Drosophila melanogaster

110 known processes

MED17 (Dmel_CG7957)

Mediator complex subunit 17

(Aliases: p70,Dmel\CG7957,CG7957,Med17,Trap80,dTRAP80/SRB4,dTRAP80,l(3)s2956,dTrap80,TRAP80)

MED17 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
transcription from rna polymerase ii promoter GO:0006366 368 0.982
positive regulation of transcription dna templated GO:0045893 266 0.958
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.876
mitotic g2 m transition checkpoint GO:0044818 70 0.847
negative regulation of cell cycle phase transition GO:1901988 103 0.784
positive regulation of nucleic acid templated transcription GO:1903508 266 0.684
cellular response to dna damage stimulus GO:0006974 223 0.647
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.642
cell proliferation GO:0008283 299 0.637
positive regulation of cellular biosynthetic process GO:0031328 316 0.630
positive regulation of rna metabolic process GO:0051254 271 0.567
negative regulation of mitotic cell cycle GO:0045930 109 0.524
mitotic dna integrity checkpoint GO:0044774 75 0.521
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.518
mitotic dna damage checkpoint GO:0044773 74 0.502
immune system process GO:0002376 347 0.494
positive regulation of macromolecule metabolic process GO:0010604 405 0.431
negative regulation of developmental process GO:0051093 201 0.421
mitotic g2 dna damage checkpoint GO:0007095 69 0.411
negative regulation of cell cycle process GO:0010948 109 0.398
g2 dna damage checkpoint GO:0031572 69 0.377
neural precursor cell proliferation GO:0061351 75 0.375
dna damage checkpoint GO:0000077 78 0.363
cell division GO:0051301 248 0.351
negative regulation of cell cycle GO:0045786 116 0.349
cell cycle phase transition GO:0044770 140 0.334
regulation of cell proliferation GO:0042127 163 0.327
positive regulation of gene expression GO:0010628 290 0.320
regulation of cell cycle process GO:0010564 181 0.318
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.284
regulation of cell cycle GO:0051726 291 0.280
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.272
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.257
response to other organism GO:0051707 293 0.252
positive regulation of biosynthetic process GO:0009891 316 0.243
regionalization GO:0003002 416 0.240
immune response GO:0006955 246 0.230
regulation of cell differentiation GO:0045595 302 0.211
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.204
negative regulation of cell differentiation GO:0045596 143 0.203
negative regulation of rna biosynthetic process GO:1902679 240 0.202
phosphorylation GO:0016310 294 0.200
taxis GO:0042330 304 0.190
mrna metabolic process GO:0016071 124 0.182
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.173
response to biotic stimulus GO:0009607 294 0.173
regulation of immune system process GO:0002682 176 0.170
regulation of immune response GO:0050776 118 0.166
regulation of cell cycle phase transition GO:1901987 130 0.164
chromatin organization GO:0006325 207 0.162
mrna polyadenylation GO:0006378 11 0.159
response to external biotic stimulus GO:0043207 293 0.159
neuroblast proliferation GO:0007405 74 0.158
growth GO:0040007 359 0.158
response to lipopolysaccharide GO:0032496 4 0.153
protein complex biogenesis GO:0070271 201 0.149
spermatogenesis GO:0007283 200 0.147
regulation of notch signaling pathway GO:0008593 100 0.144
stem cell differentiation GO:0048863 117 0.142
anterior posterior pattern specification GO:0009952 136 0.141
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.139
nuclear division GO:0000280 332 0.139
rna polyadenylation GO:0043631 12 0.139
positive regulation of rna biosynthetic process GO:1902680 266 0.138
transcription initiation from rna polymerase ii promoter GO:0006367 25 0.137
Human
posttranscriptional gene silencing by rna GO:0035194 45 0.133
regulation of mitotic cell cycle GO:0007346 190 0.125
cellular protein localization GO:0034613 160 0.124
organelle fission GO:0048285 340 0.124
protein dna complex subunit organization GO:0071824 86 0.120
stem cell maintenance GO:0019827 67 0.120
dna repair GO:0006281 54 0.119
gliogenesis GO:0042063 80 0.116
mitotic cell cycle phase transition GO:0044772 138 0.115
single organism cellular localization GO:1902580 180 0.114
regulation of cell development GO:0060284 215 0.114
mitotic cell cycle checkpoint GO:0007093 88 0.112
negative regulation of nucleic acid templated transcription GO:1903507 240 0.110
regulation of neurogenesis GO:0050767 158 0.110
regulation of neural precursor cell proliferation GO:2000177 35 0.107
rna 3 end processing GO:0031123 45 0.101
embryo development ending in birth or egg hatching GO:0009792 152 0.099
chromatin modification GO:0016568 147 0.096
negative regulation of neuroblast proliferation GO:0007406 27 0.093
male gamete generation GO:0048232 201 0.091
organic substance transport GO:0071702 257 0.091
body morphogenesis GO:0010171 2 0.090
mrna processing GO:0006397 104 0.089
golgi to plasma membrane transport GO:0006893 8 0.087
regulation of multi organism process GO:0043900 131 0.086
negative regulation of transcription dna templated GO:0045892 237 0.086
regulation of mitotic cell cycle phase transition GO:1901990 130 0.085
dna integrity checkpoint GO:0031570 81 0.085
protein localization GO:0008104 284 0.084
negative regulation of rna metabolic process GO:0051253 251 0.084
cell cycle checkpoint GO:0000075 95 0.083
carbohydrate derivative metabolic process GO:1901135 217 0.081
regulation of response to stress GO:0080134 200 0.081
cell migration GO:0016477 238 0.080
compound eye development GO:0048749 307 0.078
snrna 3 end processing GO:0034472 14 0.078
gene silencing GO:0016458 138 0.075
phagocytosis GO:0006909 215 0.074
posttranscriptional regulation of gene expression GO:0010608 145 0.073
ameboidal type cell migration GO:0001667 151 0.072
regulation of multicellular organismal development GO:2000026 414 0.072
negative regulation of cell proliferation GO:0008285 69 0.070
negative regulation of biosynthetic process GO:0009890 277 0.068
segmentation GO:0035282 207 0.067
blastoderm segmentation GO:0007350 159 0.066
notch signaling pathway GO:0007219 120 0.064
compound eye morphogenesis GO:0001745 249 0.063
response to radiation GO:0009314 155 0.061
single organism intracellular transport GO:1902582 207 0.061
intracellular protein transport GO:0006886 104 0.061
stem cell development GO:0048864 79 0.060
chromosome organization GO:0051276 360 0.059
regulation of cellular ketone metabolic process GO:0010565 3 0.059
stem cell proliferation GO:0072089 88 0.059
macromolecular complex assembly GO:0065003 256 0.058
protein complex assembly GO:0006461 200 0.058
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.056
negative regulation of cellular biosynthetic process GO:0031327 277 0.055
response to bacterium GO:0009617 198 0.055
negative regulation of multicellular organismal process GO:0051241 142 0.053
cell cycle g1 s phase transition GO:0044843 31 0.053
snrna metabolic process GO:0016073 14 0.052
central nervous system development GO:0007417 201 0.051
positive regulation of multicellular organismal process GO:0051240 143 0.051
localization of cell GO:0051674 257 0.050
negative regulation of cellular metabolic process GO:0031324 382 0.050
embryonic morphogenesis GO:0048598 206 0.049
tube development GO:0035295 244 0.049
negative regulation of neural precursor cell proliferation GO:2000178 27 0.049
regulation of cellular amino acid metabolic process GO:0006521 0 0.048
dna templated transcription initiation GO:0006352 25 0.048
Human
g1 s transition of mitotic cell cycle GO:0000082 31 0.047
dna metabolic process GO:0006259 227 0.047
compound eye photoreceptor cell differentiation GO:0001751 140 0.045
response to abiotic stimulus GO:0009628 341 0.045
mrna 3 end processing GO:0031124 28 0.045
response to organic substance GO:0010033 284 0.043
positive regulation of cell proliferation GO:0008284 47 0.042
negative regulation of stem cell proliferation GO:2000647 30 0.042
organonitrogen compound metabolic process GO:1901564 318 0.042
regulation of chromatin organization GO:1902275 32 0.042
peptidyl amino acid modification GO:0018193 105 0.041
histone modification GO:0016570 106 0.041
protein phosphorylation GO:0006468 169 0.041
meiosis i GO:0007127 59 0.041
cell motility GO:0048870 251 0.041
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.041
smoothened signaling pathway GO:0007224 49 0.040
regulation of nervous system development GO:0051960 248 0.040
establishment of localization in cell GO:0051649 402 0.039
muscle organ development GO:0007517 127 0.039
negative regulation of nervous system development GO:0051961 92 0.039
regulation of cellular localization GO:0060341 136 0.039
endocytosis GO:0006897 310 0.039
positive regulation of response to stimulus GO:0048584 323 0.039
protein deubiquitination GO:0016579 17 0.038
dendrite development GO:0016358 204 0.038
dna templated transcription elongation GO:0006354 18 0.038
regulation of phosphate metabolic process GO:0019220 210 0.038
negative regulation of gene expression GO:0010629 387 0.037
regulation of neuroblast proliferation GO:1902692 34 0.037
larval development GO:0002164 104 0.037
positive regulation of developmental process GO:0051094 143 0.037
appendage development GO:0048736 401 0.037
epithelium migration GO:0090132 148 0.037
rna processing GO:0006396 147 0.036
anterior posterior axis specification embryo GO:0008595 103 0.036
positive regulation of signaling GO:0023056 243 0.036
positive regulation of cellular protein metabolic process GO:0032270 118 0.036
spinal cord development GO:0021510 1 0.036
tissue migration GO:0090130 155 0.036
humoral immune response GO:0006959 117 0.035
neuron projection guidance GO:0097485 241 0.035
cytoplasmic transport GO:0016482 130 0.035
muscle structure development GO:0061061 224 0.035
chemotaxis GO:0006935 249 0.035
camera type eye development GO:0043010 4 0.035
developmental growth GO:0048589 280 0.034
mitotic nuclear division GO:0007067 213 0.034
organic substance catabolic process GO:1901575 308 0.034
epithelial cell migration GO:0010631 148 0.033
positive regulation of cellular component organization GO:0051130 156 0.033
regulation of gene expression epigenetic GO:0040029 128 0.033
regulation of stem cell proliferation GO:0072091 40 0.033
dendrite morphogenesis GO:0048813 199 0.032
posttranscriptional gene silencing GO:0016441 46 0.032
positive regulation of protein complex assembly GO:0031334 22 0.032
peptidyl lysine acetylation GO:0018394 39 0.032
tissue morphogenesis GO:0048729 297 0.032
phosphorylation of rna polymerase ii c terminal domain GO:0070816 1 0.032
proteolysis GO:0006508 192 0.032
intracellular transport GO:0046907 228 0.031
positive regulation of signal transduction GO:0009967 223 0.031
histone mrna metabolic process GO:0008334 8 0.031
response to oxygen containing compound GO:1901700 200 0.031
snrna processing GO:0016180 14 0.031
anterior posterior axis specification GO:0009948 109 0.030
stem cell division GO:0017145 69 0.030
vesicle mediated transport GO:0016192 381 0.030
small molecule metabolic process GO:0044281 305 0.030
regulation of cellular protein metabolic process GO:0032268 243 0.030
telencephalon development GO:0021537 2 0.029
protein acylation GO:0043543 42 0.029
embryonic pattern specification GO:0009880 174 0.029
meiotic nuclear division GO:0007126 151 0.029
defense response to gram negative bacterium GO:0050829 94 0.029
homeostatic process GO:0042592 199 0.029
ncrna 3 end processing GO:0043628 17 0.028
cellular ketone metabolic process GO:0042180 24 0.028
regulation of developmental growth GO:0048638 174 0.028
spermatid differentiation GO:0048515 114 0.028
positive regulation of cell communication GO:0010647 250 0.028
positive regulation of developmental growth GO:0048639 62 0.027
eye photoreceptor cell development GO:0042462 81 0.026
defense response GO:0006952 300 0.026
cellular response to lipopolysaccharide GO:0071222 3 0.026
ubiquitin dependent protein catabolic process GO:0006511 78 0.025
cell death GO:0008219 279 0.025
photoreceptor cell differentiation GO:0046530 170 0.025
positive regulation of cellular component biogenesis GO:0044089 80 0.025
imaginal disc derived appendage development GO:0048737 399 0.024
chromatin assembly or disassembly GO:0006333 52 0.024
regulation of intracellular signal transduction GO:1902531 236 0.024
macromolecule catabolic process GO:0009057 161 0.024
rna splicing via transesterification reactions GO:0000375 73 0.023
protein transport GO:0015031 155 0.023
cellular response to organic substance GO:0071310 132 0.023
establishment or maintenance of cell polarity GO:0007163 167 0.023
gene silencing by rna GO:0031047 57 0.023
axon guidance GO:0007411 233 0.023
death GO:0016265 284 0.023
eye development GO:0001654 323 0.023
meiotic cell cycle GO:0051321 171 0.023
axis specification GO:0009798 167 0.022
tripartite regional subdivision GO:0007351 103 0.022
regulation of protein complex assembly GO:0043254 42 0.022
cellular response to biotic stimulus GO:0071216 4 0.022
covalent chromatin modification GO:0016569 106 0.022
production of molecular mediator of immune response GO:0002440 46 0.022
chromatin remodeling GO:0006338 72 0.022
wnt signaling pathway GO:0016055 98 0.022
regulation of chromosome organization GO:0033044 64 0.022
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.022
protein targeting to nucleus GO:0044744 51 0.021
response to ketone GO:1901654 34 0.021
regulation of cell death GO:0010941 173 0.021
cellular protein modification process GO:0006464 438 0.021
organonitrogen compound catabolic process GO:1901565 128 0.021
negative regulation of response to stimulus GO:0048585 258 0.020
cell fate determination GO:0001709 91 0.020
developmental maturation GO:0021700 172 0.020
carboxylic acid metabolic process GO:0019752 92 0.020
positive regulation of protein metabolic process GO:0051247 128 0.020
antimicrobial humoral response GO:0019730 99 0.020
defense response to other organism GO:0098542 225 0.020
response to light stimulus GO:0009416 124 0.020
cellular macromolecule catabolic process GO:0044265 136 0.020
regulation of mrna processing GO:0050684 71 0.019
negative regulation of g1 s transition of mitotic cell cycle GO:2000134 13 0.019
regulation of dna templated transcription elongation GO:0032784 17 0.019
regulation of cellular amine metabolic process GO:0033238 3 0.019
ncrna metabolic process GO:0034660 43 0.019
cellular response to chemical stimulus GO:0070887 199 0.019
gastrulation GO:0007369 70 0.019
regulation of transport GO:0051049 181 0.019
establishment of protein localization to organelle GO:0072594 62 0.019
oocyte development GO:0048599 124 0.019
regulation of response to external stimulus GO:0032101 115 0.018
cellular macromolecule localization GO:0070727 220 0.018
amine metabolic process GO:0009308 12 0.018
protein catabolic process GO:0030163 101 0.018
regulation of protein modification process GO:0031399 112 0.018
protein ubiquitination GO:0016567 70 0.018
imaginal disc derived wing morphogenesis GO:0007476 337 0.018
regulation of apoptotic process GO:0042981 130 0.018
regulation of meiosis GO:0040020 3 0.018
negative regulation of apoptotic process GO:0043066 63 0.017
regulation of mrna metabolic process GO:1903311 72 0.017
meiotic cell cycle process GO:1903046 132 0.017
regulation of humoral immune response GO:0002920 51 0.017
signal transduction in response to dna damage GO:0042770 3 0.017
regulation of intracellular transport GO:0032386 64 0.017
epithelial cell differentiation GO:0030855 322 0.017
somatic stem cell division GO:0048103 37 0.017
nucleoside monophosphate metabolic process GO:0009123 52 0.017
response to organic cyclic compound GO:0014070 89 0.017
negative regulation of cell cycle g1 s phase transition GO:1902807 13 0.017
regulation of localization GO:0032879 275 0.017
protein localization to nucleus GO:0034504 55 0.017
biological adhesion GO:0022610 138 0.017
eye morphogenesis GO:0048592 260 0.017
leg disc morphogenesis GO:0007478 80 0.016
spindle organization GO:0007051 253 0.016
regulation of cellular component biogenesis GO:0044087 201 0.016
digestive tract morphogenesis GO:0048546 127 0.016
axonogenesis GO:0007409 290 0.016
protein localization to organelle GO:0033365 82 0.016
regulation of g1 s transition of mitotic cell cycle GO:2000045 23 0.015
regulation of cytoplasmic transport GO:1903649 47 0.015
aging GO:0007568 143 0.015
autophagy GO:0006914 108 0.015
response to heat GO:0009408 63 0.015
morphogenesis of an epithelium GO:0002009 276 0.015
regulation of gene silencing GO:0060968 63 0.015
regulation of phosphorus metabolic process GO:0051174 210 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.015
internal protein amino acid acetylation GO:0006475 38 0.015
cellular response to molecule of bacterial origin GO:0071219 3 0.015
sensory organ morphogenesis GO:0090596 260 0.015
proteasomal protein catabolic process GO:0010498 59 0.015
cellular amide metabolic process GO:0043603 80 0.015
negative regulation of cell communication GO:0010648 223 0.015
cellular protein complex assembly GO:0043623 71 0.015
positive regulation of protein modification process GO:0031401 58 0.015
establishment of protein localization GO:0045184 163 0.015
cell maturation GO:0048469 144 0.014
positive regulation of cell differentiation GO:0045597 64 0.014
innate immune response GO:0045087 144 0.014
positive regulation of molecular function GO:0044093 136 0.014
cell adhesion GO:0007155 136 0.014
protein modification process GO:0036211 438 0.014
modification dependent protein catabolic process GO:0019941 78 0.014
membrane organization GO:0061024 112 0.014
cellular nitrogen compound catabolic process GO:0044270 165 0.014
positive regulation of cell cycle GO:0045787 43 0.014
regulation of cellular response to stress GO:0080135 89 0.014
response to temperature stimulus GO:0009266 106 0.014
protein acetylation GO:0006473 39 0.014
regulation of smoothened signaling pathway GO:0008589 28 0.013
regulation of wnt signaling pathway GO:0030111 68 0.013
modification dependent macromolecule catabolic process GO:0043632 79 0.013
negative regulation of signal transduction GO:0009968 206 0.013
regulation of cell cycle g1 s phase transition GO:1902806 23 0.013
retina development in camera type eye GO:0060041 4 0.013
regulation of histone modification GO:0031056 20 0.013
ribonucleoside monophosphate catabolic process GO:0009158 39 0.013
protein maturation GO:0051604 71 0.013
positive regulation of immune system process GO:0002684 68 0.013
multicellular organism growth GO:0035264 46 0.013
protein modification by small protein conjugation or removal GO:0070647 106 0.013
peptide metabolic process GO:0006518 80 0.013
embryonic axis specification GO:0000578 107 0.013
cellular macromolecular complex assembly GO:0034622 153 0.013
photoreceptor cell development GO:0042461 96 0.013
eye photoreceptor cell differentiation GO:0001754 145 0.013
programmed cell death GO:0012501 257 0.013
peptidyl lysine modification GO:0018205 57 0.012
protein import GO:0017038 55 0.012
purine nucleoside monophosphate metabolic process GO:0009126 50 0.012
cellular catabolic process GO:0044248 372 0.012
single organism membrane organization GO:0044802 93 0.012
neuronal stem cell division GO:0036445 35 0.012
mitotic recombination GO:0006312 2 0.012
imaginal disc derived appendage morphogenesis GO:0035114 395 0.012
golgi to plasma membrane protein transport GO:0043001 8 0.012
positive regulation of apoptotic signaling pathway GO:2001235 4 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.012
axon development GO:0061564 297 0.012
negative regulation of signaling GO:0023057 219 0.012
post embryonic appendage morphogenesis GO:0035120 385 0.012
negative regulation of cell development GO:0010721 62 0.012
positive regulation of cell migration GO:0030335 2 0.012
nitrogen compound transport GO:0071705 85 0.012
regulation of phosphorylation GO:0042325 147 0.012
endomembrane system organization GO:0010256 119 0.012
regulation of response to dna damage stimulus GO:2001020 23 0.012
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
dna recombination GO:0006310 32 0.011
regulation of molecular function GO:0065009 217 0.011
jak stat cascade GO:0007259 49 0.011
histone h3 k4 methylation GO:0051568 16 0.011
ribonucleoside metabolic process GO:0009119 127 0.011
nuclear import GO:0051170 51 0.011
nuclear transport GO:0051169 72 0.011
dna conformation change GO:0071103 105 0.011
negative regulation of neurogenesis GO:0050768 53 0.011
epithelial tube morphogenesis GO:0060562 88 0.011
salivary gland development GO:0007431 162 0.011
asymmetric cell division GO:0008356 37 0.011
tube morphogenesis GO:0035239 191 0.011
response to extracellular stimulus GO:0009991 116 0.011
immune effector process GO:0002252 98 0.011
regulation of protein metabolic process GO:0051246 256 0.011
regulation of organelle organization GO:0033043 196 0.011
appendage morphogenesis GO:0035107 397 0.011
apoptotic process GO:0006915 159 0.011
protein modification by small protein removal GO:0070646 28 0.011
positive regulation of cell development GO:0010720 61 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.011
intracellular signal transduction GO:0035556 300 0.011
positive regulation of phosphorus metabolic process GO:0010562 139 0.011
nucleoside phosphate metabolic process GO:0006753 162 0.010
transcription elongation from rna polymerase ii promoter GO:0006368 18 0.010
cell fate specification GO:0001708 71 0.010
cellular amino acid metabolic process GO:0006520 61 0.010
regulation of catalytic activity GO:0050790 185 0.010
camera type eye morphogenesis GO:0048593 2 0.010
mapk cascade GO:0000165 107 0.010
carbohydrate metabolic process GO:0005975 82 0.010

MED17 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.153
nervous system disease DOID:863 0 0.019
central nervous system disease DOID:331 0 0.010