Drosophila melanogaster

155 known processes

ck (Dmel_CG7595)

crinkled

(Aliases: ck/MyoVIIA,Dm 35B,l(1)35Ca,anon-35Bb,DMyoVIIa,CG7595,l(2)07130,Dro35B,DM7a,ESTS:53D10S,MyoVIIA,53D10S,BG:DS00929.11,stch,D,DmVIIa,br27,myoVIIA,DmVIIA,stc,Mhc35BC,Dmel\CG7595,l(2)br27,l(2)35Ca,D2,l35Ca)

ck biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
actin filament based process GO:0030029 220 0.834
chemotaxis GO:0006935 249 0.619
actin filament organization GO:0007015 126 0.582
imaginal disc derived appendage development GO:0048737 399 0.557
imaginal disc derived wing hair organization GO:0035317 45 0.554
sensory perception of mechanical stimulus GO:0050954 72 0.550
establishment or maintenance of monopolar cell polarity GO:0061339 15 0.550
wing disc morphogenesis GO:0007472 344 0.513
regulation of tube length open tracheal system GO:0035159 24 0.471
cell motility GO:0048870 251 0.428
regulation of multicellular organismal development GO:2000026 414 0.406
negative regulation of response to stimulus GO:0048585 258 0.405
endocytosis GO:0006897 310 0.386
Mouse
cell projection assembly GO:0030031 94 0.383
epithelial cell development GO:0002064 274 0.371
Mouse
vesicle mediated transport GO:0016192 381 0.363
Mouse
regionalization GO:0003002 416 0.357
open tracheal system development GO:0007424 204 0.327
epidermis development GO:0008544 65 0.308
hair cell differentiation GO:0035315 47 0.298
respiratory system development GO:0060541 213 0.274
vesicle organization GO:0016050 44 0.268
Mouse
cell proliferation GO:0008283 299 0.251
heterocycle catabolic process GO:0046700 166 0.248
organic cyclic compound catabolic process GO:1901361 168 0.247
regulation of cell morphogenesis GO:0022604 163 0.230
epithelial cell differentiation GO:0030855 322 0.225
glycosyl compound catabolic process GO:1901658 112 0.212
actin cytoskeleton organization GO:0030036 206 0.196
regulation of anatomical structure size GO:0090066 163 0.195
appendage morphogenesis GO:0035107 397 0.186
multi multicellular organism process GO:0044706 123 0.183
regulation of anatomical structure morphogenesis GO:0022603 242 0.182
appendage development GO:0048736 401 0.181
germline ring canal formation GO:0030725 13 0.177
aromatic compound catabolic process GO:0019439 166 0.168
cellular catabolic process GO:0044248 372 0.165
purine nucleotide catabolic process GO:0006195 109 0.164
protein phosphorylation GO:0006468 169 0.158
multi organism behavior GO:0051705 175 0.158
multicellular organismal reproductive behavior GO:0033057 110 0.153
biological adhesion GO:0022610 138 0.153
nucleotide metabolic process GO:0009117 161 0.149
regulation of molecular function GO:0065009 217 0.145
regulation of cell shape GO:0008360 113 0.143
response to mechanical stimulus GO:0009612 28 0.140
phagocytosis GO:0006909 215 0.139
Mouse
regulation of localization GO:0032879 275 0.134
synapse assembly GO:0007416 143 0.133
epidermal cell differentiation GO:0009913 51 0.130
response to abiotic stimulus GO:0009628 341 0.127
morphogenesis of a polarized epithelium GO:0001738 93 0.122
mating GO:0007618 120 0.122
positive regulation of cellular component organization GO:0051130 156 0.113
ribonucleoside catabolic process GO:0042454 112 0.112
protein modification process GO:0036211 438 0.111
embryonic morphogenesis GO:0048598 206 0.111
Mouse
neurological system process GO:0050877 358 0.111
regulation of cell cycle GO:0051726 291 0.109
regulation of cellular component biogenesis GO:0044087 201 0.106
positive regulation of cellular component biogenesis GO:0044089 80 0.105
axon development GO:0061564 297 0.105
morphogenesis of an epithelium GO:0002009 276 0.105
organophosphate metabolic process GO:0019637 195 0.104
ribonucleoside triphosphate metabolic process GO:0009199 119 0.103
axonogenesis GO:0007409 290 0.103
purine nucleoside metabolic process GO:0042278 127 0.100
cellular nitrogen compound catabolic process GO:0044270 165 0.100
imaginal disc derived appendage morphogenesis GO:0035114 395 0.099
cilium organization GO:0044782 41 0.099
neuron projection guidance GO:0097485 241 0.096
neuron recognition GO:0008038 101 0.096
nucleobase containing compound catabolic process GO:0034655 165 0.095
multi organism reproductive behavior GO:0044705 121 0.094
purine ribonucleoside catabolic process GO:0046130 112 0.093
organelle assembly GO:0070925 198 0.090
Mouse
cell cell signaling involved in cell fate commitment GO:0045168 210 0.089
skin development GO:0043588 65 0.088
central nervous system development GO:0007417 201 0.088
cell recognition GO:0008037 102 0.086
lateral inhibition GO:0046331 206 0.082
initiation of dorsal closure GO:0007392 12 0.078
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.076
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.076
regulation of mrna 3 end processing GO:0031440 7 0.074
response to inorganic substance GO:0010035 44 0.073
cellular component assembly involved in morphogenesis GO:0010927 151 0.073
regulation of peptidase activity GO:0052547 39 0.072
negative regulation of cellular metabolic process GO:0031324 382 0.072
chaeta development GO:0022416 97 0.072
tissue morphogenesis GO:0048729 297 0.070
purine containing compound catabolic process GO:0072523 112 0.069
regulation of gtpase activity GO:0043087 44 0.068
limb development GO:0060173 1 0.068
regulation of cellular component size GO:0032535 98 0.067
taxis GO:0042330 304 0.067
establishment of monopolar cell polarity GO:0061162 15 0.067
organonitrogen compound metabolic process GO:1901564 318 0.067
positive regulation of response to stimulus GO:0048584 323 0.063
imaginal disc derived wing morphogenesis GO:0007476 337 0.063
axon guidance GO:0007411 233 0.063
regulation of apoptotic process GO:0042981 130 0.062
sensory perception of sound GO:0007605 56 0.061
regulation of proteolysis GO:0030162 87 0.060
adult locomotory behavior GO:0008344 76 0.060
establishment of planar polarity GO:0001736 87 0.060
regulation of catalytic activity GO:0050790 185 0.059
localization of cell GO:0051674 257 0.059
photoreceptor cell development GO:0042461 96 0.058
nucleoside triphosphate catabolic process GO:0009143 108 0.057
nucleoside metabolic process GO:0009116 127 0.056
wnt signaling pathway GO:0016055 98 0.056
reproductive behavior GO:0019098 122 0.055
purine ribonucleotide metabolic process GO:0009150 145 0.054
nucleoside phosphate catabolic process GO:1901292 110 0.053
membrane organization GO:0061024 112 0.053
actin cytoskeleton reorganization GO:0031532 22 0.052
positive regulation of gtpase activity GO:0043547 43 0.050
cilium assembly GO:0042384 38 0.050
protein maturation GO:0051604 71 0.049
ribonucleotide catabolic process GO:0009261 109 0.049
cilium morphogenesis GO:0060271 39 0.047
purine ribonucleotide catabolic process GO:0009154 109 0.047
nonmotile primary cilium assembly GO:0035058 8 0.046
actin filament based movement GO:0030048 26 0.045
eye photoreceptor cell development GO:0042462 81 0.043
blastoderm segmentation GO:0007350 159 0.043
establishment of body hair or bristle planar orientation GO:0048104 6 0.042
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.042
phosphorylation GO:0016310 294 0.042
negative regulation of multicellular organismal process GO:0051241 142 0.041
posttranscriptional regulation of gene expression GO:0010608 145 0.041
positive regulation of catalytic activity GO:0043085 118 0.041
cell junction organization GO:0034330 57 0.041
carbohydrate derivative metabolic process GO:1901135 217 0.041
germarium derived egg chamber formation GO:0007293 101 0.040
purine nucleoside triphosphate metabolic process GO:0009144 119 0.040
positive regulation of hydrolase activity GO:0051345 78 0.040
negative regulation of rna metabolic process GO:0051253 251 0.040
gtp catabolic process GO:0006184 72 0.040
eye photoreceptor cell differentiation GO:0001754 145 0.040
establishment of imaginal disc derived wing hair orientation GO:0001737 24 0.040
nucleotide catabolic process GO:0009166 109 0.039
single organism catabolic process GO:0044712 228 0.039
dendrite self avoidance GO:0070593 8 0.039
regulation of phosphorus metabolic process GO:0051174 210 0.039
camera type eye development GO:0043010 4 0.038
cell cell junction organization GO:0045216 55 0.038
segmentation GO:0035282 207 0.038
embryo development ending in birth or egg hatching GO:0009792 152 0.038
nucleoside phosphate metabolic process GO:0006753 162 0.038
negative regulation of signaling GO:0023057 219 0.037
actin filament bundle organization GO:0061572 28 0.037
cell adhesion GO:0007155 136 0.036
regulation of actin filament length GO:0030832 27 0.036
regulation of axonogenesis GO:0050770 32 0.035
ribonucleoside metabolic process GO:0009119 127 0.035
mating behavior GO:0007617 106 0.035
positive regulation of transport GO:0051050 92 0.035
regulation of epithelial cell differentiation GO:0030856 4 0.035
positive regulation of cell motility GO:2000147 3 0.035
proteolysis GO:0006508 192 0.034
glycosyl compound metabolic process GO:1901657 127 0.034
ribonucleotide metabolic process GO:0009259 145 0.033
tube development GO:0035295 244 0.033
mrna metabolic process GO:0016071 124 0.033
post embryonic appendage morphogenesis GO:0035120 385 0.033
non sensory hair organization GO:0035316 47 0.032
purine ribonucleoside metabolic process GO:0046128 127 0.032
actin filament bundle assembly GO:0051017 26 0.032
regulation of embryonic development GO:0045995 68 0.032
male courtship behavior GO:0008049 63 0.032
regulation of protein metabolic process GO:0051246 256 0.032
regulation of cellular protein metabolic process GO:0032268 243 0.031
embryonic development via the syncytial blastoderm GO:0001700 148 0.031
nucleoside triphosphate metabolic process GO:0009141 120 0.031
rho protein signal transduction GO:0007266 14 0.031
ribose phosphate metabolic process GO:0019693 145 0.031
positive regulation of molecular function GO:0044093 136 0.030
heart development GO:0007507 82 0.030
regulation of establishment of planar polarity GO:0090175 22 0.030
neuroblast division GO:0055057 35 0.030
regulation of actin polymerization or depolymerization GO:0008064 27 0.030
cellular macromolecule catabolic process GO:0044265 136 0.030
positive regulation of cell migration GO:0030335 2 0.030
guanosine containing compound catabolic process GO:1901069 74 0.029
regulation of phosphatase activity GO:0010921 3 0.029
sensory perception GO:0007600 196 0.029
cellular response to endogenous stimulus GO:0071495 80 0.029
positive regulation of transferase activity GO:0051347 26 0.029
regulation of hydrolase activity GO:0051336 97 0.029
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.029
male mating behavior GO:0060179 70 0.029
negative regulation of small gtpase mediated signal transduction GO:0051058 13 0.028
ras protein signal transduction GO:0007265 88 0.028
gtp metabolic process GO:0046039 72 0.028
digestive system development GO:0055123 149 0.028
positive regulation of macromolecule metabolic process GO:0010604 405 0.028
regulation of nucleoside metabolic process GO:0009118 50 0.027
cellular protein modification process GO:0006464 438 0.027
nucleobase containing small molecule metabolic process GO:0055086 174 0.027
jnk cascade GO:0007254 50 0.027
regulation of cell cycle process GO:0010564 181 0.027
wound healing GO:0042060 75 0.027
regulation of organelle organization GO:0033043 196 0.027
negative regulation of cell death GO:0060548 81 0.026
body morphogenesis GO:0010171 2 0.026
anterior posterior pattern specification GO:0009952 136 0.026
spermatid development GO:0007286 98 0.026
regulation of cell projection organization GO:0031344 92 0.025
protein complex assembly GO:0006461 200 0.025
enzyme linked receptor protein signaling pathway GO:0007167 179 0.025
positive regulation of signal transduction GO:0009967 223 0.025
notch signaling pathway GO:0007219 120 0.024
head development GO:0060322 135 0.024
sarcomere organization GO:0045214 26 0.024
cuticle pattern formation GO:0035017 27 0.024
negative regulation of phosphatase activity GO:0010923 3 0.024
maintenance of location GO:0051235 73 0.024
digestive tract development GO:0048565 149 0.024
specification of symmetry GO:0009799 13 0.023
syncytium formation GO:0006949 43 0.023
retina development in camera type eye GO:0060041 4 0.023
defense response GO:0006952 300 0.023
purine containing compound metabolic process GO:0072521 155 0.023
compound eye development GO:0048749 307 0.023
photoreceptor cell differentiation GO:0046530 170 0.022
regulation of cell proliferation GO:0042127 163 0.022
organic substance catabolic process GO:1901575 308 0.022
synapse organization GO:0050808 196 0.022
regulation of protein modification process GO:0031399 112 0.022
regulation of nucleotide catabolic process GO:0030811 48 0.021
organophosphate catabolic process GO:0046434 112 0.021
single organism biosynthetic process GO:0044711 206 0.021
purine nucleoside triphosphate catabolic process GO:0009146 108 0.021
regulation of synapse organization GO:0050807 110 0.020
response to radiation GO:0009314 155 0.020
carbohydrate derivative catabolic process GO:1901136 118 0.020
purine nucleotide metabolic process GO:0006163 146 0.020
cell maturation GO:0048469 144 0.020
positive regulation of protein serine threonine kinase activity GO:0071902 15 0.020
purine nucleoside catabolic process GO:0006152 112 0.020
maintenance of protein location GO:0045185 28 0.019
eye development GO:0001654 323 0.019
death GO:0016265 284 0.019
negative regulation of programmed cell death GO:0043069 72 0.019
positive regulation of gtp catabolic process GO:0033126 43 0.019
ribonucleoside triphosphate catabolic process GO:0009203 108 0.019
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.019
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 1 0.019
intracellular signal transduction GO:0035556 300 0.019
positive regulation of ras gtpase activity GO:0032320 36 0.018
organelle fusion GO:0048284 46 0.018
muscle attachment GO:0016203 36 0.018
regulation of protein complex assembly GO:0043254 42 0.018
regulation of tube size GO:0035150 46 0.018
actin filament polymerization GO:0030041 27 0.018
left right pattern formation GO:0060972 1 0.018
regulation of mitotic cell cycle GO:0007346 190 0.018
regulation of phosphate metabolic process GO:0019220 210 0.018
regulation of vesicle mediated transport GO:0060627 59 0.017
regulation of jnk cascade GO:0046328 40 0.017
regulation of wnt signaling pathway GO:0030111 68 0.017
negative regulation of gene expression GO:0010629 387 0.017
adherens junction organization GO:0034332 27 0.017
negative regulation of signal transduction GO:0009968 206 0.017
regulation of cell development GO:0060284 215 0.016
male gamete generation GO:0048232 201 0.016
immune system process GO:0002376 347 0.016
gonad development GO:0008406 50 0.016
positive regulation of viral process GO:0048524 2 0.016
macromolecule catabolic process GO:0009057 161 0.016
protein processing GO:0016485 68 0.016
reproductive system development GO:0061458 74 0.016
hindbrain development GO:0030902 2 0.016
nucleoside catabolic process GO:0009164 112 0.015
regulation of necrotic cell death GO:0010939 1 0.015
cell migration GO:0016477 238 0.015
cardiovascular system development GO:0072358 82 0.015
spinal cord development GO:0021510 1 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.014
response to organophosphorus GO:0046683 2 0.014
positive regulation of chromatin modification GO:1903310 17 0.014
small molecule metabolic process GO:0044281 305 0.014
dorsal ventral pattern formation GO:0009953 133 0.014
regulation of organ morphogenesis GO:2000027 78 0.014
maintenance of protein location in cell GO:0032507 26 0.014
macromolecular complex assembly GO:0065003 256 0.014
regulation of tube size open tracheal system GO:0035151 43 0.014
organonitrogen compound catabolic process GO:1901565 128 0.014
spermatogenesis GO:0007283 200 0.014
positive regulation of cell cycle g2 m phase transition GO:1902751 2 0.014
cytoskeleton dependent cytokinesis GO:0061640 81 0.014
single organism cell adhesion GO:0098602 47 0.014
positive regulation of cellular protein metabolic process GO:0032270 118 0.014
metal ion homeostasis GO:0055065 44 0.014
positive regulation of kinase activity GO:0033674 25 0.013
regulation of cell projection assembly GO:0060491 30 0.013
substrate dependent cell migration GO:0006929 3 0.013
single organism behavior GO:0044708 391 0.013
developmental maturation GO:0021700 172 0.013
determination of bilateral symmetry GO:0009855 13 0.013
embryonic pattern specification GO:0009880 174 0.013
lysosome localization GO:0032418 1 0.013
negative regulation of biosynthetic process GO:0009890 277 0.013
ovarian follicle cell migration GO:0007297 121 0.013
regulation of purine nucleotide catabolic process GO:0033121 48 0.013
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.013
cytokinesis GO:0000910 90 0.013
regulation of embryonic cell shape GO:0016476 30 0.013
gastrulation with mouth forming first GO:0001703 36 0.012
immune response activating signal transduction GO:0002757 2 0.012
cytokinetic cell separation GO:0000920 1 0.012
syncytium formation by plasma membrane fusion GO:0000768 43 0.012
regulation of ras gtpase activity GO:0032318 38 0.012
protein polymerization GO:0051258 42 0.012
negative regulation of cell communication GO:0010648 223 0.012
regulation of transport GO:0051049 181 0.012
positive regulation of phosphate metabolic process GO:0045937 139 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.012
regulation of purine nucleotide metabolic process GO:1900542 62 0.012
proteasomal protein catabolic process GO:0010498 59 0.012
imaginal disc derived female genitalia development GO:0007486 6 0.012
small gtpase mediated signal transduction GO:0007264 88 0.012
humoral immune response GO:0006959 117 0.011
rna 3 end processing GO:0031123 45 0.011
positive regulation of nucleotide metabolic process GO:0045981 55 0.011
regulation of hemocyte proliferation GO:0035206 37 0.011
determination of left right symmetry GO:0007368 9 0.011
rhabdomere development GO:0042052 38 0.011
stress activated mapk cascade GO:0051403 52 0.011
regulation of cytoskeleton organization GO:0051493 89 0.011
regulation of protein localization GO:0032880 76 0.011
catabolic process GO:0009056 409 0.011
oocyte development GO:0048599 124 0.011
reproductive structure development GO:0048608 74 0.011
modification dependent macromolecule catabolic process GO:0043632 79 0.011
golgi vesicle transport GO:0048193 27 0.011
regulation of actin filament polymerization GO:0030833 25 0.011
cell death GO:0008219 279 0.011
oocyte anterior posterior axis specification GO:0007314 72 0.011
ovarian nurse cell to oocyte transport GO:0007300 27 0.011
positive regulation of catabolic process GO:0009896 105 0.010
dorsal closure GO:0007391 79 0.010
regulation of synapse assembly GO:0051963 94 0.010
larval development GO:0002164 104 0.010
actin polymerization or depolymerization GO:0008154 31 0.010
sensory organ morphogenesis GO:0090596 260 0.010
Mouse
imaginal disc derived wing hair site selection GO:0035320 4 0.010
positive regulation of apoptotic cell clearance GO:2000427 2 0.010
regulation of stress activated mapk cascade GO:0032872 41 0.010
meiotic cell cycle process GO:1903046 132 0.010
kidney development GO:0001822 3 0.010
regulation of programmed cell death GO:0043067 152 0.010

ck disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014