Drosophila melanogaster

141 known processes

eIF4AIII (Dmel_CG7483)

CG7483 gene product from transcript CG7483-RA

(Aliases: CG7483,anon-WO0118547.364,eIF4A-III,Dmel\CG7483,l(3)84Fi,7483,DmRH28,eIF4A)

eIF4AIII biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna integrity checkpoint GO:0031570 81 0.774
cell cycle phase transition GO:0044770 140 0.727
mitotic cell cycle phase transition GO:0044772 138 0.716
dna damage checkpoint GO:0000077 78 0.673
spindle organization GO:0007051 253 0.669
nuclear division GO:0000280 332 0.659
Worm
mitotic spindle organization GO:0007052 220 0.640
negative regulation of cellular metabolic process GO:0031324 382 0.625
Human
mitotic g2 dna damage checkpoint GO:0007095 69 0.577
mitotic dna damage checkpoint GO:0044773 74 0.536
positive regulation of macromolecule metabolic process GO:0010604 405 0.473
Human Mouse
transcription from rna polymerase ii promoter GO:0006366 368 0.398
Mouse
positive regulation of gene expression GO:0010628 290 0.385
Human Mouse
positive regulation of rna metabolic process GO:0051254 271 0.372
Mouse
regulation of organelle organization GO:0033043 196 0.360
Worm
death GO:0016265 284 0.359
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.356
Human Mouse
cell death GO:0008219 279 0.344
mitotic dna integrity checkpoint GO:0044774 75 0.340
organelle fission GO:0048285 340 0.333
Worm
regulation of mitotic cell cycle phase transition GO:1901990 130 0.321
positive regulation of nucleic acid templated transcription GO:1903508 266 0.308
Mouse
cellular response to dna damage stimulus GO:0006974 223 0.298
g2 dna damage checkpoint GO:0031572 69 0.290
positive regulation of rna biosynthetic process GO:1902680 266 0.289
Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.278
Mouse
macromolecular complex assembly GO:0065003 256 0.266
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.264
Mouse
regulation of cell cycle GO:0051726 291 0.263
Worm
mitotic cell cycle checkpoint GO:0007093 88 0.258
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.237
Mouse
regulation of localization GO:0032879 275 0.231
rna processing GO:0006396 147 0.230
negative regulation of cell cycle phase transition GO:1901988 103 0.225
chromatin organization GO:0006325 207 0.210
regulation of rna splicing GO:0043484 69 0.203
Mouse
organelle assembly GO:0070925 198 0.203
negative regulation of cell cycle process GO:0010948 109 0.202
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.182
positive regulation of cellular biosynthetic process GO:0031328 316 0.179
Human Mouse
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.176
Mouse
negative regulation of mitotic cell cycle GO:0045930 109 0.176
regulation of cell cycle phase transition GO:1901987 130 0.175
programmed cell death GO:0012501 257 0.171
cellular macromolecular complex assembly GO:0034622 153 0.169
regulation of mitotic cell cycle GO:0007346 190 0.168
regulation of cell cycle process GO:0010564 181 0.167
Worm
regulation of phosphate metabolic process GO:0019220 210 0.165
apoptotic process GO:0006915 159 0.165
negative regulation of cell cycle GO:0045786 116 0.163
positive regulation of response to stimulus GO:0048584 323 0.160
mitotic g2 m transition checkpoint GO:0044818 70 0.157
embryo development ending in birth or egg hatching GO:0009792 152 0.157
Human Worm
protein modification process GO:0036211 438 0.154
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.153
Human
endocytosis GO:0006897 310 0.134
establishment of localization in cell GO:0051649 402 0.134
negative regulation of signaling GO:0023057 219 0.130
negative regulation of rna metabolic process GO:0051253 251 0.129
vesicle mediated transport GO:0016192 381 0.128
regulation of apoptotic process GO:0042981 130 0.123
cell proliferation GO:0008283 299 0.118
Worm
intracellular transport GO:0046907 228 0.115
positive regulation of biosynthetic process GO:0009891 316 0.112
Human Mouse
regulation of phosphorus metabolic process GO:0051174 210 0.109
chromatin modification GO:0016568 147 0.105
phosphorylation GO:0016310 294 0.104
regulation of cell death GO:0010941 173 0.104
regulation of protein metabolic process GO:0051246 256 0.101
Human
positive regulation of cellular component organization GO:0051130 156 0.100
actin cytoskeleton organization GO:0030036 206 0.098
regulation of programmed cell death GO:0043067 152 0.096
negative regulation of gene expression GO:0010629 387 0.094
Human
epithelial cell differentiation GO:0030855 322 0.094
regulation of mapk cascade GO:0043408 92 0.092
rna localization GO:0006403 115 0.090
germarium derived egg chamber formation GO:0007293 101 0.084
protein complex biogenesis GO:0070271 201 0.084
establishment of organelle localization GO:0051656 122 0.083
embryonic pattern specification GO:0009880 174 0.080
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.080
cellular protein modification process GO:0006464 438 0.079
regulation of gene expression epigenetic GO:0040029 128 0.078
regulation of cellular protein metabolic process GO:0032268 243 0.077
Human
segmentation GO:0035282 207 0.072
regulation of cellular component biogenesis GO:0044087 201 0.071
negative regulation of transcription dna templated GO:0045892 237 0.069
regulation of anatomical structure morphogenesis GO:0022603 242 0.069
gene silencing GO:0016458 138 0.068
protein dna complex assembly GO:0065004 63 0.067
positive regulation of transcription dna templated GO:0045893 266 0.066
Mouse
dephosphorylation GO:0016311 51 0.065
meiotic nuclear division GO:0007126 151 0.065
Worm
positive regulation of protein metabolic process GO:0051247 128 0.064
Human
negative regulation of cell communication GO:0010648 223 0.064
negative regulation of response to stimulus GO:0048585 258 0.064
regulation of hydrolase activity GO:0051336 97 0.063
positive regulation of cellular protein metabolic process GO:0032270 118 0.062
Human
cellular component assembly involved in morphogenesis GO:0010927 151 0.062
glycosyl compound catabolic process GO:1901658 112 0.062
Human
neurological system process GO:0050877 358 0.062
chromosome organization GO:0051276 360 0.061
carbohydrate derivative metabolic process GO:1901135 217 0.060
Human
alternative mrna splicing via spliceosome GO:0000380 60 0.059
regulation of cellular amino acid metabolic process GO:0006521 0 0.057
regulation of cell division GO:0051302 72 0.057
Worm
negative regulation of protein metabolic process GO:0051248 85 0.056
Human
posttranscriptional regulation of gene expression GO:0010608 145 0.056
Human
intracellular signal transduction GO:0035556 300 0.054
single organism catabolic process GO:0044712 228 0.054
Human
regulation of response to stress GO:0080134 200 0.053
negative regulation of cellular biosynthetic process GO:0031327 277 0.053
Human
single organism behavior GO:0044708 391 0.053
nitrogen compound transport GO:0071705 85 0.053
negative regulation of gene expression epigenetic GO:0045814 77 0.052
camera type eye development GO:0043010 4 0.052
positive regulation of phosphate metabolic process GO:0045937 139 0.051
rna transport GO:0050658 46 0.050
positive regulation of catalytic activity GO:0043085 118 0.050
negative regulation of biosynthetic process GO:0009890 277 0.050
Human
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.050
positive regulation of molecular function GO:0044093 136 0.047
negative regulation of nucleic acid templated transcription GO:1903507 240 0.047
regulation of catalytic activity GO:0050790 185 0.047
positive regulation of intracellular signal transduction GO:1902533 116 0.045
organonitrogen compound metabolic process GO:1901564 318 0.045
Human
regulation of transport GO:0051049 181 0.044
regulation of meiosis GO:0040020 3 0.042
Worm
regulation of phosphorylation GO:0042325 147 0.042
sex differentiation GO:0007548 81 0.042
Worm
regionalization GO:0003002 416 0.042
ribonucleoside triphosphate catabolic process GO:0009203 108 0.042
Human
blastoderm segmentation GO:0007350 159 0.040
regulation of cell morphogenesis GO:0022604 163 0.040
reproductive structure development GO:0048608 74 0.040
Worm
establishment of rna localization GO:0051236 47 0.038
regulation of molecular function GO:0065009 217 0.038
cellular response to chemical stimulus GO:0070887 199 0.036
negative regulation of cellular protein metabolic process GO:0032269 85 0.036
Human
positive regulation of cell communication GO:0010647 250 0.035
nucleoside triphosphate catabolic process GO:0009143 108 0.035
Human
cell cycle checkpoint GO:0000075 95 0.035
positive regulation of phosphorus metabolic process GO:0010562 139 0.035
retina development in camera type eye GO:0060041 4 0.035
mapk cascade GO:0000165 107 0.035
negative regulation of rna biosynthetic process GO:1902679 240 0.034
negative regulation of cellular component organization GO:0051129 108 0.034
taxis GO:0042330 304 0.034
growth GO:0040007 359 0.034
g1 s transition of mitotic cell cycle GO:0000082 31 0.033
response to abiotic stimulus GO:0009628 341 0.033
negative regulation of developmental pigmentation GO:0048086 1 0.033
positive regulation of signaling GO:0023056 243 0.032
positive regulation of phosphorylation GO:0042327 87 0.032
genitalia development GO:0048806 26 0.031
Worm
regulation of mrna metabolic process GO:1903311 72 0.031
Mouse
regulation of cell proliferation GO:0042127 163 0.031
Worm
nucleotide catabolic process GO:0009166 109 0.031
Human
small gtpase mediated signal transduction GO:0007264 88 0.029
response to organic substance GO:0010033 284 0.029
regulation of protein modification process GO:0031399 112 0.029
body morphogenesis GO:0010171 2 0.029
regulation of proteolysis GO:0030162 87 0.029
nucleotide metabolic process GO:0009117 161 0.029
Human
regulation of multicellular organismal development GO:2000026 414 0.028
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.028
Human
organophosphate metabolic process GO:0019637 195 0.028
Human
ras protein signal transduction GO:0007265 88 0.028
cellular response to organic substance GO:0071310 132 0.028
organophosphate catabolic process GO:0046434 112 0.028
Human
regulation of immune system process GO:0002682 176 0.028
positive regulation of signal transduction GO:0009967 223 0.028
photoreceptor cell differentiation GO:0046530 170 0.027
proteasomal protein catabolic process GO:0010498 59 0.027
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.027
actin filament based process GO:0030029 220 0.027
purine nucleotide metabolic process GO:0006163 146 0.026
Human
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.026
Human
mrna transport GO:0051028 15 0.026
protein dna complex subunit organization GO:0071824 86 0.026
regulation of cellular amine metabolic process GO:0033238 3 0.025
ribonucleoprotein complex biogenesis GO:0022613 31 0.025
Yeast
spindle assembly GO:0051225 80 0.025
eye development GO:0001654 323 0.025
regulation of cell shape GO:0008360 113 0.025
regulation of cell differentiation GO:0045595 302 0.025
larval development GO:0002164 104 0.025
Worm
ribonucleotide metabolic process GO:0009259 145 0.025
Human
gonad development GO:0008406 50 0.025
Worm
regulation of mrna processing GO:0050684 71 0.025
Mouse
purine nucleoside metabolic process GO:0042278 127 0.024
Human
ribose phosphate metabolic process GO:0019693 145 0.024
Human
signal transduction by phosphorylation GO:0023014 107 0.023
peptidyl serine phosphorylation GO:0018105 7 0.023
cell motility GO:0048870 251 0.023
microtubule organizing center organization GO:0031023 168 0.022
cellular component disassembly GO:0022411 46 0.022
positive regulation of mapk cascade GO:0043410 63 0.022
chemotaxis GO:0006935 249 0.022
single organism intracellular transport GO:1902582 207 0.022
transcription elongation from rna polymerase ii promoter GO:0006368 18 0.022
purine ribonucleotide metabolic process GO:0009150 145 0.021
Human
positive regulation of cell death GO:0010942 69 0.021
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.021
regulation of intracellular signal transduction GO:1902531 236 0.021
reproductive system development GO:0061458 74 0.020
Worm
regulation of cellular ketone metabolic process GO:0010565 3 0.019
localization of cell GO:0051674 257 0.019
cell chemotaxis involved in malpighian tubule morphogenesis GO:0061352 3 0.019
salivary gland development GO:0007431 162 0.019
sensory organ morphogenesis GO:0090596 260 0.019
regulation of cellular response to stress GO:0080135 89 0.019
cytoplasmic transport GO:0016482 130 0.019
unsaturated fatty acid biosynthetic process GO:0006636 1 0.019
cellular amino acid metabolic process GO:0006520 61 0.019
chromatin silencing GO:0006342 76 0.019
purine nucleoside catabolic process GO:0006152 112 0.018
Human
mitotic spindle elongation GO:0000022 81 0.018
nucleobase containing compound transport GO:0015931 56 0.018
organelle inheritance GO:0048308 2 0.018
positive regulation of hydrolase activity GO:0051345 78 0.018
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.018
regulation of response to external stimulus GO:0032101 115 0.018
proteolysis GO:0006508 192 0.018
cellular ketone metabolic process GO:0042180 24 0.018
single organism cellular localization GO:1902580 180 0.017
mrna processing GO:0006397 104 0.017
Mouse
multi organism behavior GO:0051705 175 0.017
Worm
response to biotic stimulus GO:0009607 294 0.017
organelle localization GO:0051640 148 0.017
cell cycle g1 s phase transition GO:0044843 31 0.017
histone modification GO:0016570 106 0.016
activation of cysteine type endopeptidase activity GO:0097202 17 0.016
ribonucleoside metabolic process GO:0009119 127 0.016
Human
amine metabolic process GO:0009308 12 0.016
protein acylation GO:0043543 42 0.016
protein modification by small protein conjugation GO:0032446 79 0.015
cellular response to nutrient GO:0031670 1 0.015
development of primary sexual characteristics GO:0045137 50 0.015
Worm
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.015
Human
regulation of small gtpase mediated signal transduction GO:0051056 93 0.015
organic substance catabolic process GO:1901575 308 0.015
Human
macromolecule catabolic process GO:0009057 161 0.015
Human
carbohydrate derivative catabolic process GO:1901136 118 0.015
Human
meiotic cell cycle GO:0051321 171 0.015
Worm
chromatin remodeling GO:0006338 72 0.015
protein catabolic process GO:0030163 101 0.015
protein complex assembly GO:0006461 200 0.015
stem cell differentiation GO:0048863 117 0.015
response to oxygen containing compound GO:1901700 200 0.014
immune system process GO:0002376 347 0.014
left right axis specification GO:0070986 1 0.014
covalent chromatin modification GO:0016569 106 0.014
receptor mediated endocytosis GO:0006898 21 0.014
regulation of transferase activity GO:0051338 58 0.014
response to external biotic stimulus GO:0043207 293 0.013
aromatic compound catabolic process GO:0019439 166 0.013
Human
purine containing compound metabolic process GO:0072521 155 0.013
Human
cellular homeostasis GO:0019725 80 0.013
erk1 and erk2 cascade GO:0070371 39 0.013
regulation of mrna splicing via spliceosome GO:0048024 64 0.013
Mouse
nucleocytoplasmic transport GO:0006913 72 0.013
nucleosome organization GO:0034728 59 0.013
regulation of translation GO:0006417 56 0.013
Human
regulation of nuclear division GO:0051783 58 0.013
Worm
phagocytosis GO:0006909 215 0.013
intermediate filament based process GO:0045103 1 0.013
developmental maturation GO:0021700 172 0.012
positive regulation of apoptotic process GO:0043065 47 0.012
developmental growth GO:0048589 280 0.012
eye photoreceptor cell differentiation GO:0001754 145 0.012
spindle assembly involved in mitosis GO:0090307 50 0.012
dna conformation change GO:0071103 105 0.012
positive regulation of multicellular organismal process GO:0051240 143 0.012
organic cyclic compound catabolic process GO:1901361 168 0.012
Human
notch signaling pathway GO:0007219 120 0.012
regulation of cellular catabolic process GO:0031329 157 0.012
positive regulation of immune system process GO:0002684 68 0.012
positive regulation of cellular component biogenesis GO:0044089 80 0.011
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.011
nucleoside triphosphate metabolic process GO:0009141 120 0.011
Human
response to other organism GO:0051707 293 0.011
ribonucleoside triphosphate metabolic process GO:0009199 119 0.011
Human
organonitrogen compound catabolic process GO:1901565 128 0.011
Human
rrna processing GO:0006364 3 0.011
Yeast
regulation of cellular localization GO:0060341 136 0.011
protein ubiquitination GO:0016567 70 0.011
multi organism reproductive behavior GO:0044705 121 0.011
Worm
nucleic acid transport GO:0050657 46 0.011
protein destabilization GO:0031648 2 0.011
dna templated transcription elongation GO:0006354 18 0.011
mrna metabolic process GO:0016071 124 0.011
Human Mouse
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 1 0.011
mrna cis splicing via spliceosome GO:0045292 1 0.011
salivary gland morphogenesis GO:0007435 145 0.011
purine nucleoside triphosphate metabolic process GO:0009144 119 0.010
Human
positive regulation of erk1 and erk2 cascade GO:0070374 36 0.010
compound eye development GO:0048749 307 0.010
mitotic sister chromatid segregation GO:0000070 87 0.010
cell migration GO:0016477 238 0.010
organic substance transport GO:0071702 257 0.010
dorsal ventral pattern formation GO:0009953 133 0.010

eIF4AIII disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.024