Drosophila melanogaster

82 known processes

Ac76E (Dmel_CG7978)

Adenylyl cyclase 76E

(Aliases: CG7978,Dmel\CG7978,DAC76E,ac76e,AC 76E,DAC2)

Ac76E biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cyclic nucleotide biosynthetic process GO:0009190 25 0.220
camp biosynthetic process GO:0006171 17 0.182
single organism behavior GO:0044708 391 0.100
Fly
organophosphate biosynthetic process GO:0090407 46 0.086
response to organic substance GO:0010033 284 0.074
Human Fly
purine ribonucleotide biosynthetic process GO:0009152 28 0.072
carboxylic acid metabolic process GO:0019752 92 0.071
organophosphate metabolic process GO:0019637 195 0.067
carbohydrate derivative biosynthetic process GO:1901137 85 0.066
organonitrogen compound metabolic process GO:1901564 318 0.064
response to ethanol GO:0045471 59 0.060
Human Fly
growth GO:0040007 359 0.059
organonitrogen compound biosynthetic process GO:1901566 117 0.058
neurological system process GO:0050877 358 0.055
Fly
small molecule metabolic process GO:0044281 305 0.053
single organism biosynthetic process GO:0044711 206 0.050
catabolic process GO:0009056 409 0.048
chaeta development GO:0022416 97 0.045
Fly
purine containing compound biosynthetic process GO:0072522 30 0.044
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.044
cyclic nucleotide metabolic process GO:0009187 28 0.040
regionalization GO:0003002 416 0.038
purine nucleotide metabolic process GO:0006163 146 0.038
response to nutrient levels GO:0031667 114 0.037
body morphogenesis GO:0010171 2 0.037
vesicle mediated transport GO:0016192 381 0.036
ribose phosphate metabolic process GO:0019693 145 0.035
developmental growth GO:0048589 280 0.035
neuron projection guidance GO:0097485 241 0.035
chemotaxis GO:0006935 249 0.034
negative regulation of cellular metabolic process GO:0031324 382 0.034
oxoacid metabolic process GO:0043436 103 0.033
phosphorylation GO:0016310 294 0.033
response to endogenous stimulus GO:0009719 119 0.033
Fly
ribose phosphate biosynthetic process GO:0046390 28 0.032
cellular macromolecular complex assembly GO:0034622 153 0.031
post embryonic appendage morphogenesis GO:0035120 385 0.031
cell proliferation GO:0008283 299 0.031
response to oxygen containing compound GO:1901700 200 0.030
Human Fly
regulation of cellular ketone metabolic process GO:0010565 3 0.030
response to alcohol GO:0097305 95 0.029
Human Fly
purine ribonucleotide metabolic process GO:0009150 145 0.029
regulation of cell differentiation GO:0045595 302 0.029
negative regulation of cellular biosynthetic process GO:0031327 277 0.029
response to alkaloid GO:0043279 26 0.029
Fly
purine containing compound metabolic process GO:0072521 155 0.028
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.028
Human Rat
forebrain development GO:0030900 2 0.028
negative regulation of developmental process GO:0051093 201 0.028
amine metabolic process GO:0009308 12 0.028
regulation of multi organism process GO:0043900 131 0.027
ribonucleotide biosynthetic process GO:0009260 28 0.027
response to abiotic stimulus GO:0009628 341 0.027
Fly
appendage development GO:0048736 401 0.027
adult behavior GO:0030534 137 0.027
Fly
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.027
Human Rat
male gamete generation GO:0048232 201 0.026
Fly
behavioral response to ethanol GO:0048149 49 0.026
Fly
axon guidance GO:0007411 233 0.026
synaptic transmission GO:0007268 288 0.026
Fly
cellular ketone metabolic process GO:0042180 24 0.026
lateral inhibition GO:0046331 206 0.025
imaginal disc derived wing morphogenesis GO:0007476 337 0.025
camera type eye development GO:0043010 4 0.025
organic hydroxy compound metabolic process GO:1901615 83 0.025
negative regulation of multicellular organismal process GO:0051241 142 0.025
actin filament based process GO:0030029 220 0.025
protein complex biogenesis GO:0070271 201 0.024
regulation of growth GO:0040008 233 0.024
nucleoside phosphate biosynthetic process GO:1901293 34 0.024
response to organic cyclic compound GO:0014070 89 0.024
Fly
axonogenesis GO:0007409 290 0.024
Fly
neuron recognition GO:0008038 101 0.024
transcription from rna polymerase ii promoter GO:0006366 368 0.023
multi multicellular organism process GO:0044706 123 0.023
Rat
positive regulation of biosynthetic process GO:0009891 316 0.023
Human Rat
macromolecular complex assembly GO:0065003 256 0.023
nucleoside phosphate metabolic process GO:0006753 162 0.023
regulation of molecular function GO:0065009 217 0.023
response to organonitrogen compound GO:0010243 75 0.023
Fly
ethanolamine containing compound metabolic process GO:0042439 4 0.023
g protein coupled receptor signaling pathway GO:0007186 136 0.022
Mouse Rat
regulation of multicellular organismal development GO:2000026 414 0.022
actin cytoskeleton organization GO:0030036 206 0.022
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 17 0.022
Mouse Rat
nucleobase containing small molecule metabolic process GO:0055086 174 0.022
medium chain fatty acid metabolic process GO:0051791 1 0.022
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.022
organic substance transport GO:0071702 257 0.021
protein modification process GO:0036211 438 0.021
positive regulation of catabolic process GO:0009896 105 0.021
negative regulation of purine nucleotide biosynthetic process GO:1900372 3 0.021
cellular amine metabolic process GO:0044106 12 0.021
homeostatic process GO:0042592 199 0.021
endocytosis GO:0006897 310 0.021
regulation of phosphorus metabolic process GO:0051174 210 0.020
Human Rat
cellular amino acid metabolic process GO:0006520 61 0.020
cellular protein modification process GO:0006464 438 0.020
regulation of cellular component biogenesis GO:0044087 201 0.020
regulation of catalytic activity GO:0050790 185 0.020
regulation of nucleotide metabolic process GO:0006140 62 0.020
Human Rat
protein complex assembly GO:0006461 200 0.020
regulation of catabolic process GO:0009894 170 0.020
negative regulation of gene expression GO:0010629 387 0.019
lipid metabolic process GO:0006629 121 0.019
intracellular transport GO:0046907 228 0.019
organic substance catabolic process GO:1901575 308 0.019
cellular lipid metabolic process GO:0044255 83 0.019
locomotory behavior GO:0007626 176 0.019
Fly
response to endoplasmic reticulum stress GO:0034976 28 0.019
eye development GO:0001654 323 0.019
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.019
cell death GO:0008219 279 0.019
memory GO:0007613 94 0.019
Fly
negative regulation of cell communication GO:0010648 223 0.018
muscle structure development GO:0061061 224 0.018
cell cell signaling involved in cell fate commitment GO:0045168 210 0.018
regulation of purine nucleotide metabolic process GO:1900542 62 0.018
Human Rat
cellular response to chemical stimulus GO:0070887 199 0.018
Human
phagocytosis GO:0006909 215 0.018
taxis GO:0042330 304 0.018
embryonic axis specification GO:0000578 107 0.017
oocyte differentiation GO:0009994 145 0.017
cellular response to organonitrogen compound GO:0071417 36 0.017
positive regulation of nucleotide metabolic process GO:0045981 55 0.017
Human Rat
imaginal disc pattern formation GO:0007447 91 0.017
single organism intracellular transport GO:1902582 207 0.017
protein catabolic process GO:0030163 101 0.017
regulation of synapse structure and activity GO:0050803 128 0.016
nucleotide metabolic process GO:0009117 161 0.016
carbohydrate metabolic process GO:0005975 82 0.016
establishment of localization in cell GO:0051649 402 0.016
secretion by cell GO:0032940 101 0.016
response to nitrogen compound GO:1901698 90 0.016
Fly
ribonucleotide metabolic process GO:0009259 145 0.016
negative regulation of signaling GO:0023057 219 0.016
positive regulation of cellular catabolic process GO:0031331 95 0.016
regulation of organelle organization GO:0033043 196 0.016
skin development GO:0043588 65 0.016
death GO:0016265 284 0.016
organic hydroxy compound biosynthetic process GO:1901617 21 0.016
organophosphate catabolic process GO:0046434 112 0.016
multicellular organismal reproductive behavior GO:0033057 110 0.016
membrane organization GO:0061024 112 0.016
regulation of localization GO:0032879 275 0.016
single organism catabolic process GO:0044712 228 0.016
detection of stimulus GO:0051606 156 0.016
Fly
learning or memory GO:0007611 141 0.015
Fly
imaginal disc derived appendage morphogenesis GO:0035114 395 0.015
regulation of immune effector process GO:0002697 52 0.015
maternal determination of anterior posterior axis embryo GO:0008358 74 0.015
response to biotic stimulus GO:0009607 294 0.015
central nervous system development GO:0007417 201 0.015
cellular response to endogenous stimulus GO:0071495 80 0.015
positive regulation of phosphorus metabolic process GO:0010562 139 0.015
Human Rat
cellular response to peptide hormone stimulus GO:0071375 28 0.015
cellular response to oxygen containing compound GO:1901701 79 0.015
Human
cognition GO:0050890 141 0.015
Fly
negative regulation of response to stimulus GO:0048585 258 0.015
regulation of developmental growth GO:0048638 174 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.015
glycerophospholipid metabolic process GO:0006650 23 0.015
wound healing GO:0042060 75 0.015
regulation of cellular localization GO:0060341 136 0.015
cellular catabolic process GO:0044248 372 0.014
phosphatidylethanolamine metabolic process GO:0046337 1 0.014
single organism cellular localization GO:1902580 180 0.014
positive regulation of gene expression GO:0010628 290 0.014
imaginal disc derived appendage development GO:0048737 399 0.014
protein phosphorylation GO:0006468 169 0.014
nitrogen compound transport GO:0071705 85 0.014
sensory perception of smell GO:0007608 80 0.014
wing disc morphogenesis GO:0007472 344 0.014
cellular homeostasis GO:0019725 80 0.014
organic acid metabolic process GO:0006082 103 0.014
cation transmembrane transport GO:0098655 88 0.014
adult locomotory behavior GO:0008344 76 0.014
regulation of programmed cell death GO:0043067 152 0.014
chemical homeostasis GO:0048878 92 0.014
protein localization GO:0008104 284 0.014
protein maturation GO:0051604 71 0.013
tripartite regional subdivision GO:0007351 103 0.013
detection of chemical stimulus involved in sensory perception of sweet taste GO:0001582 11 0.013
Fly
detection of chemical stimulus involved in sensory perception GO:0050907 75 0.013
Fly
positive regulation of macromolecule metabolic process GO:0010604 405 0.013
carbohydrate derivative metabolic process GO:1901135 217 0.013
secretion GO:0046903 109 0.013
organonitrogen compound catabolic process GO:1901565 128 0.013
circadian behavior GO:0048512 76 0.013
Fly
regulation of response to stress GO:0080134 200 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.013
cellular protein complex assembly GO:0043623 71 0.013
cellular response to nitrogen compound GO:1901699 51 0.013
axon development GO:0061564 297 0.013
Fly
cell recognition GO:0008037 102 0.013
response to decreased oxygen levels GO:0036293 58 0.013
regulation of phosphate metabolic process GO:0019220 210 0.012
Human Rat
epithelial cell differentiation GO:0030855 322 0.012
response to oxidative stress GO:0006979 86 0.012
Fly
oocyte anterior posterior axis specification GO:0007314 72 0.012
positive regulation of developmental process GO:0051094 143 0.012
mrna splicing via spliceosome GO:0000398 73 0.012
regulation of cellular protein metabolic process GO:0032268 243 0.012
establishment of protein localization GO:0045184 163 0.012
cellular response to organic substance GO:0071310 132 0.012
Human
regulation of cellular amine metabolic process GO:0033238 3 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.012
chaperone mediated protein folding GO:0061077 2 0.012
organelle localization GO:0051640 148 0.012
negative regulation of peptide hormone secretion GO:0090278 1 0.012
positive regulation of response to stimulus GO:0048584 323 0.012
response to purine containing compound GO:0014074 12 0.012
Fly
glycerolipid metabolic process GO:0046486 34 0.012
developmental maturation GO:0021700 172 0.012
segmentation GO:0035282 207 0.012
exocytosis GO:0006887 28 0.012
muscle organ development GO:0007517 127 0.012
rna processing GO:0006396 147 0.012
cytoplasm organization GO:0007028 64 0.012
lipid biosynthetic process GO:0008610 46 0.012
regulation of immune system process GO:0002682 176 0.012
cellular ion homeostasis GO:0006873 39 0.012
positive regulation of cell motility GO:2000147 3 0.011
cellular nitrogen compound catabolic process GO:0044270 165 0.011
actin filament polymerization GO:0030041 27 0.011
organelle assembly GO:0070925 198 0.011
peptidyl threonine phosphorylation GO:0018107 2 0.011
response to insulin GO:0032868 29 0.011
regulation of protein metabolic process GO:0051246 256 0.011
positive regulation of hydrolase activity GO:0051345 78 0.011
positive regulation of cell migration GO:0030335 2 0.011
cyclic purine nucleotide metabolic process GO:0052652 25 0.011
regulation of system process GO:0044057 36 0.011
Fly
vitamin metabolic process GO:0006766 2 0.011
regulation of nervous system development GO:0051960 248 0.011
regulation of cell development GO:0060284 215 0.011
regulation of cell death GO:0010941 173 0.011
regulation of cellular response to stress GO:0080135 89 0.011
actin polymerization or depolymerization GO:0008154 31 0.011
enzyme linked receptor protein signaling pathway GO:0007167 179 0.011
regulation of cellular catabolic process GO:0031329 157 0.011
organelle fission GO:0048285 340 0.011
photoreceptor cell development GO:0042461 96 0.011
regulation of reproductive process GO:2000241 54 0.011
response to light stimulus GO:0009416 124 0.011
retina development in camera type eye GO:0060041 4 0.011
response to wounding GO:0009611 94 0.011
organic cyclic compound catabolic process GO:1901361 168 0.011
dna metabolic process GO:0006259 227 0.011
regulation of transport GO:0051049 181 0.011
regulation of cellular component size GO:0032535 98 0.011
regulation of membrane potential GO:0042391 35 0.011
response to extracellular stimulus GO:0009991 116 0.010
anion transport GO:0006820 41 0.010
anterior posterior axis specification embryo GO:0008595 103 0.010
regulation of cell proliferation GO:0042127 163 0.010
positive regulation of rna biosynthetic process GO:1902680 266 0.010
anterior posterior pattern specification GO:0009952 136 0.010
positive regulation of nucleic acid templated transcription GO:1903508 266 0.010
response to other organism GO:0051707 293 0.010
monocarboxylic acid transport GO:0015718 3 0.010
appendage morphogenesis GO:0035107 397 0.010
actin filament organization GO:0007015 126 0.010
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 17 0.010
Mouse Rat
heterocycle catabolic process GO:0046700 166 0.010
positive regulation of molecular function GO:0044093 136 0.010
positive regulation of gtpase activity GO:0043547 43 0.010
negative regulation of signal transduction GO:0009968 206 0.010
programmed cell death GO:0012501 257 0.010

Ac76E disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.088
bone disease DOID:0080001 0 0.029
musculoskeletal system disease DOID:17 0 0.029
connective tissue disease DOID:65 0 0.029
nervous system disease DOID:863 0 0.021
vascular disease DOID:178 0 0.015
cardiovascular system disease DOID:1287 0 0.015
central nervous system disease DOID:331 0 0.012
neurodegenerative disease DOID:1289 0 0.012