Drosophila melanogaster

55 known processes

Appl (Dmel_CG7727)

beta amyloid protein precursor-like

(Aliases: CG7727,EG:65F1.5,APP,APP-like,Dmel\CG7727,APPL,Abeta,appl,BcDNA:GH04413)

Appl biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of multicellular organismal development GO:2000026 414 0.968
Mouse
regulation of nervous system development GO:0051960 248 0.960
Mouse
single organism behavior GO:0044708 391 0.951
learning GO:0007612 75 0.941
Mouse
sensory perception of sound GO:0007605 56 0.923
regulation of anatomical structure morphogenesis GO:0022603 242 0.907
morphogenesis of an epithelium GO:0002009 276 0.879
Zebrafish
learning or memory GO:0007611 141 0.857
cognition GO:0050890 141 0.840
adult behavior GO:0030534 137 0.671
Mouse
regulation of neurogenesis GO:0050767 158 0.646
Mouse
regulation of cell morphogenesis GO:0022604 163 0.635
regulation of cell development GO:0060284 215 0.635
Mouse
regulation of synapse organization GO:0050807 110 0.577
homeostatic process GO:0042592 199 0.548
Mouse
regulation of synapse structure and activity GO:0050803 128 0.546
Mouse
brain development GO:0007420 120 0.523
Mouse
developmental growth GO:0048589 280 0.506
Mouse Worm
regulation of cell differentiation GO:0045595 302 0.498
Mouse
regulation of response to external stimulus GO:0032101 115 0.498
response to abiotic stimulus GO:0009628 341 0.461
Mouse
memory GO:0007613 94 0.440
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.429
Mouse
synapse assembly GO:0007416 143 0.423
Mouse
deactivation of rhodopsin mediated signaling GO:0016059 17 0.421
adult locomotory behavior GO:0008344 76 0.408
Mouse
locomotory behavior GO:0007626 176 0.406
Mouse
negative regulation of developmental process GO:0051093 201 0.401
Mouse
chemosensory behavior GO:0007635 106 0.393
biological adhesion GO:0022610 138 0.392
cellular protein modification process GO:0006464 438 0.388
Mouse
negative regulation of cellular metabolic process GO:0031324 382 0.386
Human
tissue morphogenesis GO:0048729 297 0.383
Zebrafish
cell cell signaling involved in cell fate commitment GO:0045168 210 0.377
regulation of cellular component biogenesis GO:0044087 201 0.354
reproductive behavior GO:0019098 122 0.353
Mouse
multi organism behavior GO:0051705 175 0.334
Mouse
positive regulation of developmental process GO:0051094 143 0.322
Worm
neurological system process GO:0050877 358 0.313
associative learning GO:0008306 65 0.308
Mouse
regulation of neuron projection development GO:0010975 69 0.296
programmed cell death GO:0012501 257 0.282
Human Mouse
eye morphogenesis GO:0048592 260 0.277
eye development GO:0001654 323 0.263
positive regulation of macromolecule metabolic process GO:0010604 405 0.262
Mouse
regulation of cell cycle GO:0051726 291 0.256
Mouse
chorion containing eggshell formation GO:0007304 105 0.255
cell death GO:0008219 279 0.249
dendrite development GO:0016358 204 0.249
Mouse
positive regulation of cellular component organization GO:0051130 156 0.242
appendage development GO:0048736 401 0.239
detection of light stimulus GO:0009583 58 0.231
regulation of localization GO:0032879 275 0.223
multi multicellular organism process GO:0044706 123 0.222
compound eye development GO:0048749 307 0.219
cell migration GO:0016477 238 0.214
cell growth GO:0016049 108 0.212
Mouse
actin cytoskeleton organization GO:0030036 206 0.211
digestive tract development GO:0048565 149 0.210
synapse organization GO:0050808 196 0.209
sensory perception of mechanical stimulus GO:0050954 72 0.208
regulation of protein modification process GO:0031399 112 0.202
Mouse
positive regulation of response to stimulus GO:0048584 323 0.199
epithelial cell differentiation GO:0030855 322 0.195
compound eye morphogenesis GO:0001745 249 0.194
cell adhesion GO:0007155 136 0.193
dendrite morphogenesis GO:0048813 199 0.192
regulation of programmed cell death GO:0043067 152 0.189
olfactory learning GO:0008355 56 0.187
developmental maturation GO:0021700 172 0.186
Mouse
response to bacterium GO:0009617 198 0.179
regulation of cell death GO:0010941 173 0.174
sensory organ morphogenesis GO:0090596 260 0.170
establishment of organelle localization GO:0051656 122 0.168
lateral inhibition GO:0046331 206 0.166
regulation of organ morphogenesis GO:2000027 78 0.164
protein localization GO:0008104 284 0.162
cell proliferation GO:0008283 299 0.161
localization of cell GO:0051674 257 0.155
renal tubule morphogenesis GO:0061333 44 0.155
neural precursor cell proliferation GO:0061351 75 0.154
response to other organism GO:0051707 293 0.145
death GO:0016265 284 0.145
tube morphogenesis GO:0035239 191 0.144
regulation of cellular amine metabolic process GO:0033238 3 0.143
regulation of neural precursor cell proliferation GO:2000177 35 0.142
morphogenesis of a polarized epithelium GO:0001738 93 0.139
photoreceptor cell differentiation GO:0046530 170 0.137
phototransduction GO:0007602 52 0.136
intracellular signal transduction GO:0035556 300 0.134
embryonic morphogenesis GO:0048598 206 0.132
axonogenesis GO:0007409 290 0.132
Zebrafish Mouse
response to external biotic stimulus GO:0043207 293 0.130
regulation of neuron differentiation GO:0045664 103 0.127
Mouse
terminal button organization GO:0072553 19 0.125
protein complex assembly GO:0006461 200 0.125
axon development GO:0061564 297 0.125
Zebrafish Mouse
eggshell formation GO:0030703 105 0.125
head development GO:0060322 135 0.124
Mouse
protein modification process GO:0036211 438 0.123
Mouse
tube development GO:0035295 244 0.123
regulation of cellular amino acid metabolic process GO:0006521 0 0.122
regulation of dendrite development GO:0050773 37 0.121
retina development in camera type eye GO:0060041 4 0.120
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.118
Mouse
wnt signaling pathway GO:0016055 98 0.117
notch signaling pathway GO:0007219 120 0.115
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.113
Mouse
cell division GO:0051301 248 0.112
camera type eye development GO:0043010 4 0.107
small molecule metabolic process GO:0044281 305 0.106
Mouse
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.103
Mouse
ameboidal type cell migration GO:0001667 151 0.102
response to radiation GO:0009314 155 0.100
Mouse
positive regulation of rna biosynthetic process GO:1902680 266 0.100
Mouse
neuromuscular junction development GO:0007528 149 0.099
Mouse
protein modification by small protein conjugation GO:0032446 79 0.099
long term memory GO:0007616 62 0.098
carboxylic acid metabolic process GO:0019752 92 0.096
response to biotic stimulus GO:0009607 294 0.096
regulation of cell projection organization GO:0031344 92 0.096
positive regulation of cellular component biogenesis GO:0044089 80 0.094
positive regulation of gene expression GO:0010628 290 0.093
Mouse
response to ethanol GO:0045471 59 0.093
regulation of cell proliferation GO:0042127 163 0.092
negative regulation of cell death GO:0060548 81 0.090
response to light stimulus GO:0009416 124 0.090
Mouse
branching morphogenesis of an epithelial tube GO:0048754 45 0.090
regulation of protein metabolic process GO:0051246 256 0.089
Human Mouse
negative regulation of rna biosynthetic process GO:1902679 240 0.089
regulation of epithelial cell proliferation GO:0050678 4 0.089
transcription from rna polymerase ii promoter GO:0006366 368 0.088
Mouse
mating behavior GO:0007617 106 0.087
Mouse
regulation of synapse assembly GO:0051963 94 0.087
cellular ketone metabolic process GO:0042180 24 0.087
positive regulation of cell projection organization GO:0031346 29 0.086
protein modification by small protein conjugation or removal GO:0070647 106 0.085
imaginal disc derived appendage development GO:0048737 399 0.085
regionalization GO:0003002 416 0.084
carbohydrate derivative catabolic process GO:1901136 118 0.083
regulation of response to stress GO:0080134 200 0.083
actin filament based process GO:0030029 220 0.082
imaginal disc derived appendage morphogenesis GO:0035114 395 0.081
epithelial cell development GO:0002064 274 0.080
g protein coupled receptor signaling pathway GO:0007186 136 0.078
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.078
eye photoreceptor cell differentiation GO:0001754 145 0.078
sensory perception GO:0007600 196 0.077
negative regulation of cell differentiation GO:0045596 143 0.076
Mouse
circulatory system development GO:0072359 82 0.074
Zebrafish
appendage morphogenesis GO:0035107 397 0.074
epidermis development GO:0008544 65 0.073
ovarian follicle cell development GO:0030707 248 0.073
cellular catabolic process GO:0044248 372 0.072
amine metabolic process GO:0009308 12 0.069
cellular amino acid metabolic process GO:0006520 61 0.069
heart development GO:0007507 82 0.069
regulation of phosphorus metabolic process GO:0051174 210 0.069
Mouse
eye antennal disc development GO:0035214 60 0.068
organ growth GO:0035265 56 0.068
skin development GO:0043588 65 0.067
mating GO:0007618 120 0.067
Mouse
establishment of planar polarity GO:0001736 87 0.067
chromatin modification GO:0016568 147 0.067
regulation of mitotic cell cycle GO:0007346 190 0.066
Mouse
negative regulation of response to stimulus GO:0048585 258 0.066
positive regulation of signal transduction GO:0009967 223 0.065
embryonic organ development GO:0048568 50 0.065
male mating behavior GO:0060179 70 0.063
positive regulation of cell differentiation GO:0045597 64 0.063
epithelial tube morphogenesis GO:0060562 88 0.063
protein complex biogenesis GO:0070271 201 0.062
growth GO:0040007 359 0.062
Mouse Worm
detection of visible light GO:0009584 38 0.061
positive regulation of rna metabolic process GO:0051254 271 0.061
Mouse
histone modification GO:0016570 106 0.061
cell motility GO:0048870 251 0.061
epithelial cell migration GO:0010631 148 0.059
post embryonic appendage morphogenesis GO:0035120 385 0.059
cellular response to abiotic stimulus GO:0071214 58 0.058
central nervous system development GO:0007417 201 0.058
Zebrafish Mouse
multicellular organismal reproductive behavior GO:0033057 110 0.057
negative regulation of biosynthetic process GO:0009890 277 0.055
embryonic development via the syncytial blastoderm GO:0001700 148 0.055
positive regulation of response to external stimulus GO:0032103 44 0.054
establishment of vesicle localization GO:0051650 51 0.053
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.053
Mouse
axon extension GO:0048675 32 0.053
apoptotic process GO:0006915 159 0.053
Human Mouse
imaginal disc derived wing morphogenesis GO:0007476 337 0.053
epithelium migration GO:0090132 148 0.053
peripheral nervous system development GO:0007422 52 0.052
response to nutrient levels GO:0031667 114 0.052
stem cell differentiation GO:0048863 117 0.052
immune response GO:0006955 246 0.052
regulation of stem cell proliferation GO:0072091 40 0.052
regulation of catalytic activity GO:0050790 185 0.051
Human Mouse
defense response GO:0006952 300 0.051
establishment of localization in cell GO:0051649 402 0.051
Mouse
cellular response to lipopolysaccharide GO:0071222 3 0.051
immune system process GO:0002376 347 0.050
nucleobase containing compound catabolic process GO:0034655 165 0.050
behavioral response to ethanol GO:0048149 49 0.049
negative regulation of cellular biosynthetic process GO:0031327 277 0.048
positive regulation of cellular biosynthetic process GO:0031328 316 0.047
Mouse
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.047
regulation of immune system process GO:0002682 176 0.047
leg disc development GO:0035218 92 0.046
negative regulation of programmed cell death GO:0043069 72 0.046
positive regulation of biosynthetic process GO:0009891 316 0.046
Mouse
male courtship behavior GO:0008049 63 0.045
negative regulation of rna metabolic process GO:0051253 251 0.045
multicellular organismal aging GO:0010259 140 0.045
regulation of cellular protein metabolic process GO:0032268 243 0.045
Human Mouse
neuron projection extension GO:1990138 32 0.045
cardiovascular system development GO:0072358 82 0.044
Zebrafish
compound eye retinal cell programmed cell death GO:0046667 23 0.044
peptidyl threonine phosphorylation GO:0018107 2 0.044
sex differentiation GO:0007548 81 0.044
wing disc morphogenesis GO:0007472 344 0.044
response to organic substance GO:0010033 284 0.043
olfactory behavior GO:0042048 97 0.043
stem cell proliferation GO:0072089 88 0.043
positive regulation of cell death GO:0010942 69 0.042
neural retina development GO:0003407 4 0.042
single organism catabolic process GO:0044712 228 0.041
negative regulation of transcription dna templated GO:0045892 237 0.041
filopodium assembly GO:0046847 33 0.041
regulation of rhodopsin mediated signaling pathway GO:0022400 17 0.041
negative regulation of phosphate metabolic process GO:0045936 45 0.041
negative regulation of phosphorylation GO:0042326 35 0.041
regulation of phosphorylation GO:0042325 147 0.040
Mouse
cytokinesis GO:0000910 90 0.040
regulation of phosphate metabolic process GO:0019220 210 0.040
Mouse
cellular amine metabolic process GO:0044106 12 0.040
cellular response to organic substance GO:0071310 132 0.039
aging GO:0007568 143 0.039
open tracheal system development GO:0007424 204 0.038
regulation of cytoskeleton organization GO:0051493 89 0.038
regulation of vesicle mediated transport GO:0060627 59 0.038
cellular response to starvation GO:0009267 61 0.038
mitotic nuclear division GO:0007067 213 0.038
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.037
branching involved in open tracheal system development GO:0060446 45 0.037
positive regulation of nervous system development GO:0051962 69 0.037
nucleus localization GO:0051647 34 0.037
developmental cell growth GO:0048588 52 0.036
Mouse
vesicle mediated transport GO:0016192 381 0.036
Mouse
cell cell junction assembly GO:0007043 38 0.036
imaginal disc derived wing vein specification GO:0007474 48 0.036
cell fate determination GO:0001709 91 0.035
actin filament organization GO:0007015 126 0.035
establishment or maintenance of apical basal cell polarity GO:0035088 34 0.035
positive regulation of cell proliferation GO:0008284 47 0.035
detection of stimulus GO:0051606 156 0.035
cranial nerve development GO:0021545 1 0.034
eggshell chorion assembly GO:0007306 66 0.034
response to alcohol GO:0097305 95 0.034
dorsal ventral pattern formation GO:0009953 133 0.034
regulation of membrane potential GO:0042391 35 0.034
regulation of mitotic cell cycle phase transition GO:1901990 130 0.034
Mouse
regulation of protein modification by small protein conjugation or removal GO:1903320 25 0.033
phosphorylation GO:0016310 294 0.033
Mouse
cellular response to external stimulus GO:0071496 66 0.033
negative regulation of protein modification process GO:0031400 29 0.033
cellular response to nutrient levels GO:0031669 62 0.033
positive regulation of multicellular organismal process GO:0051240 143 0.033
Worm
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.033
purine ribonucleotide metabolic process GO:0009150 145 0.033
positive regulation of apoptotic process GO:0043065 47 0.032
nucleoside phosphate catabolic process GO:1901292 110 0.032
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.032
organic acid metabolic process GO:0006082 103 0.032
peptidyl amino acid modification GO:0018193 105 0.032
Mouse
protein ubiquitination GO:0016567 70 0.032
stem cell maintenance GO:0019827 67 0.031
response to oxygen containing compound GO:1901700 200 0.031
compound eye photoreceptor cell differentiation GO:0001751 140 0.031
positive regulation of catabolic process GO:0009896 105 0.031
positive regulation of synapse assembly GO:0051965 29 0.031
stem cell development GO:0048864 79 0.031
somatic stem cell division GO:0048103 37 0.031
positive regulation of cell communication GO:0010647 250 0.031
renal tubule development GO:0061326 64 0.030
synaptic growth at neuromuscular junction GO:0051124 119 0.030
Mouse
developmental growth involved in morphogenesis GO:0060560 65 0.030
Mouse
negative regulation of cellular protein metabolic process GO:0032269 85 0.029
Human
positive regulation of cell migration GO:0030335 2 0.029
regulation of intracellular signal transduction GO:1902531 236 0.028
rhodopsin mediated signaling pathway GO:0016056 21 0.028
social behavior GO:0035176 4 0.028
regulation of cellular catabolic process GO:0031329 157 0.028
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.028
salivary gland development GO:0007431 162 0.028
dorsal appendage formation GO:0046843 47 0.028
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.028
positive regulation of molecular function GO:0044093 136 0.028
single organism cell adhesion GO:0098602 47 0.028
cytoplasmic transport GO:0016482 130 0.028
chromatin organization GO:0006325 207 0.027
camera type eye photoreceptor cell differentiation GO:0060219 2 0.027
negative regulation of gene expression GO:0010629 387 0.027
Human
phototransduction visible light GO:0007603 27 0.027
anterior posterior pattern specification GO:0009952 136 0.026
regulation of growth GO:0040008 233 0.026
Mouse Worm
catabolic process GO:0009056 409 0.026
forebrain development GO:0030900 2 0.026
Mouse
columnar cuboidal epithelial cell development GO:0002066 249 0.026
chromosome organization GO:0051276 360 0.026
neuroblast proliferation GO:0007405 74 0.026
metarhodopsin inactivation GO:0016060 5 0.026
positive regulation of cell development GO:0010720 61 0.026
inorganic cation transmembrane transport GO:0098662 61 0.026
chaeta development GO:0022416 97 0.025
epidermal cell differentiation GO:0009913 51 0.025
histone deacetylation GO:0016575 9 0.025
positive regulation of nucleic acid templated transcription GO:1903508 266 0.025
Mouse
bmp signaling pathway GO:0030509 27 0.025
cellular cation homeostasis GO:0030003 38 0.025
Mouse
chaeta morphogenesis GO:0008407 42 0.025
reproductive structure development GO:0048608 74 0.024
single organism cellular localization GO:1902580 180 0.024
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.024
chromatin remodeling GO:0006338 72 0.024
taxis GO:0042330 304 0.024
Mouse
regulation of dendrite morphogenesis GO:0048814 28 0.024
intrinsic apoptotic signaling pathway GO:0097193 16 0.024
courtship behavior GO:0007619 68 0.024
regulation of immune response GO:0050776 118 0.024
organophosphate catabolic process GO:0046434 112 0.024
hindbrain development GO:0030902 2 0.024
cellular response to chemical stimulus GO:0070887 199 0.024
regulation of wnt signaling pathway GO:0030111 68 0.024
synaptic transmission GO:0007268 288 0.024
Mouse
conditioned taste aversion GO:0001661 3 0.024
negative regulation of phosphorus metabolic process GO:0010563 45 0.023
cellular nitrogen compound catabolic process GO:0044270 165 0.023
actin filament polymerization GO:0030041 27 0.023
positive regulation of catalytic activity GO:0043085 118 0.023
autophagy GO:0006914 108 0.023
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.023
guanosine containing compound metabolic process GO:1901068 74 0.023
negative regulation of cell development GO:0010721 62 0.023
Mouse
regulation of molecular function GO:0065009 217 0.022
Human Mouse
embryo development ending in birth or egg hatching GO:0009792 152 0.022
regulation of actin filament polymerization GO:0030833 25 0.022
organic cyclic compound catabolic process GO:1901361 168 0.022
membrane depolarization GO:0051899 4 0.022
regulation of cellular localization GO:0060341 136 0.022
detection of abiotic stimulus GO:0009582 66 0.022
regulation of cell cycle process GO:0010564 181 0.022
Mouse
positive regulation of transcription dna templated GO:0045893 266 0.022
Mouse
kidney epithelium development GO:0072073 3 0.022
male courtship behavior veined wing vibration GO:0016545 21 0.022
imaginal disc derived wing hair organization GO:0035317 45 0.022
intracellular protein transport GO:0006886 104 0.021
regulation of terminal button organization GO:2000331 11 0.021
oocyte differentiation GO:0009994 145 0.021
enzyme linked receptor protein signaling pathway GO:0007167 179 0.021
Mouse
gland morphogenesis GO:0022612 145 0.021
regulation of developmental growth GO:0048638 174 0.021
Mouse Worm
nephron epithelium development GO:0072009 3 0.021
purine ribonucleotide catabolic process GO:0009154 109 0.021
negative regulation of homeostatic process GO:0032845 2 0.021
positive regulation of exocytosis GO:0045921 4 0.021
response to extracellular stimulus GO:0009991 116 0.020
gastrulation GO:0007369 70 0.020
neuron projection guidance GO:0097485 241 0.020
Mouse
divalent metal ion transport GO:0070838 26 0.020
positive regulation of signaling GO:0023056 243 0.020
camera type eye morphogenesis GO:0048593 2 0.020
negative regulation of nucleic acid templated transcription GO:1903507 240 0.020
sensory perception of smell GO:0007608 80 0.019
organonitrogen compound catabolic process GO:1901565 128 0.019
regulation of cellular response to growth factor stimulus GO:0090287 13 0.019
skeletal muscle fiber development GO:0048741 3 0.019
regulation of actin filament based process GO:0032970 42 0.019
negative regulation of cellular component organization GO:0051129 108 0.019
cellular response to molecule of bacterial origin GO:0071219 3 0.019
striated muscle cell differentiation GO:0051146 90 0.019
protein phosphorylation GO:0006468 169 0.019
Mouse
cellular protein localization GO:0034613 160 0.019
myotube cell development GO:0014904 3 0.019
covalent chromatin modification GO:0016569 106 0.019
regulation of catabolic process GO:0009894 170 0.019
negative regulation of signaling GO:0023057 219 0.019
peptidyl threonine modification GO:0018210 3 0.019
telencephalon development GO:0021537 2 0.018
cell junction organization GO:0034330 57 0.018
neuron recognition GO:0008038 101 0.018
Mouse
single organism biosynthetic process GO:0044711 206 0.018
retinal cell programmed cell death GO:0046666 25 0.018
neuron neuron synaptic transmission GO:0007270 14 0.018
ribonucleotide catabolic process GO:0009261 109 0.018
regulation of sequestering of calcium ion GO:0051282 3 0.018
cell maturation GO:0048469 144 0.018
Mouse
mapk cascade GO:0000165 107 0.018
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.017
cellular response to radiation GO:0071478 52 0.017
glycosyl compound catabolic process GO:1901658 112 0.017
ovarian follicle cell migration GO:0007297 121 0.017
regulation of compound eye retinal cell programmed cell death GO:0046669 18 0.017
ensheathment of neurons GO:0007272 10 0.017
regulation of apoptotic process GO:0042981 130 0.017
organic substance transport GO:0071702 257 0.017
negative regulation of epithelial cell proliferation GO:0050680 4 0.017
purine ribonucleoside catabolic process GO:0046130 112 0.016
regulation of epithelial cell differentiation GO:0030856 4 0.016
positive regulation of synaptic growth at neuromuscular junction GO:0045887 26 0.016
response to lipopolysaccharide GO:0032496 4 0.016
oxoacid metabolic process GO:0043436 103 0.016
positive regulation of neuron differentiation GO:0045666 26 0.016
retina morphogenesis in camera type eye GO:0060042 2 0.016
rho protein signal transduction GO:0007266 14 0.016
endoderm formation GO:0001706 3 0.016
nucleoside phosphate metabolic process GO:0006753 162 0.016
limb morphogenesis GO:0035108 1 0.016
leg disc morphogenesis GO:0007478 80 0.016
macromolecule deacylation GO:0098732 11 0.016
negative regulation of protein metabolic process GO:0051248 85 0.016
Human
metal ion homeostasis GO:0055065 44 0.016
Mouse
establishment or maintenance of cell polarity GO:0007163 167 0.015
axis specification GO:0009798 167 0.015
embryonic pattern specification GO:0009880 174 0.015
digestive system development GO:0055123 149 0.015
cellular macromolecular complex assembly GO:0034622 153 0.015
germarium derived egg chamber formation GO:0007293 101 0.015
nucleoside metabolic process GO:0009116 127 0.015
chemotaxis GO:0006935 249 0.015
Mouse
response to wounding GO:0009611 94 0.015
positive regulation of programmed cell death GO:0043068 62 0.015
inorganic ion transmembrane transport GO:0098660 73 0.015
cellular macromolecule localization GO:0070727 220 0.015
tripartite regional subdivision GO:0007351 103 0.015
ribonucleotide metabolic process GO:0009259 145 0.014
gland development GO:0048732 191 0.014
regulation of axonogenesis GO:0050770 32 0.014
regulation of cellular ketone metabolic process GO:0010565 3 0.014
mesenchymal cell development GO:0014031 1 0.014
compound eye photoreceptor development GO:0042051 78 0.014
calcium ion transmembrane transport GO:0070588 17 0.014
asymmetric stem cell division GO:0098722 49 0.014
cell projection assembly GO:0030031 94 0.014
regulation of protein localization GO:0032880 76 0.014
ribonucleoside catabolic process GO:0042454 112 0.014
regulation of actin cytoskeleton organization GO:0032956 42 0.014
regulation of transport GO:0051049 181 0.014
negative regulation of nervous system development GO:0051961 92 0.014
Mouse
response to endogenous stimulus GO:0009719 119 0.014
positive regulation of synaptic vesicle endocytosis GO:1900244 4 0.014
positive regulation of protein metabolic process GO:0051247 128 0.014
organic substance catabolic process GO:1901575 308 0.013
cell cell junction organization GO:0045216 55 0.013
cellular response to biotic stimulus GO:0071216 4 0.013
purine nucleoside metabolic process GO:0042278 127 0.013
actin filament based movement GO:0030048 26 0.013
limb development GO:0060173 1 0.013
protein import into nucleus GO:0006606 51 0.013
organophosphate metabolic process GO:0019637 195 0.013
regulation of multicellular organism growth GO:0040014 40 0.013
Mouse Worm
gtp catabolic process GO:0006184 72 0.013
purine nucleotide catabolic process GO:0006195 109 0.013
nuclear transport GO:0051169 72 0.013
anterior posterior axis specification embryo GO:0008595 103 0.013
single organism membrane organization GO:0044802 93 0.013
protein transport GO:0015031 155 0.013
regulation of cellular component movement GO:0051270 42 0.013
regulation of protein polymerization GO:0032271 28 0.013
oocyte development GO:0048599 124 0.013
defense response to other organism GO:0098542 225 0.013
photoreceptor cell development GO:0042461 96 0.012
establishment of tissue polarity GO:0007164 87 0.012
epithelial cell morphogenesis GO:0003382 25 0.012
cellular response to growth factor stimulus GO:0071363 30 0.012
protein targeting GO:0006605 64 0.012
negative regulation of cell proliferation GO:0008285 69 0.012
detection of external stimulus GO:0009581 66 0.012
urogenital system development GO:0001655 72 0.012
ribonucleoside triphosphate metabolic process GO:0009199 119 0.012
morphogenesis of a branching epithelium GO:0061138 45 0.012
specification of symmetry GO:0009799 13 0.012
nerve development GO:0021675 6 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.012
positive regulation of cellular catabolic process GO:0031331 95 0.012
multi organism reproductive behavior GO:0044705 121 0.012
Mouse
regulation of g protein coupled receptor protein signaling pathway GO:0008277 23 0.012
embryonic axis specification GO:0000578 107 0.012
glial cell differentiation GO:0010001 35 0.012
carbohydrate derivative metabolic process GO:1901135 217 0.011
short term memory GO:0007614 19 0.011
immune system development GO:0002520 57 0.011
nuclear migration GO:0007097 20 0.011
protein deacetylation GO:0006476 9 0.011

Appl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.083
Human
disease of cellular proliferation DOID:14566 0 0.014
central nervous system disease DOID:331 0 0.013
Human
nervous system disease DOID:863 0 0.013
Human