Drosophila melanogaster

151 known processes

mrn (Dmel_CG7764)

marionette

(Aliases: l(3)E35,Dmel\CG7764,ms(3)nc16,nc16,Tfb2,CG7764,TFB2,Dmp52,anon-WO0118547.648,154538_at,p52)

mrn biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna metabolic process GO:0006259 227 0.981
chromosome organization GO:0051276 360 0.950
negative regulation of nucleic acid templated transcription GO:1903507 240 0.931
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.910
positive regulation of biosynthetic process GO:0009891 316 0.887
negative regulation of cellular biosynthetic process GO:0031327 277 0.854
regulation of multicellular organism growth GO:0040014 40 0.839
dna conformation change GO:0071103 105 0.822
negative regulation of biosynthetic process GO:0009890 277 0.817
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.807
organelle fission GO:0048285 340 0.753
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.709
negative regulation of rna biosynthetic process GO:1902679 240 0.670
death GO:0016265 284 0.664
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.626
negative regulation of transcription dna templated GO:0045892 237 0.607
regulation of cell death GO:0010941 173 0.603
positive regulation of rna metabolic process GO:0051254 271 0.584
cell death GO:0008219 279 0.581
dna replication GO:0006260 48 0.567
germarium derived egg chamber formation GO:0007293 101 0.534
meiotic cell cycle GO:0051321 171 0.525
negative regulation of rna metabolic process GO:0051253 251 0.492
chromosome segregation GO:0007059 157 0.472
establishment of localization in cell GO:0051649 402 0.445
nuclear division GO:0000280 332 0.422
negative regulation of cellular metabolic process GO:0031324 382 0.419
catabolic process GO:0009056 409 0.387
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.385
apoptotic signaling pathway GO:0097190 27 0.381
carbohydrate derivative metabolic process GO:1901135 217 0.376
response to organic substance GO:0010033 284 0.376
negative regulation of developmental process GO:0051093 201 0.343
synapse organization GO:0050808 196 0.341
programmed cell death GO:0012501 257 0.331
positive regulation of rna biosynthetic process GO:1902680 266 0.330
regulation of programmed cell death GO:0043067 152 0.312
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.305
positive regulation of cellular biosynthetic process GO:0031328 316 0.301
regulation of gene expression epigenetic GO:0040029 128 0.296
response to dsrna GO:0043331 15 0.290
organic substance catabolic process GO:1901575 308 0.280
positive regulation of multicellular organismal process GO:0051240 143 0.263
positive regulation of macromolecule metabolic process GO:0010604 405 0.254
nucleobase containing compound catabolic process GO:0034655 165 0.254
negative regulation of gene expression GO:0010629 387 0.236
regulation of multicellular organismal development GO:2000026 414 0.203
regulation of developmental growth GO:0048638 174 0.198
response to external biotic stimulus GO:0043207 293 0.192
regulation of mitotic cell cycle GO:0007346 190 0.181
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.176
cellular nitrogen compound catabolic process GO:0044270 165 0.175
regulation of dna metabolic process GO:0051052 34 0.173
cellular catabolic process GO:0044248 372 0.171
posttranscriptional gene silencing by rna GO:0035194 45 0.168
regulation of cell cycle process GO:0010564 181 0.162
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.160
regulation of growth GO:0040008 233 0.160
negative regulation of cell differentiation GO:0045596 143 0.158
sister chromatid segregation GO:0000819 92 0.156
cellular protein modification process GO:0006464 438 0.155
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.153
chromatin silencing GO:0006342 76 0.138
cellular macromolecule catabolic process GO:0044265 136 0.136
purine nucleoside triphosphate metabolic process GO:0009144 119 0.136
negative regulation of cell death GO:0060548 81 0.135
nucleobase containing small molecule metabolic process GO:0055086 174 0.132
meiotic chromosome segregation GO:0045132 59 0.126
chromatin modification GO:0016568 147 0.118
homeostatic process GO:0042592 199 0.115
positive regulation of nurse cell apoptotic process GO:0045850 5 0.115
purine ribonucleoside metabolic process GO:0046128 127 0.114
cell proliferation GO:0008283 299 0.113
mitotic nuclear division GO:0007067 213 0.112
macromolecular complex assembly GO:0065003 256 0.111
nucleoside phosphate metabolic process GO:0006753 162 0.108
cellular macromolecular complex assembly GO:0034622 153 0.108
transcription from rna polymerase ii promoter GO:0006366 368 0.108
positive regulation of nucleic acid templated transcription GO:1903508 266 0.107
ribonucleoprotein complex subunit organization GO:0071826 28 0.103
ribonucleoprotein complex assembly GO:0022618 23 0.103
regulation of cellular component biogenesis GO:0044087 201 0.103
organonitrogen compound metabolic process GO:1901564 318 0.099
gene silencing by rna GO:0031047 57 0.099
mitotic sister chromatid segregation GO:0000070 87 0.099
positive regulation of gene expression GO:0010628 290 0.096
germarium derived female germ line cyst formation GO:0030727 42 0.095
positive regulation of programmed cell death GO:0043068 62 0.093
regulation of localization GO:0032879 275 0.086
regulation of cell cycle GO:0051726 291 0.085
meiotic cell cycle process GO:1903046 132 0.084
regulation of organelle organization GO:0033043 196 0.083
posttranscriptional gene silencing GO:0016441 46 0.081
developmental programmed cell death GO:0010623 138 0.079
mitotic chromosome condensation GO:0007076 22 0.077
chromatin organization GO:0006325 207 0.076
ribonucleotide metabolic process GO:0009259 145 0.074
apoptotic process GO:0006915 159 0.074
chromosome condensation GO:0030261 41 0.073
spindle assembly involved in mitosis GO:0090307 50 0.073
regulation of multi organism process GO:0043900 131 0.072
response to abiotic stimulus GO:0009628 341 0.072
positive regulation of developmental growth GO:0048639 62 0.072
small molecule metabolic process GO:0044281 305 0.071
multicellular organism growth GO:0035264 46 0.070
cellular protein complex assembly GO:0043623 71 0.070
chromatin remodeling GO:0006338 72 0.067
regulation of apoptotic process GO:0042981 130 0.067
cytoplasmic transport GO:0016482 130 0.066
regulation of transport GO:0051049 181 0.064
gene silencing GO:0016458 138 0.064
regulation of protein metabolic process GO:0051246 256 0.060
g2 dna damage checkpoint GO:0031572 69 0.059
glycosyl compound metabolic process GO:1901657 127 0.058
columnar cuboidal epithelial cell development GO:0002066 249 0.057
regulation of nervous system development GO:0051960 248 0.056
regulation of cellular localization GO:0060341 136 0.055
nucleotide metabolic process GO:0009117 161 0.054
cellular response to organic substance GO:0071310 132 0.054
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.052
negative regulation of signaling GO:0023057 219 0.052
stem cell differentiation GO:0048863 117 0.050
anatomical structure homeostasis GO:0060249 97 0.050
atp metabolic process GO:0046034 49 0.048
protein modification process GO:0036211 438 0.047
positive regulation of developmental process GO:0051094 143 0.047
dna packaging GO:0006323 91 0.047
peptidyl amino acid modification GO:0018193 105 0.046
growth GO:0040007 359 0.045
positive regulation of transcription dna templated GO:0045893 266 0.045
negative regulation of programmed cell death GO:0043069 72 0.044
epithelial cell differentiation GO:0030855 322 0.044
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.044
karyosome formation GO:0030717 22 0.043
organophosphate metabolic process GO:0019637 195 0.042
organic acid metabolic process GO:0006082 103 0.042
negative regulation of multicellular organismal process GO:0051241 142 0.042
gonad development GO:0008406 50 0.041
positive regulation of transport GO:0051050 92 0.041
developmental growth GO:0048589 280 0.041
defense response GO:0006952 300 0.040
organic substance transport GO:0071702 257 0.040
regulation of cell development GO:0060284 215 0.039
female germ line cyst formation GO:0048135 42 0.039
response to nitrogen compound GO:1901698 90 0.038
mitotic spindle organization GO:0007052 220 0.038
neural precursor cell proliferation GO:0061351 75 0.036
negative regulation of signal transduction GO:0009968 206 0.036
cellular response to abiotic stimulus GO:0071214 58 0.036
positive regulation of multicellular organism growth GO:0040018 21 0.036
cuticle development GO:0042335 86 0.036
regulation of phosphate metabolic process GO:0019220 210 0.035
covalent chromatin modification GO:0016569 106 0.034
regulation of catabolic process GO:0009894 170 0.033
cell migration GO:0016477 238 0.033
dna geometric change GO:0032392 16 0.033
intracellular signal transduction GO:0035556 300 0.033
endocytosis GO:0006897 310 0.032
aging GO:0007568 143 0.032
double strand break repair GO:0006302 26 0.032
epithelial cell development GO:0002064 274 0.032
negative regulation of chromosome segregation GO:0051985 14 0.031
spindle organization GO:0007051 253 0.031
male gamete generation GO:0048232 201 0.031
telomere organization GO:0032200 21 0.031
purine containing compound metabolic process GO:0072521 155 0.031
organic cyclic compound catabolic process GO:1901361 168 0.030
ribonucleoside metabolic process GO:0009119 127 0.030
mitotic cell cycle checkpoint GO:0007093 88 0.030
response to radiation GO:0009314 155 0.030
vesicle mediated transport GO:0016192 381 0.029
response to oxygen containing compound GO:1901700 200 0.029
mitotic cell cycle phase transition GO:0044772 138 0.029
development of primary sexual characteristics GO:0045137 50 0.028
molting cycle GO:0042303 56 0.028
oxoacid metabolic process GO:0043436 103 0.028
sex differentiation GO:0007548 81 0.028
lipid metabolic process GO:0006629 121 0.027
regulation of protein transport GO:0051223 57 0.027
stem cell development GO:0048864 79 0.027
positive regulation of phosphate metabolic process GO:0045937 139 0.026
regulation of golgi to plasma membrane protein transport GO:0042996 6 0.026
negative regulation of apoptotic process GO:0043066 63 0.025
histone modification GO:0016570 106 0.025
cell cycle phase transition GO:0044770 140 0.025
macromolecule catabolic process GO:0009057 161 0.025
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.025
negative regulation of neurotransmitter secretion GO:0046929 2 0.024
mitochondrial fusion GO:0008053 7 0.024
organonitrogen compound biosynthetic process GO:1901566 117 0.024
positive regulation of cell death GO:0010942 69 0.024
instar larval development GO:0002168 55 0.023
single organism intracellular transport GO:1902582 207 0.023
ribonucleoside triphosphate catabolic process GO:0009203 108 0.023
cellular response to dna damage stimulus GO:0006974 223 0.023
positive regulation of intracellular transport GO:0032388 42 0.023
tube development GO:0035295 244 0.023
regulation of intracellular signal transduction GO:1902531 236 0.022
phagocytosis GO:0006909 215 0.022
nitric oxide metabolic process GO:0046209 1 0.022
digestive tract morphogenesis GO:0048546 127 0.022
negative regulation of gene expression epigenetic GO:0045814 77 0.021
regulation of meiosis GO:0040020 3 0.021
morphogenesis of follicular epithelium GO:0016333 36 0.021
mitotic recombination GO:0006312 2 0.021
response to endogenous stimulus GO:0009719 119 0.021
nucleoside monophosphate catabolic process GO:0009125 39 0.021
negative regulation of cell communication GO:0010648 223 0.020
regulation of cytoskeleton organization GO:0051493 89 0.020
molting cycle chitin based cuticle GO:0007591 56 0.020
single organism biosynthetic process GO:0044711 206 0.020
positive regulation of cell communication GO:0010647 250 0.019
regulation of cell division GO:0051302 72 0.019
response to biotic stimulus GO:0009607 294 0.019
organelle assembly GO:0070925 198 0.018
purine nucleoside metabolic process GO:0042278 127 0.018
regulation of calcium ion transmembrane transport GO:1903169 2 0.018
locomotory behavior GO:0007626 176 0.017
carbohydrate derivative catabolic process GO:1901136 118 0.017
negative regulation of neuroblast proliferation GO:0007406 27 0.017
ovarian follicle cell stalk formation GO:0030713 17 0.017
nucleoside metabolic process GO:0009116 127 0.017
regulation of mitotic cell cycle phase transition GO:1901990 130 0.017
negative regulation of organelle organization GO:0010639 56 0.017
intracellular transport GO:0046907 228 0.016
dna integrity checkpoint GO:0031570 81 0.016
tube morphogenesis GO:0035239 191 0.016
regulation of catalytic activity GO:0050790 185 0.016
nitrogen compound transport GO:0071705 85 0.016
salivary gland cell autophagic cell death GO:0035071 83 0.016
regulation of establishment of protein localization GO:0070201 61 0.015
localization of cell GO:0051674 257 0.015
regulation of cell differentiation GO:0045595 302 0.015
cellular macromolecule localization GO:0070727 220 0.015
negative regulation of response to stimulus GO:0048585 258 0.015
positive regulation of cellular amine metabolic process GO:0033240 0 0.015
spermatogenesis GO:0007283 200 0.015
mitotic dna integrity checkpoint GO:0044774 75 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.014
response to heat GO:0009408 63 0.014
response to organic cyclic compound GO:0014070 89 0.014
cellular component assembly involved in morphogenesis GO:0010927 151 0.014
response to other organism GO:0051707 293 0.014
aromatic compound catabolic process GO:0019439 166 0.014
secretion by cell GO:0032940 101 0.014
ovarian follicle cell development GO:0030707 248 0.014
spindle assembly GO:0051225 80 0.014
oocyte anterior posterior axis specification GO:0007314 72 0.013
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.013
regulation of protein import into nucleus GO:0042306 28 0.013
regulation of cellular amine metabolic process GO:0033238 3 0.013
female meiotic division GO:0007143 70 0.013
ribonucleoprotein complex biogenesis GO:0022613 31 0.013
central nervous system development GO:0007417 201 0.013
negative regulation of intracellular signal transduction GO:1902532 57 0.013
intrinsic apoptotic signaling pathway GO:0097193 16 0.013
positive regulation of protein metabolic process GO:0051247 128 0.013
embryo development ending in birth or egg hatching GO:0009792 152 0.013
oocyte development GO:0048599 124 0.013
regulation of mitotic sister chromatid segregation GO:0033047 28 0.012
dna damage checkpoint GO:0000077 78 0.012
positive regulation of apoptotic process GO:0043065 47 0.012
oocyte construction GO:0007308 112 0.012
regulation of chromosome segregation GO:0051983 32 0.012
heterochromatin organization GO:0070828 25 0.012
microtubule polymerization or depolymerization GO:0031109 39 0.012
dna dependent dna replication GO:0006261 17 0.012
meiotic nuclear division GO:0007126 151 0.012
positive regulation of catabolic process GO:0009896 105 0.012
protein modification by small protein conjugation GO:0032446 79 0.012
regulation of protein localization GO:0032880 76 0.012
proteolysis GO:0006508 192 0.012
protein catabolic process GO:0030163 101 0.011
nucleotide catabolic process GO:0009166 109 0.011
protein transport GO:0015031 155 0.011
protein localization GO:0008104 284 0.011
germarium derived oocyte fate determination GO:0007294 26 0.011
phosphorylation GO:0016310 294 0.011
enzyme linked receptor protein signaling pathway GO:0007167 179 0.011
positive regulation of phosphorus metabolic process GO:0010562 139 0.011
regulation of sister chromatid cohesion GO:0007063 2 0.011
ribose phosphate metabolic process GO:0019693 145 0.011
regulation of nucleocytoplasmic transport GO:0046822 35 0.011
cell type specific apoptotic process GO:0097285 38 0.011
posttranscriptional regulation of gene expression GO:0010608 145 0.011
regulation of mitotic sister chromatid separation GO:0010965 28 0.011
negative regulation of cell cycle GO:0045786 116 0.011
response to temperature stimulus GO:0009266 106 0.011
positive regulation of growth GO:0045927 75 0.011
cell motility GO:0048870 251 0.010
nucleoside monophosphate metabolic process GO:0009123 52 0.010
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 11 0.010
positive regulation of protein modification process GO:0031401 58 0.010
reproductive system development GO:0061458 74 0.010
regulation of cell proliferation GO:0042127 163 0.010
nitric oxide biosynthetic process GO:0006809 1 0.010
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.010

mrn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.072
cancer DOID:162 0 0.054
organ system cancer DOID:0050686 0 0.031