Drosophila melanogaster

132 known processes

Spt5 (Dmel_CG7626)

CG7626 gene product from transcript CG7626-RA

(Aliases: spt5,CG7626,Dspt5,dSpt5,Dmel\CG7626,dDSIF,SPT5,DSIF)

Spt5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of gene expression GO:0010629 387 0.954
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.941
negative regulation of transcription dna templated GO:0045892 237 0.927
embryo development ending in birth or egg hatching GO:0009792 152 0.696
peptidyl lysine acetylation GO:0018394 39 0.599
negative regulation of rna metabolic process GO:0051253 251 0.525
gene silencing GO:0016458 138 0.503
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.503
peptidyl lysine modification GO:0018205 57 0.466
transcription from rna polymerase ii promoter GO:0006366 368 0.451
negative regulation of cellular metabolic process GO:0031324 382 0.418
endocytosis GO:0006897 310 0.416
protein dna complex subunit organization GO:0071824 86 0.411
peptidyl amino acid modification GO:0018193 105 0.392
negative regulation of nucleic acid templated transcription GO:1903507 240 0.350
oocyte differentiation GO:0009994 145 0.339
macromolecular complex assembly GO:0065003 256 0.317
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.316
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.310
protein modification process GO:0036211 438 0.308
positive regulation of macromolecule metabolic process GO:0010604 405 0.293
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.291
cellular protein modification process GO:0006464 438 0.246
negative regulation of biosynthetic process GO:0009890 277 0.244
cell migration GO:0016477 238 0.235
protein acylation GO:0043543 42 0.230
regulation of cellular ketone metabolic process GO:0010565 3 0.218
positive regulation of rna biosynthetic process GO:1902680 266 0.203
regulation of gene expression epigenetic GO:0040029 128 0.194
internal protein amino acid acetylation GO:0006475 38 0.192
regulation of organelle organization GO:0033043 196 0.187
mitotic cell cycle checkpoint GO:0007093 88 0.182
positive regulation of cellular component organization GO:0051130 156 0.181
regulation of cell differentiation GO:0045595 302 0.181
protein localization GO:0008104 284 0.178
response to oxidative stress GO:0006979 86 0.174
negative regulation of cell cycle GO:0045786 116 0.172
regulation of transport GO:0051049 181 0.171
intracellular signal transduction GO:0035556 300 0.170
cellular macromolecular complex assembly GO:0034622 153 0.169
defense response to other organism GO:0098542 225 0.160
positive regulation of rna metabolic process GO:0051254 271 0.156
cell division GO:0051301 248 0.143
cell proliferation GO:0008283 299 0.139
gene silencing by rna GO:0031047 57 0.139
cellular response to chemical stimulus GO:0070887 199 0.136
negative regulation of cell communication GO:0010648 223 0.135
enzyme linked receptor protein signaling pathway GO:0007167 179 0.132
negative regulation of cellular biosynthetic process GO:0031327 277 0.130
negative regulation of cell proliferation GO:0008285 69 0.123
histone modification GO:0016570 106 0.122
positive regulation of signaling GO:0023056 243 0.121
regulation of cellular component biogenesis GO:0044087 201 0.118
eye development GO:0001654 323 0.114
negative regulation of rna biosynthetic process GO:1902679 240 0.112
cellular macromolecule localization GO:0070727 220 0.112
chromatin organization GO:0006325 207 0.110
body morphogenesis GO:0010171 2 0.106
chromatin modification GO:0016568 147 0.106
carboxylic acid metabolic process GO:0019752 92 0.101
positive regulation of gene expression GO:0010628 290 0.097
protein acetylation GO:0006473 39 0.095
positive regulation of developmental process GO:0051094 143 0.091
negative regulation of mitotic cell cycle GO:0045930 109 0.088
protein complex assembly GO:0006461 200 0.088
protein dna complex assembly GO:0065004 63 0.084
peptidyl lysine methylation GO:0018022 16 0.083
regulation of chromatin organization GO:1902275 32 0.079
regulation of chromosome organization GO:0033044 64 0.079
regulation of cellular amino acid metabolic process GO:0006521 0 0.078
regulation of multicellular organismal development GO:2000026 414 0.075
response to bacterium GO:0009617 198 0.070
growth GO:0040007 359 0.070
rna interference GO:0016246 27 0.069
positive regulation of cell communication GO:0010647 250 0.068
meiotic cell cycle GO:0051321 171 0.068
response to oxygen containing compound GO:1901700 200 0.067
positive regulation of signal transduction GO:0009967 223 0.067
cell adhesion GO:0007155 136 0.067
peptidyl lysine trimethylation GO:0018023 6 0.066
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.064
regulation of growth GO:0040008 233 0.063
germarium derived egg chamber formation GO:0007293 101 0.062
negative regulation of signal transduction GO:0009968 206 0.062
chromatin silencing GO:0006342 76 0.061
positive regulation of transcription dna templated GO:0045893 266 0.061
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.060
protein import GO:0017038 55 0.060
regulation of meiosis GO:0040020 3 0.060
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.059
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.058
response to organic substance GO:0010033 284 0.058
nucleosome organization GO:0034728 59 0.058
receptor mediated endocytosis GO:0006898 21 0.058
regulation of programmed cell death GO:0043067 152 0.057
establishment or maintenance of cell polarity GO:0007163 167 0.057
regulation of chromatin modification GO:1903308 28 0.057
negative regulation of cell cycle phase transition GO:1901988 103 0.056
response to external biotic stimulus GO:0043207 293 0.056
cell cycle checkpoint GO:0000075 95 0.056
covalent chromatin modification GO:0016569 106 0.055
immune system process GO:0002376 347 0.053
dorsal ventral pattern formation GO:0009953 133 0.052
negative regulation of signaling GO:0023057 219 0.051
localization of cell GO:0051674 257 0.051
regulation of cell cycle phase transition GO:1901987 130 0.051
regulation of cell proliferation GO:0042127 163 0.050
regulation of chromatin assembly GO:0010847 9 0.050
regulation of protein metabolic process GO:0051246 256 0.049
defense response to bacterium GO:0042742 178 0.049
histone acetylation GO:0016573 38 0.048
regulation of mrna metabolic process GO:1903311 72 0.047
positive regulation of cellular biosynthetic process GO:0031328 316 0.047
endodermal cell differentiation GO:0035987 3 0.046
regulation of cell death GO:0010941 173 0.046
regulation of localization GO:0032879 275 0.046
cell death GO:0008219 279 0.045
single organism cellular localization GO:1902580 180 0.044
reproductive behavior GO:0019098 122 0.043
nuclear division GO:0000280 332 0.043
oocyte axis specification GO:0007309 108 0.042
regulation of multi organism process GO:0043900 131 0.042
death GO:0016265 284 0.042
cellular ketone metabolic process GO:0042180 24 0.042
atp dependent chromatin remodeling GO:0043044 22 0.042
regulation of cell cycle GO:0051726 291 0.041
regulation of mitotic cell cycle GO:0007346 190 0.041
regulation of apoptotic process GO:0042981 130 0.041
positive regulation of cellular amine metabolic process GO:0033240 0 0.041
signal transduction by phosphorylation GO:0023014 107 0.040
embryonic development via the syncytial blastoderm GO:0001700 148 0.040
intracellular protein transport GO:0006886 104 0.040
response to endogenous stimulus GO:0009719 119 0.039
protein transport GO:0015031 155 0.039
regulation of cell cycle process GO:0010564 181 0.038
organic acid metabolic process GO:0006082 103 0.038
organic substance transport GO:0071702 257 0.038
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.038
axis specification GO:0009798 167 0.037
defense response to gram negative bacterium GO:0050829 94 0.037
regulation of cellular localization GO:0060341 136 0.037
regulation of rna splicing GO:0043484 69 0.037
multicellular organismal reproductive behavior GO:0033057 110 0.037
reproductive structure development GO:0048608 74 0.036
internal peptidyl lysine acetylation GO:0018393 38 0.036
regulation of nuclear division GO:0051783 58 0.035
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.034
positive regulation of response to stimulus GO:0048584 323 0.034
regulation of cell development GO:0060284 215 0.033
development of primary sexual characteristics GO:0045137 50 0.033
regulation of cellular protein metabolic process GO:0032268 243 0.033
eye morphogenesis GO:0048592 260 0.033
digestive system development GO:0055123 149 0.032
chromosome organization GO:0051276 360 0.032
protein complex biogenesis GO:0070271 201 0.031
organelle fission GO:0048285 340 0.031
gonad development GO:0008406 50 0.031
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.030
cellular response to endogenous stimulus GO:0071495 80 0.030
sperm chromatin decondensation GO:0035041 5 0.030
response to abiotic stimulus GO:0009628 341 0.030
rna splicing via transesterification reactions GO:0000375 73 0.030
multi multicellular organism process GO:0044706 123 0.029
nuclear transport GO:0051169 72 0.029
establishment of localization in cell GO:0051649 402 0.029
transcription elongation from rna polymerase ii promoter GO:0006368 18 0.029
regulation of phosphorylation GO:0042325 147 0.029
imaginal disc derived leg morphogenesis GO:0007480 80 0.029
negative regulation of response to stimulus GO:0048585 258 0.028
stem cell development GO:0048864 79 0.028
compound eye morphogenesis GO:0001745 249 0.028
male pronucleus assembly GO:0035039 6 0.027
dna methylation or demethylation GO:0044728 4 0.027
regulation of response to stress GO:0080134 200 0.027
camera type eye development GO:0043010 4 0.026
regulation of mrna processing GO:0050684 71 0.026
regulation of intracellular signal transduction GO:1902531 236 0.026
wnt signaling pathway GO:0016055 98 0.026
larval development GO:0002164 104 0.026
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.025
stem cell differentiation GO:0048863 117 0.025
amine metabolic process GO:0009308 12 0.025
posttranscriptional gene silencing by rna GO:0035194 45 0.025
regulation of neuron projection development GO:0010975 69 0.025
cellular response to organic substance GO:0071310 132 0.025
dendrite morphogenesis GO:0048813 199 0.025
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.025
apoptotic process GO:0006915 159 0.024
digestive tract morphogenesis GO:0048546 127 0.024
positive regulation of ras protein signal transduction GO:0046579 43 0.024
rna processing GO:0006396 147 0.024
regulation of small gtpase mediated signal transduction GO:0051056 93 0.024
rna splicing GO:0008380 83 0.024
protein localization to organelle GO:0033365 82 0.024
segmentation GO:0035282 207 0.024
positive regulation of organelle organization GO:0010638 65 0.023
mrna metabolic process GO:0016071 124 0.023
homeostatic process GO:0042592 199 0.023
anatomical structure homeostasis GO:0060249 97 0.023
positive regulation of transport GO:0051050 92 0.022
negative regulation of apoptotic process GO:0043066 63 0.022
neural precursor cell proliferation GO:0061351 75 0.022
regulation of phosphate metabolic process GO:0019220 210 0.022
insulin receptor signaling pathway GO:0008286 25 0.022
developmental growth GO:0048589 280 0.022
axon guidance GO:0007411 233 0.021
head development GO:0060322 135 0.021
cellular protein localization GO:0034613 160 0.021
cell motility GO:0048870 251 0.021
regulation of meiotic cell cycle GO:0051445 9 0.021
regulation of cellular amine metabolic process GO:0033238 3 0.021
cell cycle phase transition GO:0044770 140 0.021
maintenance of protein location in cell GO:0032507 26 0.021
regulation of mapk cascade GO:0043408 92 0.021
compound eye development GO:0048749 307 0.021
positive regulation of intracellular signal transduction GO:1902533 116 0.021
regulation of mitotic cell cycle phase transition GO:1901990 130 0.020
intracellular transport GO:0046907 228 0.020
fertilization GO:0009566 26 0.020
protein targeting GO:0006605 64 0.020
erk1 and erk2 cascade GO:0070371 39 0.020
peptidyl threonine phosphorylation GO:0018107 2 0.020
positive regulation of protein import into nucleus GO:0042307 21 0.020
response to nitrogen compound GO:1901698 90 0.019
sex differentiation GO:0007548 81 0.019
histone exchange GO:0043486 21 0.019
rna localization GO:0006403 115 0.019
regulation of cell division GO:0051302 72 0.019
embryonic morphogenesis GO:0048598 206 0.019
positive regulation of cellular component biogenesis GO:0044089 80 0.019
vesicle mediated transport GO:0016192 381 0.019
mitotic nuclear division GO:0007067 213 0.019
programmed cell death GO:0012501 257 0.018
leg disc morphogenesis GO:0007478 80 0.018
response to other organism GO:0051707 293 0.017
organonitrogen compound metabolic process GO:1901564 318 0.017
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 20 0.017
negative regulation of cell cycle process GO:0010948 109 0.017
retina development in camera type eye GO:0060041 4 0.017
regulation of protein transport GO:0051223 57 0.017
positive regulation of mapk cascade GO:0043410 63 0.017
posttranscriptional regulation of gene expression GO:0010608 145 0.016
dna repair GO:0006281 54 0.016
signal transduction in response to dna damage GO:0042770 3 0.016
dna templated transcription elongation GO:0006354 18 0.016
positive regulation of erk1 and erk2 cascade GO:0070374 36 0.016
establishment of protein localization GO:0045184 163 0.016
anterior posterior pattern specification GO:0009952 136 0.016
regionalization GO:0003002 416 0.015
neuron projection guidance GO:0097485 241 0.015
cellular protein catabolic process GO:0044257 83 0.015
regulation of intracellular transport GO:0032386 64 0.015
regulation of immune system process GO:0002682 176 0.015
protein modification by small protein conjugation or removal GO:0070647 106 0.015
chromatin remodeling GO:0006338 72 0.014
protein targeting to nucleus GO:0044744 51 0.014
appendage morphogenesis GO:0035107 397 0.014
methylation GO:0032259 47 0.014
regulation of heterochromatin assembly GO:0031445 8 0.014
reproductive system development GO:0061458 74 0.014
protein modification by small protein conjugation GO:0032446 79 0.014
regulation of developmental growth GO:0048638 174 0.014
immune system development GO:0002520 57 0.014
transcription initiation from rna polymerase ii promoter GO:0006367 25 0.014
cytoplasmic transport GO:0016482 130 0.014
tissue morphogenesis GO:0048729 297 0.014
dna damage checkpoint GO:0000077 78 0.014
cellular response to peptide hormone stimulus GO:0071375 28 0.013
multicellular organism growth GO:0035264 46 0.013
organelle assembly GO:0070925 198 0.013
kidney epithelium development GO:0072073 3 0.013
axon development GO:0061564 297 0.013
stem cell maintenance GO:0019827 67 0.013
cellular amine metabolic process GO:0044106 12 0.013
regulation of nervous system development GO:0051960 248 0.013
regulation of protein complex assembly GO:0043254 42 0.013
protein localization to nucleus GO:0034504 55 0.013
positive regulation of stem cell differentiation GO:2000738 3 0.013
protein import into nucleus GO:0006606 51 0.013
regulation of cellular catabolic process GO:0031329 157 0.013
regulation of peptidyl lysine acetylation GO:2000756 7 0.013
regulation of production of molecular mediator of immune response GO:0002700 44 0.013
spinal cord development GO:0021510 1 0.013
posttranscriptional gene silencing GO:0016441 46 0.013
regulation of protein modification process GO:0031399 112 0.013
histone h4 k20 methylation GO:0034770 4 0.012
oxoacid metabolic process GO:0043436 103 0.012
response to heat GO:0009408 63 0.012
nucleocytoplasmic transport GO:0006913 72 0.012
cellular amino acid metabolic process GO:0006520 61 0.012
response to biotic stimulus GO:0009607 294 0.012
actin cytoskeleton organization GO:0030036 206 0.012
positive regulation of cell proliferation GO:0008284 47 0.012
negative regulation of cellular component organization GO:0051129 108 0.012
germarium derived oocyte differentiation GO:0030706 29 0.012
regulation of neuron differentiation GO:0045664 103 0.012
response to hormone GO:0009725 45 0.012
cellular response to oxygen containing compound GO:1901701 79 0.012
molting cycle GO:0042303 56 0.012
negative regulation of cell differentiation GO:0045596 143 0.012
sensory organ morphogenesis GO:0090596 260 0.012
positive regulation of nucleocytoplasmic transport GO:0046824 24 0.012
nucleosome positioning GO:0016584 3 0.011
phagocytosis GO:0006909 215 0.011
pigment cell differentiation GO:0050931 3 0.011
cellular response to nutrient GO:0031670 1 0.011
digestive tract development GO:0048565 149 0.011
regulation of erk1 and erk2 cascade GO:0070372 39 0.011
positive regulation of phosphorylation GO:0042327 87 0.011
regulation of histone modification GO:0031056 20 0.011
actin filament based process GO:0030029 220 0.011
chromatin assembly or disassembly GO:0006333 52 0.011
dna templated transcriptional preinitiation complex assembly GO:0070897 20 0.011
response to organic cyclic compound GO:0014070 89 0.011
mesenchymal cell differentiation GO:0048762 1 0.011
regulation of nucleocytoplasmic transport GO:0046822 35 0.010
regulation of cell morphogenesis GO:0022604 163 0.010
chemotaxis GO:0006935 249 0.010
response to insulin GO:0032868 29 0.010
ras protein signal transduction GO:0007265 88 0.010
regulation of phosphorus metabolic process GO:0051174 210 0.010
mrna splicing via spliceosome GO:0000398 73 0.010
positive regulation of small gtpase mediated signal transduction GO:0051057 43 0.010
mapk cascade GO:0000165 107 0.010

Spt5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.030
nervous system disease DOID:863 0 0.013