Drosophila melanogaster

66 known processes

Uba2 (Dmel_CG7528)

Smt3 activating enzyme 2

(Aliases: sip2,uba2,CG7528,DmSAE2,Sae2,Ubc2,DmUba2,dUba2,L36,SAE2,UBA2,DmSae2,Dmuba2,Dmel\CG7528)

Uba2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of cellular metabolic process GO:0031324 382 0.938
negative regulation of transcription dna templated GO:0045892 237 0.850
establishment of localization in cell GO:0051649 402 0.675
negative regulation of biosynthetic process GO:0009890 277 0.597
negative regulation of nucleic acid templated transcription GO:1903507 240 0.489
chromosome organization GO:0051276 360 0.405
cell proliferation GO:0008283 299 0.343
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.335
regulation of phosphate metabolic process GO:0019220 210 0.331
cellular protein modification process GO:0006464 438 0.323
ecdysone mediated induction of salivary gland cell autophagic cell death GO:0035072 12 0.305
endocytosis GO:0006897 310 0.290
programmed cell death GO:0012501 257 0.281
induction of programmed cell death by ecdysone GO:0035078 12 0.275
induction of programmed cell death GO:0012502 12 0.253
eye development GO:0001654 323 0.252
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.242
negative regulation of cellular biosynthetic process GO:0031327 277 0.240
negative regulation of response to stimulus GO:0048585 258 0.224
eye morphogenesis GO:0048592 260 0.222
induction of programmed cell death by hormones GO:0035081 12 0.215
regulation of apoptotic process GO:0042981 130 0.206
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.189
negative regulation of catalytic activity GO:0043086 42 0.173
regulation of response to stress GO:0080134 200 0.173
retina morphogenesis in camera type eye GO:0060042 2 0.160
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.159
nucleobase containing small molecule metabolic process GO:0055086 174 0.154
negative regulation of cellular protein metabolic process GO:0032269 85 0.149
organic substance catabolic process GO:1901575 308 0.145
intracellular transport GO:0046907 228 0.142
regulation of catalytic activity GO:0050790 185 0.131
negative regulation of gene expression GO:0010629 387 0.124
regulation of mitotic cell cycle phase transition GO:1901990 130 0.123
positive regulation of response to stimulus GO:0048584 323 0.116
glycosyl compound catabolic process GO:1901658 112 0.109
nucleoside phosphate catabolic process GO:1901292 110 0.104
regulation of catabolic process GO:0009894 170 0.101
cellular response to dna damage stimulus GO:0006974 223 0.101
regulation of cell proliferation GO:0042127 163 0.099
nucleotide metabolic process GO:0009117 161 0.098
death GO:0016265 284 0.094
peptidyl amino acid modification GO:0018193 105 0.092
tube morphogenesis GO:0035239 191 0.091
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.089
regulation of cell death GO:0010941 173 0.088
immune response GO:0006955 246 0.083
cell cycle phase transition GO:0044770 140 0.081
regulation of gene expression epigenetic GO:0040029 128 0.075
purine ribonucleoside catabolic process GO:0046130 112 0.074
mitotic sister chromatid cohesion GO:0007064 6 0.074
immune system process GO:0002376 347 0.073
protein modification process GO:0036211 438 0.071
regulation of hydrolase activity GO:0051336 97 0.070
regulation of erbb signaling pathway GO:1901184 42 0.070
stem cell differentiation GO:0048863 117 0.069
positive regulation of biosynthetic process GO:0009891 316 0.067
small molecule metabolic process GO:0044281 305 0.067
proteolysis GO:0006508 192 0.067
negative regulation of signal transduction GO:0009968 206 0.067
negative regulation of rna biosynthetic process GO:1902679 240 0.067
chromatin organization GO:0006325 207 0.065
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.065
compound eye development GO:0048749 307 0.064
single organism catabolic process GO:0044712 228 0.064
regulation of programmed cell death GO:0043067 152 0.064
epidermal growth factor receptor signaling pathway GO:0007173 58 0.064
regulation of molecular function GO:0065009 217 0.063
cell death GO:0008219 279 0.062
camera type eye morphogenesis GO:0048593 2 0.061
chromatin modification GO:0016568 147 0.061
innate immune response GO:0045087 144 0.060
purine ribonucleotide metabolic process GO:0009150 145 0.059
vesicle mediated transport GO:0016192 381 0.057
sister chromatid segregation GO:0000819 92 0.055
ribonucleoside triphosphate catabolic process GO:0009203 108 0.053
regulation of cellular catabolic process GO:0031329 157 0.052
regulation of phosphorylation GO:0042325 147 0.050
nucleoside triphosphate metabolic process GO:0009141 120 0.048
response to bacterium GO:0009617 198 0.048
compound eye morphogenesis GO:0001745 249 0.047
negative regulation of cell death GO:0060548 81 0.047
phosphorylation GO:0016310 294 0.046
regulation of phosphorus metabolic process GO:0051174 210 0.046
negative regulation of signaling GO:0023057 219 0.046
organelle assembly GO:0070925 198 0.045
nucleoside catabolic process GO:0009164 112 0.044
regulation of cell cycle phase transition GO:1901987 130 0.044
nucleoside triphosphate catabolic process GO:0009143 108 0.043
organonitrogen compound metabolic process GO:1901564 318 0.042
single organism nuclear import GO:1902593 51 0.041
negative regulation of protein metabolic process GO:0051248 85 0.041
larval development GO:0002164 104 0.041
defense response to other organism GO:0098542 225 0.041
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.039
regulation of dna metabolic process GO:0051052 34 0.039
purine nucleoside triphosphate metabolic process GO:0009144 119 0.038
germ line cyst formation GO:0048134 44 0.038
negative regulation of cell development GO:0010721 62 0.038
phagocytosis GO:0006909 215 0.036
retinal cone cell differentiation GO:0042670 2 0.035
negative regulation of rna metabolic process GO:0051253 251 0.035
zymogen activation GO:0031638 20 0.034
neuron apoptotic process GO:0051402 17 0.034
ribonucleoside triphosphate metabolic process GO:0009199 119 0.034
aging GO:0007568 143 0.033
positive regulation of transcription dna templated GO:0045893 266 0.033
protein phosphorylation GO:0006468 169 0.033
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 16 0.033
cell cycle checkpoint GO:0000075 95 0.032
regulation of cell cycle process GO:0010564 181 0.032
negative regulation of molecular function GO:0044092 51 0.032
ribonucleotide metabolic process GO:0009259 145 0.031
response to alcohol GO:0097305 95 0.031
nucleotide catabolic process GO:0009166 109 0.031
protein processing GO:0016485 68 0.030
carbohydrate derivative catabolic process GO:1901136 118 0.030
response to external biotic stimulus GO:0043207 293 0.030
regulation of meiosis GO:0040020 3 0.030
regulation of protein metabolic process GO:0051246 256 0.030
translation GO:0006412 69 0.030
catabolic process GO:0009056 409 0.030
regulation of mitotic sister chromatid segregation GO:0033047 28 0.029
negative regulation of phosphorylation GO:0042326 35 0.029
carbohydrate derivative metabolic process GO:1901135 217 0.028
purine ribonucleoside metabolic process GO:0046128 127 0.028
female germ line cyst formation GO:0048135 42 0.028
dna metabolic process GO:0006259 227 0.028
negative regulation of cell cycle phase transition GO:1901988 103 0.028
germarium derived female germ line cyst formation GO:0030727 42 0.027
ribose phosphate metabolic process GO:0019693 145 0.027
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.027
purine nucleoside triphosphate catabolic process GO:0009146 108 0.027
nucleoside phosphate metabolic process GO:0006753 162 0.027
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.025
single organism intracellular transport GO:1902582 207 0.025
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress GO:0070059 4 0.025
response to temperature stimulus GO:0009266 106 0.025
positive regulation of defense response to bacterium GO:1900426 23 0.024
regulation of chromatin modification GO:1903308 28 0.024
protein maturation GO:0051604 71 0.024
purine containing compound metabolic process GO:0072521 155 0.024
ribonucleotide catabolic process GO:0009261 109 0.024
negative regulation of phosphorus metabolic process GO:0010563 45 0.024
purine nucleotide metabolic process GO:0006163 146 0.023
dna replication GO:0006260 48 0.023
wnt signaling pathway GO:0016055 98 0.023
purine containing compound catabolic process GO:0072523 112 0.023
mitotic nuclear division GO:0007067 213 0.023
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.023
atp metabolic process GO:0046034 49 0.023
erbb signaling pathway GO:0038127 58 0.023
mitotic sister chromatid separation GO:0051306 30 0.022
mrna metabolic process GO:0016071 124 0.022
regulation of defense response GO:0031347 102 0.022
nuclear division GO:0000280 332 0.022
organelle localization GO:0051640 148 0.022
negative regulation of cell differentiation GO:0045596 143 0.022
purine nucleoside catabolic process GO:0006152 112 0.022
purine nucleotide catabolic process GO:0006195 109 0.022
regulation of cell cycle GO:0051726 291 0.021
retina development in camera type eye GO:0060041 4 0.021
neural retina development GO:0003407 4 0.021
regulation of proteolysis GO:0030162 87 0.021
homeostatic process GO:0042592 199 0.021
sensory organ morphogenesis GO:0090596 260 0.021
regulation of immune response GO:0050776 118 0.021
negative regulation of apoptotic process GO:0043066 63 0.021
regulation of mitotic cell cycle GO:0007346 190 0.020
nucleoside monophosphate metabolic process GO:0009123 52 0.020
gene silencing GO:0016458 138 0.020
cell cycle g2 m phase transition GO:0044839 22 0.020
negative regulation of cell cycle process GO:0010948 109 0.020
protein localization GO:0008104 284 0.020
appendage development GO:0048736 401 0.020
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.019
cellular catabolic process GO:0044248 372 0.019
regulation of cell differentiation GO:0045595 302 0.019
positive regulation of cell communication GO:0010647 250 0.019
positive regulation of gene expression GO:0010628 290 0.019
negative regulation of programmed cell death GO:0043069 72 0.019
tissue morphogenesis GO:0048729 297 0.019
regulation of cell development GO:0060284 215 0.018
heart development GO:0007507 82 0.018
ribonucleoside catabolic process GO:0042454 112 0.018
oxoacid metabolic process GO:0043436 103 0.018
purine ribonucleotide catabolic process GO:0009154 109 0.018
positive regulation of nucleotide metabolic process GO:0045981 55 0.018
regulation of innate immune response GO:0045088 71 0.018
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.017
single organism biosynthetic process GO:0044711 206 0.017
negative regulation of phosphate metabolic process GO:0045936 45 0.017
apoptotic process GO:0006915 159 0.017
regulation of autophagy GO:0010506 62 0.017
mitotic cell cycle phase transition GO:0044772 138 0.017
positive regulation of signaling GO:0023056 243 0.017
organophosphate metabolic process GO:0019637 195 0.017
mitotic sister chromatid segregation GO:0000070 87 0.017
regulation of cellular protein metabolic process GO:0032268 243 0.017
negative regulation of cell communication GO:0010648 223 0.017
regulation of gtp catabolic process GO:0033124 44 0.017
response to organic substance GO:0010033 284 0.016
embryonic organ development GO:0048568 50 0.016
response to starvation GO:0042594 97 0.016
cell growth GO:0016049 108 0.015
regulation of sister chromatid segregation GO:0033045 28 0.015
embryo development ending in birth or egg hatching GO:0009792 152 0.015
glycosyl compound metabolic process GO:1901657 127 0.015
metaphase anaphase transition of cell cycle GO:0044784 28 0.015
negative regulation of cell cycle GO:0045786 116 0.015
regulation of mitotic sister chromatid separation GO:0010965 28 0.015
positive regulation of intracellular signal transduction GO:1902533 116 0.015
reproductive structure development GO:0048608 74 0.015
transcription from rna polymerase ii promoter GO:0006366 368 0.015
defense response to gram negative bacterium GO:0050829 94 0.015
regulation of cell division GO:0051302 72 0.015
negative regulation of gene expression epigenetic GO:0045814 77 0.015
rna processing GO:0006396 147 0.014
defense response to bacterium GO:0042742 178 0.014
response to extracellular stimulus GO:0009991 116 0.014
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.014
regulation of multi organism process GO:0043900 131 0.014
nucleocytoplasmic transport GO:0006913 72 0.014
negative regulation of protein processing GO:0010955 31 0.014
response to sterol GO:0036314 34 0.014
ribonucleoside metabolic process GO:0009119 127 0.014
gtp catabolic process GO:0006184 72 0.013
negative regulation of developmental process GO:0051093 201 0.013
intracellular signal transduction GO:0035556 300 0.013
endomembrane system organization GO:0010256 119 0.013
mitotic spindle organization GO:0007052 220 0.013
metaphase anaphase transition of mitotic cell cycle GO:0007091 28 0.013
chromatin silencing GO:0006342 76 0.013
organelle membrane fusion GO:0090174 16 0.013
positive regulation of protein modification process GO:0031401 58 0.012
morphogenesis of a branching epithelium GO:0061138 45 0.012
protein catabolic process GO:0030163 101 0.012
nucleoside metabolic process GO:0009116 127 0.012
posttranscriptional gene silencing GO:0016441 46 0.012
carboxylic acid metabolic process GO:0019752 92 0.012
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.012
neuron maturation GO:0042551 31 0.012
response to ecdysone GO:0035075 34 0.012
anatomical structure homeostasis GO:0060249 97 0.012
nuclear export GO:0051168 24 0.012
regulation of immune system process GO:0002682 176 0.012
positive regulation of signal transduction GO:0009967 223 0.012
regulation of nucleotide catabolic process GO:0030811 48 0.011
reproductive system development GO:0061458 74 0.011
positive regulation of molecular function GO:0044093 136 0.011
purine nucleoside metabolic process GO:0042278 127 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.011
positive regulation of cellular biosynthetic process GO:0031328 316 0.011
organonitrogen compound catabolic process GO:1901565 128 0.011
cellular macromolecular complex assembly GO:0034622 153 0.011
regulation of organelle organization GO:0033043 196 0.011
negative regulation of endopeptidase activity GO:0010951 11 0.010
regulation of peptidase activity GO:0052547 39 0.010
regulation of nucleotide metabolic process GO:0006140 62 0.010
membrane organization GO:0061024 112 0.010
negative regulation of proteolysis GO:0045861 31 0.010
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.010
positive regulation of catalytic activity GO:0043085 118 0.010
nucleoside monophosphate catabolic process GO:0009125 39 0.010
cell junction assembly GO:0034329 42 0.010
organelle fission GO:0048285 340 0.010

Uba2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.011