Drosophila melanogaster

139 known processes

Bub3 (Dmel_CG7581)

CG7581 gene product from transcript CG7581-RA

(Aliases: bub3,dBUB3,CG7581,Dmel\CG7581,Dmbub3)

Bub3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chromosome organization GO:0051276 360 0.442
protein dna complex subunit organization GO:0071824 86 0.286
positive regulation of biosynthetic process GO:0009891 316 0.216
embryo development ending in birth or egg hatching GO:0009792 152 0.180
Worm
lateral inhibition GO:0046331 206 0.177
chromatin remodeling GO:0006338 72 0.173
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.167
negative regulation of cell cycle process GO:0010948 109 0.157
positive regulation of cellular biosynthetic process GO:0031328 316 0.141
positive regulation of gene expression GO:0010628 290 0.140
dna conformation change GO:0071103 105 0.127
positive regulation of nucleic acid templated transcription GO:1903508 266 0.126
positive regulation of transcription dna templated GO:0045893 266 0.126
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.120
negative regulation of gene expression GO:0010629 387 0.120
cell division GO:0051301 248 0.115
cellular catabolic process GO:0044248 372 0.104
cellular response to chemical stimulus GO:0070887 199 0.102
chromosome segregation GO:0007059 157 0.101
chromatin organization GO:0006325 207 0.097
chromatin modification GO:0016568 147 0.097
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.095
positive regulation of macromolecule metabolic process GO:0010604 405 0.092
positive regulation of rna biosynthetic process GO:1902680 266 0.091
chromatin assembly or disassembly GO:0006333 52 0.090
nucleocytoplasmic transport GO:0006913 72 0.085
negative regulation of response to stimulus GO:0048585 258 0.083
positive regulation of rna metabolic process GO:0051254 271 0.082
organic substance transport GO:0071702 257 0.080
transcription from rna polymerase ii promoter GO:0006366 368 0.078
chromatin assembly GO:0031497 48 0.078
nuclear transport GO:0051169 72 0.075
cell cycle phase transition GO:0044770 140 0.066
protein modification process GO:0036211 438 0.066
establishment of localization in cell GO:0051649 402 0.063
cellular amine metabolic process GO:0044106 12 0.063
posttranscriptional regulation of gene expression GO:0010608 145 0.062
nucleosome organization GO:0034728 59 0.061
single organism behavior GO:0044708 391 0.061
cytoplasmic transport GO:0016482 130 0.061
dna metabolic process GO:0006259 227 0.060
organonitrogen compound metabolic process GO:1901564 318 0.058
nucleosome assembly GO:0006334 35 0.058
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.057
nuclear division GO:0000280 332 0.056
mitotic cell cycle phase transition GO:0044772 138 0.055
cell proliferation GO:0008283 299 0.054
meiotic nuclear division GO:0007126 151 0.054
death GO:0016265 284 0.052
mitotic cell cycle checkpoint GO:0007093 88 0.052
cell death GO:0008219 279 0.051
eye development GO:0001654 323 0.050
regulation of cellular ketone metabolic process GO:0010565 3 0.050
regulation of cell death GO:0010941 173 0.049
small molecule metabolic process GO:0044281 305 0.049
positive regulation of cellular component biogenesis GO:0044089 80 0.047
protein dna complex assembly GO:0065004 63 0.046
intracellular transport GO:0046907 228 0.046
positive regulation of cell communication GO:0010647 250 0.044
regulation of organelle organization GO:0033043 196 0.043
regulation of cellular localization GO:0060341 136 0.043
regulation of mitotic cell cycle phase transition GO:1901990 130 0.043
negative regulation of cellular metabolic process GO:0031324 382 0.043
dna integrity checkpoint GO:0031570 81 0.042
Yeast
reproductive system development GO:0061458 74 0.042
organic substance catabolic process GO:1901575 308 0.041
cellular macromolecular complex assembly GO:0034622 153 0.041
regulation of meiosis GO:0040020 3 0.041
regulation of cell cycle process GO:0010564 181 0.041
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.040
regulation of cellular protein metabolic process GO:0032268 243 0.039
cell cycle checkpoint GO:0000075 95 0.038
regulation of cell cycle GO:0051726 291 0.037
mrna splicing via spliceosome GO:0000398 73 0.037
regulation of response to external stimulus GO:0032101 115 0.037
reproductive structure development GO:0048608 74 0.036
negative regulation of signaling GO:0023057 219 0.036
regulation of protein metabolic process GO:0051246 256 0.035
regulation of catabolic process GO:0009894 170 0.034
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.034
sex differentiation GO:0007548 81 0.034
larval development GO:0002164 104 0.034
reproductive behavior GO:0019098 122 0.034
regulation of intracellular transport GO:0032386 64 0.033
macromolecular complex assembly GO:0065003 256 0.033
mrna processing GO:0006397 104 0.033
single organism catabolic process GO:0044712 228 0.032
mitotic nuclear division GO:0007067 213 0.032
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.032
phosphorylation GO:0016310 294 0.032
peptidyl lysine modification GO:0018205 57 0.031
body morphogenesis GO:0010171 2 0.030
regulation of phosphate metabolic process GO:0019220 210 0.030
negative regulation of developmental process GO:0051093 201 0.030
neurological system process GO:0050877 358 0.030
regulation of cellular amine metabolic process GO:0033238 3 0.030
response to abiotic stimulus GO:0009628 341 0.029
carbohydrate derivative metabolic process GO:1901135 217 0.029
intracellular signal transduction GO:0035556 300 0.028
negative regulation of cell communication GO:0010648 223 0.028
regulation of cellular amino acid metabolic process GO:0006521 0 0.027
regulation of cellular component biogenesis GO:0044087 201 0.026
organelle fission GO:0048285 340 0.026
macromolecule catabolic process GO:0009057 161 0.026
catabolic process GO:0009056 409 0.026
dna packaging GO:0006323 91 0.026
gonad development GO:0008406 50 0.025
positive regulation of signaling GO:0023056 243 0.025
rna processing GO:0006396 147 0.025
regulation of intracellular protein transport GO:0033157 46 0.025
single organism cellular localization GO:1902580 180 0.024
regulation of apoptotic process GO:0042981 130 0.024
positive regulation of response to stimulus GO:0048584 323 0.024
intracellular protein transport GO:0006886 104 0.024
cellular ketone metabolic process GO:0042180 24 0.024
metaphase anaphase transition of cell cycle GO:0044784 28 0.024
amine metabolic process GO:0009308 12 0.024
negative regulation of cell cycle GO:0045786 116 0.023
positive regulation of programmed cell death GO:0043068 62 0.023
nucleoside phosphate metabolic process GO:0006753 162 0.023
negative regulation of signal transduction GO:0009968 206 0.023
regulation of mapk cascade GO:0043408 92 0.023
heterocycle catabolic process GO:0046700 166 0.023
regulation of intracellular signal transduction GO:1902531 236 0.023
regulation of proteolysis GO:0030162 87 0.022
regulation of protein transport GO:0051223 57 0.022
regulation of phosphorylation GO:0042325 147 0.022
positive regulation of heterochromatin assembly GO:0031453 5 0.021
single organism intracellular transport GO:1902582 207 0.021
regulation of cell proliferation GO:0042127 163 0.021
apoptotic process GO:0006915 159 0.021
positive regulation of signal transduction GO:0009967 223 0.021
forebrain development GO:0030900 2 0.021
multi organism behavior GO:0051705 175 0.021
regulation of mrna splicing via spliceosome GO:0048024 64 0.020
regulation of anatomical structure morphogenesis GO:0022603 242 0.020
positive regulation of peptidase activity GO:0010952 29 0.020
regulation of cell cycle phase transition GO:1901987 130 0.020
endocytosis GO:0006897 310 0.020
dna damage checkpoint GO:0000077 78 0.020
vesicle mediated transport GO:0016192 381 0.020
alternative mrna splicing via spliceosome GO:0000380 60 0.020
positive regulation of cell death GO:0010942 69 0.020
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.019
oxoacid metabolic process GO:0043436 103 0.019
muscle organ development GO:0007517 127 0.019
cellular protein modification process GO:0006464 438 0.019
mitotic dna integrity checkpoint GO:0044774 75 0.019
Yeast
regulation of cellular catabolic process GO:0031329 157 0.018
nucleotide metabolic process GO:0009117 161 0.018
response to oxygen containing compound GO:1901700 200 0.018
programmed cell death GO:0012501 257 0.018
small gtpase mediated signal transduction GO:0007264 88 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.018
locomotory behavior GO:0007626 176 0.018
developmental growth GO:0048589 280 0.018
rna localization GO:0006403 115 0.018
retina development in camera type eye GO:0060041 4 0.018
activation of cysteine type endopeptidase activity GO:0097202 17 0.018
negative regulation of cellular protein metabolic process GO:0032269 85 0.018
mrna metabolic process GO:0016071 124 0.018
positive regulation of phosphorylation GO:0042327 87 0.017
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.017
protein localization GO:0008104 284 0.017
Human
response to organic substance GO:0010033 284 0.017
glycosyl compound catabolic process GO:1901658 112 0.017
nuclear export GO:0051168 24 0.017
negative regulation of organelle organization GO:0010639 56 0.016
regulation of transport GO:0051049 181 0.016
regulation of sister chromatid segregation GO:0033045 28 0.016
regulation of localization GO:0032879 275 0.016
organelle assembly GO:0070925 198 0.016
regulation of multicellular organismal development GO:2000026 414 0.016
cognition GO:0050890 141 0.016
mrna cis splicing via spliceosome GO:0045292 1 0.016
regulation of translation GO:0006417 56 0.016
sensory organ morphogenesis GO:0090596 260 0.016
eye morphogenesis GO:0048592 260 0.016
signal transduction by phosphorylation GO:0023014 107 0.016
cardiovascular system development GO:0072358 82 0.015
regulation of protein localization GO:0032880 76 0.015
camera type eye development GO:0043010 4 0.015
ras protein signal transduction GO:0007265 88 0.015
meiotic dna double strand break formation GO:0042138 1 0.015
regulation of heterochromatin assembly GO:0031445 8 0.015
protein complex assembly GO:0006461 200 0.015
negative regulation of cell differentiation GO:0045596 143 0.015
purine ribonucleotide metabolic process GO:0009150 145 0.015
regulation of cell division GO:0051302 72 0.015
regionalization GO:0003002 416 0.015
purine containing compound metabolic process GO:0072521 155 0.015
negative regulation of protein metabolic process GO:0051248 85 0.015
embryonic hindgut morphogenesis GO:0048619 48 0.014
cellular modified amino acid metabolic process GO:0006575 45 0.014
regulation of mitotic sister chromatid segregation GO:0033047 28 0.014
histone acetylation GO:0016573 38 0.014
cell cell signaling involved in cell fate commitment GO:0045168 210 0.014
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.014
positive regulation of intracellular signal transduction GO:1902533 116 0.014
regulation of dna metabolic process GO:0051052 34 0.014
positive regulation of cellular amine metabolic process GO:0033240 0 0.014
purine nucleoside metabolic process GO:0042278 127 0.014
mitotic dna damage checkpoint GO:0044773 74 0.014
histone modification GO:0016570 106 0.014
negative regulation of biosynthetic process GO:0009890 277 0.014
genitalia development GO:0048806 26 0.014
peptidyl arginine methylation GO:0018216 5 0.014
negative regulation of mitotic cell cycle GO:0045930 109 0.014
establishment of protein localization GO:0045184 163 0.014
negative regulation of cellular component organization GO:0051129 108 0.013
gland development GO:0048732 191 0.013
multicellular organism growth GO:0035264 46 0.013
ribonucleotide metabolic process GO:0009259 145 0.013
protein maturation GO:0051604 71 0.013
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.013
protein alkylation GO:0008213 43 0.013
sulfur compound metabolic process GO:0006790 59 0.013
segmentation GO:0035282 207 0.013
methylation GO:0032259 47 0.013
negative regulation of cell death GO:0060548 81 0.013
phagocytosis GO:0006909 215 0.013
regulation of establishment of protein localization GO:0070201 61 0.013
purine nucleotide catabolic process GO:0006195 109 0.013
positive regulation of intracellular transport GO:0032388 42 0.013
regulation of molecular function GO:0065009 217 0.012
mapk cascade GO:0000165 107 0.012
negative regulation of cell cycle phase transition GO:1901988 103 0.012
carboxylic acid metabolic process GO:0019752 92 0.012
positive regulation of protein metabolic process GO:0051247 128 0.012
regulation of nucleocytoplasmic transport GO:0046822 35 0.012
protein catabolic process GO:0030163 101 0.012
regulation of cell differentiation GO:0045595 302 0.012
cell migration GO:0016477 238 0.012
positive regulation of apoptotic process GO:0043065 47 0.012
cellular macromolecule localization GO:0070727 220 0.012
Human
positive regulation of developmental growth GO:0048639 62 0.012
protein processing GO:0016485 68 0.012
mitotic spindle organization GO:0007052 220 0.012
g2 dna damage checkpoint GO:0031572 69 0.012
mitotic cytokinesis GO:0000281 50 0.012
negative regulation of cellular biosynthetic process GO:0031327 277 0.012
compound eye development GO:0048749 307 0.012
regulation of cytoplasmic transport GO:1903649 47 0.012
macromolecule methylation GO:0043414 45 0.012
histone methylation GO:0016571 40 0.012
atp dependent chromatin remodeling GO:0043044 22 0.011
proteolysis GO:0006508 192 0.011
organic acid metabolic process GO:0006082 103 0.011
rna transport GO:0050658 46 0.011
stem cell division GO:0017145 69 0.011
rna splicing via transesterification reactions GO:0000375 73 0.011
ribose phosphate metabolic process GO:0019693 145 0.011
regulation of mrna metabolic process GO:1903311 72 0.011
regulation of transcription by chromatin organization GO:0034401 3 0.011
organic cyclic compound catabolic process GO:1901361 168 0.011
negative regulation of chromosome organization GO:2001251 19 0.011
response to temperature stimulus GO:0009266 106 0.011
response to other organism GO:0051707 293 0.011
cellular response to organic substance GO:0071310 132 0.011
covalent chromatin modification GO:0016569 106 0.011
regulation of ras protein signal transduction GO:0046578 93 0.011
multicellular organismal reproductive behavior GO:0033057 110 0.011
positive regulation of cellular component organization GO:0051130 156 0.011
cellular amino acid metabolic process GO:0006520 61 0.011
regulation of gene silencing GO:0060968 63 0.010
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.010
positive regulation of phosphate metabolic process GO:0045937 139 0.010
ribonucleotide catabolic process GO:0009261 109 0.010
compound eye photoreceptor cell differentiation GO:0001751 140 0.010
tissue morphogenesis GO:0048729 297 0.010
ribonucleoside triphosphate catabolic process GO:0009203 108 0.010
protein phosphorylation GO:0006468 169 0.010
positive regulation of endopeptidase activity GO:0010950 26 0.010

Bub3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.021
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
organ system cancer DOID:0050686 0 0.013