Drosophila melanogaster

246 known processes

Sos (Dmel_CG7793)

Son of sevenless

(Aliases: dSos,Dmel\CG7793,l(2)k06321,E(sev)2A,sos,2.3,Su(tor)2-2,l(2)Sos,34Ea,Sos1,SOS,E(var)189,CG7793,EY2-3,br24,br25,l(2)34Ea,l(2)k05224,BG:DS00941.4,l(2)br25,l(2)br24,EK2-8,dme-SOS)

Sos biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regionalization GO:0003002 416 0.979
negative regulation of signaling GO:0023057 219 0.960
regulation of cell differentiation GO:0045595 302 0.956
Mouse
regulation of multicellular organismal development GO:2000026 414 0.953
Mouse Worm
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.928
small gtpase mediated signal transduction GO:0007264 88 0.920
embryonic morphogenesis GO:0048598 206 0.878
embryonic pattern specification GO:0009880 174 0.869
tube morphogenesis GO:0035239 191 0.845
positive regulation of macromolecule metabolic process GO:0010604 405 0.844
imaginal disc derived appendage development GO:0048737 399 0.841
macromolecular complex assembly GO:0065003 256 0.835
positive regulation of gene expression GO:0010628 290 0.814
regulation of growth GO:0040008 233 0.813
positive regulation of cellular biosynthetic process GO:0031328 316 0.812
localization of cell GO:0051674 257 0.800
Worm
regulation of cell development GO:0060284 215 0.793
regulation of organelle organization GO:0033043 196 0.792
blastoderm segmentation GO:0007350 159 0.791
positive regulation of ras gtpase activity GO:0032320 36 0.789
developmental growth GO:0048589 280 0.785
periodic partitioning GO:0007365 29 0.782
cellular catabolic process GO:0044248 372 0.756
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.740
segmentation GO:0035282 207 0.726
cell migration GO:0016477 238 0.724
Worm
regulation of neurogenesis GO:0050767 158 0.719
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.710
erbb signaling pathway GO:0038127 58 0.701
establishment of localization in cell GO:0051649 402 0.699
Worm
actin cytoskeleton organization GO:0030036 206 0.690
growth GO:0040007 359 0.678
positive regulation of biosynthetic process GO:0009891 316 0.677
ribonucleoside triphosphate catabolic process GO:0009203 108 0.669
positive regulation of rho gtpase activity GO:0032321 19 0.661
protein complex assembly GO:0006461 200 0.657
photoreceptor cell development GO:0042461 96 0.653
regulation of cellular component biogenesis GO:0044087 201 0.637
positive regulation of rna biosynthetic process GO:1902680 266 0.634
nucleotide metabolic process GO:0009117 161 0.631
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.629
negative regulation of signal transduction GO:0009968 206 0.629
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.612
organonitrogen compound metabolic process GO:1901564 318 0.609
regulation of anatomical structure size GO:0090066 163 0.606
regulation of ras gtpase activity GO:0032318 38 0.603
positive regulation of cellular component organization GO:0051130 156 0.597
positive regulation of transcription dna templated GO:0045893 266 0.592
axon development GO:0061564 297 0.585
positive regulation of nucleic acid templated transcription GO:1903508 266 0.582
post embryonic appendage morphogenesis GO:0035120 385 0.580
photoreceptor cell differentiation GO:0046530 170 0.576
embryo development ending in birth or egg hatching GO:0009792 152 0.547
Worm
carbohydrate derivative catabolic process GO:1901136 118 0.544
imaginal disc derived appendage morphogenesis GO:0035114 395 0.528
gtp catabolic process GO:0006184 72 0.518
positive regulation of response to stimulus GO:0048584 323 0.517
actin filament based process GO:0030029 220 0.515
protein complex biogenesis GO:0070271 201 0.509
regulation of nervous system development GO:0051960 248 0.504
regulation of ras protein signal transduction GO:0046578 93 0.491
segment polarity determination GO:0007367 25 0.491
nucleobase containing small molecule metabolic process GO:0055086 174 0.481
positive regulation of signal transduction GO:0009967 223 0.477
regulation of small gtpase mediated signal transduction GO:0051056 93 0.473
regulation of rho gtpase activity GO:0032319 20 0.468
positive regulation of neurogenesis GO:0050769 41 0.465
negative regulation of cell communication GO:0010648 223 0.452
positive regulation of nucleotide catabolic process GO:0030813 46 0.447
regulation of cytoskeleton organization GO:0051493 89 0.438
ras protein signal transduction GO:0007265 88 0.437
positive regulation of cell communication GO:0010647 250 0.437
imaginal disc derived wing morphogenesis GO:0007476 337 0.436
single organism catabolic process GO:0044712 228 0.432
body morphogenesis GO:0010171 2 0.431
Worm
regulation of intracellular signal transduction GO:1902531 236 0.429
purine containing compound metabolic process GO:0072521 155 0.427
single organism cellular localization GO:1902580 180 0.424
nucleoside metabolic process GO:0009116 127 0.423
cell motility GO:0048870 251 0.420
Worm
appendage morphogenesis GO:0035107 397 0.420
chemotaxis GO:0006935 249 0.415
cellular protein modification process GO:0006464 438 0.413
positive regulation of nervous system development GO:0051962 69 0.411
intracellular transport GO:0046907 228 0.407
programmed cell death GO:0012501 257 0.401
positive regulation of rac gtpase activity GO:0032855 8 0.388
gtp metabolic process GO:0046039 72 0.387
small molecule metabolic process GO:0044281 305 0.378
tissue morphogenesis GO:0048729 297 0.374
cellular protein complex assembly GO:0043623 71 0.374
regulation of cellular catabolic process GO:0031329 157 0.373
catabolic process GO:0009056 409 0.373
sensory organ morphogenesis GO:0090596 260 0.369
appendage development GO:0048736 401 0.368
guanosine containing compound catabolic process GO:1901069 74 0.367
positive regulation of rna metabolic process GO:0051254 271 0.367
cell death GO:0008219 279 0.365
heart development GO:0007507 82 0.364
negative regulation of response to stimulus GO:0048585 258 0.359
regulation of cell cycle GO:0051726 291 0.352
compound eye photoreceptor cell differentiation GO:0001751 140 0.350
epithelial cell development GO:0002064 274 0.348
protein modification process GO:0036211 438 0.347
compound eye development GO:0048749 307 0.346
ribose phosphate metabolic process GO:0019693 145 0.340
eye development GO:0001654 323 0.339
compound eye photoreceptor development GO:0042051 78 0.330
head development GO:0060322 135 0.330
purine ribonucleotide catabolic process GO:0009154 109 0.323
amine metabolic process GO:0009308 12 0.318
regulation of cellular response to stress GO:0080135 89 0.314
epidermal growth factor receptor signaling pathway GO:0007173 58 0.305
cellular macromolecular complex assembly GO:0034622 153 0.303
cellular ketone metabolic process GO:0042180 24 0.298
microtubule based transport GO:0010970 42 0.295
carbohydrate derivative metabolic process GO:1901135 217 0.291
regulation of cell proliferation GO:0042127 163 0.283
Mouse
regulation of programmed cell death GO:0043067 152 0.282
eye photoreceptor cell differentiation GO:0001754 145 0.278
cellular amino acid metabolic process GO:0006520 61 0.275
regulation of photoreceptor cell differentiation GO:0046532 34 0.270
regulation of protein polymerization GO:0032271 28 0.268
purine nucleotide metabolic process GO:0006163 146 0.268
multi organism reproductive behavior GO:0044705 121 0.267
Worm
ribonucleoside triphosphate metabolic process GO:0009199 119 0.266
cognition GO:0050890 141 0.265
compound eye morphogenesis GO:0001745 249 0.264
nucleoside triphosphate metabolic process GO:0009141 120 0.263
regulation of erbb signaling pathway GO:1901184 42 0.263
intracellular signal transduction GO:0035556 300 0.263
carboxylic acid metabolic process GO:0019752 92 0.261
transcription from rna polymerase ii promoter GO:0006366 368 0.260
purine nucleoside metabolic process GO:0042278 127 0.260
death GO:0016265 284 0.257
nucleoside phosphate metabolic process GO:0006753 162 0.254
single organism intracellular transport GO:1902582 207 0.252
positive regulation of cellular component biogenesis GO:0044089 80 0.251
regulation of cellular component size GO:0032535 98 0.238
dorsal ventral axis specification ovarian follicular epithelium GO:0008069 13 0.236
regulation of nucleotide catabolic process GO:0030811 48 0.232
positive regulation of cell differentiation GO:0045597 64 0.230
leg disc development GO:0035218 92 0.228
nucleoside phosphate catabolic process GO:1901292 110 0.225
oxoacid metabolic process GO:0043436 103 0.223
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.218
cellular amine metabolic process GO:0044106 12 0.216
actin polymerization or depolymerization GO:0008154 31 0.215
regulation of protein metabolic process GO:0051246 256 0.214
regulation of protein complex assembly GO:0043254 42 0.212
regulation of apoptotic process GO:0042981 130 0.211
regulation of cellular amino acid metabolic process GO:0006521 0 0.209
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.207
glycosyl compound metabolic process GO:1901657 127 0.205
regulation of response to stress GO:0080134 200 0.204
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.203
positive regulation of cell development GO:0010720 61 0.202
neuron projection guidance GO:0097485 241 0.192
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.192
negative regulation of multicellular organismal process GO:0051241 142 0.189
actin filament polymerization GO:0030041 27 0.189
response to oxidative stress GO:0006979 86 0.187
negative regulation of erbb signaling pathway GO:1901185 29 0.187
purine ribonucleotide metabolic process GO:0009150 145 0.187
regulation of mitotic cell cycle GO:0007346 190 0.185
positive regulation of nucleotide metabolic process GO:0045981 55 0.183
membrane organization GO:0061024 112 0.182
negative regulation of cellular metabolic process GO:0031324 382 0.178
regulation of actin filament length GO:0030832 27 0.177
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 29 0.174
chromosome organization GO:0051276 360 0.173
regulation of actin filament based process GO:0032970 42 0.166
regulation of cellular amine metabolic process GO:0033238 3 0.165
circulatory system development GO:0072359 82 0.165
regulation of cell death GO:0010941 173 0.162
erk1 and erk2 cascade GO:0070371 39 0.158
negative regulation of rna biosynthetic process GO:1902679 240 0.157
cell adhesion GO:0007155 136 0.157
regulation of neuron differentiation GO:0045664 103 0.153
organic hydroxy compound metabolic process GO:1901615 83 0.152
multi organism behavior GO:0051705 175 0.151
Worm
axonogenesis GO:0007409 290 0.148
embryonic axis specification GO:0000578 107 0.145
positive regulation of nucleoside metabolic process GO:0045979 47 0.145
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.144
Mouse
open tracheal system development GO:0007424 204 0.142
tube development GO:0035295 244 0.140
positive regulation of gtpase activity GO:0043547 43 0.139
guanosine containing compound metabolic process GO:1901068 74 0.136
tracheal outgrowth open tracheal system GO:0007426 18 0.135
regulation of cellular ketone metabolic process GO:0010565 3 0.134
wing disc morphogenesis GO:0007472 344 0.134
compound eye photoreceptor fate commitment GO:0001752 36 0.134
protein localization GO:0008104 284 0.133
establishment of organelle localization GO:0051656 122 0.133
negative regulation of rna metabolic process GO:0051253 251 0.132
organic substance catabolic process GO:1901575 308 0.131
apoptotic process GO:0006915 159 0.128
purine nucleoside catabolic process GO:0006152 112 0.127
eye photoreceptor cell fate commitment GO:0042706 37 0.127
cell projection assembly GO:0030031 94 0.127
organophosphate catabolic process GO:0046434 112 0.125
regulation of mapk cascade GO:0043408 92 0.124
purine nucleotide catabolic process GO:0006195 109 0.123
columnar cuboidal epithelial cell development GO:0002066 249 0.123
regulation of nucleotide metabolic process GO:0006140 62 0.122
mitotic spindle organization GO:0007052 220 0.122
regulation of actin polymerization or depolymerization GO:0008064 27 0.121
aging GO:0007568 143 0.119
digestive system development GO:0055123 149 0.118
eye photoreceptor cell development GO:0042462 81 0.118
cellular protein localization GO:0034613 160 0.117
regulation of jnk cascade GO:0046328 40 0.116
regulation of purine nucleotide metabolic process GO:1900542 62 0.115
taxis GO:0042330 304 0.115
positive regulation of photoreceptor cell differentiation GO:0046534 12 0.114
gliogenesis GO:0042063 80 0.114
regulation of phosphorylation GO:0042325 147 0.113
muscle structure development GO:0061061 224 0.113
glycosyl compound catabolic process GO:1901658 112 0.113
purine containing compound catabolic process GO:0072523 112 0.110
r3 r4 cell differentiation GO:0048056 12 0.109
epithelial cell migration GO:0010631 148 0.108
biological adhesion GO:0022610 138 0.108
regulation of nucleoside metabolic process GO:0009118 50 0.108
single organism cell adhesion GO:0098602 47 0.108
immune system process GO:0002376 347 0.107
Mouse
positive regulation of multicellular organismal process GO:0051240 143 0.107
Worm
positive regulation of cell proliferation GO:0008284 47 0.106
organic acid metabolic process GO:0006082 103 0.105
negative regulation of transcription dna templated GO:0045892 237 0.104
regulation of autophagy GO:0010506 62 0.104
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.102
regulation of rho protein signal transduction GO:0035023 20 0.102
positive regulation of cellular amine metabolic process GO:0033240 0 0.100
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.099
regulation of rac protein signal transduction GO:0035020 3 0.098
positive regulation of organelle organization GO:0010638 65 0.097
membrane invagination GO:0010324 11 0.097
enzyme linked receptor protein signaling pathway GO:0007167 179 0.095
Mouse
eye morphogenesis GO:0048592 260 0.094
protein complex disassembly GO:0043241 36 0.094
r7 cell differentiation GO:0045466 43 0.093
vesicle mediated transport GO:0016192 381 0.092
larval development GO:0002164 104 0.091
Worm
negative regulation of cell differentiation GO:0045596 143 0.091
organophosphate metabolic process GO:0019637 195 0.090
reproductive behavior GO:0019098 122 0.089
Worm
positive regulation of protein metabolic process GO:0051247 128 0.089
positive regulation of protein modification process GO:0031401 58 0.089
negative regulation of cell development GO:0010721 62 0.088
purine ribonucleoside metabolic process GO:0046128 127 0.087
actin filament organization GO:0007015 126 0.087
regulation of anatomical structure morphogenesis GO:0022603 242 0.086
autophagy GO:0006914 108 0.085
regulation of purine nucleotide catabolic process GO:0033121 48 0.084
multi multicellular organism process GO:0044706 123 0.084
Worm
regulation of actin filament polymerization GO:0030833 25 0.084
cellular response to endogenous stimulus GO:0071495 80 0.083
Mouse
cellular macromolecule localization GO:0070727 220 0.082
response to nutrient levels GO:0031667 114 0.082
digestive tract morphogenesis GO:0048546 127 0.082
anterior posterior axis specification GO:0009948 109 0.081
tissue migration GO:0090130 155 0.080
maintenance of location GO:0051235 73 0.080
positive regulation of protein complex assembly GO:0031334 22 0.079
signal transduction by phosphorylation GO:0023014 107 0.079
ribonucleoside metabolic process GO:0009119 127 0.078
negative regulation of nucleic acid templated transcription GO:1903507 240 0.078
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.077
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.077
regulation of localization GO:0032879 275 0.075
epithelial cell differentiation GO:0030855 322 0.075
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.075
forebrain development GO:0030900 2 0.073
response to endogenous stimulus GO:0009719 119 0.073
Mouse
regulation of cellular component movement GO:0051270 42 0.072
aromatic compound catabolic process GO:0019439 166 0.071
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.071
protein polymerization GO:0051258 42 0.071
mapk cascade GO:0000165 107 0.071
establishment or maintenance of cell polarity GO:0007163 167 0.071
response to organonitrogen compound GO:0010243 75 0.071
ameboidal type cell migration GO:0001667 151 0.070
anterior posterior pattern specification GO:0009952 136 0.069
hemopoiesis GO:0030097 46 0.069
Mouse
regulation of gtp catabolic process GO:0033124 44 0.069
intraciliary transport GO:0042073 8 0.068
hemocyte differentiation GO:0042386 38 0.068
establishment of mitotic spindle orientation GO:0000132 13 0.067
positive regulation of cellular protein metabolic process GO:0032270 118 0.067
pigment metabolic process GO:0042440 84 0.067
axis specification GO:0009798 167 0.066
regulation of axonogenesis GO:0050770 32 0.065
positive regulation of cell adhesion GO:0045785 10 0.065
imaginal disc derived wing vein specification GO:0007474 48 0.063
peptidyl tyrosine modification GO:0018212 24 0.063
positive regulation of cytoskeleton organization GO:0051495 21 0.063
wnt signaling pathway GO:0016055 98 0.061
negative regulation of erk1 and erk2 cascade GO:0070373 3 0.061
positive regulation of signaling GO:0023056 243 0.061
negative regulation of apoptotic process GO:0043066 63 0.061
regulation of actin cytoskeleton organization GO:0032956 42 0.060
phosphorylation GO:0016310 294 0.060
negative regulation of cell cycle GO:0045786 116 0.059
regulation of transferase activity GO:0051338 58 0.058
regulation of cell projection organization GO:0031344 92 0.058
imaginal disc derived leg morphogenesis GO:0007480 80 0.058
response to oxygen containing compound GO:1901700 200 0.057
organelle localization GO:0051640 148 0.057
torc1 signaling GO:0038202 12 0.057
purine nucleoside triphosphate metabolic process GO:0009144 119 0.057
telencephalon development GO:0021537 2 0.056
cell fate specification GO:0001708 71 0.056
negative regulation of neurogenesis GO:0050768 53 0.055
cytoskeleton dependent intracellular transport GO:0030705 44 0.055
nuclear division GO:0000280 332 0.055
cell cycle g1 s phase transition GO:0044843 31 0.054
response to hormone GO:0009725 45 0.054
regulation of immune system process GO:0002682 176 0.053
Mouse
neuron fate commitment GO:0048663 50 0.053
nucleoside catabolic process GO:0009164 112 0.053
nucleocytoplasmic transport GO:0006913 72 0.053
regulation of chromosome organization GO:0033044 64 0.052
mitotic cell cycle phase transition GO:0044772 138 0.052
cell proliferation GO:0008283 299 0.052
Mouse
endodermal cell fate commitment GO:0001711 3 0.051
positive regulation of neuron differentiation GO:0045666 26 0.050
stress activated mapk cascade GO:0051403 52 0.050
ribonucleotide metabolic process GO:0009259 145 0.050
dorsal ventral axis specification GO:0009950 66 0.050
nucleobase containing compound catabolic process GO:0034655 165 0.049
rac protein signal transduction GO:0016601 3 0.049
cellular nitrogen compound catabolic process GO:0044270 165 0.049
positive regulation of gtp catabolic process GO:0033126 43 0.049
establishment of mitotic spindle localization GO:0040001 17 0.048
spermatogenesis GO:0007283 200 0.048
apoptotic signaling pathway GO:0097190 27 0.047
nucleotide catabolic process GO:0009166 109 0.047
regulation of compound eye photoreceptor development GO:0045314 12 0.046
regulation of molecular function GO:0065009 217 0.046
positive regulation of protein polymerization GO:0032273 14 0.046
neuron migration GO:0001764 5 0.046
mushroom body development GO:0016319 70 0.046
jnk cascade GO:0007254 50 0.045
developmental programmed cell death GO:0010623 138 0.045
regulation of notch signaling pathway GO:0008593 100 0.045
cell growth GO:0016049 108 0.045
axon guidance GO:0007411 233 0.042
regulation of chromatin silencing GO:0031935 36 0.042
determination of adult lifespan GO:0008340 137 0.041
negative regulation of epithelial cell proliferation GO:0050680 4 0.041
stem cell development GO:0048864 79 0.041
dna metabolic process GO:0006259 227 0.040
rho protein signal transduction GO:0007266 14 0.040
regulation of intracellular transport GO:0032386 64 0.040
negative regulation of intracellular signal transduction GO:1902532 57 0.039
lipid localization GO:0010876 54 0.039
cytoplasmic transport GO:0016482 130 0.039
negative regulation of mapk cascade GO:0043409 23 0.038
multicellular organismal aging GO:0010259 140 0.038
response to alcohol GO:0097305 95 0.038
cellular response to organonitrogen compound GO:0071417 36 0.038
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.038
neuroblast differentiation GO:0014016 29 0.038
morphogenesis of an epithelium GO:0002009 276 0.038
anterior posterior axis specification embryo GO:0008595 103 0.038
gastrulation GO:0007369 70 0.038
purine nucleoside triphosphate catabolic process GO:0009146 108 0.037
single organismal cell cell adhesion GO:0016337 45 0.037
meiotic cell cycle process GO:1903046 132 0.037
eggshell formation GO:0030703 105 0.037
r7 cell fate commitment GO:0007465 12 0.037
g protein coupled receptor signaling pathway GO:0007186 136 0.037
male gamete generation GO:0048232 201 0.036
phagocytosis GO:0006909 215 0.036
regulation of cellular protein metabolic process GO:0032268 243 0.035
response to biotic stimulus GO:0009607 294 0.035
regulation of phosphorus metabolic process GO:0051174 210 0.035
response to external biotic stimulus GO:0043207 293 0.035
digestive tract development GO:0048565 149 0.035
neuroblast fate commitment GO:0014017 19 0.034
ribonucleotide catabolic process GO:0009261 109 0.034
organonitrogen compound catabolic process GO:1901565 128 0.034
cellular response to dna damage stimulus GO:0006974 223 0.034
brain development GO:0007420 120 0.034
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.033
protein catabolic process GO:0030163 101 0.033
cellular response to chemical stimulus GO:0070887 199 0.033
Mouse
regulation of protein localization GO:0032880 76 0.033
positive regulation of phosphate metabolic process GO:0045937 139 0.032
positive regulation of hydrolase activity GO:0051345 78 0.032
notch signaling pathway GO:0007219 120 0.032
negative regulation of biosynthetic process GO:0009890 277 0.032
learning or memory GO:0007611 141 0.031
intracellular protein transport GO:0006886 104 0.031
hematopoietic or lymphoid organ development GO:0048534 57 0.031
Mouse
negative regulation of programmed cell death GO:0043069 72 0.031
positive regulation of cellular catabolic process GO:0031331 95 0.031
organelle assembly GO:0070925 198 0.030
organonitrogen compound biosynthetic process GO:1901566 117 0.030
response to nitrogen compound GO:1901698 90 0.030
negative regulation of developmental process GO:0051093 201 0.030
negative regulation of phosphorylation GO:0042326 35 0.030
negative regulation of cell proliferation GO:0008285 69 0.030
maintenance of protein location GO:0045185 28 0.030
regulation of organ growth GO:0046620 42 0.030
regulation of cell adhesion GO:0030155 27 0.030
cilium morphogenesis GO:0060271 39 0.029
establishment of spindle orientation GO:0051294 18 0.029
spermatid differentiation GO:0048515 114 0.029
dendrite development GO:0016358 204 0.028
regulation of dna templated transcription elongation GO:0032784 17 0.028
regulation of phosphate metabolic process GO:0019220 210 0.028
response to peptide hormone GO:0043434 29 0.028
negative regulation of protein phosphorylation GO:0001933 17 0.027
regulation of microtubule based process GO:0032886 49 0.027
negative regulation of growth GO:0045926 84 0.026
regulation of protein kinase activity GO:0045859 51 0.026
negative regulation of response to extracellular stimulus GO:0032105 6 0.026
dorsal ventral pattern formation GO:0009953 133 0.026
positive regulation of apoptotic process GO:0043065 47 0.026
negative regulation of cellular biosynthetic process GO:0031327 277 0.025
gland development GO:0048732 191 0.025
response to lipid GO:0033993 38 0.025
embryonic organ development GO:0048568 50 0.025
regulation of hemocyte proliferation GO:0035206 37 0.025
positive regulation of mapk cascade GO:0043410 63 0.025
male gonad development GO:0008584 9 0.025
positive regulation of intracellular signal transduction GO:1902533 116 0.025
carbohydrate derivative biosynthetic process GO:1901137 85 0.025
regulation of cytoplasmic transport GO:1903649 47 0.025
maintenance of location in cell GO:0051651 28 0.025
negative regulation of epithelial cell migration GO:0010633 1 0.025
response to organic substance GO:0010033 284 0.024
Mouse
cell cycle phase transition GO:0044770 140 0.024
regulation of protein modification process GO:0031399 112 0.024
negative regulation of gene expression GO:0010629 387 0.024
sex differentiation GO:0007548 81 0.024
nucleoside triphosphate catabolic process GO:0009143 108 0.024
establishment of spindle localization GO:0051293 22 0.023
organic cyclic compound catabolic process GO:1901361 168 0.023
positive regulation of phosphorylation GO:0042327 87 0.023
protein acetylation GO:0006473 39 0.023
extrinsic apoptotic signaling pathway GO:0097191 1 0.023
regulation of hippo signaling GO:0035330 14 0.023
immune response GO:0006955 246 0.023
spindle organization GO:0007051 253 0.023
organic substance transport GO:0071702 257 0.022
protein acylation GO:0043543 42 0.022
eggshell chorion assembly GO:0007306 66 0.022
mating GO:0007618 120 0.022
negative regulation of cell death GO:0060548 81 0.022
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.022
locomotory behavior GO:0007626 176 0.022
positive regulation of molecular function GO:0044093 136 0.022
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.021
antimicrobial humoral response GO:0019730 99 0.021
endocytosis GO:0006897 310 0.021
regulation of gtpase activity GO:0043087 44 0.021
epithelium migration GO:0090132 148 0.021
regulation of catabolic process GO:0009894 170 0.021
chromatin modification GO:0016568 147 0.021
positive regulation of cell death GO:0010942 69 0.021
learning GO:0007612 75 0.021
regulation of neuroblast proliferation GO:1902692 34 0.020
histone modification GO:0016570 106 0.020
developmental growth involved in morphogenesis GO:0060560 65 0.020
regulation of cell migration GO:0030334 22 0.020
ribonucleoside catabolic process GO:0042454 112 0.020
regulation of gene silencing GO:0060968 63 0.020
response to other organism GO:0051707 293 0.020
modification dependent macromolecule catabolic process GO:0043632 79 0.020
lipid metabolic process GO:0006629 121 0.020
heterocycle catabolic process GO:0046700 166 0.020
torso signaling pathway GO:0008293 21 0.020
maintenance of protein location in cell GO:0032507 26 0.019
positive regulation of erk1 and erk2 cascade GO:0070374 36 0.019
actomyosin structure organization GO:0031032 56 0.019
regulation of organ morphogenesis GO:2000027 78 0.019
morphogenesis of follicular epithelium GO:0016333 36 0.019
regulation of developmental growth GO:0048638 174 0.019
negative regulation of neuroblast proliferation GO:0007406 27 0.019
immune effector process GO:0002252 98 0.019
hindbrain development GO:0030902 2 0.019
larval lymph gland hemopoiesis GO:0035167 17 0.019
spindle localization GO:0051653 22 0.018
glial cell migration GO:0008347 31 0.018
establishment of protein localization to organelle GO:0072594 62 0.018
positive regulation of actin filament polymerization GO:0030838 11 0.018

Sos disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.106
cancer DOID:162 0 0.082
disease of cellular proliferation DOID:14566 0 0.082
organ system cancer DOID:0050686 0 0.082
cardiovascular system disease DOID:1287 0 0.029