export GO:0051168 24 0.014
regulation of nucleotide metabolic process GO:0006140 62 0.014
regulation of protein modification process GO:0031399 112 0.014
Mouse
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 30 0.014
maintenance of blood brain barrier GO:0035633 1 0.014
negative regulation of cellular catabolic process GO:0031330 34 0.014
regulation of phosphorus metabolic process GO:0051174 210 0.014
specification of segmental identity antennal segment GO:0007383 2 0.014
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.014
organic substance transport GO:0071702 257 0.014
anterior posterior axis specification GO:0009948 109 0.013
mapk cascade GO:0000165 107 0.013
defense response GO:0006952 300 0.013
border follicle cell delamination GO:0030709 3 0.013
establishment of rna localization GO:0051236 47 0.013
negative regulation of lamellocyte differentiation GO:0035204 5 0.013
regulation of gene silencing GO:0060968 63 0.013
nitric oxide metabolic process GO:0046209 1 0.013
chemosensory behavior GO:0007635 106 0.013
lipid localization GO:0010876 54 0.013
negative regulation of signaling GO:0023057 219 0.013
Human Mouse Worm
single organism intracellular transport GO:1902582 207 0.013
regulation of phosphatase activity GO:0010921 3 0.012
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.012
protein localization to nucleus GO:0034504 55 0.012
regulation of cellular localization GO:0060341 136 0.012
multi organism behavior GO:0051705 175 0.012
modification dependent protein catabolic process GO:0019941 78 0.012
protein import into nucleus GO:0006606 51 0.012
chitin based larval cuticle pattern formation GO:0035293 11 0.012
negative regulation of dna templated transcription initiation GO:2000143 1 0.012
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 15 0.012
Human
anterior posterior axis specification follicular epithelium GO:0030714 2 0.012
dna integration GO:0015074 1 0.012
gene silencing by mirna GO:0035195 22 0.012
dorsal closure leading edge cell differentiation GO:0046663 2 0.012
negative regulation of multicellular organismal process GO:0051241 142 0.012
nucleobase containing compound transport GO:0015931 56 0.012
response to heat GO:0009408 63 0.012
protein localization to organelle GO:0033365 82 0.012
negative regulation of organelle organization GO:0010639 56 0.011
regulation of cell size GO:0008361 63 0.011
cellular carbohydrate metabolic process GO:0044262 22 0.011
cytoskeleton dependent cytokinesis GO:0061640 81 0.011
positive regulation of ras protein signal transduction GO:0046579 43 0.011
maintenance of sister chromatid cohesion GO:0034086 1 0.011
negative regulation of neuroblast proliferation GO:0007406 27 0.011
cellularization GO:0007349 90 0.011
internal protein amino acid acetylation GO:0006475 38 0.011
regulation of cell shape GO:0008360 113 0.011
cell maturation GO:0048469 144 0.011
regulation of ran gtpase activity GO:0032316 1 0.011
regulation of protein localization GO:0032880 76 0.011
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.011
phagocytosis GO:0006909 215 0.011
regulation of rna export from nucleus GO:0046831 3 0.011
response to ionizing radiation GO:0010212 32 0.011
regulation of purine nucleotide metabolic process GO:1900542 62 0.011
septin ring organization GO:0031106 1 0.011
positive regulation of neuron projection regeneration GO:0070572 3 0.010
regulation of protein phosphorylation GO:0001932 64 0.010
positive regulation of heterochromatin assembly GO:0031453 5 0.010
multi organism reproductive behavior GO:0044705 121 0.010
negative regulation of nucleotide catabolic process GO:0030812 1 0.010
cellular response to nitrogen compound GO:1901699 51 0.010
positive regulation of chromatin silencing GO:0031937 16 0.010
regulation of endocrine process GO:0044060 2 0.010
positive regulation of catalytic activity GO:0043085 118 0.010
response to gamma radiation GO:0010332 17 0.010
male gamete generation GO:0048232 201 0.010

Rpd3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.040
disease of cellular proliferation DOID:14566 0 0.040
organ system cancer DOID:0050686 0 0.040
heart disease DOID:114 0 0.021
heart valve disease DOID:4079 0 0.021
disease of anatomical entity DOID:7 0 0.021
cardiovascular system disease DOID:1287 0 0.021
aortic valve disease DOID:62 0 0.021
thyroid carcinoma DOID:3963 0 0.014
endocrine gland cancer DOID:170 0 0.014
thyroid cancer DOID:1781 0 0.014
follicular thyroid carcinoma DOID:3962 0 0.014
tuberous sclerosis DOID:13515 0 0.012
aortic valve stenosis DOID:1712 0 0.010